Integration of Long-Term-Memory-Related Synaptic Plasticity Involves Bidirectional Regulation of Gene Expression and Chromatin Structure

The Integrative Action of the Nervous System.

Sherrington, C. (1907) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-190734120-00021 · Cited by 4,136 · see citing works

The molecular biology of memory storage: a dialogue between genes and synapses

Kandel, E. R. (2001) · Science · doi:10.1126/science.1067020 · Cited by 3,917 · see citing works

Phosphorylated CREB binds specifically to the nuclear protein CBP

Chrivia, J. C., Kwok, R. P. S., Lamb, N., Hagiwara, M., Montminy, M. R., & Goodman, R. H. (1993) · Nature · doi:10.1038/365855a0 · Cited by 2,052 · see citing works

CBP/p300 in cell growth, transformation, and development

Goodman, R. H., & Smolik, S. (2000) · Genes & Development · doi:10.1101/gad.14.13.1553 · Cited by 1,778 · see citing works

Protein synthesis and memory: A review.

Davis, H. P., & Squire, L. R. (1984) · Psychological Bulletin · doi:10.1037/0033-2909.96.3.518 · Cited by 1,505 · see citing works

The Integrative Action of the Nervous System.

Freeman, F. N., & SHERRINGTON, S. C. (1907) · The Journal of Philosophy Psychology and Scientific Methods · doi:10.2307/2010953 · Cited by 907 · see citing works

A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in <i>Aplysia</i>

Montarolo, P. G., Goelet, P., Castellucci, V. F., Morgan, J., Kandel, E. R., & Schacher, S. (1986) · Science · doi:10.1126/science.3775383 · Cited by 769 · see citing works

Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage.

Martin, K. C., Casadio, A., Zhu, H.-X., Yaping, E., Rose, J. C., Chen, M. C., Bailey, C. H., & Kandel, E. R. (1997) · Cell · doi:10.1016/s0092-8674(00)80484-5 · Cited by 752 · see citing works

In Vivo Cross-Linking and Immunoprecipitation for Studying Dynamic Protein:DNA Associations in a Chromatin Environment

Kuo, M., & Allis, C. D. (1999) · Methods · doi:10.1006/meth.1999.0879 · Cited by 601 · see citing works

Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change

Bartsch, D., Ghirardi, M., Skehel, P. A., Karl, K. A., Herder, S. P., Chen, M., Bailey, C. H., & Kandel, E. R. (1995) · Cell · doi:10.1016/0092-8674(95)90213-9 · Cited by 572 · see citing works

MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia

Martin, K. C., Michael, D., Rose, J. C., Barad, M., Casadio, A., Zhu, H., & Kandel, E. R. (1997) · Neuron · doi:10.1016/s0896-6273(00)80330-x · Cited by 545 · see citing works

C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia

Alberini, C. M., Ghirardl, M., Metz, R., & Kandel, E. R. (1994) · Cell · doi:10.1016/0092-8674(94)90386-7 · Cited by 523 · see citing works

Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation

Orlando, V. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01535-2 · Cited by 506 · see citing works

A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis

Casadio, A., Martin, K. C., Giustetto, M., Zhu, H., Chen, M., Bartsch, D., Bailey, C. H., & Kandel, E. R. (1999) · Cell · doi:10.1016/s0092-8674(00)81653-0 · Cited by 503 · see citing works

Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin

Furumai, R., Komatsu, Y., Nishino, N., Khochbin, S., Yoshida, M., & Horinouchi, S. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.1.87 · Cited by 412 · see citing works

Conjunction dysfunction: CBP/p300 in human disease

Giles, R. H., Peters, D. J. M., & Breuning, M. H. (1998) · Trends in Genetics · doi:10.1016/s0168-9525(98)01438-3 · Cited by 400 · see citing works

CREB1 Encodes a Nuclear Activator, a Repressor, and a Cytoplasmic Modulator that Form a Regulatory Unit Critical for Long-Term Facilitation

Bartsch, D., Casadio, A., Karl, K. A., Serodio, P., & Kandel, E. R. (1998) · Cell · doi:10.1016/s0092-8674(00)81752-3 · Cited by 373 · see citing works

Neurite regeneration by Aplysia neurons in dissociated cell culture: modulation by Aplysia hemolymph and the presence of the initial axonal segment

