Cited by 506Neuroendocrine regulation and behaviorNeuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

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Neuromodulation by Oxytocin and Vasopressin

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Stoop, Ron·2012·Neuron

DOI 10.1016/j.neuron.2012.09.025

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Abstract

Oxytocin (OT) and vasopressin (VP) are two closely related neuropeptides, widely known for their peripheral hormonal effects. Specific receptors have also been found in the brain, where their neuromodulatory actions have meanwhile been described in a large number of regions. Recently, it has become possible to study their endogenous neuropeptide release with the help of OT/VP promoter-driven expression of fluorescent proteins and light-activated ion channels. In this review, I summarize the neuromodulatory effects of OT and VP in different brain regions by grouping these into different behavioral systems, highlighting their concerted, and at times opposite, effects on different aspects of behavior.

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Authors: Stoop, R.
Affiliations: Centre Hospitalier Universitaire Vaudois (CH)
Corresponding author: Stoop, Ron
ORCID: Stoop, Ron
Venue: Neuron
Publisher: Elsevier BV
Published: 2012-10
Volume: 76
Issue: 1
Pages: 142-159
ISSN: 0896-6273 (ISSN-L)
DOI: 10.1016/j.neuron.2012.09.025
OpenAlex: W2045659750
Cited by: 506
References: 155
Citations by year: 2026: 26 · 2025: 18 · 2024: 20 · 2023: 24 · 2022: 33 · 2021: 47 · 2020: 64 · 2019: 38 · 2018: 47 · 2017: 46 · 2016: 39 · 2015: 31 · 2014: 38 · 2013: 35
FWCI: 4.71
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 368 d)
Locations: Neuron (publishedVersion)
PubMed (publishedVersion)
IRIS (submittedVersion)
SERVAL (Université de Lausanne) (submittedVersion)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: oxytocin, vasopressin, neuromodulation, neuropeptide receptors, brain regions, behavior, fluorescent protein reporter, light-activated ion channels
MeSH terms: Animals, Brain, Humans, Oxytocin, Vasopressins, Neurotransmitter Agents

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Neuromodulation by Oxytocin and Vasopressin

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