Cited by 307Neurotransmitter Receptor Influence on BehaviorRegulation of Appetite and ObesityNeural and Behavioral Psychology Studies

The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.

Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat

Open access

Davis, Jon F., Tracy, Andrea L., Schurdak, Jennifer D., Tschöp, Matthias H., Lipton, Jack W., Clegg, Deborah J., Benoit, Stephen C.·2008·Behavioral Neuroscience

DOI 10.1037/a0013111PMC PMC2597276

Open this paper in CoChat — free account

Abstract

Recent studies indicate that decreased central dopamine is associated with diet-induced obesity in humans and in animal models. In the current study, the authors assessed the hypothesis that diet-induced obesity reduces mesolimbic dopamine function. Specifically, the authors compared dopamine turnover in this region between rats fed a high-fat diet and those consuming a standard low-fat diet. The authors also assessed behavioral consequences of diet-induced obesity by testing the response of these animals in a conditioned place paradigm using amphetamine as a reinforcer and in an operant conditioning paradigm using sucrose reinforcement. Results demonstrate that animals consuming a high-fat diet, independent of the development of obesity, exhibit decreased dopamine turnover in the mesolimbic system, reduced preference for an amphetamine cue, and attenuated operant responding for sucrose. The authors also observed that diet-induced obesity with a high-fat diet attenuated mesolimbic dopamine turnover in the nucleus accumbens. These data are consistent with recent hypotheses that the hormonal signals derived from adipose tissue regulate the activity of central nervous system structures involved in reward and motivation, which may have implications for the treatment of obesity and/or addiction.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1037/a0013111

Cites

53 of 53 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The evidence report
(1998) · PsycEXTRA Dataset · doi:10.1037/e565682010-001 · Cited by 9,453
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
Mokdad, A. H., Ford, E. S., Bowman, B. A., Dietz, W. H., Vinicor, F., Bales, V. S., & Marks, J. S. (2003) · JAMA · doi:10.1001/jama.289.1.76 · Cited by 5,866
The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
Stanietsky, N., Simic, H., Arapovic, J., Toporik, A., Levy, O., Novik, A., Levine, Z., Beiman, M., Dassa, L., Achdout, H., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903474106 · Cited by 3,524
A Potential Decline in Life Expectancy in the United States in the 21st Century
Olshansky, S. J., Passaro, D. J., Hershow, R. C., Layden, J., Carnes, B. A., Brody, J., Hayflick, L., Butler, R. N., Allison, D. B., & Ludwig, D. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmsr043743 · Cited by 2,612
Physiology and Behavior
Falk, J. L. (1973) · Contemporary Psychology · doi:10.1037/0011818 · Cited by 2,288
A Potential Decline in Life Expectancy in the United States in the 21st Century
Olshansky, S. J., Passaro, D. J., Hershow, R. C., Layden, J. E., Carnes, B. A., Brody, J. A., Hayflick, L., Butler, R. N., Allison, D. B., & Ludwig, D. S. (2005) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000167407.83915.e7 · Cited by 1,947
Parsing reward
Berridge, K. C., & Robinson, T. E. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00233-9 · Cited by 1,869
Brain dopamine and obesity
Wang, G.-J., Volkow, N. D., Logan, J., Pappas, N. R., Wong, C. T., Zhu, W., Netusll, N., & Fowler, J. S. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03643-6 · Cited by 1,864
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
Gaal, L. F. V., Rissanen, A., Scheen, A. J., Ziegler, O., & Rössner, S. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66374-x · Cited by 1,511
Multiple dopamine functions at different time courses
Schultz, W. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135722 · Cited by 1,415

