Photovoltaic retinal prosthesis restores high-resolution responses to single-pixel stimulation in blind retinas
Open accessPublished version of a preprint
Abstract
Abstract Retinal prostheses hold the promise of restoring vision in totally blind people. However, a decade of clinical trials highlighted quantitative limitations hampering the possibility of reaching this goal. A key challenge in retinal stimulation is to independently activate retinal neurons over a large portion of the subject’s visual field. Reaching such a goal would significantly improve the perception accuracy in retinal implants’ users, along with their spatial cognition, attention, ambient mapping and interaction with the environment. Here we show a wide-field, high-density and high-resolution photovoltaic epiretinal prosthesis for artificial vision (POLYRETINA). The prosthesis embeds 10,498 physically and functionally independent photovoltaic pixels, allowing for wide retinal coverage and high-resolution stimulation. Single-pixel illumination reproducibly induced network-mediated responses from retinal ganglion cells at safe irradiance levels. Furthermore, POLYRETINA allowed response discrimination with a high spatial resolution equivalent to the pixel pitch (120 µm) thanks to the network-mediated stimulation mechanism. This approach could allow mid-peripheral artificial vision in patients with retinitis pigmentosa.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
POLYRETINA reported ex-vivo a spatial resolution of 120 μm (or 20/480) equivalent to the electrode separation.
“POLYRETINA reported ex-vivo a spatial resolution of 120 µm (or 20/480) equivalent to the electrode separation [132].”
From Advances in visual prostheses: engineering and biological challenges (2022) · cites this paper as [132]
POLYRETINA is a high-density wide-field epiretinal prosthesis containing 10,498 photovoltaic pixels distributed over an active area of approximately 43°.
“POLYRETINA is a high-density wide-field epiretinal prosthesis containing 10 498 photovoltaic pixels distributed over an active area of approximately 43 • [38,39,131,132].”
From Advances in visual prostheses: engineering and biological challenges (2022) · cites this paper as [132]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Unsupervised spike detection and sorting with wavelets and superparamagnetic clustering
Quiroga, R. Q., Nadasdy, Z., & Ben-Shaul, Y. (2004) · Neural Computation · doi:10.1162/089976604774201631 · Cited by 2,119 · see citing works
The functional diversity of retinal ganglion cells in the mouse
Baden, T., Berens, P., Franke, K., Román Rosón, M., Bethge, M., & Euler, T. (2016) · Nature · doi:10.1038/nature16468 · Cited by 999 · see citing works
Hamel, C. (2006) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-1-40 · Cited by 962 · see citing works
Perceptual grouping and attention in visual search for features and for objects.
Treisman, A. (1982) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037/0096-1523.8.2.194 · Cited by 908 · see citing works
Subretinal electronic chips allow blind patients to read letters and combine them to words
Zrenner, E., Bartz-Schmidt, K. U., Benav, H., Besch, D., Bruckmann, A., Gabel, V.-P., Gekeler, F., Greppmaier, U., Harscher, A., Kibbel, S., et al. (2011) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2010.1747 · Cited by 819 · see citing works
Interim results from the international trial of Second Sight's visual prosthesis
Humayun, M. S., Dorn, J. D., da Cruz, L., Dagnelie, G., Sahel, J.-A., Stanga, P. E., Cideciyan, A. V., Duncan, J. L., Eliott, D., Filley, E., et al. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2011.09.028 · Cited by 700 · see citing works
Hot exciton dissociation in polymer solar cells
Grancini, G., Maiuri, M., Fazzi, D., Petrozza, A., Egelhaaf, H., Brida, D., Cerullo, G., & Lanzani, G. (2012) · Nature Materials · doi:10.1038/nmat3502 · Cited by 659 · see citing works
Gargini, C., Tozzini, E. T., Mazzoni, F., & Strettoi, E. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.21144 · Cited by 496 · see citing works
Dendritic field size and morphology of midget and parasol ganglion cells of the human retina.
Dacey, D. M., & Petersen, M. R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.20.9666 · Cited by 495 · see citing works
Maximum permissible exposures for ocular safety (ANSI 2000), with emphasis on ophthalmic devices
Delori, F. C., Webb, R. H., & Sliney, D. H. (2007) · Journal of the Optical Society of America A · doi:10.1364/josaa.24.001250 · Cited by 484 · see citing works
The mosaic of midget ganglion cells in the human retina
Dacey, D. (1993) · The Journal of Neuroscience · doi:10.1523/jneurosci.13-12-05334.1993 · Cited by 480 · see citing works
Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Braun, A., Bruckmann, A., Gekeler, F., Greppmaier, U., Hipp, S., Hörtdörfer, G., Kernstock, C., et al. (2013) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2013.0077 · Cited by 473 · see citing works
Photovoltaic retinal prosthesis with high pixel density
Mathieson, K., Loudin, J., Goetz, G. A., Huie, P., Wang, L., Kamins, T. I., Galambos, L., Smith, R., Harris, J. S., Sher, A., et al. (2012) · Nature Photonics · doi:10.1038/nphoton.2012.104 · Cited by 460 · see citing works
A neural interface for a cortical vision prosthesis
Normann, R. A., Maynard, E. M., Rousche, P. J., & Warren, D. J. (1999) · Vision Research · doi:10.1016/s0042-6989(99)00040-1 · Cited by 411 · see citing works
Veraart, C., Raftopoulos, C., Mortimer, J. T., Delbeke, J., Pins, D., Michaux, G., Vanlierde, A., Parrini, S., & Wanet-Defalque, M.-C. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00977-9 · Cited by 407 · see citing works
Chang, B., Hawes, N. L., Pardue, M. T., German, A. M., Hurd, R. E., Davisson, M. T., Nusinowitz, S., Rengarajan, K., Boyd, A. P., Sidney, S. S., et al. (2007) · Vision Research · doi:10.1016/j.visres.2006.11.020 · Cited by 395 · see citing works
Subretinal visual implant alpha IMS - clinical trial interim report
Stingl, K., Bartz-Schmidt, K. U., Besch, D., Chee, C. K., Cottriall, C. L., Gekeler, F., Groppe, M., Jackson, T. L., MacLaren, R. E., Koitschev, A., et al. (2015) · Vision Research · doi:10.1016/j.visres.2015.03.001 · Cited by 387 · see citing works
Mechanical characterization of PEDOT:PSS thin films
Lang, U., Naujoks, N., & Dual, J. (2008) · Synthetic Metals · doi:10.1016/j.synthmet.2008.11.005 · Cited by 366 · see citing works
Five-year safety and performance results from the argus II retinal prosthesis system clinical trial.
