Unraveling the Mechanisms Responsible for the Comorbidity between Metabolic Syndrome and Mental Health Disorders

Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication

Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052

The metabolic syndrome—a new worldwide definition

Alberti, K. G. M., Zimmet, P., & Shaw, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67402-8 · Cited by 9,352

Prevalence of Overweight and Obesity in the United States, 1999-2004

Ogden, C. L., Carroll, M. D., Curtin, L. R., McDowell, M. A., Tabak, C. J., & Flegal, K. M. (2006) · JAMA · doi:10.1001/jama.295.13.1549 · Cited by 8,720

Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010.

Flegal, K., Carroll, M., Kit, B., & Ogden, C. (2012) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.2012.39 · Cited by 5,523

Overweight, Obesity, and Depression: A Systematic Review and Meta-analysis of Longitudinal Studies

Luppino, F. S., de Wit, L. M., Bouvy, P. F., Stijnen, T., Cuijpers, P., Penninx, B. W. J. H., & Zitman, F. G. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.2 · Cited by 4,322

Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426

Antipsychotic-induced weight gain: a comprehensive research synthesis

Allison, D. B., Mentore, J. L., Heo, M., Chandler, L. P., Cappelleri, J. C., Infante, M. C., & Weiden, P. J. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.11.1686 · Cited by 2,382

Prevalence of a Metabolic Syndrome Phenotype in Adolescents: Findings From the Third National Health and Nutrition Examination Survey, 1988-1994

Cook, S., Weitzman, M., Auinger, P., Nguyen, M., & Dietz, W. H. (2003) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.157.8.821 · Cited by 2,326

The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors

Thayer, J. F., Yamamoto, S. S., & Brosschot, J. F. (2010) · International Journal of Cardiology · doi:10.1016/j.ijcard.2009.09.543 · Cited by 2,276

A comprehensive definition for metabolic syndrome

Huang, P. L. (2009) · Disease Models & Mechanisms · doi:10.1242/dmm.001180 · Cited by 2,223

Brain dopamine and obesity

Wang, G.-J., Volkow, N. D., Logan, J., Pappas, N. R., Wong, C. T., Zhu, W., Netusll, N., & Fowler, J. S. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03643-6 · Cited by 1,864

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors

Pazos, Á., & Palacios, J. M. (1985) · Brain Research · doi:10.1016/0006-8993(85)90856-x · Cited by 1,855

Stress, eating and the reward system

Adam, T. C., & Epel, E. S. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.04.011 · Cited by 1,732

Trends in the prevalence of developmental disabilities in US children, 1997-2008

Boyle, C. A., Boulet, S., Schieve, L. A., Cohen, R. A., Blumberg, S. J., Yeargin-Allsopp, M., Visser, S., & Kogan, M. D. (2011) · Pediatrics · doi:10.1542/peds.2010-2989 · Cited by 1,732

Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

Smith, S. E. P., Li, J., Garbett, K., Mirnics, K., & Patterson, P. H. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2178-07.2007 · Cited by 1,605

Depression and Type 2 Diabetes Over the Lifespan

Mezuk, B., Eaton, W. W., Albrecht, S., & Golden, S. H. (2008) · Diabetes Care · doi:10.2337/dc08-0985 · Cited by 1,558

Elevated Concentrations of CSF Corticotropin-Releasing Factor-Like Immunoreactivity in Depressed Patients

Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485

The role of corticotropin-releasing factor in depression and anxiety disorders

Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378

Association between obesity and psychiatric disorders in the US adult population

Simon, G. E., Von Korff, M., Saunders, K., Miglioretti, D. L., Crane, P. K., van Belle, G., & Kessler, R. C. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.7.824 · Cited by 1,338

Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence

Boyle, J. P., Thompson, T. J., Gregg, E. W., Barker, L. E., & Williamson, D. F. (2010) · Population Health Metrics · doi:10.1186/1478-7954-8-29 · Cited by 1,309

Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis

Kemp, A. H., Quintana, D. S., Gray, M. A., Felmingham, K. L., Brown, K., & Gatt, J. M. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.12.012 · Cited by 1,286

Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Tecott, L. H., Sun, L. M., Akana, S. F., Strack, A. M., Lowenstein, D. H., Dallman, M. F., & Julius, D. J. (1995) · Nature · doi:10.1038/374542a0 · Cited by 1,275

Relationships between obesity and DSM-IV major depressive disorder, suicide ideation, and suicide attempts: results from a general population study

Carpenter, K. M., Hasin, D. S., Allison, D. B., & Faith, M. S. (2000) · American Journal of Public Health · doi:10.2105/ajph.90.2.251 · Cited by 1,018

Fetal Origins of Obesity

Oken, E., & Gillman, M. W. (2003) · Obesity Research · doi:10.1038/oby.2003.69 · Cited by 929

Depression and obesity

Stunkard, A. J., Faith, M. S., & Allison, K. C. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00608-5 · Cited by 841

Is Obesity Associated with Major Depression? Results from the Third National Health and Nutrition Examination Survey

Onyike, C. U. (2003) · American Journal of Epidemiology · doi:10.1093/aje/kwg275 · Cited by 827

Is obesity an inflammatory condition?

Das, U. N. (2001) · Nutrition · doi:10.1016/s0899-9007(01)00672-4 · Cited by 799

Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis

for the European Depression in Diabetes (EDID) Research Consortium, Nouwen, A., Winkley, K., Twisk, J., Lloyd, C. E., Peyrot, M., Ismail, K., & Pouwer, F. (2010) · Diabetologia · doi:10.1007/s00125-010-1874-x · Cited by 756

Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic

Zhou, Q.-Y., & Palmiter, R. D. (1995) · Cell · doi:10.1016/0092-8674(95)90145-0 · Cited by 731

Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

Challier, J. C., Basu, S., Bintein, T., Minium, J., Hotmire, K., Catalano, P. M., & Hauguel-de Mouzon, S. (2008) · Placenta · doi:10.1016/j.placenta.2007.12.010 · Cited by 712

Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders

Krakowiak, P., Walker, C. K., Bremer, A. A., Baker, A. S., Ozonoff, S., Hansen, R. L., & Hertz-Picciotto, I. (2012) · PEDIATRICS · doi:10.1542/peds.2011-2583 · Cited by 675

Prospective association between obesity and depression: evidence from the Alameda County Study

Roberts, R. E., Deleger, S., Strawbridge, W. J., & Kaplan, G. A. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802204 · Cited by 674

Increased Numbers of Corticotropin-Releasing Hormone Expressing Neurons in the Hypothalamic Paraventricular Nucleus of Depressed Patients

