Intracrine androgen biosynthesis, metabolism and action revisited

Schiffer, Lina, Arlt, Wiebke, Storbeck, Karl-Heinz·2018·Molecular and Cellular Endocrinology

Cites (349)

Items 201–330 of 330

  1. Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation
    Irina Grishkovskaya, G.V. Avvakumov, Geoffrey L. Hammond, Maria Graziella Catalano, Yves A. Muller · 2002 · Journal of Biological Chemistry
  2. Updated survey of the steroid-converting enzymes in human adipose tissues
    Tchernof, André, Mansour, Mohamed Fouad, Pelletier, Mélissa, Boulet, Marie-Michèle, Nadeau, Mélanie, Luu-The, Van · 2015 · The Journal of Steroid Biochemistry and Molecular Biology
  3. Origin of Substrate Specificity of Human and Rat 17 -Hydroxysteroid Dehydrogenase Type 1, Using Chimeric Enzymes and Site-Directed Substitutions
    Terhi Puranen, Matti H. POUTANEN, Debashis Ghosh, Reijo Vihko, Pirkko Vihko · 1997 · Endocrinology
  4. Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS
    Sánchez-Guijo, Alberto, Oji, Vinzenz, Hartmann, Michaela F., Traupe, Heiko, Wudy, Stefan A. · 2015 · Journal of Lipid Research
  5. The intracrinology of breast cancer
    Keely May McNamara, Hironobu Sasano · 2014 · The Journal of Steroid Biochemistry and Molecular Biology
  6. SRD5B1 (AKR1D1) gene analysis in Δ4-3-oxosteroid 5β-reductase deficiency: evidence for primary genetic defect
    Gonzales, Emmanuel, Cresteil, Danièle, Baussan, Christiane, Dabadie, Alain, Gerhardt, Marie-Françoise, Jacquemin, Emmanuel · 2004 · Journal of Hepatology
  7. 11β-Hydroxyandrostenedione: downstream metabolism by 11βHSD, 17βHSD and SRD5A produces novel substrates in familiar pathways
    Swart, Amanda C., Storbeck, Karl-Heinz · 2015 · Molecular and Cellular Endocrinology
  8. Metabolism of Epitestosterone in Man1
    Hildegard Wilson, Mortimer B. Lipsett · 1966 · The Journal of Clinical Endocrinology & Metabolism
  9. Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer
    Elahe A. Mostaghel, Ailin Zhang, Susana Hernández, Brett T. Marck, Xiaotun Zhang, Daniel Tamae, Heather E. Biehl, Maria Tretiakova, Jon Bartlett, John M Burns et al. · 2018 · Clinical Cancer Research
  10. Expression and activity of steroid aldoketoreductases 1C in omental adipose tissue are positive correlates of adiposity in women
    Blouin, Karine, Blanchette, Sophie, Richard, Christian, Dupont, Pierre, Luu-The, Van, Tchernof, André · 2005 · American Journal of Physiology-Endocrinology and Metabolism
  11. Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers.
    Tatsuo Kanda, Xia Jiang, Osamu Yokosuka · 2014 · PubMed
  12. Profiling adrenal 11β-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC2-MS/MS quantification of 11β-hydroxytestosterone, 11keto-testosterone and 11keto-dihydrotestosterone
    du Toit, Therina, Bloem, Liezl M., Quanson, Jonathan L., Ehlers, Riaan, Serafin, Antonio M., Swart, Amanda C. · 2017 · The Journal of Steroid Biochemistry and Molecular Biology
  13. Transcription of the Human Genes for Cytochrome P450scc and P450c17 Is Regulated Differently in Human Adrenal NCI-H295 Cells Than in Mouse Adrenal Y1 Cells
    H. Rodriguez · 1997 · The Journal of Clinical Endocrinology & Metabolism
  14. Profiling intact steroid sulfates and unconjugated steroids in biological fluids by liquid chromatography-tandem mass spectrometry (LC-MS-MS)
    Galuska, Christina E., Hartmann, Michaela F., Sánchez-Guijo, Alberto, Bakhaus, Katharina, Geyer, Joachim, Schuler, Gerhard, Zimmer, Klaus-Peter, Wudy, Stefan A. · 2013 · The Analyst
  15. Enhanced expression of organic anion transporting polypeptides (OATPs) in androgen receptor-positive prostate cancer cells: possible role of OATP1A2 in adaptive cell growth under androgen-depleted conditions
