Acute effects of steroid hormones and neuropeptides on human social-emotional behavior: A review of single administration studies
Abstract
Steroids and peptides mediate a diverse array of animal social behaviors. Human research is restricted by technical-ethical limitations, and models of the neuroendocrine regulation of social-emotional behavior are therefore mainly limited to non-human species, often under the assumption that human social-emotional behavior is emancipated from hormonal control. Development of acute hormone administration procedures in human research, together with the advent of novel non-invasive neuroimaging techniques, have opened up opportunities to systematically study the neuroendocrinology of human social-emotional behavior. Here, we review all placebo-controlled single hormone administration studies addressing human social-emotional behavior, involving the steroids testosterone and estradiol, and the peptides oxytocin and vasopressin. These studies demonstrate substantial hormonal control over human social-emotional behavior and give insights into the underlying neural mechanisms. Finally, we propose a theoretical model that synthesizes detailed knowledge of the neuroendocrinology of social-emotional behavior in animals with the recently gained data from humans described in our review.
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Gonadal steroids and neuropeptides jointly influence bonding by increasing oxytocin-dopamine interactions.
“Similarly, Bos et al. (62) suggest that gonadal steroids and neuropeptides jointly influence bonding by increasing OT-dopamine interactions.”
From Oxytocin administration to parent enhances infant physiological and behavioral readiness for social engagement (2012) · cites this paper as [62]
The amygdala is part of a neural network involved in emotion processing and is strongly connected to the precuneus/PCC, OFC, ACC and brainstem.
“The amygdala is part of a neural network involved in emotion processing and is strongly connected to other brain regions such as the precuneus/posterior cingulate cortex (PCC), the orbitofrontal cortex (OFC), the anterior cingulate (ACC) and the brainstem (Bos et al., 2012;Pessoa, 2008).”
From Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal (2013) · cites this paper as Bos et al., 2012
Cites
Handbook of Affective Sciences
(2002) · doi:10.1093/oso/9780195126013.001.0001 · Cited by 5,104 · see citing works
Baron‐Cohen, S., Wheelwright, S., Hill, J., Raste, Y., & Plumb, I. (2001) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00715 · Cited by 4,555 · see citing works
Baron‐Cohen, S., Wheelwright, S. J., Hill, J., Raste, Y., & Plumb, I. (2001) · PubMed · Cited by 4,313 · see citing works
(1998) · Cited by 4,012 · see citing works
Empathy for Pain Involves the Affective but not Sensory Components of Pain
Singer, T., Seymour, B., O'Doherty, J., Kaube, H., Dolan, R. J., & Frith, C. D. (2004) · Science · doi:10.1126/science.1093535 · Cited by 3,929 · see citing works
Oxytocin increases trust in humans
Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005) · Nature · doi:10.1038/nature03701 · Cited by 3,690 · see citing works
Deciding advantageously before knowing the advantageous strategy
Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1997) · Science · doi:10.1126/science.275.5304.1293 · Cited by 3,547 · see citing works
Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight.
Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A. R., & Updegraff, J. A. (2000) · Psychological Review · doi:10.1037/0033-295x.107.3.411 · Cited by 3,308 · see citing works
The amygdala: vigilance and emotion
Davis, M., & Whalen, P. J. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000812 · Cited by 2,882 · see citing works
The Neural Bases of Cognitive Conflict and Control in Moral Judgment
Greene, J. D., Nystrom, L. E., Engell, A. D., Darley, J. M., & Cohen, J. D. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.027 · Cited by 2,620 · see citing works
Putting the Altruism Back into Altruism: The Evolution of Empathy
de Waal, F. B. M. (2008) · Annual Review of Psychology · doi:10.1146/annurev.psych.59.103006.093625 · Cited by 2,483 · see citing works
Wingfield, J. C., Hegner, R. E., Dufty, & Ball, G. F. (1990) · The American Naturalist · doi:10.1086/285134 · Cited by 2,330 · see citing works
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091 · see citing works
KRINGELBACH, M. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.03.006 · Cited by 1,977 · see citing works
The Social Brain: Neural Basis of Social Knowledge
Adolphs, R. (2009) · Annual Review of Psychology · doi:10.1146/annurev.psych.60.110707.163514 · Cited by 1,827 · see citing works
Unconscious facial reactions to emotional facial expressions
Dimberg, U., Thunberg, M., & Elmehed, K. (2000) · Psychological Science · doi:10.1111/1467-9280.00221 · Cited by 1,788 · see citing works
Mothers and others: the evolutionary origins of mutual understanding
(2010) · Choice Reviews Online · doi:10.5860/choice.47-3250 · Cited by 1,735 · see citing works
Oxytocin, vasopressin, and the neurogenetics of sociality
Donaldson, Z. R., & Young, L. J. (2008) · Science · doi:10.1126/science.1158668 · Cited by 1,645 · see citing works
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., Gruppe, H., Mattay, V. S., Gallhofer, B., & Meyer-Lindenberg, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3984-05.2005 · Cited by 1,639 · see citing works
The polyvagal theory: phylogenetic substrates of a social nervous system.
Porges, S. W. (2001) · International Journal of Psychophysiology · doi:10.1016/s0167-8760(01)00162-3 · Cited by 1,582 · see citing works
Dunbar, R., & Shultz, S. (2007) · Science · doi:10.1126/science.1145463 · Cited by 1,580 · see citing works
The neural correlates of maternal and romantic love
Bartels, A., & Zeki, S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2003.11.003 · Cited by 1,448 · see citing works
Neuroendocrine perspectives on social attachment and love
Sue Carter, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00055-9 · Cited by 1,425 · see citing works
The mirror neuron system and the consequences of its dysfunction
Iacoboni, M., & Dapretto, M. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn2024 · Cited by 1,401 · see citing works
Sniffing neuropeptides: A transnasal approach to the human brain
Born, J., Lange, T., Kern, W., McGregor, G. P., Bickel, U., & Fehm, H. L. (2002) · Nature Neuroscience · doi:10.1038/nn0602-849 · Cited by 1,356 · see citing works
Understanding others' actions and goals by mirror and mentalizing systems: a meta-analysis
Van Overwalle, F., & Baetens, K. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.06.009 · Cited by 1,329 · see citing works
Oxytocin improves “mind-reading” in humans
Domes, G., Heinrichs, M., Michel, A., Berger, C., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.07.015 · Cited by 1,298 · see citing works
Oxytocin shapes the neural circuitry of trust and trust adaptation in humans
Baumgartner, T., Heinrichs, M., Vonlanthen, A., Fischbacher, U., & Fehr, E. (2008) · Neuron · doi:10.1016/j.neuron.2008.04.009 · Cited by 1,258 · see citing works
Testosterone and human aggression: an evaluation of the challenge hypothesis
Archer, J. E. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.12.007 · Cited by 1,250 · see citing works
Affective consciousness: core emotional feelings in animals and humans.