Raadsheer, F. C., Hoogendijk, W. J. G., Stam, F. C., Tilders, F. J. H., & Swaab, D. F. (2008) · Neuroendocrinology · doi:10.1159/000126778 · Cited by 667

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia

Fillman, S. G., Cloonan, N., Catts, V. S., Miller, L. C., Wong, J., McCrossin, T., Cairns, M., & Weickert, C. S. (2013) · Molecular Psychiatry · doi:10.1038/mp.2012.110 · Cited by 609

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors

Volkow, N. D., Wang, G.-J., Telang, F., Fowler, J. S., Thanos, P. K., Logan, J., Alexoff, D., Ding, Y.-S., Wong, C., Ma, Y., et al. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.06.002 · Cited by 573

Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes

Vucetic, Z., Kimmel, J. N., Totoki, K., Hollenbeck, E., & Reyes, T. M. (2010) · Endocrinology · doi:10.1210/en.2010-0505 · Cited by 564

Reduced Corticotropin Releasing Factor Binding Sites in the Frontal Cortex of Suicide Victims

Nemeroff, C. B. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800300075009 · Cited by 555

Comparative localization of serotonin1A, 1C, and 2 receptor subtype mRNAs in rat brain

Wright, D. E., Seroogy, K. B., Lundgren, K. H., Davis, B. M., & Jennes, L. (1995) · The Journal of Comparative Neurology · doi:10.1002/cne.903510304 · Cited by 548

The relationship between mental and physical health: insights from the study of heart rate variability

Kemp, A. H., & Quintana, D. S. (2013) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2013.06.018 · Cited by 538

Inflammatory markers and depressed mood in older persons: results from the health, aging and body composition study

Penninx, B. W. J. H., Kritchevsky, S. B., Yaffe, K. S., Newman, A. B., Simonsick, E. M., Rubin, S. M., Ferrucci, L., Harris, T. B., & Pahor, M. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01811-5 · Cited by 530

Depression in Association With Severe Obesity

Dixon, J. B., Dixon, M. E., & O'Brien, P. E. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.17.2058 · Cited by 526

Binge eating disorder and obesity

de Zwaan, M. (2001) · International Journal of Obesity · doi:10.1038/sj.ijo.0801699 · Cited by 522

Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene

Gray, J. A., Yeo, G. S. H., Cox, J. J., Morton, J., Adlam, A., Keogh, J. M., Yanovski, J. A., Gharbawy, A. E., Han, J. C., Tung, Y. C. L., et al. (2006) · Diabetes · doi:10.2337/db06-0550 · Cited by 515

Obesity and mental disorders in the general population: results from the world mental health surveys

Scott, K. M., Bruffaerts, R., Simon, G. E., Alonso, J., Angermeyer, M. C., de Girolamo, G., Demyttenaere, K., Gasquet, I., Haro, J. M., Karam, E. G., et al. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803701 · Cited by 500

Prevalence and Trends of a Metabolic Syndrome Phenotype Among U.S. Adolescents, 1999–2000

Duncan, G. E., Li, S. M., & Zhou, X. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2438 · Cited by 495

Overweight and Obesity Are Associated With Psychiatric Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions

Petry, N. M., Barry, D., Pietrzak, R. H., & Wagner, J. A. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181651651 · Cited by 494

Enduring consequences of maternal obesity for brain inflammation and behavior of offspring

Bilbo, S. D., & Tsang, V. (2010) · The FASEB Journal · doi:10.1096/fj.09-144014 · Cited by 489

Levels and risks of depression and anxiety symptomatology among diabetic adults

Peyrot, M., & Rubin, R. R. (1997) · Diabetes Care · doi:10.2337/diacare.20.4.585 · Cited by 488

Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene

Nonogaki, K., Strack, A. M., Dallman, M. F., & Tecott, L. H. (1998) · Nature Medicine · doi:10.1038/2647 · Cited by 470

Bidirectional Association Between Depression and Type 2 Diabetes Mellitus in Women

Pan, A., Lucas, M., Sun, Q., van Dam, R. M., Franco, O. H., Manson, J. E., Willett, W. C., Ascherio, A., & Hu, F. B. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.356 · Cited by 460

Associations between obesity and comorbid mental health, developmental, and physical health conditions in a nationally representative sample of us children aged 10 to 17

Halfon, N., Larson, K., & Slusser, W. (2013) · Academic Pediatrics · doi:10.1016/j.acap.2012.10.007 · Cited by 429

Heartache and heartbreak—the link between depression and cardiovascular disease

Nemeroff, C. B., & Goldschmidt-Clermont, P. J. (2012) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2012.91 · Cited by 424

Depression and anxiety among US adults: associations with body mass index

Zhao, G., Ford, E. S., Dhingra, S., Li, C., Strine, T. W., & Mokdad, A. H. (2009) · International Journal of Obesity · doi:10.1038/ijo.2008.268 · Cited by 423

The neuropoietic cytokine family in development, plasticity, disease and injury

Bauer, Š., Kerr, B. J., & Patterson, P. H. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2054 · Cited by 412

Obesity Among Those with Mental Disorders

Allison, D. B., Newcomer, J. W., Dunn, A. L., Blumenthal, J. A., Fabricatore, A. N., Daumit, G. L., Cope, M. B., Riley, W. T., Vreeland, B., Hibbeln, J. R., et al. (2009) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2008.11.020 · Cited by 403

Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation

Deng, T., Lyon, C. J., Minze, L. J., Lin, J., Zou, J., Liu, J. Z., Ren, Y., Yin, Z., Hamilton, D. J., Reardon, P. R., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.02.009 · Cited by 396

Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models

Heilig, M. A., S�derpalm, B., Engel, J. A., & Widerl�v, E. (1989) · Psychopharmacology · doi:10.1007/bf00441953 · Cited by 390

Gestational Diabetes Induces Placental Genes for Chronic Stress and Inflammatory Pathways

Radaelli, T., Varastehpour, A., Catalano, P., & Hauguel-de Mouzon, S. (2003) · Diabetes · doi:10.2337/diabetes.52.12.2951 · Cited by 390

Selective Deletion ofBdnfin the Ventromedial and Dorsomedial Hypothalamus of Adult Mice Results in Hyperphagic Behavior and Obesity

Unger, T. J., Calderon, G. A., Bradley, L., Sena‐Esteves, M., & Rios, M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3308-07.2007 · Cited by 385

Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications

Alesci, S., Martinez, P. E., Kelkar, S., Ilias, I., Ronsaville, D. S., Listwak, S. J., Ayala, A. R., Licinio, J., Gold, H. K., Kling, M. A., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1667 · Cited by 372

Obesity and obesity‐related secondary conditions in adolescents with intellectual/developmental disabilities