Schacher, S., & Proshansky, E. (1983) · Journal of Neuroscience · doi:10.1523/jneurosci.03-12-02403.1983 · Cited by 279 · see citing works

Phosphorylation by p44 MAP Kinase/ERK1 Stimulates CBP Histone Acetyl Transferase Activity in Vitro

Ait‐Si‐Ali, S., Carlisi, D., Ramírez-Clavijo, S. R., Upegui-Gonzalez, L.-C., Duquet, A., Robin, P., Rudkin, B. B., Harel‐Bellan, A., & Trouche, D. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1132 · Cited by 125 · see citing works

Long-term heterosynaptic inhibition in Aplysia

Montarolo, P. G., Kandel, E. R., & Schacher, S. (1988) · Nature · doi:10.1038/333171a0 · Cited by 117 · see citing works

Coincident induction of long-term facilitation in Aplysia: cooperativity between cell bodies and remote synapses.

Sherff, C. M., & Carew, T. J. (1999) · Science · doi:10.1126/science.285.5435.1911 · Cited by 85 · see citing works

Overexpression of and RNA Interference with the CCAAT Enhancer-Binding Protein on Long-Term Facilitation ofAplysiaSensory to Motor SynapsesPreprint

Lee, J. A., Kim, H. K., Kim, K., Han, J., Lee, Y., Lim, C., Chang, D., Kubo, T., & Kaang, B. (2001) · Learning & Memory · doi:10.1101/lm.40201 · Cited by 78 · see citing works

Activation and Degradation of the Transcription Factor C/EBP During Long‐Term Facilitation in Aplysia

Yamamoto, N., Hegde, A. N., Chain, D. G., & Schwartz, J. H. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0732415.x · Cited by 64 · see citing works

Stimulus-specific Interaction between Activator-Coactivator Cognates Revealed with a Novel Complex-specific Antiserum

Wagner, B. L., Bauer, A., Schütz, G., & Montminy, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.12.8263 · Cited by 26 · see citing works

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

Tsankova, N. M., Berton, O., Renthal, W., Kumar, A., Neve, R. L., & Nestler, E. J. (2006) · Nature Neuroscience · doi:10.1038/nn1659 · Cited by 1,780 · see citing works

HDAC2 negatively regulates memory formation and synaptic plasticity

Guan, J.-S., Haggarty, S. J., Giacometti, E., Dannenberg, J.-H., Joseph, N., Gao, J., Nieland, T. J. F., Zhou, Y., Wang, X., Mazitschek, R., et al. (2009) · Nature · doi:10.1038/nature07925 · Cited by 1,644 · see citing works

Epigenetic regulation in psychiatric disorders

Tsankova, N., Renthal, W., Kumar, A., & Nestler, E. J. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2132 · Cited by 1,400 · see citing works

Covalent Modification of DNA Regulates Memory Formation

Miller, C. A., & Sweatt, J. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.02.022 · Cited by 1,180 · see citing works

The Molecular and Systems Biology of Memory

Kandel, E. R., Dudai, Y., & Mayford, M. R. (2014) · Cell · doi:10.1016/j.cell.2014.03.001 · Cited by 1,134 · see citing works

Regulation of histone acetylation during memory formation in the hippocampus

Levenson, J. M., O'Riordan, K. J., Brown, K. D., Trinh, M. A., Molfese, D. L., & Sweatt, J. D. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m402229200 · Cited by 1,131 · see citing works

Transcription Factors in Long-Term Memory and Synaptic Plasticity

Alberini, C. M. (2009) · Physiological Reviews · doi:10.1152/physrev.00017.2008 · Cited by 991 · see citing works

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

Kandel, E. R. (2012) · Molecular Brain · doi:10.1186/1756-6606-5-14 · Cited by 904 · see citing works

Chromatin Acetylation, Memory, and LTP Are Impaired in CBP+/− Mice

Alarcón, J. M., Malleret, G., Touzani, K., Vronskaya, S., Ishii, S., Kandel, E. R., & Barco, A. (2004) · Neuron · doi:10.1016/j.neuron.2004.05.021 · Cited by 892 · see citing works

CBP Histone Acetyltransferase Activity Is a Critical Component of Memory Consolidation

Korzus, E., Rosenfeld, M. G., & Mayford, M. (2004) · Neuron · doi:10.1016/j.neuron.2004.06.002 · Cited by 823 · see citing works

