The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Recent studies indicate that AKT also promotes survival by activating NF-κB (77-80”
From AKT Induces Transcriptional Activity of PU.1 through Phosphorylation-mediated Modifications within Its Transactivation Domain (2001) · cites this paper as [79]
In the citing paper
“This is mediated through phosphorylation-dependent inhibition of proteins associated with apoptosis, including Bad, caspase-9, and the transcription factor Forkhead (77-79”
From AKT Induces Transcriptional Activity of PU.1 through Phosphorylation-mediated Modifications within Its Transactivation Domain (2001) · cites this paper as [79]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Death Receptors: Signaling and Modulation
Ashkenazi, A., & Dixit, V. M. (1998) · Science · doi:10.1126/science.281.5381.1305 · Cited by 5,866
Ellis, L., Clauser, E., Morgan, D. O., Edery, M., Roth, R. A., & Rutter, W. J. (1986) · Cell · doi:10.1016/0092-8674(86)90786-5 · Cited by 1,070
Kasibhatla, S., Brunner, T., Genestier, L., Echeverri, F., Mahboubi, A., & Green, D. R. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80054-4 · Cited by 721
Research works printed but not linked: 40
- Alessi, 1996, Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase, FEBS Lett., 399, 333, 10.1016/S0014-5793(96)01370-1 · DOI · Paper page
- Anderson, 1998, Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily, Genomics, 47, 187, 10.1006/geno.1997.5122 · DOI
- Andjelkovic, 1997, Role of translocation in the activation and function of protein kinase B, J. Biol. Chem., 272, 31515, 10.1074/jbc.272.50.31515 · DOI · Paper page
- Borkhardt, 1997, Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23), Oncogene, 14, 195, 10.1038/sj.onc.1200814 · DOI
- Cardone, 1998, Regulation of cell death protease caspase-9 by phosphorylation, Science, 282, 1318, 10.1126/science.282.5392.1318 · DOI · Paper page
- Cichy, 1998, Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence, J. Biol. Chem., 273, 6482, 10.1074/jbc.273.11.6482 · DOI
- Datta, 1998, Molecular mechanisms of neuronal survival and apoptosis, Horm. Signaling, 1, 257, 10.1016/B978-012312411-1/50010-X · DOI
- Datta, 1997, Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery, Cell, 91, 231, 10.1016/S0092-8674(00)80405-5 · DOI · Paper page
- del Peso, 1997, Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt, Science, 278, 687, 10.1126/science.278.5338.687 · DOI · Paper page
- Downward, 1998, Mechanisms and consequences of activation of protein kinase B/Akt, Curr. Opin. Cell Biol., 10, 262, 10.1016/S0955-0674(98)80149-X · DOI
- Dudek, 1997, Regulation of neuronal survival by the serine-threonine protein kinase Akt, Science, 275, 661, 10.1126/science.275.5300.661 · DOI · Paper page
- Faris, 1998, The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression, J. Immunol., 160, 134, 10.4049/jimmunol.160.1.134 · DOI
- Friesen, 1996, Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells, Nat. Med., 2, 574, 10.1038/nm0596-574 · DOI
- Fruman, 1998, Phosphoinositide kinases, Annu. Rev. Biochem., 67, 481, 10.1146/annurev.biochem.67.1.481 · DOI
- Galili, 1993, Fusion of a forkhead domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma, Nat. Genet., 5, 230, 10.1038/ng1193-230 · DOI