    Arakawa, Hiroshi, Nakanishi, Takeo, Yanagihara, Chihiro, Nishimoto, Tomohiro, Wakayama, Tomohiko, Mizokami, Atsushi, Namiki, Mikio, Kawai, Keiichi, Tamai, Ikumi · 2012 · Biochemical Pharmacology
  16. Multiple roles for UDP-glucuronosyltransferase (UGT)2B15 and UGT2B17 enzymes in androgen metabolism and prostate cancer evolution
    Gauthier-Landry, Louis, Bélanger, Alain, Barbier, Olivier · 2015 · The Journal of Steroid Biochemistry and Molecular Biology
  17. Biological Esterification of Steroids
    R. B. Hochberg · 1998 · Endocrine Reviews
  18. Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development
    Walter L. Miller, Richard Joseph Auchus · 2012 · Seminars in Reproductive Medicine
  19. Nonhuman primates as models for human adrenal androgen production: Function and dysfunction
    David Howard Abbott, Ian M. Bird · 2008 · Reviews in Endocrine and Metabolic Disorders
  20. Analysis of glucuronide and sulfate steroids in urine by ultra-high-performance supercritical-fluid chromatography hyphenated tandem mass spectrometry
    Doué, Mickael, Dervilly-Pinel, Gaud, Pouponneau, Karinne, Monteau, Fabrice, Le Bizec, Bruno · 2015 · Analytical and Bioanalytical Chemistry
  21. Expression and roles of steroidogenic acute regulatory (StAR) protein in 'non-classical', extra-adrenal and extra-gonadal cells and tissues
    Anuka, Eli, Gal, Michael, Stocco, Douglas M., Orly, Joseph · 2013 · Molecular and Cellular Endocrinology
  22. Androgen Deficiency and Defective Intracrine Processing of Dehydroepiandrosterone in Salivary Glands in Sjögren’s Syndrome
    Pauliina Porola, LIISA VIRKKI, BEATA D. PRZYBYLA, Mikael Laine, Tucker A. Patterson, Antti Pihakari, Yrjö Tapio Konttinen · 2008 · The Journal of Rheumatology
  23. Local Androgen Inactivation in Abdominal Visceral Adipose Tissue
    Karine Blouin, Christian Richard, Chantal Bélanger, Pierre Dupont, Marleen Daris, Philippe Yves Laberge, Van Luu-The, André Tchernof · 2003 · The Journal of Clinical Endocrinology & Metabolism
  24. Androgens and Glucuronidated Androgen Metabolites Are Associated with Metabolic Risk Factors in Men
    Liesbeth Vandenput, Dan Mellström, Mattias Lorentzon, Charlotte Swanson, Magnus K. Karlsson, John Brandberg, Lars Lönn, ERIC S. ORWOLL, Ulf Smith, Fernand Labrie et al. · 2007 · The Journal of Clinical Endocrinology & Metabolism
  25. Deletions of the Androgen-MetabolizingUGT2BGenes Have an Effect on Circulating Steroid Levels and Biochemical Recurrence after Radical Prostatectomy in Localized Prostate Cancer
    Geneviève Nadeau, Judith Bellemare, Étienne Audet‐Walsh, Christine Flageole, Shu‐Pin Huang, Bo‐Ying Bao, Pierre Douville, Patrick Caron, Yves Fradet, Louis Lacombe et al. · 2011 · The Journal of Clinical Endocrinology & Metabolism
  26. Aromatase in skeletal muscle
    Alexey A. Larionov, D.A Vasyliev, J. Ian Mason, A. Forbes Howie, Lev M. Berstein, William R. Miller · 2003 · The Journal of Steroid Biochemistry and Molecular Biology
  27. 11β-Hydroxyandrostenedione Returns to the Steroid Arena: Biosynthesis, Metabolism and Function
    Liezl M. Bloem, Karl‐Heinz Storbeck, Lindie Schloms, Amanda Cecilia Swart · 2013 · Molecules
  28. Sulfation of tibolone and tibolone metabolites by expressed human cytosolic sulfotransferases
    Falany, Josie L, Macrina, Nancy, Falany, Charles N · 2004 · The Journal of Steroid Biochemistry and Molecular Biology
  29. Human Δ4-3-oxosteroid 5β-reductase (AKR1D1) deficiency and steroid metabolism
    Palermo, Mario, Marazzi, Maria Grazia, Hughes, Beverly A., Stewart, Paul M., Clayton, Peter T., Shackleton, Cedric H.L. · 2008 · Steroids
