Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states
Open accessAbstract
The electroencephalogram displays various oscillation patterns during wake and sleep states, but their spatiotemporal distribution is not completely known. Local field potentials (LFPs) and multiunits were recorded simultaneously in the cerebral cortex (areas 5-7) of naturally sleeping and awake cats. Slow-wave sleep (SWS) was characterized by oscillations in the slow (<1 Hz) and delta (1-4 Hz) frequency range. The high-amplitude slow-wave complexes consisted in a positivity of depth LFP, associated with neuronal silence, followed by a sharp LFP negativity, correlated with an increase of firing. This pattern was of remarkable spatiotemporal coherence, because silences and increased firing occurred simultaneously in units recorded within a 7 mm distance in the cortex. During wake and rapid-eye-movement (REM) sleep, single units fired tonically, whereas LFPs displayed low-amplitude fast activities with increased power in fast frequencies (15-75 Hz). In contrast with the widespread synchronization during SWS, fast oscillations during REM and wake periods were synchronized only within neighboring electrodes and small time windows (100-500 msec). This local synchrony occurred in an apparent irregular manner, both spatially and temporally. Brief periods (<1 sec) of fast oscillations were also present during SWS in between slow-wave complexes. During these brief periods, the spatial and temporal coherence, as well as the relation between units and LFPs, was identical to that of fast oscillations of wake or REM sleep. These results show that natural SWS in cats is characterized by slow-wave complexes, synchronized over large cortical territories, interleaved with brief periods of fast oscillations, characterized by local synchrony, and of characteristics similar to that of the sustained fast oscillations of activated states.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the scalp EEG, the negative peak of the slow oscillation coincides with the beginning of the down-to-up state transition, whereas the depolarizing phase of sustained firing correlates with the positive EEG deflection.
“In the scalp EEG, the negative peak of the slow oscillation coincides with the beginning of the down-to-up state transition (281, 993, 1261), whereas the depolarizing phase of sustained firing corre-lates with the positive EEG deflection (33,998,1268).”
From About Sleep's Role in Memory (2013) · cites this paper as [281]
The ‘Slow-wave complexes are preceded by a generalized neuronal silence’ section reports that decreased firing accompanies depth-positive field potentials, followed by increased firing with depth-negative potentials. The introductory passage identifies depth-negative activity as surface-positive and associated with depolarization, supporting the second clause. The paper does not establish that a negative peak in scalp EEG marks the beginning of the down-to-up transition. (LLM, conf=0.83)
Experimental — accuracy not yet measuredInternal brain state can fluctuate even without overt behavioral changes, as in sleep-wake transitions and within sleep stages.
“Internal brain state can fluctuate even in the absence of overt behavioral changes – most notably in the well-characterized transitions between sleep and waking and within different stages of sleep.”
From Waking state: rapid variations modulate neural and behavioral responses (2015) · cites this paper as Destexhe et al., 1999
Falling asleep or moving from slow-wave sleep to REM sleep produces profound changes in brain operation, including spontaneous activity, motor command execution, sensory responses, and the fidelity of internal representations.
“Falling asleep, or moving from slow wave sleep into rapid eye movement sleep, results in profound changes in the operation of the brain (Figure 1), including changes in spontaneous activity, the ability to execute motor commands, responses to sensory stimuli and the fidelity of internal representations of the world”
From Waking state: rapid variations modulate neural and behavioral responses (2015) · cites this paper as Destexhe et al., 1999
Gain modulation mechanisms are robustly engaged by changes in internal state.
“Gain modulation mechanisms are also robustly engaged by changes in internal state32–35.”
From Mechanisms underlying gain modulation in the cortex (2020) · cites this paper as [34]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Numerical Recipes, The Art of Scientific Computing
Press, W. H., Flannery, B. P., Teukolsky, S. A., Vetterling, W. T., & Gould, H. (1987) · American Journal of Physics · doi:10.1119/1.14981 · Cited by 10,032 · see citing works
Numerical recipes: the art of scientific computing
Press, W. H., Flannery, B. P., Teukolsky, S. A., Vetterling, W. T., & CHIPPERFIELD, J. R. (1987) · Analytica Chimica Acta · doi:10.1016/s0003-2670(00)82860-3 · Cited by 4,205 · see citing works
Gray, C. M., König, P., Engel, A. K., & Singer, W. (1989) · Nature · doi:10.1038/338334a0 · Cited by 4,183 · see citing works
Nunez, P. L., & Srinivasan, R. (2006) · doi:10.1093/acprof:oso/9780195050387.001.0001 · Cited by 2,531 · see citing works
Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex
Gray, C. M., & Singer, W. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.5.1698 · Cited by 2,463 · see citing works
Coherent oscillations: A mechanism of feature linking in the visual cortex?
