The DOI matches its Crossref record; 360 of the 360 references it cites were found in a registry or an index.
Molecular Mechanisms and Therapeutical Implications of Intramembrane Receptor/Receptor Interactions among Heptahelical Receptors with Examples from the Striatopallidal GABA Neurons
Open accessAbstract
The molecular basis for the known intramembrane receptor/receptor interactions among G protein-coupled receptors was postulated to be heteromerization based on receptor subtype-specific interactions between different types of receptor homomers. The discovery of GABAB heterodimers started this field rapidly followed by the discovery of heteromerization among isoreceptors of several G protein-coupled receptors such as δ/κ opioid receptors. Heteromerization was also discovered among distinct types of G protein-coupled receptors with the initial demonstration of somatostatin SSTR5/dopamine D2 and adenosine A1/dopamine D1 heteromeric receptor complexes. The functional meaning of these heteromeric complexes is to achieve direct or indirect (via adapter proteins) intramembrane receptor/receptor interactions in the complex. G protein-coupled receptors also form heteromeric complexes involving direct interactions with ion channel receptors, the best example being the GABAA/dopamine D5 receptor heteromerization, as well as with receptor tyrosine kinases and with receptor activity modulating proteins. As an example, adenosine, dopamine, and glutamate metabotropic receptor/receptor interactions in the striatopallidal GABA neurons are discussed as well as their relevance for Parkinson's disease, schizophrenia, and drug dependence. The heterodimer is only one type of heteromeric complex, and the evidence is equally compatible with the existence of higher order heteromeric complexes, where also adapter proteins such as homer proteins and scaffolding proteins can exist. These complexes may assist in the process of linking G protein-coupled receptors and ion channel receptors together in a receptor mosaic that may have special integrative value and may constitute the molecular basis for some forms of learning and memory.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Dual Signaling Regulated by Calcyon, a D1 Dopamine Receptor Interacting Protein
Lezcano, N., Mrzljak, L., Eubanks, S., Levenson, R., Goldman-Rakic, P., & Bergson, C. (2000) · Science · doi:10.1126/science.287.5458.1660 · Cited by 175
RetractedHebb, D. O. (2005) · doi:10.4324/9781410612403 · Cited by 9,825
Cell Signaling by Receptor Tyrosine Kinases
Lemmon, M. A., & Schlessinger, J. (2010) · Cell · doi:10.1016/j.cell.2010.06.011 · Cited by 7,929
International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels
Catterall, W. A., Chandy, K. G., Clapham, D. E., Gutman, G. A., Hofmann, F., Harmar, A. J., Abernethy, D. R., & Spedding, M. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.4.5 · Cited by 7,126
The Organization of Behavior; A Neuropsychological Theory.
Attneave, F., B., M., & Hebb, D. O. (1950) · The American Journal of Psychology · doi:10.2307/1418888 · Cited by 5,146
Functional architecture of basal ganglia circuits: neural substrates of parallel processing
Alexander, G. E., & Crutcher, M. D. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90107-l · Cited by 4,131
Cell Signaling by Receptor Tyrosine Kinases
Schlessinger, J. (2000) · Cell · doi:10.1016/s0092-8674(00)00114-8 · Cited by 3,774
Paxinos, G. (1985) · Cited by 3,715
Dopamine receptors: from structure to function
MISSALE, C., NASH, S. R., ROBINSON, S. W., JABER, M., & CARON, M. G. (1998) · Physiological Reviews · doi:10.1152/physrev.1998.78.1.189 · Cited by 3,633
The Energy Landscapes and Motions of Proteins
Frauenfelder, H., Sligar, S. G., & Wolynes, P. G. (1991) · Science · doi:10.1126/science.1749933 · Cited by 3,250
Transcriptional regulation by the phosphorylation-dependent factor CREB
Mayr, B., & Montminy, M. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35085068 · Cited by 2,587
Hunter, T. (2000) · Cell · doi:10.1016/s0092-8674(00)81688-8 · Cited by 2,586
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
Fredholm, B. B., IJzerman, A. P., Jacobson, K. A., Klotz, K.-N., & Linden, J. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01511-4 · Cited by 2,585
Protein modules and signalling networks
Pawson, T. (1995) · Nature · doi:10.1038/373573a0 · Cited by 2,420
The metabotropic glutamate receptors: Structure and functions
Pin, J.-P., & Duvoisin, R. (1995) · Neuropharmacology · doi:10.1016/0028-3908(94)00129-g · Cited by 2,266
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
Pawson, T., & Scott, J. D. (1997) · Science · doi:10.1126/science.278.5346.2075 · Cited by 2,256
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
McLatchie, L. M., Fraser, N. J., Main, M. J., Wise, A., Brown, J., Thompson, N., Solari, R., Lee, M. G., & Foord, S. M. (1998) · Nature · doi:10.1038/30666 · Cited by 2,134
Ungerstedt, U. (1971) · Acta Physiologica Scandinavica · doi:10.1111/j.1365-201x.1971.tb11000.x · Cited by 1,922
Dimerization of cell surface receptors in signal transduction
Heldin, C.-H. (1995) · Cell · doi:10.1016/0092-8674(95)90404-2 · Cited by 1,634
Modulation of memory fields by dopamine Dl receptors in prefrontal cortex
Williams, G. V., & Goldman-Rakic, P. S. (1995) · Nature · doi:10.1038/376572a0 · Cited by 1,593
Nomenclature and classification of purinoceptors.
