Cited by 2,936Diabetes, Cardiovascular Risks, and LipoproteinsCardiovascular Function and Risk FactorsCardiovascular Health and Risk Factors

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Diabetes and Cardiovascular Disease: The Framingham Study

Kannel, William B.·1979·JAMA

DOI 10.1001/jama.1979.03290450033020

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Abstract

Based on 20 years of surveillance of the Framingham cohort relating subsequent cardiovascular events to prior evidence of diabetes, a twofold to threefold increased risk of clinical atherosclerotic disease was reported. The relative impact was greatest for intermittent claudication (IC) and congestive heart failure (CHF) and least for coronary heart disease (CHD), which was, nevertheless, on an absolute scale the chief sequela. The relative impact was substantially greater for women than for men. For each of the cardiovascular diseases (CVD), morbidity and mortality were higher for diabetic women than for nondiabetic men. After adjustment for other associated risk factors, the relative impact of diabetes on CHD, IC, or stroke incidence was the same for women as for men; for CVD death and CHF, it was greater for women. Cardiovascular mortality was actually about as great for diabetic women as for diabetic men. (JAMA241:2035-2038, 1979)

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Authors: Kannel, W. B.
Corresponding author: Kannel, William B.
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 1979-05-11
Volume: 241
Issue: 19
Pages: 2035
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.1979.03290450033020
OpenAlex: W4252437054
Cited by: 2,936
References: 0
Citations by year: 2026: 41 · 2025: 63 · 2024: 82 · 2023: 81 · 2022: 97 · 2021: 135 · 2020: 118 · 2019: 144 · 2018: 127 · 2017: 133 · 2016: 100 · 2015: 89 · 2014: 87 · 2013: 86 · 2012: 125
FWCI: 6.91
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords: diabetes mellitus, cardiovascular disease, cardiovascular risk, atherosclerosis, intermittent claudication, congestive heart failure, coronary artery disease, stroke, cardiovascular mortality, sex differences, Framingham cohort, cardiovascular morbidity

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Diabetes and Cardiovascular Disease: The Framingham Study

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