Cited by 111Autism Spectrum Disorder ResearchAttention Deficit Hyperactivity DisorderChild and Adolescent Psychosocial and Emotional Development

Changing ASD-ADHD symptom co-occurrence across the lifespan with adolescence as crucial time window: Illustrating the need to go beyond childhood

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Hartman, Catharina A., Geurts, Hilde M., Franke, Barbara, Buitelaar, Jan K., Rommelse, Nanda N.J.·2016·Neuroscience & Biobehavioral Reviews

Abstract

Literature on the co-occurrence between Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) is strongly biased by a focus on childhood age. A review of the adolescent and adult literature was made on core and related symptoms of ADHD and ASD. In addition, an empirical approach was used including 17,173 ASD-ADHD symptom ratings from participants aged 0 to 84 years. Results indicate that ASD/ADHD constellations peak during adolescence and are lower in early childhood and old age. We hypothesize that on the border of the expected transition to independent adulthood, ASD and ADHD co-occur most because social adaptation and EF skills matter most. Lower correlations in childhood and older age may be due to more diffuse symptoms reflecting respectively still differentiating and de-differentiating EF functions. We plea for a strong research focus in adolescence which may -after early childhood- be a second crucial time window for catching-up pattern explaining more optimal outcomes. We discuss obstacles and oppportunities of a full lifespan approach into old age.

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Crossref · 10.1016/j.neubiorev.2016.09.003

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  1. APA, 2000. Diagnostic and Statistical Manual of Disorders, Fourth Edition, Text Revision. American Psychiatric Association, Washington DC.

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Authors
Hartman, C. A., Geurts, H. M., Franke, B., Buitelaar, J. K., & Rommelse, N. N. J.
Affiliations
  • University Medical Center Groningen (NL)
  • University of Amsterdam (NL)
  • Radboud University Nijmegen (NL)
  • Radboud University Medical Center (NL)
Corresponding author
Hartman, Catharina A.
Venue
Neuroscience & Biobehavioral Reviews
Publisher
Elsevier BV
Published
2016-12
Volume
71
Pages
529-541
ISSN
0149-7634 (ISSN-L)
OpenAlex
W2519963735
Cited by
111
References
196
Citations by year
2026: 4 · 2025: 15 · 2024: 15 · 2023: 15 · 2022: 11 · 2021: 9 · 2020: 10 · 2019: 11 · 2018: 13 · 2017: 7 · 2016: 1
FWCI
1.13
Type
journal article
Language
en
Open access
Locations
  • Neuroscience & Biobehavioral Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
  • Radboud Repository (Radboud University) (submittedVersion)
  • UvA-DARE (University of Amsterdam) (submittedVersion, other-oa)
  • University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords
autism spectrum disorder, attention deficit hyperactivity disorder, lifespan development, adolescence, executive function, social adaptation, catching up
MeSH terms
Autism Spectrum Disorder, Adolescent, Attention Deficit Disorder with Hyperactivity, Humans, Comorbidity

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