Chronic stress effects on hippocampal structure and synaptic function: relevance for depression and normalization by anti-glucocorticoid treatment

Two new Later Stone Age sites from the Final Pleistocene in the Falémé Valley, eastern Senegal

Ndiaye, M., Lespez, L., Tribolo, C., Rassé, M., Hadjas, I., Davidoux, S., Huysecom, É., & Douze, K. (2024) · Monash University Research Portal (Monash University) · doi:10.3929/ethz-b-000667478 · Cited by 24,015 · see citing works

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,501 · see citing works

Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120 · see citing works

Physiology and neurobiology of stress and adaptation: central role of the brain

McEwen, B. S. (2007) · Physiological Reviews · doi:10.1152/physrev.00041.2006 · Cited by 4,981 · cited 1× · see citing works

Stress and the brain: from adaptation to disease

de Kloet, E. R., Joëls, M., & Holsboer, F. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1683 · Cited by 4,621 · see citing works

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science · doi:10.1126/science.1083328 · Cited by 4,321 · see citing works

Neural regulation of endocrine and autonomic stress responses

Ulrich-Lai, Y. M., & Herman, J. P. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2647 · Cited by 3,318 · see citing works

Mechanisms and Functional Implications of Adult Neurogenesis

Zhao, C., Deng, W., & Gage, F. H. (2008) · Cell · doi:10.1016/j.cell.2008.01.033 · Cited by 3,007 · see citing works

Glucocorticoids and Hippocampal Atrophy in Neuropsychiatric Disorders

Sapolsky, R. M. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.10.925 · Cited by 2,016 · see citing works

Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms

Pittenger, C., & Duman, R. S. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301574 · Cited by 1,795 · see citing works

Stress, memory and the amygdala

Roozendaal, B., McEwen, B. S., & Chattarji, S. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2651 · Cited by 1,760 · see citing works

The link between childhood trauma and depression: insights from HPA axis studies in humans

Heim, C., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.03.008 · Cited by 1,704 · see citing works

Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons

Vyas, A., Mitra, R., Shankaranarayana Rao, B. S., & Chattarji, S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-15-06810.2002 · Cited by 1,662 · see citing works

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

Clelland, C. D., Choi, M., Romberg, C., Clemenson, G. D., Fragniere, A., Tyers, P., Jessberger, S., Saksida, L. M., Barker, R. A., Gage, F. H., et al. (2009) · Science · doi:10.1126/science.1173215 · Cited by 1,642 · see citing works

The stressed hippocampus, synaptic plasticity and lost memories

Kim, J. J., & Diamond, D. M. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn849 · Cited by 1,543 · see citing works

The neuro-symphony of stress

Joëls, M., & Baram, T. Z. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2632 · Cited by 1,521 · see citing works

Regional dissociations within the hippocampus-memory and anxiety

Bannerman, D. M., Rawlins, J. N. P., McHugh, S. B., Deacon, R. M. J., Yee, B. K., Bast, T., Zhang, W.-N., Pothuizen, H. H. J., & Feldon, J. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.03.004 · Cited by 1,462 · see citing works

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression

David, D. J., Samuels, B. A., Rainer, Q., Wang, J.-W., Marsteller, D., Mendez, I., Drew, M., Craig, D. A., Guiard, B. P., Guilloux, J.-P., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.04.017 · Cited by 1,267 · see citing works

Adult hippocampal neurogenesis in depression

Sahay, A., & Hen, R. (2007) · Nature Neuroscience · doi:10.1038/nn1969 · Cited by 1,206 · see citing works

Untreated Depression and Hippocampal Volume Loss

Sheline, Y. I., Gado, M. H., & Kraemer, H. C. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.8.1516 · Cited by 1,180 · see citing works

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine

Czéh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., van Kampen, M., Bartolomucci, A., & Fuchs, E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.211427898 · Cited by 1,090 · see citing works

Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus

Lemaire, V., Koehl, M., Le Moal, M., & Abrous, D. N. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.20.11032 · Cited by 1,044 · cited 2× · see citing works

Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons

Woolley, C. S., Gould, E., & McEwen, B. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90778-a · Cited by 1,020 · see citing works

