The western diet and lifestyle and diseases of civilization
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Abstract: It is increasingly recognized that certain fundamental changes in diet and lifestyle that occurred after the Neolithic Revolution, and especially after the Industrial Revolution and the Modern Age, are too recent, on an evolutionary time scale, for the human genome to have completely adapted. This mismatch between our ancient physiology and the western diet and lifestyle underlies many so-called diseases of civilization, including coronary heart disease, obesity, hypertension, type 2 diabetes, epithelial cell cancers, autoimmune disease, and osteoporosis, which are rare or virtually absent in hunter–gatherers and other non-westernized populations. It is therefore proposed that the adoption of diet and lifestyle that mimic the beneficial characteristics of the preagricultural environment is an effective strategy to reduce the risk of chronic degenerative diseases. Keywords: Paleolithic, hunter–gatherers, Agricultural Revolution, modern diet, western lifestyle and diseases
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The transition from hunter-gatherer lifestyles to farming societies is associated with a decline in oral health and several additional disease states, including cardiovascular disease, inflammatory bowel diseases, rheumatic diseases, many cancers, and obesity.
“The transition from hunter‐gatherer lifestyles to farming societies is associated with a decline in oral health as well as several additional disease states, including (but not limited to) cardiovascular disease, inflammatory bowel diseases, rheumatic diseases, many cancers, and obesity.”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [257]
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Linking diet to acne metabolomics, inflammation, and comedogenesis: an update
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- Authors
- Carrera-Bastos, P., Fontes, O'Keefe, Lindeberg, & Cordain
- Affiliations
- Lund University (SE)
- Colorado State University (US)
- Venue
- Research Reports in Clinical Cardiology
- Publisher
- Informa UK Limited
- Published
- 2011-03
- Pages
- 15
- ISSN
- 1179-8475 (ISSN-L)
- OpenAlex
- W1991980682
- Cited by
- 342
- References
- 346
- Citations by year
- 2026: 15 · 2025: 23 · 2024: 29 · 2023: 33 · 2022: 28 · 2021: 38 · 2020: 25 · 2019: 24 · 2018: 23 · 2017: 15 · 2016: 27 · 2015: 13 · 2014: 12 · 2013: 22 · 2012: 11
- FWCI
- 15.39
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Research Reports in Clinical Cardiology (publishedVersion, cc-by-nc)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Health Professions › General Health Professions › Indigenous Health and Education
- Life Sciences › Agricultural and Biological Sciences › Food Science › Nutrition, Health, and Society Studies
- Keywords
- Western diet, modern lifestyle, civilization diseases, Paleolithic diet, hunter-gatherers, agricultural revolution, Neolithic transition, Industrial Revolution, modern diet, chronic degenerative diseases, coronary artery disease, obesity, hypertension, type 2 diabetes, autoimmune disease, osteoporosis, evolutionary mismatch
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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