The impact of sugar consumption on stress driven, emotional and addictive behaviors

Jacques, Angela; Chaaya, Nicholas; Beecher, Kate; Ali, Syed Aoun; Belmer, Arnauld; Bartlett, Selena

doi:10.1016/j.neubiorev.2019.05.021

Cited by 271Neurotransmitter Receptor Influence on BehaviorRegulation of Appetite and ObesityEating Disorders and Behaviors

The impact of sugar consumption on stress driven, emotional and addictive behaviors

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Jacques, Angela, Chaaya, Nicholas, Beecher, Kate, Ali, Syed Aoun, Belmer, Arnauld, Bartlett, Selena·2019·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2019.05.021

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Abstract

In 2016 the World Health Organization reported 39% of the world's adult population (over 18 y) was overweight, with western countries such as Australia and the United States of America at 64.5% and 67.9% respectively. Overconsumption of high fat/sugar containing food and beverages contribute to the development of obesity. Neural plasticity that occurs as a result of long term sugar consumption has been shown to reduce impulse control and therefore lower the ability to resist the high fat/sugar foods contributing to the obesity epidemic. There is significant overlap between the neural pathways involved in emotions that guide behavioural responses to survival situations with those regulating overconsumption of highly palatable food. This suggests that having a clearer understanding of the role of stress and emotions in the development of obesity will lead to the development of novel therapeutic strategies. Sucrose consumption activates the mesocorticolimbic system in a manner synonymous with substances of abuse. There is overwhelming evidence to support the hypothesis that sucrose consumption results in pathophysiological consequences such as morphological neuronal changes, altered emotional processing and modified behaviour in rodent and human models. In this comprehensive review, we examined >300 studies investigating the interaction between sugar consumption, stress and emotions. Preclinical and clinical trials investigating highly palatable foods and stress, anxiety, depression and fear are reviewed. Importantly, the synergy between sugar consumption and neurobiology is addressed. This review summarizes the neurochemical changes and neural adaptations ö including changes in the dopaminergic system ö that influence emotion and behaviour following sugar consumption.

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The association between STA and addiction behaviors also exists in the opposite direction.
“Importantly, not only does STA increase addiction behaviors, some authors have suggested this association also exists in the opposite direction [181,182].”
From Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications (2020) · cites this paper as [181]

