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microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases
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“Dysregulation of microRNA (miRNA) expression in the brain is a common feature of neurodegenerative diseases.”
From Neurodegenerative disease-associated microRNAs acting as signaling molecules modulate CNS neuron structure and viability (2025) · cites this paper as [12]
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The widespread regulation of microRNA biogenesis, function and decay
Krol, J., Loedige, I., & Filipowicz, W. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2843 · Cited by 4,672
A pancreatic islet-specific microRNA regulates insulin secretion
Poy, M. N., Eliasson, L., Krutzfeldt, J., Kuwajima, S., Ma, X., MacDonald, P. E., Pfeffer, S., Tuschl, T., Rajewsky, N., Rorsman, P., et al. (2004) · Nature · doi:10.1038/nature03076 · Cited by 2,102
A brain-specific microRNA regulates dendritic spine development
Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., & Greenberg, M. E. (2006) · Nature · doi:10.1038/nature04367 · Cited by 1,786
Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., & Ambros, V. (2004) · Genome Biology · doi:10.1186/gb-2004-5-3-r13 · Cited by 1,578
Kim, D., Nguyen, M. D., Dobbin, M. M., Fischer, A., Sananbenesi, F., Rodgers, J. T., Delalle, I., Baur, J. A., Sui, G., Armour, S. M., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601758 · Cited by 1,074
A novel pathway regulates memory and plasticity via SIRT1 and miR-134
Gao, J., Wang, W.-Y., Mao, Y.-W., Gräff, J., Guan, J.-S., Pan, L., Mak, G., Kim, D., Su, S. C., & Tsai, L.-H. (2010) · Nature · doi:10.1038/nature09271 · Cited by 975
Cogswell, J. P., Ward, J., Taylor, I. A., Waters, M., Shi, Y., Cannon, B., Kelnar, K., Kemppainen, J., Brown, D., Chen, C., et al. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-14103 · Cited by 943
Molecular pathways to neurodegeneration
Bossy-Wetzel, E., Schwarzenbacher, R., & Lipton, S. A. (2004) · Nature Medicine · doi:10.1038/nm1067 · Cited by 740
LNA (Locked Nucleic Acid): High-Affinity Targeting of Complementary RNA and DNA
Vester, B., & Wengel, J. (2004) · Biochemistry · doi:10.1021/bi0485732 · Cited by 727
Packer, A. N., Xing, Y., Harper, S. Q., Jones, L., & Davidson, B. L. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2390-08.2008 · Cited by 679
Repression of α-synuclein expression and toxicity by microRNA-7
Junn, E., Lee, K.-W., Jeong, B. S., Chan, T. W., Im, J.-Y., & Mouradian, M. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906277106 · Cited by 634
Sequence-specific inhibition of small RNA function
Hutvágner, G., Simard, M. J., Mello, C. C., & Zamore, P. D. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020098 · Cited by 584
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
Butovsky, O., Siddiqui, S., Gabriely, G., Lanser, A. J., Dake, B., Murugaiyan, G., Doykan, C. E., Wu, P. M., Gali, R. R., Iyer, L. K., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci62636 · Cited by 481
MicroRNA regulation of Alzheimer's Amyloid precursor protein expression
Hébert, S. S., Horré, K., Nicolaï, L., Bergmans, B., Papadopoulou, A. S., Delacourte, A., & De Strooper, B. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2008.11.009 · Cited by 436
Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice
Koval, E. D., Shaner, C., Zhang, P., du Maine, X., Fischer, K., Tay, J., Chau, B. N., Wu, G. F., & Miller, T. M. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt261 · Cited by 236
MiRNA Profile in the Substantia Nigra of Parkinson’s Disease and Healthy Subjects
