Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies
Open accessPublished version of a preprint
Abstract
The ‘bionic eye’—so long a dream of the future—is finally becoming a reality with retinal prostheses available to patients in both the US and Europe. However, clinical experience with these implants has made it apparent that the visual information provided by these devices differs substantially from normal sight. Consequently, the ability of patients to learn to make use of this abnormal retinal input plays a critical role in whether or not some functional vision is successfully regained. The goal of the present review is to summarize the vast basic science literature on developmental and adult cortical plasticity with an emphasis on how this literature might relate to the field of prosthetic vision. We begin with describing the distortion and information loss likely to be experienced by visual prosthesis users. We then define cortical plasticity and perceptual learning, and describe what is known, and what is unknown, about visual plasticity across the hierarchy of brain regions involved in visual processing, and across different stages of life. We close by discussing what is known about brain plasticity in sight restoration patients and discuss biological mechanisms that might eventually be harnessed to improve visual learning in these patients.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
This number might underestimate the real needs of implanted patients due to the perceptual and behavioural learning required to adapt to artificial vision.
“However, this number might underestimate the real needs of implanted patients due to the perceptual and behavioural learning required to adapt to artificial vision [121,122].”
From Advances in visual prostheses: engineering and biological challenges (2022) · cites this paper as [121]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Image quality assessment: from error visibility to structural similarity
Wang, Z., Bovik, A. C., Sheikh, H. R., & Simoncelli, E. P. (2004) · IEEE Transactions on Image Processing · doi:10.1109/tip.2003.819861 · Cited by 57,892 · see citing works
(1966) · Medical Entomology and Zoology · Cited by 10,293 · see citing works
Signal detection theory and psychophysics
Ingleby, D. (1967) · Journal of Sound and Vibration · doi:10.1016/0022-460x(67)90197-6 · Cited by 8,616 · see citing works
Critical period plasticity in local cortical circuits
Hensch, T. K. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1787 · Cited by 2,323 · see citing works
Hochstein (2002) · doi:10.1016/s0896-6273(02)01091-7 · Cited by 1,397 · see citing works
Wiesel, T. N., & Hubel, D. H. (1963) · Journal of Neurophysiology · doi:10.1152/jn.1963.26.6.978 · Cited by 1,291 · see citing works
Evidence for striatal dopamine release during a video game
Koepp, M. J., Gunn, R. N., Lawrence, A. D., Cunningham, V. J., Dagher, A., Jones, T., Brooks, D. J., Bench, C. J., & Grasby, P. M. (1998) · Nature · doi:10.1038/30498 · Cited by 1,279 · see citing works
Recanzone, G., Schreiner, C., & Merzenich, M. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-01-00087.1993 · Cited by 1,266 · see citing works
The influence of improvement in one mental function upon the efficiency of other functions. (I).
Woodworth, R. S., & Thorndike, E. L. (1901) · Psychological Review · doi:10.1037/h0074898 · Cited by 1,223 · see citing works
Huang, Z. J., Kirkwood, A., Pizzorusso, T., Porciatti, V., Morales, B., Bear, M. F., Maffei, L., & Tonegawa, S. (1999) · Cell · doi:10.1016/s0092-8674(00)81509-3 · Cited by 1,198 · see citing works
Playing an Action Video Game Reduces Gender Differences in Spatial Cognition
Feng, J., Spence, I., & Pratt, J. (2007) · Psychological Science · doi:10.1111/j.1467-9280.2007.01990.x · Cited by 1,155 · see citing works
Cross-modal plasticity: where and how?
Bavelier, D., & Neville, H. J. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn848 · Cited by 1,040 · see citing works
The reverse hierarchy theory of visual perceptual learning
Ahissar, M., & Hochstein, S. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.08.011 · Cited by 1,005 · see citing works
The antidepressant fluoxetine restores plasticity in the adult visual cortex
Vetencourt, J. F. M., Sale, A., Viegi, A., Baroncelli, L., De Pasquale, R., F. O'Leary, O., Castrén, E., & Maffei, L. (2008) · Science · doi:10.1126/science.1150516 · Cited by 890 · see citing works
Receptive field dynamics in adult primary visual cortex
Gilbert, C. D., & Wiesel, T. N. (1992) · Nature · doi:10.1038/356150a0 · Cited by 871 · see citing works
Practising orientation identification improves orientation coding in V1 neurons
Schoups, A., Vogels, R., Qian, N., & Orban, G. (2001) · Nature · doi:10.1038/35087601 · Cited by 856 · see citing works
Task difficulty and the specificity of perceptual learning
Ahissar, M., & Hochstein, S. (1997) · Nature · doi:10.1038/387401a0 · Cited by 823 · see citing works
Subretinal electronic chips allow blind patients to read letters and combine them to words
Zrenner, E., Bartz-Schmidt, K. U., Benav, H., Besch, D., Bruckmann, A., Gabel, V.-P., Gekeler, F., Greppmaier, U., Harscher, A., Kibbel, S., et al. (2011) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2010.1747 · Cited by 819 · see citing works
Parallel processing strategies of the primate visual system
Nassi, J. J., & Callaway, E. M. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2619 · Cited by 802 · see citing works
Critical periods in speech perception: New directions
Werker, J. F., & Hensch, T. K. (2015) · Annual Review of Psychology · doi:10.1146/annurev-psych-010814-015104 · Cited by 774 · see citing works
EXTENT OF RECOVERY FROM THE EFFECTS OF VISUAL DEPRIVATION IN KITTENS
Wiesel, T. N., & Hubel, D. H. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.6.1060 · Cited by 704 · see citing works
Organization of visual pathways in normal and visually deprived cats.
Sherman, S. M., & Spear, P. D. (1982) · Physiological Reviews · doi:10.1152/physrev.1982.62.2.738 · Cited by 704 · see citing works
Interim results from the international trial of Second Sight's visual prosthesis
Humayun, M. S., Dorn, J. D., da Cruz, L., Dagnelie, G., Sahel, J.-A., Stanga, P. E., Cideciyan, A. V., Duncan, J. L., Eliott, D., Filley, E., et al. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2011.09.028 · Cited by 700 · see citing works
The Neural Basis of Perceptual Learning
Gilbert, C. D., Sigman, M., & Crist, R. E. (2001) · Neuron · doi:10.1016/s0896-6273(01)00424-x · Cited by 688 · see citing works
Balancing Plasticity/Stability Across Brain Development
Takesian, A. E., & Hensch, T. K. (2013) · Progress in Brain Research · doi:10.1016/b978-0-444-63327-9.00001-1 · Cited by 667 · see citing works
Reorganization of Retinotopic Cortical Maps in Adult Mammals After Lesions of the Retina
Kaas, J. H., Krubitzer, L. A., Chino, Y. M., Langston, A., Polley, E. H., & Blair, N. P. (1990) · Science · doi:10.1126/science.2326637 · Cited by 647 · see citing works
Mechanisms underlying development of visual maps and receptive fields
Huberman, A. D., Feller, M. B., & Chapman, B. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.31.060407.125533 · Cited by 628 · see citing works
Axonal sprouting accompanies functional reorganization in adult cat striate cortex
Darian‐Smith, C., & Gilbert, C. D. (1994) · Nature · doi:10.1038/368737a0 · Cited by 601 · see citing works
Removing brakes on adult brain plasticity: From molecular to behavioral interventions
Bavelier, D., Levi, D. M., Li, R. W., Dan, Y., & Hensch, T. K. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4812-10.2010 · Cited by 589 · see citing works
Levin, L. A., NILSSON, S. F. E., Hoeve, J. N. V., Wu, S. M.-S., Kaufman, P. L., & Alm, A. (2011) · Andalas University Repository (Andalas University) · Cited by 578 · see citing works
Visual categorization shapes feature selectivity in the primate temporal cortex
Sigala, N., & Logothetis, N. K. (2002) · Nature · doi:10.1038/415318a · Cited by 559 · see citing works
Perceptual Learning Directs Auditory Cortical Map Reorganization through Top-Down Influences
Polley, D. B., Steinberg, E. E., & Merzenich, M. M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3771-05.2006 · Cited by 551 · see citing works
Information-limiting correlations
Moreno‐Bote, R., Beck, J. M., Kanitscheider, I., Pitkow, X., Latham, P. E., & Pouget, A. (2014) · Nature Neuroscience · doi:10.1038/nn.3807 · Cited by 541 · see citing works
Dosher, B. A., & Lu, Z. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.23.13988 · Cited by 527 · see citing works
Perceptual learning and top-down influences in primary visual cortex
Li, W., Piëch, V., & Gilbert, C. D. (2004) · Nature Neuroscience · doi:10.1038/nn1255 · Cited by 474 · see citing works
Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Braun, A., Bruckmann, A., Gekeler, F., Greppmaier, U., Hipp, S., Hörtdörfer, G., Kernstock, C., et al. (2013) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2013.0077 · Cited by 473 · see citing works
Perceptual learning in Vision Research
Sagi, D. (2010) · Vision Research · doi:10.1016/j.visres.2010.10.019 · Cited by 435 · see citing works
The Effect of Perceptual Learning on Neuronal Responses in Monkey Visual Area V4
Yang, T., & Maunsell, J. H. R. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4442-03.2004 · Cited by 427 · see citing works
McLaughlin, T., Torborg, C. L., Feller, M. B., & O'Leary, D. D. M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00790-6 · Cited by 422 · see citing works
Complete Transfer of Perceptual Learning across Retinal Locations Enabled by Double Training
Xiao, L.-Q., Zhang, J.-Y., Wang, R., Klein, S. A., Levi, D. M., & Yu, C. (2008) · Current Biology · doi:10.1016/j.cub.2008.10.030 · Cited by 414 · see citing works
Applications of prism adaptation: a tutorial in theory and method
Redding, G. M., Rossetti, Y., & Wallace, B. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.12.004 · Cited by 413 · see citing works
Movshon, J. A., & Sluyters, R. C. V. (1981) · Annual Review of Psychology · doi:10.1146/annurev.ps.32.020181.002401 · Cited by 410 · see citing works
Vision without inversion of the retinal image.
Stratton, G. M. (1897) · Psychological Review · doi:10.1037/h0071173 · Cited by 406 · see citing works
Stereopsis and amblyopia: A mini-review
Levi, D. M., Knill, D. C., & Bavelier, D. (2015) · Vision Research · doi:10.1016/j.visres.2015.01.002 · Cited by 405 · see citing works
Otx2 Binding to Perineuronal Nets Persistently Regulates Plasticity in the Mature Visual Cortex
Beurdeley, M., Spatazza, J., Lee, H. H. C., Sugiyama, S., Bernard, C., Di Nardo, A. A., Hensch, T. K., & Prochiantz, A. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0394-12.2012 · Cited by 398 · see citing works
Neural correlates of perceptual learning: A functional MRI study of visual texture discrimination
Schwartz, S., Maquet, P., & Frith, C. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.242414599 · Cited by 388 · see citing works
Subretinal visual implant alpha IMS - clinical trial interim report
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Chee, C. K., Cottriall, C. L., Gekeler, F., Groppe, M., Jackson, T. L., MacLaren, R. E., Koitschev, A., et al. (2015) · Vision Research · doi:10.1016/j.visres.2015.03.001 · Cited by 387 · see citing works
Mohler, C. W., & Wurtz, R. H. (1977) · Journal of Neurophysiology · doi:10.1152/jn.1977.40.1.74 · Cited by 383 · see citing works
Zeitz, C., Robson, A. G., & Audo, I. S. (2014) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2014.09.001 · Cited by 377 · see citing works
Visual behaviour mediated by retinal projections directed to the auditory pathway
von Melchner, L., Pallas, S. L., & Sur, M. (2000) · Nature · doi:10.1038/35009102 · Cited by 371 · see citing works
Learning to see: experience and attention in primary visual cortex
Crist, R. E., Li, W., & Gilbert, C. D. (2001) · Nature Neuroscience · doi:10.1038/87470 · Cited by 364 · see citing works
Microstimulation of inferotemporal cortex influences face categorization
Afraz, S.-R., Kiani, R., & Esteky, H. (2006) · Nature · doi:10.1038/nature04982 · Cited by 363 · see citing works
da Cruz, L., Coley, B. F., Dorn, J., Merlini, F., Filley, E., Christopher, P., Chen, F. K., Wuyyuru, V., Sahel, J., Stanga, P., et al. (2013) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2012-301525 · Cited by 359 · see citing works
Five-year safety and performance results from the argus II retinal prosthesis system clinical trial.
da Cruz, L., Dorn, J. D., Humayun, M. S., Dagnelie, G., Handa, J., Barale, P.-O., Sahel, J.-A., Stanga, P. E., Hafezi, F., Safran, A. B., et al. (2016) · Ophthalmology · doi:10.1016/j.ophtha.2016.06.049 · Cited by 359 · see citing works
Age in the development of closure ability in children.
Mooney, C. M. (1957) · Canadian Journal of Psychology/Revue Canadienne de Psychologie · doi:10.1037/h0083717 · Cited by 348 · see citing works
Photovoltaic restoration of sight with high visual acuity
Lorach, H., Goetz, G., Smith, R., Lei, X., Mandel, Y., Kamins, T. I., Mathieson, K., Huie, P., Harris, J. S., Sher, A., et al. (2015) · Nature Medicine · doi:10.1038/nm.3851 · Cited by 341 · see citing works
First-in-human trial of a novel suprachoroidal retinal prosthesis
Ayton, L. N., Blamey, P. J., Guymer, R. H., Luu, C. D., Nayagam, D. A. X., Sinclair, N. C., Shivdasani, M. N., Yeoh, J., McCombe, M. F., Briggs, R. J., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115239 · Cited by 333 · see citing works
Effects of Shape-Discrimination Training on the Selectivity of Inferotemporal Cells in Adult Monkeys
Kobatake, E., Wang, G., & Tanaka, K. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.1.324 · Cited by 329 · see citing works
The Dynamics of Perceptual Learning: An Incremental Reweighting Model.
Petrov, A. A., Dosher, B. A., & Lu, Z. (2005) · Psychological Review · doi:10.1037/0033-295x.112.4.715 · Cited by 313 · see citing works
Physiological Correlates of Perceptual Learning in Monkey V1 and V2
Ghose, G. M., Yang, T., & Maunsell, J. H. R. (2002) · Journal of Neurophysiology · doi:10.1152/jn.00690.2001 · Cited by 310 · see citing works
Long-term deprivation affects visual perception and cortex
Fine, I., Wade, A. R., Brewer, A. A., May, M. G., Goodman, D. F., Boynton, G. M., Wandell, B. A., & MacLeod, D. I. A. (2003) · Nature Neuroscience · doi:10.1038/nn1102 · Cited by 309 · see citing works
Self-citationTopographic reorganization in the striate cortex of the adult cat and monkey is cortically mediated
Darian‐Smith, C., & Gilbert, C. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-03-01631.1995 · Cited by 306 · see citing works
Video-Game Play Induces Plasticity in the Visual System of Adults with Amblyopia
Li, R. W., Ngo, C. V., Nguyen, J., & Levi, D. M. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001135 · Cited by 305 · see citing works
Learning Strengthens the Response of Primary Visual Cortex to Simple Patterns
Furmanski, C. S., Schluppeck, D., & Engel, S. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.03.032 · Cited by 286 · see citing works
Reorganization of Visual Processing in Macular Degeneration
Baker, C. I., Eli Peli, A., Knouf, N. A., & Kanwisher, N. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3476-04.2005 · Cited by 285 · see citing works
Developmental mechanisms of topographic map formation and alignment
Cang, J., & Feldheim, D. A. (2013) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062012-170341 · Cited by 275 · see citing works
Recanzone, G. H., Merzenich, M. M., & Jenkins, W. M. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.67.5.1057 · Cited by 268 · see citing works
Retinal Remodeling in Inherited Photoreceptor Degenerations
Marc, R. E., & Jones, B. W. (2003) · Molecular Neurobiology · doi:10.1385/mn:28:2:139 · Cited by 258 · see citing works
Dynamic Changes in Brain Activity during Prism Adaptation
Luauté, J., Schwartz, S., Rossetti, Y., Spiridon, M., Gilles Rode, A., Dominique Boisson, A., & Vuilleumier, P. O. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3054-08.2009 · Cited by 245 · see citing works
Comparing perceptual learning across tasks: A review
Fine, I., & Jacobs, R. A. (2002) · Journal of Vision · doi:10.1167/2.2.5 · Cited by 242 · see citing works
Self-citationOptogenetic therapy for retinitis pigmentosa
Busskamp, V., Picaud, S. A., Sahel, J., & Roska, B. (2011) · Gene Therapy · doi:10.1038/gt.2011.155 · Cited by 237 · see citing works
Rule-Based Learning Explains Visual Perceptual Learning and Its Specificity and Transfer
Zhang, J.-Y., Zhang, G., Xiao, L.-Q., Klein, S. A., Levi, D. M., & Yu, C. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0704-10.2010 · Cited by 236 · see citing works
Visual hallucinations as release phenomena
Cogan, D. G. (1973) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/bf00407835 · Cited by 234 · see citing works
Critical Period Mechanisms in Developing Visual Cortex
Hensch, T. K. (2005) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(05)69008-4 · Cited by 226 · see citing works
Artificial vision: needs, functioning, and testing of a retinal electronic prosthesis
Chader, G. J., Weiland, J. D., & Humayun, M. S. (2009) · Progress in brain research · doi:10.1016/s0079-6123(09)17522-2 · Cited by 226 · see citing works
Rangarajan, V., Hermes, D., Foster, B. L., Weiner, K. S., Jacques, C., Grill-Spector, K., & Parvizi, J. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0527-14.2014 · Cited by 226 · see citing works
Beckers, G., & Hömberg, V. (1992) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1992.0100 · Cited by 226 · see citing works
Lack of long-term cortical reorganization after macaque retinal lesions
Smirnakis, S. M., Brewer, A. A., Schmid, M. C., Tolias, A. S., Schüz, A., Augath, M. A., INHOFFEN, W., Wandell, B. A., & Logothetis, N. K. (2005) · Nature · doi:10.1038/nature03495 · Cited by 220 · see citing works
Role of emergent neural activity in visual map development
Ackman, J. B., & Crair, M. C. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.11.011 · Cited by 219 · see citing works
Collignon, O., Dormal, G., Albouy, G., Vandewalle, G., Voss, P., Phillips, C. L. M., & Leporé, F. (2013) · Brain · doi:10.1093/brain/awt176 · Cited by 218 · see citing works
Recanzone, G. H., Jenkins, W. M., Hradek, G. T., & Merzenich, M. M. (1992) · Journal of Neurophysiology · doi:10.1152/jn.1992.67.5.1015 · Cited by 215 · see citing works
Experience-Dependent Plasticity in Adult Visual Cortex
Karmarkar, U. R., & Dan, Y. (2006) · Neuron · doi:10.1016/j.neuron.2006.11.001 · Cited by 208 · see citing works
Grubb, M. S., Rossi, F. M., Changeux, J.-P., & Thompson, I. D. (2003) · Neuron · doi:10.1016/s0896-6273(03)00789-x · Cited by 208 · see citing works
Plasticity and stability of visual field maps in adult primary visual cortex
Wandell, B. A., & Smirnakis, S. M. (2009) · Nature reviews. Neuroscience · doi:10.1038/nrn2741 · Cited by 204 · see citing works
Learning-induced plasticity in animal and human auditory cortex
Ohl, F. W., & Scheich, H. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.07.002 · Cited by 196 · see citing works
Demonstration of artificial visual percepts generated through thalamic microstimulation
Pezaris, J. S., & Reid, R. C. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608563104 · Cited by 195 · see citing works
Functional connectivity of visual cortex in the blind follows retinotopic organization principles
Striem-Amit, E., Ovadia-Caro, S., Caramazza, A., Margulies, D. S., Villringer, A., & Amedi, A. (2015) · Brain · doi:10.1093/brain/awv083 · Cited by 194 · see citing works
Rapid axonal sprouting and pruning accompany functional reorganization in primary visual cortex
Yamahachi, H., Marik, S. A., McManus, J. N. J., Denk, W., & Gilbert, C. D. (2009) · Neuron · doi:10.1016/j.neuron.2009.11.026 · Cited by 193 · see citing works
Large-scale remapping of visual cortex is absent in adult humans with macular degeneration
Baseler, H. A., Gouws, A. D., Haak, K. V., Racey, C., Crossland, M. D., Tufail, A., Rubin, G. S., Cornelissen, F. W., & Morland, A. B. (2011) · Nature Neuroscience · doi:10.1038/nn.2793 · Cited by 193 · see citing works
Perceptual learning in contrast discrimination and the (minimal) role of context
Yu, C., Klein, S. A., & Levi, D. M. (2004) · Journal of Vision · doi:10.1167/4.3.4 · Cited by 192 · see citing works
Sengupta, A., Chaffiol, A., Macé, É., Caplette, R., Desrosiers, M., Lampič, M., Forster, V., Marre, O., Lin, J. Y., Sahel, J., et al. (2016) · EMBO Molecular Medicine · doi:10.15252/emmm.201505699 · Cited by 180 · see citing works
Dorn, J. D., Ahuja, A. K., Caspi, A., da Cruz, L., Dagnelie, G., Sahel, J.-A., Greenberg, R. J., McMahon, M. J., & Argus II Study Group, F. T. (2013) · JAMA Ophthalmology · doi:10.1001/2013.jamaophthalmol.221 · Cited by 177 · see citing works
Context-enabled learning in the human visual system
Adini, Y., Sagi, D., & Tsodyks, M. V. (2002) · Nature · doi:10.1038/415790a · Cited by 175 · see citing works
Three remarks on perceptual learning
Mollon, J. D., & Danilova, M. V. (1996) · Spatial Vision · doi:10.1163/156856896x00051 · Cited by 175 · see citing works
Reorganization of human cortical maps caused by inherited photoreceptor abnormalities
Baseler, H. A., Brewer, A. A., Sharpe, L. T., Morland, A. B., Jägle, H., & Wandell, B. A. (2002) · Nature Neuroscience · doi:10.1038/nn817 · Cited by 172 · see citing works
Ephrin-As Guide the Formation of Functional Maps in the Visual Cortex
Cang, J., Kaneko, M., Yamada, J., Woods, G., Stryker, M. P., & Feldheim, D. A. (2005) · Neuron · doi:10.1016/j.neuron.2005.10.026 · Cited by 171 · see citing works
Perceptual image quality assessment using a normalized Laplacian pyramid
Laparra, V., Ballé, J., Berardino, A., & Simoncelli, E. P. (2016) · Electronic Imaging · doi:10.2352/issn.2470-1173.2016.16.hvei-103 · Cited by 166 · see citing works
Improving Reading Speed for People with Central Vision Loss through Perceptual Learning
Chung, S. T. L. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6034 · Cited by 160 · see citing works
Perceptual Learning Selectively Refines Orientation Representations in Early Visual Cortex
Jehee, J. F. M., Ling, S., Swisher, J. D., van Bergen, R. S., & Tong, F. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.6112-11.2012 · Cited by 156 · see citing works
Petralia, R. S., Wang, Y., Zhao, H.-M., & Wenthold, R. J. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960826)372:3 · Cited by 156 · see citing works
Valproate reopens critical-period learning of absolute pitch
Gervain, J., Vines, B. W., Chen, L. M., Seo, R. J., Hensch, T. K., Werker, J. F., & Young, A. H. (2013) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2013.00102 · Cited by 151 · see citing works
Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity
Gaub, B. M., Berry, M. H., Holt, A., Isacoff, E. Y., & Flannery, J. G. (2015) · Molecular Therapy · doi:10.1038/mt.2015.121 · Cited by 148 · see citing works
Genotype and Phenotype of 101 Dutch Patients with Congenital Stationary Night Blindness
Bijveld, M. M. C., Florijn, R. J., Bergen, A. A. B., van den Born, L. I., Kamermans, M., Wenniger-Prick, L. J. J. M. M. D. B., Riemslag, F. C. C., van Schooneveld, M. J., Kappers, A. M. L., & van Genderen, M. M. (2013) · Ophthalmology · doi:10.1016/j.ophtha.2013.03.002 · Cited by 146 · see citing works
Di, C., Liao, S., Adamson, D. C., Parrett, T. J., Broderick, D. K., Shi, Q., Christoph Lengauer, C., Cummins, J. M., Velculescu, V. E., Fults, D. W., et al. (2005) · Cancer Research · doi:10.1158/0008-5472.919.65.3 · Cited by 144 · see citing works
V1 Projection Zone Signals in Human Macular Degeneration Depend on Task, not Stimulus
Masuda, Y., Dumoulin, S. O., Nakadomari, S., & Wandell, B. A. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm256 · Cited by 144 · see citing works
Perceptual learning in vernier acuity: What is learned?
Saarinen, J. K. S., & Levi, D. M. (1995) · Vision Research · doi:10.1016/0042-6989(94)00141-8 · Cited by 143 · see citing works
Effects of perceptual learning on primary visual cortex activity in humans
Pourtois, G., Rauss, K. S., Vuilleumier, P. O., & Schwartz, S. (2007) · Vision Research · doi:10.1016/j.visres.2007.10.027 · Cited by 138 · see citing works
New concepts concerning the neural mechanisms of amblyopia and their clinical implications
WONG, A. M. F. (2012) · Canadian Journal of Ophthalmology · doi:10.1016/j.jcjo.2012.05.002 · Cited by 138 · see citing works
A quantitative measure for short-term cortical plasticity in human vision
Kapadia, M., Gilbert, C., & Westheimer, G. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-01-00451.1994 · Cited by 137 · see citing works
The filling-in process in patients with retinal scotomata
Gerrits, H. J. M., & Timmerman, G. J. M. E. N. (1969) · Vision Research · doi:10.1016/0042-6989(69)90092-3 · Cited by 135 · see citing works
Organization of the Visual Cortex in Human Albinism
Hoffmann, M. B., Tolhurst, D. J., Moore, A. T., & Morland, A. B. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-26-08921.2003 · Cited by 135 · see citing works
Visual Motion Area MT+/V5 Responds to Auditory Motion in Human Sight-Recovery Subjects
Sàenz, M., Lewis, L. B., Huth, A. G., Fine, I., & Christof Koch, A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0803-08.2008 · Cited by 134 · see citing works
Self-citationBaker, C. I., Dilks, D. D., Eli Peli, A., & Kanwisher, N. (2008) · Vision Research · doi:10.1016/j.visres.2008.05.020 · Cited by 133 · see citing works
Effect of dark-rearing on experimental myopia in monkeys.
Raviola, E., & Wiesel, T. N. (1978) · PubMed · Cited by 132 · see citing works
Can visual function be restored in patients with homonymous hemianopia?
Pambakian, A., & Kennard, C. (1997) · British Journal of Ophthalmology · doi:10.1136/bjo.81.4.324 · Cited by 132 · see citing works
The “EyeCane”, a new electronic travel aid for the blind: Technology, behavior & swift learning
Maidenbaum, S., Hanassy, S., Abboud, S., Buchs, G., Chebat, D., Levy‐Tzedek, S., & Amedi, A. (2014) · Restorative Neurology and Neuroscience · doi:10.3233/rnn-130351 · Cited by 129 · see citing works
Visual Parsing After Recovery From Blindness
Ostrovsky, Y., Meyers, E. M., Ganesh, S., Mathur, U., & Sinha, P. (2009) · Psychological Science · doi:10.1111/j.1467-9280.2009.02471.x · Cited by 125 · see citing works
Holistic Processing of Faces: Learning Effects with Mooney Faces
Latinus, M., & Taylor, M. J. (2005) · Journal of Cognitive Neuroscience · doi:10.1162/0898929055002490 · Cited by 124 · see citing works
Dilks, D. D., Baker, C. I., Eli Peli, A., & Kanwisher, N. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5258-08.2009 · Cited by 117 · see citing works
Horton, J. C., & Hocking, D. R. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-14-05433.1998 · Cited by 114 · see citing works
Early Specification of the Hierarchical Organization of Visual Cortical Areas in the Macaque Monkey
Batardière, A. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.5.453 · Cited by 113 · see citing works
Filling-in of retinal scotomas
Zur, D., & Ullman, S. (2003) · Vision Research · doi:10.1016/s0042-6989(03)00038-5 · Cited by 113 · see citing works
The Puzzle of Visual Development: Behavior and Neural Limits
Kiorpes, L. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.2937-16.2016 · Cited by 112 · see citing works
Krupinski, E. A., Graham, A. R., & Weinstein, R. S. (2012) · Human Pathology · doi:10.1016/j.humpath.2012.05.024 · Cited by 110 · see citing works
Perceiving electrical stimulation of identified human visual areas
Murphey, D. K., Maunsell, J. H. R., Beauchamp, M. S., & Yoshor, D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804998106 · Cited by 109 · see citing works
Li, R. W., Klein, S. A., & Levi, D. M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4271-08.2008 · Cited by 108 · see citing works
Development of pattern vision following early and extended blindness
Kalia, A., Lesmes, L. A., Dorr, M., Gandhi, T., Chatterjee, G., Ganesh, S., Bex, P. J., & Sinha, P. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1311041111 · Cited by 106 · see citing works
Form representation in monkey inferotemporal cortex is virtually unaltered by free viewing
DiCarlo, J. J., & Maunsell, J. H. R. (2000) · Nature Neuroscience · doi:10.1038/77722 · Cited by 102 · see citing works
Fujikado, T., Kamei, M., Sakaguchi, H., Kanda, H., Endo, T., Hirota, M., Morimoto, T., Nishida, K., Kishima, H., Terasawa, Y., et al. (2016) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.16-20367 · Cited by 101 · see citing works
Navigation using sensory substitution in real and virtual mazes
Chebat, D.-R., Maidenbaum, S., & Amedi, A. (2015) · PLOS ONE · doi:10.1371/journal.pone.0126307 · Cited by 99 · see citing works
Human Adult Cortical Reorganization and Consequent Visual Distortion
Dilks, D. D., Serences, J. T., Tamber-Rosenau, B. J., Yantis, S., & McCloskey, M. E. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2650-07.2007 · Cited by 97 · see citing works
Brightness as a Function of Current Amplitude in Human Retinal Electrical Stimulation
Greenwald, S. H., Horsager, A., Humayun, M. S., Greenberg, R. J., McMahon, M. J., & Fine, I. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-2897 · Cited by 95 · see citing works
Self-citationDagnelie, G., Christopher, P., Arditi, A. R., da Cruz, L., Duncan, J. L., Ho, A. C., de Koo, L. C. O., Sahel, J., Stanga, P. E., Thumann, G., et al. (2016) · Clinical and Experimental Ophthalmology · doi:10.1111/ceo.12812 · Cited by 93 · see citing works
Bilateral visual field maps in a patient with only one hemisphere
Muckli, L. F., Naumer, M. J., & Singer, W. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809688106 · Cited by 90 · see citing works
Striate cortex lesions and visual acuity of the rhesus monkey.
Weiskrantz, L., & Cowey, A. (1963) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0043778 · Cited by 85 · see citing works
Task relevancy and demand modulate double-training enabled transfer of perceptual learning
Wang, R., Zhang, J.-Y., Klein, S. A., Levi, D. M., & Yu, C. (2011) · Vision Research · doi:10.1016/j.visres.2011.07.019 · Cited by 85 · see citing works
Maidenbaum, S., Levy‐Tzedek, S., Chebat, D., & Amedi, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072555 · Cited by 84 · see citing works
Plasticity and Stability of the Visual System in Human Achiasma
Hoffmann, M. B., Kaule, F. R., Levin, N., Masuda, Y., Kumar, A., Gottlob, I., Horiguchi, H., Dougherty, R. F., Stadler, J., Wolynski, B., et al. (2012) · Neuron · doi:10.1016/j.neuron.2012.05.026 · Cited by 84 · see citing works
Phosphene induction by microstimulation of macaque V1
Tehovnik, E. J., & Slocum, W. M. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.11.001 · Cited by 83 · see citing works
Retinal prostheses: progress toward the next generation implants
Ghezzi, D. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00290 · Cited by 83 · see citing works
The Argus II Retinal Prosthesis: 12-Month Outcomes from a Single-Study Center
Rizzo, S., Belting, C., Cinelli, L., Allegrini, L., Genovesi-Ebert, F., Barca, F., & Bartolo, E. D. (2014) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2014.02.039 · Cited by 83 · see citing works
Developmental Remodeling of Primate Visual Cortical Pathways
Barone, P., Dehay, C., Berland, M., Bullier, J., & Kennedy, H. (1995) · Cerebral Cortex · doi:10.1093/cercor/5.1.22 · Cited by 82 · see citing works
Therapeutic potential of valproic acid for retinitis pigmentosa
Clemson, C., Tzekov, R. T., Krebs, M. P., Checchi, J., Bigelow, C., & Kaushal, S. (2010) · British Journal of Ophthalmology · doi:10.1136/bjo.2009.175356 · Cited by 82 · see citing works
Relearning to See in Cortical Blindness
Melnick, M. D., Tadin, D., & Huxlin, K. R. (2015) · The Neuroscientist · doi:10.1177/1073858415621035 · Cited by 82 · see citing works
Advances in auditory prostheses
Shannon, R. V. (2011) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32834ef878 · Cited by 81 · see citing works
The limits of shape recognition following late emergence from blindness
McKyton, A., Ben-Zion, I., Doron, R., & Zohary, E. (2015) · Current Biology · doi:10.1016/j.cub.2015.06.040 · Cited by 79 · see citing works
Learning Increases Stimulus Salience in Anterior Inferior Temporal Cortex of the Macaque
Jagadeesh, B., Chelazzi, L., Mishkin, M., & Desimone, R. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.1.290 · Cited by 76 · see citing works
Advances in gene therapy technologies to treat retinitis pigmentosa
Petrs‐Silva, H., & Linden, R. (2013) · Clinical ophthalmology · doi:10.2147/opth.s38041 · Cited by 75 · see citing works
Pixium Vision: First Clinical Results and Innovative Developments
Hornig, R., Dapper, M., Joliff, E. L., Hill, R. G., Ishaque, K., Posch, C., Benosman, R. B., Mer, Y. L., Sahel, J., & Picaud, S. A. (2016) · Springer eBooks · doi:10.1007/978-3-319-41876-6_8 · Cited by 73 · see citing works
Microstimulation Reveals Limits in Detecting Different Signals from a Local Cortical Region
Ni, A. M., & Maunsell, J. H. R. (2010) · Current Biology · doi:10.1016/j.cub.2010.02.065 · Cited by 73 · see citing works
Binda, P., Thomas, J. M., Boynton, G. M., & Fine, I. (2013) · Journal of Vision · doi:10.1167/13.7.13 · Cited by 70 · see citing works
Self-citationVisual BOLD Response in Late Blind Subjects with Argus II Retinal Prosthesis
Castaldi, E., Cicchini, G. M., Cinelli, L., Biagi, L., Rizzo, S., & Morrone, M. C. (2016) · PLoS Biology · doi:10.1371/journal.pbio.1002569 · Cited by 69 · see citing works
Broad-based visual benefits from training with an integrated perceptual-learning video game
Deveau, J., Lovcik, G., & Seitz, A. R. (2014) · Vision Research · doi:10.1016/j.visres.2013.12.015 · Cited by 67 · see citing works
Resting-State Retinotopic Organization in the Absence of Retinal Input and Visual Experience
Bock, A., Binda, P., Benson, N. C., Bridge, H., Watkins, K. E., & Fine, I. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4715-14.2015 · Cited by 66 · see citing works
Self-citationWang, R., Zhang, J.-Y., Klein, S. A., Levi, D. M., & Yu, C. (2014) · Journal of Vision · doi:10.1167/14.13.12 · Cited by 66 · see citing works
Calford, M. B., Chino, Y. M., Das, A., Eysel, U. T., Gilbert, C. D., Heinen, S. J., Kaas, J. H., & Ullman, S. (2005) · Nature · doi:10.1038/nature04359 · Cited by 65 · see citing works
Cortical Reorganization after Long-Term Adaptation to Retinal Lesions in Humans
Chung, S. T. L. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2764-13.2013 · Cited by 65 · see citing works
Upright Vision and the Retinal Image.
Stratton, G. M. (1897) · Psychological Review · doi:10.1037/h0064110 · Cited by 65 · see citing works
Rokem, A., Landau, A. N., Garg, D., Prinzmetal, W., & Silver, M. A. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.118 · Cited by 65 · see citing works
Self-citationA Lack of Experience-Dependent Plasticity After More Than a Decade of Recovered Sight
Huber, E., Webster, J. M., Brewer, A. A., MacLeod, D. I. A., Wandell, B. A., Boynton, G. M., Wade, A. R., & Fine, I. (2015) · Psychological Science · doi:10.1177/0956797614563957 · Cited by 63 · see citing works
Self-citationDjourno, Eyries, and the First Implanted Electrical Neural Stimulator to Restore Hearing
Eisen, M. D. (2003) · Otology & Neurotology · doi:10.1097/00129492-200305000-00025 · Cited by 61 · see citing works
Living with cochlear implants: experiences of 17 adult patients in Sweden
Hallberg, L. R. ‐., & Ringdahl, A. (2004) · International Journal of Audiology · doi:10.1080/14992020400050016 · Cited by 59 · see citing works
Orientation tuning for disparity defined edges in Macaque V2
Bredfeldt, C. E., & Cumming, B. G. (2004) · Journal of Vision · doi:10.1167/4.8.169 · Cited by 59 · see citing works
Spatazza, J., Lullo, E. D., Joliot, A., Dupont, E., Moya, K. L., & Prochiantz, A. (2013) · Pharmacological Reviews · doi:10.1124/pr.112.006577 · Cited by 58 · see citing works
Contrast masking effects change with practice
Dorais, A., & Sagi, D. (1997) · Vision Research · doi:10.1016/s0042-6989(96)00329-x · Cited by 57 · see citing works
Saunders, A. L., Williams, C. E., Heriot, W. J., Briggs, R., Yeoh, J., Nayagam, D. A. X., McCombe, M. F., Villalobos, J., Burns, O., Luu, C. D., et al. (2013) · Clinical and Experimental Ophthalmology · doi:10.1111/ceo.12287 · Cited by 56 · see citing works
Task-Dependent V1 Responses in Human Retinitis Pigmentosa
Masuda, Y., Horiguchi, H., Dumoulin, S. O., Furuta, A., Miyauchi, S., Nakadomari, S., & Wandell, B. A. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.09-4775 · Cited by 56 · see citing works
Fine, I., & Boynton, G. M. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2014.0208 · Cited by 55 · see citing works
Self-citationPrimary visual cortical remapping in patients with inherited peripheral retinal degeneration
Ferreira, S., Pereira, A. C., Quendera, B., Reis, A., Silva, E. D., & Castelo-Branco, M. S. (2016) · NeuroImage Clinical · doi:10.1016/j.nicl.2016.12.013 · Cited by 55 · see citing works
The benefits of cholinergic enhancement during perceptual learning are long-lasting
Rokem, A., & Silver, M. A. (2013) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2013.00066 · Cited by 53 · see citing works
Self-citationEvolution of the circuitry for conscious color vision in primates
Jay Neitz, A., & Neitz, M. (2016) · Eye · doi:10.1038/eye.2016.257 · Cited by 52 · see citing works
What are the mechanisms of photoreceptor adaptation?
Bownds, M. D., & Arshavsky, V. Y. (1995) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00039170 · Cited by 51 · see citing works
Worldwide Argus II implantation: recommendations to optimize patient outcomes
Ghodasra, D. H., Chen, A., Arévalo, J. F., Birch, D. G., Branham, K. E. H., Coley, B., Dagnelie, G., de Juan, E., Devenyi, R. G., Dorn, J. D., et al. (2016) · BMC Ophthalmology · doi:10.1186/s12886-016-0225-1 · Cited by 50 · see citing works
Neurobiological hypothesis of color appearance and hue perception
Schmidt, B. P., Neitz, M., & Neitz, J. (2014) · Journal of the Optical Society of America A · doi:10.1364/josaa.31.00a195 · Cited by 49 · see citing works
Daye, P. M., Blohm, G., & Lefèvre, P. (2014) · Journal of Vision · doi:10.1167/14.1.12 · Cited by 49 · see citing works
He, Y., Legge, G. E., & Yu, D. (2013) · Journal of Vision · doi:10.1167/13.7.14 · Cited by 47 · see citing works
Cortical and subcortical connections of V1 and V2 in early postnatal macaque monkeys
Baldwin, M. K. L., Kaskan, P. M., Zhang, B., Chino, Y. M., & Kaas, J. H. (2011) · The Journal of Comparative Neurology · doi:10.1002/cne.22732 · Cited by 47 · see citing works
Is peripheral visual acuity susceptible to perceptual learning in the adult?
Westheimer, G. (2001) · Vision Research · doi:10.1016/s0042-6989(00)00245-5 · Cited by 47 · see citing works
Spatial frequency masking and Weber's Law
Swift, D. J., & Smith, R. A. (1983) · Vision Research · doi:10.1016/0042-6989(83)90124-4 · Cited by 47 · see citing works
Large-Scale Axonal Reorganization of Inhibitory Neurons following Retinal Lesions
Marik, S. A., Yamahachi, H., Borgloh, S. M. Z. A., & Gilbert, C. D. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4345-13.2014 · Cited by 45 · see citing works
Rosa, M. G. P., Schmid, L. M., & Calford, M. B. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp020543 · Cited by 42 · see citing works
Visual function before and after the removal of bilateral congenital cataracts in adulthood
Fine, I., Smallman, H. S., Doyle, P. G., & MacLeod, D. I. A. (2002) · Vision Research · doi:10.1016/s0042-6989(01)00266-8 · Cited by 41 · see citing works
Self-citationPerceptual learning for a pattern discrimination task
Fine, I., & Jacobs, R. A. (2000) · Vision Research · doi:10.1016/s0042-6989(00)00163-2 · Cited by 41 · see citing works
Self-citationBachatene, L., Bharmauria, V., Cattan, S., & Molotchnikoff, S. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12206 · Cited by 39 · see citing works
Visual activity and cortical rewiring: activity-dependent plasticity of cortical networks
Horng, S. H., & Sur, M. (2006) · Progress in brain research · doi:10.1016/s0079-6123(06)57001-3 · Cited by 38 · see citing works
The geometric structure of color
Logvinenko, A. D. (2015) · Journal of Vision · doi:10.1167/15.1.16 · Cited by 37 · see citing works
One Picture Is Worth at Least a Million Neurons
Levy, I., Hasson, U., & Malach, R. (2004) · Current Biology · doi:10.1016/j.cub.2004.05.045 · Cited by 36 · see citing works
Adaptation, perceptual learning, and plasticity of brain functions
Horton, J. C., Fahle, M. W., Mulder, T. W., & Trauzettel‐Klosinski, S. (2017) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-016-3580-y · Cited by 36 · see citing works
Sachse, P., Beermann, U., Martini, M., Maran, T. K., Domeier, M., & Furtner, M. R. (2017) · Cortex · doi:10.1016/j.cortex.2017.04.014 · Cited by 36 · see citing works
Higher-contrast requirements for recognizing low-pass-filtered letters
Kwon, M., & Legge, G. E. (2013) · Journal of Vision · doi:10.1167/13.1.13 · Cited by 36 · see citing works
Perception of Graphical Virtual Environments by Blind Users via Sensory Substitution
Maidenbaum, S., Buchs, G., Abboud, S., Lavi‐Rotbain, O., & Amedi, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147501 · Cited by 34 · see citing works
Long-term follow-up for efficacy and safety of treatment of retinitis pigmentosa with valproic acid
Bhalla, S., Joshi, D. D., Bhullar, S. S., Kasuga, D. T., Park, Y., & Kay, C. N. (2013) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2013-303084 · Cited by 32 · see citing works
Efficacy of valproic acid for retinitis pigmentosa patients: a pilot study
Iraha, S., Hirami, Y., Ota, S., Sunagawa, G. A., Mandai, M., Tanihara, H., Takahashi, M., & Kurimoto, Y. (2016) · Clinical ophthalmology · doi:10.2147/opth.s109995 · Cited by 32 · see citing works
Plasticity, and Its Limits, in Adult Human Primary Visual Cortex
Haak, K. V., Haak, K. V., Morland, A. B., Haak, K. V., Morland, A. B., & Engel, S. A. (2015) · Multisensory Research · doi:10.1163/22134808-00002496 · Cited by 31 · see citing works
Talluri, B. C., Hung, S.-C., Seitz, A. R., & Seriès, P. (2015) · Journal of Vision · doi:10.1167/15.10.17 · Cited by 31 · see citing works
Valproic acid treatment may be harmful in non-dominant forms of retinitis pigmentosa: Table 1
Sisk, R. A. (2012) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2012-301950 · Cited by 30 · see citing works
Optimization of perceptual learning: Effects of task difficulty and external noise in older adults
DeLoss, D. J., Watanabe, T., & Andersen, G. J. (2013) · Vision Research · doi:10.1016/j.visres.2013.11.003 · Cited by 30 · see citing works
Rehabilitation Approaches in Macular Degeneration Patients
Maniglia, M., Cottereau, B. R., Soler, V. J., & Trotter, Y. (2016) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2016.00107 · Cited by 30 · see citing works
Chamoun, M., Huppé‐Gourgues, F., Legault, I., Rosa‐Neto, P., Dumbrava, D., Faubert, J., & Vaucher, E. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00128 · Cited by 29 · see citing works
Gamut relativity: A new computational approach to brightness and lightness perception
Vladusich, T. (2013) · Journal of Vision · doi:10.1167/13.1.14 · Cited by 29 · see citing works
Flagged first, then by citations
2 of the 230 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Fine I Smallman HS Doyle PG Macleod DIA 2002b Visual function before and after the removal of congenital bilateral cataracts in adulthood Vision Research 42 191 210 11809473
- Fine I Wade AR Brewer AA May MG Goodman DF Boynton GM Wandell BA Macleod DI 2003b Long-term deprivation affects visual perception and cortex Nat Neurosci 6 915 6 12937420
- Pioneer Press 2015 ‘Bionic eye’ helps Duluth man make out his dark world Twin Cities Pioneer Press
Cited by
Sorted by citations
The Argus® II Retinal Prosthesis System
Luo, Y. H.-L., & da Cruz, L. (2016) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.09.003 · Cited by 351 · see citing works
Dynamic Stimulation of Visual Cortex Produces Form Vision in Sighted and Blind Humans
Beauchamp, M. S., Oswalt, D., Sun, P., Foster, B. L., Magnotti, J. F., Niketeghad, S., Pouratian, N., Bosking, W. H., & Yoshor, D. (2020) · Cell · doi:10.1016/j.cell.2020.04.033 · Cited by 257 · see citing works
“activity pattern that may impair perception (Beyeler et al., 2017).”
An update on retinal prostheses
Ayton, L. N., Barnes, N., Dagnelie, G., Fujikado, T., Goetz, G., Hornig, R., Jones, B. W., Muqit, M. M. K., Rathbun, D. L., Stingl, K., et al. (2020) · Clinical Neurophysiology · doi:10.1016/j.clinph.2019.11.029 · Cited by 223 · see citing works
Advances in retinal prosthesis systems
Bloch, E., Luo, Y., & da Cruz, L. (2019) · Therapeutic Advances in Ophthalmology · doi:10.1177/2515841418817501 · Cited by 201 · see citing works
Neuroplasticity in adult human visual cortex
Castaldi, E., Lunghi, C., & Morrone, M. C. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.02.028 · Cited by 161 · see citing works
A model of ganglion axon pathways accounts for percepts elicited by retinal implants
Beyeler, M., Nanduri, D., Weiland, J. D., Rokem, A., Boynton, G. M., & Fine, I. (2019) · Scientific Reports · doi:10.1038/s41598-019-45416-4 · Cited by 143 · see citing works
Self-citationDevelopment of visual Neuroprostheses: trends and challenges.
Fernandez, E. (2018) · Bioelectronic Medicine · doi:10.1186/s42234-018-0013-8 · Cited by 114 · see citing works
Chenais, N. A. L., Airaghi Leccardi, M. J. I., & Ghezzi, D. (2021) · Communications Materials · doi:10.1038/s43246-021-00133-2 · Cited by 110 · see citing works
Optogenetic restoration of retinal ganglion cell activity in the living primate
McGregor, J. E., Godat, T., Dhakal, K. R., Parkins, K., Strazzeri, J. M., Bateman, B. A., Fischer, W. S., Williams, D. R., & Merigan, W. H. (2020) · Nature Communications · doi:10.1038/s41467-020-15317-6 · Cited by 78 · see citing works
Ayton, L. N., Rizzo, J. F., Bailey, I. L., Colenbrander, A., Dagnelie, G., Geruschat, D. R., Hessburg, P. C., McCarthy, C. D., Petoe, M. A., Rubin, G. S., et al. (2020) · Translational Vision Science & Technology · doi:10.1167/tvst.9.8.25 · Cited by 75 · see citing works
Visual prosthesis: interfacing stimulating electrodes with retinal neurons to restore vision.
Barriga-Rivera, A., Bareket, L., Goding, J., Aregueta-Robles, U. A., & Suaning, G. J. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00620 · Cited by 73 · see citing works
Semantic and structural image segmentation for prosthetic vision
Sanchez-Garcia, M., Martinez-Cantin, R., & Guerrero, J. J. (2020) · PLOS ONE · doi:10.1371/journal.pone.0227677 · Cited by 62 · see citing works
pulse2percept: A Python-based simulation framework for bionic vision
Beyeler, M., Boynton, G., Fine, I., & Rokem, A. (2017) · Proceedings of the 16th Python in Science Conference · doi:10.25080/shinma-7f4c6e7-00c · Cited by 56 · see citing works
Self-citationDeep Learning–Based Scene Simplification for Bionic Vision
Han, N., Srivastava, S., Xu, A., Klein, D., & Beyeler, M. (2021) · Augmented Humans Conference 2021 · doi:10.1145/3458709.3458982 · Cited by 45 · see citing works
Self-citationAdvances in visual prostheses: engineering and biological challenges
Borda, E., & Ghezzi, D. (2022) · Progress in Biomedical Engineering · doi:10.1088/2516-1091/ac812c · Cited by 44 · see citing works
Fernández, E., Alfaro, A., & González-López, P. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00681 · Cited by 35 · see citing works
Brain (re)organization following visual loss
Voss, P. (2018) · Wiley Interdisciplinary Reviews Cognitive Science · doi:10.1002/wcs.1468 · Cited by 39 · see citing works
Beyeler, M., & Sanchez-Garcia, M. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/aca69d · Cited by 34 · see citing works
“One possibility is thus that we must first address fundamental questions about the neural code of vision (Abbasi and Rizzo 2021) and (the lack of) cortical plasticity in adult visual cortex (Beyeler et al 2017), before we can explore AI-based visual augmentations.”