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The Dictionary of Psychology
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Intake of sucrose-sweetened water induces insulin resistance and exacerbates memory deficits and amyloidosis in a transgenic mouse model of Alzheimer disease
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Repeated social-defeat stress, cocaine or morphine
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Adaptive Increase in D3Dopamine Receptors in the Brain Reward Circuits of Human Cocaine Fatalities
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Amygdala and ventral anterior cingulate activation predicts treatment response to cognitive behaviour therapy for post-traumatic stress disorder
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Hunger-Driven Motivational State Competition
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The Association Between Habitual Diet Quality and the Common Mental Disorders in Community-Dwelling Adults
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Artificial sweeteners—do they bear a carcinogenic risk?
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Salt, sugar, fat: how the food giants hooked us
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Assessment and Treatment of Anxiety Disorders in Children and Adolescents
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Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state
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Neurobiology of substance P and the NK1 receptor.
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A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine
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A Role for the Polyol Pathway in the Early Neuroretinal Apoptosis and Glial Changes Induced by Diabetes in the Rat
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Acetylcholine–dopamine balance hypothesis in the striatum: An update
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Neuronal circuits that regulate feeding behavior and metabolism
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Hormones and the hippocampus
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Fast-food and commercial baked goods consumption and the risk of depression
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Seeking a Spotless Mind: Extinction, Deconsolidation, and Erasure of Fear Memory
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“This reduction in fear is similar to basic theories surrounding exposure therapy, whereby excessive exposure to fear-inducing stimuli (via mental imagery, for example) results in a reduction in fear-related symptoms (Maren, 2011; Milad and Quirk, 2012).”
Background
Orexin-induced food intake involves neuropeptide Y pathway
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Cannabis Addiction and the Brain: a Review
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Opiate-like effects of sugar on gene expression in reward areas of the rat brain
Spangler, R., Wittkowski, K. M., Goddard, N. L., Avena, N. M., Hoebel, B. G., & LEIBOWITZ, S. F. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.02.013 · Cited by 255 · see citing works
The neural networks of inhibitory control in posttraumatic stress disorder
Falconer, E., Bryant, R., Felmingham, K. L., Kemp, A. H., Gordon, E., Peduto, A., Olivieri, G., & Williams, L. M. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0839 · Cited by 249 · see citing works
Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine.
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Mesolimbic Dopamine D3 Receptors and Use of Antipsychotics in Patients With Schizophrenia
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Neural responses to visual food cues according to weight status: a systematic review of functional magnetic resonance imaging studies
Pursey, K. M., Stanwell, P., Callister, R. J., Brain, K., Collins, C. E., & Burrows, T. L. (2014) · Frontiers in Nutrition · doi:10.3389/fnut.2014.00007 · Cited by 239 · see citing works
Sugar intake from sweet food and beverages, common mental disorder and depression: prospective findings from the Whitehall II study
Knüppel, A., Shipley, M. J., Llewellyn, C. H., & Brunner, E. J. (2017) · Scientific Reports · doi:10.1038/s41598-017-05649-7 · Cited by 236 · see citing works
Short exposure to a diet rich in both fat and sugar or sugar alone impairs place, but not object recognition memory in rats
Beilharz, J. E., Maniam, J., & Morris, M. J. (2014) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2013.11.016 · Cited by 234 · see citing works
Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion
Kyriazis, G. A., Soundarapandian, M. M., & Tyrberg, B. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115183109 · Cited by 233 · see citing works
Pleasurable behaviors reduce stress via brain reward pathways
Ulrich-Lai, Y. M., Christiansen, A. M., Ostrander, M. M., Jones, A. A., Jones, K. R., Choi, D. C., Krause, E. G., Evanson, N. K., Furay, A. R., Davis, J. F., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007740107 · Cited by 231 · see citing works
The Role of Glutamate in Anxiety and Related Disorders
Cortese, B. M., & Phan, K. L. (2005) · CNS Spectrums · doi:10.1017/s1092852900010427 · Cited by 231 · see citing works
An Evaluation of Mobile Health Application Tools
Sama, P. R., Eapen, Z. J., Weinfurt, K. P., Shah, B. R., & Schulman, K. A. (2014) · JMIR mHealth and uHealth · doi:10.2196/mhealth.3088 · Cited by 230 · see citing works
Motivation for palatable food despite consequences in an animal model of binge eating
Oswald, K. D., Murdaugh, D. L., King, V. L., & Boggiano, M. M. (2010) · International Journal of Eating Disorders · doi:10.1002/eat.20808 · Cited by 220 · see citing works
Effects of sucrose and high fructose corn syrup consumption on spatial memory function and hippocampal neuroinflammation in adolescent rats: Adolescent Sugar Intake Impairs Spatial Memory
Hsu, T. M., Konanur, V. R., Taing, L., Usui, R., Kayser, B. D., Goran, M. I., & Kanoski, S. E. (2015) · Hippocampus · doi:10.1002/hipo.22368 · Cited by 217 · see citing works
Rapid strengthening of thalamo-amygdala synapses mediates cue–reward learning
Tye, K. M., Stuber, G. D., de Ridder, B., Bonci, A., & Janak, P. H. (2008) · Nature · doi:10.1038/nature06963 · Cited by 216 · see citing works
Sugar-dependent rats show enhanced responding for sugar after abstinence: Evidence of a sugar deprivation effect
Avena, N. M., Long, K. A., & Hoebel, B. G. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.12.016 · Cited by 215 · see citing works
