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STRUCTURE AND PHYSIOLOGIC FUNCTION OF THE LOW-DENSITY LIPOPROTEIN RECEPTOR

Jeon, Hyesung, Blacklow, Stephen C.·2005·Annual Review of Biochemistry
DOI 10.1146/annurev.biochem.74.082803.133354
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Abstract

▪ Abstract The low-density lipoprotein receptor (LDLR) is responsible for uptake of cholesterol-carrying lipoprotein particles into cells. The receptor binds lipoprotein particles at the cell surface and releases them in the low-pH environment of the endosome. The focus of the current review is on biochemical and structural studies of the LDLR and its ligands, emphasizing how structural features of the receptor dictate the binding of low-density lipoprotein (LDL) and beta-migrating forms of very low-density lipoprotein (β-VLDL) particles, how the receptor releases bound ligands at low pH, and how the cytoplasmic tail of the LDLR interfaces with the endocytic machinery.

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Research works printed but not linked: 160

  1. 10.1146/annurev.bi.46.070177.004341 · DOI · Paper page
  2. 10.1146/annurev.cb.01.110185.000245 · DOI · Paper page
  3. 10.1146/annurev.ge.24.120190.001025 · DOI · Paper page
  4. 10.1073/pnas.70.10.2804 · DOI · Paper page
  5. Brown MS, 1974, J. Biol. Chem., 249, 789, 10.1016/S0021-9258(19)42998-0 · DOI
  6. 10.1073/pnas.71.3.788 · DOI
  7. Goldstein JL, 1974, J. Biol. Chem., 249, 5153, 10.1016/S0021-9258(19)42341-7 · DOI · Paper page
  8. 10.1016/0092-8674(84)90388-X · DOI · Paper page
  9. 10.1016/0092-8674(84)90188-0 · DOI · Paper page
  10. 10.1126/science.3873704 · DOI
  11. 10.1126/science.2988123 · DOI · Paper page
  12. 10.1021/bi00601a013 · DOI · Paper page
  13. Weisgraber KH, 1978, J. Biol. Chem., 253, 9053, 10.1016/S0021-9258(17)34284-9 · DOI
  14. 10.1073/pnas.73.7.2434 · DOI · Paper page
  15. 10.1016/0092-8674(77)90022-8 · DOI · Paper page
  16. 10.1038/270695a0 · DOI
  17. 10.1016/0092-8674(78)90276-3 · DOI
  18. 10.1016/0092-8674(83)90052-1 · DOI · Paper page
  19. 10.1002/j.1460-2075.1985.tb03639.x · DOI
  20. 10.1021/bi00386a045 · DOI
  21. 10.1021/bi00386a046 · DOI
  22. 10.1021/bi00386a047 · DOI
  23. DiScipio RG, 1988, J. Biol. Chem., 263, 549, 10.1016/S0021-9258(19)57427-0 · DOI
  24. 10.1073/pnas.86.8.2799 · DOI
  25. 10.1006/jmbi.1998.2115 · DOI
  26. 10.1038/88556 · DOI
  27. Cummings RD, 1983, J. Biol. Chem., 258, 15261, 10.1016/S0021-9258(17)43802-6 · DOI
  28. 10.1016/0092-8674(86)90533-7 · DOI · Paper page
  29. Chen WJ, 1990, J. Biol. Chem., 265, 3116, 10.1016/S0021-9258(19)39742-X · DOI · Paper page
  30. 10.1083/jcb.117.1.39 · DOI · Paper page
  31. 10.1016/S0092-8674(01)00371-3 · DOI · Paper page
  32. 10.1126/science.1078376 · DOI
  33. 10.1016/S0074-7696(01)09011-8 · DOI
  34. 10.1021/bi011894i · DOI
  35. 10.1016/S0092-8674(02)01279-5 · DOI · Paper page
  36. 10.1038/sj.emboj.7600132 · DOI · Paper page
  37. Goldstein JL, Hobbs HH, Brown MS. 2001. InThe Metabolic and Molecular Bases of Inherited Disease, ed.CR Scriver, AL Beaudet, WS Sly, D Valle, pp.2863–913. New York: McGraw-Hill
  38. 10.1016/S0002-9149(98)00215-X · DOI
  39. 10.1002/humu.10102 · DOI
  40. 10.1111/j.1749-6632.1994.tb44298.x · DOI
  41. 10.1016/S1043-2760(01)00526-4 · DOI · Paper page
