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Photovoltaic retinal prosthesis restores high-resolution responses to single-pixel stimulation in blind retinas
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Abstract
Abstract Retinal prostheses hold the promise of restoring vision in totally blind people. However, a decade of clinical trials highlighted quantitative limitations hampering the possibility of reaching this goal. A key challenge in retinal stimulation is to independently activate retinal neurons over a large portion of the subject’s visual field. Reaching such a goal would significantly improve the perception accuracy in retinal implants’ users, along with their spatial cognition, attention, ambient mapping and interaction with the environment. Here we show a wide-field, high-density and high-resolution photovoltaic epiretinal prosthesis for artificial vision (POLYRETINA). The prosthesis embeds 10,498 physically and functionally independent photovoltaic pixels, allowing for wide retinal coverage and high-resolution stimulation. Single-pixel illumination reproducibly induced network-mediated responses from retinal ganglion cells at safe irradiance levels. Furthermore, POLYRETINA allowed response discrimination with a high spatial resolution equivalent to the pixel pitch (120 µm) thanks to the network-mediated stimulation mechanism. This approach could allow mid-peripheral artificial vision in patients with retinitis pigmentosa.
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“POLYRETINA reported ex-vivo a spatial resolution of 120 µm (or 20/480) equivalent to the electrode separation [132].”
From Advances in visual prostheses: engineering and biological challenges (2022) · cites this paper as [132]
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“POLYRETINA is a high-density wide-field epiretinal prosthesis containing 10 498 photovoltaic pixels distributed over an active area of approximately 43 • [38,39,131,132].”
From Advances in visual prostheses: engineering and biological challenges (2022) · cites this paper as [132]
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Cites
Unsupervised spike detection and sorting with wavelets and superparamagnetic clustering
Quiroga, R. Q., Nadasdy, Z., & Ben-Shaul, Y. (2004) · Neural Computation · doi:10.1162/089976604774201631 · Cited by 2,119
The functional diversity of retinal ganglion cells in the mouse
Baden, T., Berens, P., Franke, K., Román Rosón, M., Bethge, M., & Euler, T. (2016) · Nature · doi:10.1038/nature16468 · Cited by 999
Hamel, C. (2006) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-1-40 · Cited by 962
Perceptual grouping and attention in visual search for features and for objects.
Treisman, A. (1982) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037/0096-1523.8.2.194 · Cited by 908
Subretinal electronic chips allow blind patients to read letters and combine them to words
Zrenner, E., Bartz-Schmidt, K. U., Benav, H., Besch, D., Bruckmann, A., Gabel, V.-P., Gekeler, F., Greppmaier, U., Harscher, A., Kibbel, S., et al. (2011) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2010.1747 · Cited by 819
Interim results from the international trial of Second Sight's visual prosthesis
Humayun, M. S., Dorn, J. D., da Cruz, L., Dagnelie, G., Sahel, J.-A., Stanga, P. E., Cideciyan, A. V., Duncan, J. L., Eliott, D., Filley, E., et al. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2011.09.028 · Cited by 700
Hot exciton dissociation in polymer solar cells
Grancini, G., Maiuri, M., Fazzi, D., Petrozza, A., Egelhaaf, H., Brida, D., Cerullo, G., & Lanzani, G. (2012) · Nature Materials · doi:10.1038/nmat3502 · Cited by 659
Gargini, C., Tozzini, E. T., Mazzoni, F., & Strettoi, E. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.21144 · Cited by 496
Dendritic field size and morphology of midget and parasol ganglion cells of the human retina.
