The circadian clock: pacemaker and tumour suppressor

Cancer immunoediting: from immunosurveillance to tumor escape

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Coordination of circadian timing in mammals

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Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

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β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

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AP-1 as a regulator of cell life and death

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Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity

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Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

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Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

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The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

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A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

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Resetting of circadian time in peripheral tissues by glucocorticoid signaling

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STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

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Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

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Extensive and divergent circadian gene expression in liver and heart

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Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

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An h Per2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

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Molecular analysis of mammalian circadian rhythms

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Positional Cloning of the Mouse Circadian Gene

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G Protein Pathways

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The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo

Fu, L., Pelicano, H., Liu, J., Huang, P., & Lee, C. C. (2002) · Cell · doi:10.1016/s0092-8674(02)00961-3 · Cited by 1,268

Time zones: a comparative genetics of circadian clocks

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Rotating night shifts and risk of breast cancer in women participating in the nurses׳ health study

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De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin

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Diurnal Cortisol Rhythm as a Predictor of Breast Cancer Survival

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Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

Rutter, J., Reick, M., Wu, L. C., & McKnight, S. L. (2001) · Science · doi:10.1126/science.1060698 · Cited by 1,059

Circadian rhythms from flies to human

Panda, S., Hogenesch, J. B., & Kay, S. A. (2002) · Nature · doi:10.1038/417329a · Cited by 1,044

Night Shift Work, Light at Night, and Risk of Breast Cancer

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Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

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Light-Induced Resetting of a Mammalian Circadian Clock Is Associated with Rapid Induction of the Transcript

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A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

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Three period Homologs in Mammals: Differential Light Responses in the Suprachiasmatic Circadian Clock and Oscillating Transcripts Outside of Brain

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Melanopsin ( Opn4 ) Requirement for Normal Light-Induced Circadian Phase Shifting

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Regulation of Mammalian Circadian Behavior by Non-rod, Non-cone, Ocular Photoreceptors

Freedman, M. S., Lucas, R. J., Soni, B. G., von Schantz, M., Muñoz, M., David-Gray, Z. K., & Foster, F. (1999) · Science · doi:10.1126/science.284.5413.502 · Cited by 841

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

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Signaling Pathways for PC12 Cell Differentiation: Making the Right Connections

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Circadian oscillation of a mammalian homologue of the Drosophila period gene

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A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms

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Two period Homologs: Circadian Expression and Photic Regulation in the Suprachiasmatic Nuclei

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The basic-helix–loop–helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors

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Circadian Cycling of the Mouse Liver Transcriptome, as Revealed by cDNA Microarray, Is Driven by the Suprachiasmatic Nucleus

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Molecular Dissection of Two Distinct Actions of Melatonin on the Suprachiasmatic Circadian Clock

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RIGUI, a putative mammalian ortholog of the Drosophila period gene.

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A Mutation of the Circadian System in Golden Hamsters

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Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

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On temperature independence in the clock system controlling emergence time in Drosophila

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Target genes of β-catenin–T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

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Suppression of Melatonin Secretion in Some Blind Patients by Exposure to Bright Light

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Role of Melanopsin in Circadian Responses to Light

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Suppression of Myc-Induced Apoptosis in β Cells Exposes Multiple Oncogenic Properties of Myc and Triggers Carcinogenic Progression

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Hypothalamic integration of central and peripheral clocks

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Melanopsin in cells of origin of the retinohypothalamic tract

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Control of cell cycle progression by c-Jun is p53 dependentPreprint

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Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain

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Regulation of the Mammalian Pineal by Non-rod, Non-cone, Ocular Photoreceptors

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A Role for the Segment Polarity Gene shaggy/GSK-3 in the Drosophila Circadian Clock

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Cellular Construction of a Circadian Clock: Period Determination in the Suprachiasmatic Nuclei

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Increased breast cancer risk among women who work predominantly at night

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Restoration of circadian behavioural rhythms by gene transfer in Drosophila

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Neuroendocrine aspects of the response to stress

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Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts

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Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway

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Glucocorticoid hormones inhibit food‐induced phase‐shifting of peripheral circadian oscillators

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Regulation of CLOCK and MOP4 by Nuclear Hormone Receptors in the Vasculature

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Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status.

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Host Circadian Clock as a Control Point in Tumor Progression

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Metabolism and the Control of Circadian Rhythms

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Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses

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Circadian Expression of Clock Genes in Human Oral Mucosa and Skin

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Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei

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Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms

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A role for casein kinase 2α in the Drosophila circadian clock

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Biologic Rhythms in the Immune System

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JunB suppresses cell proliferation by transcriptional activation of p16INK4a expression

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Circadian Programs of Transcriptional Activation, Signaling, and Protein Turnover Revealed by Microarray Analysis of Mammalian Cells

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A DNA Damage–Induced p53 Serine 392 Kinase Complex Contains CK2, hSpt16, and SSRP1

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Multitissue Circadian Expression of Rat periodHomolog (rPer2) mRNA Is Governed by the Mammalian Circadian Clock, the Suprachiasmatic Nucleus in the Brain

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The suprachiasmatic nucleus and the circadian time-keeping system revisited

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The Mammalian UV Response

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Putative Human Blue-Light Photoreceptors hCRY1 and hCRY2 Are Flavoproteins

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Biologic Rhythms in Clinical and Laboratory Medicine

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Involvement of the MAP kinase cascade in resetting of the mammalian circadian clockPreprint

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Output pathways of the mammalian suprachiasmatic nucleus: coding circadian time by transmitter selection and specific targeting

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Fos Family Members Induce Cell Cycle Entry by Activating Cyclin D1

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Effects of Suprachiasmatic Transplants on Circadian Rhythms of Neuroendocrine Function in Golden Hamsters**This work was supported by NIH Grants MH-44132, KO2-MH-00914, and F32-HD-07673. A preliminary report of this research was presented at the 23rd Annual Meeting of the Society for Neuroscience (Neurosci Abstr 19:236.17, 1993).

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Resetting the Biological Clock: Mediation of Nocturnal CREB Phosphorylation via Light, Glutamate, and Nitric Oxide

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A light‐independent oscillatory gene mPer3 in mouse SCN and OVLT

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Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein

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Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release

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Risk of breast cancer in female flight attendants: a population-based study (Iceland)

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