Unraveling the Mechanisms Responsible for the Comorbidity between Metabolic Syndrome and Mental Health Disorders

Nousen, Elizabeth K.; Franco, Juliana G.; Sullivan, Elinor L.

doi:10.1159/000355632

Cited by 123Tryptophan and brain disordersAdipokines, Inflammation, and Metabolic DiseasesStress Responses and Cortisol

Unraveling the Mechanisms Responsible for the Comorbidity between Metabolic Syndrome and Mental Health Disorders

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Nousen, Elizabeth K., Franco, Juliana G., Sullivan, Elinor L.·2013·Neuroendocrinology

DOI 10.1159/000355632PMC PMC4121390

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Abstract

The increased prevalence and high comorbidity of metabolic syndrome (MetS) and mental health disorders (MHDs) have prompted investigation into the potential contributing mechanisms. There is a bidirectional association between MetS and MHDs including schizophrenia, bipolar disorder, depression, anxiety, attention-deficit/hyperactivity disorder, and autism spectrum disorders. Medication side effects and social repercussions are contributing environmental factors, but there are a number of shared underlying neurological and physiological mechanisms that explain the high comorbidity between these two disorders. Inflammation is a state shared by both disorders, and it contributes to disruptions of neuroregulatory systems (including the serotonergic, dopaminergic, and neuropeptide Y systems) as well as dysregulation of the hypothalamic-pituitary-adrenal axis. MetS in pregnant women also exposes the developing fetal brain to inflammatory factors that predispose the offspring to MetS and psychopathologies. Due to the shared nature of these conditions, treatment should address aspects of both mental health and metabolic disorders. Additionally, interventions that can interrupt the transfer of increased risk of the disorders to the next generation need to be developed.

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Maternal metabolic disorders including diabetes and obesity can pose another threat to the unborn child as placental dysfunctioning alters the prenatal exposure to nutrients and toxins.
“Maternal metabolic disorders including diabetes and obesity can pose another threat to the unborn child as placental dysfunctioning alters the prenatal exposure to nutrients and toxins [312–314].”
From Development of prefrontal cortex (2022) · cites this paper as [313]
The Placental Dysfunction section links gestational diabetes and obesity to placental inflammation and impaired function. Alternate Mechanisms of Maternal Programming reports excess nutrient exposure in offspring of obese mothers and says maternal glucose passes through the placenta. The paper does not say placental dysfunction alters fetal exposure to toxins, or clearly attribute the excess nutrient exposure to that dysfunction. (LLM, conf=0.87)
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Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052 · see citing works
The metabolic syndrome—a new worldwide definition
Alberti, K. G. M., Zimmet, P., & Shaw, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67402-8 · Cited by 9,352 · see citing works
Prevalence of Overweight and Obesity in the United States, 1999-2004
Ogden, C. L., Carroll, M. D., Curtin, L. R., McDowell, M. A., Tabak, C. J., & Flegal, K. M. (2006) · JAMA · doi:10.1001/jama.295.13.1549 · Cited by 8,720 · see citing works
Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010.
Flegal, K., Carroll, M., Kit, B., & Ogden, C. (2012) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.2012.39 · Cited by 5,523 · see citing works
Overweight, Obesity, and Depression: A Systematic Review and Meta-analysis of Longitudinal Studies
Luppino, F. S., de Wit, L. M., Bouvy, P. F., Stijnen, T., Cuijpers, P., Penninx, B. W. J. H., & Zitman, F. G. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.2 · Cited by 4,322 · see citing works
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426 · see citing works
Antipsychotic-induced weight gain: a comprehensive research synthesis
Allison, D. B., Mentore, J. L., Heo, M., Chandler, L. P., Cappelleri, J. C., Infante, M. C., & Weiden, P. J. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.11.1686 · Cited by 2,382 · see citing works
Prevalence of a Metabolic Syndrome Phenotype in Adolescents: Findings From the Third National Health and Nutrition Examination Survey, 1988-1994
Cook, S., Weitzman, M., Auinger, P., Nguyen, M., & Dietz, W. H. (2003) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.157.8.821 · Cited by 2,326 · see citing works
The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors
Thayer, J. F., Yamamoto, S. S., & Brosschot, J. F. (2010) · International Journal of Cardiology · doi:10.1016/j.ijcard.2009.09.543 · Cited by 2,276 · see citing works
A comprehensive definition for metabolic syndrome
Huang, P. L. (2009) · Disease Models & Mechanisms · doi:10.1242/dmm.001180 · Cited by 2,223 · see citing works
Brain dopamine and obesity
Wang, G.-J., Volkow, N. D., Logan, J., Pappas, N. R., Wong, C. T., Zhu, W., Netusll, N., & Fowler, J. S. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03643-6 · Cited by 1,864 · see citing works
Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors
Pazos, Á., & Palacios, J. M. (1985) · Brain Research · doi:10.1016/0006-8993(85)90856-x · Cited by 1,855 · see citing works
Stress, eating and the reward system
Adam, T. C., & Epel, E. S. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.04.011 · Cited by 1,732 · see citing works
Trends in the prevalence of developmental disabilities in US children, 1997-2008
Boyle, C. A., Boulet, S., Schieve, L. A., Cohen, R. A., Blumberg, S. J., Yeargin-Allsopp, M., Visser, S., & Kogan, M. D. (2011) · Pediatrics · doi:10.1542/peds.2010-2989 · Cited by 1,732 · see citing works
Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6
Smith, S. E. P., Li, J., Garbett, K., Mirnics, K., & Patterson, P. H. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2178-07.2007 · Cited by 1,605 · see citing works
Depression and Type 2 Diabetes Over the Lifespan
Mezuk, B., Eaton, W. W., Albrecht, S., & Golden, S. H. (2008) · Diabetes Care · doi:10.2337/dc08-0985 · Cited by 1,558 · see citing works
Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients
Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485 · see citing works
The role of corticotropin-releasing factor in depression and anxiety disorders
Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378 · see citing works
Association between obesity and psychiatric disorders in the US adult population
Simon, G. E., Von Korff, M., Saunders, K., Miglioretti, D. L., Crane, P. K., van Belle, G., & Kessler, R. C. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.7.824 · Cited by 1,338 · see citing works
Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence
Boyle, J. P., Thompson, T. J., Gregg, E. W., Barker, L. E., & Williamson, D. F. (2010) · Population Health Metrics · doi:10.1186/1478-7954-8-29 · Cited by 1,309 · see citing works
Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis
Kemp, A. H., Quintana, D. S., Gray, M. A., Felmingham, K. L., Brown, K., & Gatt, J. M. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.12.012 · Cited by 1,286 · see citing works
Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
Tecott, L. H., Sun, L. M., Akana, S. F., Strack, A. M., Lowenstein, D. H., Dallman, M. F., & Julius, D. J. (1995) · Nature · doi:10.1038/374542a0 · Cited by 1,275 · see citing works
Relationships between obesity and DSM-IV major depressive disorder, suicide ideation, and suicide attempts: results from a general population study
Carpenter, K. M., Hasin, D. S., Allison, D. B., & Faith, M. S. (2000) · American Journal of Public Health · doi:10.2105/ajph.90.2.251 · Cited by 1,018 · see citing works
Fetal Origins of Obesity
Oken, E., & Gillman, M. W. (2003) · Obesity Research · doi:10.1038/oby.2003.69 · Cited by 929 · see citing works
Is Obesity Associated with Major Depression? Results from the Third National Health and Nutrition Examination Survey
Onyike, C. U. (2003) · American Journal of Epidemiology · doi:10.1093/aje/kwg275 · Cited by 827 · see citing works
Depression and obesity
Stunkard, A. J., Faith, M. S., & Allison, K. C. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00608-5 · Cited by 820 · see citing works
Is obesity an inflammatory condition?
Das, U. N. (2001) · Nutrition · doi:10.1016/s0899-9007(01)00672-4 · Cited by 799 · see citing works
Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis
for the European Depression in Diabetes (EDID) Research Consortium, Nouwen, A., Winkley, K., Twisk, J., Lloyd, C. E., Peyrot, M., Ismail, K., & Pouwer, F. (2010) · Diabetologia · doi:10.1007/s00125-010-1874-x · Cited by 756 · see citing works
Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic
Zhou, Q.-Y., & Palmiter, R. D. (1995) · Cell · doi:10.1016/0092-8674(95)90145-0 · Cited by 731 · see citing works
Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta
Challier, J. C., Basu, S., Bintein, T., Minium, J., Hotmire, K., Catalano, P. M., & Hauguel-de Mouzon, S. (2008) · Placenta · doi:10.1016/j.placenta.2007.12.010 · Cited by 712 · see citing works
Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders
Krakowiak, P., Walker, C. K., Bremer, A. A., Baker, A. S., Ozonoff, S., Hansen, R. L., & Hertz-Picciotto, I. (2012) · PEDIATRICS · doi:10.1542/peds.2011-2583 · Cited by 675 · see citing works
Prospective association between obesity and depression: evidence from the Alameda County Study
Roberts, R. E., Deleger, S., Strawbridge, W. J., & Kaplan, G. A. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802204 · Cited by 674 · see citing works
Increased Numbers of Corticotropin-Releasing Hormone Expressing Neurons in the Hypothalamic Paraventricular Nucleus of Depressed Patients
Raadsheer, F. C., Hoogendijk, W. J. G., Stam, F. C., Tilders, F. J. H., & Swaab, D. F. (2008) · Neuroendocrinology · doi:10.1159/000126778 · Cited by 667 · see citing works
Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia
Fillman, S. G., Cloonan, N., Catts, V. S., Miller, L. C., Wong, J., McCrossin, T., Cairns, M., & Weickert, C. S. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.110 · Cited by 609 · see citing works
Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors
Volkow, N. D., Wang, G.-J., Telang, F., Fowler, J. S., Thanos, P. K., Logan, J., Alexoff, D., Ding, Y.-S., Wong, C., Ma, Y., et al. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.06.002 · Cited by 573 · see citing works
Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes
Vucetic, Z., Kimmel, J. N., Totoki, K., Hollenbeck, E., & Reyes, T. M. (2010) · Endocrinology · doi:10.1210/en.2010-0505 · Cited by 556 · see citing works
Reduced Corticotropin Releasing Factor Binding Sites in the Frontal Cortex of Suicide Victims
Nemeroff, C. B. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800300075009 · Cited by 555 · see citing works
Comparative localization of serotonin1A, 1C, and 2 receptor subtype mRNAs in rat brain
Wright, D. E., Seroogy, K. B., Lundgren, K. H., Davis, B. M., & Jennes, L. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903510304 · Cited by 548 · see citing works
The relationship between mental and physical health: insights from the study of heart rate variability
Kemp, A. H., & Quintana, D. S. (2013) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2013.06.018 · Cited by 538 · see citing works
Inflammatory markers and depressed mood in older persons: results from the health, aging and body composition study
Penninx, B. W. J. H., Kritchevsky, S. B., Yaffe, K. S., Newman, A. B., Simonsick, E. M., Rubin, S. M., Ferrucci, L., Harris, T. B., & Pahor, M. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01811-5 · Cited by 530 · see citing works
Binge eating disorder and obesity
de Zwaan, M. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801699 · Cited by 522 · see citing works
Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene
Gray, J. A., Yeo, G. S. H., Cox, J. J., Morton, J., Adlam, A., Keogh, J. M., Yanovski, J. A., Gharbawy, A. E., Han, J. C., Tung, Y. C. L., et al. (2006) · Diabetes · doi:10.2337/db06-0550 · Cited by 515 · see citing works
Prevalence and Trends of a Metabolic Syndrome Phenotype Among U.S. Adolescents, 1999–2000
Duncan, G. E., Li, S. M., & Zhou, X. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2438 · Cited by 495 · see citing works
Overweight and Obesity Are Associated With Psychiatric Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions
Petry, N. M., Barry, D., Pietrzak, R. H., & Wagner, J. A. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181651651 · Cited by 494 · see citing works
Enduring consequences of maternal obesity for brain inflammation and behavior of offspring
Bilbo, S. D., & Tsang, V. (2010) · The FASEB Journal · doi:10.1096/fj.09-144014 · Cited by 489 · see citing works
Levels and risks of depression and anxiety symptomatology among diabetic adults
Peyrot, M., & Rubin, R. R. (1997) · Diabetes Care · doi:10.2337/diacare.20.4.585 · Cited by 488 · see citing works
Obesity and mental disorders in the general population: results from the world mental health surveys
Scott, K. M., Bruffaerts, R., Simon, G. E., Alonso, J., Angermeyer, M. C., de Girolamo, G., Demyttenaere, K., Gasquet, I., Haro, J. M., Karam, E. G., et al. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803701 · Cited by 483 · see citing works
Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene
Nonogaki, K., Strack, A. M., Dallman, M. F., & Tecott, L. H. (1998) · Nature Medicine · doi:10.1038/2647 · Cited by 467 · see citing works
Bidirectional Association Between Depression and Type 2 Diabetes Mellitus in Women
Pan, A., Lucas, M., Sun, Q., van Dam, R. M., Franco, O. H., Manson, J. E., Willett, W. C., Ascherio, A., & Hu, F. B. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.356 · Cited by 447 · see citing works
Associations between obesity and comorbid mental health, developmental, and physical health conditions in a nationally representative sample of us children aged 10 to 17
Halfon, N., Larson, K., & Slusser, W. (2013) · Academic Pediatrics · doi:10.1016/j.acap.2012.10.007 · Cited by 429 · see citing works
Heartache and heartbreak—the link between depression and cardiovascular disease
Nemeroff, C. B., & Goldschmidt-Clermont, P. J. (2012) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2012.91 · Cited by 424 · see citing works
Depression and anxiety among US adults: associations with body mass index
Zhao, G., Ford, E. S., Dhingra, S., Li, C., Strine, T. W., & Mokdad, A. H. (2009) · International Journal of Obesity · doi:10.1038/ijo.2008.268 · Cited by 423 · see citing works
The neuropoietic cytokine family in development, plasticity, disease and injury
Bauer, Š., Kerr, B. J., & Patterson, P. H. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2054 · Cited by 412 · see citing works
Obesity among those with mental disorders: a National Institute of Mental Health meeting report.