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

Saxe, M. D., Battaglia, F., Wang, J.-W., Malleret, G., David, D. J., Monckton, J. E., Garcia, A. D. R., Sofroniew, M. V., Kandel, E. R., Santarelli, L., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607207103 · Cited by 1,020 · see citing works

Stress-Induced Alterations in Prefrontal Cortical Dendritic Morphology Predict Selective Impairments in Perceptual Attentional Set-Shifting

Liston, C., Miller, M. M., Goldwater, D. S., Radley, J. J., Rocher, A. B., Hof, P. R., Morrison, J. H., & McEwen, B. S. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1184-06.2006 · Cited by 968 · see citing works

Chronic Psychosocial Stress Causes Apical Dendritic Atrophy of Hippocampal CA3 Pyramidal Neurons in Subordinate Tree Shrews

Magariños, A. M., McEwen, B. S., Flügge, G., & Fuchs, E. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-10-03534.1996 · Cited by 864 · see citing works

Psychosocial stress reversibly disrupts prefrontal processing and attentional control

Liston, C., McEwen, B. S., & Casey, B. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807041106 · Cited by 859 · see citing works

Chronic Stress Causes Frontostriatal Reorganization and Affects Decision-Making

Dias-Ferreira, E., Sousa, J. C., Melo, I., Morgado, P., Mesquita, A. R., Cerqueira, J. J., Costa, R. M., & Sousa, N. (2009) · Science · doi:10.1126/science.1171203 · Cited by 858 · see citing works

Repeated Stress Induces Dendritic Spine Loss in the Rat Medial Prefrontal Cortex

Radley, J. J., Rocher, A. B., Miller, M., Janssen, W. G. M., Liston, C., Hof, P. R., McEwen, B. S., & Morrison, J. H. (2006) · Cerebral Cortex · doi:10.1093/cercor/bhi104 · Cited by 820 · see citing works

Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone

Karst, H., Berger, S., Turiault, M., Tronche, F., Schütz, G., & Joëls, M. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507572102 · Cited by 774 · see citing works

Enhanced memory for emotional material following stress-level cortisol treatment in humans

Buchanan, T. W., & Lovallo, W. R. (2001) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(00)00058-5 · Cited by 762 · see citing works

Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement

Sousa, N., Lukoyanov, N. V., Madeira, M. D., Almeida, O. F. X., & Paula-Barbosa, M. M. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00050-6 · Cited by 758 · see citing works

Chronic stress alters dendritic morphology in rat medial prefrontal cortex

Cook, S. C., & Wellman, C. L. (2004) · Journal of Neurobiology · doi:10.1002/neu.20025 · Cited by 750 · see citing works

How widespread is adult neurogenesis in mammals?

Gould, E. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2147 · Cited by 658 · see citing works

Repeated restraint stress suppresses neurogenesis and induces biphasic PSA‐NCAM expression in the adult rat dentate gyrus

Pham, K., Nacher, J., Hof, P. R., & McEwen, B. S. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02513.x · Cited by 657 · see citing works

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

Jessberger, S., Clark, R. E., Broadbent, N. J., Clemenson, G. D., Consiglio, A., Lie, D. C., Squire, L. R., & Gage, F. H. (2009) · Learning & Memory · doi:10.1101/lm.1172609 · Cited by 654 · see citing works

Potential role for adult neurogenesis in the encoding of time in new memories

Aimone, J. B., Wiles, J., & Gage, F. H. (2006) · Nature Neuroscience · doi:10.1038/nn1707 · Cited by 644 · see citing works

Effects of adverse experiences for brain structure and function

McEwen, B. S. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00964-1 · Cited by 639 · see citing works

Neural stem cell proliferation is decreased in schizophrenia, but not in depression

Reif, A., Fritzen, S., Finger, M., Strobel, A., Lauer, M., Schmitt, A., & Lesch, K.-P. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001791 · Cited by 630 · see citing works

Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies

Garthe, A., Behr, J., & Kempermann, G. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005464 · Cited by 597 · see citing works

Spatial Relational Memory Requires Hippocampal Adult Neurogenesis

Dupret, D., Revest, J., Koehl, M., Ichas, F., Giorgi, F. D., Costet, P., Abrous, D. N., & Piazza, P. V. (2008) · PLoS ONE · doi:10.1371/journal.pone.0001959 · Cited by 595 · see citing works

Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration

Wellman, C. L. (2001) · Journal of Neurobiology · doi:10.1002/neu.1079 · Cited by 594 · see citing works

Gene×environment interactions at the serotonin transporter locus

Munafò, M. R., Durrant, C., Lewis, G., & Flint, J. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.06.009 · Cited by 576 · see citing works

Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: Comparison of stressors

Magarin˜os, A. M., & McEwen, B. S. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00256-i · Cited by 571 · see citing works

Is mood chemistry?

Castrén, E. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1629 · Cited by 563 · see citing works

Adult hippocampal neurogenesis is involved in anxiety-related behaviors

Revest, J.-M., Dupret, D., Koehl, M., Funk-Reiter, C., Grosjean, N., Piazza, P.-V., & Abrous, D. N. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.15 · Cited by 549 · see citing works

Chronic stress alters synaptic terminal structure in hippocampus

Magariños, A. M., Verdugo, J. M. G., & McEwen, B. S. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.14002 · Cited by 543 · see citing works

Sex differences in dendritic atrophy of CA3 pyramidal neurons in response to chronic restraint stress

Galea, L. A. M., McEwen, B. S., Tanapat, P., Deak, T., Spencer, R. L., & Dhabhar, F. S. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00233-9 · Cited by 540 · see citing works

Is there a link between adult neurogenesis and learning?

Leuner, B., Gould, E., & Shors, T. J. (2006) · Hippocampus · doi:10.1002/hipo.20153 · Cited by 530 · see citing works

A role for adult TLX-positive neural stem cells in learning and behaviour

Zhang, C., Zou, Y., He, W., Gage, F. H., & Evans, R. M. (2008) · Nature · doi:10.1038/nature06562 · Cited by 523 · see citing works

Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats

Bodnoff, S., Humphreys, A., Lehman, J., Diamond, D. M., Rose, G., & Meaney, M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00061.1995 · Cited by 522 · see citing works

Adult Neurogenesis Modulates the Hippocampus-Dependent Period of Associative Fear Memory

北村, 貴., Saitoh, Y., Takashima, N., Murayama, A., Niibori, Y., Ageta, H., Sekiguchi, M., Sugiyama, H., & Inokuchi, K. (2009) · Cell · doi:10.1016/j.cell.2009.10.020 · Cited by 489 · see citing works

Stress Hormone Regulation: Biological Role and Translation into Therapy

Holsboer, F., & Ising, M. (2010) · Annual Review of Psychology · doi:10.1146/annurev.psych.093008.100321 · Cited by 473 · see citing works

Brief Uncontrollable Stress Causes Dendritic Retraction in Infralimbic Cortex and Resistance to Fear Extinction in Mice

Izquierdo, A., Wellman, C. L., & Holmes, A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0474-06.2006 · Cited by 459 · see citing works

Structural Plasticity and Hippocampal Function

Leuner, B., & Gould, E. (2009) · Annual Review of Psychology · doi:10.1146/annurev.psych.093008.100359 · Cited by 452 · see citing works

Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action☆

Lucassen, P. J., Meerlo, P., Naylor, A. S., van Dam, A. M., Dayer, A. G., Fuchs, E., Oomen, C. A., & Czéh, B. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2009.08.003 · Cited by 449 · see citing works

Astroglial Plasticity in the Hippocampus is Affected by Chronic Psychosocial Stress and Concomitant Fluoxetine Treatment

Czéh, B., Simon, M., Schmelting, B., Hiemke, C., & Fuchs, E. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300982 · Cited by 434 · see citing works

What causes the hippocampal volume decrease in depression?: Are neurogenesis, glial changes and apoptosis implicated?

