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Executive Control Function: A Review of Its Promise and Challenges for Clinical Research. A Report From the Committee on Research of the American Neuropsychiatric Association

Royall, Donald R., Lauterbach, Edward C., Cummings, Jeffrey L., Reeve, Allison, Rummans, Teresa A., Kaufer, Daniel I., LaFrance, Jr., W. Curt, Coffey, C. Edward·2002·The Journal of Neuropsychiatry and Clinical Neurosciences
DOI 10.1176/jnp.14.4.377
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Abstract

This report reviews the state of the literature and opportunities for research related to “executive control function” (ECF). ECF has recently been separated from the specific cognitive domains (memory, language, and praxis) traditionally used to assess patients. ECF impairment has been associated with lesions to the frontal cortex and its basal ganglia–thalamic connections. No single putative ECF measure can yet serve as a “gold standard.” This and other obstacles to assessment of ECF are reviewed. ECF impairment and related frontal system lesions and metabolic disturbances have been detected in many psychiatric and medical disorders and are strongly associated with functional outcomes, disability, and specific problem behaviors. The prevalence and severity of ECF deficits in many disorders remain to be determined, and treatment has been attempted in only a few disorders. Much more research in these areas is necessary.

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Metadata

Authors
Royall, D. R., Lauterbach, E. C., Cummings, J. L., Reeve, A., Rummans, T. A., Kaufer, D. I., LaFrance, Jr., & Coffey, C. E.
Venue
The Journal of Neuropsychiatry and Clinical Neurosciences
Publisher
American Psychiatric Association Publishing
Published
2002-11
Volume
14
Issue
4
Pages
377-405
ISSN
  • 0895-0172 (ISSN-L)
  • 1545-7222
DOI
10.1176/jnp.14.4.377
OpenAlex
W2620659939
Cited by
637
References
35
FWCI
9.20
Type
journal article
Language
en
Open access
closed

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