Show all 50 references

Sorted by citations

Obesity and addiction: Neurobiological overlaps
Volkow, N. D., Wang, G. ‐., Tomasi, D., & Baler, R. D. (2013) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01031.x · Cited by 800
Reward mechanisms in obesity: new insights and future directions
Kenny, P. J. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.016 · Cited by 748
Obese adults have visual attention bias for food cue images: Evidence for altered reward system function
Castellanos, E. H., Charboneau, E., Dietrich, M. S., Park, S., Bradley, B. P., Mogg, K., & Cowan, R. L. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.138 · Cited by 564
Dopamine Signaling in reward-related behaviors
Baik, J. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00152 · Cited by 568
Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity
Val‐Laillet, D., Aarts, E., Weber, B., Ferrari, M., Quaresima, V., Stoeckel, L. E., Alonso‐Alonso, M., Audette, M. A., Malbert, C., & Stice, E. M. (2015) · NeuroImage Clinical · doi:10.1016/j.nicl.2015.03.016 · Cited by 466
The menace of obesity to depression and anxiety prevalence
Fulton, S., Décarie-Spain, L., Fioramonti, X., Guiard, B., & Nakajima, S. (2022) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2021.10.005 · Cited by 441
Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry
Sharma, S., & Fulton, S. (2013) · International Journal of Obesity · doi:10.1038/ijo.2012.48 · Cited by 424
The Addictive Dimensionality of Obesity
Volkow, N. D., Wang, G.-J., Tomasi, D., & Baler, R. D. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.12.020 · Cited by 380
Natural rewards, neuroplasticity, and non-drug addictions
Olsen, C. M. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.03.010 · Cited by 339
Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition
Kang, S. S., Jeraldo, P., Kurti, A., Miller, M. E. B., Cook, M. D., Whitlock, K. G., Goldenfeld, N. D., Woods, J. A., White, B. A., Chia, N., et al. (2014) · Molecular Neurodegeneration · doi:10.1186/1750-1326-9-36 · Cited by 331
A Gut Lipid Messenger Links Excess Dietary Fat to Dopamine Deficiency
Téllez, L. A., Medina, S., Han, W., Ferreira, J. G. P., Licona-Limón, P., Ren, X., Lam, T. T., Schwartz, G. J., & de Araújo, I. E. (2013) · Science · doi:10.1126/science.1239275 · Cited by 300
Food reward, hyperphagia, and obesity
Berthoud, H.-R., Lenard, N. R., & Shin, A. C. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00028.2011 · Cited by 275
The contribution of brain reward circuits to the obesity epidemic
Stice, E., Figlewicz, D. P., Gosnell, B. A., Levine, A. S., & Pratt, W. E. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.12.001 · Cited by 274
Hormonal and neural mechanisms of food reward, eating behaviour and obesity
Murray, S. M., Tulloch, A. J., Gold, M. S., & Avena, N. M. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.91 · Cited by 275
Prevention and treatment of drug addiction by environmental enrichment
Solinas, M., Thiriet, N., Chauvet, C., & Jaber, M. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.08.002 · Cited by 270
The role of orexin-A in food motivation, reward-based feeding behavior and food-induced neuronal activation in rats
Choi, D. L., Davis, J. F., Fitzgerald, M. E., & Benoit, S. C. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.02.002 · Cited by 239
Self-citation
Adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high-fat diet withdrawal
Sharma, S., Fernandes, M. F., & Fulton, S. (2013) · International Journal of Obesity · doi:10.1038/ijo.2012.197 · Cited by 231
Stress exposure, food intake and emotional state.
Ulrich‐Lai, Y. M., Fulton, S., Wilson, M., Petrovich, G. D., & Rinaman, L. (2015) · PubMed · doi:10.3109/10253890.2015.1062981 · Cited by 225
Insulin, leptin, and food reward: update 2008
Figlewicz, D. P., & Benoit, S. C. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90725.2008 · Cited by 205
Self-citation
Addiction science: Uncovering neurobiological complexity
Volkow, N. D., & Baler, R. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.05.007 · Cited by 205
Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced obesity phenotype in rats
Alsiö, J., Olszewski, P. K., Norbäck, A. H., Gunnarsson, Z. E., Levine, A. S., Pickering, C., & Schiöth, H. B. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.09.046 · Cited by 189
Obesity: Current and potential pharmacotherapeutics and targets
Narayanaswami, V., & Dwoskin, L. P. (2016) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2016.10.015 · Cited by 188
The impact of dietary macronutrient intake on cognitive function and the brain
Muth, A.-K., & Park, S. Q. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.04.043 · Cited by 213