Czéh, B., & Lucassen, P. J. (2007) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-007-0728-0 · Cited by 419 · see citing works

Acute corticosterone treatment is sufficient to induce anxiety and amygdaloid dendritic hypertrophy

Mitra, R., & Sapolsky, R. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705615105 · Cited by 409 · see citing works

Depressed new Neurons?—Adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression

Kempermann, G., & Kronenberg, G. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00319-6 · Cited by 392 · see citing works

Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons

Dupret, D., Fabre, A., Döbrössy, M. D., Panatier, A., Rodriguez, J. J., Lamarque, S., Lemaire, V., Oliet, S. H. R., Piazza, P., & Abrous, D. N. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050214 · Cited by 387 · see citing works

Adrenal steroids and N-methyl-D-aspartate receptor activation regulate neurogenesis in the dentate gyrus of adult rats through a common pathway

Cameron, H. A., Tanapat, P., & Gould, E. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00303-5 · Cited by 381 · see citing works

Chronic stress: Implications for neuronal morphology, function and neurogenesis

Joëls, M., Karst, H., Krugers, H. J., & Lucassen, P. J. (2007) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.04.001 · Cited by 381 · see citing works

Effects of glucocorticoids and norepinephrine on the excitability in the hippocampus

Joëls, M., & de Kloet, E. R. (1989) · Science · doi:10.1126/science.2781292 · Cited by 375 · see citing works

Severe Early Life Stress Hampers Spatial Learning and Neurogenesis, but Improves Hippocampal Synaptic Plasticity and Emotional Learning under High-Stress Conditions in Adulthood

Oomen, C. A., Soeters, H., Audureau, N., Vermunt, L., van Hasselt, F. N., Manders, E. M. M., Joëls, M., Lucassen, P. J., & Krugers, H. J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0247-10.2010 · Cited by 352 · see citing works

Phenytoin prevents stress‐ and corticosterone‐induced atrophy of CA3 pyramidal neurons

Watanabe, Y., Gould, E., Cameron, H. A., Daniels, D. C., & McEwen, B. S. (1992) · Hippocampus · doi:10.1002/hipo.450020410 · Cited by 350 · see citing works

Mild, Short-term Stress Alters Dendritic Morphology in Rat Medial Prefrontal Cortex

Brown, S. M., Henning, S., & Wellman, C. L. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhi048 · Cited by 335 · see citing works

Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress

Magariños, A. M., Deslandes, A., & McEwen, B. S. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00163-6 · Cited by 330 · see citing works

Polymorphisms of the Glucocorticoid Receptor Gene and Major Depression

van Rossum, E. F. C., Binder, E. B., Majer, M., Koper, J. W., Ising, M., Modell, S., Salyakina, D., Lamberts, S. W. J., & Holsboer, F. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.007 · Cited by 324 · see citing works

Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis

Banasr, M., Soumier, A., Hery, M., Mocaër, E., & Daszuta, A. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.11.025 · Cited by 318 · see citing works

Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible

Heine, V. M., Maslam, S., Zareno, J., Joëls, M., & Lucassen, P. J. (2004) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.03100.x · Cited by 317 · see citing works

Effects of chronic stress on hippocampal long‐term potentiation

Pavlides, C., Nivón, L. G., & McEwen, B. S. (2002) · Hippocampus · doi:10.1002/hipo.1116 · Cited by 316 · see citing works

Prolonged behavioral stress enhances synaptic connectivity in the basolateral amygdala

Vyas, A., Jadhav, S., & Chattarji, S. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.003 · Cited by 299 · see citing works

Morphological Correlates of Corticosteroid-Induced Changes in Prefrontal Cortex-Dependent Behaviors

Cerqueira, J., Pêgo, J. M., Taipa, R. J. F., Bessa, J. M., Almeida, O. F. X., & Sousa, N. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1598-05.2005 · Cited by 285 · see citing works

Serotonin receptor binding in a colony model of chronic social stress

McKittrick, C. R., Blanchard, D. C., Blanchard, R. J., McEwen, B. S., & Sakai, R. R. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00152-s · Cited by 281 · see citing works

Stress models of depression: forming genetically vulnerable strains

Henn, F. A., & Vollmayr, B. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.019 · Cited by 274 · see citing works

Corticosteroid Modulation of Hippocampal Potentials: Increased Effect with Aging

Kerr, D. S., Campbell, L. W., Hao, S.-Y., & Landfield, P. W. (1989) · Science · doi:10.1126/science.2781293 · Cited by 271 · see citing works