Separate circuitries encode the hedonic and nutritional values of sugar
Téllez, L. A., Han, W., Zhang, X., Ferreira, T. L., Pérez-Martínez, I. O., Shammah‐Lagnado, S. J., van den Pol, A. N., & de Araújo, I. E. (2016) · Nature Neuroscience · doi:10.1038/nn.4224 · Cited by 215 · see citing works
Drug Addiction, Relapse, and the Amygdala
See, R. E., Fuchs, R. A., Ledford, C. C., & McLaughlin, J. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07089.x · Cited by 212 · see citing works
Role of addiction and stress neurobiology on food intake and obesity
Sinha, R. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2017.05.001 · Cited by 211 · see citing works
Food addiction: true or false?
Corsica, J. A., & Pelchat, M. L. (2010) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e328336528d · Cited by 209 · see citing works
Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation
Davidson, T. L., Chan, K., Jarrard, L. E., Kanoski, S. E., Clegg, D. J., & Benoit, S. C. (2008) · Hippocampus · doi:10.1002/hipo.20499 · Cited by 203 · see citing works
Molecular mechanisms in the regulation of adult neurogenesis during stress
Egeland, M., Zunszain, P. A., & Pariante, C. M. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3855 · Cited by 203 · see citing works
Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response
Avena, N. M., Rada, P. V., Moise, N., & Hoebel, B. G. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.12.037 · Cited by 195 · see citing works
Evidence for defective mesolimbic dopamine exocytosis in obesity‐prone rats
Geiger, B. M., Behr, G. G., Frank, L. E., Caldera-Siu, A. D., Beinfeld, M. C., Kokkotou, E. G., & Pothos, E. N. (2008) · The FASEB Journal · doi:10.1096/fj.08-110759 · Cited by 194 · see citing works
Differential effects of central fructose and glucose on hypothalamic malonyl–CoA and food intake
Cha, S. H., Wolfgang, M. J., Tokutake, Y., Chohnan, S., & Lane, M. D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809255105 · Cited by 191 · see citing works
The role of reward circuitry and food addiction in the obesity epidemic: An update
Leigh, S.-J., & Morris, M. J. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2016.12.013 · Cited by 191 · see citing works
International variations in the outcome of schizophrenia and the prevalence of depression in relation to national dietary practices: An ecological analysis
Peet, M. (2004) · The British Journal of Psychiatry · doi:10.1192/bjp.184.5.404 · Cited by 188 · see citing works
A short history of beverages and how our body treats them
Wolf, A., Bray, G. A., & Popkin, B. M. (2007) · Obesity Reviews · doi:10.1111/j.1467-789x.2007.00389.x · Cited by 187 · see citing works
Adolescent life events as predictors of adult depression
Pine, D. S., Cohen, P., Johnson, J. G., & Brook, J. S. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00331-1 · Cited by 184 · see citing works
The additive effect of neurotransmitter genes in pathological gambling
Comings, D. E., Gade‐Andavolu, R., Gonzalez, N., Wu, S., Muhleman, D. R., Chen, C., Koh, P. K., Hagman, K. D. F., Blake, H., Dietz, G., et al. (2001) · Clinical Genetics · doi:10.1034/j.1399-0004.2001.600204.x · Cited by 183 · see citing works
Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences
Aringhieri, S., Carli, M., Kolachalam, S., Verdesca, V., Cinì, E., Rossi, M., McCormick, P., Corsini, G., Maggio, R., & Scarselli, M. (2018) · Pharmacology and Therapeutics · doi:10.1016/j.pharmthera.2018.06.012 · Cited by 182 · see citing works
Increased Ethanol Self-Administration after a Period of Imposed Ethanol Deprivation in Rats Trained in a Limited Access Paradigm
Heyser, C. J., Schulteis, G., & Koob, G. F. (1997) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1997.tb03840.x · Cited by 181 · see citing works
The induction of behavioural sensitization is associated with cocaine‐induced structural plasticity in the core (but not shell) of the nucleus accumbens
Li, Y., Acerbo, M. J., & Robinson, T. E. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03612.x · Cited by 180 · see citing works
Optogenetic Excitation of Central Amygdala Amplifies and Narrows Incentive Motivation to Pursue One Reward Above Another
Robinson, M. J. F., Warlow, S. M., & Berridge, K. C. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.2013-14.2014 · Cited by 180 · see citing works
Consumption of Soft Drinks and Hyperactivity, Mental Distress, and Conduct Problems Among Adolescents in Oslo, Norway
Lien, L., Lien, N., Heyerdahl, S., Thoresen, M., & Bjertness, E. (2006) · American Journal of Public Health · doi:10.2105/ajph.2004.059477 · Cited by 179 · see citing works
Accumbens dopamine-acetylcholine balance in approach and avoidance
Hoebel, B. G., Avena, N. M., & Rada, P. V. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.10.014 · Cited by 178 · see citing works
Opioid system and human emotions
Nummenmaa, L., & Tuominen, L. (2018) · British Journal of Pharmacology · doi:10.1111/bph.13812 · Cited by 178 · see citing works
Eating disorders, obesity and addiction
Wilson, G. T. (2010) · European Eating Disorders Review · doi:10.1002/erv.1048 · Cited by 171 · see citing works
Highly palatable diet consumption increases protein oxidation in rat frontal cortex and anxiety-like behavior
de Souza, C. G., Moreira, J. D., Siqueira, I. R., Pereira, A. G., Rieger, D. K., Souza, D. O., Souza, T. M. E., Portela, L. V., & Perry, M. L. S. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.05.001 · Cited by 168 · see citing works
mHealth (Mobile Health)—Using Apps for Health and Wellness
Handel, M. J. (2011) · EXPLORE · doi:10.1016/j.explore.2011.04.011 · Cited by 168 · see citing works
Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry
Wang, G.-J., Yang, J., Volkow, N. D., Telang, F., Ma, Y., Zhu, W., Wong, C. T., Tomasi, D., Thanos, P. K., & Fowler, J. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601977103 · Cited by 168 · see citing works
The Influence of ΔFosB in the Nucleus Accumbens on Natural Reward-Related Behavior
Wallace, D. L., Vialou, V., Rios, L., Carle-Florence, T. L., Chakravarty, S., Kumar, A., Graham, D. L., Green, T. A., Kirk, A., Iñiguez, S. D., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1531-08.2008 · Cited by 166 · see citing works
Palatability Can Drive Feeding Independent of AgRP Neurons
Denis, R. G. P., Joly-Amado, A., Webber, E., Langlet, F., Schaeffer, M., Padilla, S. L., Cansell, C., Dehouck, B., Castel, J., Delbès, A.-S., et al. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.07.011 · Cited by 164 · see citing works
