The DOI matches its Crossref record; 153 of the 156 references it cites were found in a registry or an index.
Dietary Nitrate and Nitric Oxide Metabolism: Mouth, Circulation, Skeletal Muscle, and Exercise Performance
Open accessAbstract
Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in myriad physiological processes, including the regulation of vascular tone, neurotransmission, mitochondrial respiration, and skeletal muscle contractile function. NO may be produced via the canonical NO synthase–catalyzed oxidation of l -arginine and also by the sequential reduction of nitrate to nitrite and then NO. The body’s nitrate stores can be augmented by the ingestion of nitrate-rich foods (primarily green leafy vegetables). NO bioavailability is greatly enhanced by the activity of bacteria residing in the mouth, which reduce nitrate to nitrite, thereby increasing the concentration of circulating nitrite, which can be reduced further to NO in regions of low oxygen availability. Recent investigations have focused on promoting this nitrate–nitrite–NO pathway to positively affect indices of cardiovascular health and exercise tolerance. It has been reported that dietary nitrate supplementation with beetroot juice lowers blood pressure in hypertensive patients, and sodium nitrite supplementation improves vascular endothelial function and reduces the stiffening of large elastic arteries in older humans. Nitrate supplementation has also been shown to enhance skeletal muscle function and to improve exercise performance in some circumstances. Recently, it has been established that nitrate concentration in skeletal muscle is much higher than that in blood and that muscle nitrate stores are exquisitely sensitive to dietary nitrate supplementation and deprivation. In this review, we consider the possibility that nitrate represents an essential storage form of NO and discuss the integrated function of the oral microbiome, circulation, and skeletal muscle in nitrate–nitrite–NO metabolism, as well as the practical relevance for health and performance.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Dietary nitrate, which is found in high concentrations in vegetables such as beetroot, increases NO bioavailability via the nitrate-nitrite-NO pathway, particularly in conditions of hypoxia or high metabolic demand, which are characteristic of ageing muscle [41,59,185,186].”
From Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations (2026) · cites this paper as [185]
In the citing paper
“Safety concerns regarding dietary nitrate primarily relate to its potential conversion into nitrosamines, also known as N-nitroso compounds (NOCs) [185,188].”
From Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations (2026) · cites this paper as [185]
In the citing paper
“vegetables provide antioxidants and bioactive compounds that enhance NO bioavailability and inhibit nitrosamine formation [185,188].”
From Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations (2026) · cites this paper as [185]
In the citing paper
“mechanisms that are particularly relevant in older adults with reduced endogenous antioxidant capacity and impaired NO signalling [185,288].”
From Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations (2026) · cites this paper as [185]
In the citing paper
“Fresh and minimally processed vegetables retain not only their native nitrate content but also vitamin C, betalains and flavonoids, which stabilise nitrite, limit oxidative degradation of NO and support S-nitrosothiol formation”
From Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations (2026) · cites this paper as [185]
In the citing paper
“The apparent lack of effect in elite endurance athletes may be a function of their athletic status (e.g., due to a superior background NO production or reduced number of Type II muscle fibres in which nitrate supplementation might be most suited to targeting conditions of hypoxia or acidosis [19,56,61,62]) as well as an interaction with the conditions of use.”
From Neither beetroot juice supplementation nor increased carbohydrate oxidation enhance economy of prolonged exercise in elite race walkers (2021) · cites this paper as [56]
Citations
Cites
Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association
Benjamin, E. J., Blaha, M. J., Chiuve, S. E., Cushman, M., Das, S. R., Deo, R., de Ferranti, S. D., Floyd, J., Fornage, M., Gillespie, C., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000485 · Cited by 12,591
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.
Go, A., Chertow, G., Fan, D., McCulloch, C., & Hsu, C.-Y. (2004) · New England Journal of Medicine · doi:10.1016/j.jvs.2004.10.020 · Cited by 11,645
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
Go, A. S., Chertow, G. M., Fan, D., McCulloch, C. E., & Hsu, C.-Y. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041031 · Cited by 11,369
HEART DISEASE AND STROKE STATISTICS–2014 UPDATE: A REPORT FROM THE AMERICAN HEART ASSOCIATION
Tarver, T. (2014) · Journal of Consumer Health on the Internet · doi:10.1080/15398285.2014.902284 · Cited by 5,595
Nitric oxide synthases: regulation and function
Forstermann, U., & Sessa, W. C. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr304 · Cited by 4,409
Nitric oxide and the immune response
Bogdan, C. (2001) · Nature Immunology · doi:10.1038/ni1001-907 · Cited by 3,447
Heidenreich, P. A., Trogdon, J. G., Khavjou, O. A., Butler, J., Dracup, K., Ezekowitz, M. D., Finkelstein, E. A., Hong, Y., Johnston, S. C., Khera, A., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31820a55f5 · Cited by 3,208
The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
Lundberg, J. O., Weitzberg, E., & Gladwin, M. T. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2466 · Cited by 2,739
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation
Cosby, K., Partovi, K. S., Crawford, J. H., Patel, R. P., Reiter, C. D., Martyr, S., Yang, B. K., Waclawiw, M. A., Zalos, G., Xu, X., et al. (2003) · Nature Medicine · doi:10.1038/nm954 · Cited by 1,807