Fredholm, B. B., Abbracchio, M. P., Burnstock, G., Daly, J. W., Harden, T. K., Jacobson, K. A., Leff, P., & Williams, M. (1994) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06782-1 · Cited by 1,585
Molecular tinkering of G protein-coupled receptors: an evolutionary success
Bockaert, J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.7.1723 · Cited by 1,550
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
Luttrell, L. M., Ferguson, S. S. G., Daaka, Y., Miller, W. E., Maudsley, S., Della Rocca, G. J., Lin, F.-T., Kawakatsu, H., Owada, K., Luttrell, D. K., et al. (1999) · Science · doi:10.1126/science.283.5402.655 · Cited by 1,475
Herdegen, T., & Leah, J. D. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00018-6 · Cited by 1,350
Jentsch, J. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00060-8 · Cited by 1,314
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors
Gether, U. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0390 · Cited by 1,263
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor
Kunishima, N., Shimada, Y., Tsuji, Y., Sato, T., Yamamoto, M., Kumasaka, T., Nakanishi, S., Jingami, H., & Morikawa, K. (2000) · Nature · doi:10.1038/35039564 · Cited by 1,249
GABAB-receptor subtypes assemble into functional heteromeric complexes
Kaupmann, K., Malitschek, B., Schuler, V., Heid, J., Froestl, W., Beck, P., Mosbacher, J., Bischoff, S., Kulik, A., Shigemoto, R., et al. (1998) · Nature · doi:10.1038/25360 · Cited by 1,195
Heterodimerization is required for the formation of a functional GABAB receptor
White, J. H., Wise, A., Main, M. J., Green, A., Fraser, N. J., Disney, G. H., Barnes, A. A., Emson, P., Foord, S. M., & Marshall, F. H. (1998) · Nature · doi:10.1038/25354 · Cited by 1,182
Addiction, Dopamine, and the Molecular Mechanisms of Memory
Berke, J. D., & Hyman, S. E. (2000) · Neuron · doi:10.1016/s0896-6273(00)81056-9 · Cited by 1,181
G-protein-coupled receptor heterodimerization modulates receptor function
Jordan, B. A., & Devi, L. A. (1999) · Nature · doi:10.1038/21441 · Cited by 1,166
Migaud, M., Charlesworth, P., Dempster, M., Webster, L. C., Watabe, A. M., Makhinson, M., He, Y., Ramsay, M. F., Morris, R. G. M., Morrison, J. H., et al. (1998) · Nature · doi:10.1038/24790 · Cited by 1,160
Sweatt, J. D. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00054.x · Cited by 1,131
Carlsson, M., & Carlsson, A. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90108-m · Cited by 1,082
GABAB receptors function as a heteromeric assembly of the subunits GABABR1 and GABABR2
Jones, K. A., Borowsky, B., Tamm, J. A., Craig, D. A., Durkin, M. M., Dai, M., Yao, W.-J., Johnson, M., Gunwaldsen, C., Huang, L.-Y., et al. (1998) · Nature · doi:10.1038/25348 · Cited by 1,079
Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins
Tu, J. C., Xiao, B., Naisbitt, S., Yuan, J. P., Petralia, R. S., Brakeman, P., Doan, A., Aakalu, V. K., Lanahan, A. A., Sheng, M., et al. (1999) · Neuron · doi:10.1016/s0896-6273(00)80810-7 · Cited by 1,050
G-protein-coupled receptors and signaling networks: emerging paradigms
Marinissen, M. J., & Gutkind, J. S. (2001) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(00)01678-3 · Cited by 1,049
Naisbitt, S., Kim, E., Tu, J. C., Xiao, B., Sala, C., Valtschanoff, J., Weinberg, R. J., Worley, P. F., & Sheng, M. (1999) · Neuron · doi:10.1016/s0896-6273(00)80809-0 · Cited by 1,009
Alexander, G. E. (1998) · Cited by 890
Rocheville, M., Lange, D. C., Kumar, U., Patel, S. C., Patel, R. C., & Patel, Y. C. (2000) · Science · doi:10.1126/science.288.5463.154 · Cited by 888
Tu, J. C., Xiao, B., Yuan, J. P., Lanahan, A. A., Leoffert, K., Li, M., Linden, D. J., & Worley, P. F. (1998) · Neuron · doi:10.1016/s0896-6273(00)80589-9 · Cited by 862
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
Luttrell, L. M., Roudabush, F. L., Choy, E. W., Miller, W. E., Field, M. E., Pierce, K. L., & Lefkowitz, R. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.041604898 · Cited by 831
Adenosine–dopamine receptor–receptor interactions as an integrative mechanism in the basal ganglia
Ferré, S., Fuxe, K., B. Fredholm, B., Morelli, M., & Popoli, P. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01096-5 · Cited by 824
Self-citationAdenosine in the central nervous system: release mechanisms and extracellular concentrations
Latini, S., & Pedata, F. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00607.x · Cited by 777
Hebert, T. E., Moffett, S., Morello, J.-P., Loisel, T. P., Bichet, D. G., Barret, C., & Bouvier, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.27.16384 · Cited by 775
Greengard, P., Allen, P. B., & Nairn, A. C. (1999) · Neuron · doi:10.1016/s0896-6273(00)80798-9 · Cited by 746
Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET
Okubo, Y., Suhara, T., Suzuki, K., Kobayashi, K., Inoue, O., Terasaki, O., Someya, Y., Sassa, T., Sudo, Y., Matsushima, E., et al. (1997) · Nature · doi:10.1038/385634a0 · Cited by 710
A Trafficking Checkpoint Controls GABAB Receptor Heterodimerization
Margeta-Mitrovic, M., Jan, Y. N., & Jan, L. Y. (2000) · Neuron · doi:10.1016/s0896-6273(00)00012-x · Cited by 680
Hughes, P., & Dragunow, M. (1995) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06819-x · Cited by 678
Small Peptides as Potent Mimetics of the Protein Hormone Erythropoietin
Wrighton, N. C., Farrell, F. X., Chang, R., Kashyap, A. K., Barbone, F. P., Mulcahy, L. S., Johnson, D. L., Barrett, R. W., Jolliffe, L. K., & Dower, W. J. (1996) · Science · doi:10.1126/science.273.5274.458 · Cited by 672
Oligomerization of G-protein-coupled transmitter receptors
Bouvier, M. (2001) · Nature Reviews Neuroscience · doi:10.1038/35067575 · Cited by 669
Functional and Anatomical Aspects of Prefrontal Pathology in Schizophrenia
Goldman-Rakic, P. S., & Selemon, L. D. (1997) · Schizophrenia Bulletin · doi:10.1093/schbul/23.3.437 · Cited by 668
Fink, J. S., Weaver, D. R., Rivkees, S. A., Peterfreund, R. A., Pollack, A. E., Adler, E. M., & Reppert, S. M. (1992) · Molecular Brain Research · doi:10.1016/0169-328x(92)90173-9 · Cited by 650
Angers, S., Salahpour, A., Joly, E., Hilairet, S., Chelsky, D., Dennis, M., & Bouvier, M. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.7.3684 · Cited by 638
Impey, S., Obrietan, K., & Storm, D. R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80747-3 · Cited by 613
Complexity in Biological Signaling Systems
Weng, G., Bhalla, U. S., & Iyengar, R. (1999) · Science · doi:10.1126/science.284.5411.92 · Cited by 609
Adenosine, Adenosine Receptors and the Actions of Caffeine
Fredholm, B. B. (1995) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1995.tb00111.x · Cited by 597
The Shank family of scaffold proteins
Sheng, M., & Kim, E. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.11.1851 · Cited by 578
Le Moine, C., & Bloch, B. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903550308 · Cited by 575
Role of Heteromer Formation in GABA B Receptor Function
Kuner, R., Köhr, G., Grünewald, S., Eisenhardt, G., Bach, A., & Kornau, H.-C. (1999) · Science · doi:10.1126/science.283.5398.74 · Cited by 562
The pathway to signal achievement
Egan, S. E., & Weinberg, R. A. (1993) · Nature · doi:10.1038/365781a0 · Cited by 559
PAR3 is a cofactor for PAR4 activation by thrombin
Nakanishi-Matsui, M., Zheng, Y.-W., Sulciner, D. J., Weiss, E. J., Ludeman, M. J., & Coughlin, S. R. (2000) · Nature · doi:10.1038/35007085 · Cited by 557
Oligomerization of μ- and δ-Opioid Receptors
George, S. R., Fan, T., Xie, Z., Tse, R., Tam, V., Varghese, G., & O'Dowd, B. F. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m000345200 · Cited by 556
Ferre, S., von Euler, G., Johansson, B., Fredholm, B. B., & Fuxe, K. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7238 · Cited by 552
Self-citationYung, K. K. L., Bolam, J. P., Smith, A. D., Hersch, S. M., Ciliax, B. J., & Levey, A. I. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00536-e · Cited by 542
Metabotropic Glutamate Receptor 5 Is a Disulfide-linked Dimer
Romano, C., Yang, W.-L., & O'Malley, K. L. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.45.28612 · Cited by 536
Schiffmann, S. N., Jacobs, O., & Vanderhaeghen, J. (1991) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1991.tb08257.x · Cited by 530
Subtypes of the Somatostatin Receptor Assemble as Functional Homo- and Heterodimers
Rocheville, M., Lange, D. C., Kumar, U., Sasi, R., Patel, R. C., & Patel, Y. C. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.11.7862 · Cited by 527
Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain
Shigemoto, R., Nomura, S., Ohishi, H., Sugihara, H., Nakanishi, S., & Mizuno, N. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90227-c · Cited by 520
Distribution, biochemistry and function of striatal adenosine A2A receptors
Svenningsson, P. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00011-8 · Cited by 516
Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat
Testa, C., Standaert, D., Young, A., & Penney, J. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-05-03005.1994 · Cited by 510
Johansson, B., Halldner, L., Dunwiddie, T. V., Masino, S. A., Poelchen, W., Giménez-Llort, L., Escorihuela, R. M., Fernández-Teruel, A., Wiesenfeld-Hallin, Z., Xu, X.-J., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.161292398 · Cited by 505
AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration
AbdAlla, S., Lother, H., & Quitterer, U. (2000) · Nature · doi:10.1038/35024095 · Cited by 503
