Cited by 2,463Neural dynamics and brain functionVisual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex

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Gray, C M, Singer, W·1989·Proceedings of the National Academy of Sciences

Abstract

In areas 17 and 18 of the cat visual cortex the firing probability of neurons, in response to the presentation of optimally aligned light bars within their receptive field, oscillates with a peak frequency near 40 Hz. The neuronal firing pattern is tightly correlated with the phase and amplitude of an oscillatory local field potential recorded through the same electrode. The amplitude of the local field-potential oscillations are maximal in response to stimuli that match the orientation and direction preference of the local cluster of neurons. Single and multiunit recordings from the dorsal lateral geniculate nucleus of the thalamus showed no evidence of oscillations of the neuronal firing probability in the range of 20-70 Hz. The results demonstrate that local neuronal populations in the visual cortex engage in stimulus-specific synchronous oscillations resulting from an intracortical mechanism. The oscillatory responses may provide a general mechanism by which activity patterns in spatially separate regions of the cortex are temporally coordinated.

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Crossref · 10.1073/pnas.86.5.1698

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Authors
Gray, C. M., & Singer, W.
Affiliations
Max Planck Institute for Brain Research (DE)
Venue
Proceedings of the National Academy of Sciences
Published
1989-03
Volume
86
Issue
5
Pages
1698-1702
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2057213277
Cited by
2,463
References
23
Citations by year
2026: 9 · 2025: 36 · 2024: 34 · 2023: 49 · 2022: 39 · 2021: 61 · 2020: 49 · 2019: 52 · 2018: 47 · 2017: 64 · 2016: 66 · 2015: 82 · 2014: 72 · 2013: 67 · 2012: 61
FWCI
47.48
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
neural oscillations, orientation columns, cat visual cortex, local field potentials, synchronous firing, receptive fields, orientation preference, dorsal lateral geniculate nucleus, area 17, area 18
MeSH terms
Animals, Cats, Neurons, Organ Specificity, Oscillometry, Photic Stimulation, Thalamus, Visual Cortex

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