Recommendations for Improving and Standardizing Vascular Research on Arterial Stiffness
Townsend, R. R., Wilkinson, I. B., Schiffrin, E. L., Avolio, A. P., Chirinos, J. A., Cockcroft, J. R., Heffernan, K. S., Lakatta, E. G., McEniery, C. M., Mitchell, G. F., et al. (2015) · Hypertension · doi:10.1161/hyp.0000000000000033 · Cited by 1,527
Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia
Carreau, A., Hafny‐Rahbi, B. E., Matejuk, A., Grillon, C., & Kieda, C. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01258.x · Cited by 1,246
Reducing the Global Burden of Cardiovascular Disease, Part 1
Joseph, P. G., Leong, D. P., McKee, M., Anand, S. S., Schwalm, J.-D., Teo, K. K., Mente, A., & Yusuf, S. (2017) · Circulation Research · doi:10.1161/circresaha.117.308903 · Cited by 1,135
Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises
Lakatta, E. G. (2003) · Circulation · doi:10.1161/01.cir.0000048894.99865.02 · Cited by 1,105
Physiology of Nitric Oxide in Skeletal Muscle
Stamler, J. S., & Meissner, G. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.1.209 · Cited by 1,080
Webb, A. J., Patel, N., Loukogeorgakis, S., Okorie, M., Aboud, Z., Misra, S., Rashid, R., Miall, P., Deanfield, J., Benjamin, N., et al. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.103523 · Cited by 1,078
Food sources of nitrates and nitrites: The physiologic context for potential health benefits
Hord, N. G., Tang, Y., & Bryan, N. S. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.27131 · Cited by 1,069
Nitric oxide in skeletal muscle
Kobzik, L., Reid, M. B., Bredt, D. S., & Stamler, J. S. (1994) · Nature · doi:10.1038/372546a0 · Cited by 955
Brachial Flow-Mediated Dilation Predicts Incident Cardiovascular Events in Older Adults
Yeboah, J., Crouse, J. R., Hsu, F., Burke, G. L., & Herrington, D. M. (2007) · Circulation · doi:10.1161/circulationaha.106.678276 · Cited by 902
Reliability of Power in Physical Performance Tests
Hopkins, W. G., Schabort, E. J., & Hawley, J. A. (2001) · Sports Medicine · doi:10.2165/00007256-200131030-00005 · Cited by 827
Mitchell, G. F. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90549.2008 · Cited by 764
Bailey, S. J., Winyard, P., Vanhatalo, A., Blackwell, J. R., DiMenna, F. J., Wilkerson, D. P., Tarr, J., Benjamin, N., & Jones, A. M. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00722.2009 · Cited by 759
Self-citationDuncan, C., Dougall, H., Johnston, P., Green, S., Brogan, R., Leifert, C., Smith, L., Golden, M., & Benjamin, N. (1995) · Nature Medicine · doi:10.1038/nm0695-546 · Cited by 734
Aging and vascular endothelial function in humans
Seals, D. R., Jablonski, K. L., & Donato, A. J. (2011) · Clinical Science · doi:10.1042/cs20100476 · Cited by 725
Self-citationBiomechanics of Sprint Running
Mero, A. A., Komi, P. V., & Gregor, R. J. (1992) · Sports Medicine · doi:10.2165/00007256-199213060-00002 · Cited by 688
Benjamin, N., O'Driscoll, F., Dougall, H., Duncan, C., Smith, L., Golden, M., & McKenzie, H. (1994) · Nature · doi:10.1038/368502a0 · Cited by 665
Effects of dietary nitrate on oxygen cost during exercise
Larsen, F. J., Weitzberg, E., Lundberg, J. O., & Ekblom, B. (2007) · Acta Physiologica · doi:10.1111/j.1748-1716.2007.01713.x · Cited by 637
Inorganic Nitrate Supplementation Lowers Blood Pressure in Humans: Role for Nitrite-Derived NO
Kapil, V., Milsom, A. B., Okorie, M., Maleki-Toyserkani, S., Akram, F., Rehman, F., Arghandawi, S., Pearl, V., Benjamin, N., Loukogeorgakis, S., et al. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.153536 · Cited by 621
Govoni, M., Jansson, E. Å., Weitzberg, E., & Lundberg, J. O. (2008) · Nitric Oxide · doi:10.1016/j.niox.2008.08.003 · Cited by 602
Cigarette smoking and the oral microbiome in a large study of American adults
Wu, J., Peters, B. A., Dominianni, C., Zhang, Y., Pei, Z., Yang, L., Ma, Y., Purdue, M. P., Jacobs, E. J., Gapstur, S. M., et al. (2016) · The ISME Journal · doi:10.1038/ismej.2016.37 · Cited by 572
Direct Evidence of Endothelial Oxidative Stress With Aging in Humans
Donato, A. J., Eskurza, I., Silver, A., Levy, A., Pierce, G. L., Gates, P. E., & Seals, D. R. (2007) · Circulation Research · doi:10.1161/01.res.0000269183.13937.e8 · Cited by 566
Self-citationCellular and molecular biology of aging endothelial cells
Donato, A. J., Morgan, R. G., Walker, A. E., & Lesniewski, L. A. (2015) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2015.01.021 · Cited by 538
Vanhatalo, A., Bailey, S. J., Blackwell, J. R., DiMenna, F. J., Pavey, T. G., Wilkerson, D. P., Benjamin, N., Winyard, P. G., & Jones, A. M. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00206.2010 · Cited by 529
Self-citationBeetroot juice and exercise: pharmacodynamic and dose-response relationships
Wylie, L. J., Kelly, J., Bailey, S. J., Blackwell, J. R., Skiba, P. F., Winyard, P. G., Jeukendrup, A. E., Vanhatalo, A., & Jones, A. M. (2013) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00372.2013 · Cited by 500
Self-citationKapil, V., Khambata, R. S., Robertson, A., Caulfield, M. J., & Ahluwalia, A. (2015) · Hypertension · doi:10.1161/hypertensionaha.114.04675 · Cited by 500
Prevalence of dietary supplement use by athletes: Systematic review and meta-analysis
Knapik, J. J., Steelman, R. A., Hoedebecke, S. S., Austin, K. G., Farina, E. K., & Lieberman, H. R. (2016) · Sports Medicine · doi:10.1007/s40279-015-0387-7 · Cited by 452
Physiological role for nitrate-reducing oral bacteria in blood pressure control
Kapil, V., Haydar, S. M. A., Pearl, V., Lundberg, J. O., Weitzberg, E., & Ahluwalia, A. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.11.013 · Cited by 413
Evaluation of bacterial nitrate reduction in the human oral cavity
Doel, J. J., Benjamin, N., Hector, M. P., Rogers, M., & Allaker, R. P. (2005) · European Journal of Oral Sciences · doi:10.1111/j.1600-0722.2004.00184.x · Cited by 362
Is Flow-Mediated Dilation Nitric Oxide Mediated?