  30. Steroid sulfatase inhibitors: promising new tools for breast cancer therapy?
    Geisler, Jürgen, Sasano, Hironobu, Chen, Shiuan, Purohit, Atul · 2011 · The Journal of Steroid Biochemistry and Molecular Biology
  31. 5β-Reduced steroids and human Δ4-3-ketosteroid 5β-reductase (AKR1D1)
    Chen, Mo, Penning, Trevor M. · 2014 · Steroids
  32. Oxidative metabolism of dehydroepiandrosterone (DHEA) and biologically active oxygenated metabolites of DHEA and epiandrosterone (EpiA) – Recent reports
    Laïla El Kihel · 2011 · Steroids
  33. Differential androgen and estrogen substrates specificity in the mouse and primates type 12 17β-hydroxysteroid dehydrogenase
    Pierre-Gilles Blanchard, Van Luu-The · 2007 · Journal of Endocrinology
  34. Cations Inhibit Specifically Type I 5α-Reductase Found in Human Skin
    Sugimoto, Yasuro, López-Solache, Irma, Labrie, Fernand, Luu-The, V.a.n. · 1995 · Journal of Investigative Dermatology
  35. Development of a liquid chromatography–tandem mass spectrometry method for the identification of natural androgen steroids and their conjugates in urine samples
    Buiarelli, F., Coccioli, F., Merolle, M., Neri, B., Terracciano, A. · 2004 · Analytica Chimica Acta
  36. Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1)
    Chen, Mo, Drury, Jason E., Penning, Trevor M. · 2011 · Steroids
  37. Genomic organization of a human 5β-reductase and its pseudogene and substrate selectivity of the expressed enzyme
    Annie Charbonneau, Van Luu The · 2001 · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
  38. The 5α-androstanedione pathway to dihydrotestosterone in castration-resistant prostate cancer
    Sharifi, Nima · 2012 · Journal of Investigative Medicine
  39. Structural Characterization and Expression of the Human Dehydroepiandrosterone Sulfotransferase Gene
    VAN LUU-THE, Isabelle Dufort, Nathalie Paquet, Guy Reimnitz, Fernand Labrie · 1995 · DNA and Cell Biology
  40. Advances in the analytical methodologies: profiling steroids in familiar pathways-challenging dogmas
    Bloem, Liezl M., Storbeck, Karl-Heinz, Swart, Pieter, du Toit, Therina, Schloms, Lindie, Swart, Amanda C. · 2015 · The Journal of Steroid Biochemistry and Molecular Biology
  41. Endogenous glucocorticoid analysis by liquid chromatography–tandem mass spectrometry in routine clinical laboratories
    James M. Hawley, Brian George Keevil · 2016 · The Journal of Steroid Biochemistry and Molecular Biology
  42. A steroidogenic pathway for sulfonated steroids: The metabolism of pregnenolone sulfate
    Jens Neunzig, Alberto Sánchez‐Guijo, A. Mosa, Michaela F. Hartmann, Joachim Geyer, Stefan Alexander Wudy, Rita Bernhardt · 2014 · The Journal of Steroid Biochemistry and Molecular Biology
  43. New frontiers in androgen biosynthesis and metabolism
    Penning, Trevor M · 2010 · Current Opinion in Endocrinology, Diabetes & Obesity
  44. 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes
    Nasiri, Maryam, Nikolaou, Nikolaos, Parajes, Silvia, Krone, Nils P., Valsamakis, George, Mastorakos, George, Hughes, Beverly, Taylor, Angela, Bujalska, Iwona J., Gathercole, Laura L. et al. · 2015 · Endocrinology
  45. Expression of the androgen metabolizing enzyme UGT2B15 in adipose tissue and relative expression measurement using a competitive RT-PCR method
    Tchernof, André, Lévesque, Éric, Beaulieu, Martin, Couture, Patrick, Després, Jean‐Pierre, Hum, Dean W., Bélanger, Alain · 1999 · Clinical Endocrinology
  46. Human Cytosolic Hydroxysteroid Dehydrogenases of the Aldo-ketoreductase Superfamily Catalyze Reduction of Conjugated Steroids
    Jin, Yi, Duan, Ling, Lee, Seon Hwa, Kloosterboer, Helenius J., Blair, Ian A., Penning, Trevor M. · 2009 · Journal of Biological Chemistry
  47. Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo–keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway
    Jin, Yi, Mesaros, A. Clementina, Blair, Ian A., Penning, Trevor M. · 2011 · Biochemical Journal
  48. 17β-Hydroxysteroid Dehydrogenase 3 Deficiency in Women<sup>1</sup>
    Mendonca, Berenice B., Arnhold, Ivo J. P., Bloise, Walter, Andersson, Steffan, Russell, David W., Wilson, Jean D. · 1999 · The Journal of Clinical Endocrinology &amp; Metabolism
  49. Testosterone synthesized in cultured human SZ95 sebocytes derives mainly from dehydroepiandrosterone