Individual Differences in Cue-Induced Motivation and Striatal Systems in Rats Susceptible to Diet-Induced Obesity
Robinson, M. J. F., Burghardt, P. R., Patterson, C. M., Nobile, C. W., Akil, H., Watson, S. J., Berridge, K. C., & Ferrario, C. R. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.71 · Cited by 189
Neural vulnerability factors that increase risk for future weight gain
Stice, E., & Yokum, S. (2016) · Psychological Bulletin · doi:10.1037/bul0000044 · Cited by 179
Hedonic and incentive signals for body weight control
Egecioglu, E., Skibicka, K. P., Hansson, C., Álvarez-Crespo, M., Friberg, P. A., Jerlhag, E., Engel, J. A., & Dickson, S. L. (2011) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-011-9166-4 · Cited by 192
Leptin Regulates Energy Balance and Motivation Through Action at Distinct Neural Circuits
Davis, J. F., Choi, D. L., Schurdak, J. D., Fitzgerald, M. F., Clegg, D. J., Lipton, J. W., Figlewicz, D. P., & Benoit, S. C. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.08.028 · Cited by 169
Self-citation
Chronic High-Fat Diet Drives Postnatal Epigenetic Regulation of μ-Opioid Receptor in the Brain
Vucetic, Z., Kimmel, J. N., & Reyes, T. M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.4 · Cited by 166
Dopamine signaling in food addiction: role of dopamine D2 receptors
Baik, J. (2013) · BMB Reports · doi:10.5483/bmbrep.2013.46.11.207 · Cited by 173
Neurodegeneration in an animal model of Parkinson’s disease is exacerbated by a high-fat diet
Morris, J. K., Bomhoff, G. L., Stanford, J. A., & Geiger, P. C. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00449.2010 · Cited by 163
Neural vulnerability factors for obesity
Stice, E. M., & Burger, K. S. (2018) · Clinical Psychology Review · doi:10.1016/j.cpr.2018.12.002 · Cited by 161
Epigenetic dysregulation of the dopamine system in diet‐induced obesity
Vucetic, Z., Carlin, J. L., Totoki, K., & Reyes, T. M. (2012) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2012.07649.x · Cited by 162
Insulin resistance impairs nigrostriatal dopamine function
Morris, J. K., Bomhoff, G. L., Gorres, B. K., Davis, V. A., Kim, J., Lee, P., Brooks, W. M., Gerhardt, G. A., Geiger, P. C., & Stanford, J. A. (2011) · Experimental Neurology · doi:10.1016/j.expneurol.2011.06.005 · Cited by 155
Microbiota‐gut‐brain axis as a regulator of reward processes
García‐Cabrerizo, R., Carbia, C., O’Riordan, K. J., Schellekens, H., & Cryan, J. F. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15284 · Cited by 150
Central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity
Vucetic, Z., & Reyes, T. M. (2010) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.77 · Cited by 145
Hungry brains: A meta-analytical review of brain activation imaging studies on food perception and appetite in obese individuals
Devoto, F., Zapparoli, L., Bonandrini, R., Berlingeri, M., Ferrulli, A., Luzi, L., Banfi, G., & Paulesu, E. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.07.017 · Cited by 140
Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources
Beeler, J. A., Frazier, C. R. M., & Zhuang, X. (2012) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2012.00049 · Cited by 136
Roux-en-Y gastric bypass surgery changes food reward in rats
Shin, A. C., Zheng, H., Pistell, P. J., & Berthoud, H.-R. (2011) · International Journal of Obesity · doi:10.1038/ijo.2010.174 · Cited by 133
The snacking rat as model of human obesity: effects of a free-choice high-fat high-sugar diet on meal patterns
la Fleur, S. E., Luijendijk, M. C. M., van der Zwaal, E. M., Brans, M. A. D., & Adan, R. A. H. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.159 · Cited by 130
Insulin, leptin and reward
Davis, J. F., Choi, D. L., & Benoit, S. C. (2010) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2009.08.004 · Cited by 129
Self-citation
Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring
Naef, L., Moquin, L., Bo, G. D., Bruno Giros, A., Gratton, A. P., & Walker, C. D. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.12.037 · Cited by 126
Reduced accumbens dopamine in Sprague–Dawley rats prone to overeating a fat-rich diet
Rada, P. V., Bocarsly, M. E., Barson, J. R., Hoebel, B. G., & LEIBOWITZ, S. F. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.07.005 · Cited by 124
Basal Ganglia Dysfunction Contributes to Physical Inactivity in Obesity
Friend, D. M., Devarakonda, K., O’Neal, T. J., Skirzewski, M., Papazoglou, I., Kaplan, A. R., Liow, J., Guo, J., Rane, S. G., Rubinstein, M., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.12.001 · Cited by 121
Dampened mesolimbic dopamine function and signaling by saturated but not monounsaturated dietary lipids