GREEN, D. J., Dawson, E. A., Groenewoud, H., Jones, H., & Thijssen, D. H. J. (2013) · Hypertension · doi:10.1161/hypertensionaha.113.02044 · Cited by 362
A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis
Jansson, E. Å., Huang, L., Malkey, R., Govoni, M., Nihlén, C., Olsson, A., Stensdotter, M., Petersson, J., Holm, L., Weitzberg, E., et al. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.92 · Cited by 356
Roles of dietary inorganic nitrate in cardiovascular health and disease
Lundberg, J. O., Carlström, M., Larsen, F. J., & Weitzberg, E. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvq325 · Cited by 355
Nitrite‐derived nitric oxide: a possible mediator of ‘acidic–metabolic’ vasodilation
Modin, A., Björne, H., Herulf, M., Alving, K., Weitzberg, E., & Lundberg, J. O. N. (2001) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2001.00771.x · Cited by 346
Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast‐twitch muscle
Hernández, A., Schiffer, T. A., Ivarsson, N., Cheng, A. J., Bruton, J. D., Lundberg, J. O., Weitzberg, E., & Westerblad, H. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.232777 · Cited by 319
Effect of Inorganic Nitrate on Exercise Capacity in Heart Failure With Preserved Ejection Fraction
Zamani, P., Rawat, D., Shiva-Kumar, P., Geraci, S., Bhuva, R., Konda, P., Doulias, P.-T., Ischiropoulos, H., Townsend, R. R., Margulies, K. B., et al. (2015) · Circulation · doi:10.1161/circulationaha.114.012957 · Cited by 307
Velmurugan, S., Gan, J. M., Rathod, K. S., Khambata, R. S., Ghosh, S. M., Hartley, A., Van Eijl, S., Sagi-Kiss, V., Chowdhury, T. A., Curtis, M., et al. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.116244 · Cited by 284
Characterization of the Magnitude and Kinetics of Xanthine Oxidase-catalyzed Nitrite Reduction
Li, H., Samouilov, A., Liu, X., & Zweier, J. L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m011648200 · Cited by 280
Hyde, E. R., Andrade, F., Vaksman, Z., Parthasarathy, K., Jiang, H., Parthasarathy, D. K., Torregrossa, A. C., Tribble, G., Kaplan, H. B., Petrosino, J. F., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088645 · Cited by 275
Roizen, M. F. (2012) · Yearbook of Anesthesiology and Pain Management · doi:10.1016/j.yane.2012.01.067 · Cited by 272
Nitrite in nitric oxide biology: Cause or consequence?
Bryan, N. S. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.05.019 · Cited by 260
Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans
Vanhatalo, A., Blackwell, J. R., L’Heureux, J. E., Williams, D. W., Smith, A., van der Giezen, M., Winyard, P. G., Kelly, J., & Jones, A. M. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.05.078 · Cited by 256
Self-citationKumar, P. S. (2017) · The Journal of Physiology · doi:10.1113/jp272427 · Cited by 241
Vascular nitric oxide: formation and function
Loscalzo, J., & Jin (2010) · Journal of Blood Medicine · doi:10.2147/jbm.s7000 · Cited by 240
Acute effect of a high nitrate diet on brain perfusion in older adults
Presley, T. D., Morgan, A. R., Bechtold, E., Clodfelter, W., Dove, R. W., Jennings, J. M., Kraft, R. A., Bruce King, S., Laurienti, P. J., Jack Rejeski, W., et al. (2011) · Nitric Oxide · doi:10.1016/j.niox.2010.10.002 · Cited by 238
Kelly, J., Fulford, J., Vanhatalo, A., Blackwell, J. R., French, O., Bailey, S. J., Gilchrist, M., Winyard, P. G., & Jones, A. M. (2013) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00406.2012 · Cited by 232
Self-citationFactors That Differentiate Acceleration Ability in Field Sport Athletes
Lockie, R. G., Murphy, A. J., Knight, T. J., & de Jonge, X. J. (2011) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0b013e31820d9f17 · Cited by 221
Wylie, L. J., Mohr, M., Krustrup, P., Jackman, S. R., Ermιdis, G., Kelly, J., Black, M. I., Bailey, S. J., Vanhatalo, A., & Jones, A. M. (2013) · European Journal of Applied Physiology · doi:10.1007/s00421-013-2589-8 · Cited by 220
Self-citationSindler, A. L., Fleenor, B. S., Calvert, J. W., Marshall, K. D., Zigler, M. L., Lefer, D. J., & Seals, D. R. (2011) · Aging Cell · doi:10.1111/j.1474-9726.2011.00679.x · Cited by 218
Self-citationCarotid Stiffness Is Associated With Incident Stroke
van Sloten, T. T., Sedaghat, S., Laurent, S., London, G. M., Pannier, B., Ikram, M. A., Kavousi, M., Mattace-Raso, F. U. S., Franco, O. H., Boutouyrie, P., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.08.888 · Cited by 217
Sialin ( SLC17A5 ) functions as a nitrate transporter in the plasma membrane