Panksepp, J. (2005) · Consciousness and Cognition · doi:10.1016/j.concog.2004.10.004 · Cited by 1,217 · see citing works
Self-citationGonadal Steroid Induction of Structural Sex Differences in the Central Nervous System
Arnold, A. P., & Gorski, R. A. (1984) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.07.030184.002213 · Cited by 1,198 · see citing works
The neurobiology of attachment
Insel, T. R., & Young, L. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35053579 · Cited by 1,173 · see citing works
The Neuropeptide Oxytocin Regulates Parochial Altruism in Intergroup Conflict Among Humans
De Dreu, C. K. W., Greer, L. L., Handgraaf, M. J. J., Shalvi, S., Van Kleef, G. A., Baas, M., Ten Velden, F. S., Van Dijk, E., & Feith, S. W. W. (2010) · Science · doi:10.1126/science.1189047 · Cited by 1,148 · see citing works
Social intelligence, innovation, and enhanced brain size in primates
Reader, S. M., & Laland, K. N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.062041299 · Cited by 1,126 · see citing works
Good Natured: The Origins of Right and Wrong in Humans and Other Animals
de Waal, F. (1996) · Dominican Scholar (Dominican University of California) · Cited by 1,077 · see citing works
Landgraf, R., & Neumann, I. D. (2004) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2004.05.001 · Cited by 1,059 · see citing works
Insel, T. R. (2010) · Neuron · doi:10.1016/j.neuron.2010.03.005 · Cited by 1,044 · see citing works
Neural mechanisms of aggression
Nelson, R. J., & Trainor, B. C. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2174 · Cited by 1,021 · see citing works
Automatic and intentional brain responses during evaluation of trustworthiness of faces
Winston, J. S., Strange, B. A., O'Doherty, J., & Dolan, R. J. (2002) · Nature Neuroscience · doi:10.1038/nn816 · Cited by 993 · see citing works
The triune brain in evolution: Role in paleocerebral functions
Legg, C. R. (1990) · Biological Psychology · doi:10.1016/0301-0511(90)90083-9 · Cited by 981 · see citing works
Sapolsky, R. M. (1994) · Medical Entomology and Zoology · Cited by 971 · see citing works
Uvnäs-Moberg, K. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00056-0 · Cited by 966 · see citing works
Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders.
Guastella, A. J., Einfeld, S. L., Gray, K. M., Rinehart, N. J., Tonge, B. J., Lambert, T. J., & Hickie, I. B. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.09.020 · Cited by 962 · see citing works
Promoting social behavior with oxytocin in high-functioning autism spectrum disorders.
Andari, E., Duhamel, J.-R., Zalla, T., Herbrecht, E., Leboyer, M., & Sirigu, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910249107 · Cited by 941 · see citing works
(1990) · Medical Entomology and Zoology · Cited by 919 · see citing works
Oxytocin and the Neural Mechanisms Regulating Social Cognition and Affiliative Behavior
Ross, H. E., & Young, L. J. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.004 · Cited by 856 · see citing works
Oxytocin increases generosity in humans
Zak, P. J., Stanton, A. A., & Ahmadi, S. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001128 · Cited by 831 · see citing works
Vasopressin and Oxytocin Excite Distinct Neuronal Populations in the Central Amygdala
Huber, D., Veinante, P., & Stoop, R. (2005) · Science · doi:10.1126/science.1105636 · Cited by 804 · see citing works
Oxytocin increases gaze to the eye region of human faces
Guastella, A. J., Mitchell, P. B., & Dadds, M. R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.026 · Cited by 798 · see citing works
Feldman, R., Weller, A., Zagoory-Sharon, O., & Levine, A. (2007) · Psychological Science · doi:10.1111/j.1467-9280.2007.02010.x · Cited by 787 · see citing works
Ghashghaei, H. T., & Barbas, H. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00446-3 · Cited by 785 · see citing works
Ditzen, B., Schaer, M., Gabriel, B., Bodenmann, G., Ehlert, U., & Heinrichs, M. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.10.011 · Cited by 784 · see citing works
Oxytocin attenuates amygdala responses to emotional faces regardless of valence
Domes, G., Heinrichs, M., Gläscher, J., Büchel, C., Braus, D. F., & Herpertz, S. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.03.025 · Cited by 774 · see citing works
Adult attachment predicts maternal brain and oxytocin response to infant cues.
Strathearn, L., Fonagy, P., Amico, J., & Montague, P. R. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.103 · Cited by 773 · see citing works
Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans
Hurlemann, R., Patin, A., Onur, O. A., Cohen, M. X., Baumgartner, T., Metzler, S., Dziobek, I., Gallinat, J., Wagner, M., Maier, W., et al. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5538-09.2010 · Cited by 771 · see citing works
ÖHman, A. (1986) · Psychophysiology · doi:10.1111/j.1469-8986.1986.tb00608.x · Cited by 738 · see citing works
Oxytocin Increases Retention of Social Cognition in Autism
Hollander, E., Bartz, J., Chaplin, W., Phillips, A., Sumner, J., Soorya, L., Anagnostou, E., & Wasserman, S. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.030 · Cited by 693 · see citing works
In bad taste: evidence for the oral origins of moral disgust
Chapman, H. A., Kim, D. A., Susskind, J. M., & Anderson, A. K. (2009) · Science · doi:10.1126/science.1165565 · Cited by 691 · see citing works
Oxytocin Infusion Reduces Repetitive Behaviors in Adults with Autistic and Asperger's Disorders
Hollander, E., Novotny, S., Hanratty, M., Yaffe, R., DeCaria, C. M., Aronowitz, B. R., & Mosovich, S. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300021 · Cited by 689 · see citing works
Nelson, E. E., & Panksepp, J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00052-3 · Cited by 688 · see citing works
Thornton, J. W. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.091553298 · Cited by 674 · see citing works
Goodson, J. L., & Bass, A. H. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00043-1 · Cited by 632 · see citing works
Neuropeptidergic regulation of affiliative behavior and social bonding in animals
Lim, M. M., & Young, L. J. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2006.06.028 · Cited by 624 · see citing works
Fries, A. B. W., Ziegler, T. E., Kurian, J. R., Jacoris, S., & Pollak, S. D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504767102 · Cited by 570 · see citing works
The Roles of Androgen Receptors and Androgen-Binding Proteins in Nongenomic Androgen Actions