Rimmer, J. H., Yamaki, K., Lowry, B. M. D., Wang, E., & Vogel, L. C. (2010) · Journal of Intellectual Disability Research · doi:10.1111/j.1365-2788.2010.01305.x · Cited by 354

Brain Serotonin and Dopamine Transporter Bindings in Adults With High-Functioning Autism

Nakamura, K., Sekine, Y., Ouchi, Y., Tsujii, M., Yoshikawa, E., Futatsubashi, M., Tsuchiya, K. J., Sugihara, G., Iwata, Y., Suzuki, K., et al. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.137 · Cited by 352

Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study

Goines, P. E., Croen, L. A., Braunschweig, D., Yoshida, C. K., Grether, J., Hansen, R., Kharrazi, M., Ashwood, P., & Van de Water, J. (2011) · Molecular Autism · doi:10.1186/2040-2392-2-13 · Cited by 351

Association Between Depression and Elevated C-Reactive Protein

Danner, M., Kasl, S. V., Abramson, J. L., & Vaccarino, V. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000041542.29808.01 · Cited by 341

The association between burnout, depression, anxiety, and inflammation biomarkers: C-reactive protein and fibrinogen in men and women

Toker, S., Shirom, A., Shapira, I., Berliner, S., & Melamed, S. (2005) · Journal of Occupational Health Psychology · doi:10.1037/1076-8998.10.4.344 · Cited by 340

IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation

Wei, H., Zou, H., Sheikh, A. M., Malik, M., Dobkin, C., Brown, W. T., & Li, X. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-52 · Cited by 333

Depressive mood and obesity in US adults: comparison and moderation by sex, age, and race

Heo, M., Pietrobelli, A., Fontaine, K. R., Sirey, J. A., & Faith, M. S. (2005) · International Journal of Obesity · doi:10.1038/sj.ijo.0803122 · Cited by 331

Inflammatory markers in late-life depression: Results from a population-based study

Bremmer, M. A., Beekman, A. T. F., Deeg, D. J. H., Penninx, B. W. J. H., Dik, M. G., Hack, C. E., & Hoogendijk, W. J. G. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.07.002 · Cited by 326

Chronic Consumption of a High-Fat Diet during Pregnancy Causes Perturbations in the Serotonergic System and Increased Anxiety-Like Behavior in Nonhuman Primate Offspring

Sullivan, E. L., Grayson, B. E., Takahashi, D. L., Robertson, N. D., Maier, A., Bethea, C. L., Smith, M. S., Coleman, K., & Grove, K. L. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5560-09.2010 · Cited by 324

Association of depressive disorders, depression characteristics and antidepressant medication with inflammation

Vogelzangs, N., Duivis, H. E., Beekman, A. T. F., Kluft, C., Neuteboom, J., Hoogendijk, W., Smit, J. H., de Jonge, P., & Penninx, B. W. J. H. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.8 · Cited by 323

Behavioral studies following lesions of the mesolimbic and mesostriatal serotonergic pathways

Geyer, M. A., Puerto, A., Menkes, D. B., Segal, D. S., & Mandell, A. J. (1976) · Brain Research · doi:10.1016/0006-8993(76)91024-6 · Cited by 313

Discrete neurochemical coding of distinguishable motivational processes: insights from nucleus accumbens control of feeding

Baldo, B. A., & Kelley, A. E. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0741-z · Cited by 312

Overweight in Children and Adolescents in Relation to Attention-Deficit/Hyperactivity Disorder: Results From a National Sample

Waring, M. E., & Lapane, K. L. (2008) · Pediatrics · doi:10.1542/peds.2007-1955 · Cited by 294

Association of Interleukin‐6 and Other Biologic Variables with Depression in Older People Living in the Community

Dentino, A. N., Pieper, C. F., Rao, K. M. K., Currie, M. S., Harris, T., Blazer, D. G., & Cohen, H. J. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb01894.x · Cited by 287

Maternal adiposity prior to pregnancy is associated with ADHD symptoms in offspring: evidence from three prospective pregnancy cohorts

Rodriguez, A., Miettunen, J., Henriksen, T. B., Olsen, J., Obel, C., Taanila, A. M., Ebeling, H. E., Línnet, K., Moilanen, I., & Järvelin, M. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803741 · Cited by 282

Prevalence of mental disorder in 88 morbidly obese bariatric clinic patients

Black, D. W., Goldstein, R. B., & Mason, E. E. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.2.227 · Cited by 281

Placental structure and inflammation in pregnancies associated with obesity

Roberts, K., Riley, S. C., Reynolds, R. M., Barr, S., Evans, M., Statham, A., Hor, K., Jabbour, H. N., Norman, J. E., & Denison, F. C. (2011) · Placenta · doi:10.1016/j.placenta.2010.12.023 · Cited by 281

Altered T cell responses in children with autism

Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I. N., & Van de Water, J. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.09.002 · Cited by 281

Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders

Ashwood, P., Krakowiak, P., Hertz-Picciotto, I., Hansen, R., Pessah, I. N., & Van de Water, J. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.10.025 · Cited by 279

Approaching the shared biology of obesity and depression: the stress axis as the locus of gene–environment interactions

Bornstein, S. R., Schuppenies, A., Wong, M., & Licinio, J. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001873 · Cited by 278

Role of Dopamine Receptors in ADHD: A Systematic Meta-analysis

Wu, J., Xiao, H., Sun, H., Zou, L., & Zhu, L.-Q. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8278-5 · Cited by 274

Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring

Tozuka, Y., Kumon, M., Wada, E., Onodera, M., Mochizuki, H., & Wada, K. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.05.015 · Cited by 273

Maternal High-Fat Diet Disturbs Uteroplacental Hemodynamics and Increases the Frequency of Stillbirth in a Nonhuman Primate Model of Excess Nutrition

Frias, A. E., Morgan, T. K., Evans, A. E., Rasanen, J., Oh, K. Y., Thornburg, K. L., & Grove, K. L. (2011) · Endocrinology · doi:10.1210/en.2010-1332 · Cited by 268

Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors

Wei, H., Chadman, K. K., McCloskey, D. P., Sheikh, A. M., Malik, M. N., Brown, W. T., & Li, X. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.01.011 · Cited by 267

Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice

Stenzel‐Poore, M. P., Cameron, V. A., Vaughan, J. M., Sawchenko, P. E., & Vale, W. (1992) · Endocrinology · doi:10.1210/endo.130.6.1597149 · Cited by 264

The psychobiology of comfort eating: implications for neuropharmacological interventions

Gibson, E. L. (2012) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e328357bd4e · Cited by 262

Evidence that hypophagia induced bymCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors

Kennett, G. A., & Curzon, G. (1988) · Psychopharmacology · doi:10.1007/bf02431539 · Cited by 256