da Cruz, L., Dorn, J. D., Humayun, M. S., Dagnelie, G., Handa, J., Barale, P.-O., Sahel, J.-A., Stanga, P. E., Hafezi, F., Safran, A. B., et al. (2016) · Ophthalmology · doi:10.1016/j.ophtha.2016.06.049 · Cited by 359 · see citing works
The Argus® II Retinal Prosthesis System
Luo, Y. H.-L., & da Cruz, L. (2016) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.09.003 · Cited by 351 · see citing works
Photovoltaic restoration of sight with high visual acuity
Lorach, H., Goetz, G., Smith, R., Lei, X., Mandel, Y., Kamins, T. I., Mathieson, K., Huie, P., Harris, J. S., Sher, A., et al. (2015) · Nature Medicine · doi:10.1038/nm.3851 · Cited by 341 · see citing works
Design of a high-resolution optoelectronic retinal prosthesis
Palanker, D., Vankov, A., Huie, P., & Baccus, S. A. (2005) · Journal of Neural Engineering · doi:10.1088/1741-2560/2/1/012 · Cited by 330 · see citing works
A polymer optoelectronic interface restores light sensitivity in blind rat retinas
Ghezzi, D., Antognazza, M. R., Maccarone, R., Bellani, S., Lanzarini, E., Martino, N., Mete, M., Pertile, G., Bisti, S., Lanzani, G., et al. (2013) · Nature Photonics · doi:10.1038/nphoton.2013.34 · Cited by 327 · see citing works
Self-citationA hybrid bioorganic interface for neuronal photoactivation
Ghezzi, D., Antognazza, M. R., Maschio, M. D., Lanzarini, E., Benfenati, F., & Lanzani, G. (2011) · Nature Communications · doi:10.1038/ncomms1164 · Cited by 305 · see citing works
Self-citationA fully organic retinal prosthesis restores vision in a rat model of degenerative blindness
Maya‐Vetencourt, J. F., Ghezzi, D., Antognazza, M. R., Colombo, E., Mete, M., Feyen, P., Desii, A., Buschiazzo, A., Paolo, M. D., Marco, S. D., et al. (2017) · Nature Materials · doi:10.1038/nmat4874 · Cited by 290 · see citing works
Self-citationAhuja, A. K., Dorn, J. D., Caspi, A., McMahon, M. J., Dagnelie, G., daCruz, L., Stanga, P., Humayun, M. S., Greenberg, R. J., & Argus II Study Group (2011) · British Journal of Ophthalmology · doi:10.1136/bjo.2010.179622 · Cited by 289 · see citing works
Retinal stimulation strategies to restore vision: fundamentals and systems
Yue, L., Weiland, J. D., Roska, B., & Humayun, M. S. (2016) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2016.05.002 · Cited by 272 · see citing works
Ganglion cell distribution in the retina of the mouse.
Dräger, U. C., & Olsen, J. F. (1981) · PubMed · Cited by 262 · see citing works
Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind
Ho, A. C., Humayun, M. S., Dorn, J. D., da Cruz, L., Dagnelie, G., Handa, J. T., Barale, P. O., Sahel, J., Stanga, P. E., Hafezi, F., et al. (2015) · Ophthalmology · doi:10.1016/j.ophtha.2015.04.032 · Cited by 262 · see citing works
Savagatrup, S., Printz, A. D., O’Connor, T. F., Zaretski, A. V., Rodriquez, D., Sawyer, E. J., Rajan, K. M., Acosta, R. I., Root, S. E., & Lipomi, D. J. (2014) · Energy & Environmental Science · doi:10.1039/c4ee02657h · Cited by 256 · see citing works
“Braille” reading by a blind volunteer by visual cortex stimulation
DOBELLE, W. H., MLADEJOVSKY, M. G., EVANS, J. R., ROBERTS, T. S., & GIRVIN, J. P. (1976) · Nature · doi:10.1038/259111a0 · Cited by 253 · see citing works
Hammer, M., Roggan, A., Schweitzer, D., & Müller, G. (1995) · Physics in Medicine and Biology · doi:10.1088/0031-9155/40/6/001 · Cited by 249 · see citing works
Mazzoni, F., Novelli, E., & Strettoi, E. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4968-08.2008 · Cited by 245 · see citing works
Four alpha ganglion cell types in mouse retina: Function, structure, and molecular signatures
Krieger, B. M., Qiao, M., Rousso, D. L., Sanes, J. R., & Meister, M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180091 · Cited by 242 · see citing works
In Vivo Human Choroidal Thickness Measurements: Evidence for Diurnal Fluctuations
Brown, J. S., Flitcroft, D. I., Ying, G., Francis, E. L., Schmid, G., Quinn, G. E., & Stone, R. A. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-1779 · Cited by 241 · see citing works
Lewis, P. M., Ackland, H. M., Lowery, A. J., & Rosenfeld, J. V. (2015) · Brain Research · doi:10.1016/j.brainres.2014.11.020 · Cited by 228 · see citing works
Photovoltaic Restoration of Central Vision in Atrophic Age-Related Macular Degeneration
Palanker, D., Le Mer, Y., Mohand-Said, S., Muqit, M., & Sahel, J. A. (2020) · Ophthalmology · doi:10.1016/j.ophtha.2020.02.024 · Cited by 227 · see citing works
Mobility performance with a pixelized vision system.
Cha, K., Horch, K. W., & Normann, R. A. (1992) · Vision Research · doi:10.1016/0042-6989(92)90229-c · Cited by 226 · see citing works
Edwards, T. L., Cottriall, C. L., Xue, K., Simunovic, M. P., Ramsden, J. D., Zrenner, E., & MacLaren, R. E. (2018) · Ophthalmology · doi:10.1016/j.ophtha.2017.09.019 · Cited by 193 · see citing works
Retinal implants: a systematic review: Table 1
Chuang, A., Margo, C. E., & Greenberg, P. B. (2014) · British Journal of Ophthalmology · doi:10.1136/bjophthalmol-2013-303708 · Cited by 192 · see citing works
Fighting Blindness with Microelectronics
Zrenner, E. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3007399 · Cited by 192 · see citing works
Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesis
Ferlauto, L., Airaghi Leccardi, M. J. I., Chenais, N. A. L., Gilliéron, S. C. A., Vagni, P., Bevilacqua, M., Wolfensberger, T. J., Sivula, K., & Ghezzi, D. (2018) · Nature Communications · doi:10.1038/s41467-018-03386-7 · Cited by 183 · see citing works
Self-citationDorn, J. D., Ahuja, A. K., Caspi, A., da Cruz, L., Dagnelie, G., Sahel, J.-A., Greenberg, R. J., McMahon, M. J., & Argus II Study Group, F. T. (2013) · JAMA Ophthalmology · doi:10.1001/2013.jamaophthalmol.221 · Cited by 177 · see citing works
Improving the spatial resolution of epiretinal implants by increasing stimulus pulse duration
Weitz, A. C., Nanduri, D., Behrend, M. R., Gonzalez-Calle, A., Greenberg, R. J., Humayun, M. S., Chow, R. H., & Weiland, J. D. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aac4877 · Cited by 154 · see citing works
Pennesi, M. E., Michaels, K. V., Magee, S. S., Maricle, A., Davin, S., Garg, A., Gale, M. J., Tu, D. C., Wen, Y., Erker, L. R., et al. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-9611 · Cited by 151 · see citing works
Boinagrov, D., Pangratz-Fuehrer, S., Goetz, G., & Palanker, D. (2014) · Journal of Neural Engineering · doi:10.1088/1741-2560/11/2/026008 · Cited by 146 · see citing works
Nanowire arrays restore vision in blind mice
Tang, J., Qin, N., Chong, Y., Diao, Y., Yiliguma, Wang, Z., Xue, T., Jiang, M., Zhang, J., & Zheng, G. (2018) · Nature Communications · doi:10.1038/s41467-018-03212-0 · Cited by 144 · see citing works
Real and virtual mobility performance in simulated prosthetic vision
Dagnelie, G., Keane, P. A., Narla, V., Yang, L., Weiland, J. D., & Humayun, M. S. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/1/s11 · Cited by 131 · see citing works
Face recognition in age-related maculopathy.
