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The CRISPR-Cas immune system: Biology, mechanisms and applications

Rath, Devashish, Amlinger, Lina, Rath, Archana, Lundgren, Magnus·2015·Biochimie

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  • Cas gene codes for nuclease protein (Cas protein) responsible to destroy or cleave viral nucleic acid.

    “Cas gene is usually found adjacent to CRISPR that codes for nuclease protein (Cas protein) responsible to destroy or cleave viral nucleic acid.5”

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  1. Suttle, 2005, Viruses in the sea, Nature, 437, 356, 10.1038/nature04160 · DOI
  2. Barrangou, 2007, CRISPR provides acquired resistance against viruses in prokaryotes, Science, 315, 1709, 10.1126/science.1138140 · DOI · Paper page
  3. Jansen, 2002, Identification of a novel family of sequence repeats among prokaryotes, OMICS, 6, 23, 10.1089/15362310252780816 · DOI
  4. Hale, 2009, RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex, Cell, 139, 945, 10.1016/j.cell.2009.07.040 · DOI · Paper page
  5. Ishino, 1987, Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product, J. Bacteriol., 169, 5429, 10.1128/jb.169.12.5429-5433.1987 · DOI · Paper page
  6. Grissa, 2007, CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats, Nucleic Acids Res., 35, W52, 10.1093/nar/gkm360 · DOI
  7. Bolotin, 2005, Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin, Microbiology, 151, 2551, 10.1099/mic.0.28048-0 · DOI · Paper page
  8. Mojica, 2005, Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements, J. Mol. Evol., 60, 174, 10.1007/s00239-004-0046-3 · DOI · Paper page
  9. Pourcel, 2005, CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies, Microbiology, 151, 653, 10.1099/mic.0.27437-0 · DOI · Paper page
  10. Brouns, 2008, Small CRISPR RNAs guide antiviral defense in prokaryotes, Science, 321, 960, 10.1126/science.1159689 · DOI · Paper page
  11. Rousseau, 2009, CRISPI: a CRISPR interactive database, Bioinformatics, 25, 3317, 10.1093/bioinformatics/btp586 · DOI · Paper page
  12. Makarova, 2002, A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis, Nucleic Acids Res., 30, 482, 10.1093/nar/30.2.482 · DOI · Paper page
  13. Makarova, 2011, Evolution and classification of the CRISPR-Cas systems, Nat. Rev. Microbiol., 9, 467, 10.1038/nrmicro2577 · DOI · Paper page
  14. Koonin, 2014, Evolution of adaptive immunity from transposable elements combined with innate immune systems, Nat. Rev. Genet., 16, 184, 10.1038/nrg3859 · DOI
  15. Sinkunas, 2011, Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system, EMBO J., 30, 1335, 10.1038/emboj.2011.41 · DOI
  16. Garneau, 2010, The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA, Nature, 468, 67, 10.1038/nature09523 · DOI
  17. Wei, 2015, Cas9 function and host genome sampling in Type II-A CRISPR-Cas adaptation, Genes Dev., 29, 356, 10.1101/gad.257550.114 · DOI
  18. Heler, 2015, Cas9 specifies functional viral targets during CRISPR-Cas adaptation, Nature, 10.1038/nature14245 · DOI
  19. Koonin, 2013, CRISPR-Cas: evolution of an RNA-based adaptive immunity system in prokaryotes, RNA Biol., 10, 679, 10.4161/rna.24022 · DOI
  20. Chylinski, 2013, The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems, RNA Biol., 10, 726, 10.4161/rna.24321 · DOI · Paper page
  21. Rouillon, 2013, Structure of the CRISPR interference complex CSM reveals key similarities with cascade, Mol. Cell., 52, 124, 10.1016/j.molcel.2013.08.020 · DOI · Paper page
  22. Spilman, 2013, Structure of an RNA silencing complex of the CRISPR-Cas immune system, Mol. Cell., 52, 146, 10.1016/j.molcel.2013.09.008 · DOI