Cardo, L. F., Coto, E., Ribacoba, R., Menéndez, M., Moris, G., Suárez, E., & Alvarez, V. (2014) · Journal of Molecular Neuroscience · doi:10.1007/s12031-014-0428-y · Cited by 75
Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation
Manakov, S. A., Grant, S. G., & Enright, A. J. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-419 · Cited by 34
MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms
Delay, C., Dorval, V., Fok, A., Grenier-Boley, B., Lambert, J.-C., Hsiung, G.-Y., & Hébert, S. S. (2014) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2014.00067 · Cited by 28
Research works printed but not linked: 137
- International Human Genome Sequencing Consortium (2001) Initial sequencing and analysis of the human genome. Nature 409:860–921 · DOI · Paper page
- Huttenhofer A, Schattner P, Polacek N (2005) Non-coding RNAs: hope or hype? Trends Genet 21:289–297 · DOI
- Kaikkonen MU, Lam MT, Glass CV (2011) Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovasc Res 90:430–440 · DOI · Paper page
- Ardekani AM, Naeini MM (2010) The role of microRNAs in human diseases. Avicenna J Med Biotechnol 2:161–179
- Li Y, Kowdley KV (2012) MicroRNAs in common human diseases. Genomics Proteomics Bioinform 10:246–253 · DOI
- Etheridge A, Lee I, Hood L, Galas D, Wang K (2011) Extracellular microRNA: a new source of biomarker. Mutat Res 717:85–90 · DOI
- Jeffrey SS (2008) Cancer biomarker profiling with microRNAs. Nat Biotechnol 26:400–401 · DOI
- Goodall EF, Heath PR, Bandmann O, Kirby J, Shaw PJ (2013) neuronal dark matter: the emerging role of microRNAs in neurodegeneration. Front Cell Neurosci 7:178 · DOI · Paper page
- Cathew RW, Sontheimer EJ (2009) Origins and mechanisms of miRNAs and siRNAs. Cell 136:642–655 · DOI
- Kim VN, Han J, Siomi MC (2009) Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 10:126–139 · DOI · Paper page
- Siomi H, Siomi MC (2010) Posttranscriptional regulation of microRNA biogenesis in animals. Mol Cell 38:323–332 · DOI
- Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281–297 · DOI
- Lee Y, Ahn C, Han J et al (2003) The nuclear RNase III Drosha initiates micorRNA processing. Nature 425:415–419 · DOI
- Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN (2004) The Drosha–DGCR8 complex in primary microRNA processing. Genes Dev 18:3016–3027 · DOI
- Gregory RI, Yan KP, Amuthan G et al (2004) The microprocessor complex mediates the genesis of microRNAs. Nature 432:235–240 · DOI
- MacRae IJ, Ma E, Zhou M, Robinson CV, Doudna JA (2008) In vitro reconstitution of the human RISC-loading complex. Proc Natl Acad Sci USA 105:512–517 · DOI
- Ruby JG, Jan CH, Bartel DP (2007) Intronic microRNA precursors that bypass Drosha processing. Nature 448:83–86 · DOI · Paper page
- Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R (2008) Mouse ES cells express endogenous shRNAs, siRNAs, and other microprocessor-independent, Dicer-dependent small RNAs. Genes Dev 22:2773–2785 · DOI
- Ender C, Krek A, Friedlander MR et al (2008) A human snoRNA with microRNA-like functions. Mol Cell 32:519–528 · DOI
- Miyoshi K, Miyoshi T, Siomi H (2010) Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production. Mol Genet Genomics 284:95–103 · DOI
- Vasudevan S (2012) Posttranscriptional upregulation by microRNAs. Wiley Interdiscip Rev RNA 3:311–330 · DOI
- Hashimoto Y, Akiyama Y, Yuasa Y (2013) Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer. PLoS One 8:e62589 · DOI
- Han J, Pederson JS, Kwon SC et al (2009) Posttranscriptional crossregulation between Drosha and DGCR8. Cell 136:75–84 · DOI