Lower growth hormone and higher cortisol are associated with greater visceral adiposity, intramyocellular lipids, and insulin resistance in overweight girls
Misra, M., Bredella, M. A., Tsai, P., Mendes, N., Miller, K. K., & Klibanski, A. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00052.2008 · Cited by 163 · see citing works
Food addiction A common neurobiological mechanism with drug abuse
Wang, G. (2017) · Frontiers in bioscience · doi:10.2741/4618 · Cited by 163 · see citing works
An update on contextual fear memory mechanisms: Transition between Amygdala and Hippocampus
Chaaya, N., Battle, A. R., & Johnson, L. R. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.05.013 · Cited by 163 · see citing works
Influence of topiramate in the regulation of energy balance
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Sweetened beverages, coffee, and tea and depression risk among older US adults
Guo, X., Park, Y., Freedman, N. D., Sinha, R., Hollenbeck, A. R., Blair, A., & Chen, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094715 · Cited by 161 · see citing works
Natural Addiction
Hoebel, B. G., Avena, N. M., Bocarsly, M. E., & Rada, P. V. (2009) · Journal of Addiction Medicine · doi:10.1097/adm.0b013e31819aa621 · Cited by 159 · see citing works
Feelings about food: the ventral tegmental area in food reward and emotional eating
Meye, F. J., & Adan, R. A. H. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.11.003 · Cited by 156 · see citing works
Hypothalamic melanin concentrating hormone neurons communicate the nutrient value of sugar
Domingos, A. I., Sordillo, A., Dietrich, M. O., Liu, Z.-W., Téllez, L. A., Vaynshteyn, J., Ferreira, J. G. P., Ekstrand, M. I., Horváth, T. L., de Araújo, I. E., et al. (2013) · eLife · doi:10.7554/elife.01462 · Cited by 154 · see citing works
Endogenous opioid systems
Benarroch, E. E. (2012) · Neurology · doi:10.1212/wnl.0b013e3182662098 · Cited by 152 · see citing works
Molecular Mechanisms of Appetite Regulation
Yu, J. H., & Kim, M. (2012) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2012.36.6.391 · Cited by 148 · see citing works
The hypothalamic arcuate nucleus and the control of peripheral substrates
Joly‐Amado, A., Cansell, C., Denis, R., Delbès, A.-S., Castel, J., Martinez, S., & Luquet, S. H. (2014) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2014.03.003 · Cited by 147 · see citing works
The plausibility of sugar addiction and its role in obesity and eating disorders
Benton, D. (2010) · Clinical Nutrition · doi:10.1016/j.clnu.2009.12.001 · Cited by 144 · cited 3× · see citing works
“…with a choice between a saccharin solution and intravenous cocaine demonstrated the reward provided by the sweetness surpassed the desire for cocaine (Lenoir et al., 2007); an intense debate remains as to whether sugar is in fact addictive (Benton, 2010; Corsica and Pelchat, 2010; Wilson, 2010).”
Background
Sugar addiction
Ahmed, S. H., Guillem, K., & Vandaele, Y. (2013) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328361c8b8 · Cited by 144 · see citing works
Exposure to early life trauma is associated with adult obesity
Gunstad, J., Paul, R. H., Spitznagel, M. B., Cohen, R. A., Williams, L. M., Kohn, M. R., & Gordon, E. (2006) · Psychiatry Research · doi:10.1016/j.psychres.2005.11.007 · Cited by 144 · see citing works
Repeated sucrose access influences dopamine D2 receptor density in the striatum
Bello, N. T., Lucas, L. R., & Hajnal, A. (2002) · Neuroreport · doi:10.1097/00001756-200208270-00017 · Cited by 144 · see citing works
Pharmacological management of appetite expression in obesity
Halford, J. C. G., Boyland, E. J., Blundell, J. E., Kirkham, T. C., & Harrold, J. A. (2010) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2010.19 · Cited by 142 · see citing works
Effects of nicotine and mecamylamine-induced withdrawal on extracellular dopamine and acetylcholine in the rat nucleus accumbens
Rada, P., Jensen, K., & Hoebel, B. (2001) · Psychopharmacology · doi:10.1007/s002130100781 · Cited by 141 · see citing works
CART in the regulation of appetite and energy homeostasis
Lau, J., & Herzog, H. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00313 · Cited by 138 · see citing works
Opioids as agents of reward-related feeding: a consideration of the evidence
Levine, A. S., & Billington, C. J. (2004) · Physiology & Behavior · doi:10.1016/j.physbeh.2004.04.032 · Cited by 138 · see citing works
Rostral anterior cingulate volume predicts treatment response to cognitive-behavioural therapy for posttraumatic stress disorder
Bryant, R. A., Felmingham, K. L., Whitford, T. J., Kemp, A. H., Hughes, G., Peduto, A. S., & Williams, L. M. (2008) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0816 · Cited by 138 · see citing works
Sugar addiction: the state of the science
Westwater, M. L., Fletcher, P. C., & Ziauddeen, H. (2016) · Zeitschrift für Ernährungswissenschaft · doi:10.1007/s00394-016-1229-6 · Cited by 138 · see citing works
Multiple brain sites sensitive to feeding stimulation by opioid agonists: A cannula-mapping study
Stanley, B. G., Lanthier, D., & LEIBOWITZ, S. F. (1988) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(88)90391-7 · Cited by 136 · see citing works
The Neurobiological Mechanisms of Generalized Anxiety Disorder and Chronic Stress
Patriquin, M. A., & Mathew, S. J. (2017) · Chronic Stress · doi:10.1177/2470547017703993 · Cited by 135 · see citing works
The Neurobiology of Anxiety Disorders: Brain Imaging, Genetics, and Psychoneuroendocrinology
Martin, E. I., Ressler, K. J., Binder, E. B., & Nemeroff, C. (2009) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2009.05.004 · Cited by 132 · see citing works
Neural systems for executive and emotional processing are modulated by symptoms of posttraumatic stress disorder in Iraq War veterans
Morey, R. A., Petty, C. M., Cooper, D. A., LaBar, K. S., & McCarthy, G. (2008) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2007.07.007 · Cited by 131 · see citing works
A spoonful of sugar: feedback signals of energy stores and corticosterone regulate responses to chronic stress
Dallman, M. F., Akana, S. F., Laugero, K. D., Gómez-Oliver, F., Manalo, S. L., Bell, M. E., & Bhatnagar, S. (2003) · Physiology & Behavior · doi:10.1016/s0031-9384(03)00100-8 · Cited by 129 · see citing works
Excessive sugar consumption may be a difficult habit to break: a view from the brain and body
Tryon, M. S., Stanhope, K. L., Epel, E. S., Mason, A. E., Brown, R., Medici, V., Havel, P. J., & Laugero, K. D. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-4353 · Cited by 128 · see citing works

