Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

The Role of Excitatory Amino Acids and NMDA Receptors in Traumatic Brain Injury

Faden, A. I., Demediuk, P., Panter, S. S., & Vink, R. (1989) · Science · doi:10.1126/science.2567056 · Cited by 1,508

Glutamate uptake

Danbolt, N. C. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00067-8 · Cited by 4,227

β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

Rothstein, J. D., Patel, S., Regan, M. R., Haenggeli, C., Huang, Y. H., Bergles, D. E., Jin, L., Dykes Hoberg, M., Vidensky, S., Chung, D. S., et al. (2005) · Nature · doi:10.1038/nature03180 · Cited by 1,518

UNRAVELING THE MECHANISMS INVOLVED IN MOTOR NEURON DEGENERATION IN ALS

Bruijn, L. I., Miller, T. M., & Cleveland, D. W. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144244 · Cited by 1,185

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

Lai, T. W., Zhang, S., & Wang, Y. T. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.11.006 · Cited by 1,106

Cell Biology of Astrocyte-Synapse Interactions

Allen, N. J., & Eroglu, C. (2017) · Neuron · doi:10.1016/j.neuron.2017.09.056 · Cited by 1,098

Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

Sanacora, G., Zarate, C. A., Krystal, J. H., & Manji, H. K. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2462 · Cited by 894

The tripartite synapse: roles for gliotransmission in health and disease

Halassa, M. M., Fellin, T., & Haydon, P. G. (2007) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2006.12.005 · Cited by 852

Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release

Mahmoud, S., Gharagozloo, M., Simard, C., & Gris, D. (2019) · Cells · doi:10.3390/cells8020184 · Cited by 698

(Patho)physiological Significance of the Serum- and Glucocorticoid-Inducible Kinase Isoforms

Lang, F., Böhmer, C., Palmada, M., Seebohm, G., Strutz-Seebohm, N., & Vallon, V. (2006) · Physiological Reviews · doi:10.1152/physrev.00050.2005 · Cited by 689

Heterogeneity of astrocytic form and function.

Oberheim, N. A., Goldman, S. A., & Nedergaard, M. (2012) · Methods in Molecular Biology · doi:10.1007/978-1-61779-452-0_3 · Cited by 638

Glutamate release by primary brain tumors induces epileptic activity

Buckingham, S. C., Campbell, S. L., Haas, B. R., Montana, V., Robel, S., Ogunrinu, T., & Sontheimer, H. (2011) · Nature Medicine · doi:10.1038/nm.2453 · Cited by 578

Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse

Aoyama, K., Suh, S. W., Hamby, A. M., Liu, J., Chan, W. Y., Chen, Y., & Swanson, R. A. (2006) · Nature Neuroscience · doi:10.1038/nn1609 · Cited by 484

The glial glutamate transporter, GLT‐1, is oxidatively modified by 4‐hydroxy‐2‐nonenal in the Alzheimer's disease brain: the role of Aβ1–42

Lauderback, C. M., Hackett, J. M., Huang, F. F., Keller, J. N., Szweda, L. I., Markesbery, W. R., & Butterfield, D. A. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00451.x · Cited by 464

Glial cell abnormalities in major psychiatric disorders: the evidence and implications

Cotter, D. R., Pariante, C. M., & Everall, I. P. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00527-5 · Cited by 465

The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects

Kanai, Y., & Hediger, M. A. (2004) · Pfl�gers Archiv European Journal of Physiology · doi:10.1007/s00424-003-1146-4 · Cited by 450

Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment

Pittenger, C., Bloch, M. H., & Williams, K. (2011) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.09.006 · Cited by 426

Astrocytes in Neurodegenerative Disease: Table 1.

Phatnani, H., & Maniatis, T. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020628 · Cited by 420

The role of astroglia in neuroprotection

Bélanger, M., & Magistretti, P. J. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.3/mbelanger · Cited by 396

Do glia drive synaptic and cognitive impairment in disease?