Eckhorn, R., Bauer, R., Jordan, W., Brosch, M., Kruse, W., Munk, M., & Reitboeck, H. J. (1988) · Biological Cybernetics · doi:10.1007/bf00202899 · Cited by 2,329 · see citing works
Electric Fields of the Brain: The Neurophysics of EEG
Nunez, P. L., & Harth, E. M. (1982) · Physics Today · doi:10.1063/1.2915137 · Cited by 2,257 · see citing works
Steriade, M., Nunez, A., & Amzica, F. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-08-03252.1993 · Cited by 1,903 · see citing works
Self-citationCalcium Signaling in Neurons: Molecular Mechanisms and Cellular Consequences
Ghosh, A., & Greenberg, M. E. (1995) · Science · doi:10.1126/science.7716515 · Cited by 1,408 · see citing works
Nucleus basalis and thalamic control of neocortical activity in the freely moving rat
Buzsáki, G., Bickford, R. G., Ponomareff, G., Thal, L. J., Mandel, R. J., & Gage, F. H. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-11-04007.1988 · Cited by 1,039 · see citing works
Coherent 25- to 35-Hz oscillations in the sensorimotor cortex of awake behaving monkeys.
Murthy, V. N., & Fetz, E. E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5670 · Cited by 996 · see citing works
Coherent 40-Hz oscillation characterizes dream state in humans.
Llinás, R., & Ribary, U. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.5.2078 · Cited by 962 · see citing works
Gray, C. M., & McCormick, D. A. (1996) · Science · doi:10.1126/science.274.5284.109 · Cited by 906 · see citing works
Steriade, M., Nunez, A., & Amzica, F. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-08-03266.1993 · Cited by 894 · see citing works
Self-citationTemporal structure in spatially organized neuronal ensembles: a role for interneuronal networks
Buzsáki, G., & Chrobak, J. J. (1995) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(95)80012-3 · Cited by 878 · see citing works
A mechanism for generation of long-range synchronous fast oscillations in the cortex
Traub, R. D., Whittington, M. A., Stanford, I. M., & Jefferys, J. G. R. (1996) · Nature · doi:10.1038/383621a0 · Cited by 701 · see citing works
Cellular basis of EEG slow rhythms: a study of dynamic corticothalamic relationships
Contreras, D., & Steriade, M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00604.1995 · Cited by 700 · see citing works
Self-citationSynchronization of fast (30-40 Hz) spontaneous cortical rhythms during brain activation
Steriade, M., Amzica, F., & Contreras, D. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-01-00392.1996 · Cited by 646 · see citing works
Self-citationSingle unit activity in striate cortex of unrestrained cats
Hubel, D. H. (1959) · The Journal of Physiology · doi:10.1113/jphysiol.1959.sp006238 · Cited by 578 · see citing works
Low-frequency (<1Hz) oscillations in the human sleep electroencephalogram
Achermann, P., & Borbély, A. A. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00186-3 · Cited by 577 · see citing works
TEMPORAL PATTERNS OF DISCHARGE OF PYRAMIDAL TRACT NEURONS DURING SLEEP AND WAKING IN THE MONKEY
Evarts, E. V. (1964) · Journal of Neurophysiology · doi:10.1152/jn.1964.27.2.152 · Cited by 572 · see citing works
Llinás, R. R., Grace, A. A., & Yarom, Y. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.3.897 · Cited by 541 · see citing works
Magnetic field tomography of coherent thalamocortical 40-Hz oscillations in humans.