- Triboulet R, Chang HM, LaPierre RJ, Gregory RI (2009) Post-transcriptional control of DGCR8 expression by the microprocessor. RNA 15:1005–1011 · DOI
- Newman MA, Hammond SM (2010) Emerging paradigms of regulated microRNA processing. Genes Dev 24:1086–1092 · DOI
- Hammond SM, Boettcher S, Caudy AA, Kobayashi R, Hannon GJ (2001) Argonaute 2, a link between genetic and biochemical analyses of RNAi. Science 293:1146–1150 · DOI · Paper page
- Heale BSE, Keegan LP, McGurk L et al (2009) Editing independent effects of ADARs on the miRNA/siRNA pathways. EMBO J 28:3145–3156 · DOI
- Zhang Z, Qin YW, Brewer G, Jing Q (2012) MicroRNA degradation and turnover: regulating the regulators. Wiley Interdiscip Rev RNA 3:593–600 · DOI
- Sim SE, Bakes J, Kaang BK (2014) Neuronal activity-dependent regulation of microRNAs. Mol Cells 37:511–517 · DOI
- Lim LP, Lau NC, Garrett-Engele A, Grimson JM et al (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433:769–773 · DOI · Paper page
- Esau C, Davis S, Murray SF, Yu XX, Pandey SK et al (2006) miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab 3:87–98 · DOI · Paper page
- Khalaj M, Tavakkoli M, Stranahan AW, Park CY (2014) Pathogenic microRNA’s in myeloid malignancies. Front Genet 5:361 · DOI
- Simone NL, Soule BP, Ly D, Saleh AD et al (2009) Ionizing-induced oxidative stress alters miRNA expression. PLoS One 4:e6377 · DOI
- Kuss AW, Chen W (2008) MicroRNAs in brain function and disease. Curr Neurol Neurosci Rep 8:190–197 · DOI
- Shi Y, Zhao X, Hsieh J, Wichterle H et al (2010) MicroRNA regulation of neural stem cells and neurogenesis. J Neurosci 30:14931–14936 · DOI
- Giraldez AJ, Cinalli RM, Glasner ME et al (2005) MicroRNAs regulate brain morphogenesis in zebrafish. Science 308:833–838 · DOI · Paper page
- Chen JA, Wichterle H (2012) Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci 6:69
- Yang D, Li T, Wang Y et al (2012) miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression. J Cell Sci 125:1673–1682 · DOI
- Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, Murchison E et al (2007) A microRNA feedback circuit in midbrain dopamine neurons. Science 317:1220–1224 · DOI · Paper page
- Haramati S, Chapnik E, Sztainberg Y, Eilam R, Zwang R, Gershoni N et al (2010) miRNA malfunction causes spinal motor neuron disease. Proc Natl Acad Sci USA 107:13111–13116 · DOI
- Schaefer A, O’Carroll D, Tan CL, Hillman D, Sugimori M, Llinas R et al (2007) Cerebellar neurodegeneration in the absence of microRNAs. J Exp Med 204:1553–1558 · DOI · Paper page
- Krichevsky AM, Sonntag KC, Isacson O, Kosik KS (2006) Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells 23:857–864 · DOI · Paper page
- Conaco C, Otto S, Han JJ, Mandel G (2006) Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci USA 103:2422–2427 · DOI · Paper page
- Makeyev EV, Zhang J, Carrasco MA, Maniatis T (2007) The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 27:435–448 · DOI · Paper page
- Bruno IG, Karam R, Huang L et al (2011) Identification of microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Mol Cell 42:500–510 · DOI
- Zhou R, Yuan P, Wang Y et al (2009) Evidence of selective microRNAs and their effectors as common long-term targets for the action of mood stabilizers. Neuropsychopharmacology 34:1395–1405 · DOI
- Olde Loohuis NF, Kos A, Martens GJ et al (2012) MicroRNA networks direct neuronal development and plasticity. Cell Mol Life Sci 69:89–102 · DOI
- Margis R, Margis R, Rieder CR (2011) Identification of blood microRNAs associated to Parkinson’s disease. J Biotechnol 152:96–101 · DOI · Paper page