Hillion, J., Canals, M., Torvinen, M., Casadó, V., Scott, R., Terasmaa, A., Hansson, A., Watson, S., Olah, M. E., Mallol, J., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107731200 · Cited by 500
Self-citationIncreased AT1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness
AbdAlla, S., Lother, H., el Massiery, A., & Quitterer, U. (2001) · Nature Medicine · doi:10.1038/nm0901-1003 · Cited by 496
Opioids: first lessons from knockout mice
Kieffer, B. L. (1999) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(98)01279-6 · Cited by 489
Bergson, C., Mrzljak, L., Smiley, J., Pappy, M., Levenson, R., & Goldman-Rakic, P. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-12-07821.1995 · Cited by 488
Christopoulos, G., Perry, K. J., Morfis, M., Tilakaratne, N., Gao, Y., Fraser, N. J., Main, M. J., Foord, S. M., & Sexton, P. M. (1999) · Molecular Pharmacology · doi:10.1124/mol.56.1.235 · Cited by 486
Wu, G.-Y., Deisseroth, K., & Tsien, R. W. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051634198 · Cited by 477
Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors
Pierce, K. L., & Lefkowitz, R. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35094577 · Cited by 476
Robertson, G. S., & Fibiger, H. C. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90054-6 · Cited by 474
Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices.
Lemmon, M. A., Flanagan, J. M., Hunt, J. F., Adair, B. D., Bormann, B. J., Dempsey, C. E., & Engelman, D. M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42569-0 · Cited by 468
Snyder, S. H. (1985) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.08.030185.000535 · Cited by 467
Proteomics: new perspectives, new biomedical opportunities
Banks, R. E., Dunn, M. J., Hochstrasser, D. F., Sanchez, J.-C., Blackstock, W., Pappin, D. J., & Selby, P. J. (2000) · The Lancet · doi:10.1016/s0140-6736(00)03214-1 · Cited by 451
Dopamine D 1 and adenosine A 1 receptors form functionally interacting heteromeric complexes
Ginés, S., Hillion, J., Torvinen, M., Le Crom, S., Casadó, V., Canela, E. I., Rondin, S., Lew, J. Y., Watson, S., Zoli, M., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.150241097 · Cited by 445
Self-citationON THE COOPERATIVITY OF BIOLOGICAL MEMBRANES
Changeux, J.-P., Thiéry, J., Tung, Y., & Kittel, C. (1967) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.57.2.335 · Cited by 434
Liu, F., Wan, Q., Pristupa, Z. B., Yu, X.-M., Wang, Y. T., & Niznik, H. B. (2000) · Nature · doi:10.1038/35002014 · Cited by 431
Gurevich, E. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00066-9 · Cited by 431
SH2 domains, interaction modules and cellular wiring
Pawson, T., Gish, G. D., & Nash, P. (2001) · Trends in Cell Biology · doi:10.1016/s0962-8924(01)02154-7 · Cited by 408
Maudsley, S., Pierce, K. L., Zamah, A. M., Miller, W. E., Ahn, S., Daaka, Y., Lefkowitz, R. J., & Luttrell, L. M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.13.9572 · Cited by 407
Homer: a link between neural activity and glutamate receptor function
Xiao, B., Cheng Tu, J., & Worley, P. F. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00087-8 · Cited by 406
Hermans, E., & Challiss, R. A. J. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3590465 · Cited by 404
Signal transduction by allosteric receptor oligomerization
Schlessinger, J. (1988) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(88)90219-8 · Cited by 399
Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system
Rosin, D. L., Robeva, A., Woodard, R. L., Guyenet, P. G., & Linden, J. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19981116)401:2<163::aid-cne2>3.0.co;2-d · Cited by 389
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
Kohout, T. A., Lin, F.-T., Perry, S. J., Conner, D. A., & Lefkowitz, R. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1601 · Cited by 367
Ferré, S., Karcz-Kubicha, M., Hope, B. T., Popoli, P., Burgueño, J., Gutiérrez, M. A., Casadó, V., Fuxe, K., Goldberg, S. R., Lluis, C., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172393799 · Cited by 365
Self-citationAdenosine-dopamine interactions in the brain
Ferré, S., Fuxe, K., von Euler, G., Johansson, B., & Fredholm, B. B. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90291-9 · Cited by 364
Self-citationKanda, T., Jackson, M. J., Smith, L. A., Pearce, R. K. B., Nakamura, J., Kase, H., Kuwana, Y., & Jenner, P. (1998) · Annals of Neurology · doi:10.1002/ana.410430415 · Cited by 354
GABAB receptors – the first 7TM heterodimers
Marshall, F. H., Jones, K. A., Kaupmann, K., & Bettler, B. (1999) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(99)01383-8 · Cited by 345
Jordan, B. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.011384898 · Cited by 328
Rewarding Actions of Phencyclidine and Related Drugs in Nucleus Accumbens Shell and Frontal Cortex