Bullimore, M. A., Bailey, I. L., & Wacker, R. T. (1991) · PubMed · Cited by 128 · see citing works
A Polymer Optoelectronic Interface Provides Visual Cues to a Blind Retina
Gautam, V., Rand, D., Hanein, Y., & Narayan, K. S. (2013) · Advanced Materials · doi:10.1002/adma.201304368 · Cited by 127 · see citing works
Responses of ganglion cells to repetitive electrical stimulation of the retina
Jensen, R. J., & Rizzo, J. F. (2007) · Journal of Neural Engineering · doi:10.1088/1741-2560/4/1/s01 · Cited by 121 · see citing works
Visual attention and perceptual grouping
Ben-Av, M. B., Sagi, D., & Braun, J. (1992) · Perception & Psychophysics · doi:10.3758/bf03209145 · Cited by 118 · see citing works
Stasheff, S. F., Shankar, M., & Andrews, M. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00704.2010 · Cited by 117 · see citing works
Depression and the vision-related quality of life in patients with retinitis pigmentosa
Hahm, B.-J., Shin, Y.-W., Shim, E.-J., Jeon, H.-J., Seo, J.-M., Chung, H., & Yu, H. G. (2008) · British Journal of Ophthalmology · doi:10.1136/bjo.2007.127092 · Cited by 109 · see citing works
Resolution of the epiretinal prosthesis is not limited by electrode size
Behrend, M. R., Ahuja, A. K., Humayun, M. S., Chow, R. H., & Weiland, J. D. (2011) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2011.2140132 · Cited by 102 · see citing works
Beyeler, M., Rokem, A., Boynton, G. M., & Fine, I. (2017) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa795e · Cited by 102 · see citing works
Near‐Infrared Tandem Organic Photodiodes for Future Application in Artificial Retinal Implants
Simone, G., Rasi, D. D. C., de Vries, X., Heintges, G. H. L., Meskers, S. C. J., Janssen, R. A. J., & Gelinck, G. H. (2018) · Advanced Materials · doi:10.1002/adma.201804678 · Cited by 100 · see citing works
Thermal Elevation in the Human Eye and Head Due to the Operation of a Retinal Prosthesis
Gosalia, K. C., Weiland, J. D., Humayun, M. S., & Lazzi, G. (2004) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2004.827548 · Cited by 95 · see citing works
Light-evoked hyperpolarization and silencing of neurons by conjugated polymers
Feyen, P., Colombo, E., Endeman, D., Nova, M., Laudato, L., Martino, N., Antognazza, M. R., Lanzani, G., Benfenati, F., & Ghezzi, D. (2016) · Scientific Reports · doi:10.1038/srep22718 · Cited by 94 · see citing works
Self-citationDagnelie, G., Christopher, P., Arditi, A. R., da Cruz, L., Duncan, J. L., Ho, A. C., de Koo, L. C. O., Sahel, J., Stanga, P. E., Thumann, G., et al. (2016) · Clinical and Experimental Ophthalmology · doi:10.1111/ceo.12812 · Cited by 93 · see citing works
Jacoby, J., & Schwartz, G. W. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.2804-16.2016 · Cited by 92 · see citing works
Detection of coherent movement in peripherally viewed random-dot patterns
van de GRIND, W. A., van Doorn, A. J., & Koenderink, J. J. (1983) · Journal of the Optical Society of America · doi:10.1364/josa.73.001674 · Cited by 91 · see citing works
Antognazza, M. R., Paolo, M. D., Ghezzi, D., Mete, M., Marco, S. D., Maya‐Vetencourt, J. F., Maccarone, R., Desii, A., Fonzo, F. D., Bramini, M., et al. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201600318 · Cited by 89 · see citing works
Self-citationRetinal prostheses: progress toward the next generation implants
Ghezzi, D. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00290 · Cited by 83 · see citing works
Self-citationErickson-Davis, C., & Korzybska, H. (2021) · PLoS ONE · doi:10.1371/journal.pone.0229189 · Cited by 83 · see citing works
Neural Mechanisms Mediating Motion Sensitivity in Parasol Ganglion Cells of the Primate Retina
Manookin, M. B., Patterson, S. S., & Linehan, C. M. (2018) · Neuron · doi:10.1016/j.neuron.2018.02.006 · Cited by 82 · see citing works
Multiple components of ganglion cell desensitization in response to prosthetic stimulation
Freeman, D. K., & Fried, S. I. (2011) · Journal of Neural Engineering · doi:10.1088/1741-2560/8/1/016008 · Cited by 80 · see citing works
Cellular Origin of Spontaneous Ganglion Cell Spike Activity in Animal Models of Retinitis Pigmentosa
Margolis, D. J., & Detwiler, P. B. (2010) · Journal of Ophthalmology · doi:10.1155/2011/507037 · Cited by 78 · see citing works
Young's modulus, fracture strain, and tensile strength of sputtered titanium thin films
Tsuchiya, T., Hirata, M., & Chiba, N. (2005) · Thin Solid Films · doi:10.1016/j.tsf.2005.02.024 · Cited by 77 · see citing works
Spatially selective activation of the visual cortex via intraneural stimulation of the optic nerve
Gaillet, V., Cutrone, A., Artoni, F., Vagni, P., Mega Pratiwi, A., Romero, S. A., Lipucci Di Paola, D., Micera, S., & Ghezzi, D. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0446-8 · Cited by 73 · see citing works
Self-citationBasic Quantitative Assessment of Visual Performance in Patients with Very Low Vision
Bach, M., Wilke, M., Wilhelm, B., Zrenner, E., & Wilke, R. G. H. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.09-3512 · Cited by 70 · see citing works
Behavioural responses to a photovoltaic subretinal prosthesis implanted in non-human primates
Prévot, P.-H., Gehere, K., Arcizet, F., Akolkar, H., Khoei, M. A., Blaize, K., Oubari, O., Daye, P. M., Lanoë, M., Valet, M., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0484-2 · Cited by 69 · see citing works
Contribution of two movement detecting mechanisms to central and peripheral vision
Murray, I. J., MacCana, F., & Kulikowski, J. J. (1983) · Vision Research · doi:10.1016/0042-6989(83)90138-4 · Cited by 67 · see citing works
Stimulation strategies for improving the resolution of retinal prostheses
Tong, W., Meffin, H., Garrett, D. J., & Ibbotson, M. R. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00262 · Cited by 66 · see citing works
Mechanical Behavior and Anisotropy of Spin-Coated SU-8 Thin Films for MEMS
Robin, C. J., Vishnoi, A., & Jonnalagadda, K. N. (2013) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2013.2264341 · Cited by 64 · see citing works
Photovoltaic organic interface for neuronal stimulation in the near-infrared
Airaghi Leccardi, M. J. I., Chenais, N. A. L., Ferlauto, L., Kawecki, M., Zollinger, E. G., & Ghezzi, D. (2020) · Communications Materials · doi:10.1038/s43246-020-0023-4 · Cited by 63 · see citing works
Self-citationSimulating prosthetic vision: II. Measuring functional capacity
Chen, S. C., Suaning, G. J., Morley, J. W., & Lovell, N. H. (2009) · Vision Research · doi:10.1016/j.visres.2009.07.003 · Cited by 59 · see citing works
Safety evaluation of “retina implant alpha IMS”—a prospective clinical trial
Kitiratschky, V. B. D., Štingl, K., Wilhelm, B., Peters, T. M., Besch, D., Sachs, H. G., Gekeler, F., Bartz‐Schmidt, K. U., & Zrenner, E. (2014) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-014-2797-x · Cited by 55 · see citing works
Polyimide/SU-8 catheter-tip MEMS gauge pressure sensor
Hasenkamp, W., Forchelet, D., Pataky, K. A., Villard, J., van Lintel, H., Bertsch, A., Wang, Q., & Renaud, P. (2012) · Biomedical Microdevices · doi:10.1007/s10544-012-9661-8 · Cited by 55 · see citing works
Fornos, A. P., Sommerhalder, J., Pittard, A., Safran, A. B., & Pelizzone, M. (2008) · Vision Research · doi:10.1016/j.visres.2008.04.027 · Cited by 50 · see citing works
Michels, R. G., Wilkinson, C. P., Rice, T. A., & Weinberg, A. B. (1991) · Retina · doi:10.1097/00006982-199110000-00031 · Cited by 46 · see citing works
Temperature distribution simulation of the human eye exposed to laser radiation.