Allison, D., Newcomer, J., Dunn, A., Blumenthal, J., Fabricatore, A., Daumit, G., Cope, M., Riley, W., Vreeland, B., Hibbeln, J., et al. (2009) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2008.11.020 · Cited by 411 · see citing works
Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models
Heilig, M. A., S�derpalm, B., Engel, J. A., & Widerl�v, E. (1989) · Psychopharmacology · doi:10.1007/bf00441953 · Cited by 390 · see citing works
Gestational Diabetes Induces Placental Genes for Chronic Stress and Inflammatory Pathways
Radaelli, T., Varastehpour, A., Catalano, P., & Hauguel-de Mouzon, S. (2003) · Diabetes · doi:10.2337/diabetes.52.12.2951 · Cited by 390 · see citing works
Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation
Deng, T., Lyon, C. J., Minze, L. J., Lin, J., Zou, J., Liu, J. Z., Ren, Y., Yin, Z., Hamilton, D. J., Reardon, P. R., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.02.009 · Cited by 382 · see citing works
Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications
Alesci, S., Martinez, P. E., Kelkar, S., Ilias, I., Ronsaville, D. S., Listwak, S. J., Ayala, A. R., Licinio, J., Gold, H. K., Kling, M. A., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1667 · Cited by 372 · see citing works
Selective Deletion ofBdnfin the Ventromedial and Dorsomedial Hypothalamus of Adult Mice Results in Hyperphagic Behavior and Obesity
Unger, T. J., Calderon, G. A., Bradley, L., Sena‐Esteves, M., & Rios, M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3308-07.2007 · Cited by 370 · see citing works
Obesity and obesity‐related secondary conditions in adolescents with intellectual/developmental disabilities
Rimmer, J. H., Yamaki, K., Lowry, B. M. D., Wang, E., & Vogel, L. C. (2010) · Journal of Intellectual Disability Research · doi:10.1111/j.1365-2788.2010.01305.x · Cited by 354 · see citing works
Brain Serotonin and Dopamine Transporter Bindings in Adults With High-Functioning Autism
Nakamura, K., Sekine, Y., Ouchi, Y., Tsujii, M., Yoshikawa, E., Futatsubashi, M., Tsuchiya, K. J., Sugihara, G., Iwata, Y., Suzuki, K., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.137 · Cited by 352 · see citing works
Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study
Goines, P. E., Croen, L. A., Braunschweig, D., Yoshida, C. K., Grether, J., Hansen, R., Kharrazi, M., Ashwood, P., & Van de Water, J. (2011) · Molecular Autism · doi:10.1186/2040-2392-2-13 · Cited by 351 · see citing works
Association Between Depression and Elevated C-Reactive Protein
Danner, M., Kasl, S. V., Abramson, J. L., & Vaccarino, V. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000041542.29808.01 · Cited by 341 · see citing works
The association between burnout, depression, anxiety, and inflammation biomarkers: C-reactive protein and fibrinogen in men and women
Toker, S., Shirom, A., Shapira, I., Berliner, S., & Melamed, S. (2005) · Journal of Occupational Health Psychology · doi:10.1037/1076-8998.10.4.344 · Cited by 340 · see citing works
IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation
Wei, H., Zou, H., Sheikh, A. M., Malik, M., Dobkin, C., Brown, W. T., & Li, X. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-52 · Cited by 333 · see citing works
Depressive mood and obesity in US adults: comparison and moderation by sex, age, and race
Heo, M., Pietrobelli, A., Fontaine, K. R., Sirey, J. A., & Faith, M. S. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803122 · Cited by 331 · see citing works
Inflammatory markers in late-life depression: Results from a population-based study
Bremmer, M. A., Beekman, A. T. F., Deeg, D. J. H., Penninx, B. W. J. H., Dik, M. G., Hack, C. E., & Hoogendijk, W. J. G. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.07.002 · Cited by 326 · see citing works
Chronic Consumption of a High-Fat Diet during Pregnancy Causes Perturbations in the Serotonergic System and Increased Anxiety-Like Behavior in Nonhuman Primate Offspring
Sullivan, E. L., Grayson, B. E., Takahashi, D. L., Robertson, N. D., Maier, A., Bethea, C. L., Smith, M. S., Coleman, K., & Grove, K. L. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5560-09.2010 · Cited by 324 · see citing works
Self-citation
Association of depressive disorders, depression characteristics and antidepressant medication with inflammation
Vogelzangs, N., Duivis, H. E., Beekman, A. T. F., Kluft, C., Neuteboom, J., Hoogendijk, W., Smit, J. H., de Jonge, P., & Penninx, B. W. J. H. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.8 · Cited by 323 · see citing works
Behavioral studies following lesions of the mesolimbic and mesostriatal serotonergic pathways
Geyer, M. A., Puerto, A., Menkes, D. B., Segal, D. S., & Mandell, A. J. (1976) · Brain Research · doi:10.1016/0006-8993(76)91024-6 · Cited by 313 · see citing works
Discrete neurochemical coding of distinguishable motivational processes: insights from nucleus accumbens control of feeding
Baldo, B. A., & Kelley, A. E. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0741-z · Cited by 312 · see citing works
Overweight in Children and Adolescents in Relation to Attention-Deficit/Hyperactivity Disorder: Results From a National Sample
Waring, M. E., & Lapane, K. L. (2008) · Pediatrics · doi:10.1542/peds.2007-1955 · Cited by 294 · see citing works
Association of Interleukin‐6 and Other Biologic Variables with Depression in Older People Living in the Community
Dentino, A. N., Pieper, C. F., Rao, K. M. K., Currie, M. S., Harris, T., Blazer, D. G., & Cohen, H. J. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb01894.x · Cited by 287 · see citing works
Maternal adiposity prior to pregnancy is associated with ADHD symptoms in offspring: evidence from three prospective pregnancy cohorts
Rodriguez, A., Miettunen, J., Henriksen, T. B., Olsen, J., Obel, C., Taanila, A. M., Ebeling, H. E., Línnet, K., Moilanen, I., & Järvelin, M. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803741 · Cited by 282 · see citing works
Prevalence of mental disorder in 88 morbidly obese bariatric clinic patients
Black, D. W., Goldstein, R. B., & Mason, E. E. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.2.227 · Cited by 281 · see citing works
Placental structure and inflammation in pregnancies associated with obesity
Roberts, K., Riley, S. C., Reynolds, R. M., Barr, S., Evans, M., Statham, A., Hor, K., Jabbour, H. N., Norman, J. E., & Denison, F. C. (2011) · Placenta · doi:10.1016/j.placenta.2010.12.023 · Cited by 281 · see citing works
Altered T cell responses in children with autism
Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I. N., & Van de Water, J. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.09.002 · Cited by 281 · see citing works
Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders
Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I. N., & Van de Water, J. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.10.025 · Cited by 279 · see citing works
Role of Dopamine Receptors in ADHD: A Systematic Meta-analysis
Wu, J., Xiao, H., Sun, H., Zou, L., & Zhu, L.-Q. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8278-5 · Cited by 274 · see citing works
Maternal High-Fat Diet Disturbs Uteroplacental Hemodynamics and Increases the Frequency of Stillbirth in a Nonhuman Primate Model of Excess Nutrition
Frias, A. E., Morgan, T. K., Evans, A. E., Rasanen, J., Oh, K. Y., Thornburg, K. L., & Grove, K. L. (2011) · Endocrinology · doi:10.1210/en.2010-1332 · Cited by 268 · see citing works
Approaching the shared biology of obesity and depression: the stress axis as the locus of gene–environment interactions
Bornstein, S. R., Schuppenies, A., Wong, M., & Licinio, J. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001873 · Cited by 267 · see citing works
Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice
Stenzel‐Poore, M. P., Cameron, V. A., Vaughan, J. M., Sawchenko, P. E., & Vale, W. (1992) · Endocrinology · doi:10.1210/endo.130.6.1597149 · Cited by 263 · see citing works
The psychobiology of comfort eating: implications for neuropharmacological interventions
Gibson, E. L. (2012) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e328357bd4e · Cited by 262 · see citing works
Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring
Tozuka, Y., Kumon, M., Wada, E., Onodera, M., Mochizuki, H., & Wada, K. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.05.015 · Cited by 260 · see citing works
Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
Wei, H., Chadman, K. K., McCloskey, D. P., Sheikh, A. M., Malik, M. N., Brown, W. T., & Li, X. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.01.011 · Cited by 257 · see citing works
Evidence that hypophagia induced bymCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors
Kennett, G. A., & Curzon, G. (1988) · Psychopharmacology · doi:10.1007/bf02431539 · Cited by 256 · see citing works
Nutrient Intake From Food in Children With Autism
Hyman, S. L., Stewart, P. A., Schmidt, B., Cain, U., Lemcke, N., Foley, J. T., Peck, R., Clemons, T., Reynolds, A., Johnson, C., et al. (2012) · Pediatrics · doi:10.1542/peds.2012-0900l · Cited by 255 · see citing works
Pregravid Obesity Associates With Increased Maternal Endotoxemia and Metabolic Inflammation
Basu, S., Haghiac, M., Surace, P., Challier, J.-C., Guerre-Millo, M., Singh, K., Waters, T. P., Minium, J., Presley, L. H., Catalano, P. M., et al. (2010) · Obesity · doi:10.1038/oby.2010.215 · Cited by 245 · see citing works
Psychosocial functioning in the obese before and after weight reduction: construct validity and responsiveness of the Obesity-related Problems scale
Karlsson, J., Taft, C., Sjöström, L., Torgerson, J., & Sullivan, M. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802272 · Cited by 238 · see citing works
Metabolic syndrome and mental illness.
