Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, Maj-Linda B., Brownlow, Milene, Jimenez, Jeffy P., Lee, Daniel C., Pena, Gabriela, Dickey, Chad A., Gordon, Marcia N., Morgan, Dave·2013·Neurodegenerative Diseases

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  2. β-Amyloid Immunotherapy Prevents Synaptic Degeneration in a Mouse Model of Alzheimer's Disease
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  3. Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
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  6. A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease
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  7. Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons
    Quintanilla, Rodrigo A., Matthews-Roberson, Tori A., Dolan, Philip J., Johnson, Gail V.W. · 2009 · Journal of Biological Chemistry
  8. PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.
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  9. Resveratrol Brain Delivery for Neurological Disorders Prevention and Treatment
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  10. Relative incidence of seizures and myoclonus in Alzheimer’s disease, dementia with lewy bodies, and frontotemporal dementia.
    Beagle, Alexander J., Darwish, Sonja M., Ranasinghe, Kamalini G., La, Alice L., Karageorgiou, Elissaios, Vossel, Keith A. · 2017 · Journal of Alzheimer's Disease
  11. Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice
    NELSON, R, GUO, Z, HALAGAPPA, V, PEARSON, M, GRAY, A, MATSUOKA, Y, BROWN, M, MARTIN, B, IYUN, T, MAUDSLEY, S · 2007 · Experimental Neurology
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  13. Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment
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  16. Nonhuman Primate Models of Alzheimer-Like Cerebral Proteopathy
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  17. Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain
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  19. Tau Oligomers: The Toxic Player at Synapses in Alzheimer’s Disease
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  20. Tau exacerbates excitotoxic brain damage in an animal model of stroke
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  21. Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β
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  22. Blocking the apolipoprotein E/amyloid-β interaction as a potential therapeutic approach for Alzheimer's disease
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  25. Molecular diagnostics of neurodegenerative disorders
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  26. Neuropathology of mood disorders: Do we see the stigmata of inflammation?
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  27. Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice
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  28. Antisense oligonucleotides: treating neurodegeneration at the level of RNA
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  35. Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer’s Disease.
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  36. Role of TGFβ signaling in the pathogenesis of Alzheimer’s disease
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  38. GSK3β and tau protein in Alzheimer's disease and epilepsy
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  42. Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice
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  43. Animal models of Alzheimer’s disease: Applications, evaluation, and perspectives
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  47. Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein
    Harris, Julie A., Devidze, Nino, Halabisky, Brian, Lo, Iris, Thwin, Myo T., Yu, Gui-Qiu, Bredesen, Dale E., Masliah, Eliezer, Mucke, Lennart · 2010 · The Journal of Neuroscience
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  52. TREM2 is associated with increased risk for Alzheimer’s disease in African Americans
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  55. RNA binding proteins co-localize with small tau inclusions in tauopathy
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  56. Spreading of Tau Pathology in Sporadic Alzheimer’s Disease Along Cortico-cortical Top-Down Connections
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  60. UB‐311, a novel UBITh <sup>®</sup> amyloid β peptide vaccine for mild Alzheimer's disease
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  66. Drug development for Alzheimer's disease: where are we now and where are we headed?
    Sabbagh, Marwan N. · 2009 · ˜The œAmerican journal of geriatric pharmacotherapy
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