Nutrient Intake From Food in Children With Autism

Hyman, S. L., Stewart, P. A., Schmidt, B., Cain, U., Lemcke, N., Foley, J. T., Peck, R., Clemons, T., Reynolds, A., Johnson, C., et al. (2012) · Pediatrics · doi:10.1542/peds.2012-0900l · Cited by 255

Pregravid Obesity Associates With Increased Maternal Endotoxemia and Metabolic Inflammation

Basu, S., Haghiac, M., Surace, P., Challier, J.-C., Guerre-Millo, M., Singh, K., Waters, T. P., Minium, J., Presley, L. H., Catalano, P. M., et al. (2010) · Obesity · doi:10.1038/oby.2010.215 · Cited by 253

Risk of completed suicide after bariatric surgery: a systematic review

Peterhänsel, C., Petroff, D., Klinitzke, G., Kersting, A., & Wagner, B. (2013) · Obesity Reviews · doi:10.1111/obr.12014 · Cited by 240

Psychosocial functioning in the obese before and after weight reduction: construct validity and responsiveness of the Obesity-related Problems scale

Karlsson, J., Taft, C., Sjöström, L., Torgerson, J., & Sullivan, M. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.0802272 · Cited by 238

Maternal pre‐pregnancy obesity and risk for inattention and negative emotionality in children

Rodriguez, A. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2009.02133.x · Cited by 233

Metabolic syndrome and mental illness.

Newcomer, J. W. (2007) · PubMed · Cited by 232

Transcranial direct current stimulation (tDCS) in unipolar vs. bipolar depressive disorder

Brunoni, A. R., Ferrucci, R., Bortolomasi, M., Vergari, M., Tadini, L., Boggio, P. S., Giacopuzzi, M., Barbieri, S., & Priori, A. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.09.010 · Cited by 226

Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8

Ellman, L. M., Deicken, R. F., Vinogradov, S., Kremen, W. S., Poole, J. H., Kern, D. M., Tsai, W. Y., Schaefer, C. A., & Brown, A. S. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.05.014 · Cited by 225

Longitudinal Evidence for Unfavorable Effects of Antidepressants on Heart Rate Variability

Licht, C. M. M., de Geus, E. J. C., van Dyck, R., & Penninx, B. W. J. H. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.032 · Cited by 225

A possible role of neuropeptide Y in depression and stress

Morales‐Medina, J. C., Dumont, Y., & Quirion, R. (2009) · Brain Research · doi:10.1016/j.brainres.2009.09.077 · Cited by 217

Maternal high fat diet consumption during the perinatal period programs offspring behavior

Sullivan, E. L., Nousen, E. K., & Chamlou, K. A. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.07.014 · Cited by 217

Hyperphagia and Increased Growth in Rats After Intraventricular Injection of 5,7-Dihydroxytryptamine

Saller, C. F., & Stricker, E. M. (1976) · Science · doi:10.1126/science.1257774 · Cited by 214

Waist circumference, abdominal obesity, and depression among overweight and obese U.S. adults: national health and nutrition examination survey 2005-2006

Zhao, G., Ford, E. S., Li, C., Tsai, J., Dhingra, S., & Balluz, L. S. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-130 · Cited by 214

The role of BDNF in the pathophysiology and treatment of schizophrenia

Favalli, G. P. D. S., Li, J., Belmonte-de-Abreu, P. S., Wong, A. H. C., & Daskalakis, Z. J. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.09.022 · Cited by 207

Cytokine hypothesis of schizophrenia pathogenesis: Evidence from human studies and animal models

Watanabe, Y., Someya, T., & Nawa, H. (2010) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2010.02094.x · Cited by 204

Prevalence of Obesity Among Children With Chronic Conditions

Chen, A. Y., Kim, S. E., Houtrow, A. J., & Newacheck, P. W. (2009) · Obesity · doi:10.1038/oby.2009.185 · Cited by 204

The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis

Oades, R. D., Lasky-Su, J., Christiansen, H., Faraone, S. V., Sonuga-Barke, E. J. S., Banaschewski, T., Chen, W., Anney, R. J. L., Buitelaar, J. K., Ebstein, R. P., et al. (2008) · Behavioral and Brain Functions · doi:10.1186/1744-9081-4-48 · Cited by 200

Increased cerebrospinal fluid interleukin-6 levels in patients with schizophrenia and those with major depressive disorder

Sasayama, D., Hattori, K., Wakabayashi, C., Teraishi, T., Hori, H., Ota, M., Yoshida, S., Arima, K., Higuchi, T., Amano, N., et al. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.12.001 · Cited by 198

Rates and risks for co-morbid depression in patients with Type 2 diabetes mellitus: results from a community-based study

Pouwer, F., Beekman, A. T. F., Nijpels, G., Dekker, J. M., Snoek, F. J., Kostense, P. J., Heine, R. J., & Deeg, D. J. H. (2003) · Diabetologia · doi:10.1007/s00125-003-1124-6 · Cited by 197

Biological Basis of Depression in Adults with Diabetes

Champaneri, S., Wand, G. S., Malhotra, S., Casagrande, S. S., & Golden, S. H. (2010) · Current Diabetes Reports · doi:10.1007/s11892-010-0148-9 · Cited by 196

Obesity‐related dysregulation of the Tryptophan–Kynurenine metabolism: Role of age and parameters of the metabolic syndrome

Mangge, H., Summers, K. L., Meinitzer, A., Zelzer, S., Almer, G., Prassl, R., Schnedl, W. J., Reininghaus, E. Z., Paulmichl, K., Weghuber, D., et al. (2013) · Obesity · doi:10.1002/oby.20491 · Cited by 186

Association Between Adult Attention Deficit/Hyperactivity Disorder and Obesity in the US Population

Pagoto, S., Curtin, C., Lemon, S. C., Bandini, L. G., Schneider, K. L., Bodenlos, J. S., & Ma, Y. (2009) · Obesity · doi:10.1038/oby.2008.587 · Cited by 186

Unadjusted and Adjusted Prevalence of Diagnosed Depression in Type 2 Diabetes

Nichols, G. A., & Brown, J. B. (2003) · Diabetes Care · doi:10.2337/diacare.26.3.744 · Cited by 186

Interactions between NPY and CRF in the amygdala to regulate emotionality

Sajdyk, T. J., Shekhar, A., & Gehlert, D. R. (2004) · Neuropeptides · doi:10.1016/j.npep.2004.05.006 · Cited by 183

Perinatal Exposure to High-Fat Diet Programs Energy Balance, Metabolism and Behavior in Adulthood

Sullivan, E. L., Smith, M. S., & Grove, K. L. (2010) · Neuroendocrinology · doi:10.1159/000322038 · Cited by 182