Carlezon, & Wise, R. A. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-09-03112.1996 · Cited by 327
GABA-mediated biphasic inhibitory responses in hippocampus
Alger, B. E., & Nicoll, R. A. (1979) · Nature · doi:10.1038/281315a0 · Cited by 326
Vanhoutte, P., Barnier, J.-V., Guibert, B., Pagès, C., Besson, M.-J., Hipskind, R. A., & Caboche, J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.136 · Cited by 323
Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking
Miller, W. E., & Lefkowitz, R. J. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00190-3 · Cited by 322
The Role of the Striatopallidal and Extended Amygdala Systems in Drug Addiction
KOOB, G. F. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09282.x · Cited by 321
G-protein-coupled receptors function as oligomers in vivo
Overton, M. C., & Blumer, K. J. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00386-9 · Cited by 317
Nguyen, J. T., Turck, C. W., Cohen, F. E., Zuckermann, R. N., & Lim, W. A. (1998) · Science · doi:10.1126/science.282.5396.2088 · Cited by 314
Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone
Yamauchi, T., Ueki, K., Tobe, K., Tamemoto, H., Sekine, N., Wada, M., Honjo, M., Takahashi, M., Takahashi, T., Hirai, H., et al. (1997) · Nature · doi:10.1038/36369 · Cited by 285
Fuxe, K., Ferré, S., Zoli, M., & Agnati, L. F. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00049-0 · Cited by 280
Self-citationHeightened sensitivity of a lattice of membrane receptors
Duke, T. A. J., & Bray, D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.10104 · Cited by 276
Dopamine D2 Receptor Dimers and Receptor-Blocking Peptides
Ng, G. Y. K., O'Dowd, B. F., Lee, S. P., Chung, H. T., Brann, M. R., Seeman, P., & George, S. R. (1996) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1996.1489 · Cited by 273
Positive and negative regulatory mechanisms that mediate long-term memory storage
Abel, T., & Kandel, E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00050-7 · Cited by 267
Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease
Richardson, P. J., Kase, H., & Jenner, P. G. (1997) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(97)01096-1 · Cited by 263
Cell surface adenosine deaminase: Much more than an ectoenzyme
Franco, R., Casadó, V., Ciruela, F., Saura, C., Mallol, J., Canela, E. I., & Lluis, C. (1997) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00013-0 · Cited by 257
Self-citationMcVey, M., Ramsay, D., Kellett, E., Rees, S., Wilson, S., Pope, A. J., & Milligan, G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008902200 · Cited by 257
Mrzljak, L., Levey, A. I., & Goldman-Rakic, P. S. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.11.5194 · Cited by 256
Chen, J.-F., Moratalla, R., Impagnatiello, F., Grandy, D. K., Cuellar, B., Rubinstein, M., Beilstein, M. A., Hackett, E., Fink, J. S., Low, M. J., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1970 · Cited by 256
Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons
Schiffmann, S., & Vanderhaeghen, J. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-03-01080.1993 · Cited by 251
The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain
Ferre, S., O'Connor, W., Fuxe, K., & Ungerstedt, U. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-12-05402.1993 · Cited by 251
Self-citationStriatal dopamine- and glutamate-mediated dysregulation in experimental parkinsonism
Chase, T. N., & Oh, J. D. (2000) · Trends in Neurosciences · doi:10.1016/s1471-1931(00)00018-5 · Cited by 251
Gerfen, C. R., & Wilson, C. J. (1996) · Handbook of Chemical Neuroanatomy · doi:10.1016/s0924-8196(96)80004-2 · Cited by 250
Antiparkinsonian effect of a new selective adenosine A2Areceptor antagonist in MPTP-treated monkeys
Grondin, R., Bédard, P. J., Tahar, A. H., Grégoire, L., Mori, A., & Kase, H. (1999) · Neurology · doi:10.1212/wnl.52.8.1673 · Cited by 249
Adenosine-dopamine interactions in the ventral striatum
Ferré, S. (1997) · Psychopharmacology · doi:10.1007/s002130050380 · Cited by 248
Self-citationKanda, T., Jackson, M. J., Smith, L. A., Pearce, R. K. B., Nakamura, J., Kase, H., Kuwana, Y., & Jenner, P. (2000) · Experimental Neurology · doi:10.1006/exnr.2000.7350 · Cited by 248
Deutch, A. Y., Lee, M. C., & Iadarola, M. J. (1992) · Molecular and Cellular Neuroscience · doi:10.1016/1044-7431(92)90030-6 · Cited by 240
Amplification of dopaminergic signaling by a positive feedback loop
Nishi, A., Bibb, J. A., Snyder, G. L., Higashi, H., Nairn, A. C., & Greengard, P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.220410397 · Cited by 238
The superfamily of heptahelical receptors
Lefkowitz, R. J. (2000) · Nature Cell Biology · doi:10.1038/35017152 · Cited by 232
Heteromeric association creates a P2Y-like adenosine receptor