Newcomer, J. W. (2007) · PubMed · Cited by 233 · see citing works
Maternal pre‐pregnancy obesity and risk for inattention and negative emotionality in children
Rodriguez, A. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2009.02133.x · Cited by 233 · see citing works
Risk of completed suicide after bariatric surgery: a systematic review
Peterhänsel, C., Petroff, D., Klinitzke, G., Kersting, A., & Wagner, B. (2013) · Obesity Reviews · doi:10.1111/obr.12014 · Cited by 229 · see citing works
Transcranial direct current stimulation (tDCS) in unipolar vs. bipolar depressive disorder
Brunoni, A. R., Ferrucci, R., Bortolomasi, M., Vergari, M., Tadini, L., Boggio, P. S., Giacopuzzi, M., Barbieri, S., & Priori, A. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.09.010 · Cited by 226 · see citing works
Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8
Ellman, L. M., Deicken, R. F., Vinogradov, S., Kremen, W. S., Poole, J. H., Kern, D. M., Tsai, W. Y., Schaefer, C. A., & Brown, A. S. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.05.014 · Cited by 225 · see citing works
Longitudinal Evidence for Unfavorable Effects of Antidepressants on Heart Rate Variability
Licht, C. M. M., de Geus, E. J. C., van Dyck, R., & Penninx, B. W. J. H. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.032 · Cited by 225 · see citing works
A possible role of neuropeptide Y in depression and stress
Morales‐Medina, J. C., Dumont, Y., & Quirion, R. (2009) · Brain Research · doi:10.1016/j.brainres.2009.09.077 · Cited by 217 · see citing works
Maternal high fat diet consumption during the perinatal period programs offspring behavior
Sullivan, E. L., Nousen, E. K., & Chamlou, K. A. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.07.014 · Cited by 217 · see citing works
Self-citation
Hyperphagia and Increased Growth in Rats After Intraventricular Injection of 5,7-Dihydroxytryptamine
Saller, C. F., & Stricker, E. M. (1976) · Science · doi:10.1126/science.1257774 · Cited by 214 · see citing works
Waist circumference, abdominal obesity, and depression among overweight and obese U.S. adults: national health and nutrition examination survey 2005-2006
Zhao, G., Ford, E. S., Li, C., Tsai, J., Dhingra, S., & Balluz, L. S. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-130 · Cited by 214 · see citing works
Cytokine hypothesis of schizophrenia pathogenesis: Evidence from human studies and animal models
Watanabe, Y., Someya, T., & Nawa, H. (2010) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2010.02094.x · Cited by 204 · see citing works
Prevalence of Obesity Among Children With Chronic Conditions
Chen, A. Y., Kim, S. E., Houtrow, A. J., & Newacheck, P. W. (2009) · Obesity · doi:10.1038/oby.2009.185 · Cited by 204 · see citing works
The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
Oades, R. D., Lasky-Su, J., Christiansen, H., Faraone, S. V., Sonuga-Barke, E. J. S., Banaschewski, T., Chen, W., Anney, R. J. L., Buitelaar, J. K., Ebstein, R. P., et al. (2008) · Behavioral and Brain Functions · doi:10.1186/1744-9081-4-48 · Cited by 200 · see citing works
Increased cerebrospinal fluid interleukin-6 levels in patients with schizophrenia and those with major depressive disorder
Sasayama, D., Hattori, K., Wakabayashi, C., Teraishi, T., Hori, H., Ota, M., Yoshida, S., Arima, K., Higuchi, T., Amano, N., et al. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.12.001 · Cited by 198 · see citing works
The role of BDNF in the pathophysiology and treatment of schizophrenia
Favalli, G. P. D. S., Li, J., Belmonte-de-Abreu, P. S., Wong, A. H. C., & Daskalakis, Z. J. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.09.022 · Cited by 197 · see citing works
Rates and risks for co-morbid depression in patients with Type 2 diabetes mellitus: results from a community-based study
Pouwer, F., Beekman, A. T. F., Nijpels, G., Dekker, J. M., Snoek, F. J., Kostense, P. J., Heine, R. J., & Deeg, D. J. H. (2003) · Diabetologia · doi:10.1007/s00125-003-1124-6 · Cited by 197 · see citing works
Biological Basis of Depression in Adults with Diabetes
Champaneri, S., Wand, G. S., Malhotra, S., Casagrande, S. S., & Golden, S. H. (2010) · Current Diabetes Reports · doi:10.1007/s11892-010-0148-9 · Cited by 196 · see citing works
Obesity‐related dysregulation of the Tryptophan–Kynurenine metabolism: Role of age and parameters of the metabolic syndrome
Mangge, H., Summers, K. L., Meinitzer, A., Zelzer, S., Almer, G., Prassl, R., Schnedl, W. J., Reininghaus, E. Z., Paulmichl, K., Weghuber, D., et al. (2013) · Obesity · doi:10.1002/oby.20491 · Cited by 186 · see citing works
Unadjusted and Adjusted Prevalence of Diagnosed Depression in Type 2 Diabetes
Nichols, G. A., & Brown, J. B. (2003) · Diabetes Care · doi:10.2337/diacare.26.3.744 · Cited by 185 · see citing works
Interactions between NPY and CRF in the amygdala to regulate emotionality
Sajdyk, T. J., Shekhar, A., & Gehlert, D. R. (2004) · Neuropeptides · doi:10.1016/j.npep.2004.05.006 · Cited by 183 · see citing works
Reduced Behavioral Effects of Cocaine in Heterozygous Brain-Derived Neurotrophic Factor (BDNF) Knockout Mice
Hall, F. S., Drgonová, J., Goeb, M., & Uhl, G. R. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300192 · Cited by 180 · see citing works
Association Between Adult Attention Deficit/Hyperactivity Disorder and Obesity in the US Population
Pagoto, S., Curtin, C., Lemon, S. C., Bandini, L. G., Schneider, K. L., Bodenlos, J. S., & Ma, Y. (2009) · Obesity · doi:10.1038/oby.2008.587 · Cited by 179 · see citing works
Perinatal Exposure to High-Fat Diet Programs Energy Balance, Metabolism and Behavior in Adulthood
Sullivan, E. L., Smith, M. S., & Grove, K. L. (2010) · Neuroendocrinology · doi:10.1159/000322038 · Cited by 178 · see citing works
Self-citation
Metabolic hormones, dopamine circuits, and feeding
Narayanan, N. S., Guarnieri, D. J., & Dileone, R. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.10.004 · Cited by 178 · see citing works
Metabolic Syndrome Predisposes to Depressive Symptoms
Koponen, H., Jokelainen, J. J., Keinanen-Kiukaanniemi, S. M., Kumpusalo, E. A., & Vanhala, M. J. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0202 · Cited by 177 · see citing works
Endocrine abnormalities of obesity
Björntorp, P. A. (1995) · Metabolism · doi:10.1016/0026-0495(95)90315-1 · Cited by 173 · see citing works
A Longitudinal Study of Childhood Depression and Anxiety in Relation to Weight Gain
Rofey, D. L., Kolko, R. P., Iosif, A., Silk, J. S., Bost, J. E., Feng, W., Szigethy, E., Noll, R. B., Ryan, N. D., & Dahl, R. E. (2009) · Child Psychiatry & Human Development · doi:10.1007/s10578-009-0141-1 · Cited by 170 · see citing works
Imaging of Brain Dopamine Pathways
Wang, G., Volkow, N. D., Thanos, P. K., & Fowler, J. S. (2009) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e31819a86f7 · Cited by 167 · see citing works
Neuroinflammation in autism spectrum disorders
El-Ansary, A. K., & AL-Ayadhi, L. Y. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-265 · Cited by 167 · see citing works
Maternal high-fat diet in mice programs emotional behavior in adulthood
Peleg-Raibstein, D., Luca, E., & Wolfrum, C. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.05.027 · Cited by 167 · see citing works
The longitudinal relation between chronic diseases and depression in older persons in the community: the Longitudinal Aging Study Amsterdam
Bisschop, M. I., Kriegsman, D. M. W., Deeg, D. J. H., Beekman, A. T. F., & van Tilburg, W. (2004) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2003.01.001 · Cited by 163 · see citing works
Distribution of serotonin 5‐HT1C receptor mRNA in adult rat brain
Hoffman, B. J., & Mezey, É. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)81390-0 · Cited by 160 · see citing works
Distribution and cellular localization of the serotonin type 2C receptor messenger RNA in human brain
Pasqualetti, M., Ori, M., Castagna, M., Marazziti, D., Cassano, G. B., & Nardi, I. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00011-1 · Cited by 154 · see citing works
Night eating syndrome: A critical review of the literature
Wal, J. S. V. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2011.11.001 · Cited by 148 · see citing works
Effect of anorexic drugs on food intake and the micro-structure of eating in human subjects
Rogers, P. J., & Blundell, J. E. (1979) · Psychopharmacology · doi:10.1007/bf00427624 · Cited by 148 · see citing works
5-HT1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively
Andrews, N., Hogg, S., Gonzalez, L. E., & File, S. E. (1994) · European Journal of Pharmacology · doi:10.1016/0014-2999(94)00473-0 · Cited by 148 · see citing works
Obesity and psychopathology in women: a three decade prospective study
Kasen, S., Cohen, P. R., Chen, H., & Must, A. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803736 · Cited by 147 · see citing works
