Cited by 160Functional Brain Connectivity StudiesMindfulness and Compassion InterventionsMind wandering and attention

Influence of meditation on anti-correlated networks in the brain

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Josipovic, Zoran, Dinstein, Ilan, Weber, Jochen, Heeger, David J.·2012·Frontiers in Human Neuroscience

Abstract

Human experiences can be broadly divided into those that are external and related to interaction with the environment, and experiences that are internal and self-related. The cerebral cortex appears to be divided into two corresponding systems: an "extrinsic" system composed of brain areas that respond more to external stimuli and tasks and an "intrinsic" system composed of brain areas that respond less to external stimuli and tasks. These two broad brain systems seem to compete with each other, such that their activity levels over time is usually anti-correlated, even when subjects are "at rest" and not performing any task. This study used meditation as an experimental manipulation to test whether this competition (anti-correlation) can be modulated by cognitive strategy. Participants either fixated without meditation (fixation), or engaged in non-dual awareness (NDA) or focused attention (FA) meditations. We computed inter-area correlations ("functional connectivity") between pairs of brain regions within each system, and between the entire extrinsic and intrinsic systems. Anti-correlation between extrinsic vs. intrinsic systems was stronger during FA meditation and weaker during NDA meditation in comparison to fixation (without mediation). However, correlation between areas within each system did not change across conditions. These results suggest that the anti-correlation found between extrinsic and intrinsic systems is not an immutable property of brain organization and that practicing different forms of meditation can modulate this gross functional organization in profoundly different ways.

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Authors
Josipovic, Z., Dinstein, I., Weber, J., & Heeger, D. J.
Affiliations
  • New York University (US)
  • Weizmann Institute of Science (IL)
  • Columbia University (US)
Corresponding author
Josipovic, Zoran
Venue
Frontiers in Human Neuroscience
Published
2012
Volume
5
Pages
183-183
ISSN
1662-5161 (ISSN-L)
OpenAlex
W2163181850
Cited by
160
References
66
Citations by year
2026: 7 · 2025: 8 · 2024: 8 · 2023: 22 · 2022: 10 · 2021: 10 · 2020: 13 · 2019: 6 · 2018: 10 · 2017: 12 · 2016: 12 · 2015: 14 · 2014: 10 · 2013: 12 · 2012: 6
FWCI
6.89
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • Frontiers in Human Neuroscience (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Mind Science Foundation
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
Keywords
meditation, focused attention meditation, functional connectivity, resting-state brain activity, cognitive strategies, brain network organization

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