Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men

Cites (782)

Items 201–400 of 781

1. Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs
   Lovis, Pascal, Gattesco, Sonia, Regazzi, Romano · 2008 · bchm
2. SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells
   Eliasson, Lena, Ma, Xiaosong, Renström, Erik, Barg, Sebastian, Berggren, Per-Olof, Galvanovskis, Juris, Gromada, Jesper, Jing, Xingjun, Lundquist, Ingmar, Salehi, Albert et al. · 2003 · The Journal of General Physiology
3. Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells
   Barg, Sebastian, Ma, Xiaosong, Eliasson, Lena, Galvanovskis, Juris, Göpel, Sven O., Obermüller, Stefanie, Platzer, Josef, Renström, Erik, Trus, Michel, Atlas, Daphne et al. · 2001 · Biophysical Journal
4. Age- and sex-related prevalence of diabetes mellitus among immigrants to Ontario, Canada
   Maria Isabella Creatore, Rahim Moineddin, Gillian L. Booth, Douglas G. Manuel, Marie DesMeules, Sarah McDermott, Richard Henry Glazier · 2010 · Canadian Medical Association Journal
5. Type 2 diabetes: new genes, new understanding
   Prokopenko, Inga, McCarthy, Mark I., Lindgren, Cecilia M. · 2008 · Trends in Genetics
6. Structure of a Pancreatic ATP-Sensitive Potassium Channel
   Li, Ningning, Wu, Jing-Xiang, Ding, Dian, Cheng, Jiaxuan, Gao, Ning, Chen, Lei · 2017 · Cell
7. Perspectives on Kiss-and-Run: Role in Exocytosis, Endocytosis, and Neurotransmission
   AbdulRasheed A. Alabi, Richard W. Tsien · 2011 · Annual Review of Physiology
8. A KATP Channel-Dependent Pathway within α Cells Regulates Glucagon Release from Both Rodent and Human Islets of Langerhans
   Patrick E. MacDonald, Yang Z. De Marinis, Reshma D. Ramracheya, Albert A. Salehi, Xiaosong Ma, Paul Johnson, Roger Cox, Lena Eliasson, Patrik Rorsman · 2007 · PLoS Biology
9. The ATP‐sensitivity of K⁺ channels in rat pancreatic B‐cells is modulated by ADP
   Kakei, Masafumi, Kelly, Ronan P., Ashcroft, Stephen J.H., Ashcroft, Frances M. · 1986 · FEBS Letters
10. The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation
    Miriam Cnop, Stephen J. Hughes, Mariana Igoillo‐Esteve, Michael B. Hoppa, Farhina Sayyed, Lianne van de Laar, Jennifer H. Gunter, Eelco J.P. de Koning, Gerard V. Walls, D. W. G. Gray et al. · 2009 · Diabetologia
11. The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance
    Motoyuki Tamaki, Yoshio Fujitani, Akemi Hara, Toyoyoshi Uchida, Yoshifumi Tamura, Kageumi Takeno, Minako Kawaguchi, Takahiro Watanabe, Takeshi Ogihara, Ayako Fukunaka et al. · 2013 · Journal of Clinical Investigation
12. γ-Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic β-Cells
    Braun, Matthias, Ramracheya, Reshma, Bengtsson, Martin, Clark, Anne, Walker, Jonathan N., Johnson, Paul R., Rorsman, Patrik · 2010 · Diabetes
13. Perspective on the Genetics and Diagnosis of Congenital Hyperinsulinism Disorders
    Stanley, Charles A. · 2016 · The Journal of Clinical Endocrinology & Metabolism
14. Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes
    Rosengren, Anders H., Braun, Matthias, Mahdi, Taman, Andersson, Sofia A., Travers, Mary E., Shigeto, Makoto, Zhang, Enming, Almgren, Peter, Ladenvall, Claes, Axelsson, Annika S. et al. · 2012 · Diabetes
15. Zinc and insulin in pancreatic beta-cells
    Yang V. Li · 2014 · Endocrine
16. Leucine metabolism in regulation of insulin secretion from pancreatic beta cells: Nutrition Reviews©, Vol. 68, No. 5
    Yang, Jichun, Chi, Yujing, Burkhardt, Brant R, Guan, Youfei, Wolf, Bryan A · 2010 · Nutrition Reviews
17. Impaired insulin secretion and glucose tolerance in β cell‐selective CaV1.2 Ca2+ channel null mice
    Schulla, Verena, Renström, Erik, Feil, Robert, Feil, Susanne, Franklin, Isobel, Gjinovci, Asllan, Jing, Xing‐Jun, Laux, Dirk, Lundquist, Ingmar, Magnuson, Mark A. et al. · 2003 · The EMBO Journal
18. Glucose metabolism in mouse pancreatic islets
    S. J. H. Ashcroft, C. J. Hedeskov, P J Randle · 1970 · Biochemical Journal
19. Impaired Gene and Protein Expression of Exocytotic Soluble <i>N</i> -Ethylmaleimide Attachment Protein Receptor Complex Proteins in Pancreatic Islets of Type 2 Diabetic Patients
    Ostenson, Claes-Goran, Gaisano, Herbert, Sheu, Laura, Tibell, Annika, Bartfai, Tamas · 2006 · Diabetes
20. Pancreatic β-Cell-specific Targeted Disruption of Glucokinase Gene
    Yasuo Terauchi, Hiroshi Sakura, Kazuki Yasuda, Keiji Iwamoto, Noriko K. Takahashi, Kouichi Ito, Haruo Kasai, Hiroshi I. Suzuki, Otoya Ueda, Nobuo Kamada et al. · 1995 · Journal of Biological Chemistry
21. Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic β-cells
    G. Trube, P. Rorsman, T. Ohno-Shosaku · 1986 · Pflügers Archiv
22. Intracellular ADP activates K⁺ channels that are inhibited by ATP in an insulin‐secreting cell line
    Dunne, Mark J., Petersen, Ole H. · 1986 · FEBS Letters
23. Nutrient Control of Insulin Secretion in Isolated Normal Human Islets
    Henquin, Jean-Claude, Dufrane, Denis, Nenquin, Myriam · 2006 · Diabetes
24. The Rab27a/Granuphilin Complex Regulates the Exocytosis of Insulin-Containing Dense-Core Granules
    Yi, Zhaohong, Yokota, Hiromi, Torii, Seiji, Aoki, Takeo, Hosaka, Masahiro, Zhao, Shengli, Takata, Kuniaki, Takeuchi, Toshiyuki, Izumi, Tetsuro · 2002 · Molecular and Cellular Biology
25. A Subset of 50 Secretory Granules in Close Contact With <scp>l</scp>-Type Ca2+ Channels Accounts for First-Phase Insulin Secretion in Mouse β-Cells
    Barg, Sebastian, Eliasson, Lena, Renström, Erik, Rorsman, Patrik · 2002 · Diabetes
26. Voltage‐gated and resting membrane currents recorded from B‐cells in intact mouse pancreatic islets
    Göpel, S., Kanno, T., Barg, S., Galvanovskis, J., Rorsman, P. · 1999 · The Journal of Physiology
27. Rapid ATP‐Dependent Priming of Secretory Granules Precedes Ca ²⁺ ‐Induced Exocytosis in Mouse Pancreatic B‐Cells
    Eliasson, Lena, Renström, Erik, Ding, Wei‐Guang, Proks, Peter, Rorsman, Patrik · 1997 · The Journal of Physiology
28. Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets
    Adriaenssens, Alice E., Svendsen, Berit, Lam, Brian Y. H., Yeo, Giles S. H., Holst, Jens J., Reimann, Frank, Gribble, Fiona M. · 2016 · Diabetologia
