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Synaptic circuit remodelling by matrix metalloproteinases in health and disease

Huntley, George W.·2012·Nature Reviews Neuroscience
DOI 10.1038/nrn3320PMC PMC4900464
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  • MMPs have been implicated in regulating synaptic remodeling and maintaining the blood‒brain barrier (BBB) by altering ECM components.

    “Although MMPs have been implicated in regulating synaptic remodeling and maintaining the blood‒brain barrier (BBB) by altering ECM components11,12, little is known about the effects of MMPs in the context of cognitive aging.”

    From MT1-MMP inhibition rejuvenates ageing brain and rescues cognitive deficits in obesity (2025) · cites this paper as [12]

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Metadata

Authors
Huntley, G. W.
Venue
Nature Reviews Neuroscience
Publisher
Springer Science and Business Media LLC
Published
2012-10-10
Volume
13
Issue
11
Pages
743-757
ISSN
  • 1471-003X
  • 1471-0048
DOI
10.1038/nrn3320
PMC
PMC4900464
Cited by
267
References
23
Language
en
Licence
www.springer.com/tdm (tdm)

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