  42. 10.1016/S0962-8924(02)02282-1 · DOI
  43. 10.1016/S0896-6273(01)00234-3 · DOI
  44. 10.1016/S0959-4388(00)00176-8 · DOI
  45. 10.1034/j.1600-0854.2003.00086_4_5.x · DOI · Paper page
  46. 10.1007/s00018-003-2183-Z · DOI
  47. 10.1242/dev.01117 · DOI · Paper page
  48. 10.1146/annurev.nutr.19.1.141 · DOI
  49. 10.1016/S0166-2236(00)01768-9 · DOI
  50. 10.1194/jlr.R300017-JLR200 · DOI
  51. 10.1097/00041433-200004000-00009 · DOI · Paper page
  52. 10.1016/S0896-6273(01)00234-3 · DOI
  53. 10.1172/JCI200113992 · DOI · Paper page
  54. 10.1172/JCI118149 · DOI
  55. 10.1146/annurev.nutr.21.1.407 · DOI
  56. 10.1016/S0166-2236(00)01722-7 · DOI
  57. Russell DW, 1989, J. Biol. Chem., 264, 21682, 10.1016/S0021-9258(20)88240-4 · DOI · Paper page
  58. Esser V, 1988, J. Biol. Chem., 263, 13282, 10.1016/S0021-9258(18)37702-0 · DOI · Paper page
  59. 10.1021/bi048558x · DOI
  60. Dirlam-Schatz KA, 1998, J. Lipid Res., 39, 402, 10.1016/S0022-2275(20)33901-8 · DOI
  61. 10.1074/jbc.272.41.25531 · DOI · Paper page
  62. 10.1016/S1046-5928(96)90129-1 · DOI
  63. Van Driel IR, 1989, J. Biol. Chem., 264, 9533, 10.1016/S0021-9258(18)60564-2 · DOI
  64. 10.1038/323734a0 · DOI
  65. Chen SH, 1986, J. Biol. Chem., 261, 12918, 10.1016/S0021-9258(18)69248-8 · DOI
  66. 10.1021/bi00282a021 · DOI
  67. Segrest JP, 2001, J. Lipid. Res., 42, 1346, 10.1016/S0022-2275(20)30267-4 · DOI
  68. 10.1016/S0006-3495(95)80392-9 · DOI
  69. 10.1107/S0907444900014608 · DOI
  70. 10.1073/pnas.96.15.8420 · DOI
  71. Segrest JP, 1999, J. Lipid Res., 40, 1401, 10.1016/S0022-2275(20)33382-4 · DOI
  72. Chatterton JE, 1995, J. Lipid Res., 36, 2027, 10.1016/S0022-2275(20)41120-4 · DOI
  73. Milne R, 1989, J. Biol. Chem., 264, 19754, 10.1016/S0021-9258(19)47176-7 · DOI
  74. Welty FK, 1995, J. Lipid Res., 36, 2622, 10.1016/S0022-2275(20)41098-3 · DOI
  75. Krul ES, 1992, J. Lipid Res., 33, 1037, 10.1016/S0022-2275(20)41419-1 · DOI
  76. 10.1038/323738a0 · DOI
  77. 10.1073/pnas.84.19.6919 · DOI
  78. 10.1126/science.2994225 · DOI
  79. 10.1172/JCI1847 · DOI
  80. 10.1074/jbc.M008890200 · DOI
  81. Wetterau JR, 1988, J. Biol. Chem., 263, 6240, 10.1016/S0021-9258(18)68778-2 · DOI · Paper page
  82. McLean JW, 1984, J. Biol. Chem., 259, 6498, 10.1016/S0021-9258(20)82169-3 · DOI
  83. 10.1126/science.3283935 · DOI · Paper page
  84. Innerarity TL, 1979, J. Biol. Chem., 254, 4186, 10.1016/S0021-9258(18)50713-4 · DOI · Paper page
  85. Weisgraber KH, 1982, J. Biol. Chem., 257, 2518, 10.1016/S0021-9258(18)34954-8 · DOI · Paper page
  86. 10.1073/pnas.90.5.1977 · DOI · Paper page
  87. Weisgraber KH, 1983, J. Biol. Chem., 258, 12348, 10.1016/S0021-9258(17)44181-0 · DOI · Paper page
  88. Lalazar A, 1988, J. Biol. Chem., 263, 3542, 10.1016/S0021-9258(18)68957-4 · DOI · Paper page
  89. Zaiou M, 2000, J. Lipid Res., 41, 1087, 10.1016/S0022-2275(20)32014-9 · DOI
  90. 10.1074/jbc.275.4.2576 · DOI
  91. 10.1073/pnas.76.5.2311 · DOI · Paper page
  92. Weisgraber KH, Lund-Katz S, Phillips MC. 1992. InHigh Density Lipoproteins and Atherosclerosis III, ed.NE Miller, AR Tall, pp.175–81. Amsterdam: Elsevier
  93. 10.1074/jbc.273.40.25825 · DOI
  94. Fisher CA, 1999, J. Lipid Res., 40, 93, 10.1016/S0022-2275(20)33343-5 · DOI
  95. 10.1074/jbc.M002643200 · DOI
  96. 10.1074/jbc.M005265200 · DOI