Weight Gain and Other Metabolic Adverse Effects Associated with Atypical Antipsychotic Treatment of Children and Adolescents: A Systematic Review and Meta-analysis
Almandil, N. B., Liu, Y., Murray, M. L., Besag, F., Aitchison, K. J., & Wong, I. C. K. (2013) · Pediatric Drugs · doi:10.1007/s40272-013-0016-6 · Cited by 146 · see citing works
Chronic Disease Risks in Young Adults With Autism Spectrum Disorder: Forewarned Is Forearmed
Tyler, C. V., Schramm, S., Karafa, M., Tang, A., & Jain, A. (2011) · American Journal on Intellectual and Developmental Disabilities · doi:10.1352/1944-7558-116.5.371 · Cited by 145 · see citing works
Examining the relationship between Attention-Deficit/Hyperactivity Disorder and overweight in children and adolescents
Erhart, M., Herpertz‐Dahlmann, B., Wille, N., Sawitzky-Rose, B., Hölling, H., & Ravens‐Sieberer, U. (2011) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-011-0230-0 · Cited by 139 · see citing works
Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population
Hotta, K., Nakamura, M., Nakamura, T., Matsuo, T., Nakata, Y., Kamohara, S., Miyatake, N., Kotani, K., Komatsu, R., Itoh, N., et al. (2009) · Journal of Human Genetics · doi:10.1038/jhg.2009.106 · Cited by 135 · see citing works
Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype
McKernan, D. P., Dennison, U., Gaszner, G., Cryan, J. F., & Dinan, T. G. (2011) · Translational Psychiatry · doi:10.1038/tp.2011.37 · Cited by 131 · see citing works
Depression Severity, Diet Quality, and Physical Activity in Women with Obesity and Depression
Appelhans, B. M., Whited, M. C., Schneider, K. L., Ma, Y., Oleski, J. L., Merriam, P. A., Waring, M. E., Olendzki, B. C., Mann, D. M., Ockene, I. S., et al. (2012) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2012.02.006 · Cited by 131 · see citing works
Effects of antidepressants on glucose metabolism and diabetes mellitus type 2 in adults
Deuschle, M. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32835a4206 · Cited by 130 · see citing works
Metabolic Imprinting in Obesity
Sullivan, E. L., & Grove, K. L. (2009) · Forum of nutrition/Bibliotheca Nutritio et dieta · doi:10.1159/000264406 · Cited by 125 · see citing works
Self-citation
Impaired Executive Function Mediates the Association between Maternal Pre-Pregnancy Body Mass Index and Child ADHD Symptoms
Buß, C., Entringer, S., Davis, E. P., Hobel, C. J., Swanson, J. M., Wadhwa, P. D., & Sandman, C. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037758 · Cited by 125 · see citing works
Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress
Coste, S. C., Murray, S., & Stenzel‐Poore, M. P. (2001) · Peptides · doi:10.1016/s0196-9781(01)00386-2 · Cited by 117 · see citing works
Obesity in Men With Childhood ADHD: A 33-Year Controlled, Prospective, Follow-up Study
Cortese, S., Ramos-Olazagasti, M. A., Klein, R. G., Castellanos, F. X., Proal, E., & Mannuzza, S. (2013) · PEDIATRICS · doi:10.1542/peds.2012-0540 · Cited by 114 · see citing works
High Maternal Intake of Polyunsaturated Fatty Acids During Pregnancy in Mice Alters Offsprings’ Aggressive Behavior, Immobility in the Swim Test, Locomotor Activity and Brain Protein Kinase C Activity
Raygada, M. J., Cho, E., & Hilakivi‐Clarke, L. (1998) · Journal of Nutrition · doi:10.1093/jn/128.12.2505 · Cited by 113 · see citing works
Obesity and suicide risk in adults—A systematic review
Klinitzke, G., Steinig, J., Blüher, M., Kersting, A., & Wagner, B. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.07.010 · Cited by 112 · see citing works
Increased Serotonin and Dopamine Transporter Binding in Psychotropic Medication–Naïve Patients with Generalized Social Anxiety Disorder Shown by123I-β-(4-Iodophenyl)-Tropane SPECT
van der Wee, N. J., Veen, J. F. V., Stevens, H., van Vliet, I. M., van Rijk, P. P., & Westenberg, H. G. M. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.045518 · Cited by 107 · see citing works
Reduced neuropeptide Y mRNA levels in the frontal cortex of people with schizophrenia and bipolar disorder
Kuromitsu, J., Yokoi, A., Kawai, T., Nagasu, T., Aizawa, T., Haga, S., & Ikeda, K. (2001) · Gene Expression Patterns · doi:10.1016/s1567-133x(01)00003-5 · Cited by 101 · see citing works
Association of ADHD, tics, and anxiety with dopamine transporter ( DAT1 ) genotype in autism spectrum disorder
Gadow, K. D., Roohi, J., DeVincent, C. J., & Hatchwell, E. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01952.x · Cited by 100 · see citing works
Influence of escitalopram treatment on 5-HT1A receptor binding in limbic regions in patients with anxiety disorders
Spindelegger, C., Lanzenberger, R. R., Wadsak, W., Mien, L., Stein, P., Mitterhauser, M., Moser, U., Holik, A., Pezawas, L., Kletter, K., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.35 · Cited by 100 · see citing works
Metabolic syndrome and short‐term heart rate variability in young adults
Koskinen, T., Kähönen, M. A. P., Jula, A., Mattsson, N., Laitinen, T. P., Keltikangas‐Järvinen, L., Viikari, J., Välimäki, I., Rönnemaa, T., & Raitakari, O. T. (2009) · Diabetic Medicine · doi:10.1111/j.1464-5491.2009.02686.x · Cited by 97 · see citing works
Low Cerebrospinal Fluid Transthyretin Levels in Depression: Correlations with Suicidal Ideation and Low Serotonin Function
Sullivan, G. M., Mann, J. J., Oquendo, M. A., LO, E. S., Cooper, T. B., & Gorman, J. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.11.022 · Cited by 95 · see citing works
Night eating syndrome: implications for severe obesity
Cleator, J., Abbott, J., Judd, P. A., Sutton, C., & Wilding, J. P. H. (2012) · Nutrition and Diabetes · doi:10.1038/nutd.2012.16 · Cited by 94 · see citing works
Weight Gain and Glucose Dysregulation with Second-Generation Antipsychotics and Antidepressants: A Review for Primary Care Physicians
Hasnain, M., Vieweg, W. V. R., & Hollett, B. (2012) · Postgraduate Medicine · doi:10.3810/pgm.2012.07.2577 · Cited by 93 · see citing works
Does Diabetes Double the Risk of Depression?
O'Connor, P., Crain, A., Rush, W., Hanson, A., Fischer, L., & Kluznik, J. (2009) · Annals of Family Medicine · doi:10.1370/afm.964 · Cited by 93 · see citing works
Maternal Health in Pregnancy and Intellectual Disability in the Offspring: A Population-Based Study
Leonard, H., de Klerk, N. H., Bourke, J., & Bower, C. I. (2005) · Annals of Epidemiology · doi:10.1016/j.annepidem.2005.05.002 · Cited by 92 · see citing works
The 5-HT1B Receptor Agonist CP-94,253 Reduces Food Intake and Preserves the Behavioural Satiety Sequence
Halford, J. C. G., & Blundell, J. E. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(96)00073-x · Cited by 91 · see citing works
CP-94,253: a selective serotonin 1B (5-HT 1B ) agonist that promotes satiety
Lee, M. D., & Simansky, K. J. (1997) · Psychopharmacology · doi:10.1007/s002130050292 · Cited by 91 · see citing works
Reduction in Psychopathology following Bariatric Surgery for Morbid Obesity
Maddi, S. R., Fox, S. R., Harvey, R. H., Lu, J. L., Khoshaba, D. M., & Persico, M. (2001) · Obesity Surgery · doi:10.1381/09608920160558605 · Cited by 89 · see citing works
The effect of 5-hydroxytryptophan on food intake and on the anorexic action of amphetamine and fenfluramine
Blundell, J. E., & Leshem, M. (1975) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1975.tb09374.x · Cited by 88 · see citing works
Central action of anorexic agents: Effects of amphetamine and fenfluramine in rats with lateral hypothalamic lesions
Blundell, J. E., & Leshem, M. (1974) · European Journal of Pharmacology · doi:10.1016/0014-2999(74)90115-0 · Cited by 86 · see citing works
Reduced neuropeptide Y mRNA expression in the prefrontal cortex of subjects with bipolar disorder
Caberlotto, L., & Hurd, Y. L. (1999) · Neuroreport · doi:10.1097/00001756-199906030-00022 · Cited by 86 · see citing works
Short-term consumption of a diet rich in fat decreases anxiety response in adult male rats
Prasad, A., & Prasad, C. V. S. R. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(96)00135-7 · Cited by 86 · see citing works
Lifelong Enhanced Diabetes Susceptibility and Obesity after Temporary Intrahypothalamic Hyperinsulinism during Brain Organization
Plagemann, A., Heidrich, I., Götz, F., Rohde, W., & Dörner, G. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1211143 · Cited by 85 · see citing works
THE SERTRALINE VERSUS ELECTRICAL CURRENT THERAPY FOR TREATING DEPRESSION CLINICAL STUDY (SELECT-TDCS): RESULTS OF THE CROSSOVER AND FOLLOW-UP PHASES
Valiengo, L. D. C. L., Benseñor, I. M., Goulart, A. C., de Oliveira, J. F., Zanao, T. A., Boggio, P. S., Lotufo, P. A., Fregni, F., & Brunoni, A. R. (2013) · Depression and Anxiety · doi:10.1002/da.22079 · Cited by 85 · see citing works
Is ignorance bliss? Depression, antidepressants, and the diagnosis of prediabetes and type 2 diabetes.