Dacey, D. M., & Petersen, M. R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.20.9666 · Cited by 487
Maximum permissible exposures for ocular safety (ANSI 2000), with emphasis on ophthalmic devices
Delori, F. C., Webb, R. H., & Sliney, D. H. (2007) · Journal of the Optical Society of America A · doi:10.1364/josaa.24.001250 · Cited by 484
The mosaic of midget ganglion cells in the human retina
Dacey, D. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-12-05334.1993 · Cited by 480
Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Braun, A., Bruckmann, A., Gekeler, F., Greppmaier, U., Hipp, S., Hörtdörfer, G., Kernstock, C., et al. (2013) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2013.0077 · Cited by 473
Photovoltaic retinal prosthesis with high pixel density
Mathieson, K., Loudin, J., Goetz, G. A., Huie, P., Wang, L., Kamins, T. I., Galambos, L., Smith, R., Harris, J. S., Sher, A., et al. (2012) · Nature Photonics · doi:10.1038/nphoton.2012.104 · Cited by 460
Veraart, C., Raftopoulos, C., Mortimer, J. T., Delbeke, J., Pins, D., Michaux, G., Vanlierde, A., Parrini, S., & Wanet-Defalque, M.-C. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00977-9 · Cited by 418
A neural interface for a cortical vision prosthesis
Normann, R. A., Maynard, E. M., Rousche, P. J., & Warren, D. J. (1999) · Vision Research · doi:10.1016/s0042-6989(99)00040-1 · Cited by 411
Chang, B., Hawes, N. L., Pardue, M. T., German, A. M., Hurd, R. E., Davisson, M. T., Nusinowitz, S., Rengarajan, K., Boyd, A. P., Sidney, S. S., et al. (2007) · Vision Research · doi:10.1016/j.visres.2006.11.020 · Cited by 395
Subretinal visual implant alpha IMS - clinical trial interim report
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Chee, C. K., Cottriall, C. L., Gekeler, F., Groppe, M., Jackson, T. L., MacLaren, R. E., Koitschev, A., et al. (2015) · Vision Research · doi:10.1016/j.visres.2015.03.001 · Cited by 387
Mechanical characterization of PEDOT:PSS thin films
Lang, U., Naujoks, N., & Dual, J. (2008) · Synthetic Metals · doi:10.1016/j.synthmet.2008.11.005 · Cited by 366
Five-year safety and performance results from the argus II retinal prosthesis system clinical trial.
da Cruz, L., Dorn, J. D., Humayun, M. S., Dagnelie, G., Handa, J., Barale, P.-O., Sahel, J.-A., Stanga, P. E., Hafezi, F., Safran, A. B., et al. (2016) · Ophthalmology · doi:10.1016/j.ophtha.2016.06.049 · Cited by 359
The Argus® II Retinal Prosthesis System
Luo, Y. H.-L., & da Cruz, L. (2016) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.09.003 · Cited by 351
Photovoltaic restoration of sight with high visual acuity
Lorach, H., Goetz, G., Smith, R., Lei, X., Mandel, Y., Kamins, T. I., Mathieson, K., Huie, P., Harris, J. S., Sher, A., et al. (2015) · Nature Medicine · doi:10.1038/nm.3851 · Cited by 341
Design of a high-resolution optoelectronic retinal prosthesis
Palanker, D., Vankov, A., Huie, P., & Baccus, S. A. (2005) · Journal of Neural Engineering · doi:10.1088/1741-2560/2/1/012 · Cited by 330
A polymer optoelectronic interface restores light sensitivity in blind rat retinas
Ghezzi, D., Antognazza, M. R., Maccarone, R., Bellani, S., Lanzarini, E., Martino, N., Mete, M., Pertile, G., Bisti, S., Lanzani, G., et al. (2013) · Nature Photonics · doi:10.1038/nphoton.2013.34 · Cited by 327
Self-citationA hybrid bioorganic interface for neuronal photoactivation
Ghezzi, D., Antognazza, M. R., Maschio, M. D., Lanzarini, E., Benfenati, F., & Lanzani, G. (2011) · Nature Communications · doi:10.1038/ncomms1164 · Cited by 313
Self-citationA fully organic retinal prosthesis restores vision in a rat model of degenerative blindness
Maya‐Vetencourt, J. F., Ghezzi, D., Antognazza, M. R., Colombo, E., Mete, M., Feyen, P., Desii, A., Buschiazzo, A., Paolo, M. D., Marco, S. D., et al. (2017) · Nature Materials · doi:10.1038/nmat4874 · Cited by 294
Self-citationAhuja, A. K., Dorn, J. D., Caspi, A., McMahon, M. J., Dagnelie, G., daCruz, L., Stanga, P., Humayun, M. S., Greenberg, R. J., & Argus II Study Group (2011) · British Journal of Ophthalmology · doi:10.1136/bjo.2010.179622 · Cited by 289
Retinal stimulation strategies to restore vision: fundamentals and systems
Yue, L., Weiland, J. D., Roska, B., & Humayun, M. S. (2016) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2016.05.002 · Cited by 272
Ganglion cell distribution in the retina of the mouse.
