Brown Adipose Tissue: Function and Physiological Significance

Cited by (1,061)

Items 1,001–1,061 of 1,061

1. Activin E controls energy homeostasis in both Brown and white adipose tissues as a hepatokine
   Hashimoto, Osamu, Funaba, Masayuki, Sekiyama, Kazunari, Doi, Satoru, Shindo, Daichi, Satoh, Ryo, Itoi, Hiroshi, Oiwa, Hiroaki, Morita, Masahiro, Suzuki, Chisato et al. · 2018 · Cell Reports
2. Modeling insulin resistance in rodents by alterations in diet: What have high-fat and high-calorie diets revealed?
   Small, Lewin, Brandon, Amanda E., Turner, Nigel, Cooney, Gregory J. · 2018 · American Journal of Physiology-Endocrinology and Metabolism
3. Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge
   Lu, Yuan, Fujioka, Hisashi, Joshi, Dinesh, Li, Qiaoyuan, Sangwung, Panjamaporn, Hsieh, Paishiun, Zhu, Jiyun, Torio, Jose, Sweet, David, Wang, Lan et al. · 2018 · Scientific Reports
4. Metabolic consequences of chronic sleep restriction in rats: Changes in body weight regulation and energy expenditure
   Barf, R.P., Van Dijk, G., Scheurink, A.J.W., Hoffmann, K., Novati, A., Hulshof, H.J., Fuchs, E., Meerlo, P. · 2012 · Physiology & Behavior
5. The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation
   Wang, Qiuyu, Sharma, Vishal P., Shen, Hong, Xiao, Yuanyuan, Zhu, Qi, Xiong, Xuelian, Guo, Liang, Jiang, Lin, Ohta, Kunimasa, Li, Siming et al. · 2019 · Nature Metabolism
6. Home alone: a systematic review and meta‐analysis on the effects of individual housing on body weight, food intake and visceral fat mass in rodents
   Schipper, L., Harvey, L., van der Beek, E. M., van Dijk, G. · 2018 · Obesity Reviews
7. Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system
   Cheng, Ying, Zhang, Qian, Meng, Qingshu, Xia, Tingting, Huang, Zhiying, Wang, Chunxia, Liu, Bin, Chen, Shanghai, Xiao, Fei, Du, Ying et al. · 2011 · Molecular Endocrinology
8. Receptor for advanced glycation end-products (RAGE) regulation of adiposity and adiponectin is associated with atherogenesis in apoE-deficient mouse
   Ueno, Hiroki, Koyama, Hidenori, Shoji, Takuhito, Monden, Masayo, Fukumoto, Shinya, Tanaka, Shinji, Otsuka, Yoshiko, Mima, Yohei, Morioka, Tomoaki, Mori, Katsuhito et al. · 2010 · Atherosclerosis
9. Acetaminophen: Antipyretic or hypothermic in mice? In either case, PGHS-1b (COX-3) is irrelevant
   Li, Shuxin, Dou, Wenkai, Tang, Ying, Goorha, Sarita, Ballou, Leslie R., Blatteis, Clark M. · 2008 · Prostaglandins & Other Lipid Mediators
10. Central inhibitory effects on feeding induced by the adipo-myokine irisin
    Ferrante, Claudio, Orlando, Giustino, Recinella, Lucia, Leone, Sheila, Chiavaroli, Annalisa, Di Nisio, Chiara, Shohreh, Rugia, Manippa, Fabio, Ricciuti, Adriana, Vacca, Michele et al. · 2016 · European Journal of Pharmacology
11. Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis
    Paulo, Esther, Wu, Dongmei, Wang, Yangmeng, Zhang, Yun, Wu, Yixuan, Swaney, Danielle L., Soucheray, Margaret, Jimenez-Morales, David, Chawla, Ajay, Krogan, Nevan J. et al. · 2018 · Scientific Reports
12. Liraglutide induces beige fat development and promotes mitochondrial function in diet induced obesity mice partially through AMPK-SIRT-1-PGC1-α cell signaling pathway
    Zhou, Joseph, Poudel, Anil, Chandramani-Shivalingappa, Prashanth, Xu, Biao, Welchko, Ryan, Li, Lixin · 2019 · Endocrine
13. Uncoupling protein 1 expression in murine skeletal muscle increases AMPK activation, glucose turnover, and insulin sensitivity in vivo
    Neschen, Susanne, Katterle, Yvonne, Richter, Julia, Augustin, Robert, Scherneck, Stephan, Mirhashemi, Farshad, Schürmann, Annette, Joost, Hans-Georg, Klaus, Susanne · 2008 · Physiological Genomics
14. FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes
    Chen, Mark Z., Chang, Joshua C., Zavala-Solorio, Jose, Kates, Lance, Thai, Minh, Ogasawara, Annie, Bai, Xiaobo, Flanagan, Sean, Nunez, Victor, Phamluong, Khanhky et al. · 2017 · Molecular Metabolism
15. Sympathetic Nerve Activity Maintains an Anti-Inflammatory State in Adipose Tissue in Male Mice by Inhibiting TNF-α Gene Expression in Macrophages
    Tang, Lijun, Okamoto, Shiki, Shiuchi, Tetsuya, Toda, Chitoku, Takagi, Kazuyo, Sato, Tatsuya, Saito, Kumiko, Yokota, Shigefumi, Minokoshi, Yasuhiko · 2015 · Endocrinology
16. Cold Tolerance in Hypothyroid Rabbits: Role of Skeletal Muscle Mitochondria and Sarcoplasmic Reticulum Ca2+ ATPase Isoform 1 Heat Production
    Arruda, Ana Paula, Ketzer, Luisa A., Nigro, Mariana, Galina, Antonio, Carvalho, Denise P., de Meis, Leopoldo · 2008 · Endocrinology
17. Insights into brown adipose tissue evolution and function from non-model organisms
    Jastroch, Martin, Oelkrug, Rebecca, Keipert, Susanne · 2018 · Journal of Experimental Biology
18. MicroRNAs in brown and beige fat
    Goody, Deborah, Pfeifer, Alexander · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
19. The role of autophagy in brown and beige adipose tissue plasticity
    Cairó, Montserrat, Villarroya, Joan · 2020 · Journal of Physiology and Biochemistry
20. Sexual Dimorphic Metabolic and Cognitive Responses of C57BL/6 Mice to Fisetin or Dasatinib and Quercetin Cocktail Oral Treatment
    Fang, Yimin, Medina, David, Stockwell, Robert, McFadden, Sam, Quinn, Kathleen, Peck, Mackenzie R., Bartke, Andrzej, Hascup, Kevin N., Hascup, Erin R. · 2021
21. Lipoatrophy and metabolic disturbance in mice with adipose-specific deletion of kindlin-2
    Gao, Huanqing, Guo, Yuxi, Yan, Qinnan, Yang, Wei, Li, Ruxuan, Lin, Simin, Bai, Xiaochun, Liu, Chuanju, Chen, Di, Cao, Huiling et al. · 2019 · JCI Insight
22. Whole Genome Scan and Selection Signatures for Climate Adaption in Yanbian Cattle
    Shen, Jiafei, Hanif, Quratulain, Cao, Yang, Yu, Yongsheng, Lei, Chuzhao, Zhang, Guoliang, Zhao, Yumin · 2020 · Frontiers in Genetics
23. Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic review
    Dinas, Petros C., Lahart, Ian M., Timmons, James A., Svensson, Per-Arne, Koutedakis, Yiannis, Flouris, Andreas D., Metsios, George S. · 2017 · F1000Research
24. Expression of UCP3 in CHO cells does not cause uncoupling, but controls mitochondrial activity in the presence of glucose
    Mozo, Julien, Ferry, Gilles, Studeny, Aurélie, Pecqueur, Claire, Rodriguez, Marianne, Boutin, Jean A., Bouillaud, Frédéric · 2006 · Biochemical Journal
25. Hyperthermic reactions induced by orexin A: role of the ventromedial hypothalamus
    Monda, M., Viggiano, An., Viggiano, Al., Viggiano, E., Lanza, A., De Luca, V. · 2005 · European Journal of Neuroscience
26. Altered biodistribution on FDG-PET with emphasis on brown fat and insulin effect
    Cohade, Christian · 2010 · Seminars in Nuclear Medicine
27. Anti-diabetic effects of GLP1 analogs are mediated by thermogenic interleukin-6 signaling in adipocytes
    Gutierrez, Absalon D., Gao, Zhanguo, Hamidi, Vala, Zhu, Liang, Saint Andre, Karla Bermudez, Riggs, Kayla, Ruscheinsky, Monika, Wang, Hongyu, Yu, Yongmei, Miller, Charles et al. · 2022 · Cell Reports Medicine