Flagged first, then by citations

9 of the 398 references couldn’t be matched to a known paper.

Sorted by citations

Does COVID-19 change dietary habits and lifestyle behaviours in Kuwait: a community-based cross-sectional study
Husain, W., & Ashkanani, F. (2020) · Environmental Health and Preventive Medicine · doi:10.1186/s12199-020-00901-5 · Cited by 233 · see citing works
New Insights and Potential Therapeutic Interventions in Metabolic Diseases
Clemente‐Suárez, V. J., Martín-Rodríguez, A., Redondo-Flórez, L., López-Mora, C., Sepulveda, R. A. Y., & Tornero-Aguilera, J. F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310672 · Cited by 166 · see citing works
Western Diet: Implications for Brain Function and Behavior
López-Taboada, I., González‐Pardo, H., & Conejo, N. M. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.564413 · Cited by 141 · see citing works
Understanding dental caries as a non-communicable and behavioral disease: Management implications
Giacaman, R., Fernández, C. E., Muñoz-Sandoval, C., León, S., García-Manríquez, N., Echeverría, C., Valdés, S., Castro, R. J., & Gambetta-Tessini, K. (2022) · Frontiers in Oral Health · doi:10.3389/froh.2022.764479 · Cited by 141 · see citing works
The Impact of Free Sugar on Human Health—A Narrative Review
Gillespie, K. M., Kemps, E., White, M. J., & Bartlett, S. E. (2023) · Nutrients · doi:10.3390/nu15040889 · Cited by 123 · see citing works
A High-Sugar Diet Consumption, Metabolism and Health Impacts with a Focus on the Development of Substance Use Disorder: A Narrative Review
Witek, K., Wydra, K., & Filip, M. (2022) · Nutrients · doi:10.3390/nu14142940 · Cited by 128 · see citing works
The neuroplastic brain: current breakthroughs and emerging frontiers
Gazerani, P. (2025) · Brain Research · doi:10.1016/j.brainres.2025.149643 · Cited by 132 · see citing works
Quality Parameters and Consumer Acceptance of Jelly Candies Based on Pomegranate Juice “Mollar de Elche”
Cano‐Lamadrid, M., Calín‐Sánchez, Á., Clemente-Villalba, J., Hernández, F., Carbonell-Barrachina, Á. A., Sendra, E., & Wojdyło, A. (2020) · Foods · doi:10.3390/foods9040516 · Cited by 83 · see citing works
Development and characterization of healthy gummy jellies containing natural fruits
Teixeira‐Lemos, E., Almeida, A. R., Vouga, B., Morais, C., Correia, I., Pereira, P., & Guiné, R. P. F. (2021) · Open Agriculture · doi:10.1515/opag-2021-0029 · Cited by 83 · see citing works
Shared biological mechanisms of depression and obesity: focus on adipokines and lipokines
Fu, X., Wang, Y., Zhao, F., Cui, R., Xie, W., Liu, Q., & Yang, W. (2023) · Aging · doi:10.18632/aging.204847 · Cited by 84 · see citing works
The relationship between body roundness index and depression: A cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) 2011–2018
Zhang, L., Yin, J., Sun, H., Dong, W., Liu, Z., Yang, J., & Liu, Y. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.05.153 · Cited by 73 · see citing works
Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications
Wiss, D. A., Avena, N., & Gold, M. (2020) · Nutrients · doi:10.3390/nu12113521 · Cited by 66 · see citing works
Satiety from healthier and functional foods
Munekata, P. E. S., Pérez‐Álvarez, J. Á., Pateiro, M., Viuda‐Martos, M., Fernández‐López, J., & Lorenzo, J. M. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.05.025 · Cited by 64 · see citing works
Rethinking sugar reduction in processed foods
Deliza, R., Lima, M., & Ares, G. (2021) · Current Opinion in Food Science · doi:10.1016/j.cofs.2021.01.010 · Cited by 56 · see citing works
Low Dose of Sucralose Alter Gut Microbiome in Mice
Zheng, Z., Xiao, Y., Ma, L., Lyu, W., Peng, H., Wang, X., Ren, Y., & Li, J. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.848392 · Cited by 53 · see citing works
Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood
Beecher, K., Cooper, I. A., Wang, J., Walters, S. B., Chehrehasa, F., Bartlett, S. E., & Belmer, A. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.670430 · Cited by 51 · see citing works
The Impact of Parental Preconception Nutrition, Body Weight, and Exercise Habits on Offspring Health Outcomes: A Narrative Review
Jahan-Mihan, A., Leftwich, J., Berg, K., Labyak, C. A., Nodarse, R. R., Allen, S., & Griggs, J. J. (2024) · Nutrients · doi:10.3390/nu16244276 · Cited by 40 · see citing works
Sleep loss and addiction
López-Muciño, L. A., García‐García, F., Cueto‐Escobedo, J., Acosta-Hernández, M. E., Venebra-Muñoz, A., & Rodríguez‐Alba, J. C. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104832 · Cited by 39 · see citing works
Early life high fructose impairs microglial phagocytosis and neurodevelopment
Wang, Z., Lipshutz, A. B., de la Torre, C. M., Trzeciak, A. J., Liu, Z.-L., Miranda, I. C., Lazarov, T., Codo, A. C., Romero-Pichardo, J. E., Nair, A., et al. (2025) · Nature · doi:10.1038/s41586-025-09098-5 · Cited by 45 · see citing works
Obesogenic diets induce anxiety in rodents: A systematic review and meta‐analysis
Clark, T. D., Crean, A. J., & Senior, A. M. (2021) · Obesity Reviews · doi:10.1111/obr.13399 · Cited by 35 · see citing works
Free Amino Acid Content in Human Milk Is Associated with Infant Gender and Weight Gain during the First Four Months of Lactation