    Chen, WenChieh, Tsai, Shaw‐Jenq, Sheu, Hamm‐Ming, Tsai, Jih‐Chien, Zouboulis, Christos C. · 2010 · Experimental Dermatology
  50. Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency
    Alberto Sánchez‐Guijo, Jens Neunzig, Adrian Gerber, Vinzenz Oji, Michaela F. Hartmann, Hans-Christian Schuppe, Heiko Traupe, Rita Bernhardt, Stefan Alexander Wudy · 2016 · Molecular and Cellular Endocrinology
  51. Androgen receptor signaling in hepatocellular carcinoma and pancreatic cancers
    Tatsuo, Kanda, Xia · 2014 · Acta Scientiarum Naturalium Universitatis Sunyatseni
  52. Sex- and age-related changes in epitestosterone in relation to pregnenolone sulfate and testosterone in normal subjects
    Havlíková, Helena, Hill, Martin, Hampl, Richard, Stárka, Luboš · 2002 · The Journal of Clinical Endocrinology &amp; Metabolism
  53. Endometrial Intracrinology—Generation of an estrogen-dominated microenvironment in the secretory phase of women
    Gibson, D. A., McInnes, K. J., Critchley, H. O. D., Saunders, P. T. K. · 2013 · The Journal of Clinical Endocrinology &amp; Metabolism
  54. Fetal hormones and sexual differentiation
    Sobel, Vivian, Zhu, Yuan-Shan, Imperato-McGinley, Julianne · 2004 · Obstetrics and Gynecology Clinics of North America
  55. Healthy human salivary glands contain a DHEA-sulphate processing intracrine machinery, which is deranged in primary Sjogren's syndrome
    Spaan, Michelle, Porola, Pauliina, Laine, Mikael, Rozman, Blaz, Azuma, Masayuki, Konttinen, Yrjö T. · 2009 · Journal of Cellular and Molecular Medicine
  56. Relationships of sex steroid hormone levels in benign and cancerous breast tissue and blood: a critical appraisal of current science
    Stanczyk, Frank Z., Mathews, Brett W., Sherman, Mark E. · 2015 · Steroids
  57. Metabolomic Biomarkers in Urine of Cushing’s Syndrome Patients
    Alicja Kotłowska, Tomasz Puzyn, Krzysztof Sworczak, Piotr Stepnowski, Piotr Szefer · 2017 · International Journal of Molecular Sciences
  58. The Steroid Metabolome in the Isolated Ovarian Follicle and Its Response to Androgen Exposure and Antagonism
    Marie Lebbe, ANGELA E. R. TAYLOR, Jenny A. Visser, Jackson Kirkman‐Brown, Teresa K. Woodruff, Wiebke Arlt · 2017 · Endocrinology
  59. Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia
    Keith D. Kaufman, Rodney P. R. Dawber · 1999 · Expert Opinion on Investigational Drugs
  60. Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential
    MARK P. THOMAS, Barry V. L. Potter · 2015 · The Journal of Steroid Biochemistry and Molecular Biology
  61. Biosynthesis of dihydrotestosterone by a pathway that does not require testosterone as an intermediate in the SZ95 sebaceous gland cell line
    Samson, Melanie, Labrie, Fernand, Zouboulis, Christos C., Luu-The, Van · 2010 · Journal of Investigative Dermatology
  62. The identification, quantification and possible origin of non-polar conjugates in human plasma
    D.L. Jones, Vivian H.T. James · 1985 · Journal of Steroid Biochemistry
  63. An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin
    Cherkasov, Artem, Ban, Fuqiang, Santos-Filho, Osvaldo, Thorsteinson, Nels, Fallahi, Magid, Hammond, Geoffrey L. · 2008 · Journal of Medicinal Chemistry
  64. Steroid sulfatase deficiency and androgen activation before and after puberty
    Idkowiak, Jan, Taylor, Angela E., Subtil, Sandra, O'Neil, Donna M., Vijzelaar, Raymon, Dias, Renuka P., Amin, Rakesh, Barrett, Timothy G., Shackleton, Cedric H. L., Kirk, Jeremy M. W. et al. · 2016 · The Journal of Clinical Endocrinology &amp; Metabolism
  65. Detection, synthesis and characterization of metabolites of steroid hormones conjugated with cysteine
    Fabregat, Andreu, Kotronoulas, Aristotelis, Marcos, Josep, Joglar, Jesús, Alfonso, Ignacio, Segura, Jordi, Ventura, Rosa, Pozo, Oscar J. · 2013 · Steroids
  66. 17-Hydroxylase/C17, 20-lyase (CYP17) is not the enzyme responsible for side-chain cleavage of cortisol and its metabolites
    Shackleton, Cedric H.L., Neres, Marcos S., Hughes, Beverly A., Stewart, Paul M., Kater, Claudio E. · 2008 · Steroids
  67. Reference ranges of 17-hydroxyprogesterone, DHEA, DHEAS, androstenedione, total and free testosterone determined by TurboFlow-LC–MS/MS and associations to health markers in 304 men
    Damgaard–Olesen, A., Johannsen, T.H., Holmboe, S.A., Søeborg, T., Petersen, J.H., Andersson, AM., Aadahl, M., Linneberg, A., Juul, A. · 2016 · Clinica Chimica Acta