Heinlein, C. A., & Chang, C. (2002) · Molecular Endocrinology · doi:10.1210/me.2002-0070 · Cited by 568 · see citing works
Oxytocin Attenuates Amygdala Reactivity to Fear in Generalized Social Anxiety Disorder
Labuschagne, I., Phan, K. L., Wood, A., Angstadt, M., Chua, P., Heinrichs, M., Stout, J. C., & Nathan, P. J. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.123 · Cited by 549 · see citing works
Intranasal Administration of Oxytocin Increases Envy and Schadenfreude (Gloating)
Shamay-Tsoory, S. G., Fischer, M., Dvash, J., Harari, H., Perach-Bloom, N., & Levkovitz, Y. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.06.009 · Cited by 542 · see citing works
Hormonal correlates of paternal responsiveness in new and expectant fathers
Storey, A. (2000) · Evolution and Human Behavior · doi:10.1016/s1090-5138(99)00042-2 · Cited by 536 · see citing works
Endogenous opioids and social behavior
Panksepp, J., Herman, B. H., Vilberg, T., Bishop, P., & DeEskinazi, F. G. (1980) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(80)90036-6 · Cited by 531 · see citing works
Self-citationEffects of intranasal oxytocin on emotional face processing in women
Domes, G., Lischke, A., Berger, C., Grossmann, A., Hauenstein, K., Heinrichs, M., & Herpertz, S. C. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.06.016 · Cited by 521 · see citing works
Lower CSF oxytocin concentrations in women with a history of childhood abuse
Heim, C., Young, L. J., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.112 · Cited by 518 · see citing works
Vasopressin: Behavioral roles of an “original” neuropeptide
Caldwell, H. K., Lee, H.-J., Macbeth, A. H., & Young, W. S. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.10.007 · Cited by 504 · see citing works
Ferris, C. F., Melloni Jr, R. H., Koppel, G., Perry, K. W., Fuller, R. W., & Delville, Y. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-11-04331.1997 · Cited by 495 · see citing works
Ogawa, S., Eng, V., Taylor, J. A., Lubahn, D. B., Korach, K. S., & Pfaff, D. W. (1998) · Endocrinology · doi:10.1210/endo.139.12.6357 · Cited by 487 · see citing works
Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans
Gamer, M., Zurowski, B., & Büchel, C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000985107 · Cited by 487 · see citing works
Superior Temporal Sulcus—It's My Area: Or Is It?
Hein, G., & Knight, R. T. (2008) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2008.20148 · Cited by 486 · see citing works
Oxytocin, vasopressin, and social recognition in mammals
Bielsky, I. F., & Young, L. J. (2004) · Peptides · doi:10.1016/j.peptides.2004.05.019 · Cited by 460 · see citing works
Engelmann, M., Landgraf, R., & Wotjak, C. T. (2004) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2004.09.001 · Cited by 450 · see citing works
Oxytocin selectively improves empathic accuracy
Bartz, J. A., Zaki, J., Bolger, N., Hollander, E., Ludwig, N. N., Kolevzon, A., & Ochsner, K. N. (2010) · Psychological Science · doi:10.1177/0956797610383439 · Cited by 442 · see citing works
Brain Oxytocin Correlates with Maternal Aggression: link to Anxiety
Bosch, O. J., Meddle, S. L., Beiderbeck, D. I., Douglas, A. J., & Neumann, I. D. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1342-05.2005 · Cited by 439 · see citing works
Sex differences in oxytocin and vasopressin: Implications for autism spectrum disorders?
CARTER, C. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.08.025 · Cited by 432 · see citing works
Prejudice and truth about the effect of testosterone on human bargaining behaviour
Eisenegger, C., Naef, M., Snozzi, R., Heinrichs, M., & Fehr, E. (2009) · Nature · doi:10.1038/nature08711 · Cited by 430 · see citing works
Oxytocin Attenuates Affective Evaluations of Conditioned Faces and Amygdala Activity
Petrovic, P., Kalisch, R., Singer, T., & Dolan, R. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4572-07.2008 · Cited by 424 · see citing works
Androgens, brain, and behavior
Rubinow, D. R., & Schmidt, P. J. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.8.974 · Cited by 417 · see citing works
Cross-cultural Reading the Mind in the Eyes: An fMRI Investigation
Adams, R. B., Rule, N. O., Franklin, R. G., Wang, E. J., Stevenson, M. T., Yoshikawa, S., Nomura, M., Sato, W., Kveraga, K., & Ambady, N. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21187 · Cited by 415 · see citing works
The orbitofrontal-amygdala circuit and self-regulation of social-emotional behavior in autism
Bachevalier, J., & Loveland, K. A. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.07.002 · Cited by 402 · see citing works
Oxytocin Makes a Face in Memory Familiar
Rimmele, U., Hediger, K., Heinrichs, M., & Klaver, P. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4260-08.2009 · Cited by 402 · see citing works
Testosterone and prolactin are associated with emotional responses to infant cries in new fathers
Fleming, A. S., Corter, C., Stallings, J., & Steiner, M. (2002) · Hormones and Behavior · doi:10.1006/hbeh.2002.1840 · Cited by 401 · see citing works
Friend or foe: The effect of implicit trustworthiness judgments in social decision-making
Wout‐Frank, M. V. ‘., & Sanfey, A. G. (2008) · Cognition · doi:10.1016/j.cognition.2008.07.002 · Cited by 400 · see citing works
Is brain estradiol a hormone or a neurotransmitter?
Balthazart, J., & Ball, G. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.03.004 · Cited by 397 · see citing works
Cerebrospinal Fluid Vasopressin Levels
Coccaro, E. F., Kavoussi, R. J., Hauger, R. L., Cooper, T. B., & Ferris, C. F. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.8.708 · Cited by 392 · see citing works
Oxytocin, motherhood and bonding
Kendrick, K. M. (2000) · Experimental Physiology · doi:10.1111/j.1469-445x.2000.tb00014.x · Cited by 378 · see citing works
Waytz, A. G., Nicholas Epley, A., & Cacioppo, J. T. (2010) · Current Directions in Psychological Science · doi:10.1177/0963721409359302 · Cited by 370 · see citing works
Towards a unifying neural theory of social cognition
Keysers, C., & Gazzola, V. (2006) · Progress in Brain Research · doi:10.1016/s0079-6123(06)56021-2 · Cited by 367 · see citing works
Guastella, A. J., Howard, A. L., Dadds, M. R., Mitchell, P., & Carson, D. S. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.01.005 · Cited by 366 · see citing works
Frontal lobe connections of the superior temporal sulcus in the rhesus monkey
Seltzer, B., & Pandya, D. Ν. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902810108 · Cited by 357 · see citing works
Oxytocin enhances the encoding of positive social memories in humans.
