Cited by 689Memory Processes and InfluencesMemory and Neural MechanismsCognitive Functions and Memory

Dissociable correlates of recollection and familiarity within the medial temporal lobes

Ranganath, Charan, Yonelinas, Andrew P., Cohen, Michael X, Dy, Christine J., Tom, Sabrina M., D’Esposito, Mark·2004·Neuropsychologia

Abstract

Regions in the medial temporal lobes (MTL) have long been implicated in the formation of new memories for events, however, it is unclear whether different MTL subregions support different memory processes. Here, we used event-related functional magnetic resonance imaging (fMRI) to examine the degree to which two recognition memory processes-recollection and familiarity-were supported by different MTL subregions. Results showed that encoding activity in the rhinal cortex selectively predicted familiarity-based recognition, whereas, activity in the hippocampus and posterior parahippocampal cortex selectively predicted recollection. Collectively, these results support the view that different subregions within the MTL memory system implement unique encoding processes that differentially support familiarity and recollection.

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Crossref · 10.1016/j.neuropsychologia.2003.07.006

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Authors
Ranganath, C., Yonelinas, A. P., Cohen, M. X., Dy, C. J., Tom, S. M., & D’Esposito, M.
Affiliations
  • University of California, Davis (US)
  • University of California, Berkeley (US)
Venue
Neuropsychologia
Publisher
Elsevier BV
Published
2004-01
Volume
42
Issue
1
Pages
2-13
ISSN
0028-3932 (ISSN-L)
OpenAlex
W2103235389
Cited by
689
References
74
Citations by year
2026: 6 · 2025: 15 · 2024: 11 · 2023: 9 · 2022: 19 · 2021: 12 · 2020: 21 · 2019: 29 · 2018: 27 · 2017: 36 · 2016: 19 · 2015: 35 · 2014: 31 · 2013: 32 · 2012: 47
FWCI
16.61
Type
journal article
Language
en
Open access
closed
Locations
  • Neuropsychologia (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Johns Hopkins University
  • National Institute on Aging (R01AG015793, AG 15793, F32AG005863, AG05863)
  • National Institute of Mental Health (MH 59352, R01MH063901, MH 63901, R01MH059352)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
Keywords
recollection, familiarity, recognition memory, medial temporal lobe, rhinal cortex, hippocampus, parahippocampal cortex, memory encoding, event memory
MeSH terms
Adolescent, Adult, Cognition, Humans, Magnetic Resonance Imaging, Male, Memory, Oxygen, Psychomotor Performance, Mental Recall, Temporal Lobe, Prefrontal Cortex

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