Mezuk, B. R., Johnson‐Lawrence, V., Lee, H. E., Rafferty, J. A., Abdou, C. M., Uzogara, E. E., & Jackson, J. S. (2013) · Health Psychology · doi:10.1037/a0029014 · Cited by 83 · see citing works
The relationship between body mass index and mental health
McLaren, L., Beck, C. A., Patten, S. B., Fick, G. H., & Adair, C. E. (2007) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-007-0269-x · Cited by 82 · see citing works
Temporal Relationships Between Overweight and Obesity andDSM-IVSubstance Use, Mood, and Anxiety Disorders
Pickering, R. P., Goldstein, R. B., Hasin, D. S., Blanco, C., Smith, S. M. R., Huang, B., Pulay, A. J., Ruan, W. J., Saha, T. D., Stinson, F. S., et al. (2011) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.10m06077gry · Cited by 81 · see citing works
A proposed mechanism for autism: an aberrant neuroimmune response manifested as a psychiatric disorder
Buehler, M. R. (2011) · Medical Hypotheses · doi:10.1016/j.mehy.2011.02.038 · Cited by 81 · see citing works
Metabolic syndrome, physical activity and cardiac autonomic function
Soares‐Miranda, L., SANDERCOCK, G. R. H., Vale, S. M. C. G., Santos, R., Abreu, S., Moreira, C. M. M., & Mota, J. A. P. S. (2012) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2281 · Cited by 80 · see citing works
Short-term heart rate variability in healthy young adults
Koskinen, T., Kähönen, M. A. P., Jula, A., Laitinen, T. P., Keltikangas‐Järvinen, L., Viikari, J. S. A., Välimäki, I. A. T., & Raitakari, O. T. (2008) · Autonomic Neuroscience · doi:10.1016/j.autneu.2008.10.011 · Cited by 79 · see citing works
Perinatal inflammatory cytokine challenge results in distinct neurobehavioral alterations in rats: implication in psychiatric disorders of developmental origin
Tohmi, M., Tsuda, N., Watanabe, Y., Kakita, A., & Nawa, H. (2004) · Neuroscience Research · doi:10.1016/j.neures.2004.05.010 · Cited by 78 · see citing works
Hypothalamic substrates of metabolic imprinting
Simerly, R. B. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.023 · Cited by 76 · see citing works
Effects of d-amphetamine and fenfluramine on feeding patterns and activity of obese and lean Zucker rats
Grinker, J. A., Drewnowski, A., Enns, M. P., & Kissileff, H. R. (1980) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(80)90367-6 · Cited by 76 · see citing works
Symptoms of attention deficit hyperactivity disorder in severely obese women
Fleming, J. P., Levy, L. D., & Levitan, R. D. (2005) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/bf03354661 · Cited by 75 · see citing works
Metabolic Syndrome and Short-Term and Long-Term Heart Rate Variability in Elderly Free of Clinical Cardiovascular Disease: The PROOF Study
Assoumou, H.-G. N., Pichot, V., Barthélemy, J., Dauphinot, V., Celle, S., Gosse, P., Kossovsky, M. P., Gaspoz, J., & Roche, F. (2010) · Rejuvenation Research · doi:10.1089/rej.2010.1019 · Cited by 75 · see citing works
Brief report: The dopamine-3-receptor gene (DRD3) is associated with specific repetitive behavior in Autism Spectrum Disorder (ASD)
Staal, W. G., de Krom, M., & de Jonge, M. V. (2012) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-011-1312-z · Cited by 75 · see citing works
Psychosocial Correlates of Psychopathology in a National Sample of the Morbidly Obese
Maddi, S. R., Khoshaba, D. M., Persico, M., Bleecker, F., & VanArsdall, G. (1997) · Obesity Surgery · doi:10.1381/096089297765555377 · Cited by 73 · see citing works
Psychological Outcomes and Predictors of Initial Weight Loss Outcomes Among Severely Obese Adolescents Receiving Laparoscopic Adjustable Gastric Banding
Sysko, R., Devlin, M. J., Hildebrandt, T., Brewer, S. K., Zitsman, J. L., & Walsh, B. T. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12m07690 · Cited by 72 · see citing works
The Impact of the Components of Metabolic Syndrome on Heart Rate Variability: Using the NCEP‐ATP III and IDF Definitions
Min, K., Min, J., Paek, D., & Cho, S. (2008) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2008.01045.x · Cited by 72 · see citing works
Association of the BDNF Val66Met variation with obesity in women
Beckers, S., Peeters, A. V., Zegers, D., Mertens, I. L., Gaal, L. V., & Hul, W. V. (2008) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2008.06.008 · Cited by 72 · see citing works
Neurobehavioural deficits associated with apoptotic neurodegeneration and vulnerability for ADHD
Fredriksson, A., & Archer, T. (2004) · Neurotoxicity Research · doi:10.1007/bf03033280 · Cited by 71 · see citing works
Maternal hormonal manipulations in rats cause obesity and increase medial hypothalamic norepinephrine release in male offspring
Jones, A. P., Pothos, E. N., Rada, P. V., Olster, D. H., & Hoebel, B. G. (1995) · Developmental Brain Research · doi:10.1016/0165-3806(95)00078-r · Cited by 70 · see citing works
Pre-pregnancy maternal overweight and obesity increase the risk for affective disorders in offspring
Robinson, M., Zubrick, S. R., Pennell, C. E., Lieshout, R. J. V., Jacoby, P. A., Beilin, L. J., Mori, T. A., Stanley, F., Newnham, J. P., & Oddy, W. H. (2012) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174412000578 · Cited by 70 · see citing works
Modifiable risk factors for schizophrenia and autism — Shared risk factors impacting on brain development
Hamlyn, J., Duhig, M., McGrath, J. J., & Scott, J. G. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.10.023 · Cited by 68 · see citing works
The frequency and clinical significance of intra-amniotic infection and/or inflammation in women with placenta previa and vaginal bleeding: an unexpected observation
Madan, I., Romero, R. J., Kusanovic, J. P., Mittal, P., Chaiworapongsa, T., Dong, Z., Mazaki‐Tovi, S., Vaisbuch, E., Savasan, Z. A., Yeo, L., et al. (2010) · Journal of Perinatal Medicine · doi:10.1515/jpm.2010.001 · Cited by 67 · see citing works
Night eating syndrome: an overview
Milano, W., Rosa, M. D., Milano, L., & Capasso, A. (2011) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.2011.01353.x · Cited by 66 · see citing works
Higher dopamine transporter density in Parkinson’s disease patients with depression
Felicio, A. C., Moriyama, T. S., Godeiro-Junior, C. D. O., Shih, M. C., Hoexter, M. Q., Borges, V., Silva, S. M. A., Amaro, E., de Andrade, L. A. F., Ferraz, H. B., et al. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1867-y · Cited by 65 · see citing works
Neurobiology of Nutrition and Obesity
Morrison, C. D., & Berthoud, H. (2007) · Nutrition Reviews · doi:10.1301/nr.2007.dec.517-534 · Cited by 65 · see citing works
Changes in dopamine D2-receptor binding are associated to symptom reduction after psychotherapy in social anxiety disorder
Červenka, S., Hedman‐Lagerlöf, E., Ikoma, Y., Djurfeldt, D. R., Rück, C., Halldin, C., & Lindefors, N. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.40 · Cited by 64 · see citing works
Pre- and Postoperative Psychological Characteristics in Morbidly Obese Patients
Papageorgiou, G. M., Papakonstantinou, A., Mamplekou, E., Terzis, I., & Melissas, J. (2002) · Obesity Surgery · doi:10.1381/096089202762252307 · Cited by 62 · see citing works
The Efficacy of Pramipexole, a Dopamine Receptor Agonist, as an Adjunctive Treatment in Treatment-Resistant Depression: An Open-Label Trial
Hori, H., & Kunugi, H. (2012) · The Scientific World Journal · doi:10.1100/2012/372474 · Cited by 62 · see citing works
Changes in the cardiac autonomic regulation in children with attention deficit hyperactivity disorder (ADHD).
Tonhajzerová, I., Ondrejka, I., Adamík, P., Hrubý, R., Javorka, M., Trunkvalterova, Z., Mokrá, D., & Javorka, K. (2009) · PubMed · Cited by 59 · see citing works
Increased interleukin-6 and tumor necrosis factor alpha in first episode schizophrenia patients versus healthy controls.
Kubistova, A., Horáček, J., & Novák, T. (2012) · PubMed · Cited by 59 · see citing works
Serial Measurement of Uterine Blood Flow From Mid to Late Gestation in Growth Restricted Pregnancies Induced by Overnourishing Adolescent Sheep Dams
Wallace, J. M., Milne, J. S., MATSUZAKI, M., & Aitken, R. P. (2008) · Placenta · doi:10.1016/j.placenta.2008.05.006 · Cited by 57 · see citing works
Effects of BDNF, T3, and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro
Byerly, M. S., Simon, J., Bihan-Duval, É. L., Duclos, M. J. M. J., Cogburn, L. A., & Porter, T. E. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90813.2008 · Cited by 57 · see citing works
Control of hyperphagia prevents obesity in BDNF heterozygous mice
Coppola, V., & Tessarollo, L. (2004) · Neuroreport · doi:10.1097/00001756-200412030-00022 · Cited by 56 · see citing works
Amphetamine induced dopamine release increases anxiety in individuals recovered from anorexia nervosa
Bailer, U., Narendran, R., Frankle, W., Himes, M. L., Duvvuri, V., Mathis, C., & Kaye, W. (2011) · International Journal of Eating Disorders · doi:10.1002/eat.20937 · Cited by 54 · see citing works
NPY Y1 receptors in the dorsal periaqueductal gray matter regulate anxiety in the social interaction test
Kask, A., Rägo, L., & Harro, J. (1998) · Neuroreport · doi:10.1097/00001756-199808240-00005 · Cited by 54 · see citing works
Inflammation: good or bad for ADHD?
