Response of neural reward regions to food cues in autism spectrum disorders
Open accessAbstract
BACKGROUND: One hypothesis for the social deficits that characterize autism spectrum disorders (ASD) is diminished neural reward response to social interaction and attachment. Prior research using established monetary reward paradigms as a test of non-social reward to compare with social reward may involve confounds in the ability of individuals with ASD to utilize symbolic representation of money and the abstraction required to interpret monetary gains. Thus, a useful addition to our understanding of neural reward circuitry in ASD includes a characterization of the neural response to primary rewards. METHOD: We asked 17 children with ASD and 18 children without ASD to abstain from eating for at least four hours before an MRI scan in which they viewed images of high-calorie foods. We assessed the neural reward network for increases in the blood oxygenation level dependent (BOLD) signal in response to the food images RESULTS: We found very similar patterns of increased BOLD signal to these images in the two groups; both groups showed increased BOLD signal in the bilateral amygdala, as well as in the nucleus accumbens, orbitofrontal cortex, and insula. Direct group comparisons revealed that the ASD group showed a stronger response to food cues in bilateral insula along the anterior-posterior gradient and in the anterior cingulate cortex than the control group, whereas there were no neural reward regions that showed higher activation for controls than for ASD. CONCLUSION: These results suggest that neural response to primary rewards is not diminished but in fact shows an aberrant enhancement in children with ASD.
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Children with Williams syndrome and ASD display high levels of anxiety; individuals with ASD have higher levels of RRB as well as greater rates of social phobia and separation anxiety.
“In addition, although children with WS and ASD display high levels of anxiety, individuals with ASD have higher levels of RRB as well as greater rates of social phobia and separation anxiety (Cascio et al., 2012).”
From Oxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders (2014) · cites this paper as Cascio et al., 2012
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Cites
How do you feel — now? The anterior insula and human awareness
(Bud) Craig, A. D. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2555 · Cited by 6,657 · cited 7× · see citing works
“Craig AD: How do you feel–now?”
InfluentialHow do you feel? Interoception: The sense of the physiological condition of the body
Craig, A. D. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn894 · Cited by 6,006 · see citing works
Saliency, switching, attention and control: a network model of insula function
Menon, V., & Uddin, L. Q. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0262-0 · Cited by 5,592 · see citing works
Wechsler Abbreviated Scale of Intelligence
Dumont, R., Willis, J. O., Veizel, K., & Zibulsky, J. (2014) · Wiley eBooks · doi:10.1002/9781118660584.ese2519 · Cited by 5,547 · see citing works
Maldjian, J., Laurienti, P., Kraft, R., & Burdette, J. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00169-1 · Cited by 5,453 · see citing works
Empathy for Pain Involves the Affective but not Sensory Components of Pain
Singer, T., Seymour, B., O'Doherty, J., Kaube, H., Dolan, R. J., & Frith, C. D. (2004) · Science · doi:10.1126/science.1093535 · Cited by 3,929 · see citing works
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406 · cited 2× · see citing works
“The insula is important for monitoring and evaluating the impact of external stimuli on internal states [15,16] and the amygdala is involved in evaluating emotional stimuli for their novelty [17], affective significance [18,19], and biological or behavioral relevance [20,21].”