  68. Steroid metabolism in breast cancer: Where are we and what are we missing?
    Donita Africander, Karl‐Heinz Storbeck · 2017 · Molecular and Cellular Endocrinology
  69. Molecular Targets of Androgen Signaling that Characterize Skeletal Muscle Recovery and Regeneration
    James G. MacKrell, Benjamin C. Yaden, Heather A. Bullock, Keyue Chen, Pamela K. Shetler, Henry U. Bryant, Venkatesh Krishnan · 2015 · Nuclear Receptor Signaling
  70. Androstane-3α,17β-Diol Glucuronide as a Steroid Correlate of Visceral Obesity in Men*
    André Tchernof, Fernand Labrie, Alain Bélanger, Denis Prud’homme, Claude Bouchard, Angelo Tremblay, André Nadeau, Jean‐Pierre Després · 1997 · The Journal of Clinical Endocrinology & Metabolism
  71. Genotype-dependent metabolism of exogenous testosterone - new biomarkers result in prolonged detectability
    Piper, Thomas, Schänzer, Wilhelm, Thevis, Mario · 2016 · Drug Testing and Analysis
  72. Characterization of 17α-hydroxysteroid dehydrogenase activity (17α-HSD) and its involvement in the biosynthesis of epitestosterone
    Bellemare, Véronique, Faucher, Frédérick, Breton, Rock, Luu-The, Van · 2005 · BMC Biochemistry
  73. Androstanediol glucuronide production in human liver, prostate, and skin. Evidence for the importance of the liver in 5 alpha-reduced androgen metabolism
    Roger S. Rittmaster, H Zwicker, D L Thompson, G P Konok, Richard W. Norman · 1993 · The Journal of Clinical Endocrinology & Metabolism
  74. Age-specific changes in sex steroid biosynthesis and sex development
    Krone, Nils, Hanley, Neil A., Arlt, Wiebke · 2007 · Best Practice &amp; Research Clinical Endocrinology &amp; Metabolism
  75. Metabolism of 19-methyl-substituted steroids by human placental aromatase
    Beusen, Denise D., Carrell, H. L., Covey, Douglas F. · 1987 · Biochemistry
  76. Measurement of inhibin concentrations in men: study of changes after castration and comparison with androgen levels in testicular tissue, spermatic venous blood, and peripheral venous blood
    ISHIDA, H., TASHIRO, H., WATANABE, M., FUJII, N., IMAMURA, K., MINOWADA, S., SHINOHARA, M., FUKUTANI, K., ASO, Y., DE KRETSER, D. M. · 1990 · The Journal of Clinical Endocrinology &amp; Metabolism
  77. Steroid metabolism in testis tissue: The metabolism of pregnenolone, pregnenolone sulfate, dehydroepiandrosterone and dehydroepiandrosterone sulfate in human and boar testes in vitro
    Aimo Ruokonen · 1978 · Journal of Steroid Biochemistry
  78. Role of Microsomal Retinol/Sterol Dehydrogenase-Like Short-Chain Dehydrogenases/Reductases in the Oxidation and Epimerization of 3α-Hydroxysteroids in Human Tissues
    Olga V. Belyaeva, Sergei V. Chetyrkin, Amy L. Clark, Natalia V. Kostereva, Karen Sterling SantaCruz, Bibie M. Chronwall, Natalia Y. Kedishvili · 2007 · Endocrinology
  79. Expression of cytochrome P450 3A4 and its clinical significance in human prostate cancer
    Fujimura, Tetsuya, Takahashi, Satoru, Urano, Tomohiko, Kumagai, Jinpei, Murata, Taro, Takayama, Kenichi, Ogushi, Tetsuo, Horie-Inoue, Kuniko, Ouchi, Yasuyoshi, Kitamura, Tadaichi et al. · 2009 · Urology
  80. The cortisol-cortisone shuttle and the apparent specificity of glucocorticoid and mineralocorticoid receptors
    Christopher R.W. Edwards, Paul M. Stewart · 1991 · The Journal of Steroid Biochemistry and Molecular Biology
  81. Identification and immunohistochemical localization of Sulfotransferase 2B1b (SULT2B1b) in human lung
    Dongning He, Andra R. Frost, Charles Napoleon Falany · 2005 · Biochimica et Biophysica Acta (BBA) - General Subjects
  82. 17α-Hydroxylase (CYP17) Expression and Subsequent Androstenedione Production in the Human Ovary
    Patel, Satin S., Beshay, Victor E., Escobar, Julian C., Carr, Bruce R. · 2010 · Reproductive Sciences
  83. Role of Dehydroepiandrosterone Sulfate as a Prehormone for Ovarian Steroidogenesis
    Ray V. Haning, Charles W. Austin, Ian H. Carlson, Donna L. Kuzma, William J. Zweibel · 1985 · Obstetrical & Gynecological Survey
  84. Estrone sulfate transport and steroid sulfatase activity in colorectal cancer: implications for hormone replacement therapy
    Gilligan, Lorna C., Gondal, Ali, Tang, Vivien, Hussain, Maryam T., Arvaniti, Anastasia, Hewitt, Anne-Marie, Foster, Paul A. · 2017 · Frontiers in Pharmacology
  85. Androgen glucuronides analysis by liquid chromatography tandem-mass spectrometry: could it raise new perspectives in the diagnostic field of hormone-dependent malignancies?
