Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 1,134

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Advances in Male Contraception

Open access
Page, Stephanie T., Amory, John K., Bremner, William J.·2008·Endocrine Reviews
DOI 10.1210/er.2007-0041
Open this paper in CoChat — free account

Abstract

Despite significant advances in contraceptive options for women over the last 50 yr, world population continues to grow rapidly.Scientists and activists alike point to the devastating environmental impacts that population pressures have caused, including global warming from the developed world and hunger and disease in less developed areas.Moreover, almost half of all pregnancies are still unwanted or unplanned.Clearly, there is a need for expanded, reversible, contraceptive options.Multicultural surveys demonstrate the willingness of men to participate in contraception and their female partners to trust them to do so.Notwithstanding their paucity of options, male methods including vasectomy and condoms account for almost one third of contraceptive use in the United States and other countries.Recent international clinical research efforts have demonstrated high efficacy rates (90 -95%) for hormonally based male contraceptives.Current barriers to expanded use include limited delivery methods and perceived regulatory obstacles, which stymie introduction to the marketplace.However, advances in oral and injectable androgen delivery are cause for optimism that these hurdles may be overcome.Nonhormonal methods, such as compounds that target sperm motility, are attractive in their theoretical promise of specificity for the reproductive tract.Gene and protein array technologies continue to identify potential targets for this approach.Such nonhormonal agents will likely reach clinical trials in the near future.Great strides have been made in understanding male reproductive physiology; the combined efforts of scientists, clinicians, industry and governmental funding agencies could make an effective, reversible, male contraceptive an option for family planning over the next decade.(Endocrine Reviews 29: 465-493, 2008) I. Introduction II.Acceptability of Male Contraception III.Currently Available Male Contraceptive Methods A. Condoms B. Vasectomy IV.Regulation of Testicular Function and Spermatogenesis A. The hypothalamic-pituitary axis: control of gonadotropin secretion B. Testosterone production and androgen action C. Spermatogenesis D. The epididymis V. Male Hormonal Contraception Methods A. Hormonal contraceptive efficacy B. Testosterone alone C. Testosterone-progestin combinations D. Adding GnRH analogs to hormonal contraceptive regimens E. Oral male hormonal contraceptive development F. Reversibility of male hormonal contraception G. Side effects of male hormonal contraceptives H. Selective androgen receptor modulators for male contraception I. Why doesn't hormonal contraception work for all men?VI.Nonhormonal Methods A. Testicular targets B. Epdidymal targets C. Targeting sperm motility or sperm-egg fusion D. Immunological approaches to contraception VII.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1210/er.2007-0041

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 23 references

Cited by

Metadata

Authors
Page, S. T., Amory, J. K., & Bremner, W. J.
Venue
Endocrine Reviews
Publisher
The Endocrine Society
Published
2008-04-24
Volume
29
Issue
4
Pages
465-493
ISSN
  • 0163-769X (ISSN-L)
  • 1945-7189
DOI
10.1210/er.2007-0041
OpenAlex
W2007984040
Cited by
1,134
References
23
FWCI
261.60
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.