Deconstructing sociality, social evolution and relevant nonapeptide functions
Abstract
Although behavioral neuroendocrinologists often discuss "sociality" as a unitary variable, the term encompasses a wide diversity of behaviors that do not evolve in a linked fashion across species. Thus grouping, monogamy, paternal care, cooperative breeding/alloparental care, and various other forms of social contact are evolutionarily labile and evolve in an almost cafeteria-like fashion, indicating that relevant neural mechanisms are at least partially dissociable. This poses a challenge for the study of the nonapeptides (vasopressin, oxytocin, and homologous neuropeptides), because nonapeptides are known to modulate all of these aspects of sociality in one species or another. Hence, we may expect substantial diversity in the behavioral functions of nonapeptides across species, and indeed this is the case. Further compounding this complexity is the fact that the pleiotropic contributions of nonapeptides to social behavior are matched by pleiotropic contributions to physiology. Given these considerations, single "model systems" approaches to nonapeptide function will likely not have strong predictive validity for humans or other species. Rather, if we are to achieve predictive validity, we must sample a wide diversity of species in an attempt to derive general principles. In the present review, I discuss what is known about functional evolution of nonapeptide systems, and critically evaluate general assumptions about bonding and other functions that are based on the model systems approach. From this analysis I attempt to summarize what can and cannot be generalized across species, and highlight critical gaps in our knowledge about the functional evolution of nonapeptide systems as it relates to dimensions of sociality.
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Injection of an OTR antagonist into the LS can reduce social preference.
“This variation in the distribution of OTR in these birds is functional, and an injection of an OTR antagonist into the LS can reduce social preference (Goodson 2013).”
From A precision medicine approach to oxytocin trials (2017) · cites this paper as Goodson 2013
Neuropeptide effects are highly diverse across species and social situations.
“It is also evident that these neuropeptide effects are highly diverse across species and social situations (Goodson, 2013).”
From Inequity aversion strategies between marmosets are influenced by partner familiarity and sex but not by oxytocin (2016) · cites this paper as Goodson, 2013
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“Our results also show that AVP can contribute to cooperation among men, and call for greater investigation of its role as a potential treatment for males with ASD, although potential pleitropic effects on stress and anxiety should be carefully investigated (Goodson, 2013; Shalev, et al., 2011).”
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- Authors
- Goodson, J. L.
- Affiliations
- Indiana University Bloomington (US)
- Corresponding author
- Goodson, James L.
- Venue
- Psychoneuroendocrinology
- Publisher
- Elsevier BV
- Published
- 2013-04
- Volume
- 38
- Issue
- 4
- Pages
- 465-478
- ISSN
- 0306-4530 (ISSN-L)
- OpenAlex
- W2009060360
- Semantic Scholar
- 824b7840d4f7c648636a50874bbe5870bf0d433d
- Cited by
- 206
- References
- 133
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 6 · 2022: 11 · 2021: 17 · 2020: 23 · 2019: 29 · 2018: 13 · 2017: 21 · 2016: 17 · 2015: 29 · 2014: 21 · 2013: 14
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychoneuroendocrinology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Evolutionary Psychology and Human Behavior
- Keywords
- nonapeptide, vasopressin, oxytocin, sociality, social evolution, monogamy, paternal care, cooperative breeding, alloparental care, social bonding, functional evolution, model systems, cross-species generalization, pleiotropy
- MeSH terms
- Animals, Behavior, Animal, Biological Evolution, Humans, Object Attachment, Oxytocin, Social Behavior, Vasopressins, Vasotocin
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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