- Hillion, 1997, AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily, Blood, 90, 3714, 10.1182/blood.V90.9.3714 · DOI
- Holtz-Heppelmann, 1998, Transcriptional regulation of the human FasL promoter-enhancer region, J. Biol. Chem., 273, 4416, 10.1074/jbc.273.8.4416 · DOI
- Jacobson, 1997, Programmed cell death in animal development, Cell, 88, 347, 10.1016/S0092-8674(00)81873-5 · DOI
- Kauffmann-Zeh, 1997, Suppression of the c-Myc-induced apoptosis by Ras signaling through PI(3)K and PKB, Nature, 385, 544, 10.1038/385544a0 · DOI
- Kaufmann, 1995, DNA recognition site analysis of Xenopus winged helix proteins, J. Mol. Biol., 248, 239, 10.1016/S0022-2836(95)80047-6 · DOI
- Kennedy, 1997, The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal, Genes Dev., 11, 701, 10.1101/gad.11.6.701 · DOI
- Khanna, 1993, Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells, Oncogene, 8, 3307
- Latinis, 1997, Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells, J. Biol. Chem., 272, 31427, 10.1074/jbc.272.50.31427 · DOI
- Le-Niculescu, 1999, Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death, Mol. Cell Biol., 19, 751, 10.1128/MCB.19.1.751 · DOI
- Liao, 1998, Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene, J. Biol. Chem., 273, 27320, 10.1074/jbc.273.42.27320 · DOI
- Lin, 1997, daf-16, Science, 278, 1319, 10.1126/science.278.5341.1319 · DOI
- Mittelstadt, 1998, Cyclosporin A-sensitive transcription factor Egr-3 regulates Fas ligand expression, Mol. Cell Biol., 18, 3744, 10.1128/MCB.18.7.3744 · DOI
- Miyashita, 1995, Tumor suppressor p53 is a direct transcriptional activator of the human bax gene, Cell, 80, 293, 10.1016/0092-8674(95)90412-3 · DOI · Paper page
- Nagata, 1997, Apoptosis by death factor, Cell, 88, 355, 10.1016/S0092-8674(00)81874-7 · DOI
- O’Brien, 1995, Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes, Mol. Cell Biol., 15, 1747, 10.1128/MCB.15.3.1747 · DOI
- Ogg, 1997, The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans, Nature, 389, 994, 10.1038/40194 · DOI
- Pagès, 1994, Constitutive mutant and putative regulatory serine phosphorylation site of mammalian MAP kinase kinase (MEK1), EMBO J., 13, 3003, 10.1002/j.1460-2075.1994.tb06599.x · DOI
- Paradis, 1998, Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor, Genes Dev., 12, 2488, 10.1101/gad.12.16.2488 · DOI
- Pierrou, 1994, Cloning and characterization of seven human forkhead proteins, EMBO J., 13, 5002, 10.1002/j.1460-2075.1994.tb06827.x · DOI
- Sakamaki, 1998, Molecular cloning and characterization of mouse caspase-8, Eur. J. Biochem., 253, 399, 10.1046/j.1432-1327.1998.2530399.x · DOI
- Songyang, 1997, Interleukin 3-dependent survival by the Akt protein kinase, Proc. Natl. Acad. Sci. USA, 94, 11345, 10.1073/pnas.94.21.11345 · DOI
- Steller, 1995, Mechanisms and genes of cellular suicide, Science, 267, 1445, 10.1126/science.7878463 · DOI
- Sung, 1991, Tumor necrosis factor-alpha mRNA accumulation in human myelomonocytic cell lines. Role of transcriptional regulation by DNA sequence motifs and mRNA stabilization, J. Immunol., 147, 2047, 10.4049/jimmunol.147.6.2047 · DOI
- Yaffe, 1997, The structural basis for 14-3-3:phosphopeptide binding specificity, Cell, 91, 961, 10.1016/S0092-8674(00)80487-0 · DOI