29. Sulfonylurea Receptor Type 1 Knock-out Mice Have Intact Feeding-stimulated Insulin Secretion despite Marked Impairment in Their Response to Glucose
    Chiyo Shiota, Olof Larsson, Kathy D. Shelton, Masakazu Shiota, Alexander M. Efanov, Marianne Høy, Jill Lindner, Suwattanee Kooptiwut, Lisa Juntti‐Berggren, Jesper Gromada et al. · 2002 · Journal of Biological Chemistry
30. ATP-Sensitive K+ Channels in Pancreatic β-Cells: Spare-Channel Hypothesis
    D. Cook, L. Satin, M. Ashford, C. Hales · 1988 · Diabetes
31. Insulin Signaling in the Pancreatic β-Cell
    Ingo B. Leibiger, Barbara Leibiger, Per‐Olof Berggren · 2008 · Annual Review of Nutrition
32. Regulation of calcium in pancreatic α- and β-cells in health and disease
    Rorsman, Patrik, Braun, Matthias, Zhang, Quan · 2012 · Cell Calcium
33. The cAMP Sensor Epac2 Is a Direct Target of Antidiabetic Sulfonylurea Drugs
    Chang-Liang Zhang, M Katoh, Tadao Shibasaki · 2009 · Science
34. Glutamate Is a Positive Autocrine Signal for Glucagon Release
    Cabrera, Over, Jacques-Silva, M. Caroline, Speier, Stephan, Yang, Shao-Nian, Köhler, Martin, Fachado, Alberto, Vieira, Elaine, Zierath, Juleen R., Kibbey, Richard, Berman, Dora M. et al. · 2008 · Cell Metabolism
35. Functional Expression of the Murine Connexin 36 Gene Coding for a Neuron-Specific Gap Junctional Protein
    Teubner, B., Degen, J., Söhl, G., Güldenagel, M., Bukauskas, F.F., Trexler, E.B., Verselis, V.K., De Zeeuw, C.I., Lee, C.G., Kozak, C.A. et al. · 2000 · The Journal of Membrane Biology
36. Potassium permeability activated by intracellular calcium ion concentration in the pancreatic beta‐cell.
    Illani J. Atwater, C M Dawson, Bernard Ribalet, E Rojas · 1979 · The Journal of Physiology
37. Isoform-specific regulation of mood behavior and pancreatic β cell and cardiovascular function by L-type Ca2+ channels
    Martina J. Sinnegger-Brauns, Alfred Hetzenauer, Irene G. Huber, Erik Renström, Georg Wietzorrek, Stanislav Berjukow, Maurizio Cavalli, Doris Walter, Alexandra Koschak, Ralph Waldschütz et al. · 2004 · Journal of Clinical Investigation
38. Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis
    Ohara-Imaizumi, Mica, Fujiwara, Tomonori, Nakamichi, Yoko, Okamura, Tadashi, Akimoto, Yoshihiro, Kawai, Junko, Matsushima, Satsuki, Kawakami, Hayato, Watanabe, Takashi, Akagawa, Kimio et al. · 2007 · The Journal of Cell Biology
39. Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to <i>HHEX</i> , <i>SOX4</i> , and <i>IRX3</i>
    Ragvin, Anja, Moro, Enrico, Fredman, David, Navratilova, Pavla, Drivenes, Øyvind, Engström, Pär G., Alonso, M. Eva, Mustienes, Elisa de la Calle, Skarmeta, José Luis Gómez, Tavares, Maria J. et al. · 2010 · Proceedings of the National Academy of Sciences
40. Delay between Fusion Pore Opening and Peptide Release from Large Dense-Core Vesicles in Neuroendocrine Cells
    Barg, Sebastian, Olofsson, Charlotta S., Schriever-Abeln, Jenny, Wendt, Anna, Gebre-Medhin, Samuel, Renström, Erik, Rorsman, Patrik · 2002 · Neuron
41. Lipotoxicity disrupts incretin-regulated human β cell connectivity
    Hodson, David J., Mitchell, Ryan K., Bellomo, Elisa A., Sun, Gao, Vinet, Laurent, Meda, Paolo, Li, Daliang, Li, Wen-Hong, Bugliani, Marco, Marchetti, Piero et al. · 2013 · Journal of Clinical Investigation
42. Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells
    Z�nkler, B.J., Lenzen, S., Manner, K., Panten, U., Trube, G. · 1988 · Naunyn-Schmiedeberg's Archives of Pharmacology
43. CaV2.3 calcium channels control second-phase insulin release
    Xingjun Jing, Daiqing Li, Charlotta S. Olofsson, Albert A. Salehi, Vikas V. Surve, José Caballero, Rosita Ivarsson, Ingmar Lundquist, Alexey Pereverzev, Toni Schneider et al. · 2005 · Journal of Clinical Investigation
44. GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus
    McCulloch, Laura J., van de Bunt, Martijn, Braun, Matthias, Frayn, Keith N., Clark, Anne, Gloyn, Anna L. · 2011 · Molecular Genetics and Metabolism
45. Aging-Dependent Demethylation of Regulatory Elements Correlates with Chromatin State and Improved β Cell Function
    Avrahami, Dana, Li, Changhong, Zhang, Jia, Schug, Jonathan, Avrahami, Ran, Rao, Shilpa, Stadler, Michael B., Burger, Lukas, Schübeler, Dirk, Glaser, Benjamin et al. · 2015 · Cell Metabolism
46. Glucose‐induced oscillations of intracellular Ca²⁺ concentration resembling bursting electrical activity in single mouse islets of Langerhans
    Valdeolmillos, Miguel, Santos, Rosa M., Contreras, Diego, Soria, Bernat, Rosario, Luis M. · 1989 · FEBS Letters
47. Rapid insulinotropic effect of 17β‐estradiol via a plasma membrane receptor
    Ángel Nadal, Juan Manuel Rovira, Ouahiba Laribi, Trinidad León‐Quinto, Etelvina Andreu, Cristina Ripoll, Bernat Soria · 1998 · The FASEB Journal
48. Tomographic molecular imaging and 3D quantification within adult mouse organs
    Tomas Alanentalo, Amir Asayesh, Harris Morrison · 2006 · Nature Methods
49. Reconstitution of Muscarinic Modulation of the KCNQ2/KCNQ3 K⁺Channels That Underlie the Neuronal M Current
    Shapiro, Mark S., Roche, John P., Kaftan, Edward J., Cruzblanca, Humberto, Mackie, Ken, Hille, Bertil · 2000 · The Journal of Neuroscience
50. The insulin secretory granule as a signaling hub
    Suckale, Jakob, Solimena, Michele · 2010 · Trends in Endocrinology &amp; Metabolism
51. Loss of high-frequency glucose-induced Ca 2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5 −/− mice
    Barbara Colsoul, Anica Schraenen, Katleen Lemaire, Roel Quintens, Leentje Van Lommel, Andrei Segal, Grzegorz Owsianik, Karel Talavera, Thomas Voets, Robert F. Margolskee et al. · 2010 · Proceedings of the National Academy of Sciences
52. Novel aspects of the molecular mechanisms controlling insulin secretion
    Eliasson, Lena, Abdulkader, Fernando, Braun, Matthias, Galvanovskis, Juris, Hoppa, Michael B., Rorsman, Patrik · 2008 · The Journal of Physiology
53. Piccolo, a Ca2+ Sensor in Pancreatic β-Cells
    Kei Fujimoto, Tadao Shibasaki, Norihide Yokoi, Yasushige Kashima, Masanari Matsumoto, Takashi Sasaki, Naoko Tajima, Toshihiko Iwanaga, Susumu Seino · 2002 · Journal of Biological Chemistry
54. Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.