    Kalogera, Eleni, Pistos, Constantinos, Provatopoulou, Xeni, Athanaselis, Sotirios, Spiliopoulou, Chara, Gounaris, Antonia · 2013 · Journal of Chromatography B
  86. Analysis of the microRNA expression profile of normal human dermal papilla cells treated with 5α-dihydrotestosterone
    MYUNG JOO LEE, Hwa Jun Cha, Kyung Mi Lim, Ok-Kyu Lee, Seunghee Bae, Chun‐Ho Kim, Kee‐Ho Lee, Yu Na Lee, Kyu Joong Ahn, Sungkwan An · 2012 · Molecular Medicine Reports
  87. Determination of <sup>13</sup>C/<sup>12</sup>C ratios of urinary epitestosterone and its main metabolites 5α‐ and 5β‐androstane‐3α, 17α‐diol
    Piper, Thomas, Riemann, Phillip, Opfermann, Georg, Mareck, Ute, Geyer, Hans, Vajiala, Graziela, Flenker, Ulrich, Schänzer, Wilhelm · 2009 · Drug Testing and Analysis
  88. Adrenarche is associated with decreased 3β-hydroxysteroid dehydrogenase expression in the adrenal reticularis
    Gell, J. S., Atkins, B., Margraf, L., Mason, J. I., Sasano, H., Rainey, W. E., Carr, B. R. · 1996 · Endocrine Research
  89. Effects of sex hormone-binding globulin (SHBG) on androgen bioactivity in vitro
    Laurent, Michaël R., Helsen, Christine, Antonio, Leen, Schollaert, Dieter, Joniau, Steven, Vos, Michel J., Decallonne, Brigitte, Hammond, Geoffrey L., Vanderschueren, Dirk, Claessens, Frank · 2016 · Molecular and Cellular Endocrinology
  90. Metabolism of progesterone and testosterone in human parotid and submandibular salivary glands in vitro
    Tomas Blom, Anita Ojanotko-Harri, Merja Anneli Laine · 1993 · The Journal of Steroid Biochemistry and Molecular Biology
  91. Human UDP-glucuronosyltransferase, UGT1A8, glucuronidates dihydrotestosterone to a monoglucuronide and further to a structurally novel diglucuronide
    Murai, Takahiro, Samata, Naozumi, Iwabuchi, Haruo, Ikeda, Toshihiko · 2006 · Drug Metabolism and Disposition
  92. Testosterone synthesis in patients with 17β-hydroxysteroid dehydrogenase 3 deficiency
    Werner, R., Kulle, A., Sommerfeld, I., Riepe, F.G., Wudy, S., Hartmann, M.F., Merz, H., Döhnert, U., Bertelloni, S., Holterhus, P.-M. et al. · 2012 · Sexual Development
  93. 17β-Estradiol Enhances the Production of Granulocyte-Macrophage Colony-Stimulating Factor in Human Keratinocytes
    Kanda, Naoko, Watanabe, Shinichi · 2004 · Journal of Investigative Dermatology
  94. Association of Uridine Diphosphate-Glucuronosyltransferase 2B Gene Variants with Serum Glucuronide Levels and Prostate Cancer Risk
    Delores J. Grant, Cathrine Hoyo, Shannon Oliver, Leah Gerber, Katie Shuler, Elizabeth Ellen Calloway, Alexis R. Freedland, Megan E. McPhail, Jonathan N. Livingston, Ricardo Micheler Richardson et al. · 2012 · Genetic Testing and Molecular Biomarkers
  95. Metabolic Effects of 12-Month Percutaneous Dehydroepiandrosterone Replacement Therapy in Postmenopausal Women
    Pierre Diamond, Lionel Cusan, J.-L. Gomez, A. Bèlanger, Fernand Labrie · 1997 · Obstetrical & Gynecological Survey
  96. Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry
    Zang, Tianzhu, Tamae, Daniel, Mesaros, Clementina, Wang, Qingqing, Huang, Meng, Blair, Ian A., Penning, Trevor M. · 2017 · The Journal of Steroid Biochemistry and Molecular Biology
  97. Reporting and managing elevated testosterone/epitestosterone ratios–novel aspects after five years' experience
    Mareck, Ute, Geyer, Hans, Fußhöller, Gregor, Schwenke, Anne, Haenelt, Nadine, Piper, Thomas, Thevis, Mario, Schänzer, Wilhelm · 2010 · Drug Testing and Analysis
  98. Steroid hydroxylation by human fetal CYP3A7 and human NADPH-cytochrome P450 reductase coexpressed in insect cells using baculovirus.