Contributions of anterior cingulate cortex to behaviour
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995) · Brain · doi:10.1093/brain/118.1.279 · Cited by 3,377 · see citing works
Interoception: the sense of the physiological condition of the body
(Bud) Craig, A. (2003) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(03)00090-4 · Cited by 2,556 · cited 1× · see citing works
“Although both groups showed increased BOLD response to food images in a similar network of regions known to mediate reward, when comparing the ASD and TD groups directly, we found greater response in the ASD group in the insula and anterior cingulate cortex (ACC), known for their roles in assessing interoceptive state…”
Region of interest analysis using an SPM toolbox
Brett, M. (2002) · NeuroImage · Cited by 2,273 · see citing works
Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens
Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-j0002.2001 · Cited by 2,244 · see citing works
The human orbitofrontal cortex: linking reward to hedonic experience
Kringelbach, M. L. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1747 · Cited by 2,180 · see citing works
Food reward: brain substrates of wanting and liking
Berridge, K. C. (1996) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(95)00033-b · Cited by 1,901 · see citing works
Pessoa, L., & Adolphs, R. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2920 · Cited by 1,794 · see citing works
Type I and Type II error concerns in fMRI research: re-balancing the scale
Lieberman, M. D., & Cunningham, W. A. (2009) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsp052 · Cited by 1,342 · see citing works
Damage to the insula disrupts addiction to cigarette smoking
Naqvi, N. H., Rudrauf, D., Damasio, H., & Bechara, A. (2007) · Science · doi:10.1126/science.1135926 · Cited by 1,245 · see citing works
“Liking” and “wanting” food rewards: Brain substrates and roles in eating disorders
Berridge, K. C. (2009) · Physiology & Behavior · doi:10.1016/j.physbeh.2009.02.044 · Cited by 1,147 · see citing works
The tempted brain eats: Pleasure and desire circuits in obesity and eating disorders
Berridge, K. C., Ho, C.-Y., Richard, J. M., & DiFeliceantonio, A. G. (2010) · Brain Research · doi:10.1016/j.brainres.2010.04.003 · Cited by 873 · see citing works
Value, pleasure and choice in the ventral prefrontal cortex
Grabenhorst, F., & Rolls, E. T. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.12.004 · Cited by 766 · see citing works
Convergence and segregation of ventral striatal inputs and outputs
GROENEWEGEN, H. J., WRIGHT, C. I., BEIJER, A. V. J., & VOORN, P. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09260.x · Cited by 684 · see citing works
Two systems of resting state connectivity between the insula and cingulate cortex
Taylor, K. S., Seminowicz, D. A., & Davis, K. D. (2009) · Human Brain Mapping · doi:10.1002/hbm.20705 · Cited by 665 · see citing works
Food Selectivity in Children with Autism Spectrum Disorders and Typically Developing Children
Bandini, L. G., Anderson, S. E., Curtin, C., Cermak, S., Evans, E. W., Scampini, R., Maslin, M., & Must, A. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.02.013 · Cited by 664 · see citing works
Chib, V. S., Rangel, A., Shimojo, S., & O'Doherty, J. P. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2575-09.2009 · Cited by 643 · see citing works
The insula and drug addiction: an interoceptive view of pleasure, urges, and decision-making
Naqvi, N. H., & Bechara, A. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0268-7 · Cited by 598 · see citing works
Individual Differences in Reward Drive Predict Neural Responses to Images of Food
Beaver, J. D., Lawrence, A. D., van Ditzhuijzen, J., Davis, M. H., Woods, A., & Calder, A. J. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.0350-06.2006 · Cited by 594 · see citing works
Cortical and limbic activation during viewing of high- versus low-calorie foods
Killgore, W. D. S., Young, A. D., Femia, L. A., Bogorodzki, P., Rogowska, J., & Yurgelun-Todd, D. A. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00191-5 · Cited by 581 · see citing works
Pictures of appetizing foods activate gustatory cortices for taste and reward
Simmons, W. K., Martin, A., & Barsalou, L. W. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhi038 · Cited by 569 · see citing works
Castellanos, E. H., Charboneau, E., Dietrich, M. S., Park, S., Bradley, B. P., Mogg, K., & Cowan, R. L. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.138 · Cited by 564 · see citing works
Self-citationHowlin, P., Mawhood, L., & Rutter, M. L. (2000) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00643 · Cited by 559 · see citing works
A comparison of eating behaviors between children with and without autism
Schreck, K. A., Williams, K., & Smith, A. F. (2004) · Journal of Autism and Developmental Disorders · doi:10.1023/b:jadd.0000037419.78531.86 · Cited by 536 · see citing works
Pharmacokinetics and Clinical Effectiveness of Methylphenidate
Kimko, H. C., Cross, J. T., & Abernethy, D. R. (1999) · Clinical Pharmacokinetics · doi:10.2165/00003088-199937060-00002 · Cited by 520 · see citing works
Disentangling pleasure from incentive salience and learning signals in brain reward circuitry
Smith, K. S., Berridge, K. C., & Aldridge, J. W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101920108 · Cited by 464 · see citing works
Scott‐Van Zeeland, A. A., Dapretto, M., Ghahremani, D. G., Poldrack, R. A., & Bookheimer, S. Y. (2010) · Autism Research · doi:10.1002/aur.122 · Cited by 458 · see citing works
Human cortical gustatory areas: A review of functional neuroimaging data
Small, D. M., Zald, D. H., Jones-Gotman, M., Zatorre, R. J., Pardo, J. V., Frey, S., & Petrides, M. (1999) · NeuroReport · doi:10.1097/00001756-199901180-00002 · Cited by 431 · see citing works
Is social attachment an addictive disorder?