Baldeon, M. E., Zertuche, F., Flores, N., & Fornasini, M. (2019) · Nutrients · doi:10.3390/nu11092239 · Cited by 34 · see citing works
Screen time-based sedentary behaviour, eating regulation and weight status of university students during the COVID-19 lockdown
Tan, S. T., Tan, S. S., & Tan, C. X. (2021) · Nutrition & Food Science · doi:10.1108/nfs-05-2021-0156 · Cited by 34 · see citing works
Key Nutrients for Optimal Blood Glucose Control and Mental Health in Individuals with Diabetes: A Review of the Evidence
Basiri, R., Seidu, B., & Cheskin, L. J. (2023) · Nutrients · doi:10.3390/nu15183929 · Cited by 34 · see citing works
Sugars and Sweet Taste: Addictive or Rewarding?
Greenberg, D., & Peter, J. V. S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18189791 · Cited by 30 · see citing works
High-carbohydrate and fat diet consumption causes metabolic deterioration, neuronal damage, and loss of recognition memory in rats
Fuentes‐Medel, E., Venegas, B., Muñoz‐Arenas, G., Morán, C., Vázquez‐Roque, R. A., Flores, G., Treviño, S., Díaz, A., & Guevara, J. (2023) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2023.102237 · Cited by 28 · see citing works
Association of sugar consumption with risk of depression and anxiety: a systematic review and meta-analysis
Xiong, J., Wang, L., Huang, H., Xiong, S., Zhang, S., Fu, Q., Tang, R., & Zhang, Q. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1472612 · Cited by 33 · see citing works
Anxiety and Food Addiction in Men and Women: Results From the Longitudinal LIFE-Adult-Study
Hussenoeder, F. S., Pabst, A., Conrad, I., Löbner, M., Engel, C., Zeynalova, S., Reyes, N., Glaesmer, H., Hinz, A., Witte, A. V., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.914358 · Cited by 26 · see citing works
The Association of Soft Drink Consumption and the 24-Hour Movement Guidelines with Suicidality among Adolescents of the United States
Liu, B.-P., Jia, C.-X., & Li, S. (2022) · Nutrients · doi:10.3390/nu14091870 · Cited by 25 · see citing works
Net gain and loss: influence of natural rewards and drugs of abuse on perineuronal nets
Brown, T. E., & Sorg, B. A. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01337-x · Cited by 25 · see citing works
Fructose and uric acid as drivers of a hyperactive foraging response: A clue to behavioral disorders associated with impulsivity or mania?
Johnson, R. J., Wilson, W. L., Bland, S. T., & Lanaspa, M. A. (2020) · Evolution and Human Behavior · doi:10.1016/j.evolhumbehav.2020.09.006 · Cited by 27 · see citing works
Dietary fructose: from uric acid to a metabolic switch in pediatric metabolic dysfunction-associated steatotic liver disease
Faienza, M. F., Cognetti, E., Farella, I., Antonioli, A., Tini, S., Antoniotti, V., & Prodam, F. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2024.2392150 · Cited by 24 · see citing works
Synthetic Supramolecular Host for D‐(−)‐Ribose: Ratiometric Fluorescence Response via Multivalent Lectin‐Carbohydrate Interactions
Fernandes, R. S., & Dey, N. (2022) · ChemBioChem · doi:10.1002/cbic.202200044 · Cited by 23 · see citing works
Impact of the COVID-19 Pandemic on Changes in Consumer Purchasing Behavior in the Food Market with a Focus on Meat and Meat Products—A Comprehensive Literature Review
Żurek, J., & Rudy, M. (2024) · Foods · doi:10.3390/foods13060933 · Cited by 32 · see citing works
Sugar reduction in products targeted at children: Why are we not there yet?
Velázquez, A. L., Vidal, L., Varela, P., & Ares, G. (2021) · Journal of Sensory Studies · doi:10.1111/joss.12666 · Cited by 23 · see citing works
Decoding the Role of Gut-Microbiome in the Food Addiction Paradigm
Novelle, M. G. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18136825 · Cited by 23 · see citing works
Diet Quality and Measures of Sarcopenia in Developing Economies: A Systematic Review
Ramadas, A., Law, H. H., Krishnamoorthy, R., Ku, J. W. S., Mohanty, P., Lim, M. Z. C., & Shyam, S. (2022) · Nutrients · doi:10.3390/nu14040868 · Cited by 22 · see citing works
Curiosity for information predicts wellbeing mediated by loneliness during COVID-19 pandemic
Vermeer, A. B. L., Muth, A.-K., Terenzi, D., & Park, S. Q. (2022) · Scientific Reports · doi:10.1038/s41598-022-11924-z · Cited by 26 · see citing works
Application of Theory of Planned Behavior (TPB) on fast-food consumption preferences among generation Z in Dhaka City, Bangladesh: an empirical study
Shetu, S. N. (2022) · Journal of Foodservice Business Research · doi:10.1080/15378020.2022.2086420 · Cited by 22 · see citing works
Sucrose Consumption Alters Serotonin/Glutamate Co-localisation Within the Prefrontal Cortex and Hippocampus of Mice
Beecher, K., Wang, J., Jacques, A., Chaaya, N., Chehrehasa, F., Belmer, A., & Bartlett, S. E. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.678267 · Cited by 22 · see citing works
History of child maltreatment and excessive dietary and screen time behaviors in young adults: Results from a nationally representative study
Cammack, A. L., Gazmararian, J. A., & Suglia, S. F. (2020) · Preventive Medicine · doi:10.1016/j.ypmed.2020.106176 · Cited by 21 · see citing works
Development of a functional prebiotic strawberry preparation by in situ enzymatic conversion of sucrose into fructo-oligosaccharides
