Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

Vale, W., Spiess, J., Rivier, C., & Rivier, J. (1981) · Science · doi:10.1126/science.6267699 · Cited by 3,965

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

Vale, W., Spiess, J., RIVIER, C. L., & Rivier, J. (1982) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-198205000-00013 · Cited by 3,904

Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study

Swanson, L. W., Sawchenko, P. E., Rivier, J., & Vale, W. W. (2008) · Neuroendocrinology · doi:10.1159/000123454 · Cited by 1,953

Species-specific defense reactions and avoidance learning

Bolles, R. C. (1970) · Psychological Review · doi:10.1037/h0028589 · Cited by 1,610

Stress hormones: their interaction and regulation

Axelrod, J., & Reisine, T. D. (1984) · Science · doi:10.1126/science.6143403 · Cited by 1,527

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485

NEURAL CONTROL OF THE PITUITARY GLAND

Harris, G. W. (1948) · Physiological Reviews · doi:10.1152/physrev.1948.28.2.139 · Cited by 903

Hypothalamic Control of Adrenocorticotropin Secretion: Advances since the Discovery of 41-Residue Corticotropin-Releasing Factor

Antoni, F. A. (1986) · Endocrine Reviews · doi:10.1210/edrv-7-4-351 · Cited by 888

Corticotropin releasing factor produces behavioural activation in rats

Sutton, R., Koob, G., le Moal, M., Rivier, J., & Vale, W. (1982) · Nature · doi:10.1038/297331a0 · Cited by 744

Anatomical specificity of noradrenergic inputs to the paraventricular and supraoptic nuclei of the rat hypothalamus

Cunningham, E. T., & Sawchenko, P. E. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902740107 · Cited by 727

What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?

Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127

The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies

Heim, C., & Nemeroff, C. B. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01157-x · Cited by 2,791

Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations

Meaney, M. J. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1161 · Cited by 2,708

The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes

Berridge, C. W., & Waterhouse, B. D. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00143-7 · Cited by 2,529

Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity

BOYCE, W. T., & ELLIS, B. J. (2005) · Development and Psychopathology · doi:10.1017/s0954579405050145 · Cited by 2,078

Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood

Heim, C. (2000) · JAMA · doi:10.1001/jama.284.5.592 · Cited by 1,968

Nongenomic Transmission Across Generations of Maternal Behavior and Stress Responses in the Rat

Francis, D., Diorio, J., Liu, D., & Meaney, M. J. (1999) · Science · doi:10.1126/science.286.5442.1155 · Cited by 1,965

Biological studies of post-traumatic stress disorder

Pitman, R. K., Rasmusson, A. M., Koenen, K. C., Shin, L. M., Orr, S. P., Gilbertson, M. W., Milad, M. R., & Liberzon, I. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3339 · Cited by 1,529

Regional dissociations within the hippocampus-memory and anxiety

Bannerman, D. M., Rawlins, J. N. P., McHugh, S. B., Deacon, R. M. J., Yee, B. K., Bast, T., Zhang, W.-N., Pothuizen, H. H. J., & Feldon, J. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.03.004 · Cited by 1,462

Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety

Davis, M., Walker, D. L., Miles, L., & Grillon, C. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.109 · Cited by 1,513

Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat

Caldji, C., Tannenbaum, B., Sharma, S., Francis, D., Plotsky, P. M., & Meaney, M. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.9.5335 · Cited by 1,437

The role of corticotropin-releasing factor in depression and anxiety disorders

Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378

CRF and CRF receptors: role in stress responsivity and other behaviors

Bale, T. L., & Vale, W. W. (2004) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121410 · Cited by 1,270

Fear and anxiety: Animal models and human cognitive psychophysiology

Lang, P. J., Davis, M., & Öhman, A. (2000) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00343-8 · Cited by 1,162

Neuroendocrine pharmacology of stress

Carrasco, G. A., & Van de Kar, L. D. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01285-8 · Cited by 914

Glucocorticoids, prenatal stress and the programming of disease

Harris, A., & Seckl, J. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.06.007 · Cited by 871

