Cited by 8,122Medical Image Segmentation TechniquesFunctional Brain Connectivity StudiesAdvanced MRI Techniques and Applications

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A fast diffeomorphic image registration algorithm

Ashburner, John·2007·NeuroImage

DOI 10.1016/j.neuroimage.2007.07.007

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Abstract

This paper describes DARTEL, which is an algorithm for diffeomorphic image registration. It is implemented for both 2D and 3D image registration and has been formulated to include an option for estimating inverse consistent deformations. Nonlinear registration is considered as a local optimisation problem, which is solved using a Levenberg-Marquardt strategy. The necessary matrix solutions are obtained in reasonable time using a multigrid method. A constant Eulerian velocity framework is used, which allows a rapid scaling and squaring method to be used in the computations. DARTEL has been applied to intersubject registration of 471 whole brain images, and the resulting deformations were evaluated in terms of how well they encode the shape information necessary to separate male and female subjects and to predict the ages of the subjects.

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Authors: Ashburner, J.
Affiliations: Wellcome Centre for Human Neuroimaging (GB)
Corresponding author: Ashburner, John
ORCID: Ashburner, John
Venue: NeuroImage
Publisher: Elsevier BV
Published: 2007-10
Volume: 38
Issue: 1
Pages: 95-113
ISSN: 1053-8119 (ISSN-L)
DOI: 10.1016/j.neuroimage.2007.07.007
OpenAlex: W2155298532
Cited by: 8,122
References: 35
Citations by year: 2026: 343 · 2025: 522 · 2024: 530 · 2023: 514 · 2022: 620 · 2021: 681 · 2020: 630 · 2019: 555 · 2018: 528 · 2017: 541 · 2016: 481 · 2015: 539 · 2014: 466 · 2013: 428 · 2012: 295
FWCI: 96.63
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: NeuroImage (publishedVersion)
PubMed (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
Funders: Wellcome Trust
Universiteit Maastricht
Topics: Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
Keywords: diffeomorphic registration, DARTEL, nonlinear registration, Levenberg-Marquardt algorithm, multigrid methods, scaling and squaring, whole-brain MRI, brain shape, sex classification, age prediction
MeSH terms: Algorithms, Artificial Intelligence, Brain, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Pattern Recognition, Automated, Sensitivity and Specificity, Subtraction Technique, Reproducibility of Results, Imaging, Three-Dimensional

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A fast diffeomorphic image registration algorithm

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