Epigenetic Regulation of <i>bdnf</i> Gene Transcription in the Consolidation of Fear Memory

Lubin, F. D., Roth, T. L., & Sweatt, J. D. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1786-08.2008 · Cited by 793 · see citing works

Epigenetic mechanisms in memory formation

Levenson, J. M., & Sweatt, J. D. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1604 · Cited by 767 · see citing works

Chromatin Remodeling Is a Key Mechanism Underlying Cocaine-Induced Plasticity in Striatum

Kumar, A., Choi, K.-H., Renthal, W., Tsankova, N. M., Theobald, D. E. H., Truong, H.-T., Russo, S. J., LaPlant, Q., Sasaki, T. S., Whistler, K. N., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.09.023 · Cited by 764 · see citing works

Histone acetylation: molecular mnemonics on the chromatin

Gräff, J., & Tsai, L.-H. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3427 · Cited by 680 · see citing works

Maternal care as a model for experience-dependent chromatin plasticity?

Meaney, M. J., & Szyf, M. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.07.006 · Cited by 658 · see citing works

The Restless Engram: Consolidations Never End

Dudai, Y. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-062111-150500 · Cited by 644 · see citing works

A Role for Neuronal piRNAs in the Epigenetic Control of Memory-Related Synaptic Plasticity

Rajasethupathy, P., Antonov, I., Sheridan, R., Frey, S., Sander, C., Tuschl, T., & Kandel, E. R. (2012) · Cell · doi:10.1016/j.cell.2012.02.057 · Cited by 566 · see citing works

Histone Methylation Regulates Memory Formation

Gupta, S., Kim, S. Y., Artis, S., Molfese, D. L., Schumacher, A., Sweatt, J. D., Paylor, R. E., & Lubin, F. D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3732-09.2010 · Cited by 562 · see citing works

Epigenetics and the environmental regulation of the genome and its function

Zhang, T.-Y., & Meaney, M. J. (2010) · Annual Review of Psychology · doi:10.1146/annurev.psych.60.110707.163625 · Cited by 565 · see citing works

From neural development to cognition: unexpected roles for chromatin

Ronan, J. L., Wu, W., & Crabtree, G. R. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3413 · Cited by 544 · see citing works

Decoding the Epigenetic Language of Neuronal Plasticity

Borrelli, E., Nestler, E. J., Allis, C. D., & Sassone‐Corsi, P. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.012 · Cited by 529 · see citing works

Epigenetic mechanisms in cognition

Day, J. J., & Sweatt, J. D. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.019 · Cited by 510 · see citing works

Histone Modifications at Gene Promoter Regions in Rat Hippocampus after Acute and Chronic Electroconvulsive Seizures

Tsankova, N. M., Kumar, A., & Nestler, E. J. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.0589-04.2004 · Cited by 447 · see citing works

Class II Histone Deacetylases: from Sequence to Function, Regulation, and Clinical Implication

Yang, X., & Grégoire, S. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.8.2873-2884.2005 · Cited by 419 · see citing works

DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity

Miller, C. A., Campbell, S. L., & Sweatt, J. D. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.07.016 · Cited by 417 · see citing works

Epigenetic mechanisms of chronic pain

Descalzi, G., Ikegami, D., Ushijima, T., Nestler, E. J., Zachariou, V., & Narita, M. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.02.001 · Cited by 390 · see citing works

Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

Singewald, N., Schmuckermair, C., Whittle, N., Holmes, A., & Ressler, K. J. (2015) · Pharmacology &amp; Therapeutics · doi:10.1016/j.pharmthera.2014.12.004 · Cited by 390 · see citing works

Epigenetic regulation of gene expression in physiological and pathological brain processes

Gräff, J., Kim, D., Dobbin, M. M., & Tsai, L.-H. (2011) · Physiological Reviews · doi:10.1152/physrev.00012.2010 · Cited by 373 · see citing works

Epigenetic regulation of memory formation and maintenancePreprint

Zovkic, I. B., Karlsson, M. G., & Sweatt, J. D. (2013) · Learning & Memory · doi:10.1101/lm.026575.112 · Cited by 362 · see citing works

The Regulation of Transcription in Memory Consolidation

Alberini, C. M., & Kandel, E. R. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021741 · Cited by 362 · see citing works

