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Microglia‐specific ApoE knock‐out does not alter Alzheimer's disease plaque pathogenesis or gene expression

Henningfield, C. M., Arreola, M. A., Soni, N., Spangenberg, E. E., & Green, K. N. (2022) · Glia · doi:10.1002/glia.24105 · Cited by 40

The presence of apoE4, not the absence of apoE3, contributes to AD pathology

Teter, B., Raber, J., Nathan, B., & Crutcher, K. A. (2002) · Journal of Alzheimer's Disease · doi:10.3233/jad-2002-4305 · Cited by 37

Hippocampus-related cognitive impairments in young apoE4 targeted replacement mice

Salomon-Zimri, S., Boehm-Cagan, A., Liraz, O., & Michaelson, D. M. (2013) · Neurodegenerative Diseases · doi:10.1159/000354777 · Cited by 34

APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice

Pankiewicz, J. E., Baquero-Buitrago, J., Sanchez, S., Lopez-Contreras, J., Kim, J., Sullivan, P. M., Holtzman, D. M., & Sadowski, M. J. (2017) · Molecular Neurodegeneration · doi:10.1186/s13024-017-0156-1 · Cited by 34

Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors

Liu, L., Aboud, O., Jones, R. A., Mrak, R. E., Griffin, W. S. T., & Barger, S. W. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-175 · Cited by 33

APOE from astrocytes restores Alzheimer’s Aβ-pathology and DAM-like responses in APOE deficient microglia

Preman, P., Moechars, D., Fertan, E., Wolfs, L., Serneels, L., Shah, D., Lamote, J., Poovathingal, S., Snellinx, A., Mancuso, R., et al. (2024) · EMBO Molecular Medicine · doi:10.1038/s44321-024-00162-7 · Cited by 32

The distribution of cerebrovascular amyloid in Alzheimer’s disease varies with ApoE genotype

Trembath, D., Ervin, J. F., Broom, L., Szymanski, M., Welsh-Bohmer, K., Pieper, C., & Hulette, C. M. (2006) · Acta Neuropathologica · doi:10.1007/s00401-006-0162-9 · Cited by 31

Mitochondrial transcription factor A (TFAM) gene variation and risk of late-onset Alzheimer's disease

Alvarez, V., Corao, A. I., Alonso-Montes, C., Sánchez-Ferrero, E., De Mena, L., Morales, B., García-Castro, M., & Coto, E. (2008) · Journal of Alzheimer s Disease · doi:10.3233/jad-2008-13305 · Cited by 27

AAVrh.10 delivery of novel APOE2-Christchurch variant suppresses amyloid and Tau pathology in alzheimer's disease mice

Günaydin, C., Sondhi, D., Kaminsky, S. M., Lephart, H. C., Leopold, P. L., Hackett, N. R., Khanna, R., & Crystal, R. G. (2024) · Molecular Therapy · doi:10.1016/j.ymthe.2024.11.003 · Cited by 26

Use of Genetic Variation as Biomarkers for Alzheimer's Disease

Reitz, C., & Mayeux, R. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04945.x · Cited by 24

Do Microglia default on network maintenance in Alzheimer's disease?

Southam, K. A., Vincent, A. J., & Small, D. H. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-151075 · Cited by 20

Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains

Gamache, J., Gingerich, D., Shwab, E. K., Barrera, J., Garrett, M. E., Hume, C., Crawford, G. E., Ashley-Koch, A. E., & Chiba-Falek, O. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01120-5 · Cited by 20

Apolipoprotein E Proteinopathy Is a Major Dementia-Associated Pathologic Biomarker in Individuals with or without the APOE Epsilon 4 Allele

Gal, J., Katsumata, Y., Zhu, H., Srinivasan, S., Chen, J., Johnson, L. A., Wang, W.-X., Golden, L. R., Wilcock, D. M., Jicha, G. A., et al. (2022) · The American Journal of Pathology · doi:10.1016/j.ajpath.2021.11.013 · Cited by 17

Apolipoprotein E, Aβ‐Amyloid, and the Molecular Pathology of Alzheimer's Disease Therapeutic Implicationsa

KAPLITT, M., GOURAS, G. K., MAKIMURA, H., JOVANOVIC, J., SWEENEY, D., GREENGARD, P., RELKIN, N. R., & GANDY, S. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb32597.x · Cited by 12

No association between alpha-1-antichymotrypsin polymorphism and Alzheimer's disease in Koreans

Kim, K. W., Jhoo, J. H., Lee, K. U., Lee, D. Y., Lee, J. H., Youn, J. Y., Lee, B. J., Han, S. H., & Woo, J. I. (2000) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(20000424)91:5 · Cited by 6

No association between the alpha 1‐antichymotrypsin A allele and Alzheimer's disease

Murphy, G. M., Sullivan, E. V., Gallagher-Thompson, D. E., Thompson, L. W., van Duijn, C. M., Forno, L. S., Ellis, W. G., Jagust, W. J., Yesavage, J. A., & Tinklenberg, J. R. (1997) · Neurology · doi:10.1212/wnl.48.5.1313 · Cited by 37

Quantitation of amyloid beta-protein (A beta) in the cortex during aging and in Alzheimer's disease.

(1998) · Europe PMC (PubMed Central) · Cited by 145

Amyloid beta protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. Predominance of A beta 42(43) and association of A beta 40 with cored plaques.

Fukumoto, H., Asami-Odaka, A., Suzuki, N., Shimada, H., Ihara, Y., & Iwatsubo, T. (1996) · Europe PMC (PubMed Central) · Cited by 108

Reduction of β‐amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease

Motter, R., Vigo‐Pelfrey, C., Kholodenko, D., Barbour, R., Johnson‐Wood, K., Galasko, D., Chang, L., Miller, B., Clark, C., Green, R., et al. (1995) · Annals of Neurology · doi:10.1002/ana.410380413 · Cited by 701