Self-citationThorn, J. T., Migliorini, E., & Ghezzi, D. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abb5bc · Cited by 34 · see citing works
The argus ii retinal prosthesis system
Bloch, E., & da Cruz, L. (2020) · Prosthesis · doi:10.5772/intechopen.84947 · Cited by 31 · see citing works
Simulation of visual perception and learning with a retinal prosthesis
Golden, J. R., Erickson-Davis, C. R., Cottaris, N. P., Parthasarathy, N., Rieke, F. M., Brainard, D. H., Wandell, B. A., & Chichilnisky, E. J. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aaf270 · Cited by 29 · see citing works
Optimization of visual information presentation for visual prosthesis
Guo, F., Yang, Y., & Gao, Y. (2018) · International Journal of Biomedical Imaging · doi:10.1155/2018/3198342 · Cited by 27 · see citing works
A computational model of phosphene appearance for epiretinal prostheses
Granley, J., & Beyeler, M. (2021) · 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) · doi:10.1109/embc46164.2021.9629663 · Cited by 27 · see citing works
Self-citationCortical visual mapping following ocular gene augmentation therapy for achromatopsia
McKyton, A., Averbukh, E., Marks-Ohana, D., Levin, N., & Banin, E. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.3222-20.2021 · Cited by 27 · see citing works
Implications of Neural Plasticity in Retinal Prosthesis
Caravaca-Rodriguez, D., Gaytan, S. P., Suaning, G. J., & Barriga‐Rivera, A. (2022) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.63.11.11 · Cited by 27 · see citing works
pulse2percept: A Python-based simulation framework for bionic visionPreprint
Beyeler, M., Boynton, G. M., Fine, I., & Rokem, A. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/148015 · Cited by 27 · see citing works
Self-citationRasla, A., & Beyeler, M. (2022) · ACM Symposium on Virtual Reality Software and Technology (VRST) · doi:10.1145/3562939.3565620 · Cited by 22 · see citing works
Self-citationMcGregor, J. E., Kunala, K., Xu, Z., Murphy, P. J., Godat, T., Strazzeri, J. M., Bateman, B. A., Fischer, W. S., Parkins, K., Chu, C. J., et al. (2021) · Molecular Therapy · doi:10.1016/j.ymthe.2021.09.014 · Cited by 21 · see citing works
Immersive Virtual Reality Simulations of Bionic Vision
Kasowski, J., & Beyeler, M. (2022) · Augmented Humans 2022 · doi:10.1145/3519391.3522752 · Cited by 18 · see citing works
Self-citationBansal, H., Gupta, N., & Roy, S. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac1175 · Cited by 21 · see citing works
Im, M., & Kim, S. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab8ca9 · Cited by 20 · see citing works
Advances in neuroscience, not devices, will determine the effectiveness of visual prostheses
Abbasi, B., & Rizzo, J. F. (2021) · Seminars in Ophthalmology · doi:10.1080/08820538.2021.1887902 · Cited by 19 · see citing works
Artificial Retina: A Future Cellular-Resolution Brain-Machine Interface
Muratore, D. G., & Chichilnisky, E. J. (2020) · The frontiers collection · doi:10.1007/978-3-030-18338-7_24 · Cited by 19 · see citing works
Italiano, M. L., Guo, T., Lovell, N. H., & Tsai, D. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac72c2 · Cited by 16 · see citing works
Aligning Visual Prosthetic Development With Implantee Needs
Nadolskis, L., Turkstra, L. M., Larnyo, E., & Beyeler, M. (2024) · Translational Vision Science & Technology · doi:10.1167/tvst.13.11.28 · Cited by 16 · see citing works
Self-citationSong, X., Guo, T., Shivdasani, M. N., Dokos, S., Lovell, N. H., Li, X., Qiu, S., Li, T., Zheng, S., & Li, L. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abc3a9 · Cited by 16 · see citing works
Watterson, W. J., Montgomery, R. D., & Taylor, R. P. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00277 · Cited by 16 · see citing works
Neurophysiological considerations for visual implants
Meikle, S. J., & Wong, Y. T. (2022) · Brain Structure and Function · doi:10.1007/s00429-021-02417-2 · Cited by 15 · see citing works
Human-in-the-loop optimization of visual prosthetic stimulation
Fauvel, T., & Chalk, M. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac7615 · Cited by 15 · see citing works
Axonal stimulation affects the linear summation of single-point perception in three Argus II users
Hou, Y., Nanduri, D., Granley, J., Weiland, J. D., & Beyeler, M. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad31c4 · Cited by 14 · see citing works
Self-citationA model of ganglion axon pathways accounts for percepts elicited by retinal implants
Beyeler, M., Nanduri, D., Weiland, J. D., Rokem, A., Boynton, G. M., & Fine, I. (2018) · doi:10.1101/453035 · Cited by 13 · see citing works
Self-citationIndividual variability of neural computations in the primate retina
Shah, N. P., Brackbill, N., Samarakoon, R., Rhoades, C. E., Kling, A., Sher, A., Litke, A. M., Singer, Y., Shlens, J., & Chichilnisky, E. J. (2021) · Neuron · doi:10.1016/j.neuron.2021.11.026 · Cited by 12 · see citing works
Li, H., Zeng, Y., Lu, Z., Cao, X., Su, X., Sui, X., Wang, J., & Chai, X. (2017) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa966d · Cited by 11 · see citing works
Biophysical model of axonal stimulation in epiretinal visual prostheses
Beyeler, M. (2019) · International IEEE/EMBS Conference on Neural Engineering · doi:10.1109/ner.2019.8716969 · Cited by 11 · see citing works
Self-citationOptogenetic activation of visual thalamus generates artificial visual percepts
Wang, J., Azimi, H., Zhao, Y., Kaeser, M., Sánchez, P. V., Vázquez‐Guardado, A., Rogers, J. A., Harvey, M., & Rainer, G. (2023) · eLife · doi:10.7554/elife.90431 · Cited by 10 · see citing works
Raising the stakes for cortical visual prostheses
Beauchamp, M. S., Bosking, W. H., Oswalt, D. N., & Yoshor, D. (2021) · Journal of Clinical Investigation · doi:10.1172/jci154983 · Cited by 9 · see citing works
Prospects of Optogenetic Prosthesis of the Degenerative Retina of the Eye
Оstrovsky, М. А., & Kirpichnikov, M. P. (2019) · Biochemistry (Moscow) · doi:10.1134/s0006297919050031 · Cited by 9 · see citing works
McGregor, J. E. (2019) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2019.10.003 · Cited by 9 · see citing works
Towards Immersive Virtual Reality Simulations of Bionic Vision
Kasowski, J., Wu, N., & Beyeler, M. (2021) · Augmented Humans International Conference (AHs) · doi:10.1145/3458709.3459003 · Cited by 9 · see citing works
Self-citationExplainable machine learning predictions of perceptual sensitivity for retinal prostheses
Pogoncheff, G., Hu, Z., Rokem, A., & Beyeler, M. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad310f · Cited by 9 · see citing works
Self-citationHybrid Neural Autoencoders for Stimulus Encoding in Visual and Other Sensory Neuroprostheses.
Granley, J., Relic, L., & Beyeler, M. (2022) · PubMed · Cited by 8 · see citing works
Self-citationBiologically-inspired image processing in computational retina models
Melanitis, N., & Nikita, K. S. (2019) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2019.103399 · Cited by 8 · see citing works
Residual contrast response in primary visual cortex of rats with inherited retinal degeneration
Chen, K. G., Hou, B., Zhao, Y., Yuan, P., Yao, D., & Chan, L. L. H. (2020) · Vision Research · doi:10.1016/j.visres.2020.08.007 · Cited by 8 · see citing works
Greedy Optimization of Electrode Arrangement for Epiretinal Prostheses
Bruce, A., & Beyeler, M. (2022) · Lecture notes in computer science · doi:10.1007/978-3-031-16449-1_57 · Cited by 8 · see citing works
Self-citationCross-task perceptual learning of object recognition in simulated retinal implant perception
Wang, L., Sharifian, F., Napp, J., Nath, C., & Pollmann, S. (2018) · Journal of Vision · doi:10.1167/18.13.22 · Cited by 8 · see citing works
Roh, H., Otgondemberel, Y., & Im, M. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac8ed7 · Cited by 7 · see citing works
Sensory augmentation to aid training with retinal prostheses
Kvansakul, J. G. S., Hamilton, L. H. W., Ayton, L. N., McCarthy, C. D., & Petoe, M. A. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab9e1d · Cited by 7 · see citing works
Kirpichnikov, M. P., & Оstrovsky, М. А. (2019) · Herald of the Russian Academy of Sciences · doi:10.1134/s1019331619010039 · Cited by 7 · see citing works
Linking Multi-Modal MRI to Clinical Measures of Visual Field Loss After Stroke
Beh, A., McGraw, P. V., Webb, B. S., & Schluppeck, D. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.737215 · Cited by 6 · see citing works