- Geekiyanage H, Jicha GA, Nelson PT, Chan C (2012) Blood serum miRNA: non-invasive biomarkers for Alzheimer’s disease. Exp Neurol 235:491–496 · DOI
- Vallelunga A, Ragusa M, DiMauro S et al (2014) Identification of circulating microRNAs for the differential diagnosis of Parkinson’s disease and multiple system atrophy. Front Cell Neurosci 8:156 · DOI
- Hébert SS, Horré K, Nicolaï L et al (2008) Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer’s disease correlates with increased BACE1/β-secretase expression. Proc Natl Acad Sci USA 105:6415–6420 · DOI · Paper page
- Lee ST, Chu K, Im WS (2011) Altered microRNA regulation in Huntington’s disease models. Exp Neurol 227:172–179 · DOI · Paper page
- Wang WX, Huang Q, Hu Y, Stromberg AJ, Nelson PT (2011) Patterns of microRNA expression in normal and early Alzheimer’s disease human temporal cortex: white matter versus gray matter. Acta Neuropathol 121:193–205 · DOI · Paper page
- Geekiyanage H, Chan C (2011) MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid beta, novel targets in sporadic Alzheimer’s disease. J Neurosci 31:14820–14830 · DOI · Paper page
- Abdullah R, Basak I, Patil KS, Alves G, Larsen JP, Moller SG (2014) Parkinson’s disease and age: the obvious but largely unexplored link. Exp Gerontol 68:33–38 · DOI
- Inukai S, de Lencastre A, Turner M, Slack F (2012) Novel microRNAs differentially expressed during aging in the mouse brain. PLoS One 7:e40028 · DOI
- Persengiev S, Kondova I, Otting N, Koeppen AH, Bontrop RE (2011) Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis. Neurobiol Aging 32:e2317–e2327 · DOI
- Elfenbein HA, Rosen RF, Stephens SL et al (2007) Cerebral β-amyloid angiopathy in aged squirrel monkeys. Histol Histopathol 22:155–167
- Martinez I, Almstead LL, DiMaio D (2011) MicroRNAs and senescence. Aging 3:77–78 · DOI
- Li X, Khanna A, Li N, Wang E (2011) Circulatory miR34a as an RNA based, noninvasive biomarker for brain aging. Aging 3:985–1002 · DOI
- Smit-McBride Z, Forward KI, Nguyen AT (2014) Age-dependent increase in miR-34a expression in the posterior pole of the mouse eye. Mol Vis 20:1569–1578
- Alvarez-Erviti L, Seow Y, Schapira AH, Rodriguez-Oroz MC, Obeso JA, Cooper JM (2013) Influence of microRNA deregulation on chaperone-mediated autophagy and alpha-synuclein pathology in Parkinson’s disease. Cell Death Dis 4:e545 · DOI
- Burgos K, Malenica I, Metpally R et al (2014) Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer’s and Parkinson’s diseases correlate with disease status and features of pathology. PLoS One 9:e94839 · DOI · Paper page
- Lukiw WJ (2007) MiRNA speciation in fetal, adult and Alzheimer’s disease hippocampus. NeuroReport 18:297–300 · DOI · Paper page
- Saba R, Goodman CD, Huzarewich RLCH, Robertson C, Booth SA (2008) A miRNA signature of prion induced neurodegeneration. PLoS One 3:e3652 · DOI · Paper page
- Montag J, Hitt R, Opitz L (2009) Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease. Mol Neurodegener 4:36 · DOI
- Bellingham SA, Coleman BM, Hill AF (2012) Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Nucleic Acids Res 40:10937–10949 · DOI
- Cummings CJ, Zoghbi HY (2000) Fourteen and counting: unravelling trinucleotide repeat diseases. Hum Mol Genet 9:909–916 · DOI
- Everett CM, Wood NW (2004) Trinucleotide repeats and neurodegenerative disease. Brain 127:2385–2405 · DOI
- Pogue AI, Cui JG, Li YY, Chao Y, Culicchia F, Lukiw WJ (2010) MicroRNA-125b (miRNA-125b) function in astrogliosis and glial cell proliferation. Neurosci Lett 476:18–22 · DOI
- Marti E, Pantano L, Banez-Coronel M et al (2010) A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing. Nucleic Acids Res 38:7219–7235 · DOI · Paper page