Insel, T. R. (2003) · Physiology & Behavior · doi:10.1016/s0031-9384(03)00148-3 · Cited by 430 · see citing works
A Replication of the Autism Diagnostic Observation Schedule (ADOS) Revised Algorithms
GOTHAM, K., RISI, S., DAWSON, G., TAGER-FLUSBERG, H., JOSEPH, R., CARTER, A., HEPBURN, S., McMAHON, W., RODIER, P., HYMAN, S. L., et al. (2008) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31816bffb7 · Cited by 374 · see citing works
Fasting biases brain reward systems towards high‐calorie foods
Goldstone, A. P., Prechtl de Hernandez, C. G., Beaver, J. D., Muhammed, K., Croese, C., Bell, G., Durighel, G., Hughes, E., Waldman, A. D., Frost, G., et al. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06949.x · Cited by 356 · see citing works
SCHRECK, K., & WILLIAMS, K. (2006) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2005.03.005 · Cited by 355 · see citing works
Social and monetary reward learning engage overlapping neural substrates
Lin, A., Adolphs, R., & Rangel, A. (2012) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsr006 · Cited by 351 · see citing works
Finlayson, G., King, N. A., & Blundell, J. E. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2006.08.020 · Cited by 342 · see citing works
Amygdala response to both positively and negatively valenced stimuli
Garavan, H., Pendergrass, J. C., Ross, T. J., Stein, E. A., & Risinger, R. C. (2001) · Neuroreport · doi:10.1097/00001756-200108280-00036 · Cited by 312 · see citing works
Sasson, N. J., Turner‐Brown, L. M., Holtzclaw, T. N., Lam, K. S. L., & Bodfish, J. W. (2008) · Autism Research · doi:10.1002/aur.4 · Cited by 311 · see citing works
Neural systems connecting interoceptive awareness and feelings
Pollatos, O., Gramann, K., & Schandry, R. (2007) · Human Brain Mapping · doi:10.1002/hbm.20258 · Cited by 301 · see citing works
Taste representation in the human insula
Small, D. M. (2010) · Brain Structure and Function · doi:10.1007/s00429-010-0266-9 · Cited by 300 · see citing works
Processing of food pictures: Influence of hunger, gender and calorie content
Frank, S., Laharnar, N., Kullmann, S., Veit, R., Canova, C., Hegner, Y. L., Fritsche, A., & Preissl, H. T. (2010) · Brain Research · doi:10.1016/j.brainres.2010.04.030 · Cited by 298 · see citing works
Reward circuitry function in autism spectrum disorders
Dichter, G. S., Felder, J. N., Green, S. R., Rittenberg, A. M., Sasson, N. J., & Bodfish, J. W. (2012) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq095 · Cited by 296 · see citing works
Bruce, A. S., Holsen, L. M., Chambers, R. J., Martin, L. E., Brooks, W. M., Zarcone, J. R., Butler, M. G., & Savage, C. R. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.84 · Cited by 282 · see citing works
Detecting and adjusting for artifacts in fMRI time series data
Diedrichsen, J., & Shadmehr, R. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.04.039 · Cited by 276 · see citing works
Using the talairach atlas with the MNI template
Brett, M., Kalina Christoff, A., Cusack, R., & Lancaster, J. L. (2001) · NeuroImage · doi:10.1016/s1053-8119(01)91428-4 · Cited by 271 · see citing works
Gustatory responses of single neurons in the insula of the macaque monkey
Yaxley, S., Rolls, E. T., & Sienkiewicz, Z. J. (1990) · Journal of Neurophysiology · doi:10.1152/jn.1990.63.4.689 · Cited by 262 · see citing works
Opioids for hedonic experience and dopamine to get ready for it
Barbano, M. F., & Cador, M. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0521-1 · Cited by 257 · see citing works
Using fMRI to dissociate sensory encoding from cognitive evaluation of heat pain intensity