Chronic unpredictable stress impairs long‐term potentiation in rat hippocampal CA1 area and dentate gyrus <i>in vitro</i>

Alfarez, D. N., Joëls, M., & Krugers, H. J. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02622.x · Cited by 258 · see citing works

Hippocampal neurogenesis as a target for the treatment of mental illness: A critical evaluation

DeCarolis, N. A., & Eisch, A. J. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.12.013 · Cited by 252 · see citing works

Clinical Features Associated with Glucocorticoid Receptor Polymorphisms: An Overview

Manenschijn, L., van den Akker, E. L. T., Lamberts, S. W. J., & van Rossum, E. F. C. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05013.x · Cited by 249 · see citing works

Glucocorticoids Enhance the Excitability of Principal Basolateral Amygdala Neurons

Duvarci, S., & Paré, D. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.0680-07.2007 · Cited by 249 · see citing works

Stress Impairs GABAergic Network Function in the Hippocampus by Activating Nongenomic Glucocorticoid Receptors and Affecting the Integrity of the Parvalbumin-Expressing Neuronal Network

Hu, W., Zhang, M., Czéh, B., Flügge, G., & Zhang, W. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.31 · Cited by 246 · see citing works

Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress

Hains, A. B., Vu, M. A. T., Maciejewski, P. K., van Dyck, C. H., Gottron, M., & Arnsten, A. F. T. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908563106 · Cited by 234 · see citing works

Effect of brain‐derived neurotrophic factor haploinsufficiency on stress‐induced remodeling of hippocampal neurons

Magariños, A. M., Li, C. J., Gal Toth, J., Bath, K. G., Jing, D., Lee, F. S., & McEwen, B. S. (2011) · Hippocampus · doi:10.1002/hipo.20744 · Cited by 232 · see citing works

Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress

Oomen, C. A., Mayer, J. L., de Kloet, E. R., Joëls, M., & Lucassen, P. J. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05972.x · Cited by 231 · see citing works

Reduced cell proliferation in the dentate gyrusis not correlated with the development of learned helplessness

Vollmayr, B., Simonis, C., Weber, S., Gass, P., & Henn, F. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00527-4 · Cited by 229 · see citing works

Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression

Heine, V. M., Zareno, J., Maslam, S., Joëls, M., & Lucassen, P. J. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.03951.x · Cited by 225 · see citing works

Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus

Pawlak, R., Rao, B. S. S., Melchor, J. P., Chattarji, S., McEwen, B., & Strickland, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509232102 · Cited by 223 · see citing works

Hippocampal neuroplasticity induced by early-life stress: Functional and molecular aspects

Fenoglio, K. A., Brunson, K. L., & Baram, T. (2006) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2006.02.001 · Cited by 215 · see citing works

Decreased numbers of progenitor cells but no response to antidepressant drugs in the hippocampus of elderly depressed patients

Lucassen, P. J., Stumpel, M. W., Wang, Q., & Aronica, E. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.01.012 · Cited by 213 · see citing works

What Is the Functional Significance of Chronic Stress-Induced CA3 Dendritic Retraction Within the Hippocampus?

Conrad, C. D. (2006) · Behavioral and Cognitive Neuroscience Reviews · doi:10.1177/1534582306289043 · Cited by 211 · see citing works

Maternal care influences neuronal survival in the hippocampus of the rat

Bredy, T. W., Grant, R. J., Champagne, D. L., & Meaney, M. J. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.02965.x · Cited by 208 · see citing works

Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex

Lucassen, P. J., Fuchs, E., & Czéh, B. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.12.014 · Cited by 201 · see citing works

Stress suppresses and learning induces plasticity in CA3 of rat hippocampus: A three-dimensional ultrastructural study of thorny excrescences and their postsynaptic densities

Stewart, M. G., Davies, H. A., Sandi, C., Kraev, I. V., Rogachevsky, V. V., Peddie, C. J., Rodriguez, J. J., Cordero, M. I., Donohue, H. S., Gabbott, P. L. A., et al. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.10.031 · Cited by 197 · see citing works

Rapid reversal of stress induced loss of synapses in CA3 of rat hippocampus following water maze training