Hryhorczuk, C., Florea, M., Rodaros, D., Poirier, I., Daneault, C., Des Rosiers, C., Arvanitogiannis, A., Alquier, T., & Fulton, S. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.207 · Cited by 119
“Liking” and “wanting” of sweet and oily food stimuli as affected by high-fat diet-induced obesity, weight loss, leptin, and genetic predisposition
Shin, A. C., Townsend, R. L., Patterson, L. M., & Berthoud, H. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00314.2011 · Cited by 110
Energy regulatory signals and food reward
Figlewicz, D. P., & Sipols, A. J. (2010) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2010.03.002 · Cited by 116
Prolonged High Fat Diet Reduces Dopamine Reuptake without Altering DAT Gene Expression
Cone, J. J., Chartoff, E. H., Potter, D. N., Ebner, S. R., & Roitman, M. F. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058251 · Cited by 108
Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding
Speed, N. K., Saunders, C., Davis, A. R., Owens, W. A., Matthies, H. J. G., Saadat, S., Kennedy, J. P., Vaughan, R. A., Neve, R. L., Lindsley, C. W., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025169 · Cited by 107
A high-fat diet exacerbates depressive-like behavior in the Flinders Sensitive Line (FSL) rat, a genetic model of depression
Abildgaard, A. M., Solskov, L., Volke, V., Harvey, B. H., Lund, S. A., & Wegener, G. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.09.004 · Cited by 104
Diet-induced obesity: dopamine transporter function, impulsivity and motivation
Narayanaswami, V., Thompson, A. C., Cassis, L. A., Bardo, M. T., & Dwoskin, L. P. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.178 · Cited by 106
Reversal of dopamine system dysfunction in response to high‐fat diet
Carlin, J., Hill‐Smith, T. E., Lucki, I., & Reyes, T. M. (2013) · Obesity · doi:10.1002/oby.20374 · Cited by 101
Dopaminergic dysregulation in mice selectively bred for excessive exercise or obesity
Mathes, W. F., Nehrenberg, D. L., Gordon, R. R., Hua, K., Garland, T., & Pomp, D. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.02.016 · Cited by 98
The neurobiological and behavioral overlaps of nicotine and food addiction
Criscitelli, K., & Avena, N. M. (2016) · Preventive Medicine · doi:10.1016/j.ypmed.2016.08.009 · Cited by 99
Low Dopamine D2 Receptor Increases Vulnerability to Obesity Via Reduced Physical Activity, Not Increased Appetitive Motivation
Beeler, J. A., Faust, R. P., Turkson, S., Ye, H., & Zhuang, X. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.07.009 · Cited by 100
High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task
McNeilly, A. D., Williamson, R., Sutherland, C. D., Balfour, D. J. K., & Stewart, C. A. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.10.017 · Cited by 101
Hunger and Satiety Gauge Reward Sensitivity
Cassidy, R. M., & Tong, Q. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00104 · Cited by 93
Neurobiology of overeating and obesity: The role of melanocortins and beyond
Pandit, R., de Jong, J. W., Vanderschuren, L. J. M. J., & Adan, R. A. H. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2011.01.034 · Cited by 95
Long‐term, calorie‐restricted intake of a high‐fat diet in rats reduces impulse control and ventral striatal D2 receptor signalling – two markers of addiction vulnerability
Adams, W. K., Sussman, J. L., Kaur, S., D'souza, A. M., Kieffer, T. J., & Winstanley, C. A. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.13117 · Cited by 91
Neuroprotective effects of metformin against Aβ-mediated inhibition of long-term potentiation in rats fed a high-fat diet
Asadbegi, M., Yaghmaei, P., Salehi, I., Ebrahim‐Habibi, A., & Komaki‬, A. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.02.005 · Cited by 87
Insulin signaling and addiction
Daws, L. C., Avison, M. J., Robertson, S. D., Niswender, K. D., Galli, A., & Saunders, C. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.02.028 · Cited by 88
Neurochemical and electrophysiological deficits in the ventral hippocampus and selective behavioral alterations caused by high-fat diet in female C57BL/6 mice
Krishna, S., Keralapurath, M. M., Lin, Z., Wagner, J. J., Serre, C. B. D. L., Harn, D. A., & Filipov, N. M. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.03.068 · Cited by 90
Food Restriction Increases Glutamate Receptor-Mediated Burst Firing of Dopamine Neurons
Branch, S. Y., Goertz, R. B., Sharpe, A. L., Pierce, J., Roy, S., Ko, D., Paladini, C. A., & Beckstead, M. J. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5099-12.2013 · Cited by 81
Dopamine-Based Reward Circuitry Responsivity, Genetics, and Overeating