Qin, L., Liu, X., Sun, Q., Fan, Z., Xia, D., Ding, G., Ong, H. L., Adams, D., Gahl, W. A., Zheng, C., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1116633109 · Cited by 216
Endothelial Function in Resistance and Conduit Arteries and 5-Year Risk of Cardiovascular Disease
Lind, L., Berglund, L., Larsson, A. O., & Sundström, J. (2011) · Circulation · doi:10.1161/circulationaha.110.984047 · Cited by 216
The subgingival periodontal microbiota of the aging mouth
Feres, M., Teles, F., Teles, R. P., Figueiredo, L. C., & Faveri, M. (2016) · Periodontology 2000 · doi:10.1111/prd.12136 · Cited by 213
Dietary Nitrate and Physical Performance
Jones, A. M., Thompson, C., Wylie, L. J., & Vanhatalo, A. (2018) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-082117-051622 · Cited by 206
Self-citationHobbs, D. A., Kaffa, N., George, T. W., Methven, L., & Lovegrove, J. A. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512000190 · Cited by 199
Aerobic Fitness Affects the Exercise Performance Responses to Nitrate Supplementation
PORCELLI, S., RAMAGLIA, M., BELLISTRI, G., PAVEI, G., PUGLIESE, L., MONTORSI, M., RASICA, L., & MARZORATI, M. (2015) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000577 · Cited by 187
The effect of nitric oxide on mitochondrial respiration
Poderoso, J. J., Helfenberger, K. E., & Poderoso, C. (2019) · Nitric Oxide · doi:10.1016/j.niox.2019.04.005 · Cited by 183
Scuteri, A., Tesauro, M., Appolloni, S., Preziosi, F., Brancati, A. M., & Volpe, M. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e3280895b55 · Cited by 181
Li, H., Samouilov, A., Liu, X., & Zweier, J. L. (2003) · Biochemistry · doi:10.1021/bi026385a · Cited by 180
Eskurza, I., Myerburgh, L. A., Kahn, Z. D., & Seals, D. R. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.092734 · Cited by 175
Self-citationJonvik, K. L., Nyakayiru, J., Pinckaers, P. J., Senden, J. M., van Loon, L. J., & Verdijk, L. B. (2016) · The Journal of Nutrition · doi:10.3945/jn.116.229807 · Cited by 172
Self-citationNitrate Supplementation Enhances the Contractile Properties of Human Skeletal Muscle
HAIDER, G., & FOLLAND, J. P. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000351 · Cited by 166
Rammos, C., Hendgen-Cotta, U. B., Sobierajski, J., Bernard, A., Kelm, M., & Rassaf, T. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.08.691 · Cited by 165
Coggan, A. R., Leibowitz, J. L., Kadkhodayan, A., Thomas, D. P., Ramamurthy, S., Spearie, C. A., Waller, S., Farmer, M., & Peterson, L. R. (2015) · Nitric Oxide · doi:10.1016/j.niox.2014.08.014 · Cited by 159
Gilchrist, M., Winyard, P. G., & Benjamin, N. (2010) · Nitric Oxide · doi:10.1016/j.niox.2009.10.005 · Cited by 157
Thompson, C., Wylie, L. J., Fulford, J., Kelly, J., Black, M. I., McDonagh, S. T. J., Jeukendrup, A. E., Vanhatalo, A., & Jones, A. M. (2015) · European Journal of Applied Physiology · doi:10.1007/s00421-015-3166-0 · Cited by 156
Self-citationStrategies for Achieving Healthy Vascular Aging
Nowak, K. L., Rossman, M. J., Chonchol, M., & Seals, D. R. (2018) · Hypertension · doi:10.1161/hypertensionaha.117.10439 · Cited by 155
Self-citationJackson, J. K., Patterson, A. J., MacDonald‐Wicks, L. K., Oldmeadow, C. J., & McEvoy, M. (2018) · Nutrition Reviews · doi:10.1093/nutrit/nuy005 · Cited by 155
Fiber Type-Specific Effects of Dietary Nitrate
Jones, A. M., Ferguson, S. K., Bailey, S. J., Vanhatalo, A., & Poole, D. C. (2016) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000074 · Cited by 149
Self-citationPermeation and Block of the Skeletal Muscle Chloride Channel, ClC-1, by Foreign Anions
Rychkov, G. Y., Pusch, M., Roberts, M. L., Jentsch, T. J., & Bretag, A. H. (1998) · The Journal of General Physiology · doi:10.1085/jgp.111.5.653 · Cited by 148
De Filippis, F., Vannini, L., La Storia, A., Laghi, L., Piombino, P., Stellato, G., Serrazanetti, D. I., Gozzi, G., Turroni, S., Ferrocino, I., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112373 · Cited by 146
Ergogenic Effect of Nitrate Supplementation: A Systematic Review and Meta-analysis
Senefeld, J. W., Wiggins, C. C., Regimbal, R. J., Dominelli, P. B., Baker, S. E., & Joyner, M. J. (2020) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002363 · Cited by 146
Jones, A. M. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2014-0036 · Cited by 144
Self-citationBeetroot Juice Supplementation Does Not Improve Performance of Elite 1500-m Runners