Dräger, U. C., & Olsen, J. F. (1981) · PubMed · Cited by 262
Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind
Ho, A. C., Humayun, M. S., Dorn, J. D., da Cruz, L., Dagnelie, G., Handa, J. T., Barale, P. O., Sahel, J., Stanga, P. E., Hafezi, F., et al. (2015) · Ophthalmology · doi:10.1016/j.ophtha.2015.04.032 · Cited by 262
Savagatrup, S., Printz, A. D., O’Connor, T. F., Zaretski, A. V., Rodriquez, D., Sawyer, E. J., Rajan, K. M., Acosta, R. I., Root, S. E., & Lipomi, D. J. (2014) · Energy & Environmental Science · doi:10.1039/c4ee02657h · Cited by 258
“Braille” reading by a blind volunteer by visual cortex stimulation
DOBELLE, W. H., MLADEJOVSKY, M. G., EVANS, J. R., ROBERTS, T. S., & GIRVIN, J. P. (1976) · Nature · doi:10.1038/259111a0 · Cited by 253
Four alpha ganglion cell types in mouse retina: Function, structure, and molecular signatures
Krieger, B. M., Qiao, M., Rousso, D. L., Sanes, J. R., & Meister, M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180091 · Cited by 251
Hammer, M., Roggan, A., Schweitzer, D., & Müller, G. (1995) · Physics in Medicine and Biology · doi:10.1088/0031-9155/40/6/001 · Cited by 249
In Vivo Human Choroidal Thickness Measurements: Evidence for Diurnal Fluctuations
Brown, J. S., Flitcroft, D. I., Ying, G., Francis, E. L., Schmid, G., Quinn, G. E., & Stone, R. A. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-1779 · Cited by 241
Mazzoni, F., Novelli, E., & Strettoi, E. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4968-08.2008 · Cited by 234
Lewis, P. M., Ackland, H. M., Lowery, A. J., & Rosenfeld, J. V. (2015) · Brain Research · doi:10.1016/j.brainres.2014.11.020 · Cited by 228
Photovoltaic Restoration of Central Vision in Atrophic Age-Related Macular Degeneration
Palanker, D., Le Mer, Y., Mohand-Said, S., Muqit, M., & Sahel, J. A. (2020) · Ophthalmology · doi:10.1016/j.ophtha.2020.02.024 · Cited by 227
Mobility performance with a pixelized vision system.
Cha, K., Horch, K. W., & Normann, R. A. (1992) · Vision Research · doi:10.1016/0042-6989(92)90229-c · Cited by 226
Edwards, T. L., Cottriall, C. L., Xue, K., Simunovic, M. P., Ramsden, J. D., Zrenner, E., & MacLaren, R. E. (2018) · Ophthalmology · doi:10.1016/j.ophtha.2017.09.019 · Cited by 193
Retinal implants: a systematic review: Table 1
Chuang, A., Margo, C. E., & Greenberg, P. B. (2014) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2013-303708 · Cited by 192
Fighting Blindness with Microelectronics
Zrenner, E. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3007399 · Cited by 192
Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesis
Ferlauto, L., Airaghi Leccardi, M. J. I., Chenais, N. A. L., Gilliéron, S. C. A., Vagni, P., Bevilacqua, M., Wolfensberger, T. J., Sivula, K., & Ghezzi, D. (2018) · Nature Communications · doi:10.1038/s41467-018-03386-7 · Cited by 183
Self-citationDorn, J. D., Ahuja, A. K., Caspi, A., da Cruz, L., Dagnelie, G., Sahel, J.-A., Greenberg, R. J., McMahon, M. J., & Argus II Study Group, F. T. (2013) · JAMA Ophthalmology · doi:10.1001/2013.jamaophthalmol.221 · Cited by 177
Improving the spatial resolution of epiretinal implants by increasing stimulus pulse duration
Weitz, A. C., Nanduri, D., Behrend, M. R., Gonzalez-Calle, A., Greenberg, R. J., Humayun, M. S., Chow, R. H., & Weiland, J. D. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aac4877 · Cited by 154
Pennesi, M. E., Michaels, K. V., Magee, S. S., Maricle, A., Davin, S., Garg, A., Gale, M. J., Tu, D. C., Wen, Y., Erker, L. R., et al. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-9611 · Cited by 151
Boinagrov, D., Pangratz-Fuehrer, S., Goetz, G., & Palanker, D. (2014) · Journal of Neural Engineering · doi:10.1088/1741-2560/11/2/026008 · Cited by 146
Nanowire arrays restore vision in blind mice
Tang, J., Qin, N., Chong, Y., Diao, Y., Yiliguma, Wang, Z., Xue, T., Jiang, M., Zhang, J., & Zheng, G. (2018) · Nature Communications · doi:10.1038/s41467-018-03212-0 · Cited by 142
Real and virtual mobility performance in simulated prosthetic vision
Dagnelie, G., Keane, P. A., Narla, V., Yang, L., Weiland, J. D., & Humayun, M. S. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/1/s11 · Cited by 136
Face recognition in age-related maculopathy.