Ribary, U., Ioannides, A. A., Singh, K. D., Hasson, R., Bolton, J. P., Lado, F. A., Mogilner, A. Y., & Llinas, R. H. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.24.11037 · Cited by 541 · see citing works
Alain Destexhe, A., Contreras, D., & Steriade, M. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.2.999 · Cited by 396 · see citing works
Self-citationGutfreund, Y., Yarom, Y., & Segev, I. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp020611 · Cited by 340 · see citing works
The K-complex: Its slow (<1-Hz) rhythmicity and relation to delta waves
Amzica, F., & Steriade, M. (1997) · Neurology · doi:10.1212/wnl.49.4.952 · Cited by 329 · see citing works
Self-citationSpatial filtering and neocortical dynamics: estimates of EEG coherence
Srinivasan, R., Nunez, P. L., & Silberstein, R. B. (1998) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.686789 · Cited by 326 · see citing works
Synchronization of oscillatory neuronal responses in cat striate cortex: temporal properties
Gray, C. M., Engel, A. K., König, P., & Singer, W. (1992) · Visual Neuroscience · doi:10.1017/s0952523800005071 · Cited by 317 · see citing works
Synchronized sleep oscillations and their paroxysmal developments
Steriade, M., Contreras, D., & Amzica, F. (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90105-8 · Cited by 301 · see citing works
Self-citationSpatial patterns of visual cortical fast EEG during conditioned reflex in a rhesus monkey
Freeman, W. J., & van Dijk, B. W. (1987) · Brain Research · doi:10.1016/0006-8993(87)90933-4 · Cited by 282 · see citing works
Bouyer, J. J., Montaron, M., & Rougeul, A. (1981) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(81)90138-3 · Cited by 256 · see citing works
Steriade, M., Timofeev, I., Dürmüller, N., & Grenier, F. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.1.483 · Cited by 254 · see citing works
Self-citationIntracortical and corticothalamic coherency of fast spontaneous oscillations.
Steriade, M., & Amzica, F. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.6.2533 · Cited by 221 · see citing works
Self-citationDisconnection of intracortical synaptic linkages disrupts synchronization of a slow oscillation
Amzica, F., & Steriade, M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-06-04658.1995 · Cited by 221 · see citing works
Self-citationCoherence analysis of the human sleep electroencephalogram
Achermann, P., & Borbély, A. A. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00692-1 · Cited by 194 · see citing works
Lateral coherence of the electrocorticogram: a new measure of brain synchrony
Bullock, T. H., & McClune, M. C. (1989) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(89)90258-7 · Cited by 167 · see citing works
Temporal fluctuations in coherence of brain waves.
Bullock, T. H., McClune, M. C., Achimowicz, J. Z., Iragui‐Madoz, V., Duckrow, R. B., & Spencer, S. S. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11568 · Cited by 163 · see citing works
Steriade, M., Deschênes, M., & Oakson, G. (1974) · Journal of Neurophysiology · doi:10.1152/jn.1974.37.5.1065 · Cited by 161 · see citing works
Self-citationContreras, D., Alain Destexhe, A., & Steriade, M. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.1.335 · Cited by 153 · see citing works
Self-citationRougeul, A., Bouyer, J. J., Dedet, L., & Debray, O. (1979) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(79)90205-0 · Cited by 149 · see citing works
Intrinsic programmes of growth and survival in developing vertebrate neurons
Davies, A. M. (1994) · Trends in Neurosciences · doi:10.1016/0166-2236(94)90104-x · Cited by 142 · see citing works
The cortical electromicrophysiology of pathological delta waves in the electroencephalogram of cats
Ball, G. J., GLOOR, P., & Schaul, N. (1977) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(77)90258-9 · Cited by 135 · see citing works
Voltage-dependent fast (20–40 Hz) oscillations in long-axoned neocortical neurons
Núñez, Á., Amzica, F., & Steriade, M. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90464-d · Cited by 124 · see citing works
Self-citationLopes, F. H. D. S., van Rotterdam, A., van Leeuwen, W. S., & Tielen, A. M. (1970) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(70)90138-0 · Cited by 97 · see citing works
Rougeul, E., Letalle, A., & Corvisier, J. (1972) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(72)90022-3 · Cited by 87 · see citing works
State-dependent fluctuations of low-frequency rhythms in corticothalamic networks
Contreras, D., & Steriade, M. (1996) · Neuroscience · doi:10.1016/s0306-4522(96)00392-2 · Cited by 54 · see citing works
Self-citationPacemaker-Induced Coherence in Cortical Networks
Destexhe, A., & BABLOYANTZ, A. (1991) · Neural Computation · doi:10.1162/neco.1991.3.2.145 · Cited by 52 · see citing works
Self-citationSingle-unit discharges in isolated cerebral cortex
Frost, J. D., Kellaway, P., & Gol, A. (1966) · Experimental Neurology · doi:10.1016/0014-4886(66)90116-6 · Cited by 26 · see citing works
Flagged first, then by citations
1 of the 49 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- Steriade M, Timofeev I, Grenier F (1999) Intracellular activity of vari- ous neocortical cell-classes during the natural wake-sleep cycle. Soc Neurosci Abstr, in press.