BOORSMA, R. K., WHITFIELD, J., & SPRIET, L. L. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000364 · Cited by 142
On the ecosystemic network of saliva in healthy young adults
Zaura, E., Brandt, B. W., Prodan, A., Teixeira de Mattos, M. J., Imangaliyev, S., Kool, J., Buijs, M. J., Jagers, F. L. P. W., Hennequin-Hoenderdos, N. L., Slot, D. E., et al. (2017) · The ISME Journal · doi:10.1038/ismej.2016.199 · Cited by 142
Burke, L. M. (2017) · Sports Medicine · doi:10.1007/s40279-017-0687-1 · Cited by 141
Nitrate and Nitrites in Foods: Worldwide Regional Distribution in View of Their Risks and Benefits
Kalaycıoğlu, Z., & Erim, F. B. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b01194 · Cited by 140
Influence of nitrate supplementation on VO2 kinetics and endurance of elite cyclists
Christensen, P. M., Nyberg, M., & Bangsbo, J. (2013) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/sms.12005 · Cited by 138
Coggan, A. R., Leibowitz, J. L., Spearie, C. A., Kadkhodayan, A., Thomas, D. P., Ramamurthy, S., Mahmood, K., Park, S., Waller, S., Farmer, M., et al. (2015) · Circulation Heart Failure · doi:10.1161/circheartfailure.115.002141 · Cited by 136
Skeletal muscle nNOSμ protein content is increased by exercise training in humans
McConell, G. K., Bradley, S. J., Stephens, T. J., Canny, B. J., Kingwell, B. A., & Lee-Young, R. S. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00796.2006 · Cited by 136
Influence of beetroot juice supplementation on intermittent exercise performance
Wylie, L. J., Bailey, S. J., Kelly, J., Blackwell, J. R., Vanhatalo, A., & Jones, A. M. (2016) · European Journal of Applied Physiology · doi:10.1007/s00421-015-3296-4 · Cited by 133
Self-citationDietary nitrate supplementation improves sprint and high-intensity intermittent running performance
Thompson, C., Vanhatalo, A., Jell, H., Fulford, J., Carter, J., Nyman, L., Bailey, S. J., & Jones, A. M. (2016) · Nitric Oxide · doi:10.1016/j.niox.2016.10.006 · Cited by 130
Self-citationImpact of a vegan diet on the human salivary microbiota
Hansen, T. H., Kern, T., Bak, E. G., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. F., & Pedersen, O. B. (2018) · Scientific Reports · doi:10.1038/s41598-018-24207-3 · Cited by 127
Dietary Nitrate Does Not Enhance Running Performance in Elite Cross-Country Skiers
PEACOCK, O., TJØNNA, A. E., JAMES, P., WISLØFF, U., WELDE, B., BÖHLKE, N., SMITH, A., STOKES, K., COOK, C., & SANDBAKK, Ø. (2012) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3182640f48 · Cited by 126
Ferguson, S. K., Holdsworth, C. T., Wright, J. L., Fees, A. J., Allen, J. D., Jones, A. M., Musch, T. I., & Poole, D. C. (2015) · Nitric Oxide · doi:10.1016/j.niox.2014.09.157 · Cited by 120
Self-citationTribble, G. D., Angelov, N., Weltman, R. L., Wang, B., Eswaran, S. V. K., Gay, I. C., Parthasarathy, K., Dao, D.-H. V., Richardson, K. N., Ismail, N. M., et al. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00039 · Cited by 118
Santolini, J., Meade, A. L., & Stuehr, D. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m108666200 · Cited by 116
Human skeletal muscle nitrate store: Influence of dietary nitrate supplementation and exercise
Wylie, L. J., Park, J. W., Vanhatalo, A., Kadach, S., Black, M. I., Stoyanov, Z., Schechter, A. N., Jones, A. M., & Piknova, B. (2019) · The Journal of Physiology · doi:10.1113/jp278076 · Cited by 116
Self-citationNyakayiru, J., Jonvik, K., Trommelen, J., Pinckaers, P., Senden, J., Van Loon, L., & Verdijk, L. (2017) · Nutrients · doi:10.3390/nu9030314 · Cited by 115
Self-citationPoroca, D. R., Pelis, R. M., & Chappe, V. M. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00151 · Cited by 111
Ashworth, A., Mitchell, K., Blackwell, J. R., Vanhatalo, A., & Jones, A. M. (2015) · Public Health Nutrition · doi:10.1017/s1368980015000038 · Cited by 109
Self-citationSkeletal muscle as an endogenous nitrate reservoir
Piknova, B., Park, J. W., Swanson, K. M., Dey, S., Noguchi, C. T., & Schechter, A. N. (2015) · Nitric Oxide · doi:10.1016/j.niox.2015.02.145 · Cited by 108
Self-citationReview of ‘the Potential Role of Arterial Stiffness in the Pathogenesis of Alzheimer’s Disease’
Hughes, T. M., Craft, S., & López, O. L. (2015) · Neurodegenerative Disease Management · doi:10.2217/nmt.14.53 · Cited by 105
Over-the-counter mouthwash use and risk of pre-diabetes/diabetes
JOSHIPURA, K. J., Muñoz‐Torres, F. J., Morou-Bermúdez, E., & Patel, R. P. (2017) · Nitric Oxide · doi:10.1016/j.niox.2017.09.004 · Cited by 105