Stice, E. M., Yokum, S., Zald, D. H., & Dagher, A. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_89 · Cited by 81
Feed-forward mechanisms: Addiction-like behavioral and molecular adaptations in overeating
Alsiö, J., Olszewski, P. K., Levine, A. S., & Schiöth, H. B. (2012) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2012.01.002 · Cited by 81
Effects of diet and insulin on dopamine transporter activity and expression in rat caudate‐putamen, nucleus accumbens, and midbrain
Jones, K. T., Woods, C., Zhen, J., Antonio, T., Carr, K. D., & Reith, M. E. A. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13930 · Cited by 80
Central & peripheral glucagon-like peptide-1 receptor signaling differentially regulate addictive behaviors
Sirohi, S., Schurdak, J. D., Seeley, R. J., Benoit, S. C., & Davis, J. F. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.04.013 · Cited by 77
Self-citation
Weight suppression in bulimia nervosa: Associations with biology and behavior.
Bodell, L. P., & Keel, P. K. (2015) · Journal of Abnormal Psychology · doi:10.1037/abn0000077 · Cited by 78
The impact of maternal cafeteria diet on anxiety-related behaviour and exploration in the offspring
Wright, T. M., Langley‐Evans, S. C., & Voigt, J. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.01.008 · Cited by 72
Contribution of the mesolimbic dopamine system in mediating the effects of leptin and ghrelin on feeding
van Zessen, R., Plasse, G., & Adan, R. A. H. (2012) · Proceedings of The Nutrition Society · doi:10.1017/s0029665112000614 · Cited by 72
Mesolimbic dopamine and its neuromodulators in obesity and binge eating
Naef, L., Pitman, K. A., & Borgland, S. L. (2015) · CNS Spectrums · doi:10.1017/s1092852915000693 · Cited by 70
High-fat diet exacerbates cognitive rigidity and social deficiency in the BTBR mouse model of autism
Zilkha, N., Kuperman, Y., & Kimchi, T. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.01.070 · Cited by 72
Exposure to maternal consumption of cafeteria diet during the lactation period programmes feeding behaviour in the rat
Wright, T. M., Fone, K. C. F., Langley‐Evans, S. C., & Voigt, J. W. (2011) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2011.09.007 · Cited by 69
Neural Responses to Macronutrients: Hedonic and Homeostatic Mechanisms
Tulloch, A. J., Murray, S. M., Vaicekonyte, R., & Avena, N. M. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.12.058 · Cited by 67
Caffeine prevents weight gain and cognitive impairment caused by a high-fat diet while elevating hippocampal BDNF
Moy, G. A., & McNay, E. C. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.11.008 · Cited by 68
Western diet increases wheel running in mice selectively bred for high voluntary wheel running
Meek, T. H., Eisenmann, J. C., & Garland, T. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.25 · Cited by 66
A history of bingeing on fat enhances cocaine seeking and taking.
Puhl, M. D., Cason, A. M., Wojnicki, F. H. E., Corwin, R. L., & Grigson, P. S. (2011) · Behavioral Neuroscience · doi:10.1037/a0025759 · Cited by 66
Pathophysiology linking depression and type 2 diabetes: Psychotherapy, physical exercise, and fecal microbiome transplantation as damage control
Subba, R., Sandhir, R., Singh, S. P., Mallick, B. N., & Mondal, A. C. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15136 · Cited by 69
Food reward functions as affected by obesity and bariatric surgery
Shin, A. C., & Berthoud, H. R. (2011) · International Journal of Obesity · doi:10.1038/ijo.2011.147 · Cited by 68
Dietary triglycerides act on mesolimbic structures to regulate the rewarding and motivational aspects of feeding
Cansell, C., Castel, J., Denis, R., Rouch, C., Delbes, A.-S., Martinez, S., Mestivier, D., Finan, B., Maldonado‐Avilés, J. G., Rijnsburger, M., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.31 · Cited by 69
Self-citation
Circulating Triglycerides Gate Dopamine-Associated Behaviors through DRD2-Expressing Neurons
Berland, C., Montalban, E., Perrin, E., Miceli, M. D., Nakamura, Y., Martinat, M., Sullivan, M., Davis, X. S., Shenasa, M. A., Martin, C., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2020.02.010 · Cited by 70
Self-citation
Food reward in the obese and after weight loss induced by calorie restriction and bariatric surgery
Berthoud, H., Zheng, H., & Shin, A. C. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06573.x · Cited by 67
Removal of high-fat diet after chronic exposure drives binge behavior and dopaminergic dysregulation in female mice
Carlin, J. L., McKee, S. E., Hill‐Smith, T. E., Grissom, N. M., George, R., Lucki, I., & Reyes, T. M. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.04.002 · Cited by 63
