Cited by 1,362Pituitary Gland Disorders and TreatmentsAdrenal and Paraganglionic TumorsElectrolyte and hormonal disorders

Diagnosis and complications of Cushing’s syndrome: a consensus statement

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Arnaldi, G., Angeli, A., Atkinson, A. B., Bertagna, X., Cavagnini, F., Chrousos, G. P., Fava, G. A., Findling, J. W. +12 more·2003·The Journal of Clinical Endocrinology & Metabolism

Abstract

In October 2002, a workshop was held in Ancona, Italy, to reach a Consensus on the management of Cushing's syndrome. The workshop was organized by the University of Ancona and sponsored by the Pituitary Society, the European Neuroendocrine Association, and the Italian Society of Endocrinology. Invited international participants included almost 50 leading endocrinologists with specific expertise in the management of Cushing's syndrome. The consensus statement on diagnostic criteria and the diagnosis and treatment of complications of this syndrome reached at the workshop is hereby summarized.

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Crossref · 10.1210/jc.2003-030871

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84 of 84 references verified0 citation errors · 0 not checkable

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Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Controlling hypercortisolism is the first step toward improving glucose metabolism in endogenous Cushing syndrome, but different treatments may affect diabetes outcome regardless of how well cortisol excess is corrected.

    “Controlling hypercortisolism is the first step toward improving glucose metabolism in patients with endogenous CS, but different treatments for hypercortisolism may affect the outcome of diabetes, regardless of how well cortisol excess is corrected (, , , , , , ).”
  • Low-dose dexamethasone suppression testing has been used to diagnose subclinical hypercortisolism without advantages, except possibly in patients with alcoholism, psychiatric disorders, or diabetes.

    “Similarly, LDDST has been used to diagnose SH (18,40,41,55) without advantages, with the exception of patients affected with alcoholism, psychiatric disorders, and diabetes in whom this test may be more accurate (1,14,66).”

    From Diagnosis and Treatment of Subclinical Hypercortisolism (2011) · cites this paper as [66]

  • Higher dexamethasone doses of 3 or 8 mg did not show better performance for diagnosing subclinical hypercortisolism.

    “some authors have proposed higher (3 or 8 mg) dexamethasone doses (40,46,54,56), which however did not show a better performance (14,23,66).”

    From Diagnosis and Treatment of Subclinical Hypercortisolism (2011) · cites this paper as [66]

  • ACTH levels above 20 pg/ml or below 10 pg/ml suggest an ACTH-dependent or ACTH-independent cause of subclinical hypercortisolism, respectively.

    “In particular, ACTH levels above 20 pg/ml (4.4 pmol/liter) or below 10 pg/ml (2.2 pmol/liter) suggest an ACTH-dependent or -independent cause of SH, respectively (66).”

    From Diagnosis and Treatment of Subclinical Hypercortisolism (2011) · cites this paper as [66]

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Authors
Arnaldi, G., Angeli, A., Atkinson, A. B., Bertagna, X., Cavagnini, F., Chrousos, G. P., Fava, G. A., Findling, J. W., Gaillard, R. C., Grossman, A. B., Kola, B., Lacroix, A., Mancini, T., Mantero, F., Newell-Price, J., Nieman, L. K., Sonino, N., Vance, M. L., Giustina, A., & Boscaro, M.
Affiliations
  • Azienda Ospedaliero-Universitaria delle Marche (IT)
  • University of Turin (IT)
  • Royal Victoria Hospital (GB)
  • Inserm (FR)
  • University of Milan (IT)
  • National Institutes of Health (US)
  • University of Bologna (IT)
  • Aurora St. Luke's Medical Center (US)
  • St Bartholomew's Hospital (GB)
  • Centre Hospitalier de l’Université de Montréal (CA)
  • University of Padua (IT)
  • Northern General Hospital (GB)
  • University of Virginia Health System (US)
  • University of Brescia (IT)
Corresponding author
Arnaldi, G.
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
2003-12
Volume
88
Issue
12
Pages
5593-5602
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2061962280
Cited by
1,362
References
84
Citations by year
2026: 26 · 2025: 35 · 2024: 32 · 2023: 41 · 2022: 62 · 2021: 51 · 2020: 103 · 2019: 58 · 2018: 42 · 2017: 55 · 2016: 54 · 2015: 73 · 2014: 74 · 2013: 71 · 2012: 69
FWCI
26.31
Type
journal article
Language
en
Licence
other-oa
Locations
  • The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
  • PubMed (publishedVersion)
  • IRIS (submittedVersion)
  • Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
  • Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
  • SERVAL (Université de Lausanne) (submittedVersion)
  • INFM-OAR (INFN Catania) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
  • Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Electrolyte and hormonal disorders
Keywords
Cushing's syndrome, diagnostic criteria, hypercortisolism, complication treatment, consensus statement
MeSH terms
Mental Disorders, Cardiovascular Diseases, Cognition Disorders, Cushing Syndrome, Diagnosis, Differential, Humans, Osteoporosis

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