Mirnezami, S. A., Jafarabadi, M. R., & Abrishami, M. (2013) · PubMed · Cited by 44 · see citing works
Optical absorption and scattering of bovine cornea, lens and retina in the visible region
Sardar, D. K., Yust, B. G., Barrera, F. J., Mimun, L. C., & Tsin, A. T. C. (2009) · Lasers in Medical Science · doi:10.1007/s10103-009-0677-0 · Cited by 40 · see citing works
Koehler, C. L., Akimov, N. P., & Renterı́a, R. C. (2011) · Journal of Neurophysiology · doi:10.1152/jn.01046.2010 · Cited by 39 · see citing works
Safety Studies for a 44-Channel Suprachoroidal Retinal Prosthesis: A Chronic Passive Study
Abbott, C. J., Nayagam, D. A. X., Luu, C. D., Epp, S. B., Williams, R. A., Rosa, C. M. S.-L., Villalobos, J., McGowan, C. C., Shivdasani, M. N., Burns, O., et al. (2018) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.17-23086 · Cited by 36 · see citing works
Thorn, J. T., Migliorini, E., & Ghezzi, D. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abb5bc · Cited by 34 · see citing works
Self-citationMorphology of wide-field, monostratified ganglion cells of the human retina
Peterson, B. B., & Dacey, D. M. (1999) · Visual Neuroscience · doi:10.1017/s0952523899161066 · Cited by 32 · see citing works
Implantation of modular photovoltaic subretinal prosthesis
Lee, D. Y., Lorach, H., Huie, P., & Palanker, D. (2016) · Ophthalmic Surgery, Lasers and Imaging Retina · doi:10.3928/23258160-20160126-11 · Cited by 30 · see citing works
The very large electrode array for retinal stimulation (VLARS)—A concept study
Lohmann, T., Haiss, F., Schaffrath, K., Schnitzler, A. C., Waschkowski, F., Barz, C. S., van der Meer, A.-M., Werner, C., Johnen, S., Laube, T., et al. (2019) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab4113 · Cited by 29 · see citing works
Retinal safety of near-infrared lasers in cataract surgery
Wang, J. Y., Sramek, C., Paulus, Y. M., Lavinsky, D., Schuele, G., Andersen, D. E., Dewey, D. A., & Palanker, D. (2012) · Journal of Biomedical Optics · doi:10.1117/1.jbo.17.9.095001 · Cited by 28 · see citing works
Direct measurement of bipolar cell responses to electrical stimulation in wholemount mouse retina
Walston, S. T., Chow, R. H.-P., & Weiland, J. D. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aab4ed · Cited by 28 · see citing works
The Subretinal Implant ALPHA: Implantation and Functional Results
Zrenner, E., Bartz-Schmidt, K. U., Besch, D., Gekeler, F., Koitschev, A., Sachs, H. G., & Stingl, K. (2017) · Artificial Vision · doi:10.1007/978-3-319-41876-6_6 · Cited by 27 · see citing works
Lee, J.-I., & Im, M. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aad416 · Cited by 27 · see citing works
Chenais, N. A. L., Leccardi, M. J. I. A., & Ghezzi, D. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abcd6f · Cited by 25 · see citing works
Self-citationChenais, N. A. L., Leccardi, M. J. I. A., & Ghezzi, D. (2019) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab3913 · Cited by 24 · see citing works
Self-citationDetermination of retinal surface area
Nagra, M., Gilmartin, B., Thai, N. J., & Logan, N. S. (2017) · Journal of Anatomy · doi:10.1111/joa.12641 · Cited by 20 · see citing works
Yee, C. W., Toychiev, A. H., Ivanova, E., & Sagdullaev, B. T. (2014) · The Journal of Comparative Neurology · doi:10.1002/cne.23660 · Cited by 17 · see citing works
BIO-HEAT TRANSFER SIMULATION OF SQUARE AND CIRCULAR ARRAY OF RETINAL LASER IRRADIATION
Narasimhan, A., & Jha, K. K. (2011) · Frontiers in Heat and Mass Transfer · doi:10.5098/hmt.v2.3.3005 · Cited by 16 · see citing works
Nanoindentation of Soft Polymers: Modeling, Experiments and Parameter Identification
Chen, Z., & Diebels, S. (2014) · Otto-von-Guericke-Universität Magdeburg · doi:10.24352/ub.ovgu-2017-060 · Cited by 15 · see citing works
Isselé, H., Mercier, D., Guillaume Parry, A., Estevez, R., Vignoud, L., & Olagnon, C. (2012) · e-Journal of Surface Science and Nanotechnology · doi:10.1380/ejssnt.2012.624 · Cited by 14 · see citing works
High‐Frequency Stimulation of Normal and Blind Mouse Retinas Using TiO2 Nanotubes
Ronzani, C., Cottineau, T., González‐Valls, I., Keller, V., Picaud, S. A., Keller, N., & Roux, M. J. (2018) · Advanced Functional Materials · doi:10.1002/adfm.201804639 · Cited by 13 · see citing works
Prospects and Limitations of Spatial Resolution
Sommerhalder, J., & Fornos, A. P. (2016) · Springer eBooks · doi:10.1007/978-3-319-41876-6_4 · Cited by 11 · see citing works
Visual Circuits: Mouse Retina No Longer a Level Playing Field
Dhande, O. S., & Huberman, A. D. (2014) · Current Biology · doi:10.1016/j.cub.2013.12.045 · Cited by 10 · see citing works
Human Factors in Healthcare: A Field Guide to Continuous Improvement
Parush, A. (2017) · Synthesis lectures on assistive, rehabilitative, and health-preserving technologies · doi:10.2200/s00753ed1v01y201701arh011 · Cited by 6 · see citing works
Evidence that L-AP5 and D,L-AP4 can preferentially block cone signals in the rat retina
Green, D. G., & KAPOUSTA-BRUNEAU, N. V. (2007) · Visual Neuroscience · doi:10.1017/s0952523807230123 · Cited by 5 · see citing works
Review: Visual Perception: Physiology, Psychology and Ecology
Smith, A. T. (1997) · Perception · doi:10.1068/p261211 · Cited by 3 · see citing works
Parush, A., Parush, D., & Ilan, R. (2017) · Synthesis lectures on assistive, rehabilitative, and health-preserving technologies · doi:10.1007/978-3-031-01602-8 · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- Gabel, V. P.) 29-45 (Springer International Publishing, 2017).