Guastella, A. J., Mitchell, P. B., & Mathews, F. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.02.008 · Cited by 352 · see citing works
Handbook of Neurochemistry and Molecular Neurobiology
Lajtha, Á., Galoyan, A. A., & Besedovsky, H. O. (2007) · Springer eBooks · doi:10.1007/978-0-387-30398-7 · Cited by 350 · see citing works
Hermans, E. J., Ramsey, N. F., & van Honk, J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.05.013 · Cited by 339 · see citing works
Self-citationGood natured: The origins of right and wrong in humans and other animals
Corning, P. A. (1996) · Journal of Social and Evolutionary Systems · doi:10.1016/s1061-7361(96)90039-9 · Cited by 338 · see citing works
Neumann, I., Russell, J. A., & Landgraf, R. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90285-n · Cited by 337 · see citing works
Evolutionary Context of Human Development: The Cooperative Breeding Model
Hrdy, S. B. (2007) · Family Relationships · doi:10.1093/acprof:oso/9780195320510.003.0003 · Cited by 333 · see citing works
Declerck, C. H., Boone, C., & Kiyonari, T. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.01.006 · Cited by 331 · see citing works
The Psychobiology of Attachment and Separation
(1985) · Elsevier eBooks · doi:10.1016/b978-0-12-586780-1.x5001-0 · Cited by 323 · see citing works
Oxytocin improves specific recognition of positive facial expressions
Marsh, A. A., Yu, H. H., Pine, D. S., & Blair, R. J. R. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1780-4 · Cited by 321 · see citing works
Theodoridou, A., Rowe, A. C., Penton-Voak, I. S., & Rogers, P. J. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.03.019 · Cited by 318 · see citing works
Sex-specific influences of vasopressin on human social communication
Thompson, R. R., George, K., Walton, J. C., Orr, S. P., & Benson, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600406103 · Cited by 312 · see citing works
Testosterone shifts the balance between sensitivity for punishment and reward in healthy young women
van Honk, J., Schutter, D. J. L. G., Hermans, E. J., Putman, P., Tuiten, A., & Koppeschaar, H. P. F. (2003) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2003.08.007 · Cited by 308 · see citing works
Self-citationForebrain steroid levels fluctuate rapidly during social interactions
Remage‐Healey, L., Maidment, N. T., & Schlinger, B. A. (2008) · Nature Neuroscience · doi:10.1038/nn.2200 · Cited by 302 · see citing works
Minding animals: awareness, emotions, and heart
(2002) · Choice Reviews Online · doi:10.5860/choice.40-1522 · Cited by 296 · see citing works
Time Course of Effects of Testosterone Administration on Sexual Arousal in Women
Tuiten, A., Van Honk, J., Koppeschaar, H., Bernaards, C., Thijssen, J., & Verbaten, R. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.2.149 · Cited by 288 · see citing works
Neural Mechanisms of the Testosterone–Aggression Relation: The Role of Orbitofrontal Cortex
Mehta, P. H., & Beer, J. S. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21389 · Cited by 286 · see citing works
Methods in social neuroscience
Harmon‐Jones, E., & Beer, J. S. (2009) · Cited by 280 · see citing works
Brain vasopressin is an important regulator of maternal behavior independent of dams’ trait anxiety
Bosch, O. J., & Neumann, I. D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807412105 · Cited by 280 · see citing works
Fleming, A. S., Ruble, D., Krieger, H., & Wong, P. Y. (1997) · Hormones and Behavior · doi:10.1006/hbeh.1997.1376 · Cited by 278 · see citing works
Attachment and bonding: A new synthesis.
Carter, C. S., Ahnert, L., Grossmann, K. E., Hrdy, S. B., Lamb, M. E., Porges, S. W., & Sachser, N. (2005) · Cited by 271 · see citing works
Attachment, aggression and affiliation: the role of oxytocin in female social behavior
Campbell, A. (2008) · Biological Psychology · doi:10.1016/j.biopsycho.2007.09.001 · Cited by 269 · see citing works
Testosterone release and social context: When it occurs and why
Gleason, E. D., Fuxjager, M. J., Oyegbile, T. O., & Marler, C. A. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.04.009 · Cited by 268 · see citing works
van Honk, J., Peper, J. S., & Schutter, D. J. L. G. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.003 · Cited by 266 · see citing works
Self-citationNeuropeptides and the evolution of social behavior
Insel, T. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00146-x · Cited by 264 · see citing works
Septal vasopressin modulates social memory in male rats
Dantzer, R., Koob, G. F., Bluthe´, R.-M., & Le Moal, M. (1988) · Brain Research · doi:10.1016/0006-8993(88)90066-2 · Cited by 262 · see citing works
Post-learning intranasal oxytocin modulates human memory for facial identity
Savaskan, E., Ehrhardt, R., Schulz, A., Walter, M., & Schächinger, H. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.12.004 · Cited by 262 · see citing works
Blume, A., Bosch, O. J., Miklos, S., Torner, L., Wales, L., Waldherr, M., & Neumann, I. D. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06184.x · Cited by 255 · see citing works
Singer, T., Snozzi, R., Bird, G., Petrovic, P., Silani, G., Heinrichs, M., & Dolan, R. J. (2008) · Emotion · doi:10.1037/a0014195 · Cited by 248 · see citing works
Testosterone Administration Decreases Generosity in the Ultimatum Game
Zak, P. J., Kurzban, R., Ahmadi, S., Swerdloff, R. S., Park, J., Efremidze, L., Redwine, K. M., Morgan, K., & MATZNER, W. T. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008330 · Cited by 245 · see citing works
Testosterone promotes paternal behaviour in a monogamous mammal via conversion to oestrogen
Trainor, B. C., & Marler, C. A. (2002) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.2001.1954 · Cited by 238 · see citing works
A Single Administration of Testosterone Reduces Fear-Potentiated Startle in Humans
Hermans, E. J., Putman, P., Baas, J. M. P., Koppeschaar, H. P. F., & van Honk, J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.11.015 · Cited by 232 · see citing works
Self-citationWotjak, C. T., Kubota, M., Liebsch, G., Montkowski, A., Holsboer, F., Neumann, I. D., & Landgraf, R. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-23-07725.1996 · Cited by 231 · see citing works
Testosterone administration reduces empathetic behavior: A facial mimicry study
Hermans, E. J., Putman, P., & van Honk, J. (2006) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2006.04.002 · Cited by 231 · see citing works
Self-citationVaginal stimulation: an important determinant of maternal bonding in sheep
Keverne, E. B., Levy, F., Poindron, P., & Lindsay, D. R. (1983) · Science · doi:10.1126/science.6849123 · Cited by 230 · see citing works
Di Simplicio, M., Massey-Chase, R., Cowen, P., & Harmer, C. (2009) · Journal of Psychopharmacology · doi:10.1177/0269881108095705 · Cited by 229 · see citing works
Cornil, C. A., Ball, G. F., & Balthazart, J. (2006) · Brain Research · doi:10.1016/j.brainres.2006.07.098 · Cited by 223 · see citing works
Naber, F., van IJzendoorn, M. H., Deschamps, P., van Engeland, H., & Bakermans-Kranenburg, M. J. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.04.007 · Cited by 222 · see citing works
Neural mechanisms of the testosterone-aggression relation: The role of the orbito-frontal cortex
Mehta, P. H. (2010) · PsycEXTRA Dataset · doi:10.1037/e554362012-158 · Cited by 221 · see citing works
Testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus
Delville, Y., Mansour, K. M., & Ferris, C. F. (1996) · Physiology & Behavior · doi:10.1016/0031-9384(95)02246-5 · Cited by 218 · see citing works
Oxytocin makes people trusting, not gullible
Mikolajczak, M., Gross, J. J., Lane, A., Corneille, O., de Timary, P., & Luminet, O. (2010) · Psychological Science · doi:10.1177/0956797610377343 · Cited by 216 · see citing works
Vasopressin, oxytocin and social behaviour
Keverne, E. B., & Curley, J. P. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.10.006 · Cited by 215 · see citing works
Genes, brains and mammalian social bonds
Curley, J. P., & Keverne, E. B. (2005) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2005.05.018 · Cited by 214 · see citing works
Sensitivity to Intranasal Oxytocin in Adult Men with Early Parental Separation
Meinlschmidt, G., & Heim, C. C. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.007 · Cited by 210 · see citing works
Testosterone decreases trust in socially naïve humans
Bos, P. A., Terburg, D., & van Honk, J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911700107 · Cited by 210 · see citing works
Self-citationHermans, E. J., Bos, P. A., Ossewaarde, L., Ramsey, N. F., Fernández, G., & van Honk, J. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.04.019 · Cited by 208 · see citing works
Self-citationMaternal brain response to own baby‐cry is affected by cesarean section delivery
Swain, J. E., Tasgin, E., Mayes, L. C., Feldman, R., Todd Constable, R., & Leckman, J. F. (2008) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01963.x · Cited by 206 · see citing works
Goodson, J. L., & Kabelik, D. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.05.007 · Cited by 204 · see citing works
Testosterone reduces amygdala–orbitofrontal cortex coupling
van Wingen, G. A., Mattern, C., Verkes, R. J., Buitelaar, J. K., & Fernández, G. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.09.007 · Cited by 203 · see citing works
Amygdala Activation Predicts Gaze toward Fearful Eyes
Gamer, M., & Buchel, C. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1883-09.2009 · Cited by 203 · see citing works
Ebner, K., Bosch, O. J., Krömer, S. A., Singewald, N., & Neumann, I. D. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300607 · Cited by 200 · see citing works
Michels, G., & Hoppe, U. C. (2008) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.08.004 · Cited by 198 · see citing works
Febo, M., Numan, M., & Ferris, C. F. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3604-05.2005 · Cited by 197 · see citing works
Arginine Vasopressin and Oxytocin Modulate Human Social Behavior
Ebstein, R. P., Israel, S., Lerer, E., Uzefovsky, F., Shalev, I., Gritsenko, I., Riebold, M., Salomon, S., & Yirmiya, N. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04541.x · Cited by 194 · see citing works
Anxiety and orienting of gaze to angry and fearful faces
Mogg, K., Garner, M., & Bradley, B. P. (2007) · Biological Psychology · doi:10.1016/j.biopsycho.2007.07.005 · Cited by 192 · see citing works
The effect of intranasal administration of oxytocin on fear recognition
Fischer-Shofty, M., Shamay-Tsoory, S. G., Harari, H., & Levkovitz, Y. (2010) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.09.003 · Cited by 184 · see citing works
The effects of vasopressin on human facial responses related to social communication
Thompson, R. R., Gupta, S., Miller, K., Mills, S. D., & Orr, S. P. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(02)00133-6 · Cited by 184 · see citing works
Veenema, A. H., Beiderbeck, D. I., Lukas, M., & Neumann, I. D. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.03.006 · Cited by 180 · see citing works
van Honk, J., Tuiten, A., Hermans, E. J., Putnam, P., Koppeschaar, H. P. F., Thijssen, J. H. H., Verbaten, R., & van Doornen, L. J. P. (2001) · Behavioral Neuroscience · doi:10.1037/0735-7044.115.1.238 · Cited by 176 · see citing works
Self-citationWindle, R. J., Shanks, N., Lightman, S. L., & Ingram, C. D. (1997) · Endocrinology · doi:10.1210/en.138.7.2829 · Cited by 170 · see citing works
Sex differences in vasopressin and oxytocin innervation of the brain
DEVRIES, G. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00402-0 · Cited by 169 · see citing works
Kendrick, K. M., Keverne, E. B., Chapman, C., & Baldwin, B. A. (1988) · Brain Research · doi:10.1016/0006-8993(88)91447-3 · Cited by 168 · see citing works
The acute effects of intranasal oxytocin administration on endocrine and sexual function in males
Burri, A., Heinrichs, M., Schedlowski, M., & Kruger, T. H. C. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.01.014 · Cited by 168 · see citing works
Brain Opioids and Social Emotions
Panksepp, J., Siviy, S. M., & NORMANSELL, L. A. (1985) · Elsevier eBooks · doi:10.1016/b978-0-12-586780-1.50006-9 · Cited by 165 · see citing works
Self-citationTesticular function, social rank and personality among wild baboons
Sapolsky, R. M. (1991) · Psychoneuroendocrinology · doi:10.1016/0306-4530(91)90015-l · Cited by 164 · see citing works
Androgen-dependent vasopressinergic neurons are involved in social recognition in rats
Bluthe, R.-M., Schoenen, J., & Dantzer, R. (1990) · Brain Research · doi:10.1016/0006-8993(90)90073-k · Cited by 164 · see citing works
Wynne‐Edwards, K. E., & Timonin, M. E. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.03.018 · Cited by 163 · see citing works
Neumann, I. D. (2009) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2009.04.012 · Cited by 162 · see citing works
Exogenous testosterone attenuates the integrated central stress response in healthy young women
Hermans, E. J., Putman, P., Baas, J. M. P., Gecks, N. M., Kenemans, J. L., & van Honk, J. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.08.006 · Cited by 156 · see citing works
Self-citationKendrick, K. M., Keverne, E. B., Hinton, M. R., & Goode, J. A. (1992) · Brain Research · doi:10.1016/0006-8993(92)90631-i · Cited by 150 · see citing works
Pitman, R. K., Orr, S. P., & Lasko, N. B. (1993) · Psychiatry Research · doi:10.1016/0165-1781(93)90035-f · Cited by 150 · see citing works
Oxytocin—its role in male reproduction and new potential therapeutic uses