  23. Staals, 2013, Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus, Mol. Cell., 52, 135, 10.1016/j.molcel.2013.09.013 · DOI
  24. Pul, 2010, Identification and characterization of E. coli CRISPR-cas promoters and their silencing by H-NS, Mol. Microbiol., 75, 1495, 10.1111/j.1365-2958.2010.07073.x · DOI · Paper page
  25. Tyson, 2008, Rapidly evolving CRISPRs implicated in acquired resistance of microorganisms to viruses, Environ. Microbiol., 10, 200, 10.1111/j.1462-2920.2007.01444.x · DOI
  26. Andersson, 2008, Virus population dynamics and acquired virus resistance in natural microbial communities, Science, 320, 1047, 10.1126/science.1157358 · DOI
  27. Paez-Espino, 2013, Strong bias in the bacterial CRISPR elements that confer immunity to phage, Nat. Commun., 4, 1430, 10.1038/ncomms2440 · DOI
  28. Levin, 2013, The population and evolutionary dynamics of phage and bacteria with CRISPR-mediated immunity, PLoS Genet., 9, e1003312, 10.1371/journal.pgen.1003312 · DOI
  29. Nunez, 2015, Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity, Nature
  30. Erdmann, 2012, Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms, Mol. Microbiol., 85, 1044, 10.1111/j.1365-2958.2012.08171.x · DOI · Paper page
  31. Liu, 2015, Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition, Nucleic Acids Res., 10.1093/nar/gku1383 · DOI
  32. Li, 2014, Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process, Nucleic Acids Res., 42, 2483, 10.1093/nar/gkt1154 · DOI
  33. Swarts, 2012, CRISPR interference directs strand specific spacer acquisition, PLoS One, 7, e35888, 10.1371/journal.pone.0035888 · DOI
  34. Yosef, 2012, Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli, Nucleic Acids Res., 40, 5569, 10.1093/nar/gks216 · DOI · Paper page
  35. Datsenko, 2012, Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system, Nat. Commun., 3, 945, 10.1038/ncomms1937 · DOI · Paper page
  36. Cady, 2012, The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phages, J. Bacteriol., 194, 5728, 10.1128/JB.01184-12 · DOI
  37. Richter, 2014, Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer, Nucleic Acids Res., 42, 8516, 10.1093/nar/gku527 · DOI
  38. Wei, 2015, Sequences spanning the leader-repeat junction mediate CRISPR adaptation to phage in Streptococcus thermophilus, Nucleic Acids Res., 10.1093/nar/gku1407 · DOI
  39. Fineran, 2012, Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information, Virology, 434, 202, 10.1016/j.virol.2012.10.003 · DOI
  40. Babu, 2011, A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair, Mol. Microbiol., 79, 484, 10.1111/j.1365-2958.2010.07465.x · DOI · Paper page
  41. Wiedenheft, 2009, Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense, Structure, 17, 904, 10.1016/j.str.2009.03.019 · DOI · Paper page
  42. Beloglazova, 2008, A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats, J. Biol. Chem., 283, 20361, 10.1074/jbc.M803225200 · DOI
  43. Nunez, 2014, Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity, Nat. Struct. Mol. Biol., 21, 528, 10.1038/nsmb.2820 · DOI · Paper page
  44. Mojica, 2009, Short motif sequences determine the targets of the prokaryotic CRISPR defence system, Microbiology, 155, 733, 10.1099/mic.0.023960-0 · DOI · Paper page
  45. Dupuis, 2013, CRISPR-Cas and restriction-modification systems are compatible and increase phage resistance, Nat. Commun., 4, 2087, 10.1038/ncomms3087 · DOI
  46. Arslan, 2014, Detection and characterization of spacer integration intermediates in type I-E CRISPR-Cas system, Nucleic Acids Res., 42, 7884, 10.1093/nar/gku510 · DOI