  97. 10.1074/jbc.M003508200 · DOI · Paper page
  98. 10.1074/jbc.M301753200 · DOI
  99. Pitas RE, 1980, J. Biol. Chem., 255, 5454, 10.1016/S0021-9258(19)70808-4 · DOI · Paper page
  100. Dyer CA, 1991, J. Biol. Chem., 266, 22803, 10.1016/S0021-9258(18)54425-2 · DOI
  101. Dyer CA, 1995, J. Lipid Res., 36, 80, 10.1016/S0022-2275(20)39756-X · DOI
  102. 10.1172/JCI1099 · DOI
  103. 10.1021/bi036208p · DOI
  104. 10.1101/gr.849004 · DOI
  105. 10.1021/bi00040a017 · DOI
  106. 10.1016/0014-5793(95)00939-7 · DOI
  107. 10.1038/nsb0996-758 · DOI
  108. 10.1073/pnas.92.14.6334 · DOI
  109. 10.1021/bi00044a025 · DOI
  110. 10.1073/pnas.76.11.5577 · DOI
  111. Beisiegel U, 1981, J. Biol. Chem., 256, 11923, 10.1016/S0021-9258(19)68494-2 · DOI · Paper page
  112. van Driel IR, 1987, J. Biol. Chem., 262, 17443, 10.1016/S0021-9258(18)45399-9 · DOI
  113. 10.1111/j.1432-1033.1996.0214u.x · DOI
  114. 10.1021/bi972529n · DOI
  115. 10.1110/ps.9.7.1282 · DOI
  116. 10.1021/bi992087a · DOI
  117. 10.1021/bi982022s · DOI
  118. 10.1128/JVI.75.5.2051-2058.2001 · DOI
  119. 10.1016/S0014-5793(01)03086-1 · DOI
  120. 10.1021/bi015688m · DOI
  121. 10.1021/bi9821622 · DOI · Paper page
  122. 10.1038/41798 · DOI
  123. 10.1128/JVI.76.6.2848-2856.2002 · DOI
  124. 10.1074/jbc.275.5.3264 · DOI
  125. 10.1074/jbc.274.20.14130 · DOI
  126. 10.1016/S0014-5793(00)01842-1 · DOI
  127. 10.1021/bi0027276 · DOI
  128. 10.1126/science.1078124 · DOI · Paper page
  129. 10.1038/nsmb753 · DOI
  130. 10.1002/humu.1380010602 · DOI · Paper page
  131. 10.1074/jbc.M401412200 · DOI
  132. Mikhailenko I, 1999, J. Cell Sci., 112, 3269, 10.1242/jcs.112.19.3269 · DOI · Paper page
  133. 10.1093/nar/26.1.248 · DOI
  134. 10.1042/bj2770677 · DOI
  135. 10.1021/bi002322l · DOI
  136. 10.1016/S0969-2126(01)00606-2 · DOI
  137. 10.1006/jmbi.2001.4867 · DOI
  138. 10.1016/S0092-8674(00)81259-3 · DOI
  139. 10.1107/S0907444903021383 · DOI
  140. 10.1074/jbc.M002582200 · DOI
  141. 10.1074/jbc.M002583200 · DOI
  142. 10.1016/j.molcel.2004.09.038 · DOI
  143. 10.1016/j.sbi.2003.10.001 · DOI
  144. 10.1038/nature01873 · DOI
  145. 10.1016/0092-8674(76)90130-6 · DOI
  146. Davis CG, 1987, J. Biol. Chem., 262, 4075, 10.1016/S0021-9258(18)61313-4 · DOI · Paper page
  147. 10.1016/0092-8674(91)90295-A · DOI · Paper page
  148. 10.1126/science.1060458 · DOI · Paper page
  149. 10.1172/JCI200216445 · DOI
  150. 10.1126/science.7527937 · DOI
  151. Blaikie P, 1994, J. Biol. Chem., 269, 32031, 10.1016/S0021-9258(18)31593-X · DOI
  152. 10.1128/MCB.19.7.5179 · DOI · Paper page
  153. 10.1034/j.1600-0854.2001.020206.x · DOI · Paper page
  154. 10.1073/pnas.252630799 · DOI · Paper page
  155. 10.1074/jbc.M308870200 · DOI
  156. 10.1016/S0969-2126(03)00068-6 · DOI · Paper page
  157. 10.1074/jbc.M304384200 · DOI
  158. 10.1021/bi049092l · DOI
  159. Fisher C, 2001, Nature Encyclopedia of Life Sciences
  160. 10.1016/S0969-2126(03)00010-8 · DOI

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Metadata

Authors
Jeon, H., & Blacklow, S. C.
Venue
Annual Review of Biochemistry
Publisher
Annual Reviews
Published
2005-06-01
Volume
74
Issue
1
Pages
535-562
ISSN
  • 0066-4154
  • 1545-4509
DOI
10.1146/annurev.biochem.74.082803.133354
Cited by
310
References
10
Language
en

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