The molecular and cellular biology of enhanced cognition

Lee, Y.-S., & Silva, A. J. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2572 · Cited by 361 · see citing works

Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat

Szyf, M., Weaver, I. C. G., Champagne, F. A., Diorio, J., & Meaney, M. J. (2005) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2005.10.002 · Cited by 348 · see citing works

Neuroplasticity Mediated by Altered Gene Expression

McClung, C. A., & Nestler, E. J. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301544 · Cited by 347 · see citing works

The Role of Histone Acetylation in Memory Formation and Cognitive Impairments

Peixoto, L., & Abel, T. G. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.86 · Cited by 336 · see citing works

ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning

Chwang, W. B., O’Riordan, K. J., Levenson, J. M., & Sweatt, J. D. (2006) · Learning &amp; Memory · doi:10.1101/lm.152906 · Cited by 341 · see citing works

Epigenetic codes in cognition and behaviour

Gräff, J., & Mansuy, I. M. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.01.021 · Cited by 307 · see citing works

The Potential of HDAC Inhibitors as Cognitive Enhancers

Gräff, J., & Tsai, L. (2013) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-011112-140216 · Cited by 297 · see citing works

Brain function and chromatin plasticity

Dulac, C. G. (2010) · Nature · doi:10.1038/nature09231 · Cited by 299 · see citing works

Molecular Mechanism for a Gateway Drug: Epigenetic Changes Initiated by Nicotine Prime Gene Expression by Cocaine

Levine, A., Huang, Y., Drisaldi, B., Griffin, E. A., Pollak, D. D., Xu, S., Yin, D., Schaffran, C., Kandel, D. B., & Kandel, E. R. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3003062 · Cited by 280 · see citing works

The Persistence of Long-Term Memory

Bailey, C. H., Kandel, E. R., & Si, K. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.017 · Cited by 277 · see citing works

Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing

Schor, I. E., Rascovan, N., Pelisch, F., Alló, M., & Kornblihtt, A. R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810666106 · Cited by 270 · see citing works

Epigenetic Regulation of Neural Gene Expression and Neuronal Function

Feng, J., Fouse, S. D., & Fan, G. (2007) · Pediatric Research · doi:10.1203/pdr.0b013e3180457635 · Cited by 263 · see citing works

Cellular basis of memory for addiction

Nestler, E. J. (2013) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2013.15.4/enestler · Cited by 259 · see citing works

CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum

Levine, A. A., Guan, Z., Barco, Á., Xu, S., Kandel, E. R., & Schwartz, J. H. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509735102 · Cited by 249 · see citing works

Lactate mediates the effects of exercise on learning and memory through SIRT1-dependent activation of hippocampal brain-derived neurotrophic factor (BDNF)

El Hayek, L., Khalifeh, M., Zibara, V., Abi Assaad, R., Emmanuel, N., Karnib, N., El-Ghandour, R., Nasrallah, P., Bilen, M., Ibrahim, P., et al. (2019) · The Journal of Neuroscience · doi:10.1523/jneurosci.1661-18.2019 · Cited by 539 · see citing works

Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246 · see citing works

Class IIa histone deacetylases: regulating the regulators

Martin, M., Kettmann, R., & Dequiedt, F. (2007) · Oncogene · doi:10.1038/sj.onc.1210613 · Cited by 243 · see citing works

Epigenetic Programming by Maternal Behavior and Pharmacological Intervention <i>Nature Versus Nurture: Let's Call The Whole Thing Off</i>

Weaver, I. C. G. (2007) · Epigenetics · doi:10.4161/epi.2.1.3881 · Cited by 239 · see citing works

The Nuclear Kinase Mitogen- and Stress-Activated Protein Kinase 1 Regulates Hippocampal Chromatin Remodeling in Memory Formation

Chwang, W. B., Arthur, J. S. C., Schumacher, A., & Sweatt, J. D. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2522-07.2007 · Cited by 239 · see citing works

Beyond transcription factors: The role of chromatin modifying enzymes in regulating transcription required for memoryPreprint

Barrett, R. M., & Wood, M. A. (2008) · Learning & Memory · doi:10.1101/lm.917508 · Cited by 239 · see citing works

Systemic or intrahippocampal delivery of histone deacetylase inhibitors facilitates fear extinction.