    Rebecca Ashfield, Fiona Mary Gribble, S. J. H. Ashcroft, Frances M. Ashcroft · 1999 · Diabetes
55. Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating
    Martin, Gregory M, Yoshioka, Craig, Rex, Emily A, Fay, Jonathan F, Xie, Qing, Whorton, Matthew R, Chen, James Z, Shyng, Show-Ling · 2017 · eLife
56. Signals and pools underlying biphasic insulin secretion.
    Henquin, Jean-Claude, Ishiyama, Nobuyoshi, Nenquin, Myriam, Ravier, Magalie A., Jonas, Jean-Christophe · 2002 · Diabetes
57. Sodium Channels, Inherited Epilepsy, and Antiepileptic Drugs
    William A. Catterall · 2014 · The Annual Review of Pharmacology and Toxicology
58. Secreted Frizzled-Related Protein 4 Reduces Insulin Secretion and Is Overexpressed in Type 2 Diabetes
    Taman Mahdi, Sonja Hänzelmann, Albert A. Salehi, Sarheed J. Muhammed, Thomas M. Reinbothe, Yunzhao Tang, Annika S. Axelsson, Yuedan Zhou, Xingjun Jing, Peter Almgren et al. · 2012 · Cell Metabolism
59. Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification
    Barg, Sebastian, Huang, Ping, Eliasson, Lena, Nelson, Deborah J., Obermüller, Stefanie, Rorsman, Patrik, Thévenod, Frank, Renström, Erik · 2001 · Journal of Cell Science
60. Glucose-Induced Cyclic AMP Oscillations Regulate Pulsatile Insulin Secretion
    Dyachok, Oleg, Idevall-Hagren, Olof, Sågetorp, Jenny, Tian, Geng, Wuttke, Anne, Arrieumerlou, Cécile, Akusjärvi, Göran, Gylfe, Erik, Tengholm, Anders · 2008 · Cell Metabolism
61. Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient <i>ob/ob</i> mice
    Seufert, Jochen, Kieffer, Timothy J., Habener, Joel F. · 1999 · Proceedings of the National Academy of Sciences
62. PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic β Cells
    Lena Eliasson, Erik Renström, Carina Ämmälä, Per‐Olof Berggren, Alejandro M. Bertorello, Krister B. Bokvist, Alexander Chibalin, Jude T. Deeney, Peter R. Flatt, Jakob Gäbel et al. · 1996 · Science
63. Electrophysiology of Stimulus-Secretion Coupling in Human β-Cells
    Misler, Stanley, Barnett, David W, Gillis, Kevin D, Pressel, David M · 1992 · Diabetes
64. Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome
    Nica, Alexandra C., Ongen, Halit, Irminger, Jean-Claude, Bosco, Domenico, Berney, Thierry, Antonarakis, Stylianos E., Halban, Philippe A., Dermitzakis, Emmanouil T. · 2013 · Genome Research
65. Glucagon-Like Peptide 1(7-36) Amide Stimulates Exocytosis in Human Pancreatic β-Cells by Both Proximal and Distal Regulatory Steps in Stimulus-Secretion Coupling
    Jesper Gromada, Krister B. Bokvist, Wei‐Guang Ding, Jens Juul Holst, Jens Høiriis Nielsen, Patrik Rorsman · 1998 · Diabetes
66. GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
    Shigeto, Makoto, Ramracheya, Reshma, Tarasov, Andrei I., Cha, Chae Young, Chibalina, Margarita V., Hastoy, Benoit, Philippaert, Koenraad, Reinbothe, Thomas, Rorsman, Nils, Salehi, Albert et al. · 2015 · Journal of Clinical Investigation
67. Differences in Glucose Transporter Gene Expression between Rat Pancreatic α- and β-Cells Are Correlated to Differences in Glucose Transport but Not in Glucose Utilization
    Heimberg, Harry, De Vos, Anick, Pipeleers, Daniel, Thorens, Bernard, Schuit, Frans · 1995 · Journal of Biological Chemistry
68. Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
    Carina Ämmälä, Lena Eliasson, Krister B. Bokvist, Per‐Olof Berggren, Richard E. Honkanen, Åke Sjöholm, Patrik Rorsman · 1994 · Proceedings of the National Academy of Sciences
69. Increased Activity of L-Type Ca 2+ Channels Exposed to Serum from Patients with Type I Diabetes
    Lisa Juntti‐Berggren, Olof Larsson, Patrik Rorsman, Carina Ämmälä, Krister B. Bokvist, Karin Wåhlander, Pierluigi Nicotera, Jeanette Dypbukt, Sten Orrenius, Anders Hallberg et al. · 1993 · Science
70. Neurotransmitter-Induced Inhibition of Exocytosis in Insulin-Secreting β Cells by Activation of Calcineurin
    Renström, Erik, Ding, Wei-Guang, Bokvist, Krister, Rorsman, Patrik · 1996 · Neuron
71. Dual Functional Role of Membrane Depolarization/Ca2+ Influx in Rat Pancreatic B-Cell
    Sato, Yoshihiko, Aizawa, Toru, Komatsu, Mitsuhisa, Okada, Naomi, Yamada, Takashi · 1992 · Diabetes
72. Cyclic changes in potential and resistance of the beta‐cell membrane induced by glucose in islets of Langerhans from mouse.
    Illani J. Atwater, Bernard Ribalet, E Rojas · 1978 · The Journal of Physiology
73. Functional analysis of a structural model of the ATP‐binding site of the KATP channel Kir6.2 subunit
    Jennifer F. Antcliff, Shozeb M Haider, Peter Proks, Mark S.P. Sansom, Frances Mary Ashcroft · 2005 · The EMBO Journal
74. Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice
    Otani, Kenichi, Kulkarni, Rohit N., Baldwin, Aaron C., Krutzfeldt, Jan, Ueki, Kohjiro, Stoffel, Markus, Kahn, C. Ronald, Polonsky, Kenneth S. · 2004 · American Journal of Physiology-Endocrinology and Metabolism
75. Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation
    Lieven Thorrez, Ilaria Laudadio, Katrijn Van Deun, Roel Quintens, Nico Hendrickx, Mikaela Granvik, Katleen Lemaire, Anica Schraenen, Leentje Van Lommel, Stefan Lehnert et al. · 2010 · Genome Research
76. Opposite effects of tolbutamide and diazoxide on 86Rb+ fluxes and membrane potential in pancreatic B cells
    Jean‐Claude Henquin, Hans Peter Meissner · 1982 · Biochemical Pharmacology
77. Kv2.1 Ablation Alters Glucose-Induced Islet Electrical Activity, Enhancing Insulin Secretion
    Jacobson, David A., Kuznetsov, Andrey, Lopez, James P., Kash, Shera, Ämmälä, Carina E., Philipson, Louis H. · 2007 · Cell Metabolism
78. Modeling Phasic Insulin Release
    Nesher, Rafael, Cerasi, Erol · 2002 · Diabetes
79. Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation
    Kazuo Kasai, Mica Ohara‐Imaizumi, Noriko K. Takahashi, Shin Mizutani, Shengli Zhao, Toshiteru Kikuta, Haruo Kasai, Shinya Nagamatsu, Hiroshi Gomi, Tetsuro Izumi · 2005 · Journal of Clinical Investigation
80. Na channels and two types of Ca channels in rat pancreatic B cells identified with the reverse hemolytic plaque assay.
    Hiriart, M, Matteson, D R · 1988 · The Journal of general physiology
81. Properties and calcium‐dependent inactivation of calcium currents in cultured mouse pancreatic B‐cells.
    Plant, T D · 1988 · The Journal of Physiology
82. Hierarchy of the β‐cell signals controlling insulin secretion
    J. C. Henquin, Magalie A. Ravier, Myriam Nenquin, Jean‐Christophe Jonas, Patrick Gilon · 2003 · European Journal of Clinical Investigation
83. The importance of free fatty acids in the development of Type 2 diabetes
    John P.H. Wilding · 2007 · Diabetic Medicine
84. Differential Expression of GAD65 and GAD67 in Human, Rat, and Mouse Pancreatic Islets
    Kim, John, Richter, Wiltrud, Aanstoot, Henk-Jan, Shi, Yuguang, Fu, Qin, Rajotte, Ray, Warnock, Garth, Baekkeskov, Steinunn · 1993 · Diabetes
85. Interaction of ATP Sensor, cAMP Sensor, Ca2+ Sensor, and Voltage-dependent Ca2+ Channel in Insulin Granule Exocytosis
    Tadao Shibasaki, Yasuhiro Sunaga, Kei Fujimoto, Yasushige Kashima, Susumu Seino · 2004 · Journal of Biological Chemistry
86. The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells
    Tarasov, Andrei I., Semplici, Francesca, Ravier, Magalie A., Bellomo, Elisa A., Pullen, Timothy J., Gilon, Patrick, Sekler, Israel, Rizzuto, Rosario, Rutter, Guy A. · 2012 · PLoS ONE
87. Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
    Jonathan N. Walker, Reshma D. Ramracheya, Quan Zhang, Paul Johnson, M. Braun, Patrik Rorsman · 2011 · Diabetes Obesity and Metabolism
88. Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
    Natalia Petersen, Ye Lao, Anton Maximov, Jen-Chieh Chuang, Elena Yu. Kostromina, Joyce J. Repa, Cai Li, George Karoly Radda, Thomas Christian Südhof, Weiping Han · 2008 · Proceedings of the National Academy of Sciences
89. Electrophysiological evidence for coupling between β cells of pancreatic islets
    H. P. Meissner · 1976 · Nature
90. Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.
    Per O. G. Arkhammar, Thomas Nilsson, Patrik Rorsman, Per‐Olof Berggren · 1987 · Journal of Biological Chemistry
91. MgATP activates the β cell K _ATP channel by interaction with its SUR1 subunit
    Gribble, Fiona M., Tucker, Stephen J., Haug, Trude, Ashcroft, Frances M. · 1998 · Proceedings of the National Academy of Sciences
92. Interplay between cytoplasmic Ca2+ and the ATP/ADP ratio: a feedback control mechanism in mouse pancreatic islets
    DETIMARY, Philippe, GILON, Patrick, HENQUIN, Jean-Claude · 1998 · Biochemical Journal
93. Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP
    Trapp, Stefan, Proks, Peter, Tucker, Stephen J., Ashcroft, Frances M. · 1998 · The Journal of General Physiology
94. Simultaneous recordings of glucose dependent electrical activity and ATP‐regulated K⁺‐currents in isolated mouse pancreatic β‐cells
    Smith, Paul A., Ashcroft, Frances M., Rorsman, Patrik · 1990 · FEBS Letters
95. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells
    Ferdaoussi, Mourad, Dai, Xiaoqing, Jensen, Mette V., Wang, Runsheng, Peterson, Brett S., Huang, Chao, Ilkayeva, Olga, Smith, Nancy, Miller, Nathanael, Hajmrle, Catherine et al. · 2015 · Journal of Clinical Investigation
96. 3‐D structural and functional characterization of the purified KATP channel complex Kir6.2–SUR1
    Mikhailov, Michael V, Campbell, Jeff D, de Wet, Heidi, Shimomura, Kenju, Zadek, Brittany, Collins, Richard F, Sansom, Mark SP, Ford, Robert C, Ashcroft, Frances M · 2005 · The EMBO Journal
97. Glucagon is the key factor in the development of diabetes
    Young H. Lee, May-Yun Wang, Xinxin Yu, Roger H. Unger · 2016 · Diabetologia
98. In Vivo and In Vitro Glucose-Induced Biphasic Insulin Secretion in the Mouse
    Henquin, Jean-Claude, Nenquin, Myriam, Stiernet, Patrick, Ahren, Bo · 2006 · Diabetes
99. Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics
    Speier, Stephan, Gjinovci, Asllan, Charollais, Anne, Meda, Paolo, Rupnik, Marjan · 2007 · Diabetes
100. Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells
     Pérez-Armendariz, M., Roy, C., Spray, D.C., Bennett, M.V. · 1991 · Biophysical Journal
101. Granuphilin molecularly docks insulin granules to the fusion machinery
     Hiroshi Gomi, Shin Mizutani, Kazuo Kasai, Shigeyoshi Itohara, Tetsuro Izumi · 2005 · The Journal of Cell Biology
102. SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells
     Kailey, Balrik, van de Bunt, Martijn, Cheley, Stephen, Johnson, Paul R., MacDonald, Patrick E., Gloyn, Anna L., Rorsman, Patrik, Braun, Matthias · 2012 · American Journal of Physiology-Endocrinology and Metabolism
103. Rare and Common Genetic Events in Type 2 Diabetes: What Should Biologists Know?
     Amélie Bonnefond, Philippe Froguel · 2015 · Cell Metabolism
104. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment
     Marquard, Jan, Otter, Silke, Welters, Alena, Stirban, Alin, Fischer, Annelie, Eglinger, Jan, Herebian, Diran, Kletke, Olaf, Klemen, Maša Skelin, Stožer, Andraž et al. · 2015 · Nature Medicine
105. The Interaction of nucleotides with the tolbutamide block of cloned atp‐sensitive k⁺ channel currents expressed in xenopus oocytes: a reinterpretation
     Gribble, Fiona M., Tucker, Stephen J., Ashcroft, Frances M. · 1997 · The Journal of Physiology
106. Capacitance measurements of exocytosis in mouse pancreatic α‐, β‐ and δ‐cells within intact islets of Langerhans
     Göpel, Sven, Zhang, Quan, Eliasson, Lena, Ma, Xiao‐Song, Galvanovskis, Juris, Kanno, Takahiro, Salehi, Albert, Rorsman, Patrik · 2004 · The Journal of Physiology
107. Glucose-stimulated Cdc42 Signaling Is Essential for the Second Phase of Insulin Secretion
     Wang, Zhanxiang, Oh, Eunjin, Thurmond, Debbie C. · 2007 · Journal of Biological Chemistry
108. The Changes in Adenine Nucleotides Measured in Glucose-stimulated Rodent Islets Occur in β Cells but Not in α Cells and Are Also Observed in Human Islets
     Detimary, Philippe, Dejonghe, Sandra, Ling, Zhidong, Pipeleers, Daniel, Schuit, Frans, Henquin, Jean-Claude · 1998 · Journal of Biological Chemistry
109. Involvement of the Rab27 Binding Protein Slac2c/MyRIP in Insulin Exocytosis
     Waselle, Laurent, Coppola, Thierry, Fukuda, Mitsunori, Iezzi, Mariella, El-Amraoui, Aziz, Petit, Christine, Regazzi, Romano · 2003 · Molecular Biology of the Cell
110. NAADP
     Roser Masgrau, Grant C. Churchill, Anthony John Morgan · 2003 · Current Biology
111. Endoplasmic reticulum calcium store regulates membrane potential in mouse islet beta-cells.
     Jennings F. Worley, Maggie S. McIntyre, B. Spencer, Robert J. Mertz, Michael Wm. Roe, Iain D. Dukes · 1994 · Journal of Biological Chemistry
112. Increased Insulin Secretion and Glucose Tolerance in Mice Lacking Islet Amyloid Polypeptide (Amylin)
     Gebre-Medhin, Samuel, Mulder, Hindrik, Pekny, Milos, Westermark, Gunilla, Törnell, Jan, Westermark, Per, Sundler, Frank, Ahrén, Bo, Betsholtz, Christer · 1998 · Biochemical and Biophysical Research Communications
113. Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR
     Guo, Jing Hui, Chen, Hui, Ruan, Ye Chun, Zhang, Xue Lian, Zhang, Xiao Hu, Fok, Kin Lam, Tsang, Lai Ling, Yu, Mei Kuen, Huang, Wen Qing, Sun, Xiao et al. · 2014 · Nature Communications
114. Involvement of conventional kinesin in glucose-stimulated secretory granule movements and exocytosis in clonal pancreatic β-cells
     Varadi, Aniko, Ainscow, Edward K., Allan, Victoria J., Rutter, Guy A. · 2002 · Journal of Cell Science
115. Critical Reduction in β-Cell Mass Results in Two Distinct Outcomes over Time
     D. Ross Laybutt, Mariela Glandt, Gang Xu, Yu Bai Ahn, Nitin Trivedi, Susan Bonner‐Weir, Gordon C. Weir · 2003 · Journal of Biological Chemistry
116. Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion
     Gheni, Ghupurjan, Ogura, Masahito, Iwasaki, Masahiro, Yokoi, Norihide, Minami, Kohtaro, Nakayama, Yasumune, Harada, Kazuo, Hastoy, Benoit, Wu, Xichen, Takahashi, Harumi et al. · 2014 · Cell Reports
117. Electrophysiology of Islet Cells
     Drews, Gisela, Krippeit-Drews, Peter, Düfer, Martina · 2010 · Advances in Experimental Medicine and Biology
118. Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory Granules
     Hoppa, Michael B., Collins, Stephan, Ramracheya, Reshma, Hodson, Leanne, Amisten, Stefan, Zhang, Quan, Johnson, Paul, Ashcroft, Frances M., Rorsman, Patrik · 2009 · Cell Metabolism
119. cAMP sensor Epac as a determinant of ATP‐sensitive potassium channel activity in human pancreatic β cells and rat INS‐1 cells
     Guoxin Kang, Oleg G. Chepurny, Brian Malester, Michael J. Rindler, Holger Rehmann, Johannes L. Bos, Frank Schwede, William A. Coetzee, George G. Holz · 2006 · The Journal of Physiology
120. Distinct Initial SNARE Configurations Underlying the Diversity of Exocytosis
     Kasai, Haruo, Takahashi, Noriko, Tokumaru, Hiroshi · 2012 · Physiological Reviews
121. Physical Exercise-Induced Hyperinsulinemic Hypoglycemia Is an Autosomal-Dominant Trait Characterized by Abnormal Pyruvate-Induced Insulin Release
     Timo Otonkoski, Nina Kaminen‐Ahola, Jarkko Ustinov, Risto Lapatto, Thomas Meißner, Ertan Mayatepek, Juha Kere, Ilkka Sipilä · 2003 · Diabetes
122. Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet
     J. Molina, R. Rodriguez-Diaz, A. Fachado, M. C. Jacques-Silva, Per-Olof Berggren, A. Caicedo · 2014 · Diabetes
123. Insulin Activates ATP-Sensitive K+ Channels in Pancreatic β-Cells Through a Phosphatidylinositol 3-Kinase–Dependent Pathway
     Farrukh A. Khan, Paulette B. Goforth, Min Zhang, Leslie S. Satin · 2001 · Diabetes
124. Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance
     Eunjung Lee, Dae Young Jung, Jong Hun Kim, Payal R. Patel, Xiaodi Hu, Yongjin Lee, Yoshihiro Azuma, Hsun-Fan Wang, Nicholas Tsitsilianos, Umber Shafiq et al. · 2015 · The FASEB Journal
125. Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR)
     Daliang Li, Shiuhwei Chen, Elisa A. Bellomo, Andrei I. Tarasov, Callan Kaut, Guy A. Rutter, Wen-Hong Li · 2011 · Proceedings of the National Academy of Sciences
126. Glucose-Induced Amplitude Regulation of Pulsatile Insulin Secretion From Individual Pancreatic Islets
     Bergsten, Peter, Hellman, Bo · 1993 · Diabetes
127. Post-priming actions of ATP on Ca 2+ -dependent exocytosis in pancreatic beta cells
     Noriko K. Takahashi, Takashi Kadowaki, Yoshio Yazaki, Graham C. R. Ellis‐Davies, Yasushi Miyashita, Haruo Kasai · 1999 · Proceedings of the National Academy of Sciences
128. Metabotropic glutamate and GABAB receptors contribute to the modulation of glucose-stimulated insulin secretion in pancreatic beta cells
     Nicola Brice, Anikó Váradi, S. J. H. Ashcroft, Elek Molnár · 2002 · Diabetologia
129. Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic β -cells
     Smith, Paul A., Rorsman, Patrik, Ashcroft, Frances M. · 1989 · Nature
130. Patch‐clamp characterisation of somatostatin‐secreting δ‐cells in intact mouse pancreatic islets
     Sven Göpel, T. Kanno, Sebastian Barg, Patrik Rorsman · 2000 · The Journal of Physiology
131. Electrogenic arginine transport mediates stimulus‐secretion coupling in mouse pancreatic beta‐cells.
     Smith, P A, Sakura, H, Coles, B, Gummerson, N, Proks, P, Ashcroft, F M · 1997 · The Journal of Physiology
132. SNARE-complex disassembly by NSF follows synaptic-vesicle fusion
     Littleton, J. Troy, Barnard, Richard J. O., Titus, Steven A., Slind, Jessica, Chapman, Edwin R., Ganetzky, Barry · 2001 · Proceedings of the National Academy of Sciences
133. A Fresh View of Glycolysis and Glucokinase Regulation: History and Current Status*
     S. Lenzen · 2014 · Journal of Biological Chemistry
134. Neural regulation of pancreatic islet cell mass and function
     Thorens, B. · 2014 · Diabetes, Obesity and Metabolism
135. Selective nucleotide-release from dense-core granules in insulin-secreting cells
     Obermüller, Stefanie, Lindqvist, Anders, Karanauskaite, Jovita, Galvanovskis, Juris, Rorsman, Patrik, Barg, Sebastian · 2005 · Journal of Cell Science
136. CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
     Anna Edlund, Jonathan L.S. Esguerra, Anna Wendt, Malin Flodström‐Tullberg, Lena Eliasson · 2014 · BMC Medicine
137. A nonclassical estrogen membrane receptor triggers rapid differential actions in the endocrine pancreas.
     A. Ropero, Bernat Soria, A. Nadal · 2002 · Molecular Endocrinology
138. Electrical coupling between cells in islets of langerhans from mouse
     Eddlestone, G. T., Gonçalves, A., Bangham, J. A., Rojas, E. · 1984 · The Journal of Membrane Biology
139. Action Potential-induced Quantal Secretion of Catecholamines from Rat Adrenal Chromaffin Cells
     Zhuan Zhou, Stanley Misler · 1995 · Journal of Biological Chemistry
140. Activation of Ca2+-Dependent K+ Channels Contributes to Rhythmic Firing of Action Potentials in Mouse Pancreatic β Cells
     Göpel, Sven O., Kanno, Takahiro, Barg, Sebastian, Eliasson, Lena, Galvanovskis, Juris, Renström, Erik, Rorsman, Patrik · 1999 · The Journal of General Physiology
141. Are we overestimating the loss of beta cells in type 2 diabetes?
     Marselli, Lorella, Suleiman, Mara, Masini, Matilde, Campani, Daniela, Bugliani, Marco, Syed, Farooq, Martino, Luisa, Focosi, Daniele, Scatena, Fabrizio, Olimpico, Francesco et al. · 2014 · Diabetologia
142. Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets
     Ramracheya, Reshma, Ward, Caroline, Shigeto, Makoto, Walker, Jonathan N., Amisten, Stefan, Zhang, Quan, Johnson, Paul R., Rorsman, Patrik, Braun, Matthias · 2010 · Diabetes
143. Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells
     Rorsman, Patrik, Bokvist, Krister, Ämmälä, Carina, Arkhammar, Per, Berggren, Per-Olof, Larsson, Olof, Wåhlander, Karin · 1991 · Nature
144. Properties of single potassium channels modulated by glucose in rat pancreatic beta‐cells.
     Ashcroft, F M, Ashcroft, S J, Harrison, D E · 1988 · The Journal of Physiology
145. Suppression of Insulin Release by Galanin and Somatostatin Is Meditated by a G-protein
     Thomas Nilsson, Per O. G. Arkhammar, Patrik Rorsman, Per‐Olof Berggren · 1989 · Journal of Biological Chemistry
146. Inhibition or Ablation of p21-activated Kinase (PAK1) Disrupts Glucose Homeostatic Mechanisms in Vivo
     Zhanxiang Wang, Eunjin Oh, D. Wade Clapp, Jonathan Chernoff, Debbie C. Thurmond · 2011 · Journal of Biological Chemistry
147. Glucose‐ and arginine‐induced insulin secretion by human pancreatic β‐cells: the role of HERG K ⁺ channels in firing and release
     Rosati, Barbara, Marchetti, Piero, Crociani, Olivia, Lecchi, Marzia, Lupi, Roberto, Arcangeli, Annarosa, Olivotto, Massimo, Wanke, Enzo · 2000 · The FASEB Journal
148. Mechanism of Cloned ATP-sensitive Potassium Channel Activation by Oleoyl-CoA
     Gribble, Fiona M., Proks, Peter, Corkey, Barbara E., Ashcroft, Frances M. · 1998 · Journal of Biological Chemistry
149. Release of small transmitters through kiss-and-run fusion pores in rat pancreatic β cells
     Patrick E. MacDonald, Matthias Braun, Juris Galvanovskis, Patrik Rorsman · 2006 · Cell Metabolism
150. MicroRNAs: 'ribo-regulators' of glucose homeostasis
     Benoit R. Gauthier, Claes B. Wollheim · 2006 · Nature Medicine
151. SLC2A2 mutations can cause neonatal diabetes, suggesting GLUT2 may have a role in human insulin secretion
     Francis H. Sansbury, Sarah Elizabeth Flanagan, Jayne Houghton, F. L. Shuixian Shen, Aisha Al Senani, Abdelhadi M. Habeb, Mohamed Ahmed Abdullah, Ariana Kariminejad, Sian Ellard, Andrew Tym Hattersley · 2012 · Diabetologia
152. MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets
     Dagmar Klein, Ryosuke Misawa, Valia Bravo-Egaña, Nancy Vargas, Samuel Rosero, Julieta Piroso, Hirohito Ichii, Oliver Umland, Jiang Zhijie, Nicholas F. Tsinoremas et al. · 2013 · PLoS ONE
153. Critical Role of Gap Junction Coupled KATP Channel Activity for Regulated Insulin Secretion
     Rocheleau, Jonathan V, Remedi, Maria S, Granada, Butch, Head, W. Steven, Koster, Joseph C, Nichols, Colin G, Piston, David W · 2006 · PLoS Biology
154. Effects of leptin and adiponectin on pancreatic β-cell function
     Yong‐ho Lee, Faidon Magkos, Christos Socrates Mantzoros, Eun Seok Kang · 2011 · Metabolism
155. Inhibition of Cholesterol Biosynthesis Impairs Insulin Secretion and Voltage-Gated Calcium Channel Function in Pancreatic β-Cells
     Xia, Fuzhen, Xie, Li, Mihic, Anton, Gao, Xiaodong, Chen, Yi, Gaisano, Herbert Y., Tsushima, Robert G. · 2008 · Endocrinology
156. Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site
     Gandasi, Nikhil R., Barg, Sebastian · 2014 · Nature Communications
157. Regulated Exocytosis of GABA-containing Synaptic-like Microvesicles in Pancreatic β-cells
     Braun, Matthias, Wendt, Anna, Birnir, Bryndis, Broman, Jonas, Eliasson, Lena, Galvanovskis, Juris, Gromada, Jesper, Mulder, Hindrik, Rorsman, Patrik · 2004 · The Journal of General Physiology
158. Effect of donor age on function of isolated human islets
     Ihm, Sung-Hee, Matsumoto, Ippei, Sawada, Toshiya, Nakano, Masahiko, Zhang, Hui J., Ansite, Jeffrey D., Sutherland, David E.R., Hering, Bernhard J. · 2006 · Diabetes
159. Inhibition of Phosphatases and Increased Ca 2+ Channel Activity by Inositol Hexakisphosphate
     Olof Larsson, Christopher J. Barker, Åke Sjöholm, Håkan Carlqvist, Robert Hall Michell, Alejandro M. Bertorello, Thomas Nilsson, Richard E. Honkanen, Georg W. Mayr, Jean Zwiller et al. · 1997 · Science
160. Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM
     G. M. Martin, Balamurugan Kandasamy, F. DiMaio, C. Yoshioka, S. Shyng · 2017 · eLife
161. Inositol trisphosphate-dependent periodic activation of a Ca2+-activated K+ conductance in glucose-stimulated pancreatic β-cells
     Carina Ämmälä, Olof Larsson, Per‐Olof Berggren, Krister B. Bokvist, Lisa Juntti‐Berggren, Henrik Kindmark, Patrik Rorsman · 1991 · Nature
162. Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells
     Colin A. Leech, Igor Dzhura, Oleg G. Chepurny, Guoxin Kang, Frank Schwede, Hans‐Gottfried Genieser, George G. Holz · 2011 · Progress in Biophysics and Molecular Biology
163. Molecular mechanisms of mitochondrial diabetes (MIDD)
     J. Antonie Maassen, George M. C. Janssen, Leen M. ‘t Hart · 2005 · Annals of Medicine
164. The Influence of γ-Aminobutyric Acid on Hormone Release by the Mouse and Rat Endocrine Pancreas*
     GILON, P., BERTRAND, G., LOUBATIÉRES-MARIANI, M. M., REMACLE, C., HENQUIN, J. C. · 1991 · Endocrinology
165. ATP-gated P2X ₃ receptors constitute a positive autocrine signal for insulin release in the human pancreatic β cell
     Jacques-Silva, M. Caroline, Correa-Medina, Mayrin, Cabrera, Over, Rodriguez-Diaz, Rayner, Makeeva, Natalia, Fachado, Alberto, Diez, Juan, Berman, Dora M., Kenyon, Norma S., Ricordi, Camillo et al. · 2010 · Proceedings of the National Academy of Sciences
166. Pancreatic β-Cell Protein Granuphilin Binds Rab3 and Munc-18 and Controls Exocytosis
     Coppola, Thierry, Frantz, Christian, Perret-Menoud, Véronique, Gattesco, Sonia, Hirling, Harald, Regazzi, Romano · 2002 · Molecular Biology of the Cell
167. PIP2-Binding Site in Kir Channels: Definition by Multiscale Biomolecular Simulations
     Phillip James Stansfeld, Richard J. Hopkinson, Frances Mary Ashcroft, Mark S.P. Sansom · 2009 · Biochemistry
168. Deletion of the von Hippel–Lindau gene in pancreatic β cells impairs glucose homeostasis in mice
     Cantley, James, Selman, Colin, Shukla, Deepa, Abramov, Andrey Y., Forstreuter, Frauke, Esteban, Miguel A., Claret, Marc, Lingard, Steven J., Clements, Melanie, Harten, Sarah K. et al. · 2008 · Journal of Clinical Investigation
169. The Ca2+ Affinity of Synaptotagmin 1 Is Markedly Increased by a Specific Interaction of Its C2B Domain with Phosphatidylinositol 4,5-Bisphosphate
     Anand Radhakrishnan, A. Stein, R. Jahn, D. Fasshauer · 2009 · Journal of Biological Chemistry
170. Syntaxin 1A Binds to the Cytoplasmic C Terminus of Kv2.1 to Regulate Channel Gating and Trafficking
     Leung, Yuk M., Kang, Youhou, Gao, Xiaodong, Xia, Fuzhen, Xie, Huanli, Sheu, Laura, Tsuk, Sharon, Lotan, Ilana, Tsushima, Robert G., Gaisano, Herbert Y. · 2003 · Journal of Biological Chemistry
171. A novel approach to in situ characterization of pancreatic β-cells
     Stephan Speier, Marjan Slak Rupnik · 2003 · Pflügers Archiv - European Journal of Physiology
172. The fusion pores of Ca2+-triggered exocytosis
     Meyer B. Jackson, Edwin R. Chapman · 2008 · Nature Structural & Molecular Biology
173. Similar reduction of first- and second-phase B-cell responses at three different glucose levels in type II diabetes and the effect of gliclazide therapy
     Hosker, John P., Rudenski, Aram S., Burnett, Melanie A., Matthews, David R., Turner, Robert C. · 1989 · Metabolism
174. Insulin Secretory Deficiency and Glucose Intolerance in Rab3A Null Mice
     Kazuro Yaekura, Richard Julyan, Barton L. Wicksteed, Lori B. Hays, Cristina Alarcón, Scott Sommers, Vincent Poitout, Denis G. Baskin, Yong Wang, Louis H. Philipson et al. · 2003 · Journal of Biological Chemistry
175. Mitochondrial function and insulin secretion
     Pierre Maechler · 2013 · Molecular and Cellular Endocrinology
176. Glucagon-Like Peptide I Increases Cytoplasmic Calcium in Insulin-Secreting βTC3-Cells by Enhancement of Intracellular Calcium Mobilization
     Gromada, Jesper, Dissing, Steen, Bokvist, Krister, Renström, Erik, Frøkjær-Jensen, Jørgen, Wulff, Birgitte S, Rorsman, Patrik · 1995 · Diabetes
177. The stimulus secretion coupling of glucose-induced insulin release: XXVII. Effect of glucose on K+ fluxes in isolated islets
     Malaisse, W. J., Boschero, A. C., Kawazu, S., Hutton, J. C. · 1978 · Pfl�gers Archiv European Journal of Physiology
178. Reduction in Voltage-Gated K+ Currents in Primary Cultured Rat Pancreatic β-Cells by Linoleic Acids