Gonçalves, D. A., Alves, V. D., Teixeira, J. A., & Nobre, C. (2023) · Food Research International · doi:10.1016/j.foodres.2023.112671 · Cited by 21 · see citing works
Consumer Motives for Choosing Fruit and Cereal Bars—Differences Due to Consumer Lifestyles, Attitudes toward the Product, and Expectations
Kosicka-Gębska, M., Jeżewska-Zychowicz, M., Gębski, J., Sajdakowska, M., Niewiadomska, K., & Nicewicz, R. (2022) · Nutrients · doi:10.3390/nu14132710 · Cited by 18 · see citing works
Total sugar intake is associated with higher prevalence of depressive symptoms in obese adults
Li, P., Yin, F., Zhao, Y., Liu, Y., Zhang, R., Wang, J., Lü, W., Wang, Q., & Zhang, J. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2022.1069162 · Cited by 18 · see citing works
Substituting Sugar in Pastry and Bakery Products with Functional Ingredients
Dana, H., & Sonia, A. (2024) · Applied Sciences · doi:10.3390/app14188563 · Cited by 19 · see citing works
Diet quality and anxiety: a critical overview with focus on the gut microbiome
Basso, M., Zorzan, I., Johnstone, N., Barberis, M., & Kadosh, K. C. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1346483 · Cited by 18 · see citing works
Oral health practices and oral hygiene status as indicators of suicidal ideation among adolescents in Southwest Nigeria
Foláyan, M. O., Tantawi, M. E., Oginni, O. A., Oziegbe, E. O., Mapayi, B. M., Arowolo, O., Adeniyi, A. A., & Sam-Agudu, N. A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247073 · Cited by 18 · see citing works
Neurobiological and neuropharmacological aspects of food addiction
Güleken, Z., & Uzbay, T. I. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104760 · Cited by 16 · see citing works
The Synergetic Effect of Soft Drinks and Sweet/Salty Snacks Consumption and the Moderating Role of Obesity on Preadolescents’ Emotions and Behavior: A School-Based Epidemiological Study
Gketsios, I., Tsiampalis, T., Kanellopoulou, A., Vassilakou, T., Notara, V., Αntonogeorgos, G., Gil, A. P. R., Κornilaki, E. N., Lagiou, A., Panagiotakos, D. B., et al. (2023) · Life · doi:10.3390/life13030633 · Cited by 16 · see citing works
Semaglutide restores astrocyte–vascular interactions and blood–brain barrier integrity in a model of diet-induced metabolic syndrome
Estato, V., Obadia, N., Chateaubriand, P. H., Figueiredo, V., Curty, M., Silva, M. C., Ferreira, R. G. L., Santa-Ritta, J., Baroni, M. C., Aragão, A., et al. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-024-01528-0 · Cited by 16 · see citing works
An adiposity force induces obesity in humans independently of a normal energy balance system—a thought experiment
Sørensen, T. I. A. (2023) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2022.0203 · Cited by 15 · see citing works
Ketogenic diet: a potential adjunctive treatment for substance use disorders
Kong, D., Sun, J., Yang, J.-Q., Li, Y.-S., Bi, K., Zhang, Z., Wang, K., Luo, H.-Y., Zhu, M. J., & Xu, Y. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1191903 · Cited by 16 · see citing works
Food addiction as a mediator between depressive symptom severity and body mass index
Bartschi, J. G., & Greenwood, L. (2023) · Appetite · doi:10.1016/j.appet.2023.107008 · Cited by 15 · see citing works
NuMoOS – COVID-19 Nutrition and Mood Online Survey: Perception about dietary aspects, stress, anxiety, and depression in the social isolation of Coronavirus Disease 2019
Negrão, L. D., Natacci, L. C., Alfino, M. C. Z., Marchiori, V. F., Oliveti, D. H., Carioca, A. A. F., & Torres, E. A. F. D. S. (2022) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2022.06.017 · Cited by 16 · see citing works
The Relationship between Diet, Depression, and Alzheimer's Disease: A Narrative Review
Shamsi, H. S. S. A., Rainey‐Smith, S. R., Gardener, S. L., Sohrabi, H. R., Cánovas, R., Martins, R. N., & Fernando, W. M. A. D. B. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202300419 · Cited by 16 · see citing works
Self-Perceived Life Satisfaction during the First Wave of the COVID-19 Pandemic in Sweden: A Cross-Sectional Study
Brogårdh, C. B., Hammarlund, C. S., Eek, F., Stigmar, K., Lindgren, I., Trulsson, A., & Hansson, E. E. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18126234 · Cited by 15 · see citing works
Effect of pH and cosolvent sucralose on the solvation profile of ovalbumin: Ultrasonic and molecular simulation studies
Agalya, P., de Oliveira, I. P., Lescano, C. H., Caires, A. R. L., & Velusamy, V. (2021) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2021.107386 · Cited by 14 · see citing works
Hypnosis reduces food impulsivity in patients with obesity and high levels of disinhibition: HYPNODIET randomized controlled clinical trial
Delestre, F., Lehéricey, G., Estellat, C., Diallo, M. H., Hansel, B., & Giral, P. (2022) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqac046 · Cited by 13 · see citing works
Comparative Analysis of Food Addiction and Obesity: A Critical Review
Maqsood, S., Ahmed, F., Arshad, M. T., Ikram, A., & Abdullahi, M. A. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70799 · Cited by 15 · see citing works
Excess sucrose intake during pregnancy programs fetal brain glucocorticoid receptor expression in female but not male C57Bl/6J mice
Kulhanek, D., Rao, R., & Paulsen, M. E. (2021) · Obesity Science & Practice · doi:10.1002/osp4.506 · Cited by 11 · see citing works