Lattal, K. M., Barrett, R. M., & Wood, M. A. (2007) · Behavioral Neuroscience · doi:10.1037/0735-7044.121.5.1125 · Cited by 236 · see citing works

Molecular Mechanisms of Memory Storage inAplysia

Hawkins, R. D., Kandel, E. R., & Bailey, C. H. (2006) · Biological Bulletin · doi:10.2307/4134556 · Cited by 231 · see citing works

Membrane-associated glucocorticoid activity is necessary for modulation of long-term memory via chromatin modification

Roozendaal, B., Hernandez, A., Cabrera, S. M., Hagewoud, R., Malvaez, M., Stefanko, D. P., Haettig, J., & Wood, M. A. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5717-09.2010 · Cited by 233 · see citing works

Epigenetic Mechanisms of Opioid Addiction

Browne, C. J., Godino, A., Salery, M., & Nestler, E. J. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.06.027 · Cited by 227 · see citing works

Chromatin remodeling in neural development and plasticity

Hsieh, J., & Gage, F. H. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.09.002 · Cited by 225 · see citing works

Synapse- and Stimulus-Specific Local Translation During Long-Term Neuronal Plasticity

Wang, D. O., Kim, S. M., Zhao, Y., Hwang, H., Miura, S. K., Sossin, W. S., & Martin, K. C. (2009) · Science · doi:10.1126/science.1173205 · Cited by 226 · see citing works

Common molecular mechanisms in explicit and implicit memory

Barco, Á., Bailey, C. H., & Kandel, E. R. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03870.x · Cited by 217 · see citing works

Epigenetic regulation and chromatin remodeling in learning and memory

Kim, S., & Kaang, B. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2016.140 · Cited by 212 · see citing works

Diet and the epigenetic (re)programming of phenotypic differences in behavior

McGowan, P. O., Meaney, M. J., & Moshe Szyf, A. (2008) · Brain Research · doi:10.1016/j.brainres.2008.07.074 · Cited by 212 · see citing works

Protein Phosphatase 1 Regulates the Histone Code for Long-Term Memory

Koshibu, K., Gräff, J., Beullens, M., Heitz, F. D., Berchtold, D., Russig, H. D., Farinelli, M., Bollen, M., & Mansuy, I. M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3610-09.2009 · Cited by 202 · see citing works

Maternal separation alters drug intake patterns in adulthood in rats

Moffett, M. C., Vicentic, A., Kozel, M. A., Plotsky, P. M., Francis, D. D., & Kuhar, M. J. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.08.003 · Cited by 199 · see citing works

Associative Learning in Invertebrates

Hawkins, R. D., & Byrne, J. H. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021709 · Cited by 199 · see citing works

Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome

Bjornsson, H. T., Benjamin, J. S., Zhang, L., Weissman, J., Gerber, E. E., Chen, Y.-C., Vaurio, R. G., Potter, M. C., Hansen, K. D., & Dietz, H. C. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3009278 · Cited by 194 · see citing works

Histone deacetylases in memory and cognition

Penney, J., & Tsai, L. (2014) · Science Signaling · doi:10.1126/scisignal.aaa0069 · Cited by 192 · see citing works

Metabolic Regulation of Neuronal Plasticity by the Energy Sensor AMPK

Potter, W. B., O’Riordan, K. J., Barnett, D. G. S., Osting, S., Wagoner, M. P., Bürger, C., & Roopra, A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008996 · Cited by 189 · see citing works

Altered gene expression of histone deacetylases in mood disorder patients

Hobara, T., Uchida, S., Otsuki, K., Matsubara, T., Funato, H., Matsuo, K., Suetsugi, M., & Watanabe, Y. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.08.015 · Cited by 185 · see citing works

Epigenetic mechanisms of major depression: Targeting neuronal plasticity

Uchida, S., Yamagata, H., Seki, T., & Watanabe, Y. (2018) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12621 · Cited by 181 · see citing works

Epigenetics and the Biological Basis of Gene × Environment Interactions

Bagot, R. C., & Meaney, M. J. (2010) · Journal of the American Academy of Child &amp; Adolescent Psychiatry · doi:10.1016/j.jaac.2010.06.001 · Cited by 177 · see citing works

The Role of DNA Methylation in the Central Nervous System and Neuropsychiatric Disorders