     Feng, Dan Dan, Luo, Ziqiang, Roh, Sang-gun, Hernandez, Maria, Tawadros, Neveen, Keating, Damien J., Chen, Chen · 2006 · Endocrinology
179. Requirement for the L-type Ca2+ channel α1D subunit in postnatal pancreatic β cell generation
     Yoon Namkung, Nataliya Skrypnyk, Myung-jin Jeong, Taehoon Lee, Myung‐Shik Lee, Hyung‐Lae Kim, Hemin R. Chin, Pann‐Ghill Suh, Sung-Sook Kim, Hee‐Sup Shin · 2001 · Journal of Clinical Investigation
180. Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells
     Brereton, Melissa F., Rohm, Maria, Shimomura, Kenju, Holland, Christian, Tornovsky-Babeay, Sharona, Dadon, Daniela, Iberl, Michaela, Chibalina, Margarita V., Lee, Sheena, Glaser, Benjamin et al. · 2016 · Nature Communications
181. Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes
     Andersson, Sofia A., Olsson, Anders H., Esguerra, Jonathan L.S., Heimann, Emilia, Ladenvall, Claes, Edlund, Anna, Salehi, Albert, Taneera, Jalal, Degerman, Eva, Groop, Leif et al. · 2012 · Molecular and Cellular Endocrinology
182. Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in white caucasian subjects or evidence of abnormal function when expressed in vitro
     Sakura, H., Wat, N., Horton, V., Millns, H., Turner, R. C., Ashcroft, F. M. · 1996 · Diabetologia
183. The SNAREs vti1a and vti1b have distinct localization and SNARE complex partners
     Vera Kreykenbohm, Dirk Wenzel, Wolfram Antonin, Vadim Atlachkine, Gabriele Fischer von Mollard · 2002 · European Journal of Cell Biology
184. The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic β‐cell line
     Leigh Anne Swayne, Alexandre Mezghrani, Annie Varrault, Jean Chemin, Gyslaine Bertrand, Stéphane Dalle, Emmanuel Bourinet, Philippe Lory, Richard J. Miller, Joël Nargeot et al. · 2009 · EMBO Reports
185. A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse
     Alexander F. Jeans, Peter L. Oliver, Reuben Johnson, Marco Capogna, Jenny Vikman, Zoltán Molnár, Arran Babbs, Christopher J. Partridge, Albert A. Salehi, Martin Bengtsson et al. · 2007 · Proceedings of the National Academy of Sciences
186. Protein Kinase A-Dependent Stimulation of Exocytosis in Mouse Pancreatic β-Cells by Glucose-Dependent Insulinotropic Polypeptide
     Wei‐Guang Ding, Jesper Gromada · 1997 · Diabetes
187. Somatostatin inhibits exocytosis in rat pancreatic α‐cells by G _i2 ‐dependent activation of calcineurin and depriming of secretory granules
     Gromada, Jesper, Høy, Marianne, Buschard, Karsten, Salehi, Albert, Rorsman, Patrik · 2001 · The Journal of Physiology
188. A Highly Ca2+-sensitive Pool of Granules Is Regulated by Glucose and Protein Kinases in Insulin-secreting INS-1 Cells
     Yan Yang, Kevin D. Gillis · 2004 · The Journal of General Physiology
189. Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the <i>KCNQ1</i> Locus From Temporal Changes in Imprinting Status in Human Islets
     Travers, Mary E., Mackay, Deborah J.G., Dekker Nitert, Marloes, Morris, Andrew P., Lindgren, Cecilia M., Berry, Andrew, Johnson, Paul R., Hanley, Neil, Groop, Leif C., McCarthy, Mark I. et al. · 2013 · Diabetes
190. γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes
     Taneera, J., Jin, Z., Jin, Y., Muhammed, S. J., Zhang, E., Lang, S., Salehi, A., Korsgren, O., Renström, E., Groop, L. et al. · 2012 · Diabetologia
191. An ATP-Sensitive Cl− Channel Current That Is Activated by Cell Swelling, cAMP, and Glyburide in Insulin-Secreting Cells
     Kinard, Tracie A, Satin, Leslie S · 1995 · Diabetes
192. Glucose-induced changes in cytosolic ATP content in pancreatic islets
     Malaisse, Willy J., Sener, Abdullah · 1987 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
193. Properties of the Ca-activated K+ channel in pancreatic β-cells
     Illani J. Atwater, Luı́s M. Rosário, Eduardo Rojas · 1983 · Cell Calcium
194. Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes
     MacDonald, M. J., Longacre, M. J., Langberg, E.-C., Tibell, A., Kendrick, M. A., Fukao, T., Ostenson, C.-G. · 2009 · Diabetologia
195. Glucose-Dependent Granule Docking Limits Insulin Secretion and Is Decreased in Human Type 2 Diabetes
     Gandasi, Nikhil R., Yin, Peng, Omar-Hmeadi, Muhmmad, Ottosson Laakso, Emilia, Vikman, Petter, Barg, Sebastian · 2018 · Cell Metabolism
196. Removal of Ca2+ Channel β3 Subunit Enhances Ca2+ Oscillation Frequency and Insulin Exocytosis
     Berggren, Per-Olof, Yang, Shao-Nian, Murakami, Manabu, Efanov, Alexander M., Uhles, Sabine, Köhler, Martin, Moede, Tilo, Fernström, Andreas, Appelskog, Ioulia B., Aspinwall, Craig A. et al. · 2004 · Cell
197. The first C2 domain of synaptotagmin is required for exocytosis of insulin from pancreatic β‐cells: action of synaptotagmin at low micromolar calcium
     Jochen Lang, Mitsunori Fukuda, Hui Zhang, Katsuhiko Mikoshiba, Claes B. Wollheim · 1997 · The EMBO Journal
198. Functional neuronal ionotropic glutamate receptors are expressed in the non-neuronal cell line MIN6.
     Gonoi, T., Mizuno, N., Inagaki, N., Kuromi, H., Seino, Y., Miyazaki, J., Seino, S. · 1994 · Journal of Biological Chemistry
199. Synapsin regulation of vesicle organization and functional pools.
     M. Bykhovskaia · 2011 · Seminars in Cell and Developmental Biology
200. Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors
     Gromada, J., Ding, Wei-Guang, Barg, Sebastian, Renström, Erik, Rorsman, Patrik · 1997 · Pfl�gers Archiv European Journal of Physiology