Yoshioka, K., Saitoh, O., & Nakata, H. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121587098 · Cited by 231
Fraser, I. D. C., Cong, M., Kim, J., Rollins, E. N., Daaka, Y., Lefkowitz, R. J., & Scott, J. D. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00419-x · Cited by 229
Antagonists of protein–protein interactions
Cochran, A. G. (2000) · Chemistry & Biology · doi:10.1016/s1074-5521(00)00106-x · Cited by 228
Le Moine, C., & Bloch, B. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00029-2 · Cited by 225
A-kinase anchoring proteins: protein kinase A and beyond
Edwards, A. S., & Scott, J. D. (2000) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)00085-x · Cited by 224
Yan, Z., Feng, J., Fienberg, A. A., & Greengard, P. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11607 · Cited by 224
Shiozaki, S., Ichikawa, S., Nakamura, J., Kitamura, S., Yamada, K., & Kuwana, Y. (1999) · Psychopharmacology · doi:10.1007/s002130051146 · Cited by 216
Monnot, C., Bihoreau, C., Conchon, S., Curnow, K. M., Corvol, P., & Clauser, E. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.3.1507 · Cited by 215
D2/D3 Dopamine Receptor Heterodimers Exhibit Unique Functional Properties
Scarselli, M., Novi, F., Schallmach, E., Lin, R., Baragli, A., Colzi, A., Griffon, N., Corsini, G. U., Sokoloff, P., Levenson, R., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102297200 · Cited by 214
Tallaksen-Greene, S. J., Kaatz, K. W., Romano, C., & Albin, R. L. (1998) · Brain Research · doi:10.1016/s0006-8993(97)01141-4 · Cited by 214
Identification of a GABAB Receptor Subunit, gb2, Required for Functional GABAB Receptor Activity
Ng, G. Y. K., Clark, J., Coulombe, N., Ethier, N., Hebert, T. E., Sullivan, R., Kargman, S., Chateauneuf, A., Tsukamoto, N., McDonald, T., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.12.7607 · Cited by 212
β-Adrenergic receptors: Evidence for negative cooperativity
Limbird, L. E., Meyts, P. D., & Lefkowitz, R. J. (1975) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(75)90815-3 · Cited by 209
Lundberg, J. M., Hedlund, B., & Bartfai, T. (1982) · Nature · doi:10.1038/295147a0 · Cited by 201
Specificity and promiscuity in membrane helix interactions
Lemmon, M. A., & Engelman, D. M. (1994) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583500004522 · Cited by 200
Svenningsson, P., Lindskog, M., Ledent, C., Parmentier, M., Greengard, P., Fredholm, B. B., & Fisone, G. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.4.1856 · Cited by 196
Hold 'em and Fold 'em: Chaperones and Signal Transduction
Bohen, S. P., Kralli, A., & Yamamoto, K. R. (1995) · Science · doi:10.1126/science.7761850 · Cited by 196
Adenosine A2AReceptors are Colocalized with and Activate Golfin Rat Striatum
Kull, B., Svenningsson, P., & Fredholm, B. B. (2000) · Molecular Pharmacology · doi:10.1124/mol.58.4.771 · Cited by 196
Svenningsson, P., Le Moine, C., Kull, B., Sunahara, R., Bloch, B., & Fredholm, B. B. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00180-2 · Cited by 193
Link between D1 and D2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain.
Seeman, P., Niznik, H. B., Guan, H. C., Booth, G., & Ulpian, C. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.24.10156 · Cited by 191
Kroeger, K. M., Hanyaloglu, A. C., Seeber, R. M., Miles, L. E. C., & Eidne, K. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011311200 · Cited by 190
Schulte, G., & Fredholm, B. B. (2000) · PubMed · Cited by 188
State-dependent cross-inhibition between transmitter-gated cation channels
Khakh, B. S., Zhou, X., Sydes, J., Galligan, J. J., & Lester, H. A. (2000) · Nature · doi:10.1038/35019066 · Cited by 188
Breysse, N., Baunez, C., Spooren, W., Gasparini, F., & Amalric, M. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-13-05669.2002 · Cited by 181
Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons
Testa, C. M., Standaert, D. G., Landwehrmeyer, G. B., Penney, J. B., & Young, A. B. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903540207 · Cited by 181
Aoyama, S., Kase, H., & Borrelli, E. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-15-05848.2000 · Cited by 180
Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor
Ng, G. Y. K., Mouillac, B., George, S. R., Caron, M., Dennis, M., Bouvier, M., & O'Dowd, B. F. (1994) · European Journal of Pharmacology: Molecular Pharmacology · doi:10.1016/0922-4106(94)90219-4 · Cited by 180
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine
Lindskog, M., Svenningsson, P., Pozzi, L., Kim, Y., Fienberg, A. A., Bibb, J. A., Fredholm, B. B., Nairn, A. C., Greengard, P., & Fisone, G. (2002) · Nature · doi:10.1038/nature00817 · Cited by 180