Elevated Dopamine D2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [11C](+)PHNO
Gaiser, E. C., Gallezot, J.-D., Worhunsky, P. D., Jastreboff, A. M., Pittman, B., Kantrovitz, L., Angarita, G. A., Cosgrove, K. P., Potenza, M. N., Malison, R. T., et al. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.115 · Cited by 59
Diet-induced obesity causes ghrelin resistance in reward processing tasks
Lockie, S. H., Dinan, T., Lawrence, A. J., Spencer, S. J., & Andrews, Z. B. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.08.004 · Cited by 58
Opposing relationships of BMI with BOLD and dopamine D2/3 receptor binding potential in the dorsal striatum
Cosgrove, K., Veldhuizen, M. G., Sandiego, C. M., Morris, E. D., & Small, D. M. (2015) · Synapse · doi:10.1002/syn.21809 · Cited by 59
Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task
Finger, B. C., Dinan, T. G., & Cryan, J. F. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2468-0 · Cited by 59
Characterization of attenuated food motivation in high-fat diet-induced obesity: Critical roles for time on diet and reinforcer familiarity
Tracy, A. L., Wee, C. J. M., Hazeltine, G., & Carter, R. A. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.01.008 · Cited by 59
Self-citation
Anterior Paraventricular Thalamus to Nucleus Accumbens Projection Is Involved in Feeding Behavior in a Novel Environment
Cheng, J., Wang, J., Ma, X., Ullah, R., Shen, Y., & Zhou, Y. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00202 · Cited by 64
A pilot randomized trial of a cognitive reappraisal obesity prevention program
Stice, E. M., Yokum, S., Burger, K. S., Rohde, P., Shaw, H. E., & Gau, J. M. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.10.022 · Cited by 60
Persistent effects of obesity: A neuroplasticity hypothesis
Matikainen‐Ankney, B. A., & Kravitz, A. V. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13665 · Cited by 56
Gut microbes and food reward: From the gut to the brain
d’Oplinter, A. D. W., Huwart, S. J. P., Cani, P. D., & Everard, A. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.947240 · Cited by 57
Impact of Early Consumption of High-Fat Diet on the Mesolimbic Dopaminergic System
Naneix, F., Tantot, F., Glangetas, C., Kaufling, J., Janthakhin, Y., Boitard, C., Smedt, V. D., Pape, J., Vancassel, S., Trifilieff, P., et al. (2017) · eNeuro · doi:10.1523/eneuro.0120-17.2017 · Cited by 64
The early origins of food preferences: targeting the critical windows of development
Gugusheff, J., Ong, Z. Y., & Mühlhäusler, B. S. (2014) · The FASEB Journal · doi:10.1096/fj.14-255976 · Cited by 60
Chronic high-fat diet affects food-motivated behavior and hedonic systems in the nucleus accumbens of male rats
Arcego, D. M., Krolow, R., Lampert, C., Toniazzo, A. P., Garcia, E. D. S., Lazzaretti, C., Costa, G., Scorza, C., & Dalmaz, C. (2020) · Appetite · doi:10.1016/j.appet.2020.104739 · Cited by 54
Brain control of energy homeostasis: implications for anti-obesity pharmacotherapy
Johansen, V. B. I., Petersen, J., Lund, J., Mathiesen, C. V., Fenselau, H., & Clemmensen, C. (2025) · Cell · doi:10.1016/j.cell.2025.06.010 · Cited by 53
Insulin receptor activation in the nucleus accumbens reflects nutritive value of a recently ingested meal
Woods, C. A., Guttman, Z. R., Huang, D., Kolaric, R., Rabinowitsch, A. I., Jones, K. T., de Vaca, S. C., Sclafani, A. J., & Carr, K. D. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.03.013 · Cited by 52
Shift of Circadian Feeding Pattern by High-Fat Diets Is Coincident with Reward Deficits in Obese Mice
Morales, L., Olmo, N. D., Valladolid‐Acebes, I., Fole, A., Cano, V., Merino, B., Stucchi, P., Ruggieri, D., López, L., Alguacil, L. F., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036139 · Cited by 51
Roux-en-Y Gastric Bypass Increases Intravenous Ethanol Self-Administration in Dietary Obese Rats
Polston, J. E., Pritchett, C. E., Tomasko, J. M., Rogers, A. M., Leggio, L., Thanos, P. K., Volkow, N. D., & Hajnal, A. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083741 · Cited by 50
Neurological and stress related effects of shifting obese rats from a palatable diet to chow and lean rats from chow to a palatable diet
South, T., Westbrook, R. F., & Morris, M. J. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.11.019 · Cited by 50
An intermittent hypercaloric diet alters gut microbiota, prefrontal cortical gene expression and social behaviours in rats
Reichelt, A. C., Loughman, A., Bernard, A., Raipuria, M., Abbott, K. N., Dachtler, J., Van, T. T. H., & Moore, R. J. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2018.1537169 · Cited by 49