- Gabel, V. P.) 65-83 (Springer International Publishing, 2017).
- Chuang, A. T., Margo, C. E. & Greenberg, P. B. Retinal implants: a systematic review. Br. J. Ophthalmol. 98, 2013 (2014).
Cited by
Sorted by citations
Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management
Seo, H., Chung, W. G., Kwon, Y. W., Kim, S., Hong, Y., Park, W., Kim, E., Lee, J., Lee, S., Kim, M., et al. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00290 · Cited by 152 · see citing works
Metaverse Wearables for Immersive Digital Healthcare: A Review
Kim, K., Yang, H., Lee, J.-H., & Lee, W. G. (2023) · Advanced Science · doi:10.1002/advs.202303234 · Cited by 105 · see citing works
Monolithic silicon for high spatiotemporal translational photostimulation
Li, P., Zhang, J., Hayashi, H., Yue, J., Li, W., Yang, C., Sun, C., Shi, J., Huberman-Shlaes, J., Hibino, N., et al. (2024) · Nature · doi:10.1038/s41586-024-07016-9 · Cited by 100 · see citing works
Materials for Implantable Surface Electrode Arrays: Current Status and Future Directions
Tringides, C. M., & Mooney, D. J. (2021) · Advanced Materials · doi:10.1002/adma.202107207 · Cited by 70 · see citing works
Retinal Prostheses: Engineering and Clinical Perspectives for Vision Restoration
Wu, K. Y., Mina, M., Sahyoun, J.-Y., Kalevar, A., & Tran, S. D. (2023) · Sensors · doi:10.3390/s23135782 · Cited by 65 · see citing works
POLYRETINA restores light responses in vivo in blind Göttingen minipigs
Vagni, P., Airaghi Leccardi, M. J. I., Vila, C.-H., Zollinger, E. G., Sherafatipour, G., Wolfensberger, T. J., & Ghezzi, D. (2022) · Nature Communications · doi:10.1038/s41467-022-31180-z · Cited by 62 · see citing works
Self-citationHan, M., Yıldız, E., Kaleli, H. N., Karaz, S., Eren, G. O., Dogru-Yuksel, I. B., Şenses, E., Şahin, A., & Nizamoğlu, S. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202102160 · Cited by 59 · see citing works
Karatum, O., Gwak, M.-J., Hyun, J., Önal, A., Koirala, G. R., Kim, T., & Nizamoğlu, S. (2023) · Chemical Society Reviews · doi:10.1039/d2cs01020h · Cited by 54 · see citing works
Advances in visual prostheses: engineering and biological challenges
Borda, E., & Ghezzi, D. (2022) · Progress in Biomedical Engineering · doi:10.1088/2516-1091/ac812c · Cited by 44 · see citing works
Self-citationShi, J., Li, P., Kim, S., & Tian, B. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00285-7 · Cited by 45 · see citing works
Joseph, E., Ciocca, M., Wu, H., Marcozzi, S., Ucci, M. A., Keremane, K. S., Zheng, L., Poudel, B., Wu, C., Camaioni, A., et al. (2024) · npj Biosensing · doi:10.1038/s44328-024-00015-w · Cited by 40 · see citing works
Organic semiconductors for light-mediated neuromodulation
Medagoda, D. I., & Ghezzi, D. (2021) · Communications Materials · doi:10.1038/s43246-021-00217-z · Cited by 39 · see citing works
Self-citationRetinal Organoids and Retinal Prostheses: An Overview
Bellapianta, A., Cetkovic, A., Bolz, M., & Salti, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23062922 · Cited by 38 · see citing works
Flexible optoelectronic sensors: status and prospects
Wang, Z., & Shen, G. (2023) · Materials Chemistry Frontiers · doi:10.1039/d2qm01319c · Cited by 34 · see citing works
Lu, G., Gong, C., Sun, Y., Qian, X., Nair, D. S. R., Li, R., Zeng, Y., Ji, J., Zhang, J., Kang, H., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-48683-6 · Cited by 32 · see citing works
Advanced Sensory Hardware for Intelligent Eye‐Machine Interfacing: from Wearables to Bionics
Wang, Z., Li, S., & Shen, G. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202503519 · Cited by 31 · see citing works
Correlated Activity in the Degenerate Retina Inhibits Focal Response to Electrical Stimulation
Ahn, J., Cha, S., Choi, K.-E., Kim, S., Yoo, Y., & Goo, Y. S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.889663 · Cited by 29 · see citing works
Palanker, D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.24123-0 · Cited by 27 · see citing works
Coghi, P. S., & Coluccini, C. (2024) · Polymers · doi:10.3390/polym16101407 · Cited by 25 · see citing works
Chenais, N. A. L., Leccardi, M. J. I. A., & Ghezzi, D. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abcd6f · Cited by 25 · see citing works
Self-citationExploring Present and Future Directions in Nano-Enhanced Optoelectronic Neuromodulation
Yang, C., Cheng, Z., Li, P., & Tian, B. (2024) · Accounts of Chemical Research · doi:10.1021/acs.accounts.4c00086 · Cited by 24 · see citing works
Physical mechanisms of emerging neuromodulation modalities
Karatum, O., Han, M., Erdoğan, E. T., Karamürsel, S., & Nizamoğlu, S. (2023) · Journal of Neural Engineering · doi:10.1088/1741-2552/acd870 · Cited by 20 · see citing works
Bioinspired and biointegrated vision for artificial sight convergence
Yang, Y., Wang, Y., Zhu, C., Xie, Z., Qin, Z., Wang, Z., & Chai, Y. (2025) · Nature Reviews Bioengineering · doi:10.1038/s44222-025-00324-3 · Cited by 18 · see citing works
Immersive interfaces for clinical applications: current status and future perspective
Chenais, N. A. L., & Görgen, A. (2024) · Frontiers in Neurorobotics · doi:10.3389/fnbot.2024.1362444 · Cited by 18 · see citing works
Self-citationChen, K.-S., Chan, H.-C., & Chan, C.-M. (2025) · Journal of Biological Engineering · doi:10.1186/s13036-025-00548-2 · Cited by 17 · see citing works
Nanoparticle-based optical interfaces for retinal neuromodulation: a review
Stoddart, P. R., Begeng, J. M., Tong, W., Ibbotson, M. R., & Kameneva, T. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1360870 · Cited by 17 · see citing works
Adaptive Interfacial Materials and Implants for Visual Restoration
Zhu, X., Wang, F., Zhao, Q., & Du, X. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202314575 · Cited by 17 · see citing works
