Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs

Fiji: an open-source platform for biological-image analysis

Schindelin, J., Arganda-Carreras, I., Frise, E., Kaynig, V., Longair, M., Pietzsch, T., Preibisch, S., Rueden, C., Saalfeld, S., Schmid, B., et al. (2012) · Nature Methods · doi:10.1038/nmeth.2019 · Cited by 66,890

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Fontenot, J. D., Gavin, M. A., & Rudensky, A. Y. (2003) · Nature Immunology · doi:10.1038/ni904 · Cited by 7,745

N aturally A rising CD4+R egulatory T C ells for I mmunologic S elf-T olerance and N egative C ontrol of I mmune R esponses

Sakaguchi, S. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141122 · Cited by 3,306

Regulatory T cells: mechanisms of differentiation and function

Josefowicz, S. Z., Lu, L.-F., & Rudensky, A. Y. (2012) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141623 · Cited by 2,866

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A., Paeper, B., Clark, L. B., Yasayko, S.-A., Wilkinson, J. E., Galas, D., Ziegler, S. F., & Ramsdell, F. (2001) · Nature Genetics · doi:10.1038/83784 · Cited by 2,636

Transient Regenerative Potential of the Neonatal Mouse Heart

Porrello, E. R., Mahmoud, A. I., Simpson, E., Hill, J. A., Richardson, J. A., Olson, E. N., & Sadek, H. A. (2011) · Science · doi:10.1126/science.1200708 · Cited by 2,545

FOXP3+ regulatory T cells in the human immune system

Sakaguchi, S., Miyara, M., Costantino, C. M., & Hafler, D. A. (2010) · Nature Reviews Immunology · doi:10.1038/nri2785 · Cited by 2,439

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Fontenot, J. D., Rasmussen, J. P., Williams, L. M., Dooley, J. L., Farr, A. G., & Rudensky, A. Y. (2005) · Immunity · doi:10.1016/j.immuni.2005.01.016 · Cited by 2,279

Heart Regeneration in Zebrafish

Poss, K. D., Wilson, L. G., & Keating, M. T. (2002) · Science · doi:10.1126/science.1077857 · Cited by 1,932

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

Thornton, A. M., Korty, P. E., Tran, D. Q., Wohlfert, E. A., Murray, P. E., Belkaid, Y., & Shevach, E. M. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0904028 · Cited by 1,382

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

Jopling, C., Sleep, E., Raya, M., Martí, M., Raya, A., & Belmonte, J. C. I. (2010) · Nature · doi:10.1038/nature08899 · Cited by 1,333

A Special Population of Regulatory T Cells Potentiates Muscle Repair

Burzyn, D., Kuswanto, W., Kolodin, D., Shadrach, J. L., Cerletti, M., Jang, Y., Sefik, E., Tan, T. G., Wagers, A. J., Benoist, C., et al. (2013) · Cell · doi:10.1016/j.cell.2013.10.054 · Cited by 1,234

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

Cipolletta, D., Feuerer, M., Li, A., Kamei, N., Lee, J., Shoelson, S. E., Benoist, C., & Mathis, D. (2012) · Nature · doi:10.1038/nature11132 · Cited by 1,143

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

Liesz, A., Suri-Payer, E., Veltkamp, C., Doerr, H., Sommer, C., Rivest, S., Giese, T., & Veltkamp, R. (2009) · Nature Medicine · doi:10.1038/nm.1927 · Cited by 1,115

Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes

Kikuchi, K., Holdway, J. E., Werdich, A. A., Anderson, R. M., Fang, Y., Egnaczyk, G. F., Evans, T., MacRae, C. A., Stainier, D. Y. R., & Poss, K. D. (2010) · Nature · doi:10.1038/nature08804 · Cited by 1,054

T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse

Moran, A. E., Holzapfel, K. L., Xing, Y., Cunningham, N. R., Maltzman, J. S., Punt, J., & Hogquist, K. A. (2011) · Journal of Experimental Medicine · doi:10.1084/jem.20110308 · Cited by 1,034

Neuregulin1/ErbB4 Signaling Induces Cardiomyocyte Proliferation and Repair of Heart Injury

Bersell, K., Arab, S., Haring, B., & Kühn, B. (2009) · Cell · doi:10.1016/j.cell.2009.04.060 · Cited by 1,032

A Distinct Function of Regulatory T Cells in Tissue Protection

Arpaia, N., Green, J. A., Moltedo, B., Arvey, A., Hemmers, S., Yuan, S., Treuting, P. M., & Rudensky, A. Y. (2015) · Cell · doi:10.1016/j.cell.2015.08.021 · Cited by 991

Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants

Traver, D., Paw, B. H., Poss, K. D., Penberthy, W. T., Lin, S., & Zon, L. I. (2003) · Nature Immunology · doi:10.1038/ni1007 · Cited by 800

Foxp3+CD4+T Cells Improve Healing After Myocardial Infarction by Modulating Monocyte/Macrophage Differentiation

Weirather, J., Hofmann, U. D. W., Beyersdorf, N., Ramos, G. C., Vogel, B., Frey, A., Ertl, G., Kerkau, T., & Frantz, S. (2014) · Circulation Research · doi:10.1161/circresaha.115.303895 · Cited by 699

Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation

Ali, N., Zirak, B., Rodriguez, R. S., Pauli, M. L., Truong, H.-A., Lai, K., Ahn, R., Corbin, K., Lowe, M. M., Scharschmidt, T. C., et al. (2017) · Cell · doi:10.1016/j.cell.2017.05.002 · Cited by 680

ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation

D’Uva, G., Aharonov, A., Lauriola, M., Kain, D., Yahalom-Ronen, Y., Carvalho, S., Weisinger, K., Bassat, E., Rajchman, D., Yifa, O., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3149 · Cited by 657

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

Yadav, M., Louvet, C., Davini, D., Gardner, J. M., Martinez-Llordella, M., Bailey-Bucktrout, S., Anthony, B. A., Sverdrup, F. M., Head, R., Kuster, D. J., et al. (2012) · Journal of Experimental Medicine · doi:10.1084/jem.20120822 · Cited by 649

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

Weiss, J. M., Bilate, A. M., Gobert, M., Ding, Y., Curotto de Lafaille, M. A., Parkhurst, C. N., Xiong, H., Dolpady, J., Frey, A. B., Ruocco, M. G., et al. (2012) · Journal of Experimental Medicine · doi:10.1084/jem.20120914 · Cited by 621

The Use of Zebrafish to Understand Immunity

Trede, N. S., Langenau, D. M., Traver, D., Look, A. T., & Zon, L. I. (2004) · Immunity · doi:10.1016/s1074-7613(04)00084-6 · Cited by 603

Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells

Bosurgi, L., Cao, Y. G., Cabeza-Cabrerizo, M., Tucci, A., Hughes, L. D., Kong, Y., Weinstein, J. S., Licona-Limon, P., Schmid, E. T., Pelorosso, F., et al. (2017) · Science · doi:10.1126/science.aai8132 · Cited by 560

Regulatory T cells promote myelin regeneration in the central nervous system

Dombrowski, Y., O'Hagan, T., Dittmer, M., Penalva, R., Mayoral, S. R., Bankhead, P., Fleville, S., Eleftheriadis, G., Zhao, C., Naughton, M., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4528 · Cited by 533

Acute Inflammation Initiates the Regenerative Response in the Adult Zebrafish Brain

Kyritsis, N., Kizil, C., Zocher, S., Kroehne, V., Kaslin, J., Freudenreich, D., Iltzsche, A., & Brand, M. (2012) · Science · doi:10.1126/science.1228773 · Cited by 517

Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells

Kuswanto, W., Burzyn, D., Panduro, M., Wang, K. K., Jang, Y. C., Wagers, A. J., Benoist, C., & Mathis, D. (2016) · Immunity · doi:10.1016/j.immuni.2016.01.009 · Cited by 517

Conditional targeted cell ablation in zebrafish: A new tool for regeneration studies

Curado, S., Anderson, R. M., Jungblut, B., Mumm, J., Schroeter, E., & Stainier, D. Y. R. (2007) · Developmental Dynamics · doi:10.1002/dvdy.21100 · Cited by 507

Activation of CD4 + T Lymphocytes Improves Wound Healing and Survival After Experimental Myocardial Infarction in Mice

Hofmann, U., Beyersdorf, N., Weirather, J., Podolskaya, A., Bauersachs, J., Ertl, G., Kerkau, T., & Frantz, S. (2012) · Circulation · doi:10.1161/circulationaha.111.044164 · Cited by 471

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish

González-Rosa, J. M., Martín, V., Peralta, M., Torres, M., & Mercader, N. (2011) · Development · doi:10.1242/dev.060897 · Cited by 468

Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors

Kroehne, V., Freudenreich, D., Hans, S., Kaslin, J., & Brand, M. (2011) · Development · doi:10.1242/dev.072587 · Cited by 452