Authors: Davis, J. F., Tracy, A. L., Schurdak, J. D., Tschöp, M. H., Lipton, J. W., Clegg, D. J., & Benoit, S. C.
Affiliations: University of Cincinnati (US)
ORCID: Davis, Jon F.
Tracy, Andrea L.
Schurdak, Jennifer D.
Tschöp, Matthias H.
Lipton, Jack W.
Clegg, Deborah J.
Venue: Behavioral Neuroscience
Publisher: American Psychological Association (APA)
Published: 2008-12
Volume: 122
Issue: 6
Pages: 1257-1263
ISSN: 0735-7044 (ISSN-L)
1939-0084
DOI: 10.1037/a0013111
PMC: PMC2597276
OpenAlex: W2069303582
Cited by: 307
References: 50
Citations by year: 2026: 1 · 2025: 7 · 2024: 10 · 2023: 12 · 2022: 11 · 2021: 24 · 2020: 19 · 2019: 10 · 2018: 20 · 2017: 13 · 2016: 26 · 2015: 37 · 2014: 21 · 2013: 24 · 2012: 21
FWCI: 7.35
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Behavioral Neuroscience (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Diabetes and Digestive and Kidney Diseases (R01DK066223)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords: high-fat diet, diet-induced obesity, amphetamine, sucrose reinforcement, conditioned place preference, nucleus accumbens, reward and motivation, adipose tissue hormones, obesity treatment, addiction
MeSH terms: Amphetamine, Central Nervous System Stimulants, Analysis of Variance, Animals, Behavior, Animal, Conditioning, Operant, Dietary Fats, Dopamine, Limbic System, Locomotion, Male, Reinforcement Schedule, Reward, Sucrose, Sweetening Agents, Rats, Long-Evans, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks