New Perspectives on the Use of Phytochemicals as an Emergent Strategy to Control Bacterial Infections Including Biofilms

The biofilm matrix

Flemming, H.-C., & Wingender, J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2415 · Cited by 10,137

Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms

Donlan, R. M., & Costerton, J. W. (2002) · Clinical Microbiology Reviews · doi:10.1128/cmr.15.2.167-193.2002 · Cited by 6,644

Origins and evolution of antibiotic resistance

Davies, J., & Davies, D. (2010) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00016-10 · Cited by 5,784

Antibiotic resistance of bacteria in biofilms

Stewart, P. S., & William Costerton, J. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05321-1 · Cited by 4,585

Biofilms: Microbial Life on Surfaces

Donlan, R. M. (2002) · Emerging Infectious Diseases · doi:10.3201/eid0809.020063 · Cited by 4,145

Molecular mechanisms of antibiotic resistance

Blair, J. M. A., Webber, M. A., Baylay, A. J., Ogbolu, D. O., & Piddock, L. J. V. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3380 · Cited by 4,092

Plant pathogens and integrated defence responses to infection

Dangl, J. L., & Jones, J. D. G. (2001) · Nature · doi:10.1038/35081161 · Cited by 3,949

Mechanisms of biofilm resistance to antimicrobial agents

Mah, T.-F. C., & O'Toole, G. A. (2001) · Trends in Microbiology · doi:10.1016/s0966-842x(00)01913-2 · Cited by 3,921

Extended-Spectrum β-Lactamases: a Clinical Update

Paterson, D. L., & Bonomo, R. A. (2005) · Clinical Microbiology Reviews · doi:10.1128/cmr.18.4.657-686.2005 · Cited by 3,491

The Involvement of Cell-to-Cell Signals in the Development of a Bacterial Biofilm

Davies, D. G., Parsek, M. R., Pearson, J. P., Iglewski, B. H., Costerton, J. W., & Greenberg, E. P. (1998) · Science · doi:10.1126/science.280.5361.295 · Cited by 3,396

Antibiotic resistance of bacterial biofilms

Høiby, N., Bjarnsholt, T., Givskov, M., Molin, S., & Ciofu, O. (2010) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2009.12.011 · Cited by 3,225

Natural products: A continuing source of novel drug leads

Cragg, G. M., & Newman, D. J. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.02.008 · Cited by 2,906

Understanding the mechanisms and drivers of antimicrobial resistance

Holmes, A. H., Moore, L. S. P., Sundsfjord, A., Steinbakk, M., Regmi, S., Karkey, A., Guerin, P. J., & Piddock, L. J. V. (2016) · The Lancet · doi:10.1016/s0140-6736(15)00473-0 · Cited by 2,611

Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis

O'Toole, G. A., & Kolter, R. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00797.x · Cited by 2,537

A functional classification scheme for beta-lactamases and its correlation with molecular structure

Bush, K., Jacoby, G. A., & Medeiros, A. A. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.6.1211 · Cited by 2,475

Updated Functional Classification of β-Lactamases

Bush, K., & Jacoby, G. A. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01009-09 · Cited by 2,367

Call of the wild: antibiotic resistance genes in natural environments

Allen, H. K., Donato, J., Wang, H. H., Cloud-Hansen, K. A., Davies, J., & Handelsman, J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2312 · Cited by 2,361

Mechanisms of plant defense against insect herbivores

War, A. R., Paulraj, M. G., Ahmad, T., Buhroo, A. A., Hussain, B., Ignacimuthu, S., & Sharma, H. C. (2012) · Plant Signaling & Behavior · doi:10.4161/psb.21663 · Cited by 2,180

Abiotic and biotic stress combinations

Suzuki, N., Rivero, R. M., Shulaev, V., Blumwald, E., & Mittler, R. (2014) · New Phytologist · doi:10.1111/nph.12797 · Cited by 2,153

Riddle of Biofilm Resistance

Lewis, K. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.4.999-1007.2001 · Cited by 1,980

beta-Lactamases in laboratory and clinical resistance

Livermore, D. M. (1995) · Clinical Microbiology Reviews · doi:10.1128/cmr.8.4.557 · Cited by 1,779

Outer membrane permeability and antibiotic resistance

Delcour, A. H. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2008.11.005 · Cited by 1,762

Three Decades of β-Lactamase Inhibitors

Drawz, S. M., & Bonomo, R. A. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00037-09 · Cited by 1,709

The shared antibiotic resistome of soil bacteria and human pathogens

Forsberg, K. J., Reyes, A., Wang, B., Selleck, E. M., Sommer, M. O. A., & Dantas, G. (2012) · Science · doi:10.1126/science.1220761 · Cited by 1,650

Molecular Mechanisms of Antibacterial Multidrug Resistance

Alekshun, M. N., & Levy, S. B. (2007) · Cell · doi:10.1016/j.cell.2007.03.004 · Cited by 1,647

Sampling the Antibiotic Resistome

D'Costa, V. M., McGrann, K. M., Hughes, D. W., & Wright, G. D. (2006) · Science · doi:10.1126/science.1120800 · Cited by 1,594

Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms

Singh, P. K., Schaefer, A. L., Parsek, M. R., Moninger, T. O., Welsh, M. J., & Greenberg, E. P. (2000) · Nature · doi:10.1038/35037627 · Cited by 1,519

Bacterial adhesion: seen any good biofilms lately

Dunne, W. M. (2002) · Clinical Microbiology Reviews · doi:10.1128/cmr.15.2.155-166.2002 · Cited by 1,516

Growing Group of Extended-Spectrum β-Lactamases: the CTX-M Enzymes

Bonnet, R. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.1.1-14.2004 · Cited by 1,494

Platforms for antibiotic discovery

Lewis, K. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd3975 · Cited by 1,445

Mechanisms of antibiotic resistance in bacterial biofilms

Stewart, P. S. (2002) · International Journal of Medical Microbiology · doi:10.1078/1438-4221-00196 · Cited by 1,385

Anti-virulence strategies to combat bacteria-mediated disease

Rasko, D. A., & Sperandio, V. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3013 · Cited by 1,373

Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics

Lebeaux, D., Ghigo, J.-M., & Beloin, C. (2014) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00013-14 · Cited by 1,318

Synergy research: approaching a new generation of phytopharmaceuticals.