Donev, R., & Thome, J. (2010) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-010-0038-7 · Cited by 54 · see citing works
Molecular epidemiology of major depressive disorder
Kiyohara, C., & Yoshimasu, K. (2009) · Environmental Health and Preventive Medicine · doi:10.1007/s12199-008-0073-6 · Cited by 53 · see citing works
Antidepressant Use Before and After the Diagnosis of Type 2 Diabetes
Mika Kivimaki, B., Tabák, Á. G., Lawlor, D. A., Batty, G. D., Singh‐Manoux, A., Jokela, M. M., Virtanen, M., Salo, P., Oksanen, T., Pentti, J., et al. (2010) · Diabetes Care · doi:10.2337/dc09-2359 · Cited by 52 · see citing works
Functional Genomics of Attention-Deficit/Hyperactivity Disorder (ADHD) Risk Alleles on Dopamine Transporter Binding in ADHD and Healthy Control Subjects
Spencer, T. J., Biederman, J., Faraone, S. V., Madras, B. K., Bonab, A. A., Dougherty, D. D., Batchelder, H., Clarke, A., & Fischman, A. J. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.11.010 · Cited by 51 · see citing works
Mothers of Children Diagnosed With Attention-Deficit/Hyperactivity Disorder
Ray, G. T., Croen, L., & Habel, L. A. (2008) · Medical Care · doi:10.1097/mlr.0b013e31817e18c0 · Cited by 51 · see citing works
Diabetes mellitus type II as a risk factor for depression: a lower than expected risk in a general practice setting
Aarts, S., van den Akker, M., van Boxtel, M. P. J., Jolles, J., Winkens, B., & Metsemakers, J. F. M. (2009) · European Journal of Epidemiology · doi:10.1007/s10654-009-9385-0 · Cited by 49 · see citing works
Screening of Adult ADHD Among Patients Presenting for Bariatric Surgery
Alfonsson, S., Parling, T., & Ghaderi, A. (2011) · Obesity Surgery · doi:10.1007/s11695-011-0569-9 · Cited by 48 · see citing works
Association of depression and its relation with complications in newly diagnosed type 2 diabetes
Bajaj, S., Agarwal, S., Varma, A., & Singh, V. (2012) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.100670 · Cited by 48 · see citing works

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Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta‐analysis
Vancampfort, D., Stubbs, B., Mitchell, A. J., De Hert, M., Wampers, M., Ward, P. B., Rosenbaum, S., & Correll, C. U. (2015) · World Psychiatry · doi:10.1002/wps.20252 · Cited by 1,271 · see citing works
Microemulsion utility in pharmaceuticals: Implications for multi-drug delivery
Callender, S. P., Mathews, J. A., Kobernyk, K., & Wettig, S. D. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.05.005 · Cited by 399 · see citing works
Development of prefrontal cortex
Kolk, S. M., & Rakic, P. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01137-9 · Cited by 378 · see citing works
Towards a multidisciplinary approach to understand and manage obesity and related diseases
Bischoff, S. C., Boirie‌, Y., Cederholm, T., Chourdakis, M., Cuerda, C., Delzenne, N. M., Deutz, N. E. P., Fouque, D. P., Genton, L., Gil, C., et al. (2016) · Clinical Nutrition · doi:10.1016/j.clnu.2016.11.007 · Cited by 211 · see citing works
Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer’s disease
Busquets, O., Ettcheto, M., Pallàs, M., Beas‐Zárate, C., Verdaguer, E., Auladell, C., Folch, J., & Camins, A. (2016) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2016.11.002 · Cited by 104 · see citing works
Hypertension risk and clinical care in patients with bipolar disorder or schizophrenia; a systematic review and meta-analysis
Ayerbe, L., Forgnone, I., Addo, J., Siguero, A., Gelati, S., & Ayis, S. A. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.09.002 · Cited by 100 · see citing works
Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review
Kong, L., Chen, X., Gissler, M., & Lavebratt, C. (2020) · International Journal of Obesity · doi:10.1038/s41366-020-0609-4 · Cited by 100 · see citing works
Serum triglycerides, but not cholesterol or leptin, are decreased in suicide attempters with mood disorders
Cantarelli, M. D. G., Nardin, P., Buffon, A., Eidt, M. C., Godoy, L. A., Fernandes, B. S., & Gonçalves, C. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.10.033 · Cited by 87 · see citing works
The psychobiological links between chronic stress‐related diseases, periodontal/peri‐implant diseases, and wound healing
Decker, A. M., Kapila, Y. L., & Wang, H. (2021) · Periodontology 2000 · doi:10.1111/prd.12381 · Cited by 83 · see citing works
The potential association between obesity and bipolar disorder: A meta-analysis
Zhao, Z., Okusaga, O. O., Quevedo, J., Soares, J. C., & Teixeira, A. L. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.059 · Cited by 81 · see citing works
Exposure to chronic early-life stress lastingly alters the adipose tissue, the leptin system and changes the vulnerability to western-style diet later in life in mice
Yam, K. Y., Naninck, E. F. G., Abbink, M. R., la Fleur, S. E., Schipper, L., van den Beukel, J. C., Grefhorst, A., Oosting, A., van der Beek, E. M., Lucassen, P. J., et al. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.12.012 · Cited by 78 · see citing works
Disentangling Genetic Risks for Metabolic Syndrome
van Walree, E. S., Jansen, I. E., Bell, N. Y., Savage, J. E., de Leeuw, C., Nieuwdorp, M., van der Sluis, S., & Posthuma, D. (2022) · Diabetes · doi:10.2337/db22-0478 · Cited by 72 · see citing works
Therapeutic potential of glutathione-enhancers in stress-related psychopathologies
Zalachoras, I., Hollis, F., Ramos‐Fernández, E., Trovò, L., Sonnay, S., Geiser, E., Preitner, N., Steiner, P., Sandi, C., & Morató, L. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.03.015 · Cited by 67 · see citing works
Association of obesity with cognitive function and brain structure in patients with major depressive disorder
Hidese, S., Ota, M., Matsuo, J., Ishida, I., Hiraishi, M., Yoshida, S., Noda, T., Sato, N., Teraishi, T., Hattori, K., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.08.028 · Cited by 62 · see citing works
Signs of ongoing inflammation in female patients with chronic widespread pain
Gerdle, B. U. C., Ghafouri, B., Ghafouri, N., Bäckryd, E., & Gordh, T. (2017) · Medicine · doi:10.1097/md.0000000000006130 · Cited by 53 · see citing works
Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan
de Lombares, C., Heude, E., Alfama, G., Fontaine, A., Hassouna, R., Vernochet, C., de Chaumont, F., Olivo-Marin, C., Ey, E., Parnaudeau, S., et al. (2019) · Aging · doi:10.18632/aging.102141 · Cited by 52 · see citing works
Obesity and anxiety during pregnancy and postpartum: A systematic review
Nagl, M., Linde, K., Stepan, H., & Kersting, A. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.06.054 · Cited by 49 · see citing works
The Impact of GLP-1 Receptor Agonists (GLP-1 RAs) on Mental Health: A Systematic Review
Valenta, S. T., Nicastri, A., Perazza, F., Marcolini, F., Beghelli, V., Atti, A. R., & Petroni, M. L. (2024) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-024-00331-y · Cited by 47 · see citing works
Association between maternal serious mental illness and adverse birth outcomes
Heun‐Johnson, H., Seabury, S. A., Menchine, M. D., Claudius, I. A., Axeen, S., & Lakshmanan, A. (2019) · Journal of Perinatology · doi:10.1038/s41372-019-0346-5 · Cited by 46 · see citing works
Early experiences: Building up the tools to face the challenges of adult life
Branchi, I., & Cirulli, F. (2014) · Developmental Psychobiology · doi:10.1002/dev.21235 · Cited by 40 · see citing works
Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue
Ray, B., Sokol, D. K., Maloney, B., & Lahiri, D. K. (2016) · Scientific Reports · doi:10.1038/srep26052 · Cited by 42 · see citing works
Role of Stress, Depression, and Aging in Cognitive Decline and Alzheimer’s Disease
Daulatzai, M. A. (2014) · Current topics in behavioral neurosciences · doi:10.1007/7854_2014_350 · Cited by 42 · see citing works
Allostatic load and systemic comorbidities in psychiatric disorders
Finlay, S., Rudd, D., McDERMOTT, B. M., & Sarnyai, Z. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105726 · Cited by 41 · see citing works
Review article. Predicting disease onset in clinically healthy people
Zeliger, H. I. (2016) · Interdisciplinary Toxicology · doi:10.1515/intox-2016-0006 · Cited by 36 · see citing works
Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases
Cha, H. K., Chung, S., Lim, H. Y., Jung, J., & Son, G. H. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00496 · Cited by 36 · see citing works
Association of metabolic syndrome and its components with the risk of depressive symptoms: A systematic review and meta-analysis of cohort studies
Kim, H.-B., Wolf, B. J., & Kim, J. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.11.049 · Cited by 36 · see citing works
Immunomodulatory effects of antipsychotic treatment on gene expression in first-episode psychosis
Mantere, O., Trontti, K., García‐González, J., Balcells, I., Saarnio, S., Mäntylä, T. J. S., Lindgren, M., Kieseppä, T., Raij, T. T., Honkanen, J. K., et al. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.11.008 · Cited by 31 · see citing works
Impact of green space and built environment on metabolic syndrome: A systematic review with meta-analysis
Patwary, M. M., Sakhvidi, M. J. Z., Ashraf, S., Dadvand, P., Browning, M. H. E. M., Alam, M. A., Bell, M. L., James, P., & Astell‐Burt, T. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170977 · Cited by 30 · see citing works
Vitamin D deficiency exacerbates atypical antipsychotic-induced metabolic side effects in rats: Involvement of the INSIG/SREBP pathway
Dang, R., Jiang, P., Cai, H., Huan-de, L., Guo, R., Wu, Y., Zhang, L., Zhu, W.-Y., He, X., Liu, Y., et al. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.04.028 · Cited by 30 · see citing works
Paediatric obesity and metabolic syndrome associations with cognition and the brain in youth: Current evidence and future directions
Sadler, J. R., Thapaliya, G., Ranganath, K., Gabay, A., Chen, L., Smith, K., Osorio, R. S., Convit, A. J., & Carnell, S. (2023) · Pediatric Obesity · doi:10.1111/ijpo.13042 · Cited by 29 · see citing works
The Co-occurrence of Pediatric Obesity and ADHD: an Understanding of Shared Pathophysiology and Implications for Collaborative Management
O’Hara, V. M., Curran, J. L., & Browne, N. T. (2020) · Current Obesity Reports · doi:10.1007/s13679-020-00410-0 · Cited by 29 · see citing works
The association between insulin resistance, metabolic variables, and depressive symptoms in Mexican‐American elderly: A population‐based study
Diniz, B. S., Fisher‐Hoch, S. P., & McCormick, J. B. (2017) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4792 · Cited by 29 · see citing works
High Fructose Corn Syrup-Moderate Fat Diet Potentiates Anxio-Depressive Behavior and Alters Ventral Striatal Neuronal Signaling
Chakraborti, A., Graham, C., Chehade, S. B., Vashi, B., Umfress, A., Kurup, P. K., Vickers, B. N., Chen, H. A., Telange, R., Berryhill, T. F., et al. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.669410 · Cited by 26 · see citing works
GLP-1 Receptor Agonists in Mood Disorders: A Psychiatric Perspective
Carmellini, P., Cuomo, A., Rescalli, M. B., & Fagiolini, A. M. (2025) · Life · doi:10.3390/life15091422 · Cited by 25 · see citing works
Gut Microbiota and a Selectively Bred Taste Phenotype: A Novel Model of Microbiome-Behavior Relationships
Lyte, M., Fodor, A. A., Chapman, C. D., Martin, G. G., Peréz-Chanona, E., Jobin, C., & Dess, N. K. (2016) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000318 · Cited by 25 · see citing works
Hoarding disorder is associated with self-reported cardiovascular / metabolic dysfunction, chronic pain, and sleep apnea
Nutley, S. K., Camacho, M. R., Eichenbaum, J., Nosheny, R. L., Weiner, M. W., Delucchi, K., Mackin, R. S., & Mathews, C. A. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.12.032 · Cited by 24 · see citing works
The Association Between Metabolic Syndrome, Obesity-Related Outcomes, and ADHD in Adults With Comorbid Affective Disorders
Wynchank, D., Bijlenga, D., Lamers, F., Kooij, J. J. S., Bron, T. I., Beekman, A. T. F., & Penninx, B. W. J. H. (2016) · Journal of Attention Disorders · doi:10.1177/1087054716659137 · Cited by 22 · see citing works
Increased atherogenicity in mood disorders: a systematic review, meta-analysis and meta-regression
Jirakran, K., Almulla, A. F., Jaipinta, T., Vasupanrajit, A., Jansem, P., Tunvirachaisakul, C., Dzhambazova, E., Stoyanov, D., & Maes, M. H. J. (2025) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2025.106005 · Cited by 23 · see citing works
Hypertension and psychosis
Sudarshan, Y., & Cheung, B. M. Y. (2022) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2021-141386 · Cited by 20 · see citing works
High expression of hippocampal glutamic acid decarboxylase 67 mediates hypersensitivity of the hypothalamic-pituitary-adrenal axis in response to prenatal caffeine exposure in rats
Xu, D., Zhang, C., He, X., Guo, Z., Hu, D., Lu, J., Cheng, S., & Wang, H. (2017) · Toxicology Letters · doi:10.1016/j.toxlet.2017.10.019 · Cited by 19 · see citing works
Cardiovascular Risk in Early Psychosis: Relationship with Inflammation and Clinical Features 6 Months after Diagnosis
Barcones, M. F., MacDowell, K. S., García‐Bueno, B., Bioque, M., Gutiérrez-Galve, L., González-Pinto, A. M., Parellada, M., Bobes, J., Bernardo, M., Lobo, A., et al. (2017) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyx110 · Cited by 19 · see citing works
Chronic Psychosocial Stress Impairs Bone Homeostasis: A Study in the Social Isolation Reared Rat
Schiavone, S., Morgese, M. G., Mhillaj, E., Bové, M., Giorgi, A. D., Cantatore, F. P., Camerino, C., Tucci, P., Maffulli, N., Cuomo, V., et al. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00152 · Cited by 19 · see citing works
Prediction of Future Health Care Utilization Through Note-extracted Psychosocial Factors
Dorr, D. A., Quiñones, A. R., King, T., Wei, M. Y., White, K., & Bejan, C. A. (2022) · Medical Care · doi:10.1097/mlr.0000000000001742 · Cited by 18 · see citing works
Prevalence of metabolic syndrome and its associated risk factors in an African-Caribbean population with severe mental illness.