Nie, J., Eom, K., AlGhosain, H. M., Neifert, A. R., Cherian, A., Gerbaka, G. M., Ma, K. Y., Liu, T., & Lee, J. (2025) · ACS Nano · doi:10.1021/acsnano.4c14061 · Cited by 16 · see citing works
A review: flexible devices for nerve stimulation
Liu, Z.-Q., Yu, X.-Y., Huang, J., Wu, X.-Y., Wang, Z.-Y., & Zhu, B. (2024) · Soft Science · doi:10.20517/ss.2023.36 · Cited by 15 · see citing works
Yuhong, Z., Liu, X., Ma, J., Wang, Z., Jiang, H., Sun, C., Jeong, D., Guan, H., & Chu, B. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c12460 · Cited by 15 · see citing works
Yang, J., Chen, C., Yu, Z.-Y., Chung, J. H.-Y., Liu, X., Wu, C., & Chen, G. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100253 · Cited by 15 · see citing works
Ciocca, M., Marcozzi, S., Mariani, P., Lacconi, V., Carlo, A. D., Cinà, L., Rosato‐Siri, M. D., Zanon, A., Cattelan, G., Avancini, E., et al. (2023) · Advanced NanoBiomed Research · doi:10.1002/anbr.202200127 · Cited by 14 · see citing works
Balamur, R., Oh, J. T., Karatum, O., Wang, Y., Önal, A., Kaleli, H. N., Pehlivan, Ç., Şahin, A., Hasanreisoğlu, M., Konstantatos, G., et al. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c01964 · Cited by 14 · see citing works
Schaffrath, K., Lohmann, T., Seifert, J., Ingensiep, C., Raffelberg, P., Waschkowski, F., Viga, R., Kokozinski, R., Mokwa, W., Johnen, S., et al. (2021) · BioMedical Engineering OnLine · doi:10.1186/s12938-021-00938-9 · Cited by 15 · see citing works
Agadagba, S. K., Eldaly, A. B. M., & Chan, L. L. H. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.785199 · Cited by 14 · see citing works
Questions about the role of P3HT nanoparticles in retinal stimulation
Palanker, D., Głowacki, E. D., & Ghezzi, D. (2021) · Nature Nanotechnology · doi:10.1038/s41565-021-01044-6 · Cited by 14 · see citing works
Self-citationSherwood, C. P., Crovador, R., Posar, J. A., Brichta, N. M., Simunovic, M. P., Louie, F., Dastoor, P. C., Brichta, A. M., Cairney, J. M., Holmes, N. P., et al. (2023) · Advanced Materials Interfaces · doi:10.1002/admi.202202229 · Cited by 13 · see citing works
Therapeutic landscape for inherited ocular diseases: current and emerging therapies
Chan, H. W., Oh, J., & Leroy, B. P. (2023) · Singapore Medical Journal · doi:10.4103/singaporemedj.smj-2022-179 · Cited by 12 · see citing works
Borda, E., Gaillet, V., Airaghi Leccardi, M. J. I., Zollinger, E. G., Moreira, R. C., & Ghezzi, D. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac6d7e · Cited by 11 · see citing works
Self-citationThorn, J. T., Chenais, N. A. L., Hinrichs, S., Chatelain, M., & Ghezzi, D. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac5a5c · Cited by 11 · see citing works
Self-citationSemantic translation of face image with limited pixels for simulated prosthetic vision
Xia, X., He, X., Lu, F., Pan, X., Li, N., Zhang, J., Pang, X., Yu, F., & Ding, N. (2022) · Information Sciences · doi:10.1016/j.ins.2022.07.094 · Cited by 11 · see citing works
Gaillet, V., Borda, E., Zollinger, E. G., & Ghezzi, D. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/abf523 · Cited by 10 · see citing works
Self-citationThe mechanism of human color vision and potential implanted devices for artificial color vision
Zhang, B., Zhang, R., Zhao, J., Yang, J., & Xu, S. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1408087 · Cited by 11 · see citing works
Neuroprotection, Neuroenhancement, and Neuroregeneration of the Retina and Optic Nerve
Johnson, T. V., Polo, A. D., Sahel, J., & Schuman, J. S. (2022) · Ophthalmology Science · doi:10.1016/j.xops.2022.100216 · Cited by 9 · see citing works
The role of the visual field size in artificial vision
Ghezzi, D. (2023) · Journal of Neural Engineering · doi:10.1088/1741-2552/acc7cd · Cited by 10 · see citing works
Self-citationOptogenetic activation of visual thalamus generates artificial visual percepts
Wang, J., Azimi, H., Zhao, Y., Kaeser, M., Sánchez, P. V., Vázquez‐Guardado, A., Rogers, J. A., Harvey, M., & Rainer, G. (2023) · eLife · doi:10.7554/elife.90431 · Cited by 10 · see citing works
MnO2 Nanoflower Integrated Optoelectronic Biointerfaces for Photostimulation of Neurons
Kaya, L., Karatum, O., Balamur, R., Kaleli, H. N., Önal, A., Vanalakar, S. A., Hasanreisoğlu, M., & Nizamoğlu, S. (2023) · Advanced Science · doi:10.1002/advs.202301854 · Cited by 10 · see citing works
Jo, B., Seo, K., Park, K., Jeong, C., Bathalavaram, P., Lee, M., Ramu, S., Hahm, M. G., & Kim, Y. L. (2024) · Frontiers in Materials · doi:10.3389/fmats.2024.1354522 · Cited by 9 · see citing works
Explainable machine learning predictions of perceptual sensitivity for retinal prostheses
Pogoncheff, G., Hu, Z., Rokem, A., & Beyeler, M. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad310f · Cited by 9 · see citing works
An actor-model framework for visual sensory encoding
Leong, F., Rahmani, B., Psaltis, D., Moser, C., & Ghezzi, D. (2024) · Nature Communications · doi:10.1038/s41467-024-45105-5 · Cited by 8 · see citing works
Self-citationOh, Y., Hong, J., & Kim, J. (2024) · PLoS ONE · doi:10.1371/journal.pone.0305132 · Cited by 8 · see citing works
Joseph, E., Leonardi, C., Nunzio, L. D., Ucci, M. A., Ciocca, M., Mariani, P., Podapangi, S. K., Castriotta, L. A., Vesce, L., Medaglia, P. G., et al. (2025) · Advanced Materials Technologies · doi:10.1002/admt.202501461 · Cited by 7 · see citing works
Double‐Sided, Thin‐Film Microelectrode Array with Hemispheric Electrodes for Subretinal Stimulation
Kim, N., Hong, Y., Cha, S., Kang, Y. N., Seo, H. W., Moon, H., Ahn, J., Intisar, A., Kim, M. S., Kim, S., et al. (2024) · Advanced Materials Technologies · doi:10.1002/admt.202302155 · Cited by 7 · see citing works
Perspectives on non-genetic optoelectronic modulation biointerfaces for advancing healthcare
