Influence of meditation on anti-correlated networks in the brain
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Human experiences can be broadly divided into those that are external and related to interaction with the environment, and experiences that are internal and self-related. The cerebral cortex appears to be divided into two corresponding systems: an "extrinsic" system composed of brain areas that respond more to external stimuli and tasks and an "intrinsic" system composed of brain areas that respond less to external stimuli and tasks. These two broad brain systems seem to compete with each other, such that their activity levels over time is usually anti-correlated, even when subjects are "at rest" and not performing any task. This study used meditation as an experimental manipulation to test whether this competition (anti-correlation) can be modulated by cognitive strategy. Participants either fixated without meditation (fixation), or engaged in non-dual awareness (NDA) or focused attention (FA) meditations. We computed inter-area correlations ("functional connectivity") between pairs of brain regions within each system, and between the entire extrinsic and intrinsic systems. Anti-correlation between extrinsic vs. intrinsic systems was stronger during FA meditation and weaker during NDA meditation in comparison to fixation (without mediation). However, correlation between areas within each system did not change across conditions. These results suggest that the anti-correlation found between extrinsic and intrinsic systems is not an immutable property of brain organization and that practicing different forms of meditation can modulate this gross functional organization in profoundly different ways.
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Functional connectivity in the DMN is negatively correlated with other brain neural networks.
“According to the findings, functional connectivity in the DMN is negatively correlated with that of the salience network (Doll et al., 2015), other brain neural networks (Josipovic et al., 2011), and the mindfulness scores of mindful breathing practitioners (Garrison et al., 2015).”
From Frontal Electroencephalography Asymmetry and Desynchronized Functional Connectivity Associated with Long-Term and Short-Term Breathing Training (2026) · cites this paper as Josipovic et al., 2011
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- Authors
- Josipovic, Z., Dinstein, I., Weber, J., & Heeger, D. J.
- Affiliations
- New York University (US)
- Weizmann Institute of Science (IL)
- Columbia University (US)
- Corresponding author
- Josipovic, Zoran
- Venue
- Frontiers in Human Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2012
- Volume
- 5
- Pages
- 183-183
- ISSN
- 1662-5161 (ISSN-L)
- PMC
- PMC3250078
- OpenAlex
- W2163181850
- Cited by
- 160
- References
- 66
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 8 · 2023: 22 · 2022: 10 · 2021: 10 · 2020: 13 · 2019: 6 · 2018: 10 · 2017: 12 · 2016: 12 · 2015: 14 · 2014: 10 · 2013: 12 · 2012: 6
- FWCI
- 6.89
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc
- Locations
- Frontiers in Human Neuroscience (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Mind Science Foundation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
- Keywords
- meditation, focused attention meditation, functional connectivity, resting-state brain activity, cognitive strategies, brain network organization
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