A Role for 1 Tubulin-Expressing Muller Glia in Regeneration of the Injured Zebrafish Retina

Fausett, B. V., & Goldman, D. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0332-06.2006 · Cited by 435

In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish

Langenau, D. M., Ferrando, A. A., Traver, D., Kutok, J. L., Hezel, J.-P. D., Kanki, J. P., Zon, L. I., Look, A. T., & Trede, N. S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402248101 · Cited by 429

Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing

Nosbaum, A., Prevel, N., Truong, H.-A., Mehta, P., Ettinger, M., Scharschmidt, T. C., Ali, N. H., Pauli, M. L., Abbas, A. K., & Rosenblum, M. D. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1502139 · Cited by 418

The zebrafish heart regenerates after cryoinjury-induced myocardial infarction

Chablais, F., Veit, J., Rainer, G., & Jaźwińska, A. (2011) · BMC Developmental Biology · doi:10.1186/1471-213x-11-21 · Cited by 418

Axonal regrowth after spinal cord transection in adult zebrafish

Becker, T., Wullimann, M. F., Becker, C. G., Bernhardt, R. R., & Schachner, M. (1997) · Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970127)377:4<577::aid-cne8>3.0.co;2-# · Cited by 408

Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase

Pisharath, H., Rhee, J. M., Swanson, M. A., Leach, S. D., & Parsons, M. J. (2007) · Mechanisms of Development · doi:10.1016/j.mod.2006.11.005 · Cited by 373

GFAP transgenic zebrafish

Bernardos, R. L., & Raymond, P. A. (2006) · Gene Expression Patterns · doi:10.1016/j.modgep.2006.04.006 · Cited by 373

Macrophages modulate adult zebrafish tail fin regeneration

Petrie, T. A., Strand, N. S., Tsung-Yang, C., Rabinowitz, J. S., & Moon, R. T. (2014) · Development · doi:10.1242/dev.098459 · Cited by 365

Live imaging reveals differing roles of macrophages and neutrophils during zebrafish tail fin regeneration

Li, L., Yan, B., Shi, Y.-Q., Zhang, W.-Q., & Wen, Z.-L. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.349126 · Cited by 353

High-throughput assay for small molecules that modulate zebrafish embryonic heart rate

Burns, C. G., Milan, D. J., Grande, E. J., Rottbauer, W., MacRae, C. A., & Fishman, M. C. (2005) · Nature Chemical Biology · doi:10.1038/nchembio732 · Cited by 327

Regulatory T cells ameliorate cardiac remodeling after myocardial infarction

Tang, T.-T., Yuan, J., Zhu, Z.-F., Zhang, W.-C., Xiao, H., Xia, N., Yan, X.-X., Nie, S.-F., Liu, J., Zhou, S.-F., et al. (2012) · Basic Research in Cardiology · doi:10.1007/s00395-011-0232-6 · Cited by 318

Immune Modulation of Stem Cells and Regeneration

Aurora, A. B., & Olson, E. N. (2014) · Cell Stem Cell · doi:10.1016/j.stem.2014.06.009 · Cited by 308

Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish

Gemberling, M., Karra, R., Dickson, A. L., & Poss, K. D. (2015) · eLife · doi:10.7554/elife.05871 · Cited by 302

Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration

Lai, S.-L., Marín-Juez, R., Moura, P. L., Kuenne, C., Lai, J. K. H., Tsedeke, A. T., Guenther, S., Looso, M., & Stainier, D. Y. (2017) · eLife · doi:10.7554/elife.25605 · Cited by 289

Regeneration of Cryoinjury Induced Necrotic Heart Lesions in Zebrafish Is Associated with Epicardial Activation and Cardiomyocyte Proliferation

Schnabel, K., Wu, C.-C., Kurth, T., & Weidinger, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018503 · Cited by 279

Motor Neuron Regeneration in Adult Zebrafish

Reimer, M. M., Sörensen, I., Kuscha, V., Frank, R. E., Liu, C., Becker, C. G., & Becker, T. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1189-08.2008 · Cited by 276

Fgf-Dependent Glial Cell Bridges Facilitate Spinal Cord Regeneration in Zebrafish

Goldshmit, Y., Sztal, T. E., Jusuf, P. R., Hall, T. E., Nguyen-Chi, M., & Currie, P. D. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0758-12.2012 · Cited by 274

Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window

Polizzotti, B. D., Ganapathy, B., Walsh, S., Choudhury, S., Ammanamanchi, N., Bennett, D. G., dos Remedios, C. G., Haubner, B. J., Penninger, J. M., & Kühn, B. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa5171 · Cited by 225

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

Beyer, M., Thabet, Y., Müller, R.-U., Sadlon, T., Classen, S., Lahl, K., Basu, S., Zhou, X., Bailey-Bucktrout, S. L., Krebs, W., et al. (2011) · Nature Immunology · doi:10.1038/ni.2084 · Cited by 212

NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis

Shimazu, K., Zhao, M., Sakata, K., Akbarian, S., Bates, B., Jaenisch, R., & Lu, B. (2006) · Learning & Memory · doi:10.1101/lm.76006 · Cited by 200

Local amplifiers of IL-4Rα–mediated macrophage activation promote repair in lung and liver

Minutti, C. M., Jackson-Jones, L. H., García-Fojeda, B., Knipper, J. A., Sutherland, T. E., Logan, N., Ringqvist, E., Guillamat-Prats, R., Ferenbach, D. A., Artigas, A., et al. (2017) · Science · doi:10.1126/science.aaj2067 · Cited by 194

Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration

Fang, Y., Gupta, V., Karra, R., Holdway, J. E., Kikuchi, K., & Poss, K. D. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1309810110 · Cited by 193

Regenerative Capacity and the Developing Immune System

Mescher, A. L., & Neff, A. W. (2005) · Advances in Biochemical Engineering/Biotechnology · doi:10.1007/b99966 · Cited by 185

Live imaging of adult neural stem cell behavior in the intact and injured zebrafish brain

Barbosa, J. S., Sanchez-Gonzalez, R., Di Giaimo, R., Baumgart, E. V., Theis, F. J., Götz, M., & Ninkovic, J. (2015) · Science · doi:10.1126/science.aaa2729 · Cited by 184

Endothelial NT-3 Delivered by Vasculature and CSF Promotes Quiescence of Subependymal Neural Stem Cells through Nitric Oxide Induction

Delgado, A. C., Ferrón, S. R., Vicente, D., Porlan, E., Perez-Villalba, A., Trujillo, C. M., D′Ocón, P., & Fariñas, I. (2014) · Neuron · doi:10.1016/j.neuron.2014.06.015 · Cited by 182

FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration

Castiglioni, A., Corna, G., Rigamonti, E., Basso, V., Vezzoli, M., Monno, A., Almada, A. E., Mondino, A., Wagers, A. J., Manfredi, A. A., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0128094 · Cited by 170

Inhibition of Müller glial cell division blocks regeneration of the light‐damaged zebrafish retina

Thummel, R., Kassen, S. C., Montgomery, J. E., Enright, J. M., & Hyde, D. R. (2008) · Developmental Neurobiology · doi:10.1002/dneu.20596 · Cited by 168

CNS Repair Requires Both Effector and Regulatory T Cells with Distinct Temporal and Spatial Profiles

Raposo, C., Graubardt, N., Cohen, M., Eitan, C., London, A., Berkutzki, T., & Schwartz, M. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0076-14.2014 · Cited by 161

Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold

Hasegawa, T., Hall, C. J., Crosier, P. S., Abe, G., Kawakami, K., Kudō, A., & Kawakami, A. (2017) · eLife · doi:10.7554/elife.22716 · Cited by 154

Genome-Wide Identification of Human FOXP3 Target Genes in Natural Regulatory T Cells

Sadlon, T. J., Wilkinson, B. G., Pederson, S., Brown, C. Y., Bresatz, S., Gargett, T., Melville, E. L., Peng, K., D’Andrea, R. J., Glonek, G. G., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000082 · Cited by 146

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes

Dee, C., Nagaraju, R. T., Athanasiadis, E. I., Gray, C., del Ama, L. F., Johnston, S. A., Secombes, C. J., Cvejic, A., & Hurlstone, A. F. L. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1600959 · Cited by 145

Retinal injury, growth factors, and cytokines converge on β-catenin and pStat3 signaling to stimulate retina regeneration

Wan, J., Zhao, X.-F., Vojtek, A., & Goldman, D. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.048 · Cited by 143

Suppression of the immune response potentiates tadpole tail regeneration during the refractory period

Fukazawa, T., Naora, Y., Kunieda, T., & Kubo, T. (2009) · Development · doi:10.1242/dev.033985 · Cited by 115

Exogenous Growth Factors Stimulate the Regeneration of Ganglion Cells in the Chicken Retina

