Evidence that β-Amyloid Protein in Alzheimer's Disease Is Not Derived by Normal Processing

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Trafficking and Proteolytic Processing of APP

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Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor

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Release of Alzheimer Amyloid Precursor Derivatives Stimulated by Activation of Muscarinic Acetylcholine Receptors

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Evidence that production and release of amyloid beta-protein involves the endocytic pathway

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Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.

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The secretases: enzymes with therapeutic potential in Alzheimer disease

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History and progress of hypotheses and clinical trials for Alzheimer’s disease

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Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

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The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway

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Interleukin‐6 and α‐2‐macroglobulin indicate an acute‐phase state in Alzheimer's disease cortices

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LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation

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Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid β peptide in APPswe transgenic mice

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Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative

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Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-β peptide (1–40).

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Metabolism of the “Swedish” Amyloid Precursor Protein Variant in Neuro2a (N2a) Cells

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The cerebrospinal-fluid soluble form of Alzheimer's amyloid β is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

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Post-translational Processing of β-Secretase (β-Amyloid-converting Enzyme) and Its Ectodomain Shedding

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Identification of monocyte chemoattractant protein‐1 in senile plaques and reactive microglia of Alzheimer's disease

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Chemical characterization of A beta 17-42 peptide, a component of diffuse amyloid deposits of Alzheimer disease

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Serotonin 5-HT2a and 5-HT2c Receptors Stimulate Amyloid Precursor Protein Ectodomain Secretion

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The Role of APP Processing and Trafficking Pathways in the Formation of Amyloid β‐Proteina

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Role of microglia in senile plaque formation

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Synaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in the aging cerebral cortex.

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Calcium and Neuronal Injury in Alzheimer's Disease: Contributions of β‐Amyloid Precursor Protein Mismetabolism, Free Radicals, and Metabolic Compromisea

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Nonfibrillar diffuse amyloid deposition due to a gamma42-secretase site mutation points to an essential role for N-truncated Abeta42 in Alzheimer's disease

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Modulation of Statin-Activated Shedding of Alzheimer APP Ectodomain by ROCK

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Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia

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β‐Amyloid Precursor Protein Isoforms in Various Rat Brain Regions and During Brain Development

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Endo‐lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

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Regulation of Amyloid Precursor Protein Catabolism Involves the Mitogen-Activated Protein Kinase Signal Transduction Pathway

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The γ Secretase-generated Carboxyl-terminal Domain of the Amyloid Precursor Protein Induces Apoptosis via Tip60 in H4 Cells

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Amyloidogenesis in familial British dementia is associated with a genetic defect on chromosome 13

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