Kong, J., White, N. S., Kwong, K. K., Vangel, M. G., Rosman, I. S., Gracely, R. H., & Gollub, R. L. (2006) · Human Brain Mapping · doi:10.1002/hbm.20213 · Cited by 256 · see citing works
Valence and salience contribute to nucleus accumbens activation
Cooper, J. C., & Knutson, B. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2007.08.009 · Cited by 256 · see citing works
Olfaction and Taste Processing in Autism
Bennetto, L., Kuschner, E. S., & Hyman, S. L. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.04.019 · Cited by 247 · see citing works
Neuropsychological functioning in nonmentally retarded autistic individuals
Minshew, N. J., Muenz, L. R., Goldstein, G., & Payton, J. B. (1992) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688639208402860 · Cited by 244 · see citing works
Gustatory responses in the frontal opercular cortex of the alert cynomolgus monkey
Scott, T. R., Yaxley, S., Sienkiewicz, Z. J., & Rolls, E. T. (1986) · Journal of Neurophysiology · doi:10.1152/jn.1986.56.3.876 · Cited by 228 · see citing works
BRAIN MECHANISMS FOR SOCIAL PERCEPTION: LESSONS FROM AUTISM AND TYPICAL DEVELOPMENT
Pelphrey, K., & Carter, E. J. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1416.007 · Cited by 228 · see citing works
Di Martino, A., Shehzad, Z., Kelly, C., Roy, A. K., Gee, D. G., Uddin, L. Q., Gotimer, K., Klein, D. F., Castellanos, F. X., & Milham, M. P. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08121894 · Cited by 213 · see citing works
The Neural Mechanisms Underlying the Influence of Pavlovian Cues on Human Decision Making
Bray, S., Rangel, A., Shimojo, S., Balleine, B., & O'Doherty, J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0897-08.2008 · Cited by 193 · see citing works
Brief Report: Circumscribed Attention in Young Children with Autism
Sasson, N. J., Elison, J. T., Turner-Brown, L. M., Dichter, G. S., & Bodfish, J. W. (2011) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-010-1038-3 · Cited by 181 · see citing works
Schur, E. A., Kleinhans, N. M., Goldberg, J. H., Buchwald, D., Schwartz, M. W., & Maravilla, K. R. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.56 · Cited by 170 · see citing works
All I saw was the cake. Hunger effects on attentional capture by visual food cues
Piech, R. M., Pastorino, M. T., & Zald, D. H. (2009) · Appetite · doi:10.1016/j.appet.2009.11.003 · Cited by 170 · see citing works
von Economo neurons in autism: A stereologic study of the frontoinsular cortex in children
Santos, M., Uppal, N., Butti, C., Wicinski, B., Schmeidler, J., Giannakopoulos, P., Heinsen, H., Schmitz, C., & Hof, P. R. (2011) · Brain Research · doi:10.1016/j.brainres.2010.08.067 · Cited by 164 · see citing works
Convergence of sensory systems in the orbitofrontal cortex in primates and brain design for emotion
Rolls, E. T. (2004) · The Anatomical Record Part A Discoveries in Molecular Cellular and Evolutionary Biology · doi:10.1002/ar.a.20126 · Cited by 160 · see citing works
Neural correlates of reward in autism
Schmitz, N., Rubia, K., van Amelsvoort, T., Daly, E., Smith, A., & Murphy, D. G. M. (2008) · British Journal of Psychiatry · doi:10.1192/bjp.bp.107.036921 · Cited by 153 · see citing works
A unique role for the human amygdala in novelty detection
Blackford, J. U., Buckholtz, J. W., Avery, S. N., & Zald, D. H. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.12.083 · Cited by 153 · see citing works
Demurie, E., Roeyers, H., Baeyens, D., & Sonuga‐Barke, E. (2011) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2010.02374.x · Cited by 127 · see citing works