- Yano, 1998, Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway, Nature, 396, 584, 10.1038/25147 · DOI
Cited by
Sorted by citations
Items 101–184 of 184
Transcriptional effects of chronic Akt activation in the heart
Cook, S. A., Matsui, T., Li, L., & Rosenzweig, A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201462200 · Cited by 199
Musclin is an activity-stimulated myokine that enhances physical endurance
Subbotina, E., Sierra, A., Zhu, Z., Gao, Z., Koganti, S. R. K., Reyes, S., Stepniak, E., Walsh, S. A., Acevedo, M. R., Perez-Terzic, C. M., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1514250112 · Cited by 198
Characterization of the direct targets of FOXO transcription factors throughout evolution
Webb, A. E., Kundaje, A., & Brunet, A. (2016) · Aging Cell · doi:10.1111/acel.12479 · Cited by 182
Self-citationWang, C.-Y., Kim, H.-H., Hiroi, Y., Sawada, N., Salomone, S., Benjamin, L. E., Walsh, K., Moskowitz, M. A., & Liao, J. K. (2009) · Science Signaling · doi:10.1126/scisignal.2000143 · Cited by 177
The FoxO transcription factors and metabolic regulation
Nakae, J., Oki, M., & Cao, Y. (2008) · FEBS Letters · doi:10.1016/j.febslet.2007.11.025 · Cited by 176
Eat to reproduce: a key role for the insulin signaling pathway in adult insects
Badisco, L., Van Wielendaele, P., & Vanden Broeck, J. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00202 · Cited by 173
Wang, L., Zhou, K., Fu, Z., Yu, D., Huang, H., Zang, X., & Mo, X. (2017) · Journal of Molecular Neuroscience · doi:10.1007/s12031-016-0872-y · Cited by 172
Yue, T.-L., Bao, W., Gu, J.-L., Cui, J., Tao, L., Ma, X.-L., Ohlstein, E. H., & Jucker, B. M. (2005) · Diabetes · doi:10.2337/diabetes.54.2.554 · Cited by 170
Sishi, B., Loos, B., Ellis, B., Smith, W., du Toit, E. F., & Engelbrecht, A.-M. (2011) · Experimental Physiology · doi:10.1113/expphysiol.2010.054189 · Cited by 162
Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Volpi, E., & Rasmussen, B. B. (2013) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gls209 · Cited by 165
FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis
Webb, A. E., Pollina, E. A., Vierbuchen, T., Urbán, N., Ucar, D., Leeman, D. S., Martynoga, B., Sewak, M., Rando, T. A., Guillemot, F., et al. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.06.035 · Cited by 164
Self-citationChen, M. J., Nguyen, T. V., Pike, C. J., & Russo-Neustadt, A. A. (2007) · Cellular Signalling · doi:10.1016/j.cellsig.2006.05.028 · Cited by 158
Senescent fibroblasts resist apoptosis by downregulating caspase-3.
Marcotte, R., Lacelle, C., & Wang, E. (2004) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2004.07.007 · Cited by 159
Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol
Xia, N., Strand, S., Schlufter, F., Siuda, D., Reifenberg, G., Kleinert, H., Förstermann, U., & Li, H. (2013) · Nitric Oxide · doi:10.1016/j.niox.2013.04.001 · Cited by 157
The cunning little vixen: Foxo and the cycle of life and death
Hedrick, S. M. (2009) · Nature Immunology · doi:10.1038/ni.1784 · Cited by 157
The emerging role of FOXO transcription factors in pancreatic β cells
Glauser, D. A., & Schlegel, W. (2007) · Journal of Endocrinology · doi:10.1677/joe-06-0191 · Cited by 153