28. Is Glucagon Receptor Activation the Thermogenic Solution for Treating Obesity?
    Conceição-Furber, Ellen, Coskun, Tamer, Sloop, Kyle W., Samms, Ricardo J. · 2022 · Frontiers in Endocrinology
29. Looking on the “brite” side exercise-induced browning of white adipose tissue
    Townsend, Logan K., Wright, David C. · 2019 · Pflügers Archiv - European Journal of Physiology
30. Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-β Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders
    Pervin, Shehla, Reddy, Srinivasa T., Singh, Rajan · 2021 · Frontiers in Endocrinology
31. A Genetic Model to Study the Contribution of Brown and Brite Adipocytes to Metabolism
    Challa, Tenagne D., Dapito, Dianne H., Kulenkampff, Elisabeth, Kiehlmann, Elke, Moser, Caroline, Straub, Leon, Sun, Wenfei, Wolfrum, Christian · 2020 · Cell Reports
32. Cold acclimation enhances UCP1 content, lipolysis, and triacylglycerol resynthesis, but not mitochondrial uncoupling and fat oxidation, in rat white adipocytes
    Sepa-Kishi, Diane M., Jani, Shailee, Da Eira, Daniel, Ceddia, Rolando B. · 2019 · American Journal of Physiology-Cell Physiology
33. Exercise-mediated effects on white and brown adipose tissue plasticity and metabolism
    Sepa-Kishi, Diane M., Ceddia, Rolando B. · 2016 · Exercise and Sport Sciences Reviews
34. Regulation of Energy Balance via BDNF Expressed in Nonparaventricular Hypothalamic Neurons
    Yang, Haili, An, Juan Ji, Sun, Chao, Xu, Baoji · 2016 · Molecular Endocrinology
35. The emerging neuroprotective role of mitochondrial uncoupling protein-2 in traumatic brain injury
    Normoyle, Kieran P., Kim, Miri, Farahvar, Arash, Llano, Daniel, Jackson, Kevin, Wang, Huan · 2015 · Translational Neuroscience
36. Dietary n-3 long-chain polyunsaturated fatty acids upregulate energy dissipating metabolic pathways conveying anti-obesogenic effects in mice
    Worsch, Stefanie, Heikenwalder, Mathias, Hauner, Hans, Bader, Bernhard L. · 2018 · Nutrition & Metabolism
37. Administration of eicosapentaenoic and docosahexaenoic acids may improve the remodeling and browning in subcutaneous white adipose tissue and thermogenic markers in brown adipose tissue in mice
    Bargut, Thereza Cristina Lonzetti, Martins, Fabiane Ferreira, Santos, Larissa Pereira, Aguila, Marcia Barbosa, Mandarim-de-Lacerda, Carlos A. · 2019 · Molecular and Cellular Endocrinology
38. ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity
    Sparks, Lauren M., Gemmink, Anne, Phielix, Esther, Bosma, Madeleen, Schaart, Gert, Moonen-Kornips, Esther, Jörgensen, Johanna A., Nascimento, Emmani B. M., Hesselink, Matthijs K. C., Schrauwen, Patrick et al. · 2016 · Diabetologia
39. Adrenergically stimulated blood flow in brown adipose tissue is not dependent on thermogenesis
    Abreu-Vieira, Gustavo, Hagberg, Carolina E., Spalding, Kirsty L., Cannon, Barbara, Nedergaard, Jan · 2015 · American Journal of Physiology-Endocrinology and Metabolism
40. Role of Adipokines in Sarcopenia
    Lu, Wenhao, Feng, Wenjie, Lai, Jieyu, Yuan, Dongliang, Xiao, Wenfeng, Li, Yusheng · 2023 · Chinese Medical Journal
41. Metabolic Adaptations to Weight Loss: A Brief Review
    Martínez-Gómez, Mario G., Roberts, Brandon M. · 2022 · Journal of Strength & Conditioning Research
42. Overexpression of Constitutively Active PKG‐I Protects Female, But Not Male Mice From Diet‐Induced Obesity
    Nikolic, Dejan M., Li, Yanzhang, Liu, Shu, Wang, Shuxia · 2011 · Obesity
43. Validation of bioelectrical impedance analysis for body composition assessment in children with obesity aged 8-14y
    Gutiérrez-Marín, Desirée, Escribano, Joaquin, Closa-Monasterolo, Ricardo, Ferré, Natalia, Venables, Michelle, Singh, Priya, Wells, Jonathan CK., Muñoz-Hernando, Judit, Zaragoza-Jordana, Marta, Gispert-Llauradó, Mariona et al. · 2021 · Clinical Nutrition
44. Prenatal exposure to ambient fine particulate matter induces dysregulations of lipid metabolism in adipose tissue in male offspring
    Xie, Peisi, Zhao, Chao, Huang, Wei, Yong, Ting, Chung, Arthur C.K., He, Kaiwu, Chen, Xiangfeng, Cai, Zongwei · 2019 · Science of The Total Environment
45. Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic
    Zekri, Yanis, Flamant, Frédéric, Gauthier, Karine · 2021 · Cells
46. Adapting to the cold: A role for endogenous fibroblast growth factor 21 in thermoregulation?
    Klein Hazebroek, Marlou, Keipert, Susanne · 2020 · Frontiers in Endocrinology
47. Identification of serine phosphorylation in mitochondrial uncoupling protein 1
    Carroll, Audrey M., Porter, Richard K., Morrice, Nick A. · 2008 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
48. Brown Adipose Tissue and Browning Agents: Irisin and FGF21 in the Development of Obesity in Children and Adolescents
    Pyrżak, B., Demkow, U., Kucharska, A. M. · 2015 · Advances in experimental medicine and biology
49. IDOL regulates systemic energy balance through control of neuronal VLDLR expression
    Lee, Stephen D., Priest, Christina, Bjursell, Mikael, Gao, Jie, Arneson, Douglas V., Ahn, In Sook, Diamante, Graciel, van Veen, J. Edward, Massa, Megan G., Calkin, Anna C. et al. · 2019 · Nature Metabolism
50. Cardiovascular and Sympathetic Effects of Disrupting Tyrosine 985 of the Leptin Receptor
    Harlan, Shannon M., Morgan, Donald A., Dellsperger, David J., Myers, Martin G., Mark, Allyn L., Rahmouni, Kamal · 2011 · Hypertension
51. Cold exposure induces nuclear translocation of CRTC3 in brown adipose tissue
    Xu, Ziye, Liu, Jiaqi, You, Wenjing, Wang, Yizhen, Shan, Tizhong · 2019 · Journal of Cellular Biochemistry
52. Melatonin Supplementation and Anthropometric Indices: A Randomized Double‐Blind Controlled Clinical Trial
    Mohammadi, Salman, Rastmanesh, Reza, Jahangir, Farzaneh, Amiri, Zohreh, Djafarian, Kurosh, Mohsenpour, Mohammad Ali, Hassanipour, Soheil, Ghaffarian-Bahraman, Ali · 2021 · BioMed Research International
53. The Impact of Early Human Migration on Brown Adipose Tissue Evolution and Its Relevance to the Modern Obesity Pandemic
    Sellayah, Dyan · 2019 · Journal of the Endocrine Society
54. Targeting skeletal muscle mitochondrial health in obesity
    Pileggi, Chantal A., Hooks, Breana G., McPherson, Ruth, Dent, Robert R.M., Harper, Mary-Ellen · 2022 · Clinical Science
55. The effects of melatonin daily supplementation to aged rats on the ability to withstand cold, thermoregulation and body weight
    Mendes, Caroline, Gomes, Guilherme, Belpiede, Luciana Tocci, do Carmo Buonfiglio, Daniella, Motta-Teixeira, Lívia Clemente, Amaral, Fernanda Gaspar, Cipolla-Neto, José · 2021 · Life Sciences
56. Aldosterone deficiency in mice burdens respiration and accentuates diet-induced hyperinsulinemia and obesity
    Liao, Wan-Hui, Suendermann, Claudia, Steuer, Andrea Eva, Pacheco Lopez, Gustavo, Odermatt, Alex, Faresse, Nourdine, Henneberg, Maciej, Langhans, Wolfgang · 2018 · JCI Insight
57. EID1-induces brown-like adipocyte traits in white 3T3-L1 pre-adipocytes
    Lizcano, Fernando, Vargas, Diana · 2010 · Biochemical and Biophysical Research Communications
58. Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia
    Yamanishi, Kyosuke, Maeda, Seishi, Kuwahara-Otani, Sachi, Hashimoto, Takuya, Ikubo, Kaoru, Mukai, Keiichiro, Nakasho, Keiji, Gamachi, Naomi, El-Darawish, Yosif, Li, Wen et al. · 2018 · Journal of Translational Medicine
59. Post-exercise changes in myostatin and actRIIB expression in obese insulin-resistant rats
    Bueno, P.G., Bassi, D., Contrera, D.G., Carnielli, H.M., Silva, R.N., Nonaka, K.O., Selistre-de-Araújo, H.S., Leal, A.M.O. · 2011 · Molecular and Cellular Endocrinology
60. Oral Ang-(1-7) treatment improves white adipose tissue remodeling and hypertension in rats with metabolic syndrome
    Barbosa, Maria Andréa, de Sousa, Graziele Galdino, de Castro, Uberdan Guilherme Mendes, Carneiro, Cláudia Martins, Figueiredo, Vivian Paulino, Guerra de Sá, Renata, Santos, Robson Augusto Souza dos, Alzamora, Andréia Carvalho · 2019 · Nutrition
61. Effect of acute mid-intensity treadmill exercise on the androgen hormone level and uncoupling protein-1 expression in brown fat tissue of mouse
    Kim, Nahyun, Kim, Jisu, Yoo, Choongsung, Lim, Kiwon, Akimoto, Takayuki, Park, Jonghoon · 2018 · Journal of Exercise Nutrition & Biochemistry