de Caluwé, L., van Buitenen, N., Gelan, P., Crunelle, C., Thomas, R., Casseres, S., Matthys, F., Harten, P., & Cahn, W. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.112558 · Cited by 15 · see citing works
Effects of treadmill exercise on cognitive functions and anxiety-related behaviors in ovariectomized diabetic rats
Mohammadi, M., & Zare, Z. (2020) · Physiology & Behavior · doi:10.1016/j.physbeh.2020.113021 · Cited by 17 · see citing works
Do genetic risk scores for body mass index predict risk of phobic anxiety? Evidence for a shared genetic risk factor
Walter, S., Glymour, M. M., Koenen, K. C., Liang, L., Tchetgen, E. J. T., Cornelis, M. C., Chang, S., Rewak, M., Rimm, E. B., Kawachi, I. I., et al. (2014) · Psychological Medicine · doi:10.1017/s0033291714001226 · Cited by 14 · see citing works
Depressive symptoms and risk of liver-related mortality in individuals with hepatitis B virus infection: a cohort study
Cho, I. Y., Chang, Y., Sung, E., Sohn, W., Kang, J., Shin, H. C., & Ryu, S. (2020) · Scientific Reports · doi:10.1038/s41598-020-77886-2 · Cited by 15 · see citing works
COVID-19 Associated Suicidal Ideation in Older Adults: Two Case Reports With a Review of the Literature
Asthana, N., Mehaffey, E., & Sewell, D. D. (2021) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2021.05.026 · Cited by 15 · see citing works
Striatal dopamine gene network moderates the effect of early adversity on the risk for adult psychiatric and cardiometabolic comorbidity
Barth, B., Arcego, D. M., Filho, E. J. D. M., de Lima, R. M. S., Parent, C. I., Dalmaz, C., Portella, A. K., Pokhvisneva, I., Meaney, M. J., & Silveira, P. P. (2024) · Scientific Reports · doi:10.1038/s41598-024-78465-5 · Cited by 14 · see citing works
Gender differences in metabolic syndrome risk factors among patients with serious mental illness
Tzeng, W., Chiang, Y., Feng, H., Chien, W., Tai, Y., & Chen, M. (2019) · International Journal of Mental Health Nursing · doi:10.1111/inm.12670 · Cited by 14 · see citing works
Common and specific aspects of anxiety and depression and the metabolic syndrome
Hoffmann, M. S., Brunoni, A. R., Stringaris, A. K., Viana, M. C., Lotufo, P. A., Benseñor, I. M., & Salum, G. A. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.02.052 · Cited by 14 · see citing works
Prevalence of cognitive impairment and associated factors in older people
Campos, A. C. B. F., Teixeira, I. G., Moraes, N. D. S., Cadorin, I. D. J., Morelli, P. M., Lídio, A. V., Medeiros, E. B., Garcez, M. L., Keller, G. S., Kucharska, E., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.03.072 · Cited by 13 · see citing works
Understanding the hidden epidemic of metabolic syndrome in people accessing community rehabilitation: a cross-sectional study of physical activity, dietary intake, and health literacy
Peiris, C. L., Harding, K. E., Porter, J. A., Shields, N., Gilfillan, C. P., & Taylor, N. F. (2022) · Disability and Rehabilitation · doi:10.1080/09638288.2022.2065540 · Cited by 14 · see citing works
Clinical Management of Obesity in Women
Ahmad, N. N., Butsch, W. S., & Aidarous, S. (2016) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/j.ogc.2016.01.007 · Cited by 11 · see citing works
Co-morditities of environmental diseases: A common cause
Zeliger, H. I. (2014) · Interdisciplinary Toxicology · doi:10.2478/intox-2014-0016 · Cited by 12 · see citing works
The endocannabinoidome–gut microbiome–brain axis as a novel therapeutic target for autism spectrum disorder
Campanale, A., Siniscalco, D., & Marzo, V. D. (2025) · Journal of Biomedical Science · doi:10.1186/s12929-025-01145-7 · Cited by 11 · see citing works
Uncoupling Protein-1 Modulates Anxiety-Like Behavior in a Temperature-Dependent Manner
Sideromenos, S., Gundacker, A., Nikou, M., Oberle, R., Horváth, O., Stöhrmann, P., Partonen, T., & Pollak, D. D. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.2509-21.2022 · Cited by 10 · see citing works
The Impact of Abnormal Glucose Tolerance and Obesity on Fetal Growth
Graves, E., Hill, D. J., Evers, S. E., Aarsen, K. V., Yama, B. A., Yuan, S., & Campbell, M. K. (2015) · Journal of Diabetes Research · doi:10.1155/2015/847674 · Cited by 10 · see citing works
Are overweight people more susceptible to anxiety?
Zhang, C., Li, M., Zhao, H., Zhu, R., Zheng, X., Lü, J., Du, Y., Yu, L., & Yang, T. (2018) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5050 · Cited by 10 · see citing works
NOS1AP Gene Variants and Their Role in Metabolic Syndrome: A Study of Patients with Schizophrenia
Mednova, I. A., Pozhidaev, I. V., Владимирович, Т. В., Бочарова, А. В., Paderina, D. Z., Boiko, A. S., Fedorenko, O. Y., Kornetova, E. G., Bokhan, N. A., Степанов, В. А., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12030627 · Cited by 9 · see citing works
Metabolic psychiatry targeting metabolic dysregulation in mental health
Sethi, S., Berk, M., Andreazza, A. C., Mujica-Parodi, L. R., Campbell, I. H., Campbell, H., Longhitano, C., Rasgon, N., Volek, J. S., Calkin, C. V., et al. (2026) · Nature Mental Health · doi:10.1038/s44220-026-00609-5 · Cited by 9 · see citing works
The 24-hour cognitive-affective physical behavior model: a theoretical framework for studying determinants and health consequences of physical activity, sedentary behavior, and sleep
Giurgiu, M., & Ebner‐Priemer, U. (2025) · Journal of Activity Sedentary and Sleep Behaviors · doi:10.1186/s44167-025-00077-9 · Cited by 9 · see citing works
The metabolic syndrome and risk of coronary artery disease in patients with chronic schizophrenia or schizoaffective disorder in a chronic mental institute
Tseng, P., Wang, H., Cheng, Y., Shen, F., Lin, P., & Wu, C.-K. (2014) · The Kaohsiung Journal of Medical Sciences · doi:10.1016/j.kjms.2014.09.002 · Cited by 8 · see citing works
The Depressed Heart
Perry, S. W., Licinio, J., & Wong, M. (2019) · Heart and Mind · doi:10.4103/hm.hm_13_19 · Cited by 8 · see citing works
Prevalence of the metabolic syndrome and associated factors among inpatients with severe mental illness in Botswana: a cross-sectional study
Tsima, B. M., Opondo, P. R., Mosepele, M., Mautle, E., Bilker, W. B., & Gross, R. (2022) · BMC Cardiovascular Disorders · doi:10.1186/s12872-022-02939-5 · Cited by 7 · see citing works
Total white blood cell count, liver enzymes, and metabolic syndrome in schizophrenia
Uğurlu, G. K., Kaymak, S. U., Ugurlu, M. M., Örsel, S., & Çayköylü, A. (2016) · TURKISH JOURNAL OF MEDICAL SCIENCES · doi:10.3906/sag-1407-60 · Cited by 7 · see citing works
An integrative network analysis framework for identifying molecular functions in complex disorders examining major depressive disorder as a test case
Oommen, A. M., Cunningham, S., O’Súilleabháin, P. S., Hughes, B. M., & Joshi, L. (2021) · Scientific Reports · doi:10.1038/s41598-021-89040-7 · Cited by 7 · see citing works
The Relationship Between Eating-Attitudes and Clinical Characteristics, Agouti-Related Peptide, and Other Biochemical Markers in Adult-Attention Deficit Hyperactivity Disorder
Gürbüzer, N., Ceyhun, H., Öztürk, N., & Kaşali, K. (2023) · Journal of Attention Disorders · doi:10.1177/10870547221149198 · Cited by 7 · see citing works
Components of the metabolic syndrome and depressive symptoms in community-dwelling older people: the Bambuí Cohort Aging Study
Ruas, L. G., Diniz, B. S., Firmo, J. O. A., Peixoto, S. V., Mambrini, J. V. D. M., Filho, A. I. D. L., Lima‐Costa, M. F., & Costa, E. (2016) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2015-1856 · Cited by 7 · see citing works
Psychische Störungen bei somatischen Krankheiten
Kapfhammer, H. (2017) · Springer eBooks · doi:10.1007/978-3-662-49295-6_88 · Cited by 6 · see citing works
Physiological and psychological effects of a 12-week home-based telemonitored training in metabolic syndrome
Köteles, É. M., Rafael, B., Korom, A., Vágvölgyi, A., Ábrahám, J. E., Domján, A., Szűcs, M., Nemes, A., Barnai, M., Lengyel, C., et al. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1075361 · Cited by 6 · see citing works
The effects of prenatal dexamethasone exposure and fructose challenge on pituitary-adrenocortical activity and anxiety-like behavior in female offspring
Manojlović‐Stojanoski, M., Nestorović, N. M., Petković, B. B., Balind, S. R., Ristić, N., Trifunović, S. L., Ajdžanović, V. Z., Filipović, B. R., Šošić‐Jurjević, B., & Milošević, V. (2019) · Tissue and Cell · doi:10.1016/j.tice.2019.101309 · Cited by 5 · see citing works
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid
Griffith, T. A., Russell, J. S., Naghipour, S., Helman, T. J., Peart, J. N., Stapelberg, N. J. C., Headrick, J. P., & Toit, E. F. D. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.121137 · Cited by 5 · see citing works
Inversely Regulated Inflammation-Related Processes Mediate Anxiety–Obesity Links in Zebrafish Larvae and Adults
Yehuda, H., Madrer, N., Goldberg, D., Soreq, H., & Meerson, A. (2023) · Cells · doi:10.3390/cells12131794 · Cited by 5 · see citing works
Investigating the association between metabolic syndrome conditions and perinatal mental illness: a national administrative claims study
Chhabria, K., Selvaraj, S., Refuerzo, J., Truong, C., & Cazaban, C. G. (2024) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-024-06542-8 · Cited by 4 · see citing works
Inflammatory Abnormalities in Major Depressive Disorder