Thackare, H., Nicholson, H. D., & Whittington, K. (2006) · Human Reproduction Update · doi:10.1093/humupd/dmk002 · Cited by 146 · see citing works
Winslow, J., & Insel, T. (1991) · The Journal of Neuroscience · doi:10.1523/jneurosci.11-07-02032.1991 · Cited by 145 · see citing works
Testosterone Increases Amygdala Reactivity in Middle-Aged Women to a Young Adulthood Level
van Wingen, G. A., Zylicz, S. A., Pieters, S., Mattern, C., Verkes, R. J., Buitelaar, J. K., & Fernández, G. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.2 · Cited by 144 · see citing works
Intranasal oxytocin modulates EEG mu/alpha and beta rhythms during perception of biological motion
Perry, A., Bentin, S., Shalev, I., Israel, S., Uzefovsky, F., Bar-On, D., & Ebstein, R. P. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2010.04.011 · Cited by 143 · see citing works
Testosterone Reduces Conscious Detection of Signals Serving Social Correction
van Honk, J., & Schutter, D. J. L. G. (2007) · Psychological Science · doi:10.1111/j.1467-9280.2007.01955.x · Cited by 142 · see citing works
Self-citationPrimate brain evolution : genetic and functional considerations
(1996) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.1996.0103 · Cited by 137 · see citing works
van Kesteren, R. E., Smit, A. B., Lange, R. D., Kits, K. S., Golen, F. A. V., van der Schors, R. C., de With, N. D., Burke, J. F., & Geraerts, W. P. M. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-05989.1995 · Cited by 136 · see citing works
The neurohypophysial endocrine regulatory cascade: precursors, mediators, receptors, and effectors
Acher, R., & Chauvet, J. (1995) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1995.1009 · Cited by 135 · see citing works
Reduced aggressive behaviour in mice with targeted disruption of the oxytocin gene
DeVries, A. C., Young III, W. S., & Nelson, R. J. (1997) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.1997.t01-1-00589.x · Cited by 134 · see citing works
Vasopressin released within the central amygdala promotes maternal aggression
Bosch, O. J., & Neumann, I. D. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07115.x · Cited by 134 · see citing works
Medial amygdala and aggressive behavior: Interaction between testosterone and vasopressin
Koolhaas, J. M., Brink, T. H. C. V. D., Roozendaal, B., & Boorsma, F. (1990) · Aggressive Behavior · doi:10.1002/1098-2337(1990)16:3/4 · Cited by 134 · see citing works
Pietrowsky, R., Strüben, C., Mölle, M., Fehm, H. L., & Jan Born, A. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00180-8 · Cited by 133 · see citing works
Zink, C. F., Stein, J. L., Kempf, L., Hakimi, S., & Meyer‐Lindenberg, A. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4899-09.2010 · Cited by 131 · see citing works
Intranasal Arginine Vasopressin Enhances the Encoding of Happy and Angry Faces in Humans
Guastella, A. J., Kenyon, A. R., Alvares, G. A., Carson, D. S., & Hickie, I. B. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.03.014 · Cited by 130 · see citing works
Wersinger, S. R., Caldwell, H. K., Christiansen, M., & Young, W. S. (2006) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2006.00294.x · Cited by 130 · see citing works
Mikolajczak, M., Pinon, N., Lane, A., de Timary, P., & Luminet, O. (2010) · Biological Psychology · doi:10.1016/j.biopsycho.2010.05.010 · Cited by 129 · see citing works
Oxytocin-messages via the cerebrospinal fluid: Behavioral effects; a review
Veening, J. G., A, T. R. D. J., & Barendregt, H. P. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.05.004 · Cited by 126 · see citing works
Behavioral endocrinology of mammalian fatherhood
Wynne‐Edwards, K. E., & Wheaton, C. J. (2000) · Trends in Ecology & Evolution · doi:10.1016/s0169-5347(00)01972-8 · Cited by 126 · see citing works
Oxytocin selectively facilitates recognition of positive sex and relationship words.
Unkelbach, C., Guastella, A. J., & Forgas, J. P. (2008) · Psychological Science · doi:10.1111/j.1467-9280.2008.02206.x · Cited by 122 · see citing works
Han, T. M., & De Vries, G. J. (2003) · Journal of Neurobiology · doi:10.1002/neu.10157 · Cited by 116 · see citing works
Decoupling of midfrontal delta–beta oscillations after testosterone administration
Schutter, D. J. L. G., & van Honk, J. (2004) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2003.12.012 · Cited by 116 · see citing works
Self-citationDoes oxytocin influence the early detection of angry and happy faces?
Guastella, A. J., Carson, D. S., Dadds, M. R., Mitchell, P. B., & Cox, R. E. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.09.001 · Cited by 114 · see citing works
Oxytocin and Vasopressin: Genetics and Behavioral Implications
Caldwell, H. K., & Young, W. S. (2006) · Springer eBooks · doi:10.1007/0-387-30395-2_25 · Cited by 113 · see citing works
Oxytocin and vasopressin: genetics and behavioral implications
Caldwell, H. K., & Young, W. S. (2006) · Handbook of Neurochemistry and Molecular Neurobiology · doi:10.1007/978-0-387-30381-9_25 · Cited by 113 · see citing works
Impact of prosocial neuropeptides on human brain function
MEYERLINDENBERG, A. (2008) · Progress in Brain Research · doi:10.1016/s0079-6123(08)00436-6 · Cited by 109 · see citing works
Panksepp, J. (2000) · Consciousness & Emotion · doi:10.1075/ce.1.1.04pan · Cited by 109 · see citing works
Self-citationBiegon, A. R., Kim, S. W., Alexoff, D. L., Jayne, M. C., Carter, P., Hubbard, B., King, P. T., Logan, J., Muench, L., Pareto, D., et al. (2010) · Synapse · doi:10.1002/syn.20791 · Cited by 107 · see citing works
Panksepp, J. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb34359.x · Cited by 106 · see citing works
Self-citationUnmasking feigned sanity: A neurobiological model of emotion processing in primary psychopathy
van Honk, J., & Schutter, D. J. L. G. (2006) · Cognitive Neuropsychiatry · doi:10.1080/13546800500233728 · Cited by 103 · see citing works
Self-citationMolecular evolution of biologically active polypeptides
Acher, R. (1980) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1980.0116 · Cited by 100 · see citing works
Testosterone administration modulates neural responses to crying infants in young females
Bos, P. A., Hermans, E. J., Montoya, E. R., Ramsey, N. F., & van Honk, J. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.09.013 · Cited by 99 · see citing works
Self-citationOxytocin decreases aversion to angry faces in an associative learning task
Evans, S., Shergill, S. S., & Averbeck, B. B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.110 · Cited by 97 · see citing works
Behavioural impact of intraseptally released vasopressin and oxytocin in rats
Englemann, M., Wotjak, C. T., Ebner, K., & Landgraf, R. (2000) · Experimental Physiology · doi:10.1111/j.1469-445x.2000.tb00015.x · Cited by 94 · see citing works
Acute effects of intranasal oxytocin on subjective and behavioral responses to social rejection.