Neurobiology of relapse to heroin and cocaine seeking: a review

Shalev, U., Grimm, J. W., & Shaham, Y. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.1.1 · Cited by 880

Stress dysregulation of drug reward pathways, and the transition to drug dependence

Koob, & Kreek, M. J. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.05030503 · Cited by 868

Prenatal glucocorticoids and long-term programming

Seckl (2004) · European Journal of Endocrinology · doi:10.1530/eje.0.151u049 · Cited by 825

Altered Pituitary-Adrenal Axis Responses to Provocative Challenge Tests in Adult Survivors of Childhood Abuse

Heim, C., Newport, D. J., Bonsall, R., Miller, A. H., & Nemeroff, C. B. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.4.575 · Cited by 746

Brain–Gut Interactions in Inflammatory Bowel Disease

Bonaz, B. L., & Bernstein, C. N. (2013) · Gastroenterology · doi:10.1053/j.gastro.2012.10.003 · Cited by 667

Central Oxytocin Administration Reduces Stress-Induced Corticosterone Release and Anxiety Behavior in Rats1

Windle, R. J., Shanks, N., Lightman, S. L., & Ingram, C. D. (1997) · Endocrinology · doi:10.1210/en.138.7.2829 · Cited by 170

PSYCHONEUROENDOCRINOLOGY OF DEPRESSION

Plotsky, P. M., Owens, M. J., & Nemeroff, C. B. (1998) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70006-x · Cited by 672

The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety

Holsboer, F. (1999) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(98)90056-5 · Cited by 654

Prenatal exposure to maternal depression and cortisol influences infant temperament

DAVIS, E. P., GLYNN, L. M., SCHETTER, C. D., HOBEL, C., CHICZ-DEMET, A., & SANDMAN, C. A. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318047b775 · Cited by 628

Corticotropin-releasing factor, norepinephrine, and stress

Koob, G. F. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00164-x · Cited by 629

Prenatal stress, glucocorticoids and the programming of the brain

Welberg, L. A. M., & Seckl, J. R. (2001) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2001.00601.x · Cited by 928

Psychosocial stress and impaired sleep

Åkerstedt, T. (2006) · Scandinavian Journal of Work, Environment & Health · doi:10.5271/sjweh.1054 · Cited by 585

Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis

Pich, E., Lorang, M., Yeganeh, M., Rodriguez de Fonseca, F., Raber, J., Koob, G., & Weiss, F. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-08-05439.1995 · Cited by 565

Glucocorticoid Programming

SECKL, J. R., & MEANEY, M. J. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1314.006 · Cited by 556

Regulation of affect by the lateral septum: implications for neuropsychiatry

Sheehan, T. P., Chambers, R. A., & Russell, D. S. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.04.009 · Cited by 514

Basic organization of projections from the oval and fusiform nuclei of the bed nuclei of the stria terminalis in adult rat brain

Dong, H., Petrovich, G. D., Watts, A. G., & Swanson, L. W. (2001) · Journal of Comparative Neurology · doi:10.1002/cne.1079 · Cited by 521

Long term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring

Plotsky, P. M., Thrivikraman, K. V., Nemeroff, C. B., Caldji, C., Sharma, S., & Meaney, M. J. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300769 · Cited by 522

Importance of studying the contributions of early adverse experience to neurobiological findings in depression

Heim, C., Plotsky, P. M., & Nemeroff, C. B. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300397 · Cited by 514

Chronic pain, chronic stress and depression: Coincidence or consequence?