Majmudar, A., Kim, S., Li, P., & Tian, B. (2024) · Med-X · doi:10.1007/s44258-024-00030-6 · Cited by 7 · see citing works
Honeycomb-type retinal device using chemically derived iridium oxide biointerfaces
Tso, K.-C., Fukunari, Y., Hagita, M., Haruta, M., Takehara, H., Tashiro, H., Sasagawa, K., Wu, P., & Ohta, J. (2021) · AIP Advances · doi:10.1063/5.0058457 · Cited by 7 · see citing works
Electrophysiological investigation of intact retina with soft printed organic neural interface
Vėbraitė, I., David‐Pur, M., Rand, D., Głowacki, E. D., & Hanein, Y. (2021) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac36ab · Cited by 7 · see citing works
Controlled assembly of retinal cells on fractal and Euclidean electrodes
Moslehi, S., Rowland, C., Smith, J. H., Watterson, W. J., Miller, D., Niell, C. M., Alemán, B., Perez, M.-T., & Taylor, R. P. (2022) · PLoS ONE · doi:10.1371/journal.pone.0265685 · Cited by 7 · see citing works
Explainable Machine Learning Predictions of Perceptual Sensitivity for Retinal Prostheses
Pogoncheff, G., Hu, Z., Rokem, A., & Beyeler, M. (2023) · doi:10.1101/2023.02.09.23285633 · Cited by 9 · see citing works
“With Argus II consisting of 60 electrodes, this procedure is time-consuming at best, but will quickly become infeasible as new devices are being developed that feature hundreds or even thousands of electrodes [6], [7].”
Developments in the design and microfabrication of photovoltaic retinal implants
Kusumanchi, P., Keller, S. S., & Davidsen, R. S. (2024) · Micro and Nano Engineering · doi:10.1016/j.mne.2024.100289 · Cited by 6 · see citing works
In the Eye of the Storm: Bi-Directional Electrophysiological Investigation of the Intact Retina
Vėbraitė, I., & Hanein, Y. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.829323 · Cited by 6 · see citing works
Deepak, C. S., Krishnan, A., & Narayan, K. S. (2022) · Journal of Neural Engineering · doi:10.1088/1741-2552/ac6f80 · Cited by 6 · see citing works
Moslehi, S., Rowland, C., Smith, J. H., Griffiths, W., Watterson, W. J., Niell, C. M., Alemán, B., Perez, M.-T., & Taylor, R. P. (2022) · Scientific Reports · doi:10.1038/s41598-022-21742-y · Cited by 6 · see citing works
Cojocaru, A.-E., Corna, A., Reh, M., & Zeck, G. M. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.1033738 · Cited by 5 · see citing works
Information Transmission through Biotic–Abiotic Interfaces to Restore or Enhance Human Function
Kelly, A. R., & Glover, D. J. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c00435 · Cited by 5 · see citing works
Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation
Corna, A., Gugujonović, K., Schiek, M., Bellapianta, A., Werginz, P., Ziller, A., Scharber, M. C., Salti, A., Bolz, M., Irimia‐Vladu, M., et al. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202515327 · Cited by 4 · see citing works
Photovoltaic, wireless wide‐field epiretinal prosthesis to treat retinitis pigmentosa
Schulz, A., Knoll, T., Jaeger, T., Harzic, R. L., Stracke, F., Wien, S., Olsommer, Y., Meiser, I., Wagner, S., Rammensee, M., et al. (2024) · Acta Ophthalmologica · doi:10.1111/aos.16733 · Cited by 4 · see citing works
Dagar, J., & Brown, T. M. (2022) · Nanotechnology · doi:10.1088/1361-6528/ac7883 · Cited by 4 · see citing works
Gustatory interface for operative assessment and taste decoding in patients with tongue cancer
Wang, X., Bai, G., Liang, J., Xie, Q., Chen, Z., Zhou, E., Li, M., Wei, X., Sun, L., Zhang, Z., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-53379-y · Cited by 4 · see citing works
Polz, M., Binter, K., Yallum, K. M., Rath, T., Nowakowska, M., Schimpel, C., Sommer, G., Ghaffari‐Tabrizi‐Wizsy, N., Banerji, N., Trimmel, G., et al. (2025) · Advanced Electronic Materials · doi:10.1002/aelm.202400899 · Cited by 4 · see citing works
An implantable epiretinal device for near-infrared light perception
Chung, W. G., Jeong, I., Lee, E., Cui, G., Jeong, H., Choi, M. S., Lee, S., an, S. E. M., Kim, E., Kim, S., et al. (2026) · Nature Electronics · doi:10.1038/s41928-026-01601-8 · Cited by 3 · see citing works
Engineering Materials for Neurotechnology
Ghezzi, D. (2023) · Advanced Engineering Materials · doi:10.1002/adem.202201412 · Cited by 2 · see citing works
Self-citationRahmani, A., & Eom, K. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1385567 · Cited by 3 · see citing works
A Functional BCI Model by the P2731 working group: Physiology
Hossaini, A., Valeriani, D., Nam, C. S., Ferrante, R., & Mahmud, M. (2021) · Brain-Computer Interfaces · doi:10.1080/2326263x.2021.1968665 · Cited by 3 · see citing works
Morphological Factors that Underlie Neural Sensitivity to Stimulation in the Retina
Raghuram, V., Werginz, P., Fried, S. I., & Timko, B. P. (2021) · Advanced NanoBiomed Research · doi:10.1002/anbr.202100069 · Cited by 3 · see citing works
A computational model to design wide field-of-view optic nerve neuroprostheses
Romeni, S., Luca, D. D., Pierantoni, L., Toni, L., Marino, G., Moccia, S., & Micera, S. (2024) · iScience · doi:10.1016/j.isci.2024.111321 · Cited by 2 · see citing works
A Cell-Type Selective Stimulation and Recording System for Retinal Ganglion Cells
Löhler, P., Albert, A., Erbslöh, A., Nruthyathi, Müller, F. W., & Seidl, K. (2023) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2023.3342465 · Cited by 2 · see citing works
Transparent and conformal microcoil arrays for spatially selective neuronal activation
Raghuram, V., Datye, A. D., Fried, S. I., & Timko, B. P. (2024) · Device · doi:10.1016/j.device.2024.100290 · Cited by 2 · see citing works
Neurostimulation in Neuro-Ophthalmology: Mechanisms and Therapeutic Potential
Shaheen, N., Khaled, M. B., Seo, S., Bezchlibnyk, Y. B., Flouty, O. E., & Bharmauria, V. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.115105 · Cited by 2 · see citing works