Sandi, C., Davies, H. A., Cordero, M. I., Rodriguez, J. J., Popov, V. I., & Stewart, M. G. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02675.x · Cited by 194 · see citing works

Rapid changes in hippocampal CA1 pyramidal cell function via pre‐ as well as postsynaptic membrane mineralocorticoid receptors

Olijslagers, J. E., de Kloet, E. R., Elgersma, Y., van Woerden, G. M., Joëls, M., & Karst, H. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06220.x · Cited by 192 · see citing works

Opposite effects of early maternal deprivation on neurogenesis in male versus female rats

Oomen, C. A., Girardi, C. E. N., Cahyadi, R., Verbeek, E. C., Krugers, H., Joëls, M., & Lucassen, P. J. (2009) · PLoS ONE · doi:10.1371/journal.pone.0003675 · Cited by 190 · see citing works

The role of N ‐methyl‐ D ‐asparate receptors in neurogenesis

Nácher, J., & McEwen, B. S. (2006) · Hippocampus · doi:10.1002/hipo.20160 · Cited by 189 · see citing works

Suppression of adult neurogenesis leads to an increased hypothalamo-pituitary-adrenal axis response

Schloesser, R. J., Manji, H. K., & Martinowich, K. (2009) · Neuroreport · doi:10.1097/wnr.0b013e3283293e59 · Cited by 187 · see citing works

The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats

Kole, M. H. P., Swan, L., & Fuchs, E. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02136.x · Cited by 181 · see citing works

Brief Treatment With the Glucocorticoid Receptor Antagonist Mifepristone Normalises the Corticosterone‐Induced Reduction of Adult Hippocampal Neurogenesis

Mayer, J. L., Klumpers, L. E., Maslam, S., de Kloet, E. R., Joëls, M., & Lucassen, P. J. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01455.x · Cited by 181 · see citing works

The effects of chronic glucocorticoid exposure on dendritic length, synapse numbers and glial volume in animal models: Implications for hippocampal volume reductions in depression

Tata, D. A., & Anderson, B. J. (2010) · Physiology &amp; Behavior · doi:10.1016/j.physbeh.2009.09.008 · Cited by 173 · cited 2× · see citing works

Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers

Karst, H., Karten, Y. J. G., Reichardt, H. M., de Kloet, E. R., Schütz, G., & Joëls, M. (2000) · Nature Neuroscience · doi:10.1038/79910 · Cited by 171 · see citing works

Timing is essential for rapid effects of corticosterone on synaptic potentiation in the mouse hippocampus

Wiegert, O., Joëls, M., & Krugers, H. (2006) · Learning &amp; Memory · doi:10.1101/lm.87706 · Cited by 162 · see citing works

Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons

Karten, Y. J. G., Nair, S. M., van Essen, L., Sibug, R. M., & Joëls, M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13456 · Cited by 150 · see citing works

Ageing abolishes the effects of fluoxetine on neurogenesis

Couillard-Despres, S., Wuertinger, C., Kandasamy, M., Caioni, M., Stadler, K., Aigner, R., Bogdahn, U., & Aigner, L. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.147 · Cited by 143 · see citing works

Modulation of Different States of Anxiety-Like Behavior by Chronic Stress.

Vyas, A., & Chattarji, S. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.6.1450 · Cited by 136 · see citing works

Adult Hippocampal Neurogenesis as Target for the Treatment of Depression

Drew, M. R., & Hen, R. (2007) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152707780619353 · Cited by 130 · see citing works

Synapse loss from chronically elevated glucocorticoids: Relationship to neuropil volume and cell number in hippocampal area CA3

Tata, D. Α., Marciano, V. A., & Anderson, B. J. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.21071 · Cited by 130 · see citing works

Attenuating corticosterone levels on the day of memory assessment prevents chronic stress‐induced impairments in spatial memory

Wright, R. L., Lightner, E. N., Harman, J. S., Meijer, O. C., & Conrad, C. D. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04948.x · Cited by 128 · see citing works

Effect of Chronic Stress on Synaptic Currents in Rat Hippocampal Dentate Gyrus Neurons

Karst, H., & Joëls, M. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00691.2002 · Cited by 111 · see citing works

Stress selectively and lastingly promotes learning of context-related high arousing information