Burleigh, M. C., Liddle, L., Muggeridge, D. J., Monaghan, C., Sculthorpe, N. F., Butcher, J. P., Henriquez, F. L., & Easton, C. (2019) · Nitric Oxide · doi:10.1016/j.niox.2019.04.010 · Cited by 101
Kina-Tanada, M., Sakanashi, M., Tanimoto, A., Kaname, T., Matsuzaki, T., Noguchi, K., Uchida, T., Nakasone, J., Kozuka, C., Ishida, M., et al. (2017) · Diabetologia · doi:10.1007/s00125-017-4259-6 · Cited by 97
Effects of a nitrate-rich meal on arterial stiffness and blood pressure in healthy volunteers
Liu, A. H., Bondonno, C. P., Croft, K. D., Puddey, I. B., Woodman, R. J., Rich, L., Ward, N. C., Vita, J. A., & Hodgson, J. M. (2013) · Nitric Oxide · doi:10.1016/j.niox.2013.10.001 · Cited by 93
Vascular nitric oxide: effects of physical activity, -importance for health
McAllister, R. M., & Laughlin, M. H. (2006) · Essays in Biochemistry · doi:10.1042/bse0420119 · Cited by 92
Ahluwalia, A., Gladwin, M., Coleman, G. D., Hord, N., Howard, G., Kim‐Shapiro, D. B., Lajous, M., Larsen, F. J., Lefer, D. J., McClure, L. A., et al. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.116.003402 · Cited by 92
Lauer, T., Heiss, C., Balzer, J., Kehmeier, E., Mangold, S., Leyendecker, T., Rottler, J., Meyer, C., Merx, M. W., Kelm, M., et al. (2008) · Basic Research in Cardiology · doi:10.1007/s00395-008-0714-3 · Cited by 88
Peeling, P., Cox, G. R., Bullock, N., & Burke, L. M. (2015) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2014-0110 · Cited by 87
Goh, C. E., Trinh, P., Colombo, P. C., Genkinger, J. M., Mathema, B., Uhlemann, A., LeDuc, C. A., Leibel, R. L., Rosenbaum, M. S., Paster, B. J., et al. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.013324 · Cited by 87
Fleenor, B. S., Sindler, A. L., Eng, J. S., Nair, D. P., Dodson, R. B., & Seals, D. R. (2012) · Experimental Gerontology · doi:10.1016/j.exger.2012.05.004 · Cited by 85
Self-citationHealthy lifestyle-based approaches for successful vascular aging
Rossman, M. J., LaRocca, T. J., Martens, C. R., & Seals, D. R. (2018) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00521.2018 · Cited by 85
Self-citationDeVan, A. E., Johnson, L. C., Brooks, F. A., Evans, T. D., Justice, J. N., Cruickshank-Quinn, C. I., Reisdorph, N. A., Bryan, N. S., McQueen, M. B., Santos‐Parker, J. R., et al. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00879.2015 · Cited by 84
Self-citationNutrition and other lifestyle influences on arterial aging
LaRocca, T. J., Martens, C. R., & Seals, D. R. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2016.09.002 · Cited by 83
Self-citationBeetroot Juice Increases Human Muscle Force without Changing Ca2+-Handling Proteins
WHITFIELD, J., GAMU, D., HEIGENHAUSER, G. J. F., VAN LOON, L. J. C., SPRIET, L. L., TUPLING, A. R., & HOLLOWAY, G. P. (2017) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001321 · Cited by 83
Pawlak-Chaouch, M., Boissière, J., Gamelin, F. X., Cuvelier, G., Berthoin, S., & Aucouturier, J. (2016) · Nitric Oxide · doi:10.1016/j.niox.2016.01.001 · Cited by 81
McDonagh, S., Wylie, L., Winyard, P., Vanhatalo, A., & Jones, A. (2015) · International Journal of Sports Medicine · doi:10.1055/s-0035-1554700 · Cited by 79
Self-citationWickham, K. A., & Spriet, L. L. (2019) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2019-0063 · Cited by 78
Nitric oxide and muscle blood flow in exercise
Tschakovsky, M. E., & Joyner, M. J. (2008) · Applied Physiology Nutrition and Metabolism · doi:10.1139/h07-148 · Cited by 75
Nitrate as a source of nitrite and nitric oxide during exercise hyperemia in rat skeletal muscle
Piknova, B., Park, J. W., Kwan (Jeff) Lam, K., & Schechter, A. N. (2016) · Nitric Oxide · doi:10.1016/j.niox.2016.03.005 · Cited by 75
Self-citationInorganic nitrite supplementation for healthy arterial aging
Sindler, A. L., DeVan, A. E., Fleenor, B. S., & Seals, D. R. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01100.2013 · Cited by 68
Self-citationSandbakk, S. B., Sandbakk, Ø., Peacock, O., James, P., Welde, B., Stokes, K., Böhlke, N., & Tjønna, A. E. (2015) · Nitric Oxide · doi:10.1016/j.niox.2014.10.006 · Cited by 66
Effects of a Short-Term High-Nitrate Diet on Exercise Performance
Porcelli, S., Pugliese, L., Rejc, E., Pavei, G., Bonato, M., Montorsi, M., Torre, A. L., Rasica, L., & Marzorati, M. (2016) · Nutrients · doi:10.3390/nu8090534 · Cited by 66
Large elastic artery stiffness with aging: novel translational mechanisms and interventions.