Feng, J., & Fan, G. (2009) · International review of neurobiology · doi:10.1016/s0074-7742(09)89004-1 · Cited by 178 · see citing works

How the epigenome integrates information and reshapes the synapse

Campbell, R. R., & Wood, M. A. (2019) · Nature reviews. Neuroscience · doi:10.1038/s41583-019-0121-9 · Cited by 175 · see citing works

In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus

Pittenger, C., & Kandel, E. R. (2003) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1247 · Cited by 174 · see citing works

Lysine Acetyltransferases CBP and p300 as Therapeutic Targets in Cognitive and Neurodegenerative Disorders

Valor, L. M., Viosca, J., López‐Atalaya, J. P., & Barco, Á. (2013) · Current Pharmaceutical Design · doi:10.2174/13816128113199990382 · Cited by 168 · see citing works

Modulation of Chromatin Modification Facilitates Extinction of Cocaine-Induced Conditioned Place Preference

Malvaez, M., Sanchis‐Segura, C., Vo, D., Lattal, K. M., & Wood, M. A. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.032 · Cited by 172 · see citing works

A Bioinformatics Analysis of Memory Consolidation Reveals Involvement of the Transcription Factor c-Rel

Levenson, J. M., Choi, S., Lee, S.-Y., Cao, Y. A., Ahn, H. J., Worley, K. C., Pizzi, M., Liou, H.-C., & Sweatt, J. D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5646-03.2004 · Cited by 170 · see citing works

Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression

Méjat, A., Ramond, F., Bassel‐Duby, R., Khochbin, S., Olson, E. N., & Schaeffer, L. (2005) · Nature Neuroscience · doi:10.1038/nn1408 · Cited by 169 · see citing works

Choline deficiency alters global histone methylation and epigenetic marking at the Rel site of the calbindin 1 gene

Mehedint, M. G., Niculescu, M. D., Craciunescu, C. N., & Zeisel, S. H. (2010) · The FASEB Journal · doi:10.1096/fj.09-140145 · Cited by 167 · see citing works

Epigenetic dysregulation in cognitive disorders

Gräff, J., & Mansuy, I. M. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06787.x · Cited by 163 · see citing works

Chapter 33. Neuroscience of Psychotherapy

Vaughan, S., & Ahmed, M. (2022) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9781615375233.gg33 · Cited by 151 · see citing works

Reinstatement of long-term memory following erasure of its behavioral and synaptic expression in Aplysia

Chen, S., Cai, D., Pearce, K. C., Sun, P. Y., Roberts, A. C., & Glanzman, D. L. (2014) · eLife · doi:10.7554/elife.03896 · Cited by 150 · see citing works

Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury

Dash, P. K., Orsi, S. A., & Moore, A. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.06.028 · Cited by 144 · see citing works

Stress risk factors and stress-related pathology: Neuroplasticity, epigenetics and endophenotypes

Radley, J. J., Kabbaj, M., Jacobson, L., Heydendael, W., Yehuda, R., & Herman, J. P. (2011) · Stress · doi:10.3109/10253890.2011.604751 · Cited by 140 · see citing works

Epigenetic Mechanisms and Gene Networks in the Nervous System

Colvis, C. M., Pollock, J. D., Goodman, R. H., Impey, S., Dunn, J. J., Mandel, G., Champagne, F. A., Mayford, M. R., Korzus, E., Kumar, A., et al. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4119-05.2005 · Cited by 139 · see citing works

Epigenetic regulation of nervous system development by DNA methylation and histone deacetylation

MacDonald, J. L., & Roskams, A. J. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.04.002 · Cited by 136 · see citing works

Epigenetic Mechanisms in Memory and Synaptic Function

Sultan, F. A., & Day, J. J. (2011) · Epigenomics · doi:10.2217/epi.11.6 · Cited by 131 · see citing works

DNA methylation and Rett syndrome

Kriaučionis, S., & Bird, A. P. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg286 · Cited by 125 · see citing works

Epigenetics of drug abuse: predisposition or response

Nielsen, D. A., Utrankar, A., Reyes, J. A., Simons, D. D., & Kosten, T. R. (2012) · Pharmacogenomics · doi:10.2217/pgs.12.94 · Cited by 125 · see citing works

Epigenetic Mechanisms in Memory and Cognitive Decline Associated with Aging and Alzheimer’s Disease