Alvares, G. A., Hickie, I. B., & Guastella, A. J. (2010) · Experimental and Clinical Psychopharmacology · doi:10.1037/a0019719 · Cited by 92 · see citing works
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Understanding adolescence as a period of social–affective engagement and goal flexibility
Crone, E. A., & Dahl, R. E. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3313 · Cited by 2,507 · see citing works
Toward a second-person neuroscience
Schilbach, L., Timmermans, B., Reddy, V., Costall, A., Bente, G., Schlicht, T., & Vogeley, K. (2013) · Behavioral and Brain Sciences · doi:10.1017/s0140525x12000660 · Cited by 1,510 · see citing works
Importance of investing in adolescence from a developmental science perspective
Dahl, R. E., Allen, N. B., Wilbrecht, L., & Suleiman, A. B. (2018) · Nature · doi:10.1038/nature25770 · Cited by 1,196 · see citing works
Oxytocin and social affiliation in humans
Feldman, R. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.01.008 · Cited by 767 · see citing works
Biosocial construction of sex differences and similarities in behavior
Wood, W., & Eagly, A. H. (2012) · Advances in experimental social psychology · doi:10.1016/b978-0-12-394281-4.00002-7 · Cited by 770 · see citing works
The role of testosterone in social interaction
Eisenegger, C., Haushofer, J., & Fehr, E. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.04.008 · Cited by 630 · see citing works
Why Interventions to Influence Adolescent Behavior Often Fail but Could Succeed
Yeager, D. S., Dahl, R. E., & Dweck, C. S. (2018) · Perspectives on Psychological Science · doi:10.1177/1745691617722620 · Cited by 512 · see citing works
De Dreu, C. K. W. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.009 · Cited by 455 · see citing works
Problems with measuring peripheral oxytocin: can the data on oxytocin and human behavior be trusted?
McCullough, M. E., Churchland, P. S., & Mendez, A. J. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.04.018 · Cited by 416 · see citing works
Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.34 · Cited by 383 · see citing works
Oxytocin enhances brain function in children with autism
Gordon, I., Vander Wyk, B. C., Bennett, R. H., Cordeaux, C., Lucas, M. V., Eilbott, J. A., Zagoory-Sharon, O., Leckman, J. F., Feldman, R., & Pelphrey, K. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1312857110 · Cited by 336 · see citing works
Priming, Replication, and the Hardest Science
Cesario, J. (2014) · Perspectives on Psychological Science · doi:10.1177/1745691613513470 · Cited by 320 · see citing works
The neuroendocrinology of the microbiota-gut-brain axis: a behavioural perspective
Cussotto, S., Sandhu, K. V., Dinan, T. G., & Cryan, J. F. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.04.002 · Cited by 326 · see citing works
van Anders, S. M., Goldey, K. L., & Kuo, P. X. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.06.001 · Cited by 321 · see citing works
Does Oxytocin Increase Trust in Humans? A Critical Review of Research
Nave, G., Camerer, C., & McCullough, M. (2015) · Perspectives on Psychological Science · doi:10.1177/1745691615600138 · Cited by 309 · see citing works
De Dreu, C. K. W., & Kret, M. E. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.03.020 · Cited by 297 · see citing works
Bethlehem, R. A. I., van Honk, J., Auyeung, B., & Baron-Cohen, S. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.10.011 · Cited by 285 · see citing works
The animal and human neuroendocrinology of social cognition, motivation and behavior
McCall, C., & Singer, T. (2012) · Nature Neuroscience · doi:10.1038/nn.3084 · Cited by 273 · see citing works
Weisman, O., Zagoory-Sharon, O., & Feldman, R. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.011 · Cited by 240 · see citing works
The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies
Modi, M. E., & Young, L. J. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.010 · Cited by 218 · see citing works
Oxytocin and social motivation
Gordon, I., Martin, C., Feldman, R., & Leckman, J. F. (2011) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2011.07.007 · Cited by 211 · see citing works
Deconstructing sociality, social evolution and relevant nonapeptide functions
Goodson, J. L. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.12.005 · Cited by 206 · see citing works
Riem, M. M. E., van IJzendoorn, M. H., Tops, M., Boksem, M. A. S., Rombouts, S. A. R. B., & Bakermans-Kranenburg, M. J. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2011.313 · Cited by 191 · see citing works
Testosterone inhibits trust but promotes reciprocity
Boksem, M. A. S., Mehta, P. H., Van den Bergh, B., van Son, V., Trautmann, S. T., Roelofs, K., Smidts, A., & Sanfey, A. G. (2013) · Psychological Science · doi:10.1177/0956797613495063 · Cited by 191 · see citing works
Human neuroimaging of oxytocin and vasopressin in social cognition
Zink, C. F., & Meyer-Lindenberg, A. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2012.01.016 · Cited by 176 · see citing works
Intranasal administration of oxytocin: behavioral and clinical effects, a review
Veening, J. G., & Olivier, B. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.04.012 · Cited by 169 · see citing works
Kamilar-Britt, P., & Bedi, G. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.08.016 · Cited by 163 · see citing works
Effects of MDMA and intranasal oxytocin on social and emotional processing
Kirkpatrick, M. G., Lee, R., Wardle, M. C., Jacob, S., & de Wit, H. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.12 · Cited by 143 · see citing works
Nightmares: prevalence among the Finnish general adult population and war veterans during 1972-2007
Sandman, N., Valli, K., Kronholm, E., Ollila, H. M., Revonsuo, A., Laatikainen, T., & Paunio, T. (2013) · Sleep · doi:10.5665/sleep.2806 · Cited by 139 · see citing works
Riem, M. M. E., Bakermans-Kranenburg, M. J., van IJzendoorn, M. H., Out, D., & Rombouts, S. A. R. B. (2012) · Attachment & Human Development · doi:10.1080/14616734.2012.727252 · Cited by 134 · see citing works
A three-phase model of the social emotional functioning in eating disorders
Treasure, J., Corfield, F., & Cardi, V. (2012) · European Eating Disorders Review · doi:10.1002/erv.2181 · Cited by 128 · see citing works
Dai, L., Carter, C. S., Ying, J., Bellugi, U., Pournajafi-Nazarloo, H., & Korenberg, J. R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038513 · Cited by 119 · see citing works
Bethlehem, R. A. I., Baron-Cohen, S., van Honk, J., Auyeung, B., & Bos, P. A. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00048 · Cited by 120 · see citing works
Self-citationSex, Receptors, and Attachment: A Review of Individual Factors Influencing Response to Oxytocin
MacDonald, K. S. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00194 · Cited by 119 · see citing works
Oxytocin facilitates social approach behavior in women
Preckel, K., Scheele, D., Kendrick, K. M., Maier, W., & Hurlemann, R. (2014) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2014.00191 · Cited by 111 · see citing works
Ditzen, B., Nater, U. M., Schaer, M., La Marca, R., Bodenmann, G., Ehlert, U., & Heinrichs, M. (2013) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nss083 · Cited by 111 · see citing works
“Using this technique, an increasing number of human studies suggest effects of OT on the level of behavioral and neural systems, including social interaction, social memory and stress reactivity (Heinrichs et al., 2009; Bos et al., 2011; Meyer-Lindenberg et al., 2011).”