Cited by
Sorted by citations
The magical number 4 in short-term memory: A reconsideration of mental storage capacity
Cowan, N. (2001) · Behavioral and Brain Sciences · doi:10.1017/s0140525x01003922 · Cited by 6,779 · see citing works
The brainweb: phase synchronization and large-scale integration
Varela, F., Lachaux, J.-P., Rodriguez, E., & Martinerie, J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35067550 · Cited by 4,761 · see citing works
Rasch, B., & Born, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00032.2012 · Cited by 2,783 · see citing works
“In the scalp EEG, the negative peak of the slow oscillation coincides with the beginning of the down-to-up state transition (281, 993, 1261), whereas the depolarizing phase of sustained firing correBJÖRN RASCH AND JAN BORN”
BackgroundNeurophysiological and Computational Principles of Cortical Rhythms in Cognition
Wang, X.-J. (2010) · Physiological Reviews · doi:10.1152/physrev.00035.2008 · Cited by 1,939 · see citing works
Long-Range Temporal Correlations and Scaling Behavior in Human Brain Oscillations
Linkenkaer-Hansen, K., Nikouline, V. V., Palva, J. M., & Ilmoniemi, R. J. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-04-01370.2001 · Cited by 1,149 · see citing works
Network abnormalities and interneuron dysfunction in Alzheimer disease
Palop, J. J., & Mucke, L. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2016.141 · Cited by 1,022 · see citing works
Regional Slow Waves and Spindles in Human Sleep
Nir, Y., Staba, R. J., Andrillon, T., Vyazovskiy, V. V., Cirelli, C., Fried, I., & Tononi, G. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.043 · Cited by 924 · see citing works
van Kerkoerle, T., Self, M. W., Dagnino, B., Gariel-Mathis, M.-A., Poort, J., van der Togt, C., & Roelfsema, P. R. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402773111 · Cited by 918 · see citing works
Endogenous electric fields may guide neocortical network activity
Fröhlich, F., & McCormick, D. A. (2010) · Neuron · doi:10.1016/j.neuron.2010.06.005 · Cited by 913 · see citing works
Harris, K. D., & Thiele, A. (2011) · Nature reviews. Neuroscience · doi:10.1038/nrn3084 · Cited by 871 · see citing works
Modelling and analysis of local field potentials for studying the function of cortical circuits
Einevoll, G. T., Kayser, C., Logothetis, N. K., & Panzeri, S. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3599 · Cited by 857 · see citing works
Arousal and Locomotion Make Distinct Contributions to Cortical Activity Patterns and Visual Encoding
Vinck, M., Batista-Brito, R., Knoblich, U., & Cardin, J. A. (2015) · Neuron · doi:10.1016/j.neuron.2015.03.028 · Cited by 819 · see citing works
Waking state: rapid variations modulate neural and behavioral responses
McGinley, M. J., Vinck, M., Reimer, J., Batista-Brito, R., Zagha, E., Cadwell, C. R., Tolias, A. S., Cardin, J. A., & McCormick, D. A. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.012 · Cited by 801 · see citing works
“…in spontaneous activity, the ability to execute motor commands, responses to sensory stimuli and the fidelity of internal representations of the world (Destexhe et al., 1999; Esser et al., 2009; Hennevin et al., 2007; Livingstone and Hubel, 1981; Massimini et al., 2005; Steriade et al., 2001).”
Cortical firing and sleep homeostasis
Vyazovskiy, V. V., Olcese, U., Lazimy, Y. M., Faraguna, U., Esser, S. K., Williams, J. C., Cirelli, C., & Tononi, G. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.024 · Cited by 740 · see citing works
Revealing neuronal function through microelectrode array recordings
Obien, M. E. J., Deligkaris, K., Bullmann, T., Bakkum, D. J., & Frey, U. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00423 · Cited by 705 · see citing works
Linking Spontaneous Activity of Single Cortical Neurons and the Underlying Functional Architecture
Tsodyks, M. V., Kenet, T., Grinvald, A., & Arieli, A. (1999) · Science · doi:10.1126/science.286.5446.1943 · Cited by 702 · see citing works
Hasenstaub, A. R., Shu, Y., Haider, B., Kraushaar, U., Duque, A., & McCormick, D. A. (2005) · Neuron · doi:10.1016/j.neuron.2005.06.016 · Cited by 654 · see citing works
Grouping of spindle activity during slow oscillations in human non-rapid eye movement sleep
Mölle, M., Marshall, L., Gais, S., & Born, J. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-24-10941.2002 · Cited by 617 · see citing works
Dreaming and the brain: from phenomenology to neurophysiology
Nir, Y., & Tononi, G. (2010) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2009.12.001 · Cited by 595 · see citing works
Mölle, M., Bergmann, T. O., Marshall, L., & Born, J. (2011) · Sleep · doi:10.5665/sleep.1290 · Cited by 557 · see citing works
Born, J., Rasch, B., & Gais, S. (2006) · The Neuroscientist · doi:10.1177/1073858406292647 · Cited by 557 · see citing works
Rhythmic and dysrhythmic thalamocortical dynamics: GABA systems and the edge effect
Llinás, R., Urbano, F. J., Leznik, E., Ramírez, R. R., & van Marle, H. J. F. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.04.006 · Cited by 549 · see citing works
Compte, A., Sanchez-Vives, M. V., McCormick, D. A., & Wang, X. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00845.2002 · Cited by 536 · see citing works
Antal, A., Boros, K., Poreisz, C., Chaieb, L., Terney, D., & Paulus, W. (2007) · Brain stimulation · doi:10.1016/j.brs.2007.10.001 · Cited by 509 · see citing works
Isomura, Y., Sirota, A., Özen, S., Montgomery, S., Mizuseki, K., Henze, D. A., & Buzsáki, G. (2006) · Neuron · doi:10.1016/j.neuron.2006.10.023 · Cited by 500 · see citing works
Triggering sleep slow waves by transcranial magnetic stimulation
Massimini, M., Ferrarelli, F., Esser, S. K., Riedner, B. A., Huber, R., Murphy, M., Peterson, M. J., & Tononi, G. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702495104 · Cited by 489 · see citing works
Why do we sleep?11Published on the World Wide Web on 7 November 2000.
Sejnowski, T. J., & Destexhe, A. (2000) · Brain Research · doi:10.1016/s0006-8993(00)03007-9 · Cited by 489 · see citing works
EEG-based drowsiness estimation for safety driving using independent component analysis
Lin, C., Wu, R.-C., Liang, S., Chao, W.-H., Chen, Y., & Jung, T. (2005) · IEEE Transactions on Circuits and Systems I Fundamental Theory and Applications · doi:10.1109/tcsi.2005.857555 · Cited by 472 · see citing works
Intrinsic Coupling Modes: Multiscale Interactions in Ongoing Brain Activity
Engel, A. K., Gerloff, C., Hilgetag, C. C., & Nolte, G. (2013) · Neuron · doi:10.1016/j.neuron.2013.09.038 · Cited by 471 · see citing works
Magill, P. J., Bolam, J. P., & Bevan, M. D. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00281-0 · Cited by 463 · see citing works
Source modeling sleep slow waves
Murphy, M., Riedner, B. A., Huber, R., Massimini, M., Ferrarelli, F., & Tononi, G. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807933106 · Cited by 454 · see citing works
In Vivo Measurement of Cortical Impedance Spectrum in Monkeys: Implications for Signal Propagation
Logothetis, N. K., Kayser, C., & Oeltermann, A. (2007) · Neuron · doi:10.1016/j.neuron.2007.07.027 · Cited by 447 · see citing works
Modeling the Spatial Reach of the LFP
Lindén, H., Tetzlaff, T., Potjans, T. C., Pettersen, K. H., Grün, S., Diesmann, M., & Einevoll, G. T. (2011) · Neuron · doi:10.1016/j.neuron.2011.11.006 · Cited by 443 · see citing works
Rapid Neocortical Dynamics: Cellular and Network Mechanisms
Haider, B., & McCormick, D. A. (2009) · Neuron · doi:10.1016/j.neuron.2009.04.008 · Cited by 441 · see citing works
Sleep function: Toward elucidating an enigma
Krueger, J. M., Frank, M. G., Wisor, J. P., & Roy, S. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.08.005 · Cited by 440 · see citing works
The slow (<1 Hz) rhythm of non-REM sleep: a dialogue between three cardinal oscillators
Crunelli, V., & Hughes, S. W. (2010) · Nature Neuroscience · doi:10.1038/nn.2445 · Cited by 435 · see citing works
Pattern-Specific Associative Long-Term Potentiation Induced by a Sleep Spindle-Related Spike Train
Rosanova, M., & Ulrich, D. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2149-05.2005 · Cited by 413 · see citing works
Temporal coupling of parahippocampal ripples, sleep spindles and slow oscillations in humans
Clemens, Z., Molle, M., Eross, L., Barsi, P., Halasz, P., & Born, J. (2007) · Brain · doi:10.1093/brain/awm146 · Cited by 398 · see citing works
Differential entropy feature for EEG-based vigilance estimation
Shi, L.-C., Jiao, Y.-Y., & Lu, B.-L. (2013) · 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2013.6611075 · Cited by 396 · see citing works
Does the 1 / f Frequency Scaling of Brain Signals Reflect Self-Organized Critical States?
Bédard, C., Kröger, H., & Alain Destexhe, A. (2006) · Physical Review Letters · doi:10.1103/physrevlett.97.118102 · Cited by 391 · see citing works
Sleep and the single neuron: the role of global slow oscillations in individual cell rest
Vyazovskiy, V. V., & Harris, K. D. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3494 · Cited by 362 · see citing works
The restorative effect of naps on perceptual deterioration
Mednick, S. C., Nakayama, K., Cantero, J. L., Atienza, M., Levin, A. A., Pathak, N., & Stickgold, R. (2002) · Nature Neuroscience · doi:10.1038/nn864 · Cited by 360 · see citing works
Are corticothalamic ‘up’ states fragments of wakefulness?
Destexhe, A., Hughes, S. W., Rudolph, M., & Crunelli, V. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.04.006 · Cited by 355 · see citing works
Courtemanche, R., Fujii, N., & Graybiel, A. M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-37-11741.2003 · Cited by 339 · see citing works
Hippocampal Sharp Wave-Ripples Linked to Slow Oscillations in Rat Slow-Wave Sleep
Mölle, M., Yeshenko, O., Marshall, L., Sara, S. J., & Born, J. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00014.2006 · Cited by 337 · see citing works
Dehaene, S., & Changeux, J.-P. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030141 · Cited by 329 · see citing works
Gireesh, E. D., & Plenz, D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800537105 · Cited by 328 · see citing works
Mechanisms underlying gain modulation in the cortex
Ferguson, K. A., & Cardin, J. A. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0253-y · Cited by 327 · see citing works
Global Forebrain Dynamics Predict Rat Behavioral States and Their Transitions
Gervasoni, D., Lin, S., Ribeiro, S. T. G., Soares, E. S., Pantoja, J., & Nicolelis, M. A. L. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3524-04.2004 · Cited by 323 · see citing works
Mölle, M., Eschenko, O., Gais, S., Sara, S. J., & Born, J. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06654.x · Cited by 322 · see citing works
Magill, P. J., Bolam, J. P., & Bevan, M. D. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00820.2000 · Cited by 315 · see citing works
Hippocampal sharp wave bursts coincide with neocortical “up-state” transitions
Battaglia, F. P., Sutherland, G. R., & McNaughton, B. L. (2004) · Learning & Memory · doi:10.1101/lm.73504 · Cited by 310 · see citing works
Ma, Y., Shaik, M. A., Kozberg, M. G., Kim, S. H., Portes, J., Timerman, D., & Hillman, E. M. C. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1525369113 · Cited by 308 · see citing works
Bédard, C., Kröger, H., & Alain Destexhe, A. (2004) · Biophysical Journal · doi:10.1016/s0006-3495(04)74250-2 · Cited by 301 · see citing works
Inhibitory control of acquired motor programmes in the human brain
Hummel, F. C., Andres, F. G., ALTENMÜLLER, E. O., DICHGANS, J., & Gerloff, C. P. (2002) · Brain · doi:10.1093/brain/awf030 · Cited by 287 · see citing works
Computer modelling of epilepsy
Lytton, W. W. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2416 · Cited by 286 · see citing works
The Slow Oscillation in Cortical and Thalamic Networks: Mechanisms and Functions
Neske, G. T. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2015.00088 · Cited by 283 · see citing works
Slow oscillations orchestrating fast oscillations and memory consolidation
Mölle, M., & Born, J. (2011) · Progress in Brain Research · doi:10.1016/b978-0-444-53839-0.00007-7 · Cited by 270 · see citing works
Interaction between neocortical and hippocampal networks via slow oscillations
Sirota, A., & Buzsáki, G. (2005) · Thalamus and Related Systems · doi:10.1017/s1472928807000258 · Cited by 270 · see citing works
Origin of Active States in Local Neocortical Networks during Slow Sleep Oscillation
Chauvette, S., Volgushev, M., & Timofeev, I. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhq009 · Cited by 266 · see citing works
Burst Spiking of a Single Cortical Neuron Modifies Global Brain State
Li, C.-Y. T., Poo, M., & Dan, Y. (2009) · Science · doi:10.1126/science.1169957 · Cited by 257 · see citing works
Neuronal Computations with Stochastic Network States
Alain Destexhe, A., & Contreras, D. (2006) · Science · doi:10.1126/science.1127241 · Cited by 257 · see citing works
Self-citationInhibition recruitment in prefrontal cortex during sleep spindles and gating of hippocampal inputs
Peyrache, A., Battaglia, F. P., & Destexhe, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103612108 · Cited by 254 · see citing works
Mohajerani, M. H., McVea, D. A., Fingas, M., & Murphy, T. H. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.6437-09.2010 · Cited by 246 · see citing works
Cellular and molecular connections between sleep and synaptic plasticity
Benington, J. H., & Frank, M. G. (2003) · Progress in Neurobiology · doi:10.1016/s0301-0082(03)00018-2 · Cited by 244 · see citing works
Fractals in the nervous system: conceptual implications for theoretical neuroscience
Werner, G. (2010) · Frontiers in Physiology · doi:10.3389/fphys.2010.00015 · Cited by 243 · see citing works
Interactions Between Membrane Conductances Underlying Thalamocortical Slow-Wave Oscillations
DESTEXHE, A., & SEJNOWSKI, T. J. (2003) · Physiological Reviews · doi:10.1152/physrev.00012.2003 · Cited by 241 · see citing works
Enhancement of sleep slow waves: underlying mechanisms and practical consequences
Bellesi, M., Riedner, B. A., Garcia-Molina, G. N., Cirelli, C., & Tononi, G. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00208 · Cited by 239 · see citing works
Statistical Method for Detection of Phase-Locking Episodes in Neural Oscillations
Hurtado, J. M., Rubchinsky, L. L., & Sigvardt, K. A. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00853.2003 · Cited by 236 · see citing works
Bagshaw, A. P., Jacobs, J., LeVan, P., Dubeau, F., & Gotman, J. (2008) · Epilepsia · doi:10.1111/j.1528-1167.2008.01784.x · Cited by 230 · see citing works
Okun, M., Naim, A., & Lampl, I. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5062-09.2010 · Cited by 229 · see citing works
Vyazovskiy, V. V., Riedner, B. A., Cirelli, C., & Tononi, G. (2007) · SLEEP · doi:10.1093/sleep/30.12.1631 · Cited by 225 · see citing works
Learning increases human electroencephalographic coherence during subsequent slow sleep oscillations
Mölle, M., Marshall, L., Gais, S., & Born, J. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402820101 · Cited by 222 · see citing works
Neuronal dynamics direct cerebrospinal fluid perfusion and brain clearance
Jiang-Xie, L.-F., Drieu, A., Bhasiin, K., Quintero, D., Smirnov, I., & Kipnis, J. (2024) · Nature · doi:10.1038/s41586-024-07108-6 · Cited by 220 · see citing works
Goldberg, J. A., Rokni, U., Boraud, T., Vaadia, E., & Bergman, H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4848-03.2004 · Cited by 211 · see citing works
Muller, L., Piantoni, G., Koller, D. P., Cash, S. S., Halgren, E., & B, T. J. S. A. (2016) · eLife · doi:10.7554/elife.17267 · Cited by 210 · see citing works
Spatiotemporal dynamics of neocortical excitation and inhibition during human sleep
Peyrache, A., Dehghani, N., Eskandar, E. N., Madsen, J. R., Anderson, W. S., Donoghue, J., Hochberg, L. R., Halgren, E., Cash, S. S., & Alain Destexhe, A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1109895109 · Cited by 210 · see citing works
Mismatch Negativity and Stimulus-Specific Adaptation in Animal Models
Nelken, I., & Ulanovsky, N. (2007) · Journal of Psychophysiology · doi:10.1027/0269-8803.21.34.214 · Cited by 210 · see citing works
Inferring Spike Trains From Local Field Potentials
Rasch, M. J., Gretton, A., Murayama, Y., Maass, W., & Logothetis, N. K. (2007) · Journal of Neurophysiology · doi:10.1152/jn.00919.2007 · Cited by 210 · see citing works
Macroscopic Models of Local Field Potentials and the Apparent 1/f Noise in Brain Activity
Bédard, C., & Alain Destexhe, A. (2009) · Biophysical Journal · doi:10.1016/j.bpj.2008.12.3951 · Cited by 206 · see citing works
The hodology of hallucinations
Ffytche, D. H. (2008) · Cortex · doi:10.1016/j.cortex.2008.04.005 · Cited by 206 · see citing works
Bistability breaks-off deterministic responses to intracortical stimulation during non-REM sleep
Pigorini, A., Sarasso, S., Proserpio, P., Szymanski, C., Arnulfo, G., Casarotto, S., Fecchio, M., Rosanova, M., Mariotti, M., Lo Russo, G., et al. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.02.056 · Cited by 200 · see citing works
Geisler, C. E., Brunel, N., & Wang, X. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00510.2004 · Cited by 193 · see citing works
Removal of Spurious Correlations Between Spikes and Local Field Potentials
Zanos, T. P., Mineault, P., & Pack, C. C. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00642.2010 · Cited by 192 · see citing works
Coding and transmission of information by neural ensembles
Averbeck, B. B., & Lee, D. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.02.006 · Cited by 190 · see citing works
Can Power-Law Scaling and Neuronal Avalanches Arise from Stochastic Dynamics?