Smeets, T., Wolf, O. T., Giesbrecht, T., Sijstermans, K., Telgen, S., & Joëls, M. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.03.001 · Cited by 104 · see citing works

Blockade of glucocorticoid receptors rapidly restores hippocampal CA1 synaptic plasticity after exposure to chronic stress

Krugers, H. J., Goltstein, P. M., van der Linden, S., & Joëls, M. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04842.x · Cited by 102 · see citing works

Daily injections alter spine density in rat medial prefrontal cortex

Seib, L. M., & Wellman, C. L. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(02)01287-9 · Cited by 100 · see citing works

Bidirectional shift in the cornu ammonis 3 pyramidal dendritic organization following brief stress

Kole, M. H. P., Costoli, T., Koolhaas, J. M., & Fuchs, E. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.02.014 · Cited by 96 · see citing works

Chronic psychosocial stress does not affect the number of pyramidal neurons in tree shrew hippocampus

Vollmann-Honsdorf, G. K., Flügge, G., & Fuchs, E. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00647-2 · Cited by 96 · see citing works

The use of mifepristone in the treatment of neuropsychiatric disorders

DeBattista, C., & Belanoff, J. K. (2006) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2006.02.006 · Cited by 96 · see citing works

Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived Neural Precursor Cells Through GSK-3β and β-Catenin/TCF Pathway

Boku, S., Nakagawa, S., Masuda, T., Nishikawa, H., Kato, A., Kitaichi, Y., Inoue, T., & Koyama, T. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.198 · Cited by 88 · see citing works

Activity-stress induces atrophy of apical dendrites of hippocampal pyramidal neurons in male rats

Lambert, K. G., Buckelew, S. K., Staffiso-Sandoz, G., Gaffga, S., Carpenter, W., Fisher, J. M., & Kinsley, C. H. (1998) · Physiology & Behavior · doi:10.1016/s0031-9384(98)00114-0 · Cited by 87 · see citing works

Implication of corticosteroid receptors in the regulation of hippocampal structural plasticity

Montaron, M., Piazza, P. V., Aurousseau, C., Urani, A., Moal, M. L., & Abrous, D. N. (2003) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2003.03048.x · Cited by 82 · see citing works

Corticosterone reduces dendritic complexity in developing hippocampal CA1 neurons

Alfarez, D. N., Simoni, A. D., Velzing, E. H., Bracey, E. F., Joëls, M., Edwards, F. A., & Krugers, H. J. (2009) · Hippocampus · doi:10.1002/hipo.20566 · Cited by 81 · see citing works

Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic-like symptoms in rats

Jayatissa, M. N., Henningsen, K., West, M. J., & Wiborg, O. (2009) · Brain Research · doi:10.1016/j.brainres.2009.07.001 · Cited by 79 · see citing works

Untreated Depression and Hippocampal Volume Loss

Carroll, B. J. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1309-a · Cited by 75 · see citing works

Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons

Riel, E. V., Meijer, O. C., Steenbergen, P. J., & Joëls, M. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00355-5 · Cited by 64 · see citing works

A multisite trial of mifepristone for the treatment of psychotic depression: A site-by-treatment interaction

Blasey, C. M., DeBattista, C., Roe, R., Block, T., & Belanoff, J. K. (2009) · Contemporary Clinical Trials · doi:10.1016/j.cct.2009.03.001 · Cited by 61 · see citing works

Increased P27KIP1 protein expression in the dentate gyrus of chronically stressed rats indicates G1 arrest involvement

Heine, V. M., Maslam, S., Joëls, M., & Lucassen, P. J. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.07.048 · Cited by 54 · see citing works

Differential Effects of Corticosterone on the Slow Afterhyperpolarization in the Basolateral Amygdala and CA1 Region: Possible Role of Calcium Channel Subunits

Liebmann, L., Karst, H., Sidiropoulou, K., van Gemert, N. G., Meijer, O. C., Poirazi, P., & Joëls, M. (2007) · Journal of Neurophysiology · doi:10.1152/jn.01137.2007 · Cited by 51 · see citing works

Brief RU 38486 Treatment Normalizes the Effects of Chronic Stress on Calcium Currents in Rat Hippocampal CA1 Neurons