Fleenor, B. S. (2013) · Europe PMC (PubMed Central) · Cited by 63
Effect of dietary nitrate levels on nitrate fluxes in rat skeletal muscle and liver
Gilliard, C. N., Lam, J. K., Cassel, K. S., Park, J. W., Schechter, A. N., & Piknova, B. (2018) · Nitric Oxide · doi:10.1016/j.niox.2018.01.010 · Cited by 63
Self-citationThe role of vascular myoglobin in nitrite-mediated blood vessel relaxation
Ormerod, J. O. M., Ashrafian, H., Maher, A. R., Arif, S., Steeples, V., Born, G. V. R., Egginton, S., Feelisch, M., Watkins, H., & Frenneaux, M. P. (2011) · Cardiovascular Research · doi:10.1093/cvr/cvq299 · Cited by 61
Sodium nitrate ingestion increases skeletal muscle nitrate content in humans
Nyakayiru, J., Kouw, I. W. K., Cermak, N. M., Senden, J. M., van Loon, L. J. C., & Verdijk, L. B. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01036.2016 · Cited by 60
Skeletal muscle microvascular and interstitial from rest to contractions
Hirai, D. M., Craig, J. C., Colburn, T. D., Eshima, H., Kano, Y., Sexton, W. L., Musch, T. I., & Poole, D. C. (2017) · The Journal of Physiology · doi:10.1113/jp275170 · Cited by 60
Liddle, L., Burleigh, M. C., Monaghan, C., Muggeridge, D. J., Sculthorpe, N., Pedlar, C. R., Butcher, J., Henriquez, F. L., & Easton, C. (2019) · Nitric Oxide · doi:10.1016/j.niox.2018.12.003 · Cited by 59
Jonvik, K. L., Nyakayiru, J., Van Dijk, J. W., Maase, K., Ballak, S. B., Senden, J. M. G., Van Loon, L. J. C., & Verdijk, L. B. (2018) · European Journal of Sport Science · doi:10.1080/17461391.2018.1433722 · Cited by 57
Self-citationMaia, L. B., & Moura, J. J. G. (2018) · Redox Biology · doi:10.1016/j.redox.2018.08.020 · Cited by 57
Kyriacou, M. C., Soteriou, G. A., Colla, G., & Rouphael, Y. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2019.02.001 · Cited by 57
Ashworth, A., Clarke, C., Farnham, G., Liddle, L., Burleigh, M., Rodiles, A., Sillitti, C., Kiernan, M., Moore, M., Hickson, M., et al. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.05.010 · Cited by 56
Can elite athletes benefit from dietary nitrate supplementation?
Jonvik, K. L., Nyakayiru, J., van Loon, L. J. C., & Verdijk, L. B. (2015) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00232.2015 · Cited by 55
Self-citationJustice, J. N., Johnson, L. C., DeVan, A. E., Cruickshank-Quinn, C. I., Reisdorph, N. A., Bassett, C. J., Evans, T. D., Brooks, F. A., Bryan, N. S., Chonchol, M. B., et al. (2015) · Aging · doi:10.18632/aging.100842 · Cited by 53
Self-citationBailey, S. J., Gandra, P. G., Jones, A. M., Hogan, M. C., & Nogueira, L. (2019) · The Journal of Physiology · doi:10.1113/jp278494 · Cited by 51
Self-citationRole of xanthine oxidase in reperfusion injury of ischemic skeletal muscles in the pig and human
Dorion, D., Zhong, A., Chiu, C., Forrest, C. R., Boyd, B. J., & Pang, C. Y. (1993) · Journal of Applied Physiology · doi:10.1152/jappl.1993.75.1.246 · Cited by 47
Microbiota and the nitrogen cycle: Implications in the development and progression of CVD and CKD
Briskey, D., Tucker, P. S., Johnson, D. W., & Coombes, J. S. (2016) · Nitric Oxide · doi:10.1016/j.niox.2016.05.002 · Cited by 47
Nitrate uptake and metabolism in human skeletal muscle cell cultures
Srihirun, S., Park, J. W., Teng, R., Sawaengdee, W., Piknova, B., & Schechter, A. N. (2019) · Nitric Oxide · doi:10.1016/j.niox.2019.10.005 · Cited by 47
Self-citationNitric Oxide: A Universal Modulator of Brain Function
Philippu, A. (2016) · Current Medicinal Chemistry · doi:10.2174/0929867323666160627120408 · Cited by 43
Habitual Dietary Nitrate Intake in Highly Trained Athletes
Jonvik, K. L., Nyakayiru, J., van Dijk, J., Wardenaar, F. C., van Loon, L. J. C., & Verdijk, L. B. (2016) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2016-0239 · Cited by 43
Self-citationCould intramuscular storage of dietary nitrate contribute to its ergogenic effect? A mini-review
Nyakayiru, J., van Loon, L. J. C., & Verdijk, L. B. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.03.025 · Cited by 35
Jonvik, K. L., van Dijk, J., Senden, J. M., van Loon, L. J. C., & Verdijk, L. B. (2017) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2017-0293 · Cited by 34
Self-citationMechanism and regulation of ferrous heme-nitric oxide (NO) oxidation in NO synthases
Tejero, J., Hunt, A. P., Santolini, J., Lehnert, N., & Stuehr, D. J. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.007810 · Cited by 33
Totzeck, M., Hendgen-Cotta, U. B., Kelm, M., & Rassaf, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105951 · Cited by 32
Broxterman, R. M., Salle, D. T. L., Zhao, J., Reese, V. R., Richardson, R. S., & Trinity, J. D. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00371.2019 · Cited by 32
Compensatory mechanisms in myoglobin deficient mice preserve NO homeostasis
Park, J. W., Piknova, B., Dey, S., Noguchi, C. T., & Schechter, A. N. (2019) · Nitric Oxide · doi:10.1016/j.niox.2019.06.001 · Cited by 27
Self-citationIs flow-mediated dilation nitric oxide mediated?: A meta-analysis.