Touboul, J. D., & Alain Destexhe, A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008982 · Cited by 190 · see citing works
von der Behrens, W., Bäuerle, P., Kössl, M., & Gaese, B. H. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3475-09.2009 · Cited by 185 · see citing works
Cerebral correlates of delta waves during non-REM sleep revisited
Dang‐Vu, T. T., Desseilles, M., Laureys, S., Degueldre, C., Perrin, F., Phillips, C. L. M., Maquet, P., & Peigneux, P. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.05.028 · Cited by 183 · see citing works
Recovery of consciousness is mediated by a network of discrete metastable activity states
Hudson, A. E., Calderon, D. P., Pfaff, D. W., & Proekt, A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408296111 · Cited by 178 · see citing works
Fontanini, A., Spano, P., & Bower, J. M. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-22-07993.2003 · Cited by 170 · see citing works
NREM and REM Sleep: Complementary Roles in Recovery after Wakefulness
Vyazovskiy, V. V., & Delogu, A. (2014) · The Neuroscientist · doi:10.1177/1073858413518152 · Cited by 169 · see citing works
Berens, P. (2008) · Frontiers in Systems Neuroscience · doi:10.3389/neuro.06.002.2008 · Cited by 162 · see citing works
A novel approach to the detection of synchronisation in EEG based on empirical mode decomposition
Sweeney‐Reed, C. M., & Nasuto, S. J. (2007) · Journal of Computational Neuroscience · doi:10.1007/s10827-007-0020-3 · Cited by 160 · see citing works
Principles of large-scale neural interactions
Vinck, M. A., Uran, C., Spyropoulos, G., Onorato, I., Broggini, A. C., Schneider, M., & Canales‐Johnson, A. (2023) · Neuron · doi:10.1016/j.neuron.2023.03.015 · Cited by 160 · see citing works
Network Synchrony in the Nucleus AccumbensIn Vivo
Goto, Y., & O’Donnell, P. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-12-04498.2001 · Cited by 158 · see citing works
Maladaptive Neural Synchrony in Tinnitus: Origin and Restoration
Eggermont, J. J., & Tass, P. A. (2015) · Frontiers in Neurology · doi:10.3389/fneur.2015.00029 · Cited by 153 · see citing works
Individual Differences in White Matter Diffusion Affect Sleep Oscillations
Piantoni, G., Poil, S., Linkenkaer‐Hansen, K., Verweij, I. M., Ramautar, J. R., Someren, E. J. W. V., & van der Werf, Y. D. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2030-12.2013 · Cited by 152 · see citing works
Universality of Rank-Ordering Distributions in the Arts and Sciences
Martínez‐Mekler, G., Martínez, R. A., del Río, M. B., Mansilla, R., Miramóntes, P., & Cocho, G. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004791 · Cited by 151 · see citing works
Siegel, M., & Peter König, B. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-10-04251.2003 · Cited by 150 · see citing works
Reverberation, storage, and postsynaptic propagation of memories during sleepPreprint
Ribeiro, S. T. G., & Nicolelis, M. A. L. (2004) · Learning & Memory · doi:10.1101/lm.75604 · Cited by 149 · see citing works
- Authors
- Destexhe, A., Contreras, D., & Steriade, M.
- Affiliations
- Université Laval (CA)
- ORCID
- Contreras, Diego
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 1999-06-01
- Volume
- 19
- Issue
- 11
- Pages
- 4595-4608
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6782626
- OpenAlex
- W2146493929
- Cited by
- 573
- References
- 49
- Citations by year
- 2026: 5 · 2025: 9 · 2024: 13 · 2023: 35 · 2022: 20 · 2021: 19 · 2020: 18 · 2019: 29 · 2018: 17 · 2017: 21 · 2016: 25 · 2015: 35 · 2014: 34 · 2013: 24 · 2012: 20
- FWCI
- 7.04
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Medical Research Council Canada
- Medical Research Council
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- local field potentials, single-unit activity, slow-wave sleep, REM sleep, wakefulness, cortical synchronization, spatiotemporal coherence, fast oscillations, cat cerebral cortex, sleep oscillations
- MeSH terms
- Animals, Brain Mapping, Cats, Cortical Synchronization, Electroencephalography, Membrane Potentials, Neurons, Oscillometry, Sleep, Wakefulness
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