Maity, S., Farrell, K., Navabpour, S., Narayanan, S. N., & Jarome, T. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212280 · Cited by 123 · see citing works

HDAC3 and the molecular brake pad hypothesis

McQuown, S. C., & Wood, M. A. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.04.005 · Cited by 122 · see citing works

Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4

Sailaja, B. S., Cohen-Carmon, D., Zimmerman, G., Soreq, H., & Meshorer, E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209990110 · Cited by 121 · see citing works

Histone Deacetylases and Mood Disorders: Epigenetic Programming in Gene‐Environment Interactions

Machado‐Vieira, R., Ibrahim, L. A., & Zarate, C. A. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00203.x · Cited by 119 · see citing works

Tuning acetylation levels with HAT activators: Therapeutic strategy in neurodegenerative diseases

Selvi, B. R., Cassel, J., Kundu, T. K., & Boutillier, A. (2010) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2010.08.012 · Cited by 117 · see citing works

C/EBPβ and C/EBPδ transcription factors: Basic biology and roles in the CNS

Pulido-Salgado, M., Vidal-Taboada, J. M., & Saura, J. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.06.003 · Cited by 116 · see citing works

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation

Cong, S., Pepers, B. A., Evert, B. O., Rubinsztein, D. C., Roos, R. A. C., van Ommen, G. B., & Dorsman, J. C. (2005) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2005.05.003 · Cited by 116 · see citing works

The effects of repeated social defeat on long-term depressive-like behavior and short-term histone modifications in the hippocampus in male Sprague–Dawley rats

Hollis, F., Wang, H., Dietz, D., Gunjan, A., & Kabbaj, M. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1869-9 · Cited by 109 · see citing works

Combinatorial chromatin modifications and memory storage: A code for memory?: Figure 1.Preprint

Wood, M. A., Hawk, J. D., & Abel, T. G. (2006) · Learning & Memory · doi:10.1101/lm.278206 · Cited by 110 · see citing works

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly

Sawamura, N., Ando, T., Maruyama, Y., Fujimuro, M., Mochizuki, H., Honjo, K., Shimoda, M., Toda, H., Sawamura-Yamamoto, T., Makuch, L., et al. (2008) · Molecular Psychiatry · doi:10.1038/mp.2008.101 · Cited by 107 · see citing works

Cellular, molecular, and epigenetic mechanisms in non-associative conditioning: Implications for pain and memory

Rahn, E. J., Karlsson, M. G., & Sweatt, J. D. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.06.008 · Cited by 108 · see citing works

Transcriptional control of cognitive development

Hong, E. J., West, A. E., & Greenberg, M. E. (2005) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2005.01.002 · Cited by 108 · see citing works

Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus

Hollis, F., Duclot, F., Gunjan, A., & Kabbaj, M. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.09.005 · Cited by 107 · see citing works

Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons

Lai, K.-O., Zhao, Y., Ch'ng, T. H., & Martin, K. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803906105 · Cited by 106 · see citing works

Long-term Depression Overcomes Long-term Facilitation

(2002) · Science Signaling · doi:10.1126/scisignal.1602002tw445

Serotonin-Mediated Synapsin Expression Is Necessary for Long-Term Facilitation of theAplysiaSensorimotor Synapse

Hart, A. K., Fioravante, D., Liu, R., Phares, G. A., Cleary, L. J., & Byrne, J. H. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2816-11.2011 · Cited by 36 · see citing works

Serotonin- and training-induced dynamic regulation of CREB2 in <i>Aplysia</i>

Liu, R.-Y., Shah, S., Cleary, L. J., & Byrne, J. H. (2011) · Learning &amp; Memory · doi:10.1101/lm.2112111 · Cited by 24 · see citing works

The Requirement for Enhanced CREB1 Expression in Consolidation of Long-Term Synaptic Facilitation and Long-Term Excitability in Sensory Neurons of<i>Aplysia</i>

Liu, R.-Y., Cleary, L. J., & Byrne, J. H. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5071-10.2011 · Cited by 60 · see citing works

Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change

Bartsch, D., Ghirardi, M., Skehel, P. A., Karl, K. A., Herder, S. P., Chen, M., Bailey, C. H., & Kandel, E. R. (1995) · Cell · doi:10.1016/0092-8674(95)90213-9 · Cited by 572 · see citing works