Wagner, H., & Ulrich-Merzenich, G. (2009) · Phytomedicine · doi:10.1016/j.phymed.2008.12.018 · Cited by 1,296

Clinically Relevant Chromosomally Encoded Multidrug Resistance Efflux Pumps in Bacteria

Piddock, L. J. V. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.19.2.382-402.2006 · Cited by 1,231

Antimicrobial properties of allicin from garlic

Ankri, S., & Mirelman, D. (1999) · Microbes and Infection · doi:10.1016/s1286-4579(99)80003-3 · Cited by 1,177

Thoughts and facts about antibiotics: Where we are now and where we are heading

Bérdy, J. (2012) · The Journal of Antibiotics · doi:10.1038/ja.2012.27 · Cited by 1,165

Persister cells and tolerance to antimicrobials

Keren, I., Kaldalu, N., Spoering, A., Wang, Y., & Lewis, K. (2004) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(03)00856-5 · Cited by 1,098

A component of innate immunity prevents bacterial biofilm development

Singh, P. K., Parsek, M. R., Greenberg, E. P., & Welsh, M. J. (2002) · Nature · doi:10.1038/417552a · Cited by 1,026

Quorum sensing inhibitors: An overview

Kalia, V. C. (2013) · Biotechnology Advances · doi:10.1016/j.biotechadv.2012.10.004 · Cited by 971

Origins and evolution of antibiotic resistance.

DAVIES, J. E. (1996) · PubMed · Cited by 941

Plant Defense against Insect Herbivores

Fürstenberg-Hägg, J., Zagrobelny, M., & Bak, S. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140510242 · Cited by 929

Strategies for combating bacterial biofilm infections

Wu, H., Moser, C., Wang, H.-Z., Høiby, N., & Song, Z.-J. (2015) · International Journal of Oral Science · doi:10.1038/ijos.2014.65 · Cited by 925

Synergism between natural products and antibiotics against infectious diseases

Hemaiswarya, S., Kruthiventi, A. K., & Doble, M. (2008) · Phytomedicine · doi:10.1016/j.phymed.2008.06.008 · Cited by 916

Adaptive and Mutational Resistance: Role of Porins and Efflux Pumps in Drug Resistance

Fernández, L., & Hancock, R. E. W. (2012) · Clinical Microbiology Reviews · doi:10.1128/cmr.00043-12 · Cited by 892

Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance

Woodford, N., Turton, J. F., & Livermore, D. M. (2011) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2011.00268.x · Cited by 885

The importance of efflux pumps in bacterial antibiotic resistance

Webber, M. A. (2003) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkg050 · Cited by 853

Antibiotic resistance in the environment: a link to the clinic?

Wright, G. D. (2010) · Current Opinion in Microbiology · doi:10.1016/j.mib.2010.08.005 · Cited by 831

The emergence and evolution of methicillin-resistant Staphylococcus aureus

Hiramatsu, K., Cui, L., Kuroda, M., & Ito, T. (2001) · Trends in Microbiology · doi:10.1016/s0966-842x(01)02175-8 · Cited by 825

Exploiting Quorum Sensing To Confuse Bacterial Pathogens

LaSarre, B., & Federle, M. J. (2013) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00046-12 · Cited by 820

Iron and Pseudomonas aeruginosa biofilm formation

Banin, E., Vasil, M. L., & Greenberg, E. P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504266102 · Cited by 801

Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies

de la Fuente-Núñez, C., Reffuveille, F., Fernández, L., & Hancock, R. E. (2013) · Current Opinion in Microbiology · doi:10.1016/j.mib.2013.06.013 · Cited by 801

The New β-Lactamases

Jacoby, G. A., & Munoz-Price, L. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmra041359 · Cited by 787

Bacterial multidrug efflux pumps: Mechanisms, physiology and pharmacological exploitations

Sun, J., Deng, Z., & Yan, A. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.05.090 · Cited by 746

Quorum-sensing inhibitors as anti-pathogenic drugs

Rasmussen, T. B., & Givskov, M. (2006) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2006.02.005 · Cited by 737

The role of aquatic ecosystems as reservoirs of antibiotic resistance

Marti, E., Variatza, E., & Balcazar, J. L. (2014) · Trends in Microbiology · doi:10.1016/j.tim.2013.11.001 · Cited by 724

Two Classes of Plant Antibiotics: Phytoalexins versus "Phytoanticipins"

VanEtten, H. D., Mansfield, J. W., Bailey, J. A., & Farmer, E. E. (1994) · The Plant Cell · doi:10.1105/tpc.6.9.1191 · Cited by 710

Gene transfer occurs with enhanced efficiency in biofilms and induces enhanced stabilisation of the biofilm structure

Molin, S., & Tolker-Nielsen, T. (2003) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(03)00036-3 · Cited by 708

Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon

Poole, K., Krebes, K., McNally, C., & Neshat, S. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.22.7363-7372.1993 · Cited by 688

Biofilm formation and the food industry, a focus on the bacterial outer surface: Biofilm formation and the bacterial outer surface

Van Houdt, R., & Michiels, C. W. (2010) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2010.04756.x · Cited by 684

The emerging NDM carbapenemases

Nordmann, P., Poirel, L., Walsh, T. R., & Livermore, D. M. (2011) · Trends in Microbiology · doi:10.1016/j.tim.2011.09.005 · Cited by 663

Bacteria Subsisting on Antibiotics

Dantas, G., Sommer, M. O. A., Oluwasegun, R. D., & Church, G. M. (2008) · Science · doi:10.1126/science.1155157 · Cited by 654

Plant-Derived Antimicrobial Compounds: Alternatives to Antibiotics

Savoia, D. (2012) · Future Microbiology · doi:10.2217/fmb.12.68 · Cited by 601

Novel classes of antibiotics or more of the same?

Coates, A. R., Halls, G., & Hu, Y. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01250.x · Cited by 598

Quorum Sensing Inhibitors Increase the Susceptibility of Bacterial Biofilms to Antibiotics In Vitro and In Vivo

Brackman, G., Cos, P., Maes, L., Nelis, H. J., & Coenye, T. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00045-11 · Cited by 561

Bacterial efflux pump inhibitors from natural sources

Stavri, M., Piddock, L. J. V., & Gibbons, S. (2007) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkl460 · Cited by 547

Uncultured soil bacteria are a reservoir of new antibiotic resistance genes

Riesenfeld, C. S., Goodman, R. M., & Handelsman, J. (2004) · Environmental Microbiology · doi:10.1111/j.1462-2920.2004.00664.x · Cited by 527

Persister cells and the riddle of biofilm survival

Lewis, K. (2005) · Biochemistry (Moscow) · doi:10.1007/s10541-005-0111-6 · Cited by 520

Plants as sources of new antimicrobials and resistance-modifying agents

Abreu, A. C., McBain, A. J., & Simões, M. (2012) · Natural Product Reports · doi:10.1039/c2np20035j · Cited by 519

Multidrug Pump Inhibitors Uncover Remarkable Activity of Plant Antimicrobials

Tegos, G., Stermitz, F. R., Lomovskaya, O., & Lewis, K. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.10.3133-3141.2002 · Cited by 517

Applying insights from biofilm biology to drug development — can a new approach be developed?

Bjarnsholt, T., Ciofu, O., Molin, S., Givskov, M., & Høiby, N. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd4000 · Cited by 516

Interactions among Strategies Associated with Bacterial Infection: Pathogenicity, Epidemicity, and Antibiotic Resistance

Martínez, J. L., & Baquero, F. (2002) · Clinical Microbiology Reviews · doi:10.1128/cmr.15.4.647-679.2002 · Cited by 514

Role of efflux pumps in the antibiotic resistance of bacteria embedded in a biofilm

Soto, S. M. (2013) · Virulence · doi:10.4161/viru.23724 · Cited by 513

The β-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter

Livermore, D. M., & Woodford, N. (2006) · Trends in Microbiology · doi:10.1016/j.tim.2006.07.008 · Cited by 510

Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

Bjarnsholt, T., Jensen, P. Ø., Burmølle, M., Hentzer, M., Haagensen, J. A. J., Hougen, H. P., Calum, H., Madsen, K. G., Moser, C., Molin, S., et al. (2005) · Microbiology · doi:10.1099/mic.0.27463-0 · Cited by 500

Mechanisms of antibiotic resistance in Pseudomonas aeruginosa.

Lambert, P. A. (2002) · Europe PMC (PubMed Central) · Cited by 489

Chelator-Induced Dispersal and Killing of Pseudomonas aeruginosa Cells in a Biofilm

Banin, E., Brady, K. M., & Greenberg, E. P. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.3.2064-2069.2006 · Cited by 473

A Dose-Response Study of Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

Brooun, A., Liu, S., & Lewis, K. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.3.640-646.2000 · Cited by 473

Prevention and control of biofilm-based medical-device-related infections

Francolini, I., & Donelli, G. (2010) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2010.00665.x · Cited by 470

Co-evolution and plant resistance to natural enemies

Rausher, M. D. (2001) · Nature · doi:10.1038/35081193 · Cited by 458

Ajoene, a Sulfur-Rich Molecule from Garlic, Inhibits Genes Controlled by Quorum Sensing

Jakobsen, T. H., van Gennip, M., Phipps, R. K., Shanmugham, M. S., Christensen, L. D., Alhede, M., Skindersoe, M. E., Rasmussen, T. B., Friedrich, K., Uthe, F., et al. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05919-11 · Cited by 458

Understanding antimicrobial activities of phytochemicals against multidrug resistant bacteria and biofilms

Simões, M., Bennett, R. N., & Rosa, E. A. S. (2009) · Natural Product Reports · doi:10.1039/b821648g · Cited by 444

Molecular mechanisms of antibiotic resistance

Wright, G. D. (2011) · Chemical Communications · doi:10.1039/c0cc05111j · Cited by 443

Biofilms and antibiotic therapy: Is there a role for combating bacterial resistance by the use of novel drug delivery systems?

SMITH, A. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.04.007 · Cited by 443

Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

Bjarnsholt, T., Jensen, P. Ø., Rasmussen, T. B., Christophersen, L., Calum, H., Hentzer, M., Hougen, H.-P., Rygaard, J., Moser, C., Eberl, L., et al. (2005) · Microbiology · doi:10.1099/mic.0.27955-0 · Cited by 440

Essential Oils, A New Horizon in Combating Bacterial Antibiotic Resistance

Yap, P. S. X., Yiap, B. C., Ping, H. C., & Lim, S. H. E. (2014) · The Open Microbiology Journal · doi:10.2174/1874285801408010006 · Cited by 426

Inhibition of biofilm development of uropathogens by curcumin – An anti-quorum sensing agent from Curcuma longa

Packiavathy, I. A. S. V., Priya, S., Pandian, S. K., & Ravi, A. V. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2012.08.002 · Cited by 413

Plant Antimicrobial Agents and Their Effects on Plant and Human Pathogens

González-Lamothe, R., Mitchell, G., Gattuso, M., Diarra, M. S., Malouin, F., & Bouarab, K. (2009) · International Journal of Molecular Sciences · doi:10.3390/ijms10083400 · Cited by 413

Global spread of antibiotic resistance: the example of New Delhi metallo-β-lactamase (NDM)-mediated carbapenem resistance

Johnson, A. P., & Woodford, N. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.052555-0 · Cited by 411

Biofilms and Antimicrobial Resistance

Patel, R. (2005) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000175714.68624.74 · Cited by 390

Involvement of a Novel Efflux System in Biofilm-Specific Resistance to Antibiotics

Zhang, L., & Mah, T.-F. (2008) · Journal of Bacteriology · doi:10.1128/jb.01655-07 · Cited by 385

Dietary phytochemicals as quorum sensing inhibitors

Vattem, D. A., Mihalik, K., Crixell, S. H., & McLean, R. J. C. (2007) · Fitoterapia · doi:10.1016/j.fitote.2007.03.009 · Cited by 378

Iron, copper, zinc, and manganese transport and regulation in pathogenic Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence

Porcheron, G., Garénaux, A., Proulx, J., Sabri, M., & Dozois, C. M. (2013) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2013.00090 · Cited by 366

Antibiotic Resistance Mechanisms of Clinically Important Bacteria

Giedraitienė, A., Vitkauskienė, A., Naginienė, R., & Pavilonis, A. (2011) · Medicina · doi:10.3390/medicina47030019 · Cited by 362

Synergism between plant extract and antimicrobial drugs used on Staphylococcus aureus diseases

Betoni, J. E. C., Mantovani, R. P., Barbosa, L. N., Di Stasi, L. C., & Fernandes Junior, A. (2006) · Memórias do Instituto Oswaldo Cruz · doi:10.1590/s0074-02762006000400007 · Cited by 359

Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms

Suci, P. A., Mittelman, M. W., Yu, F. P., & Geesey, G. G. (1994) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.38.9.2125 · Cited by 357

Inactivation of Efflux Pumps Abolishes Bacterial Biofilm Formation

Kvist, M., Hancock, V., & Klemm, P. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.01310-08 · Cited by 353

Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens

Sybiya Vasantha Packiavathy, I. A., Agilandeswari, P., Musthafa, K. S., Karutha Pandian, S., & Veera Ravi, A. (2012) · Food Research International · doi:10.1016/j.foodres.2011.10.022 · Cited by 350

Bacterial Quorum Sensing: Signals, Circuits, and Implications for Biofilms and Disease

Jayaraman, A., & Wood, T. K. (2008) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.10.061807.160536 · Cited by 348

Effects of iron on DNA release and biofilm development by Pseudomonas aeruginosa

Yang, L., Barken, K. B., Skindersoe, M. E., Christensen, A. B., Givskov, M., & Tolker-Nielsen, T. (2007) · Microbiology · doi:10.1099/mic.0.2006/004911-0 · Cited by 347

Environmental dissemination of antibiotic resistance genes and correlation to anthropogenic contamination with antibiotics

Berglund, B. (2015) · Infection Ecology & Epidemiology · doi:10.3402/iee.v5.28564 · Cited by 333

Mechanisms of drug efflux and strategies to combat them: Challenging the efflux pump of Gram-negative bacteria

Pagès, J.-M., & Amaral, L. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2008.12.011 · Cited by 329

Identification of Catechin as One of the Flavonoids from Combretum albiflorum Bark Extract That Reduces the Production of Quorum-Sensing-Controlled Virulence Factors in Pseudomonas aeruginosa PAO1

Vandeputte, O. M., Kiendrebeogo, M., Rajaonson, S., Diallo, B., Mol, A., El Jaziri, M., & Baucher, M. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.01059-09 · Cited by 326

Antibiotic Adjuvants: Diverse Strategies for Controlling Drug‐Resistant Pathogens

Gill, E. E., Franco, O. L., & Hancock, R. E. W. (2015) · Chemical Biology & Drug Design · doi:10.1111/cbdd.12478 · Cited by 319

6-Gingerol reduces Pseudomonas aeruginosa biofilm formation and virulence via quorum sensing inhibition

Kim, H.-S., Lee, S.-H., Byun, Y., & Park, H.-D. (2015) · Scientific Reports · doi:10.1038/srep08656 · Cited by 317

Antibiotic resistance in Pseudomonas aeruginosa and alternative therapeutic options

Chatterjee, M., Anju, C. P., Biswas, L., Anil Kumar, V., Gopi Mohan, C., & Biswas, R. (2016) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2015.11.004 · Cited by 312

Chemical Diversity and Defence Metabolism: How Plants Cope with Pathogens and Ozone Pollution

Iriti, M., & Faoro, F. (2009) · International Journal of Molecular Sciences · doi:10.3390/ijms10083371 · Cited by 294

Update of the Standard Numbering Scheme for Class B β-Lactamases

Garau, G., García-Sáez, I., Bebrone, C., Anne, C., Mercuri, P., Galleni, M., Frère, J.-M., & Dideberg, O. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.7.2347-2349.2004 · Cited by 286

Geraniol Restores Antibiotic Activities against Multidrug-Resistant Isolates from Gram-Negative Species

Lorenzi, V., Muselli, A., Bernardini, A. F., Berti, L., Pagès, J.-M., Amaral, L., & Bolla, J.-M. (2009) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00919-08 · Cited by 278

Bacterial efflux systems and efflux pumps inhibitors

Marquez, B. (2005) · Biochimie · doi:10.1016/j.biochi.2005.04.012 · Cited by 270

The Natural Antimicrobial Carvacrol Inhibits Quorum Sensing in Chromobacterium violaceum and Reduces Bacterial Biofilm Formation at Sub-Lethal Concentrations

Burt, S. A., Ojo-Fakunle, V. T. A., Woertman, J., & Veldhuizen, E. J. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093414 · Cited by 263

In vitro analysis of iron chelating activity of flavonoids

Mladěnka, P., Macáková, K., Filipský, T., Zatloukalová, L., Jahodář, L., Bovicelli, P., Silvestri, I. P., Hrdina, R., & Saso, L. (2011) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2011.02.003 · Cited by 255

Strategies for bypassing the membrane barrier in multidrug resistant Gram‐negative bacteria

Bolla, J.-M., Alibert-Franco, S., Handzlik, J., Chevalier, J., Mahamoud, A., Boyer, G., Kieć-Kononowicz, K., & Pagès, J.-M. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.04.054 · Cited by 250

Antibiotic adjuvants: multicomponent anti-infective strategies

Kalan, L., & Wright, G. D. (2011) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399410001766 · Cited by 249

In vitro efficacy of bioactive extracts of 15 medicinal plants against ESβL-producing multidrug-resistant enteric bacteria

Ahmad, I., & Aqil, F. (2007) · Microbiological Research · doi:10.1016/j.micres.2006.06.010 · Cited by 244

Influence of calcium ions on the mechanical properties of a model biofilm of mucoid Pseudomonas aeruginosa

Körstgens, V., Flemming, H., Wingender, J., & Borchard, W. (2001) · Water Science & Technology · doi:10.2166/wst.2001.0338 · Cited by 243

Synthetic and natural iron chelators: Therapeutic potential and clinical use

Hatcher, H. C., Singh, R. N., Torti, F. M., & Torti, S. V. (2009) · Future Medicinal Chemistry · doi:10.4155/fmc.09.121 · Cited by 242

Activity and interactions of antibiotic and phytochemical combinations against Pseudomonas aeruginosa in vitro

Jayaraman, P., Sakharkar, M. K., Lim, C. S., Tang, T. H., & Sakharkar, K. R. (2010) · International Journal of Biological Sciences · doi:10.7150/ijbs.6.556 · Cited by 241

Inhibitors of efflux pumps in Gram-negative bacteria

Pagès, J., Masi, M., & Barbe, J. (2005) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2005.06.006 · Cited by 239

Environmental Deterioration and Human Health: Natural and anthropogenic determinants

Malik, A., Grohmann, E., & Akhtar, R. (2013) · Springer eBooks · doi:10.1007/978-94-007-7890-0 · Cited by 237

Increased mutability of Pseudomonas aeruginosa in biofilms

Driffield, K., Miller, K., Bostock, J. M., O'Neill, A. J., & Chopra, I. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn044 · Cited by 234

Defining an extended-spectrum β-lactamase

Livermore, D. M. (2008) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2007.01857.x · Cited by 232

Susceptibility of Pseudomonas aeruginosa and Escherichia coli biofilms towards ciprofloxacin: effect of specific growth rate

Evans, D. J., Allison, D., Brown, M. R., & Gilbert, P. (1991) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/27.2.177 · Cited by 230

Role of quorum sensing in bacterial infections

Castillo‐Juárez, I., Maeda, T., Mandujano-Tinoco, E. A., Tomás, M., Peréz-Eretza, B., García-Contreras, S. J., Wood, T. K., & García‐Contreras, R. (2015) · World Journal of Clinical Cases · doi:10.12998/wjcc.v3.i7.575 · Cited by 225

The origins and molecular basis of antibiotic resistance

Hawkey, P. M. (1998) · BMJ · doi:10.1136/bmj.317.7159.657 · Cited by 222

Innovative Strategies to Overcome Biofilm Resistance

Taraszkiewicz, A., Fila, G., Grinholc, M., & Nakonieczna, J. (2013) · BioMed Research International · doi:10.1155/2013/150653 · Cited by 216

Eugenol inhibits quorum sensing at sub-inhibitory concentrations

Zhou, L., Zheng, H., Tang, Y., Yu, W., & Gong, Q. (2013) · Biotechnology Letters · doi:10.1007/s10529-012-1126-x · Cited by 212

Food as a Source for Quorum Sensing Inhibitors: Iberin from Horseradish Revealed as a Quorum Sensing Inhibitor of Pseudomonas aeruginosa

Jakobsen, T. H., Bragason, S. K., Phipps, R. K., Hultqvist, L. D., van Gennip, M., Alhede, M., Skindersoe, M. E., Larsen, T. O., Høiby, N., Bjarnsholt, T., et al. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.05992-11 · Cited by 212

The threat of antibiotic resistance in Gram-negative pathogenic bacteria: β-lactams in peril!

Thomson, J. M., & Bonomo, R. A. (2005) · Current Opinion in Microbiology · doi:10.1016/j.mib.2005.08.014 · Cited by 212

Iron Salts Perturb Biofilm Formation and Disrupt Existing Biofilms of Pseudomonas aeruginosa

Musk, D. J., Banko, D. A., & Hergenrother, P. J. (2005) · Chemistry & Biology · doi:10.1016/j.chembiol.2005.05.007 · Cited by 210

Ellagic Acid Derivatives from Terminalia chebula Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate Pseudomonas aeruginosa PAO1 Virulence

Sarabhai, S., Sharma, P., & Capalash, N. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053441 · Cited by 207

Inhibitory effect of zingiber officinale towards Streptococcus mutans virulence and caries development: in vitro and in vivo studies

Hasan, S., Danishuddin, M., & Khan, A. U. (2015) · BMC Microbiology · doi:10.1186/s12866-014-0320-5 · Cited by 200

Antibiotic Resistance Mechanisms in Bacteria: Biochemical and Genetic Aspects

Kos, B., Džidić, S., & Šušković, J. (2008) · University of Zagreb University Computing Centre (SRCE) · Cited by 199

Influence of Quorum Sensing and Iron on Twitching Motility and Biofilm Formation in Pseudomonas aeruginosa

Patriquin, G. M., Banin, E., Gilmour, C., Tuchman, R., Greenberg, E. P., & Poole, K. (2007) · Journal of Bacteriology · doi:10.1128/jb.01473-07 · Cited by 197

Evolution of Resistance to Quorum-Sensing Inhibitors

Kalia, V. C., Wood, T. K., & Kumar, P. (2013) · Microbial Ecology · doi:10.1007/s00248-013-0316-y · Cited by 196

Antiquorum Sensing and Antibiofilm Potential of Capparis spinosa

Packiavathy, I. A. S. V., Agilandeswari, P., Ramaswamy, B. R., Pandian, S. K., & Arumugam, V. R. (2011) · Archives of Medical Research · doi:10.1016/j.arcmed.2011.12.002 · Cited by 195

LmrS Is a Multidrug Efflux Pump of the Major Facilitator Superfamily from Staphylococcus aureus

Floyd, J. L., Smith, K. P., Kumar, S. H., Floyd, J. T., & Varela, M. F. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00580-10 · Cited by 194

Antimicrobial and Efflux Pump Inhibitory Activity of Caffeoylquinic Acids from Artemisia absinthium against Gram-Positive Pathogenic Bacteria

Fiamegos, Y. C., Kastritis, P. L., Exarchou, V., Han, H., Bonvin, A. M. J. J., Vervoort, J., Lewis, K., Hamblin, M. R., & Tegos, G. P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018127 · Cited by 190

The challenges of overcoming antibiotic resistance: Plant extracts as potential sources of antimicrobial and resistance modifying agents

Sibanda, T., & Okoh, A. I. (2007) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb2007.000-2458 · Cited by 190

Control of plant diseases by natural products: Allicin from garlic as a case study

Slusarenko, A. J., Patel, A., & Portz, D. (2008) · European Journal of Plant Pathology · doi:10.1007/s10658-007-9232-7 · Cited by 189

Clinical impact and relevance of antibiotic resistance

French, G. L. (2005) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.04.005 · Cited by 189

Loss of or inhibition of all multidrug resistance efflux pumps of Salmonella enterica serovar Typhimurium results in impaired ability to form a biofilm

Baugh, S. D. P., Ekanayaka, A. S., Piddock, L. J. V., & Webber, M. A. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks228 · Cited by 189

Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens

Bjarnsholt, T., & Givskov, M. (2007) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2007.2046 · Cited by 187

Polyphenolic extract from Rosa rugosa tea inhibits bacterial quorum sensing and biofilm formation

Zhang, J., Rui, X., Wang, L., Guan, Y., Sun, X., & Dong, M. (2014) · Food Control · doi:10.1016/j.foodcont.2014.02.001 · Cited by 180

Siderophore–drug complexes: potential medicinal applications of the ‘Trojan horse’ strategy

Górska, A., Sloderbach, A., & Marszałł, M. P. (2014) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2014.06.007 · Cited by 177

Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model

Christensen, L. D., van Gennip, M., Jakobsen, T. H., Alhede, M., Hougen, H. P., Hoiby, N., Bjarnsholt, T., & Givskov, M. (2012) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks002 · Cited by 177

Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target

Chang, C., Krishnan, T., Wang, H., Chen, Y., Yin, W., Chong, Y. M., Tan, L. Y., Chong, T. M., & Chan, K. (2014) · Scientific Reports · doi:10.1038/srep07245 · Cited by 176

Antibiotic-resistant soil bacteria in transgenic plant fields

Demanèche, S., Sanguin, H., Poté, J., Navarro, E., Bernillon, D., Mavingui, P., Wildi, W., Vogel, T. M., & Simonet, P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800072105 · Cited by 174

The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

Brackman, G., Breyne, K., De Rycke, R., Vermote, A., Van Nieuwerburgh, F., Meyer, E., Van Calenbergh, S., & Coenye, T. (2016) · Scientific Reports · doi:10.1038/srep20321 · Cited by 174

Inhibitors of Multidrug Resistant Efflux Systems in Bacteria

Zechini, B., & Versace, I. (2009) · Recent Patents on Anti-Infective Drug Discovery · doi:10.2174/157489109787236256 · Cited by 172

Screening of traditional Chinese medicinal plants for quorum-sensing inhibitors activity

Koh, K. H., & Tham, F.-Y. (2011) · Journal of Microbiology, Immunology and Infection · doi:10.1016/j.jmii.2009.10.001 · Cited by 172

Evaluation of Anti-Quorum-Sensing Activity of Edible Plants and Fruits through Inhibition of the N-Acyl-Homoserine Lactone System in Chromobacterium violaceum and Pseudomonas aeruginosa

Musthafa, K. S., Ravi, A. V., Annapoorani, A., Packiavathy, I. S. V., & Pandian, S. K. (2010) · Chemotherapy · doi:10.1159/000320185 · Cited by 170

Contribution of Stress Responses to Antibiotic Tolerance in Pseudomonas aeruginosa Biofilms

Stewart, P. S., Franklin, M. J., Williamson, K. S., Folsom, J. P., Boegli, L., & James, G. A. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00433-15 · Cited by 167

In Vitro and Ex Vivo Activities of Minocycline and EDTA against Microorganisms Embedded in Biofilm on Catheter Surfaces

RAAD, I. I., Chatzinikolaou, I., Chaiban, G., Hanna, H. A., Hachem, R. Y., Dvorak, T. L., Cook, G. S., & Costerton, W. J. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.11.3580-3585.2003 · Cited by 166

Sub-MICs of Mentha piperita essential oil and menthol inhibits AHL mediated quorum sensing and biofilm of Gram-negative bacteria

Husain, F. M., Ahmad, I., Khan, M. S., Ahmad, E., Tahseen, Q., Khan, M. S., & Alshabib, N. A. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00420 · Cited by 163

Small Molecule Disruption of Quorum Sensing Cross-Regulation in Pseudomonas aeruginosa Causes Major and Unexpected Alterations to Virulence Phenotypes

Welsh, M. A., Eibergen, N. R., Moore, J. D., & Blackwell, H. E. (2015) · Journal of the American Chemical Society · doi:10.1021/ja5110798 · Cited by 162

Inhibition of multidrug efflux as a strategy to prevent biofilm formation

Baugh, S. D. P., Phillips, C. R., Ekanayaka, A. S., Piddock, L. J. V., & Webber, M. A. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkt420 · Cited by 162

Emerging antibiotic resistance in bacteria with special reference to India

Raghunath, D. (2008) · Journal of Biosciences · doi:10.1007/s12038-008-0077-9 · Cited by 160

Hacking into bacterial biofilms: a new therapeutic challenge

Bordi, C., & de Bentzmann, S. (2011) · Annals of Intensive Care · doi:10.1186/2110-5820-1-19 · Cited by 158

Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence

Chen, F., Di, H., Wang, Y., Cao, Q., Xu, B., Zhang, X. C., Yang, N., Liu, G., Yang, C., Xu, Y., et al. (2016) · Nature Chemical Biology · doi:10.1038/nchembio.2003 · Cited by 156

Effect of Cinnamon Oil on Quorum Sensing-Controlled Virulence Factors and Biofilm Formation in Pseudomonas aeruginosa

Kalia, M., Yadav, V. K., Singh, P. K., Sharma, D., Pandey, H., Narvi, S. S., & Agarwal, V. K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135495 · Cited by 155

Use of bioactive plant products in combination with standard antibiotics: Implications in antimicrobial chemotherapy

Aiyegoro, O. A., & Okoh, A. I. (2009) · Journal of Medicinal Plants Research · doi:10.5897/jmpr.9001277 · Cited by 155

Metagenomic Analysis of Apple Orchard Soil Reveals Antibiotic Resistance Genes Encoding Predicted Bifunctional Proteins

Donato, J. J., Moe, L. A., Converse, B. J., Smart, K. D., Berklein, F. C., McManus, P. S., & Handelsman, J. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.01763-09 · Cited by 155

Insights on Antimicrobial Resistance, Biofilms and the Use of Phytochemicals as New Antimicrobial Agents

Borges, A. D. S., Saavedra, M. J., & Simões, M. V. (2015) · Current Medicinal Chemistry · doi:10.2174/0929867322666150530210522 · Cited by 155

Calcium-chelating alizarin and other anthraquinones inhibit biofilm formation and the hemolytic activity of Staphylococcus aureus

Lee, J., Kim, Y., Ryu, S. Y., & Lee, J. (2016) · Scientific Reports · doi:10.1038/srep19267 · Cited by 153

Synthesis and quorum sensing inhibitory activity of key phenolic compounds of ginger and their derivatives

Kumar, N. V., Murthy, P. S., Manjunatha, J. R., & Bettadaiah, B. K. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2014.03.039 · Cited by 152

Influence of clove oil on certain quorum-sensing-regulated functions and biofilm of Pseudomonas aeruginosa and Aeromonas hydrophila

Husain, F. M., Ahmad, I., Asif, M., & Tahseen, Q. (2013) · Journal of Biosciences · doi:10.1007/s12038-013-9385-9 · Cited by 151

Biologically inspired strategies for combating bacterial biofilms

Blackledge, M. S., Worthington, R. J., & Melander, C. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.07.004 · Cited by 149

Involvement of Iron in Biofilm Formation by Staphylococcus aureus

Lin, M., Shu, J., Huang, H.-Y., & Cheng, Y.-C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034388 · Cited by 148

Bacterial Efflux Pumps Involved in Multidrug Resistance and their Inhibitors: Rejuvinating the Antimicrobial Chemotherapy

Bhardwaj, A. K., & Mohanty, P. (2012) · Recent Patents on Anti-Infective Drug Discovery · doi:10.2174/157489112799829710 · Cited by 148

Evaluation of the effects of selected phytochemicals on quorum sensing inhibition andin vitrocytotoxicity

Borges, A. D. S., Serra, S. C., Abreu, A. C., Saavedra, M. J., Salgado, A. J., & Simões, M. V. (2013) · Biofouling · doi:10.1080/08927014.2013.852542 · Cited by 146

Antibiotic Resistance in Bacteria Isolated from the Deep Terrestrial Subsurface

Brown, M. G., & Balkwill, D. L. (2008) · Microbial Ecology · doi:10.1007/s00248-008-9431-6 · Cited by 143

Zingerone silences quorum sensing and attenuates virulence of Pseudomonas aeruginosa

Kumar, L., Chhibber, S., Kumar, R., Kumar, M., & Harjai, K. (2015) · Fitoterapia · doi:10.1016/j.fitote.2015.02.002 · Cited by 143

Role of electrostatic interactions in cohesion of bacterial biofilms

Chen, X. D., & Stewart, P. S. (2002) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-002-1044-2 · Cited by 142

Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm

Ding, X., Yin, B., Li, Q., Zeng, Z., Yang, Z., Li, H., Lu, Y., & Zhou, S. (2011) · Journal of Medical Microbiology · doi:10.1099/jmm.0.024166-0 · Cited by 142

Prevention of quorum-sensing-mediated biofilm development and virulence factors production in Vibrio spp. by curcumin

Packiavathy, I. A. S. V., Sasikumar, P., Pandian, S. K., & Ravi, A. V. (2013) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-013-4704-5 · Cited by 142

Physiology of Pseudomonas aeruginosa in biofilms as revealed by transcriptome analysis

Folsom, J. P., Richards, L., Pitts, B., Roe, F., Ehrlich, G. D., Parker, A. E., Mazurie, A., & Stewart, P. S. (2010) · BMC Microbiology · doi:10.1186/1471-2180-10-294 · Cited by 142

Antimicrobial, antibiotic potentiating activity and phytochemical profile of essential oils from exotic and endemic medicinal plants of Mauritius

Aumeeruddy-Elalfi, Z., Gurib‐Fakim, A., & Mahomoodally, M. F. (2015) · Industrial Crops and Products · doi:10.1016/j.indcrop.2015.03.058 · Cited by 138

The Burkholderia pseudomallei BpeAB-OprB Efflux Pump: Expression and Impact on Quorum Sensing and Virulence

Chan, Y. Y., & Chua, K. L. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.14.4707-4719.2005 · Cited by 136

β-Lactam/β-Lactamase Inhibitor Combinations: From Then to Now

Toussaint, K. A., & Gallagher, J. C. (2015) · Annals of Pharmacotherapy · doi:10.1177/1060028014556652 · Cited by 136

Medicinal plant extracts with efflux inhibitory activity against Gram-negative bacteria

Garvey, M. I., Rahman, M. M., Gibbons, S., & Piddock, L. J. V. (2010) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2010.10.027 · Cited by 135

Anti-quorum sensing activity of flavonoid-rich fraction from Centella asiatica L. against Pseudomonas aeruginosa PAO1