Bullimore, M. A., Bailey, I. L., & Wacker, R. T. (1991) · PubMed · Cited by 128
A Polymer Optoelectronic Interface Provides Visual Cues to a Blind Retina
Gautam, V., Rand, D., Hanein, Y., & Narayan, K. S. (2013) · Advanced Materials · doi:10.1002/adma.201304368 · Cited by 127
Responses of ganglion cells to repetitive electrical stimulation of the retina
Jensen, R. J., & Rizzo, J. F. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/1/s01 · Cited by 121
Visual attention and perceptual grouping
Ben-Av, M. B., Sagi, D., & Braun, J. (1992) · Perception & Psychophysics · doi:10.3758/bf03209145 · Cited by 118
Stasheff, S. F., Shankar, M., & Andrews, M. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00704.2010 · Cited by 117
Depression and the vision-related quality of life in patients with retinitis pigmentosa
Hahm, B.-J., Shin, Y.-W., Shim, E.-J., Jeon, H.-J., Seo, J.-M., Chung, H., & Yu, H. G. (2008) · British Journal of Ophthalmology · doi:10.1136/bjo.2007.127092 · Cited by 114
Resolution of the epiretinal prosthesis is not limited by electrode size
Behrend, M. R., Ahuja, A. K., Humayun, M. S., Chow, R. H., & Weiland, J. D. (2011) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2011.2140132 · Cited by 102
Beyeler, M., Rokem, A., Boynton, G. M., & Fine, I. (2017) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa795e · Cited by 102
Near‐Infrared Tandem Organic Photodiodes for Future Application in Artificial Retinal Implants
Simone, G., Rasi, D. D. C., de Vries, X., Heintges, G. H. L., Meskers, S. C. J., Janssen, R. A. J., & Gelinck, G. H. (2018) · Advanced Materials · doi:10.1002/adma.201804678 · Cited by 100
Thermal Elevation in the Human Eye and Head Due to the Operation of a Retinal Prosthesis
Gosalia, K. C., Weiland, J. D., Humayun, M. S., & Lazzi, G. (2004) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2004.827548 · Cited by 95
Jacoby, J., & Schwartz, G. W. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.2804-16.2016 · Cited by 95
Light-evoked hyperpolarization and silencing of neurons by conjugated polymers
Feyen, P., Colombo, E., Endeman, D., Nova, M., Laudato, L., Martino, N., Antognazza, M. R., Lanzani, G., Benfenati, F., & Ghezzi, D. (2016) · Scientific Reports · doi:10.1038/srep22718 · Cited by 94
Self-citationDagnelie, G., Christopher, P., Arditi, A. R., da Cruz, L., Duncan, J. L., Ho, A. C., de Koo, L. C. O., Sahel, J., Stanga, P. E., Thumann, G., et al. (2016) · Clinical and Experimental Ophthalmology · doi:10.1111/ceo.12812 · Cited by 93
Detection of coherent movement in peripherally viewed random-dot patterns
van de GRIND, W. A., van Doorn, A. J., & Koenderink, J. J. (1983) · Journal of the Optical Society of America · doi:10.1364/josa.73.001674 · Cited by 91
Antognazza, M. R., Paolo, M. D., Ghezzi, D., Mete, M., Marco, S. D., Maya‐Vetencourt, J. F., Maccarone, R., Desii, A., Fonzo, F. D., Bramini, M., et al. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201600318 · Cited by 89
Self-citationRetinal prostheses: progress toward the next generation implants
Ghezzi, D. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00290 · Cited by 83
Self-citationErickson-Davis, C., & Korzybska, H. (2021) · PLoS ONE · doi:10.1371/journal.pone.0229189 · Cited by 83
Neural Mechanisms Mediating Motion Sensitivity in Parasol Ganglion Cells of the Primate Retina
Manookin, M. B., Patterson, S. S., & Linehan, C. M. (2018) · Neuron · doi:10.1016/j.neuron.2018.02.006 · Cited by 82