Metabolic hormones, dopamine circuits, and feeding

Narayanan, N. S., Guarnieri, D. J., & Dileone, R. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.10.004 · Cited by 182

Reduced Behavioral Effects of Cocaine in Heterozygous Brain-Derived Neurotrophic Factor (BDNF) Knockout Mice

Hall, F. S., Drgonová, J., Goeb, M., & Uhl, G. R. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300192 · Cited by 180

Metabolic Syndrome Predisposes to Depressive Symptoms

Koponen, H., Jokelainen, J. J., Keinanen-Kiukaanniemi, S. M., Kumpusalo, E. A., & Vanhala, M. J. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v69n0202 · Cited by 178

Imaging of Brain Dopamine Pathways

Wang, G., Volkow, N. D., Thanos, P. K., & Fowler, J. S. (2009) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e31819a86f7 · Cited by 176

Endocrine abnormalities of obesity

Björntorp, P. A. (1995) · Metabolism · doi:10.1016/0026-0495(95)90315-1 · Cited by 171

A Longitudinal Study of Childhood Depression and Anxiety in Relation to Weight Gain

Rofey, D. L., Kolko, R. P., Iosif, A., Silk, J. S., Bost, J. E., Feng, W., Szigethy, E., Noll, R. B., Ryan, N. D., & Dahl, R. E. (2009) · Child Psychiatry & Human Development · doi:10.1007/s10578-009-0141-1 · Cited by 170

Neuroinflammation in autism spectrum disorders

El-Ansary, A. K., & AL-Ayadhi, L. Y. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-265 · Cited by 167

Maternal high-fat diet in mice programs emotional behavior in adulthood

Peleg-Raibstein, D., Luca, E., & Wolfrum, C. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.05.027 · Cited by 167

The longitudinal relation between chronic diseases and depression in older persons in the community: the Longitudinal Aging Study Amsterdam

Bisschop, M. I., Kriegsman, D. M. W., Deeg, D. J. H., Beekman, A. T. F., & van Tilburg, W. (2004) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2003.01.001 · Cited by 165

Distribution of serotonin 5‐HT1C receptor mRNA in adult rat brain

Hoffman, B. J., & Mezey, É. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)81390-0 · Cited by 160

Distribution and cellular localization of the serotonin type 2C receptor messenger RNA in human brain

Pasqualetti, M., Ori, M., Castagna, M., Marazziti, D., Cassano, G. B., & Nardi, I. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00011-1 · Cited by 154

Obesity and psychopathology in women: a three decade prospective study

Kasen, S., Cohen, P. R., Chen, H., & Must, A. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803736 · Cited by 152

Night eating syndrome: A critical review of the literature

Wal, J. S. V. (2011) · Clinical Psychology Review · doi:10.1016/j.cpr.2011.11.001 · Cited by 148

Effect of anorexic drugs on food intake and the micro-structure of eating in human subjects

Rogers, P. J., & Blundell, J. E. (1979) · Psychopharmacology · doi:10.1007/bf00427624 · Cited by 148

5-HT1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively

Andrews, N., Hogg, S., Gonzalez, L. E., & File, S. E. (1994) · European Journal of Pharmacology · doi:10.1016/0014-2999(94)00473-0 · Cited by 148

Weight Gain and Other Metabolic Adverse Effects Associated with Atypical Antipsychotic Treatment of Children and Adolescents: A Systematic Review and Meta-analysis

Almandil, N. B., Liu, Y., Murray, M. L., Besag, F., Aitchison, K. J., & Wong, I. C. K. (2013) · Pediatric Drugs · doi:10.1007/s40272-013-0016-6 · Cited by 146

Chronic Disease Risks in Young Adults With Autism Spectrum Disorder: Forewarned Is Forearmed

Tyler, C. V., Schramm, S., Karafa, M., Tang, A., & Jain, A. (2011) · American Journal on Intellectual and Developmental Disabilities · doi:10.1352/1944-7558-116.5.371 · Cited by 146

Examining the relationship between Attention-Deficit/Hyperactivity Disorder and overweight in children and adolescents

Erhart, M., Herpertz‐Dahlmann, B., Wille, N., Sawitzky-Rose, B., Hölling, H., & Ravens‐Sieberer, U. (2011) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-011-0230-0 · Cited by 139

Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population

Hotta, K., Nakamura, M., Nakamura, T., Matsuo, T., Nakata, Y., Kamohara, S., Miyatake, N., Kotani, K., Komatsu, R., Itoh, N., et al. (2009) · Journal of Human Genetics · doi:10.1038/jhg.2009.106 · Cited by 138

Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype

McKernan, D. P., Dennison, U., Gaszner, G., Cryan, J. F., & Dinan, T. G. (2011) · Translational Psychiatry · doi:10.1038/tp.2011.37 · Cited by 133

Effects of antidepressants on glucose metabolism and diabetes mellitus type 2 in adults

Deuschle, M. (2012) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32835a4206 · Cited by 130

Depression Severity, Diet Quality, and Physical Activity in Women with Obesity and Depression

Appelhans, B. M., Whited, M. C., Schneider, K. L., Ma, Y., Oleski, J. L., Merriam, P. A., Waring, M. E., Olendzki, B. C., Mann, D. M., Ockene, I. S., et al. (2012) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2012.02.006 · Cited by 129

Metabolic Imprinting in Obesity

Sullivan, E. L., & Grove, K. L. (2009) · Forum of nutrition/Bibliotheca Nutritio et dieta · doi:10.1159/000264406 · Cited by 127

Impaired Executive Function Mediates the Association between Maternal Pre-Pregnancy Body Mass Index and Child ADHD Symptoms

Buß, C., Entringer, S., Davis, E. P., Hobel, C. J., Swanson, J. M., Wadhwa, P. D., & Sandman, C. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037758 · Cited by 126

Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress

Coste, S. C., Murray, S., & Stenzel‐Poore, M. P. (2001) · Peptides · doi:10.1016/s0196-9781(01)00386-2 · Cited by 120

Obesity in Men With Childhood ADHD: A 33-Year Controlled, Prospective, Follow-up Study

Cortese, S., Ramos-Olazagasti, M. A., Klein, R. G., Castellanos, F. X., Proal, E., & Mannuzza, S. (2013) · PEDIATRICS · doi:10.1542/peds.2012-0540 · Cited by 114

High Maternal Intake of Polyunsaturated Fatty Acids During Pregnancy in Mice Alters Offsprings’ Aggressive Behavior, Immobility in the Swim Test, Locomotor Activity and Brain Protein Kinase C Activity