Temperament and Character in Adults with Asperger Syndrome
Soderstrom, H., Rastam, M., & Gillberg, C. (2002) · Autism · doi:10.1177/1362361302006003006 · Cited by 116 · see citing works
Esbensen, A. J., Bishop, S. L., Seltzer, M. M., Greenberg, J. S., & Taylor, J. L. (2010) · American Journal on Intellectual and Developmental Disabilities · doi:10.1352/1944-7558-115.4.277 · Cited by 114 · see citing works
Altered experience of emotion following bilateral amygdala damage
Tranel, D., Gullickson, G., Koch, M. G., & Adolphs, R. (2006) · Cognitive Neuropsychiatry · doi:10.1080/13546800444000281 · Cited by 103 · see citing works
Ousdal, O. T., Jensen, J., Server, A., Hariri, A. R., Nakstad, P. H., & Andreassen, O. A. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.07.066 · Cited by 102 · see citing works
Atypical brain responses to reward cues in autism as revealed by event-related potentials
Kohls, G., Peltzer, J., Schulte-Rüther, M., Kamp-Becker, I., Remschmidt, H., Herpertz-Dahlmann, B., & Konrad, K. (2011) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-011-1177-1 · Cited by 101 · see citing works
Sizoo, B. B., van den Brink, W., Eenige, M. G.-V., & van der Gaag, R. J. (2009) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0b013e3181a61dd0 · Cited by 88 · see citing works
Zeeland, A. A. S., Dapretto, M., Ghahremani, D. G., Poldrack, R. A., & Bookheimer, S. Y. (2011) · Autism · doi:10.1002/aur.122.reward · Cited by 79 · see citing works
Ohla, K., Toepel, U., le Coutre, J., & Hudry, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032434 · Cited by 76 · see citing works
Central nervous changes in social dysfunction: Autism, aggression, and psychopathy
Anckarsäter, H. S. (2006) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2006.01.008 · Cited by 46 · see citing works
Food Addiction and Neuroimaging
Zhang, Y., von Deneen, K. M., Tian, J., Gold, M. S., & Liu, Y. (2011) · Current Pharmaceutical Design · doi:10.2174/138161211795656855 · Cited by 46 · see citing works
State of expectancy modulates the neural response to visual food stimuli in humans
Malik, S., McGlone, F., & Dagher, A. (2011) · Appetite · doi:10.1016/j.appet.2011.01.005 · Cited by 38 · see citing works
Lurito (2000) · doi:10.1002/1097-0193(200007)10:3
Flagged first, then by citations
Research works printed but not linked: 2
- American Psychiatric Association DSM-IV-TR Diagnostic and statistical manual of mental disorders (4th edition) -Text revision 2000 Washington, D.C: American Psychiatric Association
- Frank S Laharnar N Kullmann S Veit R Canova C Hegner YL Fritsche A Preissl H Processing of food pictures: influence of hunger, gender, and calorie content Brain Res 2010 1350 159 166 20423700
Cited by
Sorted by citations
Evaluation of the Social Motivation Hypothesis of Autism: A Systematic Review and Meta-analysis
Clements, C. C., Zoltowski, A. R., Yankowitz, L. D., Yerys, B. E., Schultz, R. T., & Herrington, J. D. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2018.1100 · Cited by 316 · see citing works
Sensory Sensitivity and Food Selectivity in Children with Autism Spectrum Disorder
Chistol, L. T., Bandini, L. G., Must, A., Phillips, S., Cermak, S. A., & Curtin, C. (2018) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3340-9 · Cited by 297 · see citing works
Portmann, T., Yang, M., Mao, R., Panagiotakos, G., Ellegood, J., Dolen, G., Bader, P. L., Grueter, B. A., Goold, C., Fisher, E., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.036 · Cited by 245 · see citing works
Functional magnetic resonance imaging of autism spectrum disorders