Chung, W.-S., Welsh, C. A., Barres, B. A., & Stevens, B. (2015) · Nature Neuroscience · doi:10.1038/nn.4142 · Cited by 385

Neuroinflammation and regulation of glial glutamate uptake in neurological disorders

Tilleux, S., & Hermans, E. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21325 · Cited by 381

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

Bernard, R., Kerman, I. A., Thompson, R. C., Jones, E. G., Bunney, W. E., Barchas, J. D., Schatzberg, A. F., Myers, R. M., Akil, H., & Watson, S. J. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.44 · Cited by 372

II. Glutamine and glutamate

Tapiero, H., Mathé, G., Couvreur, P., & Tew, K. D. (2002) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(02)00285-8 · Cited by 369

Reactive astrocytes secrete lcn2 to promote neuron death

Bi, F., Huang, C., Tong, J., Qiu, G., Huang, B., Wu, Q., Li, F., Xu, Z., Bowser, R., Xia, X.-G., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1218497110 · Cited by 371

Astrocyte regulation of synaptic behavior

Allen, N. J. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013053 · Cited by 343

The SLC1 high-affinity glutamate and neutral amino acid transporter family

Kanai, Y., Clémençon, B., Simonin, A., Leuenberger, M., Lochner, M., Weisstanner, M., & Hediger, M. A. (2013) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2013.01.001 · Cited by 329

Glutamate Transporters in Neurologic Disease

Maragakis, N. J., & Rothstein, J. D. (2001) · Archives of Neurology · doi:10.1001/archneur.58.3.365 · Cited by 324

Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease

Osborn, L. M., Kamphuis, W., Wadman, W. J., & Hol, E. M. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2016.01.001 · Cited by 312

Regulation of the glial Na+-dependent glutamate transporters by cyclic AMP analogs and neurons.

Schlag, B. D., Vondrasek, J. R., Munir, M., Kalandadze, A., Zelenaia, O. A., Rothstein, J. D., & Robinson, M. B. (1998) · Molecular Pharmacology · doi:10.1124/mol.53.3.355 · Cited by 303

Conditional Deletion of the Glutamate Transporter GLT-1 Reveals That Astrocytic GLT-1 Protects against Fatal Epilepsy While Neuronal GLT-1 Contributes Significantly to Glutamate Uptake into Synaptosomes

Petr, G. T., Sun, Y., Frederick, N. M., Zhou, Y., Dhamne, S. C., Hameed, M. Q., Miranda, C., Bedoya, E. A., Fischer, K. D., Armsen, W., et al. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.4255-14.2015 · Cited by 297

Inflammation, Glutamate, and Glia in Depression:A Literature Review

McNally, L., Bhagwagar, Z., & Hannestad, J. (2008) · CNS Spectrums · doi:10.1017/s1092852900016734 · Cited by 289

De Novo Mutations in SLC1A2 and CACNA1A Are Important Causes of Epileptic Encephalopathies

Myers, C. T., McMahon, J. M., Schneider, A. L., Petrovski, S., Allen, A. S., Carvill, G. L., Zemel, M., Saykally, J. E., LaCroix, A. J., Heinzen, E. L., et al. (2016) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2016.06.003 · Cited by 287

Astrocytes in the initiation and progression of epilepsy

Vezzani, A., Ravizza, T., Bedner, P., Aronica, E., Steinhäuser, C., & Boison, D. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00727-5 · Cited by 272

Glutamate Transporters and the Excitotoxic Path to Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis

Foran, E., & Trotti, D. (2009) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2444 · Cited by 268

A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: New insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)

Furness, D. N., Dehnes, Y., Akhtar, A. Q., Rossi, D. J., Hamann, M., Grutle, N. J., Gundersen, V., Holmseth, S., Lehre, K. P., Ullensvang, K., et al. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.08.043 · Cited by 254

Surface diffusion of astrocytic glutamate transporters shapes synaptic transmission

Murphy-Royal, C., Dupuis, J. P., Varela, J. A., Panatier, A., Pinson, B., Baufreton, J., Groc, L., & Oliet, S. H. R. (2015) · Nature Neuroscience · doi:10.1038/nn.3901 · Cited by 252

Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1

Yang, Y., Gozen, O., Watkins, A., Lorenzini, I., Lepore, A., Gao, Y., Vidensky, S., Brennan, J., Poulsen, D., Won Park, J., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.02.010 · Cited by 237

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

Tajan, M., Hock, A. K., Blagih, J., Robertson, N. A., Labuschagne, C. F., Kruiswijk, F., Humpton, T. J., Adams, P. D., & Vousden, K. H. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.07.005 · Cited by 230

Astrocytes: Integrative Regulators of Neuroinflammation in Stroke and Other Neurological Diseases

Cekanaviciute, E., & Buckwalter, M. S. (2016) · Neurotherapeutics · doi:10.1007/s13311-016-0477-8 · Cited by 229

