Cited by 463Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMemory and Neural MechanismsNeural and Behavioral Psychology Studies

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Neuroimaging Studies of Amygdala Function in Anxiety Disorders

RAUCH, SCOTT L., SHIN, LISA M., WRIGHT, CHRISTOPHER I.·2003·Annals of the New York Academy of Sciences

DOI 10.1111/j.1749-6632.2003.tb07096.x

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Abstract

A bstract : Neuroimaging research has helped to advance neurobiological models of anxiety disorders. The amygdala is known to play an important role in normal fear conditioning and is implicated in the pathophysiology of anxiety disorders. The amygdala may also be a target for the beneficial effects of cognitive‐behavioral and medication treatments for anxiety disorders. In the current paper, we review neuroimaging research pertaining to the role of the amygdala in anxiety disorders and their treatment. Moreover, we discuss the development of new neuroimaging paradigms for measuring aspects of amygdala function, as well as the function of related brain regions. We conclude that such tools hold great promise for facilitating progress in relevant basic neuroscience as well as clinical research domains.

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Authors: RAUCH, S. L., SHIN, L. M., & WRIGHT, C. I.
Affiliations: Harvard University (US)
Tufts University (US)
Brigham and Women's Hospital (US)
Corresponding author: RAUCH, SCOTT L.
ORCID: RAUCH, SCOTT L.
SHIN, LISA M.
WRIGHT, CHRISTOPHER I.
Venue: Annals of the New York Academy of Sciences
Publisher: Wiley
Published: 2003-04
Volume: 985
Issue: 1
Pages: 389-410
ISSN: 0077-8923 (ISSN-L)
1749-6632
DOI: 10.1111/j.1749-6632.2003.tb07096.x
OpenAlex: W2008245053
Cited by: 463
References: 110
Citations by year: 2026: 7 · 2025: 12 · 2024: 12 · 2023: 21 · 2022: 9 · 2021: 23 · 2020: 15 · 2019: 17 · 2018: 18 · 2017: 14 · 2016: 9 · 2015: 16 · 2014: 19 · 2013: 30 · 2012: 27
FWCI: 4.68
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 1029 d)
Locations: Annals of the New York Academy of Sciences (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords: amygdala, anxiety disorders, fear conditioning, cognitive behavioral therapy, pharmacotherapy, treatment response
MeSH terms: Amygdala, Anxiety Disorders, Brain Mapping, Humans, Magnetic Resonance Imaging, Obsessive-Compulsive Disorder, Phobic Disorders, Tomography, Emission-Computed, Panic Disorder

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Neuroimaging Studies of Amygdala Function in Anxiety Disorders

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