Green, D. J., Dawson, E. A., Groenewoud, H. M., et al. (2014) · Radboud Repository (Radboud University) · Cited by 20
Acute Effect of a High Nitrate Diet on Brain Perfusion in Older Adults
Presley, T. D., Morgan, A., Bechtold, E., Clodfelter, W., Dove, R. W., Jennings, J. M., Kraft, R., King, S. B., Laurenti, P. J., Rejeski, W. J., et al. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.10.326 · Cited by 16
The protective role of regular aerobic exercise on vascular function with aging
Craighead, D. H., Freeberg, K. A., & Seals, D. R. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.04.005 · Cited by 16
Self-citationApple, F. S., Hyde, J. E., Ingersoll-Stroubos, A. M., & Theologides, A. (1991) · American Journal of Anatomy · doi:10.1002/aja.1001920311 · Cited by 15
Skeletal Muscle as an Endogenous Nitrate Reservoir
Piknova, B., Park, J. W., Swanson, K. M., & Schechter, A. N. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.10.499 · Cited by 11
Self-citationWoodward, K. A., Santos‐Parker, J. R., Lubieniecki, K. L., Nagy, E., Bryan, N. S., Chonchol, M., Justice, J. N., Seals, D. R., & Rossman, M. J. (2019) · The FASEB Journal · doi:10.1096/fasebj.2019.33.1_supplement.833.13 · Cited by 4
Self-citationNyakayiru, J., Kouw, I. W. K., Cermak, N. M., Senden, J. M., van Loon, L. J. C., & Verdijk, L. B. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.zdg-2487.corr.2017 · Cited by 2
Research works printed but not linked: 1
- 2013, Influence of nitrate supplementation on V˙O2 kinetics and endurance of elite cyclists, Scand J Med Sci Sports, 23, e21
Cited by
Sorted by citations
The Importance of Nitrate Reduction for Oral Health
Rosier, B. T., Takahashi, N., Zaura, E., Krom, B. P., MartÍnez-Espinosa, R. M., van Breda, S. G. J., Marsh, P. D., & Mira, A. (2022) · Journal of Dental Research · doi:10.1177/00220345221080982 · Cited by 175
The oral microbiota and cardiometabolic health: A comprehensive review and emerging insights
Li, Y. H., Zhu, M., Liu, Y., Luo, B., Cui, J., Huang, L., Chen, K., & Liu, Y. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1010368 · Cited by 88
Tanabe, Y., Fujii, N., & Suzuki, K. (2021) · Nutrients · doi:10.3390/nu14010070 · Cited by 77
Emerging Targets and Treatments for Sarcopenia: A Narrative Review
Cacciatore, S., Calvani, R., Esposito, I., Massaro, C., Gava, G., Picca, A., Tosato, M., Marzetti, E., & Landi, F. (2024) · Nutrients · doi:10.3390/nu16193271 · Cited by 75
Calella, P., Cerullo, G., Di Dio, M., Liguori, F., Di Onofrio, V., Gallè, F., & Liguori, G. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1048258 · Cited by 69
Metadata
- Authors
- Jones, A. M., Vanhatalo, A., Seals, D. R., Rossman, M. J., Piknova, B., & Jonvik, K. L.
- Affiliations
- University of Exeter (GB)
- University of Colorado Boulder (US)
- National Institutes of Health (US)
- Maastricht University Medical Centre (NL)
- Corresponding author
- Jones, Andrew M.
- ORCID
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2020-07-29
- Volume
- 53
- Issue
- 2
- Pages
- 280-294
- ISSN
- 0195-9131 (ISSN-L)
- 1530-0315
- OpenAlex
- W3046780524
- Cited by
- 156
- References
- 156
- Citations by year
- 2026: 26 · 2025: 30 · 2024: 30 · 2023: 28 · 2022: 29 · 2021: 13
- FWCI
- 2.23
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- other-oa
- Locations
- Medicine & Science in Sports & Exercise (publishedVersion)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- Research Publications (Maastricht University) (submittedVersion)
- Funders
- National Institute on Aging (R37AG013038, T32AG000279)
- National Heart, Lung, and Blood Institute (R21HL107105)
- National Institute of Diabetes and Digestive and Kidney Diseases (K01DK115524)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Keywords
- dietary nitrate, nitric oxide metabolism, nitrate-nitrite-NO pathway, oral microbiota, nitrite, exercise performance, blood pressure, hypertension, endothelial function, arterial stiffness, beetroot juice, sodium nitrite, nitric oxide synthase, vascular tone
- MeSH terms
- Animals, Biological Availability, Blood Circulation, Cardiovascular Diseases, Endothelium, Vascular, Homeostasis, Humans, Mouth, Nitrates, Nitric Oxide, Risk Factors, Exercise, Muscle, Skeletal, Dietary Supplements, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