Multiple components of ganglion cell desensitization in response to prosthetic stimulation
Freeman, D. K., & Fried, S. I. (2011) · Journal of Neural Engineering · doi:10.1088/1741-2560/8/1/016008 · Cited by 80
Cellular Origin of Spontaneous Ganglion Cell Spike Activity in Animal Models of Retinitis Pigmentosa
Margolis, D. J., & Detwiler, P. B. (2010) · Journal of Ophthalmology · doi:10.1155/2011/507037 · Cited by 78
Young's modulus, fracture strain, and tensile strength of sputtered titanium thin films
Tsuchiya, T., Hirata, M., & Chiba, N. (2005) · Thin Solid Films · doi:10.1016/j.tsf.2005.02.024 · Cited by 77
Spatially selective activation of the visual cortex via intraneural stimulation of the optic nerve
Gaillet, V., Cutrone, A., Artoni, F., Vagni, P., Mega Pratiwi, A., Romero, S. A., Lipucci Di Paola, D., Micera, S., & Ghezzi, D. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0446-8 · Cited by 73
Self-citationBasic Quantitative Assessment of Visual Performance in Patients with Very Low Vision
Bach, M., Wilke, M., Wilhelm, B., Zrenner, E., & Wilke, R. G. H. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.09-3512 · Cited by 70
Behavioural responses to a photovoltaic subretinal prosthesis implanted in non-human primates
Prévot, P.-H., Gehere, K., Arcizet, F., Akolkar, H., Khoei, M. A., Blaize, K., Oubari, O., Daye, P. M., Lanoë, M., Valet, M., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0484-2 · Cited by 69
Contribution of two movement detecting mechanisms to central and peripheral vision
Murray, I. J., MacCana, F., & Kulikowski, J. J. (1983) · Vision Research · doi:10.1016/0042-6989(83)90138-4 · Cited by 67
Stimulation strategies for improving the resolution of retinal prostheses
Tong, W., Meffin, H., Garrett, D. J., & Ibbotson, M. R. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00262 · Cited by 66
Mechanical Behavior and Anisotropy of Spin-Coated SU-8 Thin Films for MEMS
Robin, C. J., Vishnoi, A., & Jonnalagadda, K. N. (2013) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2013.2264341 · Cited by 64
Photovoltaic organic interface for neuronal stimulation in the near-infrared
Airaghi Leccardi, M. J. I., Chenais, N. A. L., Ferlauto, L., Kawecki, M., Zollinger, E. G., & Ghezzi, D. (2020) · Communications Materials · doi:10.1038/s43246-020-0023-4 · Cited by 63
Self-citationSimulating prosthetic vision: II. Measuring functional capacity
Chen, S. C., Suaning, G. J., Morley, J. W., & Lovell, N. H. (2009) · Vision Research · doi:10.1016/j.visres.2009.07.003 · Cited by 59
Safety evaluation of “retina implant alpha IMS”—a prospective clinical trial
Kitiratschky, V. B. D., Štingl, K., Wilhelm, B., Peters, T. M., Besch, D., Sachs, H. G., Gekeler, F., Bartz‐Schmidt, K. U., & Zrenner, E. (2014) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-014-2797-x · Cited by 55
Polyimide/SU-8 catheter-tip MEMS gauge pressure sensor
Hasenkamp, W., Forchelet, D., Pataky, K. A., Villard, J., van Lintel, H., Bertsch, A., Wang, Q., & Renaud, P. (2012) · Biomedical Microdevices · doi:10.1007/s10544-012-9661-8 · Cited by 55
Fornos, A. P., Sommerhalder, J., Pittard, A., Safran, A. B., & Pelizzone, M. (2008) · Vision Research · doi:10.1016/j.visres.2008.04.027 · Cited by 50
Michels, R. G., Wilkinson, C. P., Rice, T. A., & Weinberg, A. B. (1991) · Retina · doi:10.1097/00006982-199110000-00031 · Cited by 46
Temperature distribution simulation of the human eye exposed to laser radiation.