    S. Ohmori, N Fujiki, Hiromitsu Nakasa, Hiroyoshi Nakamura, I Ishii, K. Itahashi, M Kitada · 1998 · PubMed
  99. Expression of 11β-hydroxysteroid dehydrogenase type 2 (11βHSD-2) in the developing human adrenal gland and human adrenal cortical carcinoma and adenoma
    Coulter, Catherine L, Smith, Robin E, Stowasser, Michael, Sasano, Hironobu, Krozowski, Zygmunt S, Gordon, Richard D · 1999 · Molecular and Cellular Endocrinology
  100. Association analysis between the polymorphisms of HSD17B5 and HSD17B6 and risk of polycystic ovary syndrome in Chinese population
    Rong Ju, Wei Wu, Juan Fei, Yufeng Qin, Qiuqin Tang, Di Wu, Yankai Xia, Jie Wu, Xinru Wang · 2014 · European Journal of Endocrinology
  101. The steroid metabolite 16(β)-OH-androstenedione generated by CYP21A2 serves as a substrate for CYP19A1
    Jens Neunzig, Mohammed Milhim, Lina Schiffer, Yogan Khatri, Josef Zapp, Alberto Sánchez‐Guijo, Michaela F. Hartmann, Stefan Alexander Wudy, Rita Bernhardt · 2017 · The Journal of Steroid Biochemistry and Molecular Biology
  102. The murine 3β-hydroxysteroid dehydrogenase multigene family: Structure, function and tissue-specific expression
    Payne, Anita H., Clarke, Trent R., Bain, Paul A. · 1995 · The Journal of Steroid Biochemistry and Molecular Biology
  103. Structure-function relationships and molecular genetics of the 3β-hydroxysteroid dehydrogenase gene family
    Simard, Jacques, Sanchez, Rocio, Durocher, Francine, Rhéaume, Eric, Turgeon, Carl, Labrie, Yvan, Luu-The, Van, Mebarki, Farida, Morel, Yves, de Launoit, Yvan et al. · 1995 · The Journal of Steroid Biochemistry and Molecular Biology
  104. Steroid fatty acid esters in adrenals and plasma: effects of ACTH
    Benoît Bélanger, S. Caron, A. Bèlanger, A. Dupont · 1990 · Journal of Endocrinology
  105. Characterization of the Adrenal Cytochrome P450C17 in the Hamster, a Small Animal Model for the Study of Adrenal Dehydroepiandrosterone Biosynthesis
    Mario Cloutier, A. Fleury, Jean Courtemanche, Lyne Ducharme, J. Ian Mason, Jean‐Guy Lehoux · 1997 · DNA and Cell Biology
  106. Androgenic 17 beta-hydroxysteroid dehydrogenase activity of expressed rat type I 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase
    de Launoit, Y, Simard, J, Durocher, F, Labrie, F · 1992 · Endocrinology
  107. In the zone: understanding zona reticularis function and its transformation by adrenarche
    Bird, Ian M · 2012 · Journal of Endocrinology
  108. Selective inhibition of human 3β-hydroxysteroid dehydrogenase type 1 as a potential treatment for breast cancer
    Thomas, James L., Bucholtz, Kevin M., Kacsoh, Balint · 2011 · The Journal of Steroid Biochemistry and Molecular Biology
  109. Sjögren’s syndome and extragonadal sex steroid formation: A clue to a better disease control?
    Yrjö Tapio Konttinen, Vasily Stegaev, Ahmed Al‐Samadi, Pauliina Porola, J. H. Hietanen, Mari Ainola · 2014 · The Journal of Steroid Biochemistry and Molecular Biology
  110. Assay reproducibility of serum androgen measurements using liquid chromatography–tandem mass spectrometry
    Trabert, Britton, Xu, Xia, Falk, Roni T., Guillemette, Chantal, Stanczyk, Frank Z., McGlynn, Katherine A. · 2016 · The Journal of Steroid Biochemistry and Molecular Biology
  111. Lipoproteins: Carriers of dehydroepiandrosterone fatty acid esters in human serum
    R Roy, A. Bèlanger · 1989 · Journal of Steroid Biochemistry
  112. Fatty acid esters of steroids: Synthesis and metabolism in lipoproteins and adipose tissue
    Veera Vihma, Matti J. Tikkanen · 2011 · The Journal of Steroid Biochemistry and Molecular Biology
  113. Dehydroepiandrosterone-fatty acid esters in human plasma: formation, transport and delivery to steroid target tissues.