Relating the Morphology of Bipolar Neurons to Fractal Dimension
Brouse, B., Rowland, C., & Taylor, R. P. (2024) · Fractal and Fractional · doi:10.3390/fractalfract9010009 · Cited by 2 · see citing works
Lemaire, W., Benhouria, M., Koua, K., Tong, W., Martin-Hardy, G., Stamp, M. E. M., Ganesan, K., Gauthier, L.-P., Besrour, M., Ahnood, A., et al. (2024) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2024.3516492 · Cited by 1 · see citing works
Silicon Solar Cell-Integrated Flexible Retinal Prosthesis for Artificial Vision
Kim, C., Chung, S.-H., Kim, Y.-J., Roh, H., Lee, S.-K., Kim, Y., Lee, H., Park, J., Kang, M. G., & Im, M. (2025) · IEEE International Conference on Micro Electro Mechanical Systems (MEMS) · doi:10.1109/mems61431.2025.10917587 · Cited by 1 · see citing works
Implantable Nongenetic Optoelectronic Biointerfaces for Neuromodulation
Ye, J., Huang, J., Nie, W., Xu, J., Sheng, X., & Wang, H. (2025) · Advanced Photonics Research · doi:10.1002/adpr.202500176 · Cited by 1 · see citing works
Geometrical‐ and Substrate‐Dependent Photo Response of Thin‐Film Silicon‐Based Biointerfaces
Li, L., Zhang, Y., Gao, Y., Wang, Y., Wang, S., Gao, X., Chen, K., Yin, L., Sheng, X., & Yao, D. (2025) · Small Methods · doi:10.1002/smtd.202501228 · Cited by 1 · see citing works
Antibody-Modified Photovoltaic Biointerface for Neural Stimulation
Ou, W., Wen, N., Deng, H., Jiang, Q., & Liu, D. (2025) · ACS Nano · doi:10.1021/acsnano.5c12629 · Cited by 1 · see citing works
Hadji-Pulja, V., & Hulot, G. (2025) · doi:10.57088/978-3-7329-8750-4_12 · Cited by 1 · see citing works
Sensitive Imaging Using Graphene Photodetector Arrays with Passive Crosstalk Reduction Techniques
Homs, M., Nashashibi, S., Himstedt, E., Koepfli, S. M., Keller, K., Rieben, D., Fedoryshyn, Y. M., Haq, W., Zrenner, E., & Leuthold, J. (2025) · OSA Advanced Photonics Congress · doi:10.1364/noma.2025.now3c.2 · Cited by 1 · see citing works
Nanomaterial based photoacoustic interface for non-genetic neuromodulation
Li, D., Chen, G., Li, Y., Zheng, N., Du, Z., & Yang, C. (2026) · Nano Futures · doi:10.1088/2399-1984/ae44dc · Cited by 1 · see citing works
Guan, B., de la Perrelle, J. M., Zhang, J., Tunnadine, R. J., Malik, M., Li, R., Lim, R., & Griffith, M. J. (2026) · Biofabrication · doi:10.1088/1758-5090/ae6370 · Cited by 1 · see citing works
Self-organized nanoplasmonic artificial leaf for hot-carrier bioelectronic interfaces
Li, P., Liufu, M., Johnston, C. R., Pyo, Y., Zheng, Y., Yang, G., Kamath, A., Li, R., Liu, Y., Bassetto, C. A. Z., et al. (2026) · Nature Photonics · doi:10.1038/s41566-026-01949-5 · Cited by 1 · see citing works
Does Charge Balancing Ensure the Safety of the Electrical Stimulation and Is It Power Efficientƒ
Ranjandish, R., & Kim, G. (2023) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc40787.2023.10340438 · Cited by 1 · see citing works
Moslehi, S., Rowland, C., Smith, J. H., Watterson, W. J., Griffiths, W., Montgomery, R. D., Philliber, S., Marlow, C. A., Perez, M. T., & Taylor, R. P. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-47606-8_43 · Cited by 1 · see citing works
Evolution of Retinal Neuron Fractality When Interfacing with Carbon Nanotube Electrodes
Dillon, A. P., Moslehi, S., Brouse, B., Keremane, S., Philliber, S., Griffiths, W., Rowland, C., Smith, J. H., & Taylor, R. P. (2024) · Bioengineering · doi:10.3390/bioengineering11080823 · Cited by 1 · see citing works
Hinrichs, S., Placidet, L., Duret, A., Authié, C., Arleo, A., & Ghezzi, D. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad8b6f · Cited by 1 · see citing works
Self-citationBorda, E., Gaillet, V., Leccardi, M. J. I. A., Zollinger, E. G., Moreira, R. C., & Ghezzi, D. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.21.485100
Self-citationDesign and Implementation of Artificial Retinal Photoreceptors
Tripathi, M., & Yaduvanshi, R. S. (2022) · Asian Conference on Innovation in Technology (ASIANCON) · doi:10.1109/asiancon55314.2022.9909222
Löhler, P., Pickhinke, A., Erbslöh, A., & Seidl, K. (2023) · IEEE Interregional NEWCAS Conference (NEWCAS) · doi:10.1109/newcas57931.2023.10198191
Designing immersive interfaces for clinical applicationsPreprint
Chenais, N. A. L., & Görgen, A. (2024) · doi:10.31219/osf.io/gvs9d
Self-citationHinrichs, S., Tisserand, Y., Scialom, E., & Ghezzi, D. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.03.27.645647
Self-citationDevelopment and Evaluation of Multi-Module Retinal Devices for Artificial Vision Applications
Tso, K.-C., Sunaga, Y., Nakanishi, Y., Terasawa, Y., Haruta, M., Sasagawa, K., & Ohta, J. (2025) · Micromachines · doi:10.3390/mi16050580
- Authors
- Chenais, N. A. L., Airaghi Leccardi, M. J. I., & Ghezzi, D.
- Affiliations
- École Polytechnique Fédérale de Lausanne (CH)
- Corresponding author
- Ghezzi, Diego
- Venue
- Communications Materials
- Published
- 2021-03-05
- Volume
- 2
- Issue
- 1
- ISSN
- 2662-4443 (ISSN-L)
- OpenAlex
- W3134642074
- Cited by
- 110
- References
- 107
- Citations by year
- 2026: 11 · 2025: 20 · 2024: 32 · 2023: 17 · 2022: 18 · 2021: 10 · 2020: 2
- FWCI
- 8.90
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Communications Materials (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Velux Stiftung (1102)
- Gebert Rüf Stiftung (GRS-035/17)
- Fondation Pierre Mercier pour la Science Fondation Pro Visu
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinal Development and Disorders
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Advanced Memory and Neural Computing
- Keywords
- retinal prosthesis, epiretinal implants, retinitis pigmentosa, retinal ganglion cells, spatial resolution, artificial vision
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
