Role of the tumor microenvironment in tumor progression and the clinical applications (Review)

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Chemokines

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

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The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

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Met, metastasis, motility and more

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Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

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Inhibitory effect of tumor cell-derived lactic acid on human T cells

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Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

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VEGF contributes to postnatal neovascularization by mobilizing bone marrow‐derived endothelial progenitor cells

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Direct signaling between platelets and cancer cells induces an epithelial–mesenchymal-like transition and promotes metastasis

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Collagen reorganization at the tumor-stromal interface facilitates local invasion

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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

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Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition

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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

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Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

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ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis

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A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

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Autophagy: dual roles in life and death?

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TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4

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Stromal Fibroblasts in Cancer: A Novel Tumor-Promoting Cell Type

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Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

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Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

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CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3

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The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

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TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis

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Podosomes: adhesion hot-spots of invasive cells

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Transcriptional regulation of cell polarity in EMT and cancer

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Foot and mouth: podosomes, invadopodia and circular dorsal ruffles

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