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Adolescent Changes in the Homeostatic and Circadian Regulation of Sleep
Open accessAbstract
Sleep deprivation among adolescents is epidemic. We argue that this sleep deprivation is due in part to pubertal changes in the homeostatic and circadian regulation of sleep. These changes promote a delayed sleep phase that is exacerbated by evening light exposure and incompatible with aspects of modern society, notably early school start times. In this review of human and animal literature, we demonstrate that delayed sleep phase during puberty is likely a common phenomenon in mammals, not specific to human adolescents, and we provide insight into the mechanisms underlying this phenomenon.
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“For pubertal mice, this tendency was exaggerated, with the animals being clearly more sensitive to evening light than adults [70, 198].”
From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [70]
In the citing paper
“Reduced sensitivity to the homeostatic sleep drive that builds during extended wakefulness may also contribute to later bedtimes in adolescents (Hagenauer, Perryman, Lee, & Carskadon, 2009).”
From Sleep and circadian contributions to adolescent alcohol use disorder (2015) · cites this paper as Hagenauer et al., 2009
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Metadata
- Authors
- Hagenauer, M. H., Perryman, J. I., Lee, T. M., & Carskadon, M. A.
- Affiliations
- University of Michigan (US)
- Brown University (US)
- Venue
- Developmental Neuroscience
- Publisher
- S. Karger AG
- Published
- 2009
- Volume
- 31
- Issue
- 4
- Pages
- 276-284
- ISSN
- 0378-5866 (ISSN-L)
- 1421-9859
- PMC
- PMC2820578
- OpenAlex
- W2032467619
- Cited by
- 593
- References
- 67
- Citations by year
- 2026: 42 · 2025: 40 · 2024: 32 · 2023: 34 · 2022: 55 · 2021: 49 · 2020: 53 · 2019: 31 · 2018: 59 · 2017: 44 · 2016: 21 · 2015: 31 · 2014: 28 · 2013: 22 · 2012: 17
- FWCI
- 1.91
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Developmental Neuroscience (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Funders
- National Science Foundation
- National Institutes of Health (5k05mh001358-03, 5r01nr004279-04)
- National Institute of Mental Health (R01MH045945, MH52415, MH01358, R01MH052415, R01MH076969, MH076969)
- National Institute of Nursing Research (NR04279)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (T32HD007048)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- adolescent sleep, sleep deprivation, pubertal development, sleep homeostasis, circadian rhythm, delayed sleep phase, evening light exposure, school start time, mammals
- MeSH terms
- Adolescent, Adolescent Behavior, Animals, Biological Clocks, Circadian Rhythm, Female, Homeostasis, Humans, Light, Male, Puberty, Sleep, Sleep Deprivation, Photoperiod, Gonadal Hormones
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