MicroRNA 33 Regulates Glucose Metabolism
Ramírez, C. M., Goedeke, L., Rotllan, N., Yoon, J.-H., Cirera-Salinas, D., Mattison, J. A., Suárez, Y., de Cabo, R., Gorospe, M., & Fernández-Hernando, C. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.00016-13 · Cited by 154
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs
Bowman, C. J., Ayer, D. E., & Dynlacht, B. D. (2014) · Nature Cell Biology · doi:10.1038/ncb3062 · Cited by 153
Prostaglandin E 2 induces fibroblast apoptosis by modulating multiple survival pathways
Huang, S. K., White, E. S., Wettlaufer, S. H., Grifka, H., Hogaboam, C. M., Thannickal, V. J., Horowitz, J. C., & Peters-Golden, M. (2009) · The FASEB Journal · doi:10.1096/fj.08-128801 · Cited by 147
Klempner, S. J., Myers, A. P., & Cantley, L. C. (2013) · Cancer Discovery · doi:10.1158/2159-8290.cd-13-0063 · Cited by 148
FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway
Li, W., Du, M., Wang, Q., Ma, X., Wu, L., Guo, F., Ji, H., Huang, F., & Qin, G. (2017) · Endocrinology · doi:10.1210/en.2016-1970 · Cited by 146
Calcium signaling alterations, oxidative stress, and autophagy in aging
Ureshino, R. P., Rocha, K. K., Lopes, G. S., Bincoletto, C., & Smaili, S. S. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2013.5777 · Cited by 143
Wang, H., Wang, M., Chen, J., Tang, Y., Dou, J., Yu, J., Xi, T., & Zhou, C. (2011) · International Immunopharmacology · doi:10.1016/j.intimp.2011.06.006 · Cited by 146
FOXO3A regulates peroxiredoxin III expression in human cardiac fibroblasts
Chiribau, C. B., Cheng, L., Cucoranu, I. C., Yu, Y.-S., Clempus, R. E., & Sorescu, D. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m710610200 · Cited by 140
Wang, L., Wang, J., Blaser, B. W., Duchemin, A.-M., Kusewitt, D. F., Liu, T., Caligiuri, M. A., & Briesewitz, R. (2007) · Blood · doi:10.1182/blood-2007-02-071266 · Cited by 134
Jang, S.-W., Yang, S.-J., Srinivasan, S., & Ye, K. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704542200 · Cited by 133
Choi, S., Jeong, H.-J., Kim, H., Choi, D., Cho, S.-C., Seong, J. K., Koo, S.-H., & Kang, J.-S. (2019) · Autophagy · doi:10.1080/15548627.2019.1569931 · Cited by 132
Forkhead Box O as a Sensor, Mediator, and Regulator of Redox Signaling
de Keizer, P. L. J., Burgering, B. M. T., & Dansen, T. B. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3403 · Cited by 131
FoxO1 integrates insulin signaling to VLDL production.
Kamagate, A., & Dong, H. H. (2008) · Cell Cycle · doi:10.4161/cc.7.20.6882 · Cited by 127
Chakrabarty, A., Bhola, N. E., Sutton, C., Ghosh, R., Kuba, M. G., Dave, B., Chang, J. C., & Arteaga, C. L. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-2440 · Cited by 130
Modulation of Phosphoprotein Activity by Phosphorylation Targeting Chimeras (PhosTACs)
Chen, P.-H., Hu, Z., An, E., Okeke, I., Zheng, S., Luo, X., Gong, A., Jaime-Figueroa, S., & Crews, C. M. (2021) · ACS Chemical Biology · doi:10.1021/acschembio.1c00693 · Cited by 130
Chen, M. J., & Russo‐Neustadt, A. A. (2009) · Hippocampus · doi:10.1002/hipo.20579 · Cited by 129
HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy
Beharry, A. W., Sandesara, P. B., Roberts, B. M., Ferreira, L. F., Senf, S. M., & Judge, A. R. (2014) · Journal of Cell Science · doi:10.1242/jcs.136390 · Cited by 128
Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3
LeBron, C., Chen, L., Gilkes, D. M., & Chen, J. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601032 · Cited by 122
Bedogni, B., Pani, G., Colavitti, R., Riccio, A., Borrello, S., Murphy, M., Smith, R., Eboli, M. L., & Galeotti, T. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m301089200 · Cited by 124
Role of PI3K in the generation and survival of B cells
Werner, M., Hobeika, E., & Jumaa, H. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00934.x · Cited by 122
Shen, M., Liu, Z., Li, B., Teng, Y., Zhang, J., Tang, Y., Sun, S.-C., & Liu, H. (2014) · Cell Death & Disease · doi:10.1038/cddis.2014.400 · Cited by 123
Molecular mechanisms of brain-derived neurotrophic factor in neuro-protection: Recent developments
Zhao, H., Alam, A., San, C.-Y., Eguchi, S., Chen, Q., Lian, Q., & Ma, D. (2017) · Brain Research · doi:10.1016/j.brainres.2017.03.029 · Cited by 122
Kruse, T., Gnosa, S. P., Nasa, I., Garvanska, D. H., Hein, J. B., Nguyen, H., Samsøe‐Petersen, J., Lopez‐Mendez, B., Hertz, E. P. T., Schwarz, J., et al. (2020) · The EMBO Journal · doi:10.15252/embj.2019103695 · Cited by 97
Posttranslational modifications control FoxO3 activity during denervation
Bertaggia, E., Coletto, L., & Sandri, M. (2012) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00142.2011 · Cited by 114
Lee, H.-Y., Chung, J.-W., Youn, S.-W., Kim, J.-Y., Park, K.-W., Koo, B.-K., Oh, B.-H., Park, Y.-B., Chaqour, B., Walsh, K., et al. (2007) · Circulation Research · doi:10.1161/01.res.0000257945.97958.77 · Cited by 107
Powerful signals for weak muscles
Saini, A., Faulkner, S., Al-Shanti, N., & Stewart, C. (2009) · Ageing Research Reviews · doi:10.1016/j.arr.2009.02.001 · Cited by 109
FoxO3 activation in hypoxic tubules prevents chronic kidney disease
Li, L., Kang, H., Zhang, Q., D’Agati, V. D., Al-Awqati, Q., & Lin, F. (2019) · Journal of Clinical Investigation · doi:10.1172/jci122256 · Cited by 105
Pengetnze, Y., Steed, M., Roby, K. F., Terranova, P. F., & Taylor, C. C. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.08.012 · Cited by 107
Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13
Wynes, M. W., & Riches, D. W. H. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.7.3550 · Cited by 105
Rhee, S. H., Kim, H., Moyer, M. P., & Pothoulakis, C. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m513861200 · Cited by 103
Och, A., Och, M., Nowak, R., Podgórska, D., & Podgórski, R. (2022) · Molecules · doi:10.3390/molecules27041351 · Cited by 104
Tseng, Y.-H., Ueki, K., Kriauciunas, K. M., & Kahn, C. R. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202932200 · Cited by 96
de Keizer, P. L. J., Packer, L. M., Szypowska, A. A., Riedl-Polderman, P. E., van den Broek, N. J. F., de Bruin, A., Dansen, T. B., Marais, R., Brenkman, A. B., & Burgering, B. M. T. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-1563 · Cited by 94
Cattaneo, A., Cattane, N., Malpighi, C., Czamara, D., Suarez, A., Mariani, N., Kajantie, E., Luoni, A., Eriksson, J. G., Lahti, J., et al. (2018) · Molecular Psychiatry · doi:10.1038/s41380-017-0002-4 · Cited by 86
Crosstalk between the Rb pathway and AKT signaling forms a quiescence-senescence switch.