Blackburn‐Munro, G., & Blackburn‐Munro, R. E. (2001) · Journal of Neuroendocrinology · doi:10.1046/j.0007-1331.2001.00727.x · Cited by 493

Addiction as a stress surfeit disorder

Koob, G. F., Buck, C. L., Cohen, A., Edwards, S., Park, P. E., Schlosburg, J. E., Schmeichel, B., Vendruscolo, L. F., Wade, C. L., Whitfield, T. W., et al. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.05.024 · Cited by 483

Role of the Hippocampus, the Bed Nucleus of the Stria Terminalis, and the Amygdala in the Excitatory Effect of Corticotropin-Releasing Hormone on the Acoustic Startle Reflex

Lee, Y., & Davis, M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-16-06434.1997 · Cited by 457

The role of early adverse experience and adulthood stress in the prediction of neuroendocrine stress reactivity in women: a multiple regression analysis

Heim, C., Newport, D. J., Wagner, D., Wilcox, M. M., Miller, A. H., & Nemeroff, C. B. (2002) · Depression and Anxiety · doi:10.1002/da.10015 · Cited by 433

Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression. Potential implications for the sexual dimophism of the stress response and immune/inflammatory reaction.

Vamvakopoulos, N. C., & Chrousos, G. P. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116782 · Cited by 422

Implication of the hypothalamic-pituitary-adrenal axis in the physiopathology of depression

Barden, N. (2004) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0421 · Cited by 416

Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal

Rassnick, S., Heinrichs, S. C., Britton, K. T., & Koob, G. F. (1993) · Brain Research · doi:10.1016/0006-8993(93)91352-s · Cited by 407

Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2

Radulovic, J., Rühmann, A., Liepold, T., & Spiess, J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-12-05016.1999 · Cited by 402

Corticosterone effects on corticotropin-releasing hormone mRNA in the central nucleus of the amygdala and the parvocellular region of the paraventricular nucleus of the hypothalamus

Makino, S., Gold, P. W., & Schulkin, J. (1994) · Brain Research · doi:10.1016/0006-8993(94)91862-7 · Cited by 400

Addiction is a Reward Deficit and Stress Surfeit Disorder

Koob, G. F. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00072 · Cited by 397

Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor

Valdez, G. R., Roberts, A. J., Chan, K., Davis, H., Brennan, M., Zorrilla, E. P., & Koob, G. F. (2002) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2002.tb02448.x · Cited by 387

Sex differences in anxiety and emotional behavior

Donner, N. C., & Lowry, C. A. (2013) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-013-1271-7 · Cited by 379

Human Bed Nucleus of the Stria Terminalis Indexes Hypervigilant Threat Monitoring

Somerville, L. H., Whalen, P. J., & Kelley, W. M. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.04.002 · Cited by 351

The dexamethasone/corticotropin-releasing factor test in men with major depression: role of childhood trauma

Heim, C., Mletzko, T., Purselle, D., Musselman, D. L., & Nemeroff, C. B. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.07.002 · Cited by 353

Corticotropin-Releasing Factor, But Not Corticosterone, Is Involved in Stress-Induced Relapse to Heroin-Seeking in Rats

Shaham, Y., Funk, D., Erb, S., Brown, T. J., Walker, C.-D., & Stewart, J. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-07-02605.1997 · Cited by 308

The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction

Burkett, J. P., & Young, L. J. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2794-x · Cited by 307

CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor 1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats

Shaham, Y., Erb, S., Leung, S., Buczek, Y., & Stewart, J. (1998) · Psychopharmacology · doi:10.1007/s002130050608 · Cited by 302

Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome

Sagami, Y., Shimada, Y., Tayama, J., Nomura, T., Satake, M., Endo, Y., Shoji, T., Karahashi, K., Hongo, M., & Fukudo, S. (2004) · Gut · doi:10.1136/gut.2003.018911 · Cited by 291

Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats

Funk, C. K., Zorrilla, E. P., Lee, M.-J., Rice, K. C., & Koob, G. F. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.063 · Cited by 276

Amygdala and bed nucleus of the stria terminalis: differential roles in fear and anxiety measured with the acoustic startle reflex

The American Association for Research into Nervous and Mental Diseases, Davis, M., Walker, D. L., & Lee, Y. (1997) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1997.0149 · Cited by 254

Brain corticotropin-releasing factor mediates ‘anxiety-like’ behavior induced by cocaine withdrawal in rats

Sarnyai, Z., Bíró, É., Gardi, J., Vecsernyés, M., Julesz, J., & Telegdy, G. (1995) · Brain Research · doi:10.1016/0006-8993(95)00043-p · Cited by 255

Glucocorticoids, developmental ‘programming’ and the risk of affective dysfunction

Seckl, J. R. (2007) · Progress in Brain Research · doi:10.1016/s0079-6123(07)67002-2 · Cited by 245

Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake

Olive, M. F., Koenig, H. N., Nannini, M. A., & Hodge, C. W. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00748-1 · Cited by 237

The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress**This research was supported by NIMH Grant MH-50479 and the Undergraduate Research Opportunities Program at the University of Colorado at Boulder.

Deak, T., Nguyen, K. T., Ehrlich, A. L., Watkins, L. R., Spencer, R. L., Maier, S. F., Licinio, J., Wong, M.-L., Chrousos, G. P., Webster, E., et al. (1999) · Endocrinology · doi:10.1210/endo.140.1.6415 · Cited by 242

Projections from the lateral part of the central amygdalar nucleus to the postulated fear conditioning circuit

Petrovich, G. D., & Swanson, L. W. (1997) · Brain Research · doi:10.1016/s0006-8993(96)01361-3 · Cited by 234

Role of stress, corticotrophin releasing factor (CRF) and amygdala plasticity in chronic anxiety

Shekhar, A., Truitt, W., Rainnie, D., & Sajdyk, T. (2005) · Stress · doi:10.1080/10253890500504557 · Cited by 237

Glucocorticoid “Programming” and PTSD Risk

SECKL, J. R., & MEANEY, M. J. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.027 · Cited by 234

Consequences of post-weaning social isolation on anxiety behavior and related neural circuits in rodents

Lukkes, J. L. (2009) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.018.2009 · Cited by 235

Cytokines and their receptors in the central nervous system: Physiology, pharmacology, and pathology

Rothwell, N. J., Luheshi, G., & Toulmond, S. (1996) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(95)02033-0 · Cited by 233

Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats

Liebsch, G., Landgraf, R., Gerstberger, R., Probst, J. C., Wotjak, C. T., Engelmann, M., Holsboer, F., & Montkowski, A. (1995) · Regulatory Peptides · doi:10.1016/0167-0115(95)00099-w · Cited by 220

Salivary alpha amylase-cortisol asymmetry in maltreated youth

Gordis, E. B., Granger, D. A., Susman, E. J., & Trickett, P. K. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.09.002 · Cited by 211

Behavioral effects of neuropeptides in rodent models of depression and anxiety

Rotzinger, S., Lovejoy, D. A., & Tan, L. A. (2010) · Peptides · doi:10.1016/j.peptides.2009.12.015 · Cited by 211

The Role of Life Events and HPA Axis in Anxiety Disorders: A Review

Faravelli, C., Lo Sauro, C., Lelli, L., Pietrini, F., Lazzeretti, L., Godini, L., Benni, L., Fioravanti, G., Alina Talamba, G., Castellini, G., et al. (2012) · Current Pharmaceutical Design · doi:10.2174/138161212803530907 · Cited by 208

The hypothalamic-pituitary-adrenal axis and the female reproductive system

MAGIAKOU, M. A., MASTORAKOS, G., WEBSTER, E., & CHROUSOS, G. P. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb52128.x · Cited by 320

Clonidine blocks stress-induced reinstatement of heroin seeking in rats: an effect independent of locus coeruleus noradrenergic neurons

Shaham, Y., Highfield, D., Delfs, J., Leung, S., & Stewart, J. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00899.x · Cited by 201

Childhood stressful events, HPA axis and anxiety disorders

Faravelli, C. (2012) · World Journal of Psychiatry · doi:10.5498/wjp.v2.i1.13 · Cited by 198

Nucleus accumbens corticotropin-releasing factor increases cue-triggered motivation for sucrose reward: paradoxical positive incentive effects in stress?

Peciña, S., Schulkin, J., & Berridge, K. C. (2006) · BMC Biology · doi:10.1186/1741-7007-4-8 · Cited by 194

Glucocorticoids, chronic stress, and obesity

Dallman, M. F., Pecoraro, N. C., La Fleur, S. E., Warne, J. P., Ginsberg, A. B., Akana, S. F., Laugero, K. C., Houshyar, H., Strack, A. M., Bhatnagar, S., et al. (2006) · Progress in Brain Research · doi:10.1016/s0079-6123(06)53004-3 · Cited by 198

Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist

Mansbach, R. S., Brooks, E. N., & Chen, Y. L. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(97)00025-3 · Cited by 195

Adaptation to potential threat: the evolution, neurobiology, and psychopathology of the security motivation system

Woody, E. Z., & Szechtman, H. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.08.003 · Cited by 195

The Pulsatile Characteristics of Hypothalamo-Pituitary-Adrenal Activity in Female Lewis and Fischer 344 Rats and Its Relationship to Differential Stress Responses*

Windle, R. J., Wood, S. A., Lightman, S. L., & Ingram, C. D. (1998) · Endocrinology · doi:10.1210/endo.139.10.6238 · Cited by 201

Role of Noradrenergic Projections to the bed nucleus of the stria terminalis in the Regulation of the Hypothalamic-Pituitary-Adrenal Axis

Forray, M. I., & Gysling, K. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.07.011 · Cited by 191

High-priority communication I Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence

Valdez, G. R., Zorrilla, E. P., Roberts, A. J., & Koob, G. F. (2003) · Alcohol · doi:10.1016/s0741-8329(03)00020-x · Cited by 186

The neuroanatomy and neuroendocrinology of fragile X syndrome

Hessl, D., Rivera, S. M., & Reiss, A. L. (2004) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20004 · Cited by 165

Stress is a principal factor that promotes tobacco use in females

Torres, O. V., & O'Dell, L. E. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.04.005 · Cited by 164

Brain Circuits Involved in Corticotropin‐Releasing Factor‐Norepinephrine Interactions during Stress

DUNN, A. J., SWIERGIEL, A. H., & PALAMARCHOUK, V (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1296.003 · Cited by 155

Overexpression of CB2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice

García-Gutiérrez, M. S., & Manzanares, J. (2011) · Journal of Psychopharmacology · doi:10.1177/0269881110379507 · Cited by 153

The Effect of Lateral Septum Corticotropin-Releasing Factor Receptor 2 Activation on Anxiety Is Modulated by Stress

Henry, B., Vale, W., & Markou, A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1494-06.2006 · Cited by 147

Anti-Stress Action of a Corticotropin-Releasing Factor Antagonist on Behavioral Reactivity to Stressors of Varying Type and Intensity

Heinrichs, S. C., Menzaghi, F., Pich, E. M., Baldwin, H. A., Rassnick, S., Britton, K. T., & Koob, G. F. (1994) · Neuropsychopharmacology · doi:10.1038/sj.npp.1380104 · Cited by 143

Role of corticotropin-releasing hormone in the amygdala and bed nucleus of the stria terminalis in the behavioral, pain modulatory, and endocrine consequences of opiate withdrawal

McNally, G. P., & Akil, H. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00105-7 · Cited by 141

Increased Anxiety‐Like Behavior and Ethanol Self‐Administration in Dependent Rats: Reversal via Corticotropin‐Releasing Factor‐2 Receptor Activation

Valdez, G. R., Sabino, V., & Koob, G. F. (2004) · Alcoholism: Clinical and Experimental Research · doi:10.1097/01.alc.0000128222.29875.40 · Cited by 131

Antagonism of CRF2 receptors produces anxiolytic behavior in animal models of anxiety

Takahashi, L. K., Ho, S. P., Livanov, V., Graciani, N., & Arneric, S. P. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02405-2 · Cited by 132

Involvement of Central Amygdalar and Bed Nucleus of the Stria Terminalis Corticotropin-Releasing Factor in Behavioral Responses to Social Defeat.

Jasnow, A. M., Davis, M., & Huhman, K. L. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.5.1052 · Cited by 118

Modulation of binding sites for corticotropin-releasing hormone by chronic psychosocial stress

Fuchs, E., & Flügge, G. (1995) · Psychoneuroendocrinology · doi:10.1016/0306-4530(94)e0006-u · Cited by 118

Corticotropin-releasing hormone during pregnancy is associated with infant temperament

Davis, E. P., Glynn, L. M., Dunkel Schetter, C., Hobel, C., Chicz-Demet, A., & Sandman, C. A. (2005) · Developmental Neuroscience · doi:10.1159/000086709 · Cited by 116

Impaired diurnal adrenal rhythmicity restored by constant infusion of corticotropin-releasing hormone in corticotropin-releasing hormone-deficient mice.

Muglia, L. J., Jacobson, L., Weninger, S. C., Luedke, C. E., Bae, D. S., Jeong, K. H., & Majzoub, J. A. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119487 · Cited by 115

Behavioral and anatomical interactions between dopamine and corticotropin-releasing factor in the rat

Meloni, E. G., Gerety, L. P., Knoll, A. T., Cohen, B. M., & Carlezon, W. A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4957-05.2006 · Cited by 109

The central corticotropin releasing factor system during development and adulthood

Korosi, A., & Baram, T. Z. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.066 · Cited by 102

Evidence for the role of corticotropin-releasing factor in major depressive disorder

Waters, R. P., Rivalan, M., Bangasser, D. A., Deussing, J. M., Ising, M., Wood, S. K., Holsboer, F., & Summers, C. H. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.07.011 · Cited by 93

Paraventricular nucleus of the human hypothalamus in primary hypertension: Activation of corticotropin-releasing hormone neurons

Goncharuk, V. D., Van Heerikhuize, J., Swaab, D. F., & Buijs, R. M. (2002) · Journal of Comparative Neurology · doi:10.1002/cne.10124 · Cited by 97

Corticotrophin‐releasing factor produces a long‐lasting enhancement of synaptic efficacy in the hippocampus

Wang, H. L., Wayner, M. J., Chai, C. Y., & Lee, E. H. Y. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00352.x · Cited by 97

Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior

Fox, J. H., & Lowry, C. A. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00169 · Cited by 93

Neural-immune interactions in the regulation of sleep

Opp, M. R. (2003) · Frontiers in Bioscience · doi:10.2741/1061 · Cited by 92

Progesterone Attenuates Corticotropin-Releasing Factor-Enhanced But Not Fear-Potentiated Startle via the Activity of Its Neuroactive Metabolite, Allopregnanolone

Toufexis, D. J., Davis, C., Hammond, A., & Davis, M. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1386-04.2004 · Cited by 86

Effects of acute treadmill running at different intensities on activities of serotonin and corticotropin-releasing factor neurons, and anxiety- and depressive-like behaviors in rats

Otsuka, T., Nishii, A., Amemiya, S., Kubota, N., Nishijima, T., & Kita, I. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.10.055 · Cited by 86

Long-lasting consequences of neonatal maternal separation on social behaviors in ovariectomized female mice.

Tsuda, M. C., & Ogawa, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0033028 · Cited by 86

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

No mediator is an island: A mediator supports others, but who supports the mediator?

Keys, B. (2006) · e-publications@bond (Bond University)

Transcriptional regulation of transcriptional Mediator complexes in cardiovascular development and disease.

Zhang, Y., Zhao, Y., Zhuang, L., et al. (2022) · PubMed · doi:10.16288/j.yczz.21-411

Suppression of p53 response by targeting p53-Mediator binding with a stapled peptidePreprint

Allen, B., Quach, K., Jones, T., Levandowski, C. B., Ebmeier, C. C., Rubin, J. D., Read, T. J., Dowell, R. D., Schepartz, A., & Taatjes, D. (2019) · bioRxiv · doi:10.1101/757401 · Cited by 10

Mediator: Structure and Function

Jin, L. (2005) · PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS