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Cited by 495

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

A Possible Protective Effect of Nut Consumption on Risk of Coronary Heart Disease: The Adventist Health Study

Fraser, Gary E.·1992·Archives of Internal Medicine
DOI 10.1001/archinte.1992.00400190054010
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Abstract

bkground.— Although dietary factors are suspected to be important determinants of coronary heart disease (CHD) risk, the direct evidence is relative-lse. Methods.— The Adventist Health Study is a prospective cohort investigation of 31 208 non-Hispanic white California Seventh-Day Adventists. Extensive dietary information was obtained at baseline, along with the values of traditional coronary risk factors. These were related to risk of definite fatal CHD or definite nonfatal- dial infarction. Results.— Subjects who consumed nuts frequently (more than four times per week) experienced substantially fewer definite fatal CHD events (relative risk, 0.52; 95% confidence interval [CI], 0.36 to 0.76) and definite nonfatal myocardial infarctions (relative risk, 0.49; 95% CI, 0.28 to 0.85), when compared with those who consumed nuts less than once per week. These findings persisted on covariate adjustment and were seen in almost all of 16 different subgroups of the population. Subjects who usually consumed whole wheat bread also experienced lower rates of definite nonfatal myocardial infarction (relative risk, 0.56; 95% CI, 0.35 to 0.89) and definite fatal CHD (relative risk, 0.89; 95% CI, 0.60 to 1.33) when compared with those who usually ate white bread. Men who ate beef at least three times each week had a higher risk of definite fatal CHD (relative risk, 2.31; 95% CI, 1.11 to 4.78), but this effect was not seen in women or for the nonfatal myocardial infarction end point. Conclusion.— Our data strongly suggest that the frequent consumption of nuts may protect against risk of CHD events. The favorable fatty acid profile of many nuts is one possible explanation for such an effect. (Arch Intern Med. 1992;152:1416-1424)

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Metadata

Authors
Fraser, G. E.
Venue
Archives of Internal Medicine
Publisher
American Medical Association (AMA)
Published
1992-07-01
Volume
152
Issue
7
Pages
1416
ISSN
0003-9926 (ISSN-L)
DOI
10.1001/archinte.1992.00400190054010
OpenAlex
W4294991331
Cited by
495
References
2
FWCI
6.89
Type
journal article
Language
en
Open access
closed

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