Raygada, M. J., Cho, E., & Hilakivi‐Clarke, L. (1998) · Journal of Nutrition · doi:10.1093/jn/128.12.2505 · Cited by 113

Obesity and suicide risk in adults—A systematic review

Klinitzke, G., Steinig, J., Blüher, M., Kersting, A., & Wagner, B. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.07.010 · Cited by 112

Increased Serotonin and Dopamine Transporter Binding in Psychotropic Medication–Naïve Patients with Generalized Social Anxiety Disorder Shown by123I-β-(4-Iodophenyl)-Tropane SPECT

van der Wee, N. J., Veen, J. F. V., Stevens, H., van Vliet, I. M., van Rijk, P. P., & Westenberg, H. G. M. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.045518 · Cited by 107

Association of ADHD, tics, and anxiety with dopamine transporter ( DAT1 ) genotype in autism spectrum disorder

Gadow, K. D., Roohi, J., DeVincent, C. J., & Hatchwell, E. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01952.x · Cited by 103

Reduced neuropeptide Y mRNA levels in the frontal cortex of people with schizophrenia and bipolar disorder

Kuromitsu, J., Yokoi, A., Kawai, T., Nagasu, T., Aizawa, T., Haga, S., & Ikeda, K. (2001) · Gene Expression Patterns · doi:10.1016/s1567-133x(01)00003-5 · Cited by 101

Metabolic syndrome and short‐term heart rate variability in young adults

Koskinen, T., Kähönen, M. A. P., Jula, A., Mattsson, N., Laitinen, T. P., Keltikangas‐Järvinen, L., Viikari, J., Välimäki, I., Rönnemaa, T., & Raitakari, O. T. (2009) · Diabetic Medicine · doi:10.1111/j.1464-5491.2009.02686.x · Cited by 101

Influence of escitalopram treatment on 5-HT1A receptor binding in limbic regions in patients with anxiety disorders

Spindelegger, C., Lanzenberger, R. R., Wadsak, W., Mien, L., Stein, P., Mitterhauser, M., Moser, U., Holik, A., Pezawas, L., Kletter, K., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.35 · Cited by 100

Maternal Health in Pregnancy and Intellectual Disability in the Offspring: A Population-Based Study

Leonard, H., de Klerk, N. H., Bourke, J., & Bower, C. I. (2005) · Annals of Epidemiology · doi:10.1016/j.annepidem.2005.05.002 · Cited by 99

Weight Gain and Glucose Dysregulation with Second-Generation Antipsychotics and Antidepressants: A Review for Primary Care Physicians

Hasnain, M., Vieweg, W. V. R., & Hollett, B. (2012) · Postgraduate Medicine · doi:10.3810/pgm.2012.07.2577 · Cited by 96

Low Cerebrospinal Fluid Transthyretin Levels in Depression: Correlations with Suicidal Ideation and Low Serotonin Function

Sullivan, G. M., Mann, J. J., Oquendo, M. A., LO, E. S., Cooper, T. B., & Gorman, J. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.11.022 · Cited by 95

Night eating syndrome: implications for severe obesity

Cleator, J., Abbott, J., Judd, P. A., Sutton, C., & Wilding, J. P. H. (2012) · Nutrition and Diabetes · doi:10.1038/nutd.2012.16 · Cited by 95

The 5-HT1B Receptor Agonist CP-94,253 Reduces Food Intake and Preserves the Behavioural Satiety Sequence

Halford, J. C. G., & Blundell, J. E. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(96)00073-x · Cited by 91

CP-94,253: a selective serotonin 1B (5-HT 1B ) agonist that promotes satiety

Lee, M. D., & Simansky, K. J. (1997) · Psychopharmacology · doi:10.1007/s002130050292 · Cited by 91

Reduction in Psychopathology following Bariatric Surgery for Morbid Obesity

Maddi, S. R., Fox, S. R., Harvey, R. H., Lu, J. L., Khoshaba, D. M., & Persico, M. (2001) · Obesity Surgery · doi:10.1381/09608920160558605 · Cited by 89

Does Diabetes Double the Risk of Depression?

O’Connor, P. J., Crain, A. L., Rush, W. A., Hanson, A. M., Fischer, L. R., & Kluznik, J. C. (2009) · The Annals of Family Medicine · doi:10.1370/afm.964 · Cited by 88

The effect of 5-hydroxytryptophan on food intake and on the anorexic action of amphetamine and fenfluramine

Blundell, J. E., & Leshem, M. (1975) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1975.tb09374.x · Cited by 88

Temporal Relationships Between Overweight and Obesity andDSM-IVSubstance Use, Mood, and Anxiety Disorders

Pickering, R. P., Goldstein, R. B., Hasin, D. S., Blanco, C., Smith, S. M. R., Huang, B., Pulay, A. J., Ruan, W. J., Saha, T. D., Stinson, F. S., et al. (2011) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.10m06077gry · Cited by 86

Central action of anorexic agents: Effects of amphetamine and fenfluramine in rats with lateral hypothalamic lesions

Blundell, J. E., & Leshem, M. (1974) · European Journal of Pharmacology · doi:10.1016/0014-2999(74)90115-0 · Cited by 86

Reduced neuropeptide Y mRNA expression in the prefrontal cortex of subjects with bipolar disorder

Caberlotto, L., & Hurd, Y. L. (1999) · Neuroreport · doi:10.1097/00001756-199906030-00022 · Cited by 86

Short-term consumption of a diet rich in fat decreases anxiety response in adult male rats

Prasad, A., & Prasad, C. V. S. R. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(96)00135-7 · Cited by 86

Lifelong Enhanced Diabetes Susceptibility and Obesity after Temporary Intrahypothalamic Hyperinsulinism during Brain Organization

Plagemann, A., Heidrich, I., Götz, F., Rohde, W., & Dörner, G. (2009) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/s-0029-1211143 · Cited by 85

THE SERTRALINE VERSUS ELECTRICAL CURRENT THERAPY FOR TREATING DEPRESSION CLINICAL STUDY (SELECT-TDCS): RESULTS OF THE CROSSOVER AND FOLLOW-UP PHASES

Valiengo, L. D. C. L., Benseñor, I. M., Goulart, A. C., de Oliveira, J. F., Zanao, T. A., Boggio, P. S., Lotufo, P. A., Fregni, F., & Brunoni, A. R. (2013) · Depression and Anxiety · doi:10.1002/da.22079 · Cited by 85

Metabolic syndrome, physical activity and cardiac autonomic function

Soares‐Miranda, L., SANDERCOCK, G. R. H., Vale, S. M. C. G., Santos, R., Abreu, S., Moreira, C. M. M., & Mota, J. A. P. S. (2012) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2281 · Cited by 83

Is ignorance bliss? Depression, antidepressants, and the diagnosis of prediabetes and type 2 diabetes.