- Johnson R, Buckley NJ (2009) Gene dysregulation in Huntington’s disease: REST, microRNAs and beyond. Neuromol Med 11:183–199 · DOI
- Basu U, Guan LL, Moore SS (2012) Functional genomics approach or identification of molecular processes underlying neurodegenerative disorders in prion diseases. Curr Genomics 13:369–378 · DOI
- Jellinger KA (2010) Basic mechanisms of neurodegeneration: a critical update. J Cell Mol Med 14:457–487 · DOI
- Lynch-Day MA, Mao K, Wang K, Zhao M, Klionsky DJ (2012) The role of autophagy in Parkinson’s disease. Cold Spring Harb Perspect Med 2:a009357
- Schapira AH, Gegg M (2011) Mitochondrial contribution to Parkinson’s disease pathogenesis. Parkinsons Dis 2011:159160
- Gibbings D, Mostowy S, Jay F, Schwab Y, Cossart P, Voinnet O (2012) Selective autophagy degrades DICER and AGO2 and regulates miRNA activity. Nat Cell Biol 14:1314–1321 · DOI
- Majeski AE, Dice JF (2004) Mechanisms of chaperone-mediated autophagy. Int J Biochem Cell Biol 36:2435–2444 · DOI
- Yang J, Chen D, He Y et al (2013) MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9. Age 35:11–22 · DOI
- Zhu H, Wu H, Liu X et al (2009) Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy 5:816–823 · DOI
- Williams AH, Valdez G, Moresi V et al (2009) MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science 326:1549–1554 · DOI · Paper page
- Roccaro AM, Sacco A, Jia X et al (2010) microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia. Blood 116:1506–1514 · DOI
- Gilad S, Meiri E, Yogev Y et al (2008) Serum microRNAs are promising novel biomarkers. PLoS One 3:e3148 · DOI
- Chen X, Ba Y, Ma L et al (2008) Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18:997–1006 · DOI · Paper page
- Lang AE, Lozano AM (1998) Parkinson’s disease—first of two parts. N Engl J Med 339:1044–1053 · DOI
- Martins M, Rosa A, Guedes LC et al (2011) Convergence of miRNA expression profiling, α-synuclein interaction and GWAS in Parkinson’s disease. PLoS One 6:e25443 · DOI
- Khoo SK, Petillo D, Kang UJ et al (2012) Plasma-based circulating microRNA biomarkers for Parkinson’s disease. J Parkinsons Dis 2:321–331 · DOI
- Schipper HM, Maes OC, Chertkow HM, Wang E (2007) microRNA expression in Alzheimer blood mononuclear cells. Gene Regul Syst Biol 1:263–274
- Leidinger P, Backes C, Deutscher S et al (2013) A blood based 12-miRNA signature of Alzheimer disease patients. Genome Biol 14:R78 · DOI
- Kumar P, Dezso Z, MacKenzie C et al (2013) Circulating miRNA biomarkers for Alzheimer’s disease. PLoS One 8:e69807 · DOI
- De Felice B, Guida M, Guida M, Coppola C, de Mieri G, Cotrufo RA (2012) miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis. Gene 508:35–40 · DOI
- Doxakis E (2010) Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153. J Biol Chem 285:12726–12734 · DOI · Paper page
- Gehrke S, Imai Y, Sokol N, Lu B (2010) Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression. Nature 466:637–641 · DOI
- Cho HJ, Liu G, Jin SM et al (2014) MicroRNA-205 regulates the expression of Parkinson’s disease-related leucine-rich repeat kinase 2 protein. Hum Mol Genet 22:608–620 · DOI
- Miñones-Moyano E, Porta S, Escaramís G et al (2011) MicroRNA profiling of Parkinson’s disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function. Hum Mol Genet 20:3067–3078 · DOI
- Dickson JR, Kruse C, Montagna DR, Finsen B, Wolfe MS (2013) Alternative polyadenylation and miR-34 family members regulate tau expression. J Neurochem 127:739–749 · DOI
- Long JM, Lahiri DK (2011) MicroRNA-101 downregulates Alzheimer’s amyloid-β precursor protein levels in human cell cultures and is differentially expressed. Biochem Biophys Res Commun 404:889–895 · DOI