Adverse childhood experiences and unhealthy dietary behaviours in adulthood
Testa, A. M., Zhang, L., Jackson, D. B., Ganson, K. T., Raney, J. H., & Nagata, J. M. (2024) · Public Health Nutrition · doi:10.1017/s1368980024000144 · Cited by 12 · see citing works
The relationship between dietary sugar consumption and anxiety disorders: A systematic review
Wang, X., Wong, A. C. W., Sheng, Z., Wong, S. Y. S., & Yang, X. (2024) · Nutrition Bulletin · doi:10.1111/nbu.12702 · Cited by 12 · see citing works
Growing up strong: The importance of physical, mental, and emotional strength during childhood and adolescence with focus on dietary factors
Leidy, H. J., & Gwin, J. A. (2020) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2020-0058 · Cited by 12 · see citing works
Wideband microstrip antenna for the detection of solutes in water
Mahajan, R. C., & Vyas, V. (2020) · Engineering Reports · doi:10.1002/eng2.12336 · Cited by 11 · see citing works
The Effect of Chronic Alcohol on Cognitive Decline: Do Variations in Methodology Impact Study Outcome? An Overview of Research From the Past 5 Years
Charlton, A. J., & Perry, C. J. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.836827 · Cited by 11 · see citing works
Effects of Prolonged High-Fat Diet Consumption Starting at Different Ages on Behavioral Parameters and Hippocampal Neuroplasticity in Male Mice
Yang, C., Yao, X., Zhang, H., Wang, C., Zhao, J., Xu, D., Xiao, Y., Li, Q., Zhuang, H., Kang, X., et al. (2023) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2201016 · Cited by 10 · see citing works
Dietary intake in children and adolescents with food addiction: A systematic review
Santos, G. C. J., Fernandes, M. S. D. S., Carniel, G. P., Garcêz, A., Leandro, C. G., & Canuto, R. (2024) · Addictive Behaviors Reports · doi:10.1016/j.abrep.2024.100531 · Cited by 13 · see citing works
Anxiety: phenomenology, epidemiology, and risk factors during the novel coronavirus SARS-CoV-2 (COVID-19) pandemic
Merkin, A., Akinfieva, S., Martyushev-Poklad, A. V., Beloskurskaya, O. P., Dinov, E., Ostrovsky, S., Комаров, А. Н., Zakharova, O. Y., Kazhin, V. A., Никифоров, И. А., et al. (2021) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2021-1-107-112 · Cited by 10 · see citing works
TSPO: an emerging role in appetite for a therapeutically promising biomarker
Wang, J., & Beecher, K. (2021) · Open Biology · doi:10.1098/rsob.210173 · Cited by 10 · see citing works
Factors Affecting Psychological Dynamics of Esports Athletes
Nadhirah, N. A., Hidayat, A. A., Suryana, D., Saripah, I., & Suryahadikusumah, A. R. (2023) · Journal of Education and Counseling (JECO) · doi:10.32627/jeco.v3i1.629 · Cited by 9 · see citing works
Neurometabolic effects of sweetened solution intake during adolescence related to depressive-like phenotype in rats
Arcego, D. M., Olivo, L. B., de Moraes, R. O., Garcia, E. D. S., Silveira, A. C. S., Krolow, R., Pereira, N. D. S. C., Lampert, C., Toniazzo, A. P., Nicola, F., et al. (2020) · Nutrition · doi:10.1016/j.nut.2020.110770 · Cited by 9 · see citing works
Marketing placebo effect on consumption of reduced-sugar labeled products
Huang, L., Song, X., & Liu, M. T. (2023) · Asia Pacific Journal of Marketing and Logistics · doi:10.1108/apjml-10-2022-0864 · Cited by 9 · see citing works
Effects of Health-Promoting Lifestyle on Late-Onset Depression in Older Adults: Mediating Effect of Meaning in Life and Interleukin-6 (IL-6)
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Key lifestyles and interim health outcomes for effective interventions in general populations: A network analysis of a large international observational study
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Authors: Jacques, A., Chaaya, N., Beecher, K., Ali, S. A., Belmer, A., & Bartlett, S.
Affiliations: Translational Research Institute (AU)
Corresponding author: Bartlett, Selena
ORCID: Jacques, Angela
Chaaya, Nicholas
Beecher, Kate
Ali, Syed Aoun
Belmer, Arnauld
Bartlett, Selena
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2019-08
Volume: 103
Pages: 178-199
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2019.05.021
OpenAlex: W2945345480
Cited by: 271
References: 398
Citations by year: 2026: 40 · 2025: 44 · 2024: 47 · 2023: 53 · 2022: 42 · 2021: 26 · 2020: 17 · 2019: 2
FWCI: 2.90
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion, cc-by)
PubMed (publishedVersion)
HAL (submittedVersion)
QUT ePrints (Queensland University of Technology) (submittedVersion, cc-by)
Funders: National Health and Medical Research Council
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
Keywords: sugar consumption, sucrose, obesity, stress, emotional processing, addictive behavior, mesocorticolimbic system, dopaminergic system, neuroplasticity, impulse control, anxiety, depression, fear, highly palatable food
MeSH terms: Diet, Carbohydrate Loading, Dietary Sugars, Affective Symptoms, Animals, Mental Disorders, Brain, Feeding Behavior, Humans, Impulsive Behavior, Obesity, Stress, Psychological, Behavior, Addictive, Cognitive Dysfunction

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The impact of sugar consumption on stress driven, emotional and addictive behaviors

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