Mezuk, B. R., Johnson‐Lawrence, V., Lee, H. E., Rafferty, J. A., Abdou, C. M., Uzogara, E. E., & Jackson, J. S. (2013) · Health Psychology · doi:10.1037/a0029014 · Cited by 83

The relationship between body mass index and mental health

McLaren, L., Beck, C. A., Patten, S. B., Fick, G. H., & Adair, C. E. (2007) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-007-0269-x · Cited by 82

Short-term heart rate variability in healthy young adults

Koskinen, T., Kähönen, M. A. P., Jula, A., Laitinen, T. P., Keltikangas‐Järvinen, L., Viikari, J. S. A., Välimäki, I. A. T., & Raitakari, O. T. (2008) · Autonomic Neuroscience · doi:10.1016/j.autneu.2008.10.011 · Cited by 82

A proposed mechanism for autism: an aberrant neuroimmune response manifested as a psychiatric disorder

Buehler, M. R. (2011) · Medical Hypotheses · doi:10.1016/j.mehy.2011.02.038 · Cited by 81

Perinatal inflammatory cytokine challenge results in distinct neurobehavioral alterations in rats: implication in psychiatric disorders of developmental origin

Tohmi, M., Tsuda, N., Watanabe, Y., Kakita, A., & Nawa, H. (2004) · Neuroscience Research · doi:10.1016/j.neures.2004.05.010 · Cited by 78

Hypothalamic substrates of metabolic imprinting

Simerly, R. B. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.023 · Cited by 78

Effects of d-amphetamine and fenfluramine on feeding patterns and activity of obese and lean Zucker rats

Grinker, J. A., Drewnowski, A., Enns, M. P., & Kissileff, H. R. (1980) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(80)90367-6 · Cited by 76

Symptoms of attention deficit hyperactivity disorder in severely obese women

Fleming, J. P., Levy, L. D., & Levitan, R. D. (2005) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/bf03354661 · Cited by 75

Metabolic Syndrome and Short-Term and Long-Term Heart Rate Variability in Elderly Free of Clinical Cardiovascular Disease: The PROOF Study

Assoumou, H.-G. N., Pichot, V., Barthélemy, J., Dauphinot, V., Celle, S., Gosse, P., Kossovsky, M. P., Gaspoz, J., & Roche, F. (2010) · Rejuvenation Research · doi:10.1089/rej.2010.1019 · Cited by 75

Brief report: The dopamine-3-receptor gene (DRD3) is associated with specific repetitive behavior in Autism Spectrum Disorder (ASD)

Staal, W. G., de Krom, M., & de Jonge, M. V. (2012) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-011-1312-z · Cited by 75

Psychosocial Correlates of Psychopathology in a National Sample of the Morbidly Obese

Maddi, S. R., Khoshaba, D. M., Persico, M., Bleecker, F., & VanArsdall, G. (1997) · Obesity Surgery · doi:10.1381/096089297765555377 · Cited by 73

Neurobehavioural deficits associated with apoptotic neurodegeneration and vulnerability for ADHD

Fredriksson, A., & Archer, T. (2004) · Neurotoxicity Research · doi:10.1007/bf03033280 · Cited by 72

Psychological Outcomes and Predictors of Initial Weight Loss Outcomes Among Severely Obese Adolescents Receiving Laparoscopic Adjustable Gastric Banding

Sysko, R., Devlin, M. J., Hildebrandt, T., Brewer, S. K., Zitsman, J. L., & Walsh, B. T. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12m07690 · Cited by 72

The Impact of the Components of Metabolic Syndrome on Heart Rate Variability: Using the NCEP‐ATP III and IDF Definitions

Min, K., Min, J., Paek, D., & Cho, S. (2008) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2008.01045.x · Cited by 72

Association of the BDNF Val66Met variation with obesity in women

Beckers, S., Peeters, A. V., Zegers, D., Mertens, I. L., Gaal, L. V., & Hul, W. V. (2008) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2008.06.008 · Cited by 72

Modifiable risk factors for schizophrenia and autism — Shared risk factors impacting on brain development

Hamlyn, J., Duhig, M., McGrath, J. J., & Scott, J. G. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.10.023 · Cited by 71

Neurobiology of Nutrition and Obesity

Morrison, C. D., & Berthoud, H. (2007) · Nutrition Reviews · doi:10.1301/nr.2007.dec.517-534 · Cited by 71

Maternal hormonal manipulations in rats cause obesity and increase medial hypothalamic norepinephrine release in male offspring

Jones, A. P., Pothos, E. N., Rada, P. V., Olster, D. H., & Hoebel, B. G. (1995) · Developmental Brain Research · doi:10.1016/0165-3806(95)00078-r · Cited by 70

Pre-pregnancy maternal overweight and obesity increase the risk for affective disorders in offspring

Robinson, M., Zubrick, S. R., Pennell, C. E., Lieshout, R. J. V., Jacoby, P. A., Beilin, L. J., Mori, T. A., Stanley, F., Newnham, J. P., & Oddy, W. H. (2012) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174412000578 · Cited by 70

Night eating syndrome: an overview

Milano, W., Rosa, M. D., Milano, L., & Capasso, A. (2011) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.2011.01353.x · Cited by 67

Changes in dopamine D2-receptor binding are associated to symptom reduction after psychotherapy in social anxiety disorder

Červenka, S., Hedman‐Lagerlöf, E., Ikoma, Y., Djurfeldt, D. R., Rück, C., Halldin, C., & Lindefors, N. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.40 · Cited by 67

The frequency and clinical significance of intra-amniotic infection and/or inflammation in women with placenta previa and vaginal bleeding: an unexpected observation

Madan, I., Romero, R. J., Kusanovic, J. P., Mittal, P., Chaiworapongsa, T., Dong, Z., Mazaki‐Tovi, S., Vaisbuch, E., Savasan, Z. A., Yeo, L., et al. (2010) · Journal of Perinatal Medicine · doi:10.1515/jpm.2010.001 · Cited by 67

Higher dopamine transporter density in Parkinson’s disease patients with depression

Felicio, A. C., Moriyama, T. S., Godeiro-Junior, C. D. O., Shih, M. C., Hoexter, M. Q., Borges, V., Silva, S. M. A., Amaro, E., de Andrade, L. A. F., Ferraz, H. B., et al. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1867-y · Cited by 65

Pre- and Postoperative Psychological Characteristics in Morbidly Obese Patients

Papageorgiou, G. M., Papakonstantinou, A., Mamplekou, E., Terzis, I., & Melissas, J. (2002) · Obesity Surgery · doi:10.1381/096089202762252307 · Cited by 62

The Efficacy of Pramipexole, a Dopamine Receptor Agonist, as an Adjunctive Treatment in Treatment-Resistant Depression: An Open-Label Trial

Hori, H., & Kunugi, H. (2012) · The Scientific World Journal · doi:10.1100/2012/372474 · Cited by 62

Changes in the cardiac autonomic regulation in children with attention deficit hyperactivity disorder (ADHD).

