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Language performance in Alzheimer's disease and mild cognitive impairment: A comparative review
Abstract
Mild cognitive impairment (MCI) manifests as memory impairment in the absence of dementia and progresses to Alzheimer's disease (AD) at a rate of around 15% per annum, versus 1-2% in the general population. It thus constitutes a primary target for investigation of early markers of AD. Language deficits occur early in AD, and performance on verbal tasks is an important diagnostic criterion for both AD and MCI. We review language performance in MCI, compare these findings to those seen in AD, and identify the primary issues in understanding language performance in MCI and selecting tasks with diagnostic and prognostic value.
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“In the field of neurodegeneration, speech and language assessments are useful for diagnosing aphasic syndromes and for characterizing other disorders.”
From Speech and language markers of neurodegeneration: a call for global equity (2023) · cites this paper as [3]
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“Some of these deficits may actually occur preclini cally in each of these disorders. 3,33-36”
From Speech and language markers of neurodegeneration: a call for global equity (2023) · cites this paper as [3]
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“Our cross-sectional findings are consistent with numerous reports that have compared fluency measures at a single testing between participants with AD and unimpaired participants(1-7) and between participants with MCI or preclinical AD and unimpaired participants.(2,9-12) In these cross-sectional analyses, we found th…”
Result
Metadata
- Authors
- Taler, V., & Phillips, N. A.
- Affiliations
- Concordia University (CA)
- Corresponding author
- Phillips, Natalie A.
- Venue
- Journal of Clinical and Experimental Neuropsychology
- Publisher
- Informa UK Limited
- Published
- 2008-06-04
- Volume
- 30
- Issue
- 5
- Pages
- 501-556
- ISSN
- 0165-0475 (ISSN-L)
- 1380-3395
- 1744-411X
- OpenAlex
- W2021720310
- Cited by
- 529
- References
- 295
- Citations by year
- 2026: 43 · 2025: 35 · 2024: 38 · 2023: 31 · 2022: 43 · 2021: 55 · 2020: 53 · 2019: 37 · 2018: 18 · 2017: 22 · 2016: 21 · 2015: 31 · 2014: 24 · 2013: 17 · 2012: 19
- FWCI
- 9.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical and Experimental Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Health Sciences › Medicine › Oncology › Cancer-related cognitive impairment studies
- Keywords
- Alzheimer's disease, mild cognitive impairment, language performance, language deficits, verbal tasks, diagnostic criteria, prognostic value, memory impairment
- MeSH terms
- Aged, Alzheimer Disease, Anomia, Cerebral Cortex, Cognition Disorders, Dementia, Diagnosis, Differential, Dominance, Cerebral, Hippocampus, Humans, Language Disorders, Language Tests, Neuropsychological Tests, Psychometrics, Mental Recall, Reference Values, Verbal Learning, Dementia, Vascular, Reproducibility of Results, Aphasia, Primary Progressive
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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