Impaired Glutathione Synthesis in Neurodegeneration

Aoyama, K., & Nakaki, T. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms141021021 · Cited by 226

Astrocyte-immune cell interactions in physiology and pathology

Han, R. T., Kim, R. D., Molofsky, A. V., & Liddelow, S. A. (2021) · Immunity · doi:10.1016/j.immuni.2021.01.013 · Cited by 223

Pro-inflammatory cytokines and their effects in the dentate gyrus

Pickering, M., & O’Connor, J. J. (2007) · Progress in Brain Research · doi:10.1016/s0079-6123(07)63020-9 · Cited by 217

Developmental and epileptic encephalopathies: from genetic heterogeneity to phenotypic continuum

Guerrini, R., Conti, V., Mantegazza, M., Balestrini, S., Galanopoulou, A. S., & Benfenati, F. (2023) · Physiological Reviews · doi:10.1152/physrev.00063.2021 · Cited by 196

Amyloid-β 1–42 Slows Clearance of Synaptically Released Glutamate by Mislocalizing Astrocytic GLT-1

Scimemi, A., Meabon, J. S., Woltjer, R. L., Sullivan, J. M., Diamond, J. S., & Cook, D. G. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.5274-12.2013 · Cited by 185

Riluzole in the Treatment of Mood and Anxiety Disorders

Pittenger, C., Coric, V., Banasr, M., Bloch, M., Krystal, J. H., & Sanacora, G. (2008) · CNS Drugs · doi:10.2165/00023210-200822090-00004 · Cited by 177

Glutamate–glutamine cycling in Alzheimer's disease

WALTON, H., & DODD, P. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2006.10.007 · Cited by 174

The Regulation of Astrocytic Glutamate Transporters in Health and Neurodegenerative Diseases

Todd, A. C., & Hardingham, G. E. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249607 · Cited by 172

Excitatory Amino Acid Transporters in Physiology and Disorders of the Central Nervous System

Malik, A. R., & Willnow, T. E. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225671 · Cited by 170

Glutamate neurotransmission in rodent models of traumatic brain injury

Dorsett, C. R., McGuire, J. L., DePasquale, E. A. K., Gardner, A. E., Floyd, C. L., & McCullumsmith, R. E. (2017) · Journal of Neurotrauma · doi:10.1089/neu.2015.4373 · Cited by 163

Role of glutamate excitotoxicity and glutamate transporter EAAT2 in epilepsy: Opportunities for novel therapeutics development

Green, J. L., dos Santos, W. F., & Fontana, A. C. K. (2021) · Biochemical Pharmacology · doi:10.1016/j.bcp.2021.114786 · Cited by 150

Role of Glutamate Transporters in the Clearance and Release of Glutamate during Ischemia and its Relation to Neuronal Death

Camacho, A., & Massieu, L. (2006) · Archives of Medical Research · doi:10.1016/j.arcmed.2005.05.014 · Cited by 150

Glutamate Release Monitored with Astrocyte Transporter Currents during LTP

Diamond, J. S., Bergles, D. E., & Jahr, C. E. (1998) · Neuron · doi:10.1016/s0896-6273(00)80551-6 · Cited by 143

Glial Dysfunction in the Mouse Habenula Causes Depressive-Like Behaviors and Sleep Disturbance

Cui, W., Mizukami, H., Yanagisawa, M., Aida, T., Nomura, M., Isomura, Y., Takayanagi, R., Ozawa, K., Tanaka, K., & Aizawa, H. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1465-14.2014 · Cited by 139

Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain

Bonansco, C., & Fuenzalida, M. (2016) · Neural Plasticity · doi:10.1155/2016/8607038 · Cited by 138

Glutamate Clearance Is Locally Modulated by Presynaptic Neuronal Activity in the Cerebral Cortex

Armbruster, M., Hanson, E., & Dulla, C. G. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.2066-16.2016 · Cited by 131

Increased expression of the astrocytic glutamate transporter GLT‐1 in the prefrontal cortex of schizophrenics

Matute, C., Melone, M., Vallejo‐Illarramendi, A., & Conti, F. (2005) · Glia · doi:10.1002/glia.20119 · Cited by 129

Heterogeneity of Astrocytes in Grey and White Matter

Köhler, S., Winkler, U., & Hirrlinger, J. (2021) · Neurochemical Research · doi:10.1007/s11064-019-02926-x · Cited by 123

Structural plasticity and tianeptine: cellular and molecular targets

McEwen, B. S., Magarinos, A. M., & Reagan, L. P. (2002) · European Psychiatry · doi:10.1016/s0924-9338(02)00650-8 · Cited by 108

Astrocyte–neuron interplay in maladaptive plasticity.