Imai, Y., Takahashi, A., Hanyu, A., Hori, S., Sato, S., Naka, K., Hirao, A., Ohtani, N., & Hara, E. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.006 · Cited by 84
Maki, T., Yamamoto, D., Nakanishi, S., Iida, K., Iguchi, G., Takahashi, Y., Kaji, H., Chihara, K., & Okimura, Y. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.07.005 · Cited by 85
Yuan, Z., Kim, D., Shu, S., Wu, J., Guo, J., Xiao, L., Kaneko, S., Coppola, D., & Cheng, J. Q. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.059675 · Cited by 78
RetractedŚmieszek, A., Stręk, Z., Kornicka, K., Grzesiak, J., Weiss, C., & Marycz, K. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18040872 · Cited by 77
Role of the Nrf2-heme oxygenase-1 pathway in silver nanoparticle-mediated cytotoxicity
Kang, S. J., Ryoo, I.-G., Lee, Y. J., & Kwak, M.-K. (2012) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.10.011 · Cited by 76
Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells
Hung, Y. P., Teragawa, C., Kosaisawe, N., Gillies, T. E., Pargett, M., Minguet, M., Distor, K., Rocha-Gregg, B. L., Coloff, J. L., Keibler, M. A., et al. (2017) · eLife · doi:10.7554/elife.27293 · Cited by 74
Serotonin and neuronal growth factors—a convergence of signaling pathways
Cowen, D. S. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04420.x · Cited by 72
TF-DUBTACs Stabilize Tumor Suppressor Transcription Factors
Liu, J., Yu, X., Chen, H., Kaniskan, H. Ü., Xie, L., Chen, X., Jin, J., & Wei, W. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c04824 · Cited by 73
Zhang, W., Konopleva, M., Burks, J. K., Dywer, K. C., Schober, W. D., Yang, J.-Y., McQueen, T. J., Hung, M.-C., & Andreeff, M. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-0878 · Cited by 70
Signaling Pathway Mediating Myeloma Cell Growth and Survival
Hideshima, T., & Anderson, K. C. (2021) · Cancers · doi:10.3390/cancers13020216 · Cited by 70
Urolithin B, a Newly Identified Regulator of Skeletal Muscle Mass
Rodriguez, J., Pierre, N., Naslain, D., Bontemps, F., Ferreira, D., Priem, F., Deldicque, L., & Francaux, M. (2017) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.12190 · Cited by 70
Re Cecconi, A. D., Forti, M., Chiappa, M., Zhu, Z., Zingman, L. V., Cervo, L., Beltrame, L., Marchini, S., & Piccirillo, R. (2019) · Cancers · doi:10.3390/cancers11101541 · Cited by 66
Validation of differentially expressed brain‐enriched microRNAs in the plasma of PD patients
Ravanidis, S., Bougea, A., Papagiannakis, N., Koros, C., Simitsi, A. M., Pachi, I., Breza, M., Stefanis, L., & Doxakis, E. (2020) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51146 · Cited by 63
Rieske, P., & Pongubala, J. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m007482200 · Cited by 54
Pöllänen, E., Ronkainen, P. H. A., Horttanainen, M., Takala, T., Puolakka, J., Suominen, H., Sipilä, S., & Kovanen, V. (2010) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2010.07.003 · Cited by 54
Charidemou, E., Ashmore, T., Li, X., McNally, B. D., West, J. A., Liggi, S., Harvey, M., Orford, E., & Griffin, J. L. (2019) · JCI Insight · doi:10.1172/jci.insight.124819 · Cited by 52
Insulin Regulation of Hepatic Lipid Homeostasis
Uehara, K., Santoleri, D., Whitlock, A. E. G., & Titchenell, P. M. (2023) · Comprehensive Physiology · doi:10.1002/cphy.c220015 · Cited by 49
Akt phosphorylates and suppresses the transactivation of retinoic acid receptor α
Srinivas, H., Xia, D., Moore, N. L., Uray, I. P., Kim, H., Ma, L., Weigel, N. L., Brown, P. H., & Kurie, J. M. (2006) · Biochemical Journal · doi:10.1042/bj20051794 · Cited by 49
Iser, W. B., Gami, M. S., & Wolkow, C. A. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2006.04.467 · Cited by 48
Xia, Y., Qadota, H., Wang, Z.-H., Liu, P., Liu, X., Ye, K. X., Matheny, C. J., Berglund, K., Yu, S. P., Drake, D., et al. (2022) · Science Advances · doi:10.1126/sciadv.abj8658 · Cited by 46
Cavasin, M. A. (2006) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200606050-00003 · Cited by 46
Foxo3a is essential for maintenance of the hematopoietic stem cell pool.
Miyamoto, K., Araki, K. Y., Naka, K., Arai, F., Takubo, K., Yamazaki, S., Matsuoka, S., Miyamoto, T., Ito, K., Ohmura, M., et al. (2007) · Cell stem cell · doi:10.1016/j.stem.2007.02.001 · Cited by 41
Lee, S.-J., Bae, J. H., Lee, H., Lee, H., Park, J., Kang, J.-S., & Bae, G.-U. (2019) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.112054 · Cited by 38
Lu, L., Wang, D.-T., Shi, Y., Yin, Y., Wei, L.-B., Zou, Y.-C., Huang, B., Zhao, Y., Wang, M., Wan, H., et al. (2013) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2013.06.027 · Cited by 33
Liver-specific deletion of Ppp2cα enhances glucose metabolism and insulin sensitivity
Xian, L., Hou, S., Huang, Z., Tang, A., Shi, P., Wang, Q., Song, A., Jiang, S., Lin, Z., Guo, S., et al. (2015) · Aging · doi:10.18632/aging.100725 · Cited by 31
A Low-Testosterone State Associated with Endometrioma Leads to the Apoptosis of Granulosa Cells
Ono, Y. J., Tanabe, A., Nakamura, Y., Yamamoto, H., Hayashi, A., Tanaka, T., Sasaki, H., Hayashi, M., Terai, Y., & Ohmichi, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115618 · Cited by 32
Molecular Effects of Genistein on Male Urethral Development
Ross, A. E., Marchionni, L., Phillips, T. M., Miller, R. M., Hurley, P. J., Simons, B. W., Salmasi, A. H., Schaeffer, A. J., Gearhart, J. P., & Schaeffer, E. M. (2011) · Journal of Urology · doi:10.1016/j.juro.2010.12.095 · Cited by 29
Molecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response
Ruperti, F., Becher, I., Stokkermans, A., Wang, L., Marschlich, N., Potel, C., Maus, E., Stein, F., Drotleff, B., Schippers, K. J., et al. (2024) · Current Biology · doi:10.1016/j.cub.2023.12.021 · Cited by 23
Zhang, H., Pang, X., Yu, H., & Zhou, H. (2022) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.22939 · Cited by 18
EXPRESSION OF CONCERN: Mitophagy protects against statin‐mediated skeletal muscle toxicity
Ramesh, I., Campos, J. C., Lee, P., Song, Y., Hernandez, G., Sin, J., Tucker, K. C., Saadaeijahromi, H., Gurney, M., Ferreira, J. C. B., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900807rr · Cited by 17
Physiological and pathophysiological actions of insulin in the liver
Kubota, N., Kubota, T., & Kadowaki, T. (2025) · Endocrine Journal · doi:10.1507/endocrj.ej24-0192 · Cited by 19
OKAMOTO, T., & MACHIDA, S. (2017) · Biomedical Research · doi:10.2220/biomedres.38.331 · Cited by 16
Querfurth, H., Marshall, J., Parang, K., Rioult-Pedotti, M. S., Tiwari, R., Kwon, B., Reisinger, S., & Lee, H.-K. (2022) · PLOS ONE · doi:10.1371/journal.pone.0261696 · Cited by 9
Miyatake, S., Hino, K., Natsui, Y., Ebisu, G., & Fujita, S. (2020) · Nutrients · doi:10.3390/nu12092729 · Cited by 7
Metadata
- Authors
- Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., & Greenberg, M. E.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1999-03
- Volume
- 96
- Issue
- 6
- Pages
- 857-868
- ISSN
- 0092-8674
- Cited by
- 5,594
- References
- 3
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review