Dichter, G. S. (2012) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2012.14.3/gdichter · Cited by 215 · see citing works
Interoceptive Ability and Body Awareness in Autism Spectrum Disorder
Schauder, K. B., Mash, L. E., Bryant, L. K., & Cascio, C. J. (2015) · Journal of Experimental Child Psychology · doi:10.1016/j.jecp.2014.11.002 · Cited by 187 · see citing works
Self-citationOxytocin and vasopressin systems in genetic syndromes and neurodevelopmental disorders
Francis, S. M., Sagar, A., Levin-Decanini, T., Liu, W., Carter, C. S., & Jacob, S. (2014) · Brain Research · doi:10.1016/j.brainres.2014.01.021 · Cited by 101 · see citing works
Affective neural response to restricted interests in autism spectrum disorders
Cascio, C. J., Foss‐Feig, J. H., Heacock, J., Schauder, K. B., Loring, W. A., Rogers, B. P., Pryweller, J. R., Newsom, C. R., Cockhren, J., Cao, A., et al. (2014) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12147 · Cited by 93 · see citing works
Self-citationMatheson, B. E., & Douglas, J. M. (2017) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-017-0103-7 · Cited by 81 · see citing works
Parallel social information processing circuits are differentially impacted in autism
Lewis, E. M., Stein-O’Brien, G. L., Patino, A. V., Nardou, R., Grossman, C. D., Brown, M., Bangamwabo, B., Ndiaye, N., Giovinazzo, D., Dardani, I., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.10.002 · Cited by 72 · see citing works
Reputation Management: Evidence for Ability But Reduced Propensity in Autism
Cage, E., Pellicano, E., Shah, P., & Bird, G. (2013) · Autism Research · doi:10.1002/aur.1313 · Cited by 67 · see citing works
Differentiating neural reward responsiveness in autism versus ADHD
Kohls, G., Thönessen, H., Bartley, G. K., Grossheinrich, N., Fink, G. R., Herpertz-Dahlmann, B., & Konrad, K. (2014) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2014.08.003 · Cited by 50 · see citing works
Intact hedonic responses to sweet tastes in autism spectrum disorder
Damiano, C. R., Aloi, J., Burrus, C., Garbutt, J. C., Kampov-Polevoy, A. B., & Dichter, G. S. (2014) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2013.12.003 · Cited by 31 · see citing works
An update on the neurobiology of repetitive behaviors in autism
Yerys, B. E. (2015) · International review of research in developmental disabilities · doi:10.1016/bs.irrdd.2015.06.006 · Cited by 16 · see citing works
- Authors
- Cascio, C. J., Foss-Feig, J. H., Heacock, J. L., Newsom, C. R., Cowan, R. L., Benningfield, M. M., Rogers, B. P., & Cao, A.
- Affiliations
- Vanderbilt University (US)
- Corresponding author
- Cascio, Carissa J
- Venue
- Journal of Neurodevelopmental Disorders
- Published
- 2012-05-17
- Volume
- 4
- Issue
- 1
- Pages
- 9-9
- ISSN
- 1866-1947 (ISSN-L)
- 1866-1955
- PMC
- PMC3436657
- OpenAlex
- W2136196848
- Cited by
- 76
- References
- 79
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 8 · 2020: 6 · 2019: 2 · 2018: 7 · 2017: 9 · 2016: 7 · 2015: 7 · 2014: 10 · 2013: 8 · 2012: 4
- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Neurodevelopmental Disorders (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Institutes of Health (RR024975)
- National Institute of Mental Health (K01MH090232)
- National Center for Research Resources (RR024975, UL1RR024975)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- autism spectrum disorder, food cues, primary reward, social reward, insula, anterior cingulate cortex, amygdala, nucleus accumbens, orbitofrontal cortex, children, social dysfunction
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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