Vasavi, H. S., Arun, A. B., & Rekha, P. D. (2014) · Journal of Microbiology Immunology and Infection · doi:10.1016/j.jmii.2014.03.012 · Cited by 131

Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux Pumps

Mahmood, H. Y., Jamshidi, S., Sutton, J. M., & Rahman, K. M. (2016) · Current Medicinal Chemistry · doi:10.2174/0929867323666160304150522 · Cited by 127

Computational discovery of putative quorum sensing inhibitors against LasR and RhlR receptor proteins of Pseudomonas aeruginosa

Annapoorani, A., Umamageswaran, V., Parameswari, R., Pandian, S. K., & Ravi, A. V. (2012) · Journal of Computer-Aided Molecular Design · doi:10.1007/s10822-012-9599-1 · Cited by 122

Iron-binding compounds impair Pseudomonas aeruginosa biofilm formation, especially under anaerobic conditions

O'May, C. Y., Sanderson, K. R., Roddam, L. F., Kirov, S. M., & Reid, D. W. (2009) · Journal of Medical Microbiology · doi:10.1099/jmm.0.004416-0 · Cited by 122

Roles of Multidrug Efflux Pumps on the Biofilm Formation of Escherichia coli K-12

MATSUMURA, K., Furukawa, S., Ogihara, H., & Morinaga, Y. (2011) · Biocontrol Science · doi:10.4265/bio.16.69 · Cited by 120

The role of chelators in preventing biofilm formation and catheter-related bloodstream infections

RAAD, I. I., Fang, X., Keutgen, X. M., Jiang, Y., Sherertz, R. J., & Hachem, R. Y. (2008) · Current Opinion in Infectious Diseases · doi:10.1097/qco.0b013e32830634d8 · Cited by 118

Potential Emergence of Multi-quorum Sensing Inhibitor Resistant (MQSIR) Bacteria

Koul, S., Prakash, J., Mishra, A., & Kalia, V. C. (2015) · Indian Journal of Microbiology · doi:10.1007/s12088-015-0558-0 · Cited by 118

Antioxidant, antimicrobial and anti-quorum sensing activities of Rubus rosaefolius phenolic extract

OLIVEIRA, B. D., Rodrigues, A. C., CARDOSO, B. M. I., Ramos, A. L. C. C., Bertoldi, M. C., Taylor, J. G., da Cunha, L. R., & Pinto, U. M. (2016) · Industrial Crops and Products · doi:10.1016/j.indcrop.2016.01.037 · Cited by 118

Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance

Quave, C. L., Lyles, J. T., Kavanaugh, J. S., Nelson, K., Parlet, C. P., Crosby, H. A., Heilmann, K. P., & Horswill, A. R. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136486 · Cited by 117

Iron-Responsive Regulation of Biofilm Formation in Staphylococcus aureus Involves Fur-Dependent and Fur-Independent Mechanisms

Johnson, M., Cockayne, A., Williams, P. H., & Morrissey, J. A. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.23.8211-8215.2005 · Cited by 117

Isolation and characterization of coliforms from glacial ice and water in Canada's High Arctic

Dancer, S. J., Shears, P., & Platt, D. J. (1997) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.1997.tb03590.x · Cited by 110

The Role of Efflux and Physiological Adaptation in Biofilm Tolerance and Resistance

Acker, H. V., & Coenye, T. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.r115.707257 · Cited by 108

Screening of antibiotic resistant inhibitors from local plant materials against two different strains of Staphylococcus aureus

Darwish, R. M., Aburjai, T. A., Al-Khalil, S. I., & Mahafzah, A. M. (2002) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(01)00411-1 · Cited by 104

Effect of biofilm culture upon the susceptibility of Staphylococcus epidermidis to tobramycin

Duguid, I. G., Evans, E., Brown, M. R., & Gilbert, P. (1992) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/30.6.803 · Cited by 103

The effects of ferulic and salicylic acids on Bacillus cereus and Pseudomonas fluorescens single- and dual-species biofilms

Lemos, M., Borges, A. D. S., Teodósio, J. S., Araújo, P. A., Mergulhão, F. J., Melo, L. F., & Simões, M. V. (2013) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2013.06.011 · Cited by 102

Antioxidant and antidiabetic activities of 11 herbal plants from Hyrcania region, Iran

Dehghan, H., Sarrafi, Y., & Salehi, P. (2015) · Journal of Food and Drug Analysis · doi:10.1016/j.jfda.2015.06.010 · Cited by 100

Quorum sensing inhibitors: a patent overview

Pan, J., & Ren, D. (2009) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543770903222293 · Cited by 100

Small molecules are natural triggers for the disassembly of biofilms

Oppenheimer‐Shaanan, Y., Steinberg, N., & Kolodkin‐Gal, I. (2013) · Trends in Microbiology · doi:10.1016/j.tim.2013.08.005 · Cited by 98

Effects of ginseng onPseudomonas aeruginosamotility and biofilm formation

Wu, H. W., Lee, B., Yang, L., Wang, H., Givskov, M., Molin, S., Høiby, N., & Song, Z. (2011) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2011.00787.x · Cited by 95

Comparison of Techniques and Solvents on the Antimicrobial and Antioxidant Potential of Extracts from Acacia dealbata and Olea europaea

Borges, A., José, H., Homem, V., & Simões, M. (2020) · Antibiotics · doi:10.3390/antibiotics9020048 · Cited by 184

The Antibacterial and Wound Healing Properties of Natural Products: A Review on Plant Species with Therapeutic Potential against Staphylococcus aureus Wound Infections

Morguette, A. E. B., Bartolomeu-Gonçalves, G., Andriani, G. M., Bertoncini, G. E. S., de Castro, I. M., de Almeida Spoladori, L. F., Bertão, A. M. S., Tavares, E. R., Yamauchi, L. M., & Yamada-Ogatta, S. F. (2023) · Plants · doi:10.3390/plants12112147 · Cited by 31