MethodTerburg, D., & van Honk, J. (2013) · Emotion Review · doi:10.1177/1754073913477510 · Cited by 107 · see citing works
Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans
Kirkpatrick, M. G., Francis, S. M., Lee, R., de Wit, H., & Jacob, S. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.04.006 · Cited by 106 · see citing works
Oxytocin and stress-related disorders: neurobiological mechanisms and treatment opportunities
Sippel, L. M., Allington, C. E., Pietrzak, R. H., Harpaz-Rotem, I., Mayes, L. C., & Olff, M. (2017) · Chronic Stress · doi:10.1177/2470547016687996 · Cited by 99 · see citing works
Sex differences in effective fronto-limbic connectivity during negative emotion processing
Lungu, O., Potvin, S., Tikàsz, A., & Mendrek, A. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.08.012 · Cited by 96 · see citing works
Oxytocin effects on complex brain networks are moderated by experiences of maternal love withdrawal
Riem, M. M. E., van IJzendoorn, M. H., Tops, M., Boksem, M. A. S., Rombouts, S. A. R. B., & Bakermans-Kranenburg, M. J. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.01.011 · Cited by 91 · see citing works
Testosterone Modulates Altered Prefrontal Control of Emotional Actions in Psychopathic Offenders
Volman, I., von Borries, A. K. L., Bulten, B. H., Verkes, R. J., Toni, I., & Roelofs, K. (2016) · eneuro · doi:10.1523/eneuro.0107-15.2016 · Cited by 91 · see citing works
The heart of the story: Peripheral physiology during narrative exposure predicts charitable giving
Barraza, J. A., Alexander, V., Beavin, L. E., Terris, E. T., & Zak, P. J. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2015.01.008 · Cited by 90 · see citing works
Peters, S., Jolles, D. J., Duijvenvoorde, A. C. K. V., Crone, E. A., & Peper, J. S. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.01.004 · Cited by 88 · see citing works
Oxytocin’s effect on resting-state functional connectivity varies by age and sex
Ebner, N. C., Chen, H., Porges, E., Lin, T., Fischer, H., Feifel, D., & Cohen, R. A. (2016) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2016.03.013 · Cited by 84 · see citing works
van IJzendoorn, M. H., Huffmeijer, R., Alink, L. R. A., Bakermans-Kranenburg, M. J., & Tops, M. (2011) · Frontiers in Psychology · doi:10.3389/fpsyg.2011.00258 · Cited by 83 · see citing works
Oxytocin reduces neural activity in the pain circuitry when seeing pain in others
Bos, P. A., Montoya, E. R., Hermans, E. J., Keysers, C., & van Honk, J. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.03.049 · Cited by 72 · see citing works
Self-citationTollenaar, M. S., Chatzimanoli, M., van der Wee, N. J. A., & Putman, P. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.02.018 · Cited by 68 · see citing works
Oxytocin improves emotion recognition for older males
Campbell, A., Ruffman, T., Murray, J. E., & Glue, P. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.04.021 · Cited by 63 · see citing works
Strongly bonded family members in common marmosets show synchronized fluctuations in oxytocin
Finkenwirth, C., van Schaik, C., Ziegler, T. E., & Burkart, J. M. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.07.034 · Cited by 59 · see citing works
Oxytocin and anxiety disorders
Gottschalk, M. G., & Domschke, K. (2017) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2017_25 · Cited by 61 · see citing works
Oxytocin sharpens self-other perceptual boundary
Colonnello, V., Chen, F. S., Panksepp, J., & Heinrichs, M. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.08.010 · Cited by 58 · see citing works
Self-citationBosch, O. G., Eisenegger, C., Gertsch, J., von Rotz, R., Dornbierer, D., Gachet, M. S., Heinrichs, M., Wetter, T. C., Seifritz, E., & Quednow, B. B. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.07.167 · Cited by 42 · see citing works
Oxytocin and vulnerable romantic relationships
Grebe, N. M., Kristoffersen, A. A., Grøntvedt, T. V., Emery Thompson, M., Kennair, L. E. O., & Gangestad, S. W. (2017) · Hormones and Behavior · doi:10.1016/j.yhbeh.2017.02.009 · Cited by 34 · see citing works
McKenna, B. G., Huang, Y., Vervier, K., Hofammann, D., Cafferata, M., Al-Momani, S., Lowenthal, F., Zhang, A., Koh, J.-Y., Thenuwara, S., et al. (2021) · Molecular Autism · doi:10.1186/s13229-021-00450-w · Cited by 11 · see citing works
- Authors
- Bos, P. A., Panksepp, J., Bluthé, R.-M., & Honk, J. V.
- Affiliations
- Utrecht University (NL)
- Washington State University (US)
- Université de Bordeaux (FR)
- University of Cape Town (ZA)
- Corresponding author
- Bos, Peter A.
- Venue
- Frontiers in Neuroendocrinology
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 33
- Issue
- 1
- Pages
- 17-35
- ISSN
- 0091-3022 (ISSN-L)
- OpenAlex
- W2043985159
- Semantic Scholar
- 7906dfe3cc9cedbb3e5a82bb4c4025ed090790ce
- Cited by
- 429
- References
- 227
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 9 · 2023: 16 · 2022: 18 · 2021: 19 · 2020: 19 · 2019: 33 · 2018: 23 · 2017: 31 · 2016: 38 · 2015: 51 · 2014: 43 · 2013: 56 · 2012: 38
- FWCI
- 6.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Frontiers in Neuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Evolutionary Psychology and Human Behavior
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Keywords
- social-emotional behavior, neuroendocrinology, testosterone, estradiol, oxytocin, vasopressin, neuropeptides, steroid hormones, human social behavior
- MeSH terms
- Aggression, Animals, Arginine Vasopressin, Emotions, Empathy, Estradiol, Humans, Models, Neurological, Object Attachment, Oxytocin, Social Behavior, Social Perception, Testosterone, Vasopressins
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