Papa, M., De Luca, C., Petta, F., Alberghina, L., & Cirillo, G. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.01.010 · Cited by 104

Selective deletion of astroglial FMRP dysregulates glutamate transporter GLT1 and contributes to fragile X syndrome phenotypes in vivo.

Higashimori, H., Schin, C. S., Chiang, M. S. R., Morel, L., Shoneye, T. A., Nelson, D. L., & Yang, Y. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1069-16.2016 · Cited by 105

Pathogenetic mechanisms of focal cortical dysplasia

Marin‐Valencia, I., Guerrini, R., & Gleeson, J. G. (2014) · Epilepsia · doi:10.1111/epi.12650 · Cited by 100

Antidepressants act on glial cells: SSRIs and serotonin elicit astrocyte calcium signaling in the mouse prefrontal cortex

Schipke, C. G., Heuser, I., & Peters, O. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.06.005 · Cited by 98

Thyroid hormone increases astrocytic glutamate uptake and protects astrocytes and neurons against glutamate toxicity

Mendes‐de‐Aguiar, C. B. N., Alchini, R., Decker, H., Alvarez‐Silva, M., Tasca, C. I., & Trentin, A. G. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21755 · Cited by 92

Divergent roles of astrocytic versus neuronal EAAT2 deficiency on cognition and overlap with aging and Alzheimer’s molecular signatures

Sharma, A., Kazim, S. F., Larson, C. S., Ramakrishnan, A., Gray, J. D., McEwen, B. S., Rosenberg, P. A., Shen, L., & Pereira, A. C. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1903566116 · Cited by 92

Metabolic pathways and activity-dependent modulation of glutamate concentration in the human brain

Mangia, S., Giove, F., & DiNuzzo, M. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0848-4 · Cited by 90

Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients

Cavus, I., Pan, J. W., Hetherington, H. P., Abi‐Saab, W., Zaveri, H. P., Vives, K. P., Krystal, J. H., Spencer, S. S., & Spencer, D. D. (2008) · Epilepsia · doi:10.1111/j.1528-1167.2008.01603.x · Cited by 89

Ceftriaxone increases glutamate uptake and reduces striatal tyrosine hydroxylase loss in 6-OHDA Parkinson's model

Chotibut, T., Davis, R. W., Arnold, J. C., Frenchek, Z., Gurwara, S., Bondada, V., Geddes, J. W., & Salvatore, M. F. (2014) · Molecular Neurobiology · doi:10.1007/s12035-013-8598-0 · Cited by 86

Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse.

Higashimori, H., Morel, L., Huth, J., Lindemann, L., Dulla, C., Taylor, A., Freeman, M., & Yang, Y. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt055 · Cited by 85

Maternal inflammation leads to impaired glutamate homeostasis and up-regulation of glutamate carboxypeptidase II in activated microglia in the fetal/newborn rabbit brain

Zhang, Z., Bassam, B., Thomas, A. G., Williams, M., Liu, J., Nance, E., Rojas, C., Slusher, B. S., & Kannan, S. (2016) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.06.010 · Cited by 84

Time-dependent modulation of AMPA receptor phosphorylation and mRNA expression of NMDA receptors and glial glutamate transporters in the rat hippocampus and cerebral cortex in a pilocarpine model of epilepsy

Lopes, M. W., Soares, F. M. S., de Mello, N., Nunes, J. C., Cajado, A. G., de Brito, D., de Cordova, F. M., da Cunha, R. M. S., Walz, R., & Leal, R. B. (2013) · Experimental Brain Research · doi:10.1007/s00221-013-3421-8 · Cited by 78

Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta

Yan, X., Jiang, E., & Weng, H.-R. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-014-0222-3 · Cited by 77

Localization of excitatory amino acid transporters EAAT1 and EAAT2 in human postmortem cortex: A light and electron microscopic study

Roberts, R. C., Roche, J. K., & McCullumsmith, R. E. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.07.019 · Cited by 76

Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder

Veenstra-VanderWeele, J., Kim, S.-J., Gonen, D., Hanna, G. L., Leventhal, B. L., & Cook, E. H. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000806 · Cited by 74

Astrocytes and Glutamine Synthetase in Epileptogenesis

Eid, T., Lee, T. W., Patrylo, P., & Zaveri, H. P. (2019) · Journal of Neuroscience Research · doi:10.1002/jnr.24267 · Cited by 74

Impaired glutamate recycling and GluN2B‐mediated neuronal calcium overload in mice lacking TGF‐β1 in the CNS

Koeglsperger, T., Li, S., Brenneis, C., Saulnier, J. L., Mayo, L., Carrier, Y., Selkoe, D. J., & Weiner, H. L. (2013) · Glia · doi:10.1002/glia.22490 · Cited by 73

Molecular changes evoked by the beta-lactam antibiotic ceftriaxone across rodent models of substance use disorder and neurological disease

Smaga, I., Fierro, D., Mesa, J., Filip, M., & Knackstedt, L. A. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.05.016 · Cited by 69

GABA release from astrocytes in health and disease.

Kilb, W., & Kirischuk, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415859 · Cited by 66

General Pathophysiology of Astroglia

Verkhratsky, A., Ho, M. S., Vardjan, N., Zorec, R., & Parpura, V. (2019) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-13-9913-8_7 · Cited by 66

Ceftriaxone Prevents and Reverses Behavioral and Neuronal Deficits in an MPTP-Induced Animal Model of Parkinson’s Disease Dementia

Hsu, C.-Y., Hung, C.-S., Chang, H.-M., Liao, W.-C., Ho, S.-C., & Ho, Y.-J. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.11.023 · Cited by 63

The Role of Glial Cell Senescence in Alzheimer's Disease

Alshaebi, F., Sciortino, A., & Kayed, R. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70051 · Cited by 60

Dysfunction of astrocytic connexins 30 and 43 in the medial prefrontal cortex and hippocampus mediates depressive-like behaviours

Huang, D., Li, C., Zhang, W., Qin, J., Jiang, W., & Hu, C. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.111950 · Cited by 59

Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus

Krzisch, M., Temprana, S. G., Mongiat, L. A., Armida, J., Schmutz, V., Virtanen, M. A., Kocher-Braissant, J., Kraftsik, R., Vutskits, L., Conzelmann, K.-K., et al. (2015) · Brain Structure and Function · doi:10.1007/s00429-014-0768-y · Cited by 57

Proteome Analysis and Conditional Deletion of the EAAT2 Glutamate Transporter Provide Evidence against a Role of EAAT2 in Pancreatic Insulin Secretion in Mice

Zhou, Y., Waanders, L. F., Holmseth, S., Guo, C., Berger, U. V., Li, Y., Lehre, A.-C., Lehre, K. P., & Danbolt, N. C. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.529065 · Cited by 49

Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin

Sugiyama, T., Sadzuka, Y., Tanaka, K., & Sonobe, T. (2001) · Toxicology Letters · doi:10.1016/s0378-4274(01)00317-4 · Cited by 47

Amyloid-beta peptide decreases expression and function of glutamate transporters in nervous system cells

Tong, H., Zhang, X., Meng, X., Xu, P., Zou, X., & Qu, S. (2017) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2017.01.017 · Cited by 42

Chronic stress and lithium treatments alter hippocampal glutamate uptake and release in the rat and potentiate necrotic cellular death after oxygen and glucose deprivation

de Vasconcellos-Bittencourt, A. P. S., Vendite, D. A., Nassif, M., Crema, L. M., Frozza, R., Thomazi, A. P., Nieto, F. B., Wofchuk, S., Salbego, C., da Rocha, E. R., et al. (2011) · Neurochemical Research · doi:10.1007/s11064-011-0404-7 · Cited by 36

Common and divergent pathways in early stages of glutamate and tau-mediated toxicities in neurodegeneration

Chongtham, A., Sharma, A., Nath, B., Murtha, K., Gorbachev, K., Ramakrishnan, A., Schmidt, E. F., Shen, L., & Pereira, A. C. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.114967 · Cited by 10

Gene variations of glutamate metabolism pathway and epilepsy

Feng, Y., Zhang, C., Wei, Z., Li, G., Gan, Y., Liu, C., & Deng, Y. (2022) · Acta Epileptologica · doi:10.1186/s42494-022-00103-2 · Cited by 10