Karst, H., & Joëls, M. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301296 · Cited by 47 · see citing works

Impaired Declarative Memory in Depressed Patients Is Slow To Recover: Clinical Experience

Deuschle, M., Kniest, A., Niemann, H., Erb-Bies, N., Colla, M., Hamann, B., & Heuser, I. (2004) · Pharmacopsychiatry · doi:10.1055/s-2004-827168 · Cited by 44 · see citing works

Dissociation between Rat Hippocampal CA1 and Dentate Gyrus Cells in Their Response to Corticosterone: Effects on Calcium Channel Protein and Current

van Gemert, N. G., Carvalho, D. M., Karst, H., van der Laan, S., Zhang, M., Meijer, O. C., Hell, J. W., & Joëls, M. (2009) · Endocrinology · doi:10.1210/en.2009-0525 · Cited by 43 · see citing works

Opposite effects of glucocorticoid receptor activation on hippocampal CA1 dendritic complexity in chronically stressed and handled animals

Alfarez, D. N., Karst, H., Velzing, E. H., Joëls, M., & Krugers, H. J. (2007) · Hippocampus · doi:10.1002/hipo.20360 · Cited by 39 · see citing works

Preliminary Evidence That Hippocampal Volumes in Monkeys Predict Stress Levels of Adrenocorticotropic Hormone

Lyons, D. M., Parker, K. J., Zeitzer, J. M., Buckmaster, C. L., & Schatzberg, A. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.012 · Cited by 34 · see citing works

Effect of Chronic Stress and Mifepristone Treatment on Voltage‐Dependent Ca2+ Currents in Rat Hippocampal Dentate Gyrus

van Gemert, N. G., & Joëls, M. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01472.x · Cited by 34 · see citing works

Effects of NADH on dopamine release in rat striatum

Pearl, S. M., Antion, M. D., Stanwood, G. D., Jaumotte, J. D., Kapatos, G., & Zigmond, M. J. (2000) · Synapse · doi:10.1002/(sici)1098-2396(200005)36:2 · Cited by 9 · see citing works

Local potentiation of excitatory synapses by serotonin and its alteration in rodent models of depression

Cai, X., Kallarackal, A. J., Kvarta, M. D., Goluskin, S., Gaylor, K., Bailey, A. M., Lee, H.-K., Huganir, R. L., & Thompson, S. M. (2013) · Nature Neuroscience · doi:10.1038/nn.3355 · Cited by 180 · see citing works

Neuroendocrine Regulation of Brain Cytokines After Psychological Stress

Johnson, J. D., Barnard, D. F., Kulp, A. C., & Mehta, D. M. (2019) · Journal of the Endocrine Society · doi:10.1210/js.2019-00053 · Cited by 135 · see citing works

Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress

Maras, P. M., Molet, J., Chen, Y., Rice, C., Ji, S. G., Solodkin, A., & Baram, T. Z. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.12 · Cited by 118 · see citing works

Towards an Integrative Account of Potential Mechanisms Mediating the Path From Sleep Dysfunction to Hallucinations

Sheaves, B., Cropley, V. L., Moseley, P., Woodruff, P. W. R., Punton, G., Speth, C., Speth, J., Meerlo, P., & Brederoo, S. G. (2025) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf107 · Cited by 6 · see citing works

Protective effect of naoyikang on D-gal-induced injury in cultured hippocampal neurons

Hu, Y.-E. (2006) · Journal of Nantong University

Effection of polychlorinated biphenyls in cultured hippocampal neuronic cells of rats

Yuhong, W. (2002) · Medical Journal of National Defending Forces in Northwest China

Protective effect of brain-derived neurotrophic factor on Aβ25-35-induced hippocampal neuron injury

Tian, Y. (2011)

On normalization of inconsistency indicators in pairwise comparisonsPreprint

Koczkodaj, W. W., Magnot, J.-P., Mazurek, J., et al. (2017) · arXiv (Cornell University) · doi:10.48550/arxiv.1702.07205

On Batch Orthogonalization LayersPreprint

Blanchette, & Laganière (2018) · arXiv (Cornell University) · doi:10.48550/arxiv.1812.03049 · Cited by 1 · see citing works