Ciruela, F., Escriche, M., Burgueño, J., Angulo, E., Casadó, V., Soloviev, M. M., Canela, E. I., Mallol, J., Chan, W.-Y., Lluis, C., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006960200 · Cited by 180
Self-citationAgonist-receptor efficacy I: mechanisms of efficacy and receptor promiscuity
Kenakin, T. (1995) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(00)89020-3 · Cited by 176
Conversion of a gonadotropin-releasing hormone antagonist to an agonist
Conn, P. M., Rogers, D. C., Stewart, J. M., Niedel, J., & Sheffield, T. (1982) · Nature · doi:10.1038/296653a0 · Cited by 174
Opioids and Their Complicated Receptor Complexes
Jordan, B. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00143-3 · Cited by 174
Merchant, K. M., & Dorsa, D. M. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.8.3447 · Cited by 174
Purinoceptors in the Nervous System*
Fredholm, B. B. (1995) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1995.tb00135.x · Cited by 173
Robertson, G. S., & Jian, M. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00426-6 · Cited by 172
Ferré, S., O'Connor, W. T., Snaprud, P., Ungerstedt, U., & Fuxe, K. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90521-5 · Cited by 171
Self-citationEvidence for Adenosine/Dopamine Receptor Interactions Indications for Heteromerization
Franco, R. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00144-5 · Cited by 171
Self-citationEnzymatic and extraenzymatic role of ecto‐adenosine deaminase in lymphocytes
Franco, R., Valenzuela, A., Lluis, C., & Blanco, J. (1998) · Immunological Reviews · doi:10.1111/j.1600-065x.1998.tb01569.x · Cited by 170
Self-citationFuxé, K., & Ungerstedt, U. (1974) · PubMed · Cited by 170
Ciruela, F., Saura, C., Canela, E. I., Mallol, J., Lluis, C., & Franco, R. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00023-3 · Cited by 168
Self-citationExpression of Dopamine D3 Receptor Dimers and Tetramers in Brain and in Transfected Cells
Nimchinsky, E. A., Hof, P. R., Janssen, W. G. M., Morrison, J. H., & Schmauss, C. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.46.29229 · Cited by 168
AGNATI, L. F., FUXE, K., BENFENATI, F., BATTISTINI, N., HÄRFSTRAND, A., TATEMOTO, K., HÖKFELT, T., & MUTT, V. (1983) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1983.tb07273.x · Cited by 168
Self-citationOstrom, R. S., Post, S. R., & Insel, P. A. (2000) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)39086-x · Cited by 163
Activation of Group I mGluRs Is Necessary for Induction of Long-Term Depression at Striatal Synapses
Sung, K.-W., Choi, S., & Lovinger, D. M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.5.2405 · Cited by 162
Schulte, G., & Fredholm, B. B. (2000) · Molecular Pharmacology · doi:10.1124/mol.58.3.477 · Cited by 162
Activation of the extracellular signal‐regulated kinase 2 by metabotropic glutamate receptors
Ferraguti, F., Baldani-Guerra, B., Corsi, M., Nakanishi, S., & Corti, C. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00626.x · Cited by 161
FUXE, K., AGNATI, L. F., BENFENATI, F., CIMMINO, M., ALGERI, S., HÖKFELT, T., & MUTT, V. (1981) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1981.tb06942.x · Cited by 158
Self-citationNusser, Z., Roberts, J. D. B., Baude, A., Richards, J. G., Sieghart, W., & Somogyi, P. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb00667.x · Cited by 156
Greengard, P., Nairn, A. C., Girault, J., Ouimet, C. C., Snyder, G. L., Fisone, G., Allen, P. B., Fienberg, A. A., & Nishi, A. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00057-x · Cited by 153
Fenu, S., Pinna, A., Ongini, E., & Morelli, M. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(96)00944-2 · Cited by 153
Fuxé, K., & Agnati, L. F. (1985) · Medicinal Research Reviews · doi:10.1002/med.2610050404 · Cited by 153
Self-citationFuxé, K., Agnati, L. F., Benfenati, F., Celani, M. F., Zini, I., Zoli, M., & Mutt, V. (1983) · PubMed · Cited by 153
Self-citationAdenosine A2A Agonists: A Potential New Type of Atypical Antipsychotic
Rimondini, R., Ferré, S., Ogren, S. O., & Fuxe, K. (1997) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00033-x · Cited by 152
Self-citationNg, G., George, S. R., Zastawny, R. L., Caron, M., Bouvier, M., Dennis, M., & O’Dowd, B. F. (1993) · Biochemistry · doi:10.1021/bi00094a032 · Cited by 149
GABAB receptors: drugs meet clones
Bettler, B., Kaupmann, K., & Bowery, N. G. (1998) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(98)80059-7 · Cited by 149
Ferré, S., O'Connor, W. T., Svenningsson, P., Björklund, L., Lindberg, J., Tinner, B., Strömberg, I., Goldstein, M., Ögren, S. O., Ungerstedt, U., et al. (1996) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1996.tb01617.x · Cited by 146
Self-citationKF17837: A novel selective adenosine A2A receptor antagonist with anticataleptic activity