Fischer, A. J., & Reh, T. A. (2002) · Developmental Biology · doi:10.1006/dbio.2002.0813 · Cited by 115

Treatment of Glucocorticoids Inhibited Early Immune Responses and Impaired Cardiac Repair in Adult Zebrafish

Huang, W., Yang, C., Chen, I.-H., Liu, Y.-M. L., Chang, S., & Chuang, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066613 · Cited by 108

Immunization with a Myelin-Derived Antigen Activates the Brain's Choroid Plexus for Recruitment of Immunoregulatory Cells to the CNS and Attenuates Disease Progression in a Mouse Model of ALS

Kunis, G., Baruch, K., Miller, O., & Schwartz, M. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3644-14.2015 · Cited by 105

Distinct effects of inflammation on preconditioning and regeneration of the adult zebrafish heart

Charles, A.-S. D. P., Bise, T., Baier, F. A., Marro, J., & Jaźwińska, A. (2016) · Open Biology · doi:10.1098/rsob.160102 · Cited by 96

Regulatory T Cells in Central Nervous System Injury: A Double-Edged Sword

Walsh, J. T., Zheng, J., Smirnov, I., Lorenz, U. M., Tung, K. S. K., & Kipnis, J. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1302401 · Cited by 91

Adaptive Autoimmunity and Foxp3-Based Immunoregulation in Zebrafish

Quintana, F. J., Iglesias, A. H., Farez, M., Cáccamo, M., Burns, E. J., Kassam, N., Oukka, M., & Weiner, H. L. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009478 · Cited by 89

Identification and characterization of the transcription factors involved in T‐cell development, t‐bet, stat6 and foxp3, within the zebrafish, Danio rerio

Mitra, S., Alnabulsi, A., Secombes, C. J., & Bird, S. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07460.x · Cited by 83

The combination of IGF1 and FGF2 and the induction of excessive ocular growth and extreme myopia

Ritchey, E. R., Zelinka, C. P., Tang, J., Liu, J., & Fischer, A. J. (2012) · Experimental Eye Research · doi:10.1016/j.exer.2012.03.019 · Cited by 71

An Element in the α1-Tubulin Promoter Is Necessary for Retinal Expression during Optic Nerve Regeneration But Not after Eye Injury in the Adult Zebrafish

Senut, M., Gulati-Leekha, A., & Goldman, D. J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2281-04.2004 · Cited by 71

Efficient transposition of the Tol2 transposable element from a single-copy donor in zebrafish

Urasaki, A., Asakawa, K., & Kawakami, K. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810380105 · Cited by 71

Zebrafish FOXP3 is required for the maintenance of immune tolerance

Sugimoto, K., Hui, S. P., Sheng, D. Z., Nakayama, M., & Kikuchi, K. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.03.023 · Cited by 69

Comparative Genomics Reveals Key Gain-of-Function Events in Foxp3 during Regulatory T Cell Evolution

Andersen, K. G., Nissen, J. K., & Betz, A. G. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00113 · Cited by 67

Characterization of Proliferating Neural Progenitors after Spinal Cord Injury in Adult Zebrafish

Hui, S. P., Nag, T. C., & Ghosh, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0143595 · Cited by 67

Macrophages modulate adult zebrafish tail fin regeneration

Petrie, T. A., Strand, N. S., Yang, C.-T., Rabinowitz, J. S., & Moon, R. T. (2015) · Development · doi:10.1242/dev.120642 · Cited by 41

Regulatory T cells in autoimmune disease

Dominguez-Villar, M., & Hafler, D. A. (2018) · Nature Immunology · doi:10.1038/s41590-018-0120-4 · Cited by 713

Principles of regulatory T cell function

Dikiy, S., & Rudensky, A. Y. (2023) · Immunity · doi:10.1016/j.immuni.2023.01.004 · Cited by 445

A cold-blooded view of adaptive immunity

Flajnik, M. F. (2018) · Nature Reviews Immunology · doi:10.1038/s41577-018-0003-9 · Cited by 348

Tissue regulatory T cells: regulatory chameleons

Muñoz-Rojas, A. R., & Mathis, D. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00519-w · Cited by 281

Comparative regenerative mechanisms across different mammalian tissues

Iismaa, S. E., Kaidonis, X., Nicks, A. M., Bogush, N., Kikuchi, K., Naqvi, N., Harvey, R. P., Husain, A., & Graham, R. M. (2018) · npj Regenerative Medicine · doi:10.1038/s41536-018-0044-5 · Cited by 253