Tonhajzerová, I., Ondrejka, I., Adamík, P., Hrubý, R., Javorka, M., Trunkvalterova, Z., Mokrá, D., & Javorka, K. (2009) · PubMed · Cited by 59

Increased interleukin-6 and tumor necrosis factor alpha in first episode schizophrenia patients versus healthy controls.

Kubistova, A., Horáček, J., & Novák, T. (2012) · PubMed · Cited by 59

Serial Measurement of Uterine Blood Flow From Mid to Late Gestation in Growth Restricted Pregnancies Induced by Overnourishing Adolescent Sheep Dams

Wallace, J. M., Milne, J. S., MATSUZAKI, M., & Aitken, R. P. (2008) · Placenta · doi:10.1016/j.placenta.2008.05.006 · Cited by 57

Effects of BDNF, T3, and corticosterone on expression of the hypothalamic obesity gene network in vivo and in vitro

Byerly, M. S., Simon, J., Bihan-Duval, É. L., Duclos, M. J. M. J., Cogburn, L. A., & Porter, T. E. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90813.2008 · Cited by 57

Control of hyperphagia prevents obesity in BDNF heterozygous mice

Coppola, V., & Tessarollo, L. (2004) · Neuroreport · doi:10.1097/00001756-200412030-00022 · Cited by 56

Functional Genomics of Attention-Deficit/Hyperactivity Disorder (ADHD) Risk Alleles on Dopamine Transporter Binding in ADHD and Healthy Control Subjects

Spencer, T. J., Biederman, J., Faraone, S. V., Madras, B. K., Bonab, A. A., Dougherty, D. D., Batchelder, H., Clarke, A., & Fischman, A. J. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.11.010 · Cited by 54

Amphetamine induced dopamine release increases anxiety in individuals recovered from anorexia nervosa

Bailer, U., Narendran, R., Frankle, W., Himes, M. L., Duvvuri, V., Mathis, C., & Kaye, W. (2011) · International Journal of Eating Disorders · doi:10.1002/eat.20937 · Cited by 54

NPY Y1 receptors in the dorsal periaqueductal gray matter regulate anxiety in the social interaction test

Kask, A., Rägo, L., & Harro, J. (1998) · Neuroreport · doi:10.1097/00001756-199808240-00005 · Cited by 54

Inflammation: good or bad for ADHD?

Donev, R., & Thome, J. (2010) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-010-0038-7 · Cited by 54

Molecular epidemiology of major depressive disorder

Kiyohara, C., & Yoshimasu, K. (2009) · Environmental Health and Preventive Medicine · doi:10.1007/s12199-008-0073-6 · Cited by 53

Screening of Adult ADHD Among Patients Presenting for Bariatric Surgery

Alfonsson, S., Parling, T., & Ghaderi, A. (2011) · Obesity Surgery · doi:10.1007/s11695-011-0569-9 · Cited by 52

Antidepressant Use Before and After the Diagnosis of Type 2 Diabetes

Mika Kivimaki, B., Tabák, Á. G., Lawlor, D. A., Batty, G. D., Singh‐Manoux, A., Jokela, M. M., Virtanen, M., Salo, P., Oksanen, T., Pentti, J., et al. (2010) · Diabetes Care · doi:10.2337/dc09-2359 · Cited by 52

Mothers of Children Diagnosed With Attention-Deficit/Hyperactivity Disorder

Ray, G. T., Croen, L., & Habel, L. A. (2008) · Medical Care · doi:10.1097/mlr.0b013e31817e18c0 · Cited by 51

Diabetes mellitus type II as a risk factor for depression: a lower than expected risk in a general practice setting

Aarts, S., van den Akker, M., van Boxtel, M. P. J., Jolles, J., Winkens, B., & Metsemakers, J. F. M. (2009) · European Journal of Epidemiology · doi:10.1007/s10654-009-9385-0 · Cited by 50

Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta‐analysis

Vancampfort, D., Stubbs, B., Mitchell, A. J., De Hert, M., Wampers, M., Ward, P. B., Rosenbaum, S., & Correll, C. U. (2015) · World Psychiatry · doi:10.1002/wps.20252 · Cited by 1,271

Microemulsion utility in pharmaceuticals: Implications for multi-drug delivery

Callender, S. P., Mathews, J. A., Kobernyk, K., & Wettig, S. D. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.05.005 · Cited by 399

Development of prefrontal cortex

Kolk, S. M., & Rakic, P. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01137-9 · Cited by 378

Towards a multidisciplinary approach to understand and manage obesity and related diseases

Bischoff, S. C., Boirie‌, Y., Cederholm, T., Chourdakis, M., Cuerda, C., Delzenne, N. M., Deutz, N. E. P., Fouque, D. P., Genton, L., Gil, C., et al. (2016) · Clinical Nutrition · doi:10.1016/j.clnu.2016.11.007 · Cited by 223

Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer’s disease

Busquets, O., Ettcheto, M., Pallàs, M., Beas‐Zárate, C., Verdaguer, E., Auladell, C., Folch, J., & Camins, A. (2016) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2016.11.002 · Cited by 107

The Advance of Comorbidity of Metabolic Syndrome and Psychiatric Disease

Ron, L. (2014) · Tianjin yiyao

The Psychiatric‐Metabolic Interface: Exploring the Interplay Between Mental Disorders and Metabolic Syndrome

Elias, L., Saroufine, K., Alagha, M., Beaini, C. E., Bekai, E. A., Semaan, S., Elkhoury, E., Harb, F., Azar, S. T., Khoury, N. B. E., et al. (2026) · Mental Illness · doi:10.1155/mij/4208707 · Cited by 4

Mental disorders and metabolic syndrome: a fatamorgana or warning reality?

Jakovljević, M., Crnčević, Ž., Ljubičić, Đ., Babić, D., Topić, R., & Šarić, M. Š. (2007) · PubMed · Cited by 47

Comorbidity Between Severe Mental Disorders and Metabolic Disease

Starostina, E. G. (2025) · Springer eBooks · doi:10.1007/978-3-031-81802-8_8 · Cited by 2

Relación entre la salud mental y la incidencia de enfermedades metabólicas

Jiménez-Gallegos, E. J. (2023) · Space Scientific Journal of Multidisciplinary · doi:10.63618/omd/ssjm/v1/n1/6