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Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors
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“The main factors affecting GIT absorption of the drug is drug physicochemical characteristics (polymorphism, solubility, partition coefficient, and pH-pKa), biological factors (blood flow at absorption site, mucus, absorption surface area, ionic concentration, enzymes, and microbiome) as well as maintenance of sync condition (drug concentration at the absorption site).76”
From Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment (2022) · cites this paper as [76]
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Metadata
- Authors
- Hua, S.
- Venue
- Frontiers in Pharmacology
- Publisher
- Frontiers Media SA
- Published
- 2020-04-28
- Volume
- 11
- ISSN
- 1663-9812
- PMC
- PMC7212533
- Cited by
- 527
- References
- 12
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