Singhal, G., & Baune, B. T. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-58131-8.00006-9 · Cited by 4 · see citing works
Employing graph attention networks to decode psycho-metabolic interactions in Schizophrenia
Yang, H., Zhu, D., Liu, Y., Liu, Z., Liu, Z., Zhang, W., & Cai, J. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.115841 · Cited by 4 · see citing works
Qualidade de vida e síndrome metabólica em mulheres brasileiras: análise da correlação com a aptidão aeróbia e a força muscular
Teixeira, T. G., Tibana, R. A., Nascimento, D. D. C., da Silva, R. A. S., de Almeida, J. A., Bálsamo, S., Voltarelli, F. A., & Prestes, J. (2015) · Motricidade · doi:10.6063/motricidade.3543 · Cited by 4 · see citing works
Uncovering novel endocannabinoidome-gut microbiome-brain axis-based therapeutic targets in a Fragile X Syndrome mouse model
Campanale, A., Mir, H.-D., Dumais, E., Inserra, A., Flamand, N., Chakravarty, M. M., Gantois, I., Siddiqui, N., Sonenberg, N., Gobbi, G., et al. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111575 · Cited by 3 · see citing works
The endocannabinoid system in the baboon (Papio spp.) as a complex framework for developmental pharmacology
Rodriguez-Sanchez, I. P., Guindon, J., Ruiz, M., Tejero, M. E., Hubbard, G. B., Villarreal, L., Barrera-Saldaña, H. A., Dick, E. J., Comuzzie, A. G., & Schlabritz‐Loutsevitch, N. (2016) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2016.06.006 · Cited by 3 · see citing works
Effect of Metabolic Syndrome on Depression in Mice
Mukherjee, A., Sen, K. K., & Banerjee, S. (2017) · Indian Journal of Pharmaceutical Education and Research · doi:10.5530/ijper.51.4s.94 · Cited by 3 · see citing works
Metabolic syndrome and substance use: A narrative review
Kuppili, P. P., Vengadavaradan, A., & Bharadwaj, B. (2019) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2019.05.022 · Cited by 3 · see citing works
Characteristics and Correlates of Metabolic Syndrome in Adolescents with Unipolar and Bipolar Depression: Results from a Cross-National Inpatient Case–Control Study
Patel, R. S., Majumder, P., & Correll, C. U. (2022) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2022.0017 · Cited by 3 · see citing works
The Effects of Episodic Versus Continuous and Major Versus Mild Depression and Anxiety Symptoms on Pregnancy and Labour Complications
Bowen, A. (2015) · Archives of Depression and Anxiety · doi:10.17352/2455-5460.000003 · Cited by 3 · see citing works
Gender Differences in Prevalence and Clinical Correlates of Initial-Treatment and Drug-Naïve Bipolar Disorder Patients With Metabolic Syndrome: A Cross-Sectional Study
Chen, H., Chen, Y.-H., & Liu, X. (2025) · ALPHA PSYCHIATRY · doi:10.31083/ap39112 · Cited by 2 · see citing works
Early life adversity and the comorbidity of psychopathology and cardiometabolic disorders: insights from the UK Biobank
Silveira, P. P., Portella, A., Wang, Z., Hoppe, J. P. M., Pokhvisneva, I., & Meaney, M. (2025) · BMJ public health · doi:10.1136/bmjph-2025-003051 · Cited by 3 · see citing works
What MFTs should know about nutrition, psychosocial health, and collaborative care with nutrition professionals
Novak, J. R., Robinson, L., & Korn, L. E. (2021) · Journal of Marital and Family Therapy · doi:10.1111/jmft.12540 · Cited by 2 · see citing works
Profile and in-hospital outcomes of deliberate self-harmed patients in a tertiary care centre
John, J., Rashmi, K., & Jayachandran, R. (2022) · Current Medicine Research and Practice · doi:10.4103/cmrp.cmrp_33_22 · Cited by 2 · see citing works
Total oxidative stress and disease
Zeliger, H. I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91890-9.00038-6 · Cited by 2 · see citing works
Psychische Störungen bei somatischen Krankheiten
Kapfhammer, H. (2015) · Springer eBooks · doi:10.1007/978-3-642-45028-0_88-1 · Cited by 2 · see citing works
[Retracted] Prevalence and Correlation of Metabolic Syndrome in Patients with Bipolar Disorder in NGHA, Riyadh
Alanazi, A., Alsadhan, S., Aldosari, S., Al-Harbi, A., Albawardi, M., Alrabah, S., Alhawas, H., & Albalawi, M. (2022) · BioMed Research International · doi:10.1155/2022/5847175 · Cited by 2 · see citing works
Retracted
Investigation of the interaction between Genetic Risk Score (GRS) and fatty acid quality indices on mental health among overweight and obese women
Rasaei, N., Samadi, M., Khadem, A., Fatemi, S. F., Gholami, F., & Mirzaei, K. (2023) · BMC Women s Health · doi:10.1186/s12905-023-02491-0 · Cited by 2 · see citing works
Metabolic syndrome in psychiatric disorders
Shah, A. B. (2024) · Archives of Biological Psychiatry · doi:10.25259/abp_24_2023 · Cited by 1 · see citing works
The influence of metabolic dysfunction on depressive symptom trajectories: A one-year follow-up study
Longpré-Poirier, C., Garel, N., Samson-Daoust, E., Page, C. L., Romain, A. J., Guay, S., Lespérance, P., & Juster, R. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.120203 · Cited by 1 · see citing works
Longitudinal and Bidirectional Relationships Between Sleep, Emotional Wellbeing and Weight Status in Childhood and Adolescence: Growing Up in Scotland Cohort Analysis
Gale, E. L., Cecil, J. E., & Williams, A. J. (2025) · Journal of Sleep Research · doi:10.1111/jsr.70239 · Cited by 1 · see citing works
Intergenerational neurotoxicity mediated by maternal plasma metabolite profile remodeling following maternal atrazine exposure
Li, X., Fu, W., Li, J., Xu, S., Zhao, C., Gao, S., & Li, B. (2026) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2026.119973 · Cited by 1 · see citing works
Bipolar Disorder in Primary Care: Considerations in Management
Ruegg, H., Watson, S., DelBello, M. P., Adler, C. M., & Durán, L. R. P. (2018) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-018-0160-2 · Cited by 1 · see citing works
Short-term high-fat diet alters behavior, peripheral metabolism, and brain mitochondrial function in Swiss mice
Machado, A. E., REZER, P., Mancini, G., Latini, A., & Moreira, E. L. G. (2024) · Anais da Academia Brasileira de Ciências · doi:10.1590/0001-3765202420240880 · Cited by 1 · see citing works
Neurological observations
Hill, B., Daby, S., Wilcox, H., Berry, H., Newman, M., & Amoateng, G. (2025) · British Journal of Mental Health Nursing · doi:10.12968/bjmh.2024.0035 · Cited by 1 · see citing works
Comorbidity Between Severe Mental Disorders and Metabolic Disease
Starostina, E. G. (2025) · Springer eBooks · doi:10.1007/978-3-031-81802-8_8 · Cited by 1 · see citing works

The Advance of Comorbidity of Metabolic Syndrome and Psychiatric Disease
Ron, L. (2014) · Tianjin yiyao
The Psychiatric‐Metabolic Interface: Exploring the Interplay Between Mental Disorders and Metabolic Syndrome
Elias, L., Saroufine, K., Alagha, M., Beaini, C. E., Bekai, E. A., Semaan, S., Elkhoury, E., Harb, F., Azar, S. T., Khoury, N. B. E., et al. (2026) · Mental Illness · doi:10.1155/mij/4208707 · Cited by 4 · see citing works
Mental disorders and metabolic syndrome: a fatamorgana or warning reality?
Jakovljević, M., Crnčević, Ž., Ljubičić, Đ., Babić, D., Topić, R., & Šarić, M. Š. (2007) · PubMed · Cited by 47 · see citing works
Comorbidity Between Severe Mental Disorders and Metabolic Disease
Starostina, E. G. (2025) · Springer eBooks · doi:10.1007/978-3-031-81802-8_8 · Cited by 1 · see citing works
Relación entre la salud mental y la incidencia de enfermedades metabólicas
Jiménez-Gallegos, E. J. (2023) · Space Scientific Journal of Multidisciplinary · doi:10.63618/omd/ssjm/v1/n1/6

Authors: Nousen, E. K., Franco, J. G., & Sullivan, E. L.
Affiliations: Oregon National Primate Research Center (US)
ORCID: Nousen, Elizabeth K.
Sullivan, Elinor L.
Venue: Neuroendocrinology
Publisher: S. Karger AG
Published: 2013
Volume: 98
Issue: 4
Pages: 254-266
ISSN: 0028-3835 (ISSN-L)
1423-0194
DOI: 10.1159/000355632
PMC: PMC4121390
OpenAlex: W2040707068
Cited by: 123
References: 249
Citations by year: 2026: 5 · 2025: 15 · 2024: 11 · 2023: 8 · 2022: 14 · 2021: 8 · 2020: 8 · 2019: 9 · 2018: 4 · 2017: 12 · 2016: 14 · 2015: 9 · 2014: 6
FWCI: 0.63
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.karger.com/Services/SiteLicenses (vor)
www.karger.com/Services/SiteLicenses (tdm)
Locations: Neuroendocrinology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (UL1TR000128)
Oregon Clinical and Translational Research Institute
National Institute of Diabetes and Digestive and Kidney Diseases (R01DK079194)
National Center for Research Resources (P51RR000163)
National Center for Advancing Translational Sciences
Eunice Kennedy Shriver National Institute of Child Health and Human Development (L40 HD059242)
Topics: Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Keywords: metabolic syndrome, mental illness, comorbidities, inflammation, serotonergic system, dopaminergic system, neuropeptide Y, hypothalamic-pituitary-adrenal axis, maternal metabolic syndrome, fetal brain development, schizophrenia, bipolar disorder, depression, anxiety, attention deficit hyperactivity disorder, autism spectrum disorder, bidirectional relationship
MeSH terms: Animals, Mental Disorders, Female, Humans, Metabolic Diseases, Models, Neurological, Pregnancy, Prenatal Exposure Delayed Effects, Comorbidity

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Unraveling the Mechanisms Responsible for the Comorbidity between Metabolic Syndrome and Mental Health Disorders

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