Mirnezami, S. A., Jafarabadi, M. R., & Abrishami, M. (2013) · PubMed · Cited by 44
Optical absorption and scattering of bovine cornea, lens and retina in the visible region
Sardar, D. K., Yust, B. G., Barrera, F. J., Mimun, L. C., & Tsin, A. T. C. (2009) · Lasers in Medical Science · doi:10.1007/s10103-009-0677-0 · Cited by 40
Koehler, C. L., Akimov, N. P., & Renterı́a, R. C. (2011) · Journal of Neurophysiology · doi:10.1152/jn.01046.2010 · Cited by 39
Safety Studies for a 44-Channel Suprachoroidal Retinal Prosthesis: A Chronic Passive Study
Abbott, C. J., Nayagam, D. A. X., Luu, C. D., Epp, S. B., Williams, R. A., Rosa, C. M. S.-L., Villalobos, J., McGowan, C. C., Shivdasani, M. N., Burns, O., et al. (2018) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.17-23086 · Cited by 38
Thorn, J. T., Migliorini, E., & Ghezzi, D. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abb5bc · Cited by 34
Self-citationMorphology of wide-field, monostratified ganglion cells of the human retina
Peterson, B. B., & Dacey, D. M. (1999) · Visual Neuroscience · doi:10.1017/s0952523899161066 · Cited by 32
Lee, J.-I., & Im, M. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aad416 · Cited by 31
Implantation of modular photovoltaic subretinal prosthesis
Lee, D. Y., Lorach, H., Huie, P., & Palanker, D. (2016) · Ophthalmic Surgery, Lasers and Imaging Retina · doi:10.3928/23258160-20160126-11 · Cited by 30
The very large electrode array for retinal stimulation (VLARS)—A concept study
Lohmann, T., Haiss, F., Schaffrath, K., Schnitzler, A. C., Waschkowski, F., Barz, C. S., van der Meer, A.-M., Werner, C., Johnen, S., Laube, T., et al. (2019) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab4113 · Cited by 30
Retinal safety of near-infrared lasers in cataract surgery
Wang, J. Y., Sramek, C., Paulus, Y. M., Lavinsky, D., Schuele, G., Andersen, D. E., Dewey, D. A., & Palanker, D. (2012) · Journal of Biomedical Optics · doi:10.1117/1.jbo.17.9.095001 · Cited by 28
Chenais, N. A. L., Leccardi, M. J. I. A., & Ghezzi, D. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abcd6f · Cited by 28
Self-citationDirect measurement of bipolar cell responses to electrical stimulation in wholemount mouse retina
Walston, S. T., Chow, R. H.-P., & Weiland, J. D. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aab4ed · Cited by 28
The Subretinal Implant ALPHA: Implantation and Functional Results
Zrenner, E., Bartz-Schmidt, K. U., Besch, D., Gekeler, F., Koitschev, A., Sachs, H. G., & Stingl, K. (2017) · Artificial Vision · doi:10.1007/978-3-319-41876-6_6 · Cited by 27
Chenais, N. A. L., Leccardi, M. J. I. A., & Ghezzi, D. (2019) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab3913 · Cited by 24
Self-citationDetermination of retinal surface area
Nagra, M., Gilmartin, B., Thai, N. J., & Logan, N. S. (2017) · Journal of Anatomy · doi:10.1111/joa.12641 · Cited by 20
Yee, C. W., Toychiev, A. H., Ivanova, E., & Sagdullaev, B. T. (2014) · The Journal of Comparative Neurology · doi:10.1002/cne.23660 · Cited by 17
BIO-HEAT TRANSFER SIMULATION OF SQUARE AND CIRCULAR ARRAY OF RETINAL LASER IRRADIATION
Narasimhan, A., & Jha, K. K. (2011) · Frontiers in Heat and Mass Transfer · doi:10.5098/hmt.v2.3.3005 · Cited by 16
Nanoindentation of Soft Polymers: Modeling, Experiments and Parameter Identification
Chen, Z., & Diebels, S. (2014) · Otto-von-Guericke-Universität Magdeburg · doi:10.24352/ub.ovgu-2017-060 · Cited by 15
Isselé, H., Mercier, D., Guillaume Parry, A., Estevez, R., Vignoud, L., & Olagnon, C. (2012) · e-Journal of Surface Science and Nanotechnology · doi:10.1380/ejssnt.2012.624 · Cited by 14
