CORONARY HEART-DISEASE AND PHYSICAL ACTIVITY OF WORK

Morris, J.N., Heady, J.A., Raffle, P.A.B., Roberts, C.G., Parks, J.W.·1953·The Lancet

DOI 10.1016/s0140-6736(53)90665-5

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McConnell, M. V., Shcherbina, A., Pavlovic, A., Homburger, J. R., Goldfeder, R. L., Waggot, D., Cho, M. K., Rosenberger, M. E., Haskell, W. L., Myers, J., et al. (2017) · JAMA Cardiology · doi:10.1001/jamacardio.2016.4395 · Cited by 239
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Bennie, J. A., De Cocker, K., Teychenne, M. J., Brown, W. J., & Biddle, S. J. H. (2019) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/s12966-019-0797-2 · Cited by 224
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Haskell, W. L. (2012) · Journal of Physical Activity and Health · doi:10.1123/jpah.9.s1.s5 · Cited by 221
Exercise, Vascular Wall and Cardiovascular Diseases: An Update (Part 1)
Leung, F. P., Yung, L. M., Laher, I., Yao, X., Chen, Z. Y., & Huang, Y. (2008) · Sports Medicine · doi:10.2165/00007256-200838120-00005 · Cited by 219
Abdominal obesity: The most prevalent cause of the metabolic syndrome and related cardiometabolic risk
Després, J.-P. (2006) · European Heart Journal Supplements · doi:10.1093/eurheartj/sul002 · Cited by 205
Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome
Paniagua, J. A. (2016) · World Journal of Diabetes · doi:10.4239/wjd.v7.i19.483 · Cited by 197
Childhood physical fitness tests: predictor of adult physical activity levels?
Dennison, B. A., Straus, J. H., Mellits, E. D., & Charney, E. (1988) · PEDIATRICS · doi:10.1542/peds.82.3.324 · Cited by 190
Sedentary behavior: Understanding and influencing adults' prolonged sitting time
Owen, N. (2012) · Preventive Medicine · doi:10.1016/j.ypmed.2012.08.024 · Cited by 187
Assessment of physical activity and energy expenditure in epidemiological research of chronic diseases
Lagerros, Y. T., & Lagiou, P. (2007) · European Journal of Epidemiology · doi:10.1007/s10654-007-9154-x · Cited by 178
Role of Interleukin-6 in Vascular Health and Disease
Villar-Fincheira, P., Sanhueza-Olivares, F., Norambuena-Soto, I., Cancino-Arenas, N., Hernandez-Vargas, F., Troncoso, R., Gabrielli, L., & Chiong, M. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2021.641734 · Cited by 154
Physical Activity and Fitness for Health and Longevity
Paffenbarger, R. S., & Lee, I.-M. (1996) · Research Quarterly for Exercise and Sport · doi:10.1080/02701367.1996.10608850 · Cited by 147
Physical activity, physical fitness and longevity
Lee, I. M., Paffenbarger, R. S., & Hennekens, C. H. (1997) · Aging Clinical and Experimental Research · doi:10.1007/bf03340123 · Cited by 146
The effects of endurance exercise on the heart: panacea or poison?
Parry-Williams, G., & Sharma, S. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0354-3 · Cited by 102
Physical activity counseling in primary care: Insights from public health and behavioral economics
Shuval, K., Leonard, T., Drope, J., Katz, D. L., Patel, A. V., Maitin‐Shepard, M., Amir, O., & Grinstein, A. (2017) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21394 · Cited by 91
Is physical activity a cause of longevity? It is not as straightforward as some would believe. A critical analysis
Kujala, U. M. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-098639 · Cited by 83
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Ozemek, C., Cochran, H. L., Strath, S. J., Byun, W., & Kaminsky, L. A. (2013) · BMC Medical Research Methodology · doi:10.1186/1471-2288-13-53 · Cited by 69
“In large scale epidemiologic studies, the absolute method of classifying PA has been used to establish associations between PA habits and various health outcomes, such as cardiovascular disease [5,6].”
Cardiorespiratory fitness and health outcomes: a call to standardize fitness categories.
Kokkinos, P., Myers, J., Franklin, B., Narayan, P., Lavie, C. J., & Faselis, C. (2018) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2017.10.011 · Cited by 65
Exercise and sports participation in patients with thoracic aortic disease: a review
Thijssen, C. G. E., Bons, L. R., Gökalp, A. L., Van Kimmenade, R. R. J., Mokhles, M. M., Pelliccia, A., Takkenberg, J. J. M., & Roos-Hesselink, J. W. (2019) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2019.1585807 · Cited by 63
Profiling risk: the emergence of coronary heart disease epidemiology in the United States (1947–70)
Oppenheimer, G. M. (2006) · International Journal of Epidemiology · doi:10.1093/ije/dyl014 · Cited by 62
Occupational Physical Activity and the Degree of Coronary Atherosclerosis in "Normal" Men: A Postmortem Study
SPAIN, D. M., & BRADESS, V. A. (1960) · Circulation · doi:10.1161/01.cir.22.2.239 · Cited by 56
Health effects resulting from exercise versus those from body fat loss
WILLIAMS, P. T. (2001) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200106001-00030 · Cited by 47
Associations between physical activity and cardiometabolic risk factors assessed in a southern California health care system, 2010-2012
Young, D. R., Coleman, K. J., Ngor, E., Reynolds, K., Sidell, M., & Sallis, R. E. (2014) · Preventing Chronic Disease · doi:10.5888/pcd11.140196 · Cited by 46
Rationale and study design for a randomised controlled trial to reduce sedentary time in adults at risk of type 2 diabetes mellitus: project stand (Sedentary Time ANd diabetes)
Wilmot, E. G., Davies, M. J., Edwardson, C. L., Gorely, T., Khunti, K., Nimmo, M., Yates, T., & Biddle, S. J. (2011) · BMC Public Health · doi:10.1186/1471-2458-11-908 · Cited by 42
Effectiveness of lifestyle physical activity interventions to reduce cardiovascular disease
Dunn, A. L. (2009) · American Journal of Lifestyle Medicine · doi:10.1177/1559827609336067 · Cited by 37
Validation study of Polar V800 accelerometer
Hernández-Vicente, A., Santos-Lozano, A., De Cocker, K., & Garatachea, N. (2016) · Annals of Translational Medicine · doi:10.21037/atm.2016.07.16 · Cited by 23
Metabolic deterioration of the sedentary control group in clinical trials
Patel, M. J., Slentz, C. A., & Kraus, W. E. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00421.2011 · Cited by 12
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Skogstad, M., Lunde, L.-K., Ulvestad, B., Aass, H., Clemm, T., Mamen, A., & Skare, Ø. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15020264 · Cited by 9

Authors: Morris, J. N., Heady, J. A., Raffle, P. A. B., Roberts, C. G., & Parks, J. W.
Venue: The Lancet
Publisher: Elsevier BV
Published: 1953-11
Volume: 262
Issue: 6795
Pages: 1053-1057
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/s0140-6736(53)90665-5
OpenAlex: W2157064067
Cited by: 1,698
References: 0
FWCI: 34.72
Type: journal article
Language: en
Open access: closed

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