NDE 4.0: Image and Sound Recognition
Hayes, K., & Rajput, A. (2022) · Springer eBooks · doi:10.1007/978-3-030-73206-6_26 · Cited by 5 · see citing works
Learning to see after early and extended blindness: A scoping review
May, E., Arach, P., Kishiki, E., Geneau, R., Maehara, G., Sukhai, M. A., & Hamm, L. M. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.954328 · Cited by 5 · see citing works
Spatiotemporal Pixelization to Increase the Recognition Score of Characters for Retinal Prostheses
Kim, H.-S., & Park, K. S. (2017) · Sensors · doi:10.3390/s17102439 · Cited by 5 · see citing works
Proceedings of the 16th Python in Science Conference
(2017) · doi:10.25080/shinma-7f4c6e7-000 · Cited by 5 · see citing works
Deep Learning--Based Scene Simplification for Bionic Vision
Han, N., Srivastava, S., Xu, A., Klein, D., & Beyeler, M. (2021) · arXiv · doi:10.48550/arxiv.2102.00297 · Cited by 4 · see citing works
Self-citationEsquenazi, R., Meier, K., Beyeler, M., Boynton, G. M., & Fine, I. (2021) · Journal of Vision · doi:10.1167/jov.21.13.10 · Cited by 4 · see citing works
Self-citationLiang, J., Li, H., Chen, J., Zhai, Z., Wang, J., Di, L., & Chai, X. (2022) · Artificial Organs · doi:10.1111/aor.14247 · Cited by 4 · see citing works
TACTILE EDGES AND MOTION VIA PATTERNED MICROSTIMULATION OF THE HUMAN CORTEXPreprint
Valle, G., Alamari, A. H., Lienkämper, R., Downey, J. E., Sobinov, A. R., Endsley, L. J., Prasad, D., Boninger, M. L., Collinger, J. L., Warnke, P. C., et al. (2024) · medRxiv · doi:10.1101/2024.05.06.24306627 · Cited by 4 · see citing works
Hunold, A., Ortega, D., Freitag, S., Link, D., Antal, A., Klee, S., & Haueisen, J. (2025) · Life · doi:10.3390/life15050820 · Cited by 3 · see citing works
Kasowski, J., Varshney, A., Sadeghi, R., & Beyeler, M. (2025) · Journal of Neural Engineering · doi:10.1088/1741-2552/adecc4 · Cited by 3 · see citing works
Self-citationBionic Vision as Neuroadaptive XR: Closed-Loop Perceptual Interfaces for Neurotechnology
Beyeler, M. J. (2025) · IEEE International Symposium on Mixed and Augmented Reality Adjunct (ISMAR-Adjunct) · doi:10.1109/ismar-adjunct68609.2025.00034 · Cited by 4 · see citing works
Self-citationNadvar, N., Stiles, N. R. B., Choupan, J., Patel, V. R., Ameri, H., Shi, Y., Liu, Z., Jonides, J. J., & Weiland, J. D. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.902866 · Cited by 3 · see citing works
Spatiotemporal Pixelization to Increase the Recognition Score of Characters for Retinal Prostheses
Kim, H.-S., & Park, K. S. (2017) · Sensors · doi:10.3390/s17112439 · Cited by 3 · see citing works
RASPV: A Robotics Framework for Augmented Simulated Prosthetic Vision
Pérez-Yus, A., Santos-Villafranca, M., Tomas-Barba, J., Bermúdez-Cameo, J., Montano-Oliván, L., Nicolás, G. L., & Guerrero, J. J. (2024) · IEEE Access · doi:10.1109/access.2024.3357400 · Cited by 3 · see citing works
Human-in-the-loop optimization of visual prosthetic stimulation
Fauvel, T., & Chalk, M. (2021) · doi:10.1101/2021.11.24.469867 · Cited by 15 · see citing works
Moussallem, L., Lombardi, L., McGuinness, M. B., Kolic, M., Baglin, E. K., Jin, R., Habili, N., Kvansakul, J. G. S., Titchener, S. A., Abbott, C. J., et al. (2025) · Journal of Neural Engineering · doi:10.1088/1741-2552/adc83a · Cited by 2 · see citing works
Guo, B. Z., Liu, Y., Cai, W., Suo, Q., & Su, H. (2025) · Medicine · doi:10.1097/md.0000000000043060 · Cited by 2 · see citing works
Jung, Y., Lee, S., Rhee, J. K., Lee, C. E., Baker, B. J., & Song, Y. (2025) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5c00740 · Cited by 2 · see citing works
Kolenik, T. (2018) · Interdisciplinary Description of Complex Systems · doi:10.7906/indecs.16.4.3 · Cited by 2 · see citing works
A scalable data transmission scheme for implantable optogenetic visual prostheses
Hou, Z., Al‐Atabany, W., Farag, R., Vuong, Q. C., Mokhov, A., & Degenaar, P. A. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abaf2e · Cited by 2 · see citing works
Caravaca-Rodriguez, D., Suaning, G. J., & Barriga‐Rivera, A. (2022) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc48229.2022.9871504 · Cited by 2 · see citing works
Beyeler, M. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00471 · Cited by 2 · see citing works
Self-citationMalania, M., Lin, Y.-S., Hörmandinger, C., Werner, J. S., Greenlee, M. W., & Plank, T. (2024) · Journal of Vision · doi:10.1167/jov.24.5.7 · Cited by 1 · see citing works
Saltzmann, S. M., & Stiles, N. R. B. (2025) · Journal of Vision · doi:10.1167/jov.25.12.19 · Cited by 1 · see citing works
Neural population dynamics of direct electrical stimulation of neocortex
Hickman, J. L., Hughes, G., Sahai, E., Miles, M., & Denman, D. J. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117420 · Cited by 1 · see citing works
Fuzzing the brain: automated stress testing for the safety of ML-driven neurostimulation
Downing, M., Peng, M., Granley, J., Beyeler, M., & Bultan, T. (2026) · Journal of Neural Engineering · doi:10.1088/1741-2552/ae4927 · Cited by 1 · see citing works
Self-citationHinrichs, S., Placidet, L., Duret, A., Authié, C., Arleo, A., & Ghezzi, D. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad8b6f · Cited by 1 · see citing works
Modeling fixational eye movement for the vision prosthesis
Rizzo, R., & Seo, J. M. (2019) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2019.8857015
Editorial: A Conversation With the Brain: Can We Speak Its Language?
Barriga‐Rivera, A., Guo, T., Hayashida, Y., & Suaning, G. J. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00794
A Conversation With the Brain: Can We Speak Its Language?
(2020) · Frontiers research topics · doi:10.3389/978-2-88966-067-4
On the potential role of retinal sheet transplants for sight restorationPreprint
Beyeler, M. (2019) · doi:10.31219/osf.io/temqd
Self-citationSimulador inmersivo de visión protésica modelando estímulos espacio-temporales
Santos-Villafranca, M., Tomas-Barba, J., Pérez-Yus, A., Bermúdez-Cameo, J., & Guerrero, J. (2023) · doi:10.17979/spudc.9788497498609.879
NDE 4.0: Image and Sound Recognition
Hayes, K., & Rajput, A. (2025) · Springer eBooks · doi:10.1007/978-3-030-48200-8_26-2
Hinrichs, S., Tisserand, Y., Scialom, E., & Ghezzi, D. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.27.645647
Son, S., Kang, H.-G., Kim, H. R., Shim, W. M., & Lee, J. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.13.648557
NDE 4.0: Image and Sound Recognition
Hayes, K., & Rajput, A. (2025) · Springer eBooks · doi:10.1007/978-3-031-84477-5_26
Skaza, J., Murlidaran, S., Varshney, A., Wen, Z., Eckstein, M. P., & Beyeler, M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.23.660990
Self-citationDynamic neural compensation for distorted orientation perception in chronic astigmatism
Son, S., Kang, H.-G., Kim, H. R., Shim, W. M., & Lee, J. (2025) · iScience · doi:10.1016/j.isci.2025.113518
Zhao, Z., & Asakawa, T. (2025) · BioScience Trends · doi:10.5582/bst.2025.01341
Kasowski, J., Varshney, A., & Beyeler, M. (2025) · ACM Symposium on Virtual Reality Software and Technology (VRST) · doi:10.1145/3756884.3766003
Self-citation
- Authors
- Beyeler, M., Rokem, A., Boynton, G. M., & Fine, I.
- Affiliations
- University of Washington (US)
- Corresponding author
- Beyeler, Michael
- Venue
- Journal of Neural Engineering
- Publisher
- IOP Publishing
- Published
- 2017-08-22
- Volume
- 14
- Issue
- 5
- Pages
- 051003
- ISSN
- 1741-2552 (ISSN-L)
- 1741-2560
- PMC
- PMC5953572
- OpenAlex
- W2950139901
- Cited by
- 102
- References
- 230
- Citations by year
- 2026: 4 · 2025: 15 · 2024: 8 · 2023: 2 · 2022: 16 · 2021: 13 · 2020: 15 · 2019: 12 · 2018: 9 · 2017: 7 · 2015: 1
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Neural Engineering (publishedVersion)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Gordon and Betty Moore Foundation
- Washington Research Foundation (Funds for Innovation in Neuroengineering and Data-Intensive Discovery (MB))
- Alfred P Sloan Foundation
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Keywords
- retinal prosthesis, cortical plasticity, visual plasticity, perceptual learning, vision restoration, hierarchical visual processing, developmental plasticity, adult plasticity, visual learning
- MeSH terms
- Humans, Learning, Neuronal Plasticity, Visual Cortex, Visual Perception, Visual Prosthesis, Optogenetics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review