- Liu W, Liu C, Zhu J et al (2012) MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer’s-associated pathogenesis in SAMP8 mice. Neurobiol Aging 33:522–534 · DOI
- Patel N, Hoang D, Miller N et al (2008) MicroRNAs can regulate human APP levels. Mol Neurodegener 3:10 · DOI
- Delay C, Calon F, Mathews P, Hébert SS (2011) Alzheimer-specific variants in the 3′UTR of Amyloid precursor protein affect microRNA function. Mol Neurodegener 6:70 · DOI
- Li YY, Cui JG, Hill JM, Bhattacharjee S, Zhao Y et al (2011) Increased expression of miRNA-146a in Alzheimer’s disease transgenic mouse models. Neurosci Lett 487:94–98 · DOI · Paper page
- Hu YK, Wang X, Li L, Du YH, Ye HT, Li CY (2013) MicroRNA-98 induces an Alzheimer’s disease-like disturbance by targeting insulin-like growth factor 1. Neurosci Bull 29:745–775 · DOI
- Wang WX, Wilfred BR, Madathil SK (2010) miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease. Am J Pathol 177:334–345 · DOI
- Fang M, Wang J, Zhang X et al (2012) The miR-124 regulates the expression of BACE1/p-secretase correlated with cell death in Alzheimer’s disease. Toxicol Lett 209:94–105 · DOI
- Cheng PH, Li CL, Chang YF et al (2013) miR-196a ameliorates phenotypes of Huntington disease in cell, transgenic mouse, and induced pluripotent stem cell models. Am Hum Genet 93:306–312 · DOI · Paper page
- Rademakers R, Eriksen JL, Baker M et al (2008) Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum Mol Genet 17:3631–3642 · DOI
- Jiang J, Lee EJ, Gusev Y, Schmittgen TD (2005) Real-time expression profiling of microRNA precursors in human cancer cells. Nucleic Acids Res 33:5394–5403 · DOI
- Lu DP, Read RL, Humphreys DT, Battah FM, Martin DI, Rasko JE (2005) PCR-based expression analysis and identification of microRNAs. J RNAi Gene Silencing 1:44–49
- Chen C, Ridzon DA, Broomer AJ et al (2005) Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 33:e179 · DOI
- Soreq L, Salomonis N, Bronstein M et al (2013) Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes. Front Mol Neurosci 6:10 · DOI
- Wang Z (2009) miRNA mimic technology. miRNA interference technologies. Springer, Berlin Heidelberg, pp 93–100 · DOI
- Boutla A, Delidakis C, Tabler M (2003) Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes. Nucleic Acids Res 31:4973–4980 · DOI
- Ebert MS, Neilson JR, Sharp PA (2007) MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods 4:721–726 · DOI · Paper page
- Xiao J, Yang B, Lin H, Lu Y, Luo X, Wang Z (2007) Novel approaches for gene-specific interference via manipulating actions of microRNAs: examination of the pacemaker channel genes HCN2 and HCN4. J Cell Physiol 212:285–292 · DOI
- Tan H, Poidevin M, Li H, Chen D, Jin P (2012) MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats. PLoS Genet 8:e1002681 · DOI
- Wang Z (2011) The principles of MiRNA-masking antisense oligonucleotide technology. Methods Mol Biol 676:43–49 · DOI
- Gumireddy K, Young DD, Xiong X, Hogenesch JB, Huang Q, Deiters A (2008) Small-molecular inhibitors of miR-21 function. Angew Chem Int Ed Engl 47:7482–7484 · DOI
- Serafin A, Foco L, Zanigni S et al (2015) Overexpression of blood microRNAs 103a, 30b, and 29a in l-dopa-treated patients with PD. Neurology 84:645–653 · DOI
- Garzon R, Marcucci G, Croce CM (2014) Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov 9:775–789 · DOI
- Miller TM, Pestronk A, David W et al (2013) An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomized, first-in-man study. Lancet Neurol 12:435–442 · DOI · Paper page
- Xu G, Fewell C, Taylor C et al (2010) Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq. RNA 16:1610–1622 · DOI
- Thomson DW, Bracken CP, Goodall GJ (2011) Experimental strategies for microRNA target identification. Nucleic Acids Res 39:6845–6853 · DOI · Paper page
- Chi SW, Zang JB, Mele A, Darnell RB (2009) Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps. Nature 460:479–486 · DOI · Paper page
- Hafner M, Landthaler M, Burger L et al (2010) Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141:129–141 · DOI · Paper page
- Yang JH, Li JH, Jiang S, Zhou H, Qu LH (2013) ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and miRNA genes from ChIP-Seq data. Nucleic Acids Res 41:D177–D187 · DOI
- Li C, Xiong Q, Zhang J, Ge F, Bi LJ (2012) Quantitative proteomic strategies for the identification of microRNA targets. Expert Rev Proteomics 9:549–559 · DOI
- Kurata R, Yonezawa T, Nakajima H, Takada S, Asahara H (2012) LC-MS/MS-based shotgun proteomics identified the targets of arthritis related microRNA. Arthritis Res Ther 14:P36 · DOI
- Cardo LF, Coto E, de Mena L, Ribacoba R, Moris G, Menéndez M et al (2013) Profile of microRNAs in the plasma of Parkinson’s disease patients and healthy controls. J Neurol 260:1420–1422 · DOI
- Alexandrov PN, Dua P, Hill JM, Bhattacharjee S, Zhao Y, Lukiw WJ (2012) microRNA (miRNA) speciation in Alzheimer’s disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF). Int J Biochem Mol Biol 3:365–373
- Shioya M, Obayashi S, Tabunoki H et al (2010) Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3. Neuropathol Appl Neurobiol 36:320–330 · DOI · Paper page
- Gaughwin PM, Ciesla M, Lahiri N, Tabrizi SJ, Brundin P, Björkqvist M (2011) Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington’s disease. Hum Mol Genet 20:2225–2237 · DOI · Paper page
- Lee ST, Chu K, Jung KH et al (2014) Altered expression of miR-202 in cerebellum of multiple-system atrophy. Mol Neurobiol 51:180–186
- Campos-Melo D, Droppelmann CA, He Z, Volkening K, Strong MJ (2013) Altered microRNA expression profile in amyotrophic lateral sclerosis: a role in the regulation of NFL mRNA levels. Mol Brain 6:26 · DOI
- Kabaria S, Choi DC, Chaudhuri AD, Mouradian MM, Junn E (2015) Inhibition of miR-34b and miR-34c enhances alpha-synuclein expression in Parkinson’s disease. FEBS Lett 589:319–325 · DOI
- Wang G, van der Walt JM, Mayhew G et al (2008) Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. Am J Hum Genet 82:283–289 · DOI
- Asikainen S, Rudgalvyte M, Heikkinen L et al (2010) Global microRNA expression profiling of Caenorhabditis elegans Parkinson’s disease models. J Mol Neurosci 41:210–218 · DOI · Paper page
- Yao J, Hennessey T, Flynt A, Lai E, Beal MF, Lin MT (2010) MicroRNA-related cofilin abnormality in Alzheimer’s disease. PLoS One 5:e15546 · DOI
Cited by
Sorted by citations
Kumbol, V., Ivanov, A., McGurran, H., Schüler, J., Zhai, Y., Ludwik, K., Hinkelmann, L., Brehm, M., Krüger, C., Küchler, J., et al. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02199-8 · Cited by 8
Metadata
- Authors
- Basak, I., Patil, K. S., Alves, G., Larsen, J. P., & Møller, S. G.
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2015-11-25
- Volume
- 73
- Issue
- 4
- Pages
- 811-827
- ISSN
- 1420-682X
- 1420-9071
- Cited by
- 107
- References
- 18
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
- Funders
- Norwegian Centre for Movement Disorders
- The Western Norway Health Authority
- The Norwegian Parkinson's Disease Association
- The Norwegian Centre of Movement Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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