Kanda, T., Shiozaki, S., Shimada, J., Suzuki, F., & Nakamura, J. (1994) · European Journal of Pharmacology · doi:10.1016/0014-2999(94)90551-7 · Cited by 145
Ng, G., Bertrand, S. S., Sullivan, R. J., Éthier, N., Wang, J. P., Yergey, J. A., Belley, M. L., Trimble, L. A., Bateman, K. P., Alder, L., et al. (2001) · Molecular Pharmacology · doi:10.1124/mol.59.1.144 · Cited by 142
Mori, A., Shindou, T., Ichimura, M., Nonaka, H., & Kase, H. (1996) · Advances in behavioral biology · doi:10.1007/978-1-4899-0194-1_13 · Cited by 142
Somatostatin and thyrotropin releasing hormone: Central effect on sleep and motor system
Havlicek, V., Rezek, M., & Friesen, H. G. (1976) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(76)90063-0 · Cited by 140
Mori, A., Shindou, T., Ichimura, M., Nonaka, H., & Kase, H. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00605.1996 · Cited by 140
Hormone-dependent Transactivation by the Human Androgen Receptor Is Regulated by a dnaJ Protein
Caplan, A. J., Langley, E., Wilson, E. M., & Vidal, J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.10.5251 · Cited by 139
Postsynaptic antagonistic interaction between adenosine A1, and dopamine D1 receptors
Ferré, S., Popoli, P., Giménez‐Llort, L., Finnman, U.-B., Martı́nez, E., de Carolis, A. S., & Fuxé, K. (1994) · Neuroreport · doi:10.1097/00001756-199412300-00020 · Cited by 138
Self-citationDimerization and Domain Swapping in G-Protein-Coupled Receptors A Computational Study
Gouldson, P. R., Higgs, C., Smith, R. E., Dean, M. K., Gkoutos, G. V., & Reynolds, C. A. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00153-6 · Cited by 137
Popoli, P. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00256-1 · Cited by 136
Proteomics of the nervous system
Husi, H., & Grant, S. G. N. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01792-6 · Cited by 135
Huntsman, M. M., Tran, B., Potkin, S. G., Bunney, W. E., & Jones, E. G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.15066 · Cited by 134
Protein–protein interfaces: mimics and inhibitors
Cochran, A. G. (2001) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(01)00262-9 · Cited by 133
Domain swapping in G-protein coupled receptor dimers
Gouldson, P. R., Snell, C. R., Bywater, R. P., Higgs, C. J., & Reynolds, C. A. (1998) · Protein Engineering Design and Selection · doi:10.1093/protein/11.12.1181 · Cited by 133
G-protein-independent signaling by G-protein-coupled receptors
Heuss, C., & Gerber, U. R. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01643-x · Cited by 131
Receptor-receptor interactions as an integrative mechanism in nerve cells
Zoli, M., Agnati, L. F., Hedlund, P. B., Li, X., Ferré, S., & Fuxé, K. (1993) · Molecular Neurobiology · doi:10.1007/bf02769180 · Cited by 131
Self-citationAdenosine/dopamine interaction: implications for the treatment of Parkinson's disease
Ferré, S., Popoli, P., Giménez‐Llort, L., Rimondini, R., Müller, C. E., Strömberg, I., Ögren, S. O., & Fuxé, K. (2001) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(00)00063-8 · Cited by 130
Self-citationAspects on receptor regulation and isoreceptor identification.
Agnati, L. F., Fuxé, K., Zini, I., Lenzi, P., & Hökfelt, T. (1980) · PubMed · Cited by 130
Self-citationbeta-FNA binds irreversibly to the opiate receptor complex: in vivo and in vitro evidence.
Rothman, R. B., Long, J. B., Bykov, V., Jacobson, A. E., Rice, K. C., & Holaday, J. W. (1988) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)13379-x · Cited by 129
Cited by
Neve, K. A., Seamans, J. K., & Trantham‐Davidson, H. (2004) · Journal of Receptors and Signal Transduction · doi:10.1081/lrst-200029981 · Cited by 837
Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance
Williams, J. T., Ingram, S. L., Henderson, G., Chavkin, C., von Zastrow, M., Schulz, S., Koch, T., Evans, C. J., & Christie, M. J. (2013) · Pharmacological Reviews · doi:10.1124/pr.112.005942 · Cited by 802
An Update on the Mechanisms of the Psychostimulant Effects of Caffeine
Ferré, S. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05196.x · Cited by 440
Self-citationde la Mora, M. P., Gallegos-Cari, A., Arizmendi-García, Y., Marcellino, D., & Fuxe, K. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.10.010 · Cited by 296
Self-citationA renaissance in trace amines inspired by a novel GPCR family
Lindemann, L., & Hoener, M. C. (2005) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.03.007 · Cited by 287
Metadata
- Authors
- Agnati, L. F., Ferré, S., Lluis, C., Franco, R., & Fuxe, K.
- Venue
- Pharmacological Reviews
- Publisher
- Elsevier BV
- Published
- 2003-09
- Volume
- 55
- Issue
- 3
- Pages
- 509-550
- ISSN
- 0031-6997 (ISSN-L)
- OpenAlex
- W2159797380
- Cited by
- 323
- References
- 360
- FWCI
- 9.97
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.