    B. F. Lavallée, Provost Pr, Roy R · 1996 · PubMed
  114. P0188 SRD5B1 (AKR1D1) GENE ANALYSIS IN DELTA4???3-OXOSTEROID 5BETA-REDUCTASE DEFICIENCY: EVIDENCE FOR PRIMARY GENETIC DEFECT
    Emmanuel M. Gonzales, Danièle Cresteil, Christiane Baussan, A. Dabadie, M. Gerhardt, Emmanuel Jacquemin · 2004 · Journal of Pediatric Gastroenterology and Nutrition
  115. Quantitative determination of dehydroepiandrosterone fatty acyl esters in human female adipose tissue and serum using mass spectrometric methods
    Wang, Feng, Koskela, Anja, Hämäläinen, Esa, Turpeinen, Ursula, Savolainen-Peltonen, Hanna, Mikkola, Tomi S., Vihma, Veera, Adlercreutz, Herman, Tikkanen, Matti J. · 2011 · The Journal of Steroid Biochemistry and Molecular Biology
  116. Repeated glucuronidation at one hydroxyl group leads to structurally novel diglucuronides of steroid sex hormones
    Murai, Takahiro, Iwabuchi, Haruo, Ikeda, Toshihiko · 2005 · Drug Metabolism and Pharmacokinetics
  117. Fatty Acyl Esterification and Deesterification of 17β-Estradiol in Human Breast Subcutaneous Adipose Tissue
    Feng Wang, Veera Vihma, Maija Badeau, Hanna M. Savolainen-Peltonen, Marjut Leidenius, Tomi S. Mikkola, Ursula Turpeinen, Esa K Hämäläinen, Elina Ikonen, Kristiina Wähälä et al. · 2012 · The Journal of Clinical Endocrinology & Metabolism
  118. Production and metabolism of dihydrotestosterone in peripheral tissues
    Christopher Longcope, Samuel Edwin Fineberg · 1985 · Journal of Steroid Biochemistry
  119. How Do We Measure Hyperandrogenemia in Patients With PCOS?
    Brian George Keevil · 2014 · The Journal of Clinical Endocrinology & Metabolism
  120. Androgen and breast cancer
    Keely May McNamara, Hironobu Sasano · 2016 · Current Opinion in Endocrinology Diabetes and Obesity
  121. Metabolism of 19-methyl substituted steroids and a proposal for the third aromatase monooxygenation
    Douglas F. Covey, H. L. Carrell, Denise D. Beusen · 1987 · Steroids
  122. Phase Two Steroid Metabolism and Its Roles in Breast and Prostate Cancer Patients
    Keely May McNamara, Yasuhiro Nakamura, Yasuhiro Miki, Hironobu Sasano · 2013 · Frontiers in Endocrinology
  123. Steroid metabolism by normal and neoplastic parotid tissue
    O. Djøseland, A. de Besche, S. Hôglo, Paul S. Rennie · 1982 · Journal of Steroid Biochemistry
  124. Serum sex steroids and steroidogenesis-related enzyme expression in skeletal muscle during experimental weight gain in men
    Koji Sato, Dorit Samocha‐Bonet, David J. Handelsman, Satoshi Fujita, Gary Wittert, Leonie Kaye Heilbronn · 2014 · Diabetes & Metabolism
  125. Cloning and Expression of Hamster Adrenal Cytochrome P450C17 cDNA<sup>a</sup>
    CLOUTIER, MARIO, FLEURY, ALAIN, COURTEMANCHE, JEAN, DUCHARME, LYNE, MASON, J. IAN, LEHOUX, JEAN‐GUY · 1995 · Annals of the New York Academy of Sciences
  126. Evidence of Direct Conversion of Testosterone Sulfate to Estradiol 17-Sulfate by Human Placental Microsomes.
    Takashi K. Satoh, Kazuhiro Watanabe, Kaori Takanashi · 1992 · Journal of Pharmacobio-Dynamics
  127. Studies of the Guinea pig adrenal cytochrome P450c17 cDNA
    Tremblay, Yves, Bélanger, Alain, Fleury, Alain, Beaudoin, Claude, Provost, Pierre, Martineau, Isabelle · 1995 · Endocrine Research
  128. Beyond the C18 frontier: Androgen and glucocorticoid metabolism in breast cancer tissues
    Keely May McNamara, Hironobu Sasano · 2015 · Steroids
  129. A validated LC–MS/MS method for the sensitive quantitation of serum 7alpha hydroxy-, 7beta hydroxy- and 7keto-dehydroepiandrosterone using a novel derivatization reagent
    Yuyong Ke, Renaud Gonthier, Jean-Nicolas Simard, Fernand Labrie · 2016 · Steroids
  130. Contribution of mouse adrenal glands to intratumor androgens and growth of castration-resistant prostate cancer xenografts
    Mostaghel, Elahe A., Biehl, Heather, Hernandez, Susanna, Zhang, Ailin, Bartlett, Jon, Corey, Eva, Penning, Trevor M., Oksala, Riikka, True, Lawrence D., Nelson, Peter · 2017 · Journal of Clinical Oncology