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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
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SpCas9 can recognize a 5′-NGG protospacer adjacent motif (PAM), which is part of the non-self-sequence recognized by the CRISPR bacterial adaptive immune system.
“SpCas9 can recognize a 5′-NGG protospacer adjacent motif (PAM), which is part of the non-self-sequence recognized by the CRISPR bacterial adaptive immune system.”
From Viral Delivery Systems for CRISPR (2019) · cites this paper as [66]
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Metadata
- Authors
- Sternberg, S. H., Redding, S., Jinek, M., Greene, E. C., & Doudna, J. A.
- Venue
- Nature
- Published
- 2014-01-29
- Volume
- 507
- Issue
- 7490
- Pages
- 62-67
- ISSN
- 0028-0836
- 1476-4687
- PMC
- PMC4106473
- Cited by
- 1,822
- References
- 16
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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