High‐Frequency Stimulation of Normal and Blind Mouse Retinas Using TiO2 Nanotubes
Ronzani, C., Cottineau, T., González‐Valls, I., Keller, V., Picaud, S. A., Keller, N., & Roux, M. J. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201804639 · Cited by 13
Prospects and Limitations of Spatial Resolution
Sommerhalder, J., & Fornos, A. P. (2016) · Springer eBooks · doi:10.1007/978-3-319-41876-6_4 · Cited by 11
Visual Circuits: Mouse Retina No Longer a Level Playing Field
Dhande, O. S., & Huberman, A. D. (2014) · Current Biology · doi:10.1016/j.cub.2013.12.045 · Cited by 10
Human Factors in Healthcare: A Field Guide to Continuous Improvement
Parush, A. (2017) · Synthesis lectures on assistive, rehabilitative, and health-preserving technologies · doi:10.2200/s00753ed1v01y201701arh011 · Cited by 6
Evidence that L-AP5 and D,L-AP4 can preferentially block cone signals in the rat retina
Green, D. G., & KAPOUSTA-BRUNEAU, N. V. (2007) · Visual Neuroscience · doi:10.1017/s0952523807230123 · Cited by 5
Review: Visual Perception: Physiology, Psychology and Ecology
Smith, A. T. (1997) · Perception · doi:10.1068/p261211 · Cited by 3
Parush, A., Parush, D., & Ilan, R. (2017) · Synthesis lectures on assistive, rehabilitative, and health-preserving technologies · doi:10.1007/978-3-031-01602-8 · Cited by 2
Research works printed but not linked: 1
- Weiland, J. D. & Humayun, M. S. Retinal prosthetic systems for the treatment of blindness. Bridge 42, 51–57 (2012).
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Seo, H., Chung, W. G., Kwon, Y. W., Kim, S., Hong, Y., Park, W., Kim, E., Lee, J., Lee, S., Kim, M., et al. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00290 · Cited by 157
Metaverse Wearables for Immersive Digital Healthcare: A Review
Kim, K., Yang, H., Lee, J.-H., & Lee, W. G. (2023) · Advanced Science · doi:10.1002/advs.202303234 · Cited by 110
Monolithic silicon for high spatiotemporal translational photostimulation
Li, P., Zhang, J., Hayashi, H., Yue, J., Li, W., Yang, C., Sun, C., Shi, J., Huberman-Shlaes, J., Hibino, N., et al. (2024) · Nature · doi:10.1038/s41586-024-07016-9 · Cited by 100
Materials for Implantable Surface Electrode Arrays: Current Status and Future Directions
Tringides, C. M., & Mooney, D. J. (2021) · Advanced Materials · doi:10.1002/adma.202107207 · Cited by 73
Retinal Prostheses: Engineering and Clinical Perspectives for Vision Restoration
Wu, K. Y., Mina, M., Sahyoun, J.-Y., Kalevar, A., & Tran, S. D. (2023) · Sensors · doi:10.3390/s23135782 · Cited by 75
Metadata
- Authors
- Chenais, N. A. L., Airaghi Leccardi, M. J. I., & Ghezzi, D.
- Affiliations
- École Polytechnique Fédérale de Lausanne (CH)
- Corresponding author
- Ghezzi, Diego
- Venue
- Communications Materials
- Published
- 2021-03-05
- Volume
- 2
- Issue
- 1
- ISSN
- 2662-4443 (ISSN-L)
- OpenAlex
- W3134642074
- Cited by
- 110
- References
- 107
- Citations by year
- 2026: 11 · 2025: 20 · 2024: 32 · 2023: 17 · 2022: 18 · 2021: 10
- FWCI
- 8.90
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Communications Materials (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Velux Stiftung (1102)
- Gebert Rüf Stiftung (GRS-035/17)
- Fondation Pierre Mercier pour la Science Fondation Pro Visu
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Health Sciences › Medicine › Ophthalmology › Retinal Development and Disorders
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Advanced Memory and Neural Computing
- Keywords
- retinal prosthesis, epiretinal implants, retinitis pigmentosa, retinal ganglion cells, spatial resolution, artificial vision
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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