  47. Fineran, 2014, Degenerate target sites mediate rapid primed CRISPR adaptation, Proc. Natl. Acad. Sci. U. S. A., 111, E1629, 10.1073/pnas.1400071111 · DOI
  48. Lillestol, 2009, CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties, Mol. Microbiol., 72, 259, 10.1111/j.1365-2958.2009.06641.x · DOI
  49. Hale, 2012, Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs, Mol. Cell., 45, 292, 10.1016/j.molcel.2011.10.023 · DOI
  50. Pougach, 2010, Transcription, processing and function of CRISPR cassettes in Escherichia coli, Mol. Microbiol., 77, 1367, 10.1111/j.1365-2958.2010.07265.x · DOI
  51. Carte, 2014, The three major types of CRISPR-Cas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus, Mol. Microbiol., 93, 98, 10.1111/mmi.12644 · DOI
  52. Nam, 2012, Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system, Structure, 20, 1574, 10.1016/j.str.2012.06.016 · DOI
  53. Jore, 2011, Structural basis for CRISPR RNA-guided DNA recognition by Cascade, Nat. Struct. Mol. Biol., 18, 529, 10.1038/nsmb.2019 · DOI
  54. Wiedenheft, 2011, Structures of the RNA-guided surveillance complex from a bacterial immune system, Nature, 477, 486, 10.1038/nature10402 · DOI
  55. Jackson, 2014, Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli, Science, 345, 1473, 10.1126/science.1256328 · DOI
  56. Mulepati, 2014, Structural biology. Crystal structure of a CRISPR RNA-guided surveillance complex bound to a ssDNA target, Science, 345, 1479, 10.1126/science.1256996 · DOI
  57. Zhao, 2014, Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli, Nature, 515, 147, 10.1038/nature13733 · DOI
  58. Beloglazova, 2015, CRISPR RNA binding and DNA target recognition by purified Cascade complexes from Escherichia coli, Nucleic Acids Res., 43, 530, 10.1093/nar/gku1285 · DOI
  59. Hatoum-Aslan, 2011, Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site, Proc. Natl. Acad. Sci. U. S. A., 108, 21218, 10.1073/pnas.1112832108 · DOI · Paper page
  60. Marraffini, 2008, CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA, Science, 322, 1843, 10.1126/science.1165771 · DOI · Paper page
  61. Zhang, 2012, Structure and mechanism of the CMR complex for CRISPR-mediated antiviral immunity, Mol. Cell., 45, 303, 10.1016/j.molcel.2011.12.013 · DOI
  62. Makarova, 2006, A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action, Biol. Direct, 1, 7, 10.1186/1745-6150-1-7 · DOI · Paper page
  63. Makarova, 2011, Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems, Biol. Direct, 6, 38, 10.1186/1745-6150-6-38 · DOI
  64. Westra, 2012, CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3, Mol. Cell., 46, 595, 10.1016/j.molcel.2012.03.018 · DOI
  65. Plagens, 2014, In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex, Nucleic Acids Res., 42, 5125, 10.1093/nar/gku120 · DOI
  66. Maier, 2013, Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B, RNA Biol., 10, 865, 10.4161/rna.24282 · DOI
  67. Semenova, 2011, Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence, Proc. Natl. Acad. Sci. U. S. A., 108, 10098, 10.1073/pnas.1104144108 · DOI · Paper page
  68. Wiedenheft, 2011, RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions, Proc. Natl. Acad. Sci. U. S. A., 108, 10092, 10.1073/pnas.1102716108 · DOI
  69. Sternberg, 2014, DNA interrogation by the CRISPR RNA-guided endonuclease Cas9, Nature, 507, 62, 10.1038/nature13011 · DOI · Paper page
  70. Sashital, 2012, Mechanism of foreign DNA selection in a bacterial adaptive immune system, Mol. Cell., 46, 606, 10.1016/j.molcel.2012.03.020 · DOI
  71. Hochstrasser, 2014, CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference, Proc. Natl. Acad. Sci. U. S. A., 111, 6618, 10.1073/pnas.1405079111 · DOI
  72. Zhu, 2014, Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complex, Nucleic Acids Res.
  73. Ramia, 2014, Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex, Cell. Rep., 9, 1610, 10.1016/j.celrep.2014.11.007 · DOI
  74. Benda, 2014, Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4, Mol. Cell., 56, 43, 10.1016/j.molcel.2014.09.002 · DOI
  75. Zebec, 2014, CRISPR-mediated targeted mRNA degradation in the archaeon Sulfolobus solfataricus, Nucleic Acids Res., 42, 5280, 10.1093/nar/gku161 · DOI
  76. Staals, 2014, RNA targeting by the Type III-A CRISPR-Cas Csm complex of Thermus thermophilus, Mol. Cell., 56, 518, 10.1016/j.molcel.2014.10.005 · DOI
  77. Tamulaitis, 2014, Programmable RNA Shredding by the Type III-A CRISPR-Cas system of Streptococcus thermophilus, Mol. Cell., 56, 506, 10.1016/j.molcel.2014.09.027 · DOI
  78. Deng, 2013, A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus, Mol. Microbiol., 87, 1088, 10.1111/mmi.12152 · DOI
  79. Peng, 2015, An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference, Nucleic Acids Res., 43, 406, 10.1093/nar/gku1302 · DOI
  80. Marraffini, 2010, Self versus non-self discrimination during CRISPR RNA-directed immunity, Nature, 463, 568, 10.1038/nature08703 · DOI
  81. Goldberg, 2014, Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting, Nature, 514, 633, 10.1038/nature13637 · DOI
  82. Deveau, 2008, Phage response to CRISPR-encoded resistance in Streptococcus thermophilus, J. Bacteriol., 190, 1390, 10.1128/JB.01412-07 · DOI
  83. Bondy-Denomy, 2013, Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system, Nature, 493, 429, 10.1038/nature11723 · DOI
  84. Pawluk, 2014, A new group of phage anti-CRISPR genes inhibits the type I-E CRISPR-Cas system of Pseudomonas aeruginosa, MBio, 5, e00896, 10.1128/mBio.00896-14 · DOI
  85. Seed, 2013, A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity, Nature, 494, 489, 10.1038/nature11927 · DOI
  86. Perez-Rodriguez, 2011, Envelope stress is a trigger of CRISPR RNA-mediated DNA silencing in Escherichia coli, Mol. Microbiol., 79, 584, 10.1111/j.1365-2958.2010.07482.x · DOI
  87. Mandin, 2007, Identification of new noncoding RNAs in Listeria monocytogenes and prediction of mRNA targets, Nucleic Acids Res., 35, 962, 10.1093/nar/gkl1096 · DOI
  88. Sampson, 2013, A CRISPR/Cas system mediates bacterial innate immune evasion and virulence, Nature, 497, 254, 10.1038/nature12048 · DOI
  89. Louwen, 2013, A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain-Barre syndrome, Eur. J. Clin. Microbiol. Infect. Dis., 32, 207, 10.1007/s10096-012-1733-4 · DOI
  90. Gunderson, 2013, The CRISPR-associated gene cas2 of Legionella pneumophila is required for intracellular infection of amoebae, MBio, 4, 10.1128/mBio.00074-13 · DOI
  91. Zegans, 2009, Interaction between bacteriophage DMS3 and host CRISPR region inhibits group behaviors of Pseudomonas aeruginosa, J. Bacteriol., 191, 210, 10.1128/JB.00797-08 · DOI
  92. Vercoe, 2013, Cytotoxic chromosomal targeting by CRISPR/Cas systems can reshape bacterial genomes and expel or remodel pathogenicity islands, PLoS Genet., 9, e1003454, 10.1371/journal.pgen.1003454 · DOI
  93. Groenen, 1993, Nature of DNA polymorphism in the direct repeat cluster of Mycobacterium tuberculosis; application for strain differentiation by a novel typing method, Mol. Microbiol., 10, 1057, 10.1111/j.1365-2958.1993.tb00976.x · DOI · Paper page
  94. Kamerbeek, 1997, Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology, J. Clin. Microbiol., 35, 907, 10.1128/JCM.35.4.907-914.1997 · DOI
  95. Cui, 2008, Insight into microevolution of Yersinia pestis by clustered regularly interspaced short palindromic repeats, PLoS One, 3, e2652, 10.1371/journal.pone.0002652 · DOI
  96. Liu, 2011, Subtyping Salmonella enterica serovar enteritidis isolates from different sources by using sequence typing based on virulence genes and clustered regularly interspaced short palindromic repeats (CRISPRs), Appl. Environ. Microbiol., 77, 4520, 10.1128/AEM.00468-11 · DOI
  97. Liu, 2011, Novel virulence gene and clustered regularly interspaced short palindromic repeat (CRISPR) multilocus sequence typing scheme for subtyping of the major serovars of Salmonella enterica subsp. enterica, Appl. Environ. Microbiol., 77, 1946, 10.1128/AEM.02625-10 · DOI
  98. Mokrousov, 2005, Efficient discrimination within a Corynebacterium diphtheriae epidemic clonal group by a novel macroarray-based method, J. Clin. Microbiol., 43, 1662, 10.1128/JCM.43.4.1662-1668.2005 · DOI
  99. Wood, 2011, Targeted genome editing across species using ZFNs and TALENs, Science, 333, 307, 10.1126/science.1207773 · DOI
  100. Terns, 2014, CRISPR-based technologies: prokaryotic defense weapons repurposed, Trends Genet., 30, 111, 10.1016/j.tig.2014.01.003 · DOI
  101. Wang, 2014, Genetic screens in human cells using the CRISPR-Cas9 system, Science, 343, 80, 10.1126/science.1246981 · DOI · Paper page
  102. O'Connell, 2014, Programmable RNA recognition and cleavage by CRISPR/Cas9, Nature, 516, 263, 10.1038/nature13769 · DOI
  103. Bikard, 2014, Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials, Nat. Biotechnol., 32, 1146, 10.1038/nbt.3043 · DOI · Paper page
  104. Citorik, 2014, Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases, Nat. Biotechnol., 32, 1141, 10.1038/nbt.3011 · DOI · Paper page
  105. Long, 2014, Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA, Science, 345, 1184, 10.1126/science.1254445 · DOI · Paper page
  106. Yin, 2014, Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype, Nat. Biotechnol., 32, 551, 10.1038/nbt.2884 · DOI · Paper page
  107. Hu, 2014, RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection, Proc. Natl. Acad. Sci. U. S. A., 111, 11461, 10.1073/pnas.1405186111 · DOI · Paper page
  108. Ye, 2014, Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Delta32 mutation confers resistance to HIV infection, Proc. Natl. Acad. Sci. U. S. A., 111, 9591, 10.1073/pnas.1407473111 · DOI · Paper page
  109. Zhen, 2015, Harnessing the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated Cas9 system to disrupt the hepatitis B virus, Gene Ther., 10.1038/gt.2015.2 · DOI · Paper page
  110. Niu, 2014, Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos, Cell, 156, 836, 10.1016/j.cell.2014.01.027 · DOI · Paper page
  111. Rath, 2015, Efficient programmable gene silencing by Cascade, Nucleic Acids Res., 43, 237, 10.1093/nar/gku1257 · DOI
  112. Luo, 2015, Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression, Nucleic Acids Res., 43, 674, 10.1093/nar/gku971 · DOI
  113. Bikard, 2013, Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system, Nucleic Acids Res., 41, 7429, 10.1093/nar/gkt520 · DOI · Paper page
  114. Cheng, 2013, Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system, Cell. Res., 23, 1163, 10.1038/cr.2013.122 · DOI
  115. Farzadfard, 2013, Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas, ACS Synth. Biol., 2, 604, 10.1021/sb400081r · DOI
  116. Levy, 2015, CRISPR adaptation biases explain preference for acquisition of foreign DNA, Nature, 10.1038/nature14302 · DOI

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Metadata

Authors
Rath, D., Amlinger, L., Rath, A., & Lundgren, M.
Venue
Biochimie
Publisher
Elsevier BV
Published
2015-10
Volume
117
Pages
119-128
ISSN
0300-9084
Cited by
471
References
15
Language
en
Funders
  • Uppsala University
  • Swedish Research Council
  • Bhabha